Drosophila melanogaster

40 known processes

Frq2 (Dmel_CG5907)

Frequenin 2

(Aliases: Frq,frq,CG5907,Dmel\CG5907,frq2)

Frq2 biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
synaptic transmission GO:0007268 288 0.947
neurotransmitter secretion GO:0007269 35 0.823
neurotransmitter transport GO:0006836 37 0.764
regulation of synaptic transmission GO:0050804 69 0.598
secretion by cell GO:0032940 101 0.452
ion transmembrane transport GO:0034220 122 0.450
Rat
ion transport GO:0006811 145 0.388
Rat
regulation of synapse structure and activity GO:0050803 128 0.378
synapse organization GO:0050808 196 0.355
single organism behavior GO:0044708 391 0.336
metal ion transport GO:0030001 74 0.312
Rat
regulation of neurotransmitter levels GO:0001505 38 0.295
establishment of localization in cell GO:0051649 402 0.292
regulation of neurotransmitter secretion GO:0046928 14 0.288
signal release GO:0023061 49 0.262
neuromuscular junction development GO:0007528 149 0.254
divalent inorganic cation transport GO:0072511 30 0.240
Rat
cyclic nucleotide biosynthetic process GO:0009190 25 0.235
Fly
cation transport GO:0006812 110 0.228
Rat
regulation of localization GO:0032879 275 0.221
cgmp biosynthetic process GO:0006182 8 0.182
Fly
calcium ion transport GO:0006816 24 0.174
Rat
synaptic transmission glutamatergic GO:0035249 7 0.160
secretion GO:0046903 109 0.158
g protein coupled receptor signaling pathway GO:0007186 136 0.146
synaptic growth at neuromuscular junction GO:0051124 119 0.144
organonitrogen compound biosynthetic process GO:1901566 117 0.129
Fly
positive regulation of cgmp metabolic process GO:0030825 1 0.128
Fly
adult locomotory behavior GO:0008344 76 0.121
cyclic purine nucleotide metabolic process GO:0052652 25 0.121
Fly
regulation of cell differentiation GO:0045595 302 0.116
Rat
positive regulation of secretion GO:0051047 22 0.112
Rat
multi organism behavior GO:0051705 175 0.110
regulation of cellular localization GO:0060341 136 0.106
exocytosis GO:0006887 28 0.101
Rat
single organism membrane organization GO:0044802 93 0.097
regulation of vesicle mediated transport GO:0060627 59 0.097
Rat
regulation of cell development GO:0060284 215 0.092
Rat
regulation of excitatory postsynaptic membrane potential GO:0060079 3 0.091
intracellular signal transduction GO:0035556 300 0.090
Rat
sensory perception GO:0007600 196 0.089
inorganic cation transmembrane transport GO:0098662 61 0.085
Rat
regulation of secretion GO:0051046 44 0.084
positive regulation of exocytosis GO:0045921 4 0.083
Rat
regulation of phosphate metabolic process GO:0019220 210 0.081
Fly
positive regulation of synapse assembly GO:0051965 29 0.080
purine ribonucleotide biosynthetic process GO:0009152 28 0.077
Fly
positive regulation of nitrogen compound metabolic process GO:0051173 354 0.075
Fly
regulation of neurotransmitter transport GO:0051588 14 0.073
regulation of multicellular organismal development GO:2000026 414 0.072
Rat
mating behavior GO:0007617 106 0.071
regulation of synaptic growth at neuromuscular junction GO:0008582 89 0.071
divalent metal ion transport GO:0070838 26 0.069
Rat
positive regulation of transport GO:0051050 92 0.068
Rat
neuron neuron synaptic transmission GO:0007270 14 0.068
synaptic vesicle transport GO:0048489 50 0.067
carbohydrate derivative biosynthetic process GO:1901137 85 0.067
Fly
regulation of synaptic activity GO:0060025 9 0.066
single organism cellular localization GO:1902580 180 0.066
positive regulation of signaling GO:0023056 243 0.065
response to radiation GO:0009314 155 0.065
positive regulation of cyclase activity GO:0031281 9 0.065
Fly
regulation of transport GO:0051049 181 0.062
positive regulation of synaptic transmission GO:0050806 15 0.060
salt aversion GO:0035199 3 0.059
regulation of nucleotide biosynthetic process GO:0030808 14 0.058
Fly
transmembrane transport GO:0055085 139 0.056
Rat
rhythmic synaptic transmission GO:0060024 2 0.054
positive regulation of cellular biosynthetic process GO:0031328 316 0.053
Fly
positive regulation of synaptic transmission glutamatergic GO:0051968 3 0.053
positive regulation of response to stimulus GO:0048584 323 0.053
regulation of cyclic nucleotide biosynthetic process GO:0030802 13 0.053
Fly
segmentation GO:0035282 207 0.051
maintenance of location GO:0051235 73 0.050
negative regulation of synaptic growth at neuromuscular junction GO:0045886 39 0.050
cellular macromolecule localization GO:0070727 220 0.049
axis specification GO:0009798 167 0.049
establishment of vesicle localization GO:0051650 51 0.048
regulation of secretion by cell GO:1903530 39 0.047
organelle localization GO:0051640 148 0.047
protein heterooligomerization GO:0051291 4 0.045
neuromuscular synaptic transmission GO:0007274 67 0.045
positive regulation of purine nucleotide biosynthetic process GO:1900373 10 0.044
Fly
locomotory behavior GO:0007626 176 0.044
positive regulation of cell communication GO:0010647 250 0.042
receptor clustering GO:0043113 3 0.042
oocyte development GO:0048599 124 0.042
single organism intracellular transport GO:1902582 207 0.041
detection of stimulus GO:0051606 156 0.041
purine nucleotide metabolic process GO:0006163 146 0.040
Fly
adult behavior GO:0030534 137 0.040
vesicle mediated transport GO:0016192 381 0.040
Rat
regulation of synapse organization GO:0050807 110 0.040
regulation of purine nucleotide biosynthetic process GO:1900371 14 0.039
Fly
homeostatic process GO:0042592 199 0.039
positive regulation of secretion by cell GO:1903532 20 0.039
Rat
small molecule metabolic process GO:0044281 305 0.039
Fly
purine containing compound biosynthetic process GO:0072522 30 0.039
Fly
negative regulation of cell communication GO:0010648 223 0.038
cellular protein modification process GO:0006464 438 0.038
regulation of cyclic nucleotide metabolic process GO:0030799 13 0.038
Fly
membrane organization GO:0061024 112 0.038
rhythmic excitation GO:0043179 1 0.037
cellular protein localization GO:0034613 160 0.037
vesicle localization GO:0051648 55 0.037
ribonucleotide metabolic process GO:0009259 145 0.036
Fly
cyclic nucleotide metabolic process GO:0009187 28 0.036
Fly
positive regulation of cyclic nucleotide metabolic process GO:0030801 9 0.035
Fly
nucleoside phosphate biosynthetic process GO:1901293 34 0.034
Fly
regulation of cell projection organization GO:0031344 92 0.034
Rat
organic substance transport GO:0071702 257 0.034
regulation of phosphorus metabolic process GO:0051174 210 0.034
Fly
organophosphate biosynthetic process GO:0090407 46 0.034
Fly
organophosphate metabolic process GO:0019637 195 0.034
Fly
adenylate cyclase modulating g protein coupled receptor signaling pathway GO:0007188 17 0.033
catabolic process GO:0009056 409 0.033
cell projection assembly GO:0030031 94 0.033
learning or memory GO:0007611 141 0.032
positive regulation of phosphate metabolic process GO:0045937 139 0.032
Fly
detection of external stimulus GO:0009581 66 0.031
regulation of synaptic transmission glutamatergic GO:0051966 5 0.031
body morphogenesis GO:0010171 2 0.031
regulation of organelle organization GO:0033043 196 0.031
tube morphogenesis GO:0035239 191 0.031
Zebrafish
growth GO:0040007 359 0.031
positive regulation of signal transduction GO:0009967 223 0.030
embryonic pattern specification GO:0009880 174 0.030
cellular response to chemical stimulus GO:0070887 199 0.030
synaptic vesicle endocytosis GO:0048488 28 0.030
regulation of ion transport GO:0043269 39 0.029
Rat
enzyme linked receptor protein signaling pathway GO:0007167 179 0.029
developmental growth GO:0048589 280 0.028
axonogenesis GO:0007409 290 0.028
sensory perception of chemical stimulus GO:0007606 116 0.028
organonitrogen compound metabolic process GO:1901564 318 0.028
Fly
regulation of molecular function GO:0065009 217 0.028
Fly
ion homeostasis GO:0050801 55 0.028
tripartite regional subdivision GO:0007351 103 0.028
anatomical structure homeostasis GO:0060249 97 0.028
positive regulation of nucleobase containing compound metabolic process GO:0045935 332 0.027
Fly
developmental maturation GO:0021700 172 0.027
regulation of membrane potential GO:0042391 35 0.027
regulation of cellular component biogenesis GO:0044087 201 0.027
sensory perception of salty taste GO:0050914 3 0.027
social behavior GO:0035176 4 0.027
nucleobase containing small molecule metabolic process GO:0055086 174 0.026
Fly
multi organism reproductive behavior GO:0044705 121 0.026
neurological system process GO:0050877 358 0.026
regulation of anatomical structure morphogenesis GO:0022603 242 0.025
positive regulation of phosphorus metabolic process GO:0010562 139 0.025
Fly
positive regulation of biosynthetic process GO:0009891 316 0.025
Fly
regulation of neurogenesis GO:0050767 158 0.025
Rat
sensory organ morphogenesis GO:0090596 260 0.024
Zebrafish
phosphorylation GO:0016310 294 0.024
inorganic ion transmembrane transport GO:0098660 73 0.024
Rat
membrane depolarization GO:0051899 4 0.024
regulation of developmental growth GO:0048638 174 0.024
synaptic vesicle localization GO:0097479 53 0.023
regulation of intracellular signal transduction GO:1902531 236 0.023
developmental cell growth GO:0048588 52 0.023
positive regulation of purine nucleotide metabolic process GO:1900544 55 0.023
Fly
regulation of synapse assembly GO:0051963 94 0.023
cation homeostasis GO:0055080 51 0.023
positive regulation of neurotransmitter secretion GO:0001956 2 0.023
positive regulation of cellular component organization GO:0051130 156 0.022
synapse assembly GO:0007416 143 0.022
positive regulation of neurotransmitter transport GO:0051590 2 0.022
regulation of transmembrane transport GO:0034762 27 0.022
Rat
organic substance catabolic process GO:1901575 308 0.022
anion homeostasis GO:0055081 3 0.021
defense response to bacterium GO:0042742 178 0.021
purine ribonucleotide metabolic process GO:0009150 145 0.021
Fly
positive regulation of cellular component biogenesis GO:0044089 80 0.021
macromolecular complex assembly GO:0065003 256 0.021
columnar cuboidal epithelial cell development GO:0002066 249 0.021
cortical cytoskeleton organization GO:0030865 29 0.021
regulation of catalytic activity GO:0050790 185 0.021
Fly
regulation of transcription from rna polymerase ii promoter GO:0006357 378 0.020
oocyte construction GO:0007308 112 0.020
intracellular transport GO:0046907 228 0.020
mitotic dna damage checkpoint GO:0044773 74 0.020
eye development GO:0001654 323 0.020
ribonucleotide biosynthetic process GO:0009260 28 0.019
Fly
g protein coupled receptor signaling pathway coupled to cyclic nucleotide second messenger GO:0007187 17 0.019
membrane fusion GO:0061025 42 0.019
carbohydrate derivative metabolic process GO:1901135 217 0.019
Fly
detection of abiotic stimulus GO:0009582 66 0.019
membrane biogenesis GO:0044091 8 0.019
dendrite development GO:0016358 204 0.019
positive regulation of catalytic activity GO:0043085 118 0.019
Fly
taxis GO:0042330 304 0.019
regulation of lyase activity GO:0051339 14 0.019
Fly
regulation of metal ion transport GO:0010959 15 0.018
regulation of nervous system development GO:0051960 248 0.018
Rat
embryonic axis specification GO:0000578 107 0.018
mitotic g2 dna damage checkpoint GO:0007095 69 0.018
organelle fission GO:0048285 340 0.018
regulation of dendrite development GO:0050773 37 0.018
endocytosis GO:0006897 310 0.018
synaptic vesicle exocytosis GO:0016079 16 0.018
response to abiotic stimulus GO:0009628 341 0.018
synaptic vesicle recycling GO:0036465 28 0.018
tissue morphogenesis GO:0048729 297 0.018
apoptotic process GO:0006915 159 0.017
presynaptic membrane organization GO:0097090 4 0.017
blastoderm segmentation GO:0007350 159 0.017
carboxylic acid metabolic process GO:0019752 92 0.017
ribose phosphate biosynthetic process GO:0046390 28 0.017
Fly
nucleotide biosynthetic process GO:0009165 34 0.017
Fly
cellular amino acid metabolic process GO:0006520 61 0.017
cell adhesion GO:0007155 136 0.017
photoreceptor cell development GO:0042461 96 0.017
ribose phosphate metabolic process GO:0019693 145 0.017
Fly
nucleotide metabolic process GO:0009117 161 0.017
Fly
regulation of filopodium assembly GO:0051489 24 0.017
protein localization GO:0008104 284 0.016
purine containing compound metabolic process GO:0072521 155 0.016
Fly
cell death GO:0008219 279 0.016
small gtpase mediated signal transduction GO:0007264 88 0.016
regulation of cell cycle phase transition GO:1901987 130 0.016
open tracheal system development GO:0007424 204 0.016
eye morphogenesis GO:0048592 260 0.016
positive regulation of nucleotide biosynthetic process GO:0030810 10 0.016
Fly
detection of light stimulus GO:0009583 58 0.016
mitotic dna integrity checkpoint GO:0044774 75 0.016
morphogenesis of an epithelium GO:0002009 276 0.016
anterior posterior axis specification embryo GO:0008595 103 0.016
positive regulation of synaptic vesicle endocytosis GO:1900244 4 0.016
multicellular organismal reproductive behavior GO:0033057 110 0.016
single organismal cell cell adhesion GO:0016337 45 0.016
heterocycle catabolic process GO:0046700 166 0.016
negative regulation of developmental process GO:0051093 201 0.015
posttranscriptional regulation of gene expression GO:0010608 145 0.015
sensory perception of taste GO:0050909 25 0.015
transcription from rna polymerase ii promoter GO:0006366 368 0.015
behavioral response to pain GO:0048266 3 0.015
cognition GO:0050890 141 0.015
calcium ion transmembrane transport GO:0070588 17 0.015
Rat
regulation of mitotic cell cycle phase transition GO:1901990 130 0.015
positive regulation of transcription dna templated GO:0045893 266 0.015
organic acid metabolic process GO:0006082 103 0.015
inter male aggressive behavior GO:0002121 60 0.015
forebrain development GO:0030900 2 0.015
nucleoside phosphate metabolic process GO:0006753 162 0.015
Fly
cellular response to organic substance GO:0071310 132 0.015
regulation of protein metabolic process GO:0051246 256 0.015
single organism membrane fusion GO:0044801 42 0.015
single organism cell adhesion GO:0098602 47 0.015
response to organic substance GO:0010033 284 0.015
negative regulation of response to stimulus GO:0048585 258 0.015
regulation of phosphorylation GO:0042325 147 0.015
regulation of cellular amine metabolic process GO:0033238 3 0.015
carbohydrate metabolic process GO:0005975 82 0.015
endoderm formation GO:0001706 3 0.015
programmed cell death GO:0012501 257 0.014
regulation of neuron projection development GO:0010975 69 0.014
Rat
protein targeting GO:0006605 64 0.014
male courtship behavior GO:0008049 63 0.014
anterior posterior axis specification GO:0009948 109 0.014
positive regulation of neuromuscular synaptic transmission GO:1900075 4 0.014
response to ethanol GO:0045471 59 0.014
single organism catabolic process GO:0044712 228 0.014
regionalization GO:0003002 416 0.014
intracellular protein transport GO:0006886 104 0.014
larval locomotory behavior GO:0008345 27 0.014
death GO:0016265 284 0.014
muscle organ development GO:0007517 127 0.014
positive regulation of nucleic acid templated transcription GO:1903508 266 0.014
regulation of endocytosis GO:0030100 37 0.014
g2 dna damage checkpoint GO:0031572 69 0.014
positive regulation of intracellular signal transduction GO:1902533 116 0.014
axon extension GO:0048675 32 0.014
regulation of neuromuscular synaptic transmission GO:1900073 15 0.014
positive regulation of developmental process GO:0051094 143 0.014
endodermal cell differentiation GO:0035987 3 0.013
positive regulation of macromolecule metabolic process GO:0010604 405 0.013
regulation of gene expression epigenetic GO:0040029 128 0.013
l glutamate import GO:0051938 1 0.013
positive regulation of organelle organization GO:0010638 65 0.013
regulation of cellular amino acid metabolic process GO:0006521 0 0.013
response to biotic stimulus GO:0009607 294 0.013
regulation of cell cycle GO:0051726 291 0.013
mitotic cell cycle phase transition GO:0044772 138 0.013
cell cycle checkpoint GO:0000075 95 0.013
cellular ion homeostasis GO:0006873 39 0.013
establishment of protein localization GO:0045184 163 0.013
photoreceptor cell differentiation GO:0046530 170 0.013
regulation of cell cycle process GO:0010564 181 0.013
oocyte differentiation GO:0009994 145 0.013
single organism biosynthetic process GO:0044711 206 0.013
Fly
regulation of ras protein signal transduction GO:0046578 93 0.013
positive regulation of synaptic vesicle recycling GO:1903423 4 0.013
filopodium assembly GO:0046847 33 0.013
mitotic cell cycle checkpoint GO:0007093 88 0.013
appendage development GO:0048736 401 0.013
organelle fusion GO:0048284 46 0.013
organic cyclic compound catabolic process GO:1901361 168 0.013
oocyte axis specification GO:0007309 108 0.013
actin filament based process GO:0030029 220 0.012
regulation of catabolic process GO:0009894 170 0.012
nuclear division GO:0000280 332 0.012
connective tissue development GO:0061448 3 0.012
metal ion homeostasis GO:0055065 44 0.012
transmembrane receptor protein tyrosine kinase signaling pathway GO:0007169 116 0.012
regulation of cellular ketone metabolic process GO:0010565 3 0.012
spermatogenesis GO:0007283 200 0.012
protein phosphorylation GO:0006468 169 0.012
regulation of mapk cascade GO:0043408 92 0.012
regulation of programmed cell death GO:0043067 152 0.012
aggressive behavior GO:0002118 63 0.012
detection of stimulus involved in sensory perception GO:0050906 92 0.012
regulation of cell death GO:0010941 173 0.012
regulation of synaptic vesicle exocytosis GO:2000300 3 0.012
dendritic spine development GO:0060996 4 0.012
regulation of exocytosis GO:0017157 6 0.012
Rat
pole plasm assembly GO:0007315 61 0.012
dorsal ventral pattern formation GO:0009953 133 0.012
positive regulation of filopodium assembly GO:0051491 15 0.012
phosphatidylinositol mediated signaling GO:0048015 4 0.012
Rat
eye photoreceptor cell development GO:0042462 81 0.012
axon development GO:0061564 297 0.012
oocyte anterior posterior axis specification GO:0007314 72 0.011
cell cycle phase transition GO:0044770 140 0.011
synapse maturation GO:0060074 7 0.011
mitotic g2 m transition checkpoint GO:0044818 70 0.011
amine metabolic process GO:0009308 12 0.011
purine nucleoside triphosphate catabolic process GO:0009146 108 0.011
positive regulation of lyase activity GO:0051349 10 0.011
Fly
limb development GO:0060173 1 0.011
cellular amine metabolic process GO:0044106 12 0.011
chemotaxis GO:0006935 249 0.011
phagocytosis GO:0006909 215 0.011
maternal determination of anterior posterior axis embryo GO:0008358 74 0.011
multicellular organismal aging GO:0010259 140 0.011
determination of adult lifespan GO:0008340 137 0.011
anterior posterior pattern specification GO:0009952 136 0.011
neurotransmitter gated ion channel clustering GO:0072578 2 0.011
regulation of cell substrate adhesion GO:0010810 2 0.011
regulation of multi organism process GO:0043900 131 0.011
detection of mechanical stimulus involved in sensory perception of pain GO:0050966 2 0.011
spindle organization GO:0007051 253 0.011
mapk cascade GO:0000165 107 0.011
cytoplasm organization GO:0007028 64 0.011
negative regulation of cellular metabolic process GO:0031324 382 0.011
rna localization GO:0006403 115 0.011
positive regulation of nucleotide metabolic process GO:0045981 55 0.011
Fly
negative regulation of cell cycle process GO:0010948 109 0.011
cellular homeostasis GO:0019725 80 0.011
imaginal disc derived appendage development GO:0048737 399 0.011
response to oxygen containing compound GO:1901700 200 0.011
cellular response to growth factor stimulus GO:0071363 30 0.011
chemical homeostasis GO:0048878 92 0.011
cellular response to dna damage stimulus GO:0006974 223 0.011
camera type eye development GO:0043010 4 0.011
regulation of ion transmembrane transport GO:0034765 27 0.011
Rat
gene silencing GO:0016458 138 0.011
cellular ketone metabolic process GO:0042180 24 0.011
steroid catabolic process GO:0006706 1 0.010
positive regulation of protein metabolic process GO:0051247 128 0.010
detection of chemical stimulus GO:0009593 93 0.010
compound eye morphogenesis GO:0001745 249 0.010
lipid localization GO:0010876 54 0.010
cellular response to lipopolysaccharide GO:0071222 3 0.010
epithelial cell migration GO:0010631 148 0.010
myotube cell development GO:0014904 3 0.010
cellular lipid metabolic process GO:0044255 83 0.010
neuroblast proliferation GO:0007405 74 0.010
oxoacid metabolic process GO:0043436 103 0.010
regulation of ion transmembrane transporter activity GO:0032412 6 0.010
stem cell proliferation GO:0072089 88 0.010
regulation of lipid transport GO:0032368 3 0.010
divalent inorganic cation homeostasis GO:0072507 29 0.010
regulation of tube architecture open tracheal system GO:0035152 68 0.010
male gamete generation GO:0048232 201 0.010
ameboidal type cell migration GO:0001667 151 0.010
sensory perception of pain GO:0019233 4 0.010
positive regulation of molecular function GO:0044093 136 0.010
Fly
cell maturation GO:0048469 144 0.010
columnar cuboidal epithelial cell differentiation GO:0002065 256 0.010
post embryonic appendage morphogenesis GO:0035120 385 0.010

Frq2 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in fly and predicted with the fly functional network.

Disease DO term ID Size Probability Func Analog Org
disease of anatomical entity DOID:7 0 0.028
disease of metabolism DOID:0014667 0 0.023
cardiovascular system disease DOID:1287 0 0.019
respiratory system disease DOID:1579 0 0.017
lower respiratory tract disease DOID:0050161 0 0.017
bronchial disease DOID:1176 0 0.017
renal tubular transport disease DOID:447 0 0.016
kidney disease DOID:557 0 0.016
urinary system disease DOID:18 0 0.016
cancer DOID:162 0 0.015
disease of cellular proliferation DOID:14566 0 0.015
musculoskeletal system disease DOID:17 0 0.014
organ system cancer DOID:0050686 0 0.013
artery disease DOID:0050828 0 0.012
vascular disease DOID:178 0 0.012
central nervous system disease DOID:331 0 0.010
nervous system disease DOID:863 0 0.010