Drosophila melanogaster

68 known processes

para (Dmel_CG9907)

paralytic

(Aliases: l(1)14Da,CG9907,l(1)ESHS48,DmNa[[v]],Dmel\CG9907,Ocd,olfD,DmNa[[V]],sbl-1,DmNa[[v]]1,sbl)

para biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
ion transmembrane transport GO:0034220 122 0.999
synaptic transmission GO:0007268 288 0.994
response to abiotic stimulus GO:0009628 341 0.959
locomotory behavior GO:0007626 176 0.948
adult behavior GO:0030534 137 0.947
transmembrane transport GO:0055085 139 0.925
single organism behavior GO:0044708 391 0.905
neurological system process GO:0050877 358 0.889
learning or memory GO:0007611 141 0.847
cognition GO:0050890 141 0.794
response to toxic substance GO:0009636 22 0.759
adult locomotory behavior GO:0008344 76 0.722
reproductive behavior GO:0019098 122 0.660
male courtship behavior veined wing generated song production GO:0045433 20 0.637
regulation of synaptic transmission GO:0050804 69 0.525
multi organism behavior GO:0051705 175 0.500
developmental maturation GO:0021700 172 0.463
response to radiation GO:0009314 155 0.439
cell growth GO:0016049 108 0.433
cellular metal ion homeostasis GO:0006875 31 0.412
ion transport GO:0006811 145 0.411
regulation of circadian rhythm GO:0042752 49 0.407
regulation of membrane potential GO:0042391 35 0.399
multicellular organismal reproductive behavior GO:0033057 110 0.388
cation transmembrane transport GO:0098655 88 0.377
circadian rhythm GO:0007623 105 0.362
cellular cation homeostasis GO:0030003 38 0.338
synapse organization GO:0050808 196 0.304
response to organic substance GO:0010033 284 0.298
cellular ion homeostasis GO:0006873 39 0.291
neuromuscular synaptic transmission GO:0007274 67 0.273
regulation of synapse structure and activity GO:0050803 128 0.259
response to light stimulus GO:0009416 124 0.256
cation transport GO:0006812 110 0.234
membrane depolarization GO:0051899 4 0.230
response to heat GO:0009408 63 0.224
regulation of cell development GO:0060284 215 0.223
sensory perception GO:0007600 196 0.217
associative learning GO:0008306 65 0.214
cellular chemical homeostasis GO:0055082 40 0.209
positive regulation of signaling GO:0023056 243 0.207
regulation of transport GO:0051049 181 0.186
enzyme linked receptor protein signaling pathway GO:0007167 179 0.178
cellular homeostasis GO:0019725 80 0.172
divalent inorganic cation homeostasis GO:0072507 29 0.170
negative regulation of cell communication GO:0010648 223 0.166
regulation of excitatory postsynaptic membrane potential GO:0060079 3 0.165
g protein coupled receptor signaling pathway GO:0007186 136 0.158
cellular divalent inorganic cation homeostasis GO:0072503 23 0.158
developmental growth GO:0048589 280 0.157
male courtship behavior veined wing extension GO:0048065 22 0.157
cellular catabolic process GO:0044248 372 0.154
synapse assembly GO:0007416 143 0.149
circadian behavior GO:0048512 76 0.147
response to alkaloid GO:0043279 26 0.141
synaptic transmission cholinergic GO:0007271 9 0.137
response to endogenous stimulus GO:0009719 119 0.137
negative regulation of signaling GO:0023057 219 0.132
long term memory GO:0007616 62 0.130
response to nitrogen compound GO:1901698 90 0.127
multi multicellular organism process GO:0044706 123 0.123
programmed cell death GO:0012501 257 0.122
inorganic ion transmembrane transport GO:0098660 73 0.121
death GO:0016265 284 0.114
circadian sleep wake cycle GO:0042745 28 0.113
response to oxidative stress GO:0006979 86 0.112
negative regulation of biosynthetic process GO:0009890 277 0.110
actin filament based process GO:0030029 220 0.105
cell death GO:0008219 279 0.105
regulation of embryonic development GO:0045995 68 0.105
regulation of molecular function GO:0065009 217 0.103
response to oxygen containing compound GO:1901700 200 0.101
negative regulation of cell death GO:0060548 81 0.097
metal ion transport GO:0030001 74 0.094
chemosensory behavior GO:0007635 106 0.094
amine metabolic process GO:0009308 12 0.094
organic hydroxy compound metabolic process GO:1901615 83 0.092
positive regulation of response to stimulus GO:0048584 323 0.089
cellular response to endogenous stimulus GO:0071495 80 0.088
establishment of localization in cell GO:0051649 402 0.088
response to extracellular stimulus GO:0009991 116 0.087
multi organism reproductive behavior GO:0044705 121 0.086
negative regulation of cellular metabolic process GO:0031324 382 0.086
signal transduction by phosphorylation GO:0023014 107 0.084
neuron projection extension GO:1990138 32 0.082
positive regulation of cellular biosynthetic process GO:0031328 316 0.081
organonitrogen compound metabolic process GO:1901564 318 0.079
regulation of ion transport GO:0043269 39 0.077
inorganic cation transmembrane transport GO:0098662 61 0.076
actin cytoskeleton organization GO:0030036 206 0.076
memory GO:0007613 94 0.076
developmental cell growth GO:0048588 52 0.073
positive regulation of cell communication GO:0010647 250 0.071
olfactory behavior GO:0042048 97 0.071
spinal cord development GO:0021510 1 0.071
response to organic cyclic compound GO:0014070 89 0.070
learning GO:0007612 75 0.070
negative regulation of gene expression GO:0010629 387 0.069
catabolic process GO:0009056 409 0.069
positive regulation of cell proliferation GO:0008284 47 0.068
phosphorylation GO:0016310 294 0.067
embryo development ending in birth or egg hatching GO:0009792 152 0.066
organic substance transport GO:0071702 257 0.066
regulation of transmembrane transport GO:0034762 27 0.066
negative regulation of programmed cell death GO:0043069 72 0.065
neuron neuron synaptic transmission GO:0007270 14 0.064
response to organonitrogen compound GO:0010243 75 0.063
behavioral response to pain GO:0048266 3 0.062
regulation of cell cycle process GO:0010564 181 0.062
regulation of response to external stimulus GO:0032101 115 0.062
rhythmic process GO:0048511 106 0.061
regulation of circadian sleep wake cycle GO:0042749 25 0.060
calcium ion homeostasis GO:0055074 23 0.060
apoptotic process GO:0006915 159 0.060
response to mechanical stimulus GO:0009612 28 0.059
regulation of localization GO:0032879 275 0.059
male courtship behavior veined wing vibration GO:0016545 21 0.058
positive regulation of nucleobase containing compound metabolic process GO:0045935 332 0.056
transmembrane receptor protein serine threonine kinase signaling pathway GO:0007178 65 0.056
regulation of multicellular organismal development GO:2000026 414 0.056
regulation of epithelial cell proliferation GO:0050678 4 0.055
positive regulation of nitrogen compound metabolic process GO:0051173 354 0.054
positive regulation of rna metabolic process GO:0051254 271 0.054
regulation of programmed cell death GO:0043067 152 0.054
cell maturation GO:0048469 144 0.053
mapk cascade GO:0000165 107 0.052
cellular amino acid metabolic process GO:0006520 61 0.052
regulation of mitotic cell cycle GO:0007346 190 0.052
synaptic transmission glutamatergic GO:0035249 7 0.052
posttranscriptional regulation of gene expression GO:0010608 145 0.051
response to temperature stimulus GO:0009266 106 0.051
negative regulation of nitrogen compound metabolic process GO:0051172 265 0.051
regulation of cell proliferation GO:0042127 163 0.050
neuromuscular junction development GO:0007528 149 0.049
organic substance catabolic process GO:1901575 308 0.049
positive regulation of synaptic transmission GO:0050806 15 0.049
anatomical structure homeostasis GO:0060249 97 0.049
divalent inorganic cation transport GO:0072511 30 0.049
positive regulation of transcription from rna polymerase ii promoter GO:0045944 204 0.047
axonogenesis GO:0007409 290 0.047
cellular calcium ion homeostasis GO:0006874 21 0.046
regulation of cellular amine metabolic process GO:0033238 3 0.045
positive regulation of cellular component biogenesis GO:0044089 80 0.045
divalent metal ion transport GO:0070838 26 0.045
positive regulation of biosynthetic process GO:0009891 316 0.044
sensory perception of sound GO:0007605 56 0.044
heart process GO:0003015 37 0.043
transcription from rna polymerase ii promoter GO:0006366 368 0.042
regionalization GO:0003002 416 0.042
axon extension GO:0048675 32 0.042
positive regulation of nucleic acid templated transcription GO:1903508 266 0.042
central nervous system development GO:0007417 201 0.041
tube development GO:0035295 244 0.041
intracellular signal transduction GO:0035556 300 0.041
regulation of phosphorus metabolic process GO:0051174 210 0.041
cellular response to organic substance GO:0071310 132 0.041
developmental growth involved in morphogenesis GO:0060560 65 0.040
regulation of ion transmembrane transport GO:0034765 27 0.038
growth GO:0040007 359 0.038
positive regulation of multicellular organismal process GO:0051240 143 0.038
phenol containing compound metabolic process GO:0018958 57 0.036
regulation of behavior GO:0050795 75 0.036
cellular amine metabolic process GO:0044106 12 0.036
regulation of transcription from rna polymerase ii promoter GO:0006357 378 0.036
protein localization GO:0008104 284 0.036
carbohydrate derivative biosynthetic process GO:1901137 85 0.036
positive regulation of signal transduction GO:0009967 223 0.034
homeostatic process GO:0042592 199 0.034
regulation of immune system process GO:0002682 176 0.034
single organism biosynthetic process GO:0044711 206 0.033
mating GO:0007618 120 0.033
nucleobase containing compound catabolic process GO:0034655 165 0.033
positive regulation of macromolecule biosynthetic process GO:0010557 283 0.033
regulation of cell cycle phase transition GO:1901987 130 0.033
negative regulation of neuron death GO:1901215 18 0.033
regulation of phosphate metabolic process GO:0019220 210 0.032
regulation of cell cycle GO:0051726 291 0.032
regulation of cellular localization GO:0060341 136 0.032
regulation of organelle organization GO:0033043 196 0.032
brain development GO:0007420 120 0.032
response to growth factor GO:0070848 31 0.032
response to reactive oxygen species GO:0000302 24 0.032
positive regulation of cellular component organization GO:0051130 156 0.031
molting cycle process GO:0022404 29 0.031
positive regulation of rna biosynthetic process GO:1902680 266 0.031
single organism catabolic process GO:0044712 228 0.031
regulation of multi organism process GO:0043900 131 0.031
nucleobase containing small molecule metabolic process GO:0055086 174 0.030
cell division GO:0051301 248 0.030
macromolecular complex assembly GO:0065003 256 0.030
taxis GO:0042330 304 0.029
organic cyclic compound catabolic process GO:1901361 168 0.029
regulation of neurotransmitter secretion GO:0046928 14 0.029
positive regulation of transcription dna templated GO:0045893 266 0.029
positive regulation of developmental process GO:0051094 143 0.029
regulation of protein metabolic process GO:0051246 256 0.028
positive regulation of phosphorylation GO:0042327 87 0.028
positive regulation of phosphate metabolic process GO:0045937 139 0.028
ribonucleotide metabolic process GO:0009259 145 0.028
cellular response to chemical stimulus GO:0070887 199 0.028
cell proliferation GO:0008283 299 0.027
cellular response to growth factor stimulus GO:0071363 30 0.027
response to monosaccharide GO:0034284 4 0.027
purine nucleotide metabolic process GO:0006163 146 0.027
aggressive behavior GO:0002118 63 0.026
regulation of heart contraction GO:0008016 21 0.026
protein heterooligomerization GO:0051291 4 0.026
forebrain development GO:0030900 2 0.026
carboxylic acid metabolic process GO:0019752 92 0.026
dorsal ventral pattern formation GO:0009953 133 0.026
cytosolic calcium ion homeostasis GO:0051480 11 0.025
response to transforming growth factor beta GO:0071559 18 0.025
camera type eye development GO:0043010 4 0.025
immune response regulating signaling pathway GO:0002764 2 0.025
positive regulation of cell differentiation GO:0045597 64 0.025
response to nutrient levels GO:0031667 114 0.025
cation homeostasis GO:0055080 51 0.025
regulation of neurogenesis GO:0050767 158 0.025
regulation of intracellular signal transduction GO:1902531 236 0.025
blood circulation GO:0008015 26 0.025
regulation of cell differentiation GO:0045595 302 0.024
positive regulation of mitotic cell cycle GO:0045931 34 0.024
regulation of mapk cascade GO:0043408 92 0.024
regulation of catalytic activity GO:0050790 185 0.024
positive regulation of intracellular signal transduction GO:1902533 116 0.024
small molecule metabolic process GO:0044281 305 0.024
protein modification process GO:0036211 438 0.024
response to oxygen levels GO:0070482 59 0.023
regulation of mitotic cell cycle phase transition GO:1901990 130 0.023
regulation of hormone levels GO:0010817 40 0.023
courtship behavior GO:0007619 68 0.023
larval behavior GO:0030537 42 0.023
chemical homeostasis GO:0048878 92 0.022
response to hexose GO:0009746 3 0.022
positive regulation of gene expression GO:0010628 290 0.022
rhythmic behavior GO:0007622 76 0.022
cell type specific apoptotic process GO:0097285 38 0.022
positive regulation of transport GO:0051050 92 0.022
carbohydrate metabolic process GO:0005975 82 0.022
positive regulation of synaptic transmission glutamatergic GO:0051968 3 0.022
regulation of cellular component biogenesis GO:0044087 201 0.022
oxoacid metabolic process GO:0043436 103 0.022
regulation of cell death GO:0010941 173 0.022
short term memory GO:0007614 19 0.021
positive regulation of macromolecule metabolic process GO:0010604 405 0.021
positive regulation of molecular function GO:0044093 136 0.021
secretion GO:0046903 109 0.021
axon development GO:0061564 297 0.020
neuron recognition GO:0008038 101 0.020
regulation of neuron projection development GO:0010975 69 0.020
negative regulation of transforming growth factor beta receptor signaling pathway GO:0030512 4 0.020
regulation of vesicle mediated transport GO:0060627 59 0.020
detection of light stimulus GO:0009583 58 0.020
membrane organization GO:0061024 112 0.020
negative regulation of signal transduction GO:0009968 206 0.020
regulation of blood circulation GO:1903522 21 0.020
regulation of cellular response to growth factor stimulus GO:0090287 13 0.020
response to hormone GO:0009725 45 0.020
negative regulation of multicellular organismal process GO:0051241 142 0.020
neuron death GO:0070997 27 0.019
positive regulation of synapse assembly GO:0051965 29 0.019
regulation of transmembrane transporter activity GO:0022898 6 0.019
regulation of cell shape GO:0008360 113 0.019
ion homeostasis GO:0050801 55 0.019
neuromuscular process GO:0050905 21 0.019
oocyte maturation GO:0001556 3 0.019
cellular response to transforming growth factor beta stimulus GO:0071560 18 0.019
single organism carbohydrate metabolic process GO:0044723 72 0.019
smoothened signaling pathway GO:0007224 49 0.018
regulation of apoptotic process GO:0042981 130 0.018
sensory perception of mechanical stimulus GO:0050954 72 0.018
dendrite development GO:0016358 204 0.018
cellular response to dna damage stimulus GO:0006974 223 0.018
rhythmic synaptic transmission GO:0060024 2 0.018
nephron morphogenesis GO:0072028 3 0.018
regulation of phosphatase activity GO:0010921 3 0.018
multicellular organismal movement GO:0050879 3 0.018
protein complex assembly GO:0006461 200 0.018
purine ribonucleoside triphosphate metabolic process GO:0009205 119 0.017
adult walking behavior GO:0007628 9 0.017
positive regulation of cell death GO:0010942 69 0.017
establishment of protein localization GO:0045184 163 0.017
nucleoside triphosphate metabolic process GO:0009141 120 0.017
limb development GO:0060173 1 0.017
regulation of cellular amino acid metabolic process GO:0006521 0 0.017
reflex GO:0060004 6 0.017
regulation of cellular protein metabolic process GO:0032268 243 0.017
organelle assembly GO:0070925 198 0.017
response to other organism GO:0051707 293 0.017
organonitrogen compound biosynthetic process GO:1901566 117 0.017
cellular response to carbohydrate stimulus GO:0071322 4 0.017
cell cycle phase transition GO:0044770 140 0.017
head development GO:0060322 135 0.017
response to hydrogen peroxide GO:0042542 11 0.017
secretion by cell GO:0032940 101 0.016
regulation of phosphorylation GO:0042325 147 0.016
nucleoside phosphate metabolic process GO:0006753 162 0.016
cellular nitrogen compound catabolic process GO:0044270 165 0.016
response to hypoxia GO:0001666 53 0.016
regulation of cell projection organization GO:0031344 92 0.016
purine ribonucleotide metabolic process GO:0009150 145 0.016
metal ion homeostasis GO:0055065 44 0.016
cellular protein modification process GO:0006464 438 0.016
chromatin organization GO:0006325 207 0.015
cellular ketone metabolic process GO:0042180 24 0.015
protein complex biogenesis GO:0070271 201 0.015
protein phosphorylation GO:0006468 169 0.015
retina development in camera type eye GO:0060041 4 0.015
positive regulation of phosphorus metabolic process GO:0010562 139 0.015
sensory perception of light stimulus GO:0050953 12 0.015
regulation of dna metabolic process GO:0051052 34 0.015
negative regulation of transmembrane receptor protein serine threonine kinase signaling pathway GO:0090101 18 0.015
regulation of nervous system development GO:0051960 248 0.015
cellular component assembly involved in morphogenesis GO:0010927 151 0.015
embryonic development via the syncytial blastoderm GO:0001700 148 0.014
oviposition GO:0018991 19 0.014
response to alcohol GO:0097305 95 0.014
positive regulation of mapk cascade GO:0043410 63 0.014
circadian sleep wake cycle sleep GO:0050802 23 0.014
regulation of nucleotide metabolic process GO:0006140 62 0.014
macromolecule catabolic process GO:0009057 161 0.014
organic acid metabolic process GO:0006082 103 0.014
aromatic compound catabolic process GO:0019439 166 0.014
molting cycle GO:0042303 56 0.014
positive regulation of protein metabolic process GO:0051247 128 0.014
circadian sleep wake cycle process GO:0022410 24 0.014
negative regulation of response to stimulus GO:0048585 258 0.014
protein catabolic process GO:0030163 101 0.014
negative regulation of neuron apoptotic process GO:0043524 14 0.014
negative regulation of cellular biosynthetic process GO:0031327 277 0.013
regulation of gene expression epigenetic GO:0040029 128 0.013
negative regulation of apoptotic process GO:0043066 63 0.013
regulation of anatomical structure size GO:0090066 163 0.013
transmembrane receptor protein tyrosine kinase signaling pathway GO:0007169 116 0.013
cell cell junction assembly GO:0007043 38 0.013
regulation of neuron death GO:1901214 26 0.013
regulation of cellular ketone metabolic process GO:0010565 3 0.013
positive regulation of apoptotic process GO:0043065 47 0.013
purine ribonucleoside metabolic process GO:0046128 127 0.013
sensory perception of smell GO:0007608 80 0.013
cell motility GO:0048870 251 0.013
positive regulation of programmed cell death GO:0043068 62 0.013
negative regulation of transcription from rna polymerase ii promoter GO:0000122 119 0.013
regulation of transforming growth factor beta receptor signaling pathway GO:0017015 6 0.012
response to glucose GO:0009749 2 0.012
male gamete generation GO:0048232 201 0.012
chemotaxis GO:0006935 249 0.012
neuron apoptotic process GO:0051402 17 0.012
regulation of catabolic process GO:0009894 170 0.012
cranial nerve development GO:0021545 1 0.012
regulation of actin filament based process GO:0032970 42 0.012
single organism cellular localization GO:1902580 180 0.012
male mating behavior GO:0060179 70 0.012
immune response activating signal transduction GO:0002757 2 0.012
nucleoside metabolic process GO:0009116 127 0.012
regulation of growth GO:0040008 233 0.012
regulation of secretion by cell GO:1903530 39 0.012
localization of cell GO:0051674 257 0.012
vesicle mediated transport GO:0016192 381 0.012
endocytosis GO:0006897 310 0.012
purine nucleotide catabolic process GO:0006195 109 0.012
monovalent inorganic cation transport GO:0015672 40 0.011
regulation of cellular catabolic process GO:0031329 157 0.011
hindbrain development GO:0030902 2 0.011
body morphogenesis GO:0010171 2 0.011
monocarboxylic acid transport GO:0015718 3 0.011
response to external biotic stimulus GO:0043207 293 0.011
anion transmembrane transport GO:0098656 26 0.011
carbohydrate derivative metabolic process GO:1901135 217 0.011
regulation of system process GO:0044057 36 0.011
oocyte development GO:0048599 124 0.011
cellular response to oxygen containing compound GO:1901701 79 0.011
nitrogen compound transport GO:0071705 85 0.011
rhythmic excitation GO:0043179 1 0.011
regulation of hydrolase activity GO:0051336 97 0.011
regulation of reproductive process GO:2000241 54 0.011
germarium derived egg chamber formation GO:0007293 101 0.011
cellular response to hexose stimulus GO:0071331 1 0.011
oocyte differentiation GO:0009994 145 0.011
protein oligomerization GO:0051259 16 0.011
synaptic growth at neuromuscular junction GO:0051124 119 0.011
skeletal muscle adaptation GO:0043501 1 0.011
chromatin modification GO:0016568 147 0.011
mitotic cell cycle phase transition GO:0044772 138 0.011
morphogenesis of embryonic epithelium GO:0016331 94 0.011
positive regulation of growth GO:0045927 75 0.011
multicellular organismal aging GO:0010259 140 0.010
jump response GO:0007630 8 0.010
transforming growth factor beta receptor signaling pathway GO:0007179 16 0.010
gamma aminobutyric acid signaling pathway GO:0007214 2 0.010
immune response GO:0006955 246 0.010
hindgut development GO:0061525 58 0.010
positive regulation of cellular protein metabolic process GO:0032270 118 0.010
determination of adult lifespan GO:0008340 137 0.010
phagocytosis GO:0006909 215 0.010
regulation of locomotion GO:0040012 42 0.010
nucleotide metabolic process GO:0009117 161 0.010

para disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in fly and predicted with the fly functional network.

Disease DO term ID Size Probability Func Analog Org
disease of anatomical entity DOID:7 0 0.038
nervous system disease DOID:863 0 0.038
neuropathy DOID:870 0 0.019
neuromuscular disease DOID:440 0 0.015