Drosophila melanogaster

0 known processes

kl-3 (Dmel_CG17629)

male fertility factor kl3

(Aliases: CG17629,CG40443,Y104b,kl-4,Lms3,Dmel\CG17629,ms(Y)104b,kl3)

kl-3 biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
spermatid differentiation GO:0048515 114 0.988
male gamete generation GO:0048232 201 0.882
spermatogenesis GO:0007283 200 0.801
cilium assembly GO:0042384 38 0.784
axoneme assembly GO:0035082 18 0.593
organelle assembly GO:0070925 198 0.538
cilium morphogenesis GO:0060271 39 0.533
spermatid development GO:0007286 98 0.516
cellular component assembly involved in morphogenesis GO:0010927 151 0.430
sperm axoneme assembly GO:0007288 13 0.233
microtubule bundle formation GO:0001578 27 0.203
sperm individualization GO:0007291 48 0.160
cilium organization GO:0044782 41 0.150
neurological system process GO:0050877 358 0.108
Fly
cell projection assembly GO:0030031 94 0.100
positive regulation of macromolecule metabolic process GO:0010604 405 0.074
cell motility GO:0048870 251 0.062
localization of cell GO:0051674 257 0.059
cellularization GO:0007349 90 0.056
eye development GO:0001654 323 0.051
regulation of protein metabolic process GO:0051246 256 0.047
centrosome cycle GO:0007098 137 0.046
transcription from rna polymerase ii promoter GO:0006366 368 0.045
phosphorylation GO:0016310 294 0.043
regulation of transcription from rna polymerase ii promoter GO:0006357 378 0.042
regulation of cellular protein metabolic process GO:0032268 243 0.041
cellular protein modification process GO:0006464 438 0.040
tissue morphogenesis GO:0048729 297 0.039
negative regulation of macromolecule biosynthetic process GO:0010558 270 0.038
single organism behavior GO:0044708 391 0.038
developmental programmed cell death GO:0010623 138 0.037
exocrine system development GO:0035272 162 0.036
small molecule metabolic process GO:0044281 305 0.035
sperm motility GO:0030317 12 0.032
regulation of programmed cell death GO:0043067 152 0.032
catabolic process GO:0009056 409 0.032
regulation of anatomical structure morphogenesis GO:0022603 242 0.031
protein modification process GO:0036211 438 0.030
cell division GO:0051301 248 0.030
kidney development GO:0001822 3 0.030
positive regulation of transcription from rna polymerase ii promoter GO:0045944 204 0.030
sensory perception GO:0007600 196 0.029
Fly
positive regulation of nitrogen compound metabolic process GO:0051173 354 0.029
sensory organ morphogenesis GO:0090596 260 0.029
mitotic spindle organization GO:0007052 220 0.028
regulation of synapse structure and activity GO:0050803 128 0.028
detection of stimulus GO:0051606 156 0.028
morphogenesis of an epithelium GO:0002009 276 0.028
wing disc morphogenesis GO:0007472 344 0.027
positive regulation of cellular biosynthetic process GO:0031328 316 0.027
eye morphogenesis GO:0048592 260 0.027
organelle fission GO:0048285 340 0.027
purine ribonucleoside metabolic process GO:0046128 127 0.027
organic substance transport GO:0071702 257 0.027
positive regulation of macromolecule biosynthetic process GO:0010557 283 0.027
digestive tract morphogenesis GO:0048546 127 0.026
organic substance catabolic process GO:1901575 308 0.026
microtubule organizing center organization GO:0031023 168 0.025
response to bacterium GO:0009617 198 0.025
regionalization GO:0003002 416 0.024
positive regulation of cell communication GO:0010647 250 0.024
positive regulation of response to stimulus GO:0048584 323 0.024
centrosome organization GO:0051297 163 0.024
positive regulation of catalytic activity GO:0043085 118 0.024
negative regulation of cellular metabolic process GO:0031324 382 0.023
gland morphogenesis GO:0022612 145 0.023
embryonic development via the syncytial blastoderm GO:0001700 148 0.023
positive regulation of cysteine type endopeptidase activity GO:2001056 24 0.022
transmembrane transport GO:0055085 139 0.022
positive regulation of hydrolase activity GO:0051345 78 0.022
post embryonic appendage morphogenesis GO:0035120 385 0.022
positive regulation of proteolysis GO:0045862 52 0.022
proteolysis GO:0006508 192 0.022
nucleoside metabolic process GO:0009116 127 0.022
salivary gland morphogenesis GO:0007435 145 0.022
positive regulation of molecular function GO:0044093 136 0.021
spindle organization GO:0007051 253 0.021
programmed cell death GO:0012501 257 0.021
ribonucleotide metabolic process GO:0009259 145 0.021
positive regulation of nucleobase containing compound metabolic process GO:0045935 332 0.021
compound eye development GO:0048749 307 0.021
positive regulation of signal transduction GO:0009967 223 0.020
regulation of catalytic activity GO:0050790 185 0.020
positive regulation of signaling GO:0023056 243 0.020
positive regulation of rna metabolic process GO:0051254 271 0.020
embryo development ending in birth or egg hatching GO:0009792 152 0.020
growth GO:0040007 359 0.020
compound eye morphogenesis GO:0001745 249 0.020
positive regulation of rna biosynthetic process GO:1902680 266 0.020
establishment of localization in cell GO:0051649 402 0.019
Fly
intracellular signal transduction GO:0035556 300 0.019
anterior posterior axis specification embryo GO:0008595 103 0.019
purine nucleotide metabolic process GO:0006163 146 0.019
single organism catabolic process GO:0044712 228 0.019
regulation of cellular amino acid metabolic process GO:0006521 0 0.019
positive regulation of cysteine type endopeptidase activity involved in apoptotic process GO:0043280 23 0.019
nucleoside phosphate metabolic process GO:0006753 162 0.019
aromatic compound catabolic process GO:0019439 166 0.019
phagocytosis GO:0006909 215 0.019
protein localization GO:0008104 284 0.019
autophagy GO:0006914 108 0.019
response to abiotic stimulus GO:0009628 341 0.019
negative regulation of developmental process GO:0051093 201 0.019
ribose phosphate metabolic process GO:0019693 145 0.019
nucleobase containing small molecule metabolic process GO:0055086 174 0.018
macromolecule catabolic process GO:0009057 161 0.018
segmentation GO:0035282 207 0.018
organic acid metabolic process GO:0006082 103 0.018
regulation of cysteine type endopeptidase activity GO:2000116 27 0.018
imaginal disc derived appendage morphogenesis GO:0035114 395 0.018
histolysis GO:0007559 102 0.018
appendage development GO:0048736 401 0.018
positive regulation of protein metabolic process GO:0051247 128 0.018
imaginal disc derived appendage development GO:0048737 399 0.018
cell cell signaling involved in cell fate commitment GO:0045168 210 0.018
oxoacid metabolic process GO:0043436 103 0.018
lipid storage GO:0019915 38 0.018
vesicle mediated transport GO:0016192 381 0.017
glycosyl compound metabolic process GO:1901657 127 0.017
regulation of intracellular signal transduction GO:1902531 236 0.017
purine nucleoside metabolic process GO:0042278 127 0.017
positive regulation of transcription dna templated GO:0045893 266 0.017
centrosome duplication GO:0051298 121 0.017
defense response to bacterium GO:0042742 178 0.017
death GO:0016265 284 0.017
cytoskeleton dependent cytokinesis GO:0061640 81 0.017
salivary gland cell autophagic cell death GO:0035071 83 0.017
positive regulation of apoptotic signaling pathway GO:2001235 4 0.017
sensory perception of mechanical stimulus GO:0050954 72 0.017
Fly
organonitrogen compound metabolic process GO:1901564 318 0.017
appendage morphogenesis GO:0035107 397 0.017
negative regulation of gene expression GO:0010629 387 0.016
response to external biotic stimulus GO:0043207 293 0.016
protein modification by small protein conjugation or removal GO:0070647 106 0.016
homeostatic process GO:0042592 199 0.016
body morphogenesis GO:0010171 2 0.016
response to oxygen containing compound GO:1901700 200 0.016
protein transmembrane transport GO:0071806 4 0.016
dorsal ventral pattern formation GO:0009953 133 0.016
organic cyclic compound catabolic process GO:1901361 168 0.016
positive regulation of gene expression GO:0010628 290 0.016
regulation of organelle organization GO:0033043 196 0.016
regulation of cysteine type endopeptidase activity involved in apoptotic process GO:0043281 25 0.016
cation transmembrane transport GO:0098655 88 0.016
secretion by cell GO:0032940 101 0.016
carbohydrate derivative metabolic process GO:1901135 217 0.016
positive regulation of cell death GO:0010942 69 0.016
regulation of cellular ketone metabolic process GO:0010565 3 0.015
rhythmic process GO:0048511 106 0.015
regulation of cell cycle GO:0051726 291 0.015
regulation of multicellular organismal development GO:2000026 414 0.015
regulation of cellular component biogenesis GO:0044087 201 0.015
response to lipopolysaccharide GO:0032496 4 0.015
response to extracellular stimulus GO:0009991 116 0.015
spermatocyte division GO:0048137 13 0.015
regulation of synapse organization GO:0050807 110 0.015
heterocycle catabolic process GO:0046700 166 0.015
regulation of cellular amine metabolic process GO:0033238 3 0.015
mitotic nuclear division GO:0007067 213 0.015
regulation of hydrolase activity GO:0051336 97 0.014
purine containing compound metabolic process GO:0072521 155 0.014
gland development GO:0048732 191 0.014
regulation of catabolic process GO:0009894 170 0.014
embryonic pattern specification GO:0009880 174 0.014
immune response GO:0006955 246 0.014
positive regulation of nucleic acid templated transcription GO:1903508 266 0.014
peptidyl amino acid modification GO:0018193 105 0.014
cellular response to dna damage stimulus GO:0006974 223 0.014
meiotic cell cycle GO:0051321 171 0.014
positive regulation of phosphate metabolic process GO:0045937 139 0.014
cell death GO:0008219 279 0.014
regulation of apoptotic process GO:0042981 130 0.014
cellular catabolic process GO:0044248 372 0.014
embryonic axis specification GO:0000578 107 0.014
monocarboxylic acid transport GO:0015718 3 0.014
response to wounding GO:0009611 94 0.014
regulation of proteolysis GO:0030162 87 0.014
cellular macromolecule localization GO:0070727 220 0.014
protein processing GO:0016485 68 0.014
endocytosis GO:0006897 310 0.014
response to glucose GO:0009749 2 0.013
amine metabolic process GO:0009308 12 0.013
lateral inhibition GO:0046331 206 0.013
positive regulation of programmed cell death GO:0043068 62 0.013
carboxylic acid metabolic process GO:0019752 92 0.013
retinal cell programmed cell death GO:0046666 25 0.013
drinking behavior GO:0042756 2 0.013
cellular amino acid metabolic process GO:0006520 61 0.013
tissue death GO:0016271 102 0.013
purine nucleoside triphosphate metabolic process GO:0009144 119 0.013
organophosphate metabolic process GO:0019637 195 0.013
autophagic cell death GO:0048102 83 0.013
regulation of cell death GO:0010941 173 0.013
response to organic cyclic compound GO:0014070 89 0.013
atp metabolic process GO:0046034 49 0.013
regulation of response to stress GO:0080134 200 0.012
nuclear division GO:0000280 332 0.012
circadian rhythm GO:0007623 105 0.012
regulation of organ morphogenesis GO:2000027 78 0.012
developmental growth GO:0048589 280 0.012
protein maturation GO:0051604 71 0.012
respiratory system development GO:0060541 213 0.012
digestive system development GO:0055123 149 0.012
epithelial cell differentiation GO:0030855 322 0.012
anion transport GO:0006820 41 0.012
ribonucleoside metabolic process GO:0009119 127 0.012
regulation of innate immune response GO:0045088 71 0.012
positive regulation of biosynthetic process GO:0009891 316 0.012
columnar cuboidal epithelial cell differentiation GO:0002065 256 0.012
hormone catabolic process GO:0042447 3 0.012
blastoderm segmentation GO:0007350 159 0.012
regulation of cellular catabolic process GO:0031329 157 0.012
negative regulation of signaling GO:0023057 219 0.012
morphogenesis of embryonic epithelium GO:0016331 94 0.012
convergent extension GO:0060026 2 0.012
aging GO:0007568 143 0.012
wound healing GO:0042060 75 0.012
endomembrane system organization GO:0010256 119 0.012
immune system process GO:0002376 347 0.012
epithelial cell development GO:0002064 274 0.011
male meiosis GO:0007140 52 0.011
nucleoside triphosphate metabolic process GO:0009141 120 0.011
ribonucleoside triphosphate metabolic process GO:0009199 119 0.011
single organism intracellular transport GO:1902582 207 0.011
Fly
negative regulation of cell cycle process GO:0010948 109 0.011
oocyte development GO:0048599 124 0.011
defense response to other organism GO:0098542 225 0.011
nucleoside monophosphate metabolic process GO:0009123 52 0.011
response to biotic stimulus GO:0009607 294 0.011
negative regulation of signal transduction GO:0009968 206 0.011
response to alcohol GO:0097305 95 0.011
activation of cysteine type endopeptidase activity involved in apoptotic process GO:0006919 16 0.011
embryonic morphogenesis GO:0048598 206 0.011
zymogen activation GO:0031638 20 0.011
developmental maturation GO:0021700 172 0.011
cellular response to starvation GO:0009267 61 0.011
negative regulation of response to stimulus GO:0048585 258 0.011
regulation of translation GO:0006417 56 0.011
response to starvation GO:0042594 97 0.011
defense response GO:0006952 300 0.011
positive regulation of phosphorus metabolic process GO:0010562 139 0.011
cellular protein localization GO:0034613 160 0.011
apoptotic process GO:0006915 159 0.011
regulation of cell differentiation GO:0045595 302 0.010
small gtpase mediated signal transduction GO:0007264 88 0.010
regulation of growth GO:0040008 233 0.010
purine nucleoside monophosphate metabolic process GO:0009126 50 0.010
regulation of molecular function GO:0065009 217 0.010
cellular ketone metabolic process GO:0042180 24 0.010
salivary gland development GO:0007431 162 0.010
cytokinesis GO:0000910 90 0.010
sterol homeostasis GO:0055092 4 0.010
negative regulation of cellular component organization GO:0051129 108 0.010
ion transport GO:0006811 145 0.010
tripartite regional subdivision GO:0007351 103 0.010
photoreceptor cell differentiation GO:0046530 170 0.010
cellular response to chemical stimulus GO:0070887 199 0.010
synapse organization GO:0050808 196 0.010
compound eye retinal cell programmed cell death GO:0046667 23 0.010
cytoplasmic transport GO:0016482 130 0.010
purine ribonucleoside monophosphate metabolic process GO:0009167 50 0.010

kl-3 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in fly and predicted with the fly functional network.

Disease DO term ID Size Probability Func Analog Org
disease of anatomical entity DOID:7 0 0.031
nervous system disease DOID:863 0 0.016
disease of metabolism DOID:0014667 0 0.012
inherited metabolic disorder DOID:655 0 0.011
central nervous system disease DOID:331 0 0.011