Drosophila melanogaster

13 known processes

dbr (Dmel_CG11371)

debra

(Aliases: BcDNA:LD26519,Dmel\CG11371,EP0456,EP456,Dbr,CG11371)

dbr biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
regionalization GO:0003002 416 0.627
wing disc morphogenesis GO:0007472 344 0.519
single organism behavior GO:0044708 391 0.438
imaginal disc derived wing morphogenesis GO:0007476 337 0.432
cellular protein modification process GO:0006464 438 0.412
regulation of multicellular organismal development GO:2000026 414 0.404
cellular response to chemical stimulus GO:0070887 199 0.363
post embryonic appendage morphogenesis GO:0035120 385 0.342
protein modification process GO:0036211 438 0.302
growth GO:0040007 359 0.299
regulation of anatomical structure morphogenesis GO:0022603 242 0.276
regulation of growth GO:0040008 233 0.269
protein modification by small protein conjugation GO:0032446 79 0.229
regulation of cell morphogenesis GO:0022604 163 0.226
small molecule metabolic process GO:0044281 305 0.211
positive regulation of biosynthetic process GO:0009891 316 0.187
developmental maturation GO:0021700 172 0.186
regulation of cell differentiation GO:0045595 302 0.173
humoral immune response GO:0006959 117 0.167
carbohydrate derivative metabolic process GO:1901135 217 0.166
mitotic spindle organization GO:0007052 220 0.164
gene silencing GO:0016458 138 0.161
negative regulation of signaling GO:0023057 219 0.160
enzyme linked receptor protein signaling pathway GO:0007167 179 0.136
response to organic substance GO:0010033 284 0.135
imaginal disc derived appendage development GO:0048737 399 0.133
negative regulation of cell communication GO:0010648 223 0.127
appendage development GO:0048736 401 0.125
cellular response to oxygen containing compound GO:1901701 79 0.121
protein transport GO:0015031 155 0.117
carboxylic acid metabolic process GO:0019752 92 0.115
positive regulation of nucleobase containing compound metabolic process GO:0045935 332 0.112
positive regulation of cellular biosynthetic process GO:0031328 316 0.104
cellular macromolecule localization GO:0070727 220 0.101
single organism cellular localization GO:1902580 180 0.097
blastoderm segmentation GO:0007350 159 0.095
cell migration GO:0016477 238 0.094
nucleobase containing small molecule metabolic process GO:0055086 174 0.091
protein modification by small protein conjugation or removal GO:0070647 106 0.090
learning or memory GO:0007611 141 0.089
organic acid metabolic process GO:0006082 103 0.086
eye photoreceptor cell differentiation GO:0001754 145 0.085
notch signaling pathway GO:0007219 120 0.083
epidermal growth factor receptor signaling pathway GO:0007173 58 0.080
negative regulation of response to stimulus GO:0048585 258 0.078
regulation of molecular function GO:0065009 217 0.078
organonitrogen compound metabolic process GO:1901564 318 0.077
photoreceptor cell differentiation GO:0046530 170 0.075
imaginal disc derived appendage morphogenesis GO:0035114 395 0.075
positive regulation of molecular function GO:0044093 136 0.072
positive regulation of transcription from rna polymerase ii promoter GO:0045944 204 0.071
purine ribonucleotide metabolic process GO:0009150 145 0.070
cell motility GO:0048870 251 0.070
regulation of notch signaling pathway GO:0008593 100 0.070
compound eye photoreceptor cell differentiation GO:0001751 140 0.067
activation of ras gtpase activity GO:0032856 6 0.066
embryonic pattern specification GO:0009880 174 0.065
intracellular protein transport GO:0006886 104 0.064
gland development GO:0048732 191 0.064
inter male aggressive behavior GO:0002121 60 0.063
immune effector process GO:0002252 98 0.062
eye development GO:0001654 323 0.062
compound eye morphogenesis GO:0001745 249 0.061
cell adhesion GO:0007155 136 0.059
cellular response to organic substance GO:0071310 132 0.059
cytoplasmic transport GO:0016482 130 0.057
regulation of gene silencing GO:0060968 63 0.056
regulation of catalytic activity GO:0050790 185 0.056
regulation of localization GO:0032879 275 0.056
appendage morphogenesis GO:0035107 397 0.055
nucleoside phosphate metabolic process GO:0006753 162 0.055
activation of rac gtpase activity GO:0032863 3 0.053
synapse organization GO:0050808 196 0.052
spindle organization GO:0007051 253 0.051
antimicrobial humoral response GO:0019730 99 0.051
purine containing compound metabolic process GO:0072521 155 0.050
eye photoreceptor cell development GO:0042462 81 0.050
regulation of cell development GO:0060284 215 0.050
oxoacid metabolic process GO:0043436 103 0.049
immune system process GO:0002376 347 0.048
regulation of vesicle mediated transport GO:0060627 59 0.047
thermotaxis GO:0043052 16 0.047
purine nucleoside catabolic process GO:0006152 112 0.047
negative regulation of notch signaling pathway GO:0045746 41 0.046
negative regulation of cellular biosynthetic process GO:0031327 277 0.046
urogenital system development GO:0001655 72 0.046
negative regulation of cellular metabolic process GO:0031324 382 0.046
ribonucleoside metabolic process GO:0009119 127 0.046
purine nucleoside metabolic process GO:0042278 127 0.045
positive regulation of macromolecule metabolic process GO:0010604 405 0.045
cellular ketone metabolic process GO:0042180 24 0.044
regulation of neuron differentiation GO:0045664 103 0.043
regulation of transport GO:0051049 181 0.043
protein localization GO:0008104 284 0.043
dendrite development GO:0016358 204 0.043
compound eye development GO:0048749 307 0.042
response to biotic stimulus GO:0009607 294 0.042
establishment of protein localization GO:0045184 163 0.041
vesicle mediated transport GO:0016192 381 0.041
protein targeting to nucleus GO:0044744 51 0.040
response to abiotic stimulus GO:0009628 341 0.040
response to temperature stimulus GO:0009266 106 0.040
response to oxygen containing compound GO:1901700 200 0.040
nucleoside catabolic process GO:0009164 112 0.040
glycosyl compound metabolic process GO:1901657 127 0.039
regulation of transcription from rna polymerase ii promoter GO:0006357 378 0.039
response to wounding GO:0009611 94 0.038
semaphorin plexin signaling pathway involved in regulation of photoreceptor cell axon guidance GO:2000305 2 0.038
purine ribonucleoside triphosphate metabolic process GO:0009205 119 0.038
tripartite regional subdivision GO:0007351 103 0.038
organic substance catabolic process GO:1901575 308 0.037
positive regulation of response to stimulus GO:0048584 323 0.037
compound eye photoreceptor fate commitment GO:0001752 36 0.036
regulation of cellular localization GO:0060341 136 0.036
cellular protein localization GO:0034613 160 0.036
ribonucleoside catabolic process GO:0042454 112 0.036
production of molecular mediator of immune response GO:0002440 46 0.035
digestive system development GO:0055123 149 0.035
regulation of cytoplasmic transport GO:1903649 47 0.035
cellular amino acid metabolic process GO:0006520 61 0.035
negative regulation of fibroblast growth factor receptor signaling pathway GO:0040037 2 0.035
cell fate determination GO:0001709 91 0.034
digestive tract development GO:0048565 149 0.034
regulation of developmental growth GO:0048638 174 0.034
compound eye photoreceptor development GO:0042051 78 0.034
negative regulation of macromolecule biosynthetic process GO:0010558 270 0.034
negative regulation of nitrogen compound metabolic process GO:0051172 265 0.033
negative regulation of developmental process GO:0051093 201 0.033
positive regulation of macromolecule biosynthetic process GO:0010557 283 0.033
regulation of neurogenesis GO:0050767 158 0.033
telencephalon development GO:0021537 2 0.032
ribonucleotide metabolic process GO:0009259 145 0.032
protein ubiquitination GO:0016567 70 0.032
positive regulation of multicellular organismal process GO:0051240 143 0.032
positive regulation of rna biosynthetic process GO:1902680 266 0.032
positive regulation of nitrogen compound metabolic process GO:0051173 354 0.032
chromatin organization GO:0006325 207 0.031
secretion GO:0046903 109 0.031
peptidyl amino acid modification GO:0018193 105 0.031
anterior posterior pattern specification GO:0009952 136 0.031
localization of cell GO:0051674 257 0.031
ribose phosphate metabolic process GO:0019693 145 0.031
regulation of cell shape GO:0008360 113 0.031
neuron projection guidance GO:0097485 241 0.030
immune response regulating signaling pathway GO:0002764 2 0.030
regulation of response to external stimulus GO:0032101 115 0.030
body morphogenesis GO:0010171 2 0.030
chemosensory behavior GO:0007635 106 0.029
regulation of chromatin silencing GO:0031935 36 0.029
heparin metabolic process GO:0030202 4 0.029
response to external biotic stimulus GO:0043207 293 0.028
synaptic transmission GO:0007268 288 0.028
ion transmembrane transport GO:0034220 122 0.028
cell recognition GO:0008037 102 0.028
multi organism behavior GO:0051705 175 0.027
purine nucleotide metabolic process GO:0006163 146 0.027
forebrain development GO:0030900 2 0.027
cellular catabolic process GO:0044248 372 0.026
protein localization to nucleus GO:0034504 55 0.026
developmental growth GO:0048589 280 0.026
locomotory behavior GO:0007626 176 0.026
nucleocytoplasmic transport GO:0006913 72 0.026
single organism biosynthetic process GO:0044711 206 0.026
purine ribonucleoside metabolic process GO:0046128 127 0.025
taxis GO:0042330 304 0.025
malpighian tubule development GO:0072002 64 0.025
muscle cell differentiation GO:0042692 103 0.025
purine ribonucleoside catabolic process GO:0046130 112 0.025
digestive tract morphogenesis GO:0048546 127 0.025
negative regulation of signal transduction GO:0009968 206 0.025
establishment of localization in cell GO:0051649 402 0.025
regulation of gene expression epigenetic GO:0040029 128 0.025
neurological system process GO:0050877 358 0.025
immune response GO:0006955 246 0.025
ribonucleoside triphosphate catabolic process GO:0009203 108 0.025
embryonic hindgut morphogenesis GO:0048619 48 0.024
heparan sulfate proteoglycan biosynthetic process polysaccharide chain biosynthetic process GO:0015014 5 0.024
regulation of circadian sleep wake cycle GO:0042749 25 0.024
regulation of ras protein signal transduction GO:0046578 93 0.024
negative regulation of multicellular organismal process GO:0051241 142 0.023
cell cell signaling involved in cell fate commitment GO:0045168 210 0.023
carbohydrate derivative catabolic process GO:1901136 118 0.023
organophosphate metabolic process GO:0019637 195 0.023
regulation of purine nucleotide metabolic process GO:1900542 62 0.023
regulation of anatomical structure size GO:0090066 163 0.023
spermatid development GO:0007286 98 0.023
purine nucleoside triphosphate metabolic process GO:0009144 119 0.023
nucleobase containing compound catabolic process GO:0034655 165 0.023
regulation of nucleoside metabolic process GO:0009118 50 0.023
positive regulation of signaling GO:0023056 243 0.022
negative regulation of rna metabolic process GO:0051253 251 0.022
positive regulation of nucleic acid templated transcription GO:1903508 266 0.022
compound eye cone cell differentiation GO:0042675 13 0.022
cellular nitrogen compound catabolic process GO:0044270 165 0.022
regulation of phosphate metabolic process GO:0019220 210 0.022
establishment of planar polarity GO:0001736 87 0.022
cell cycle g1 s phase transition GO:0044843 31 0.021
response to other organism GO:0051707 293 0.021
erbb signaling pathway GO:0038127 58 0.021
positive regulation of nucleoside metabolic process GO:0045979 47 0.021
regulation of protein transport GO:0051223 57 0.021
eye morphogenesis GO:0048592 260 0.021
carbohydrate derivative biosynthetic process GO:1901137 85 0.021
negative regulation of nucleobase containing compound metabolic process GO:0045934 261 0.020
endocytosis GO:0006897 310 0.020
sensory organ morphogenesis GO:0090596 260 0.020
response to lipid GO:0033993 38 0.020
chromatin modification GO:0016568 147 0.020
imaginal disc pattern formation GO:0007447 91 0.020
regulation of neuron projection development GO:0010975 69 0.019
regulation of photoreceptor cell differentiation GO:0046532 34 0.019
positive regulation of gene expression GO:0010628 290 0.019
nucleoside triphosphate metabolic process GO:0009141 120 0.019
negative regulation of cellular macromolecule biosynthetic process GO:2000113 267 0.019
nucleoside metabolic process GO:0009116 127 0.019
cell cycle phase transition GO:0044770 140 0.019
segmentation GO:0035282 207 0.019
ribonucleotide catabolic process GO:0009261 109 0.019
negative regulation of mitotic cell cycle GO:0045930 109 0.018
response to organic cyclic compound GO:0014070 89 0.018
positive regulation of nucleotide metabolic process GO:0045981 55 0.018
microtubule bundle formation GO:0001578 27 0.018
regulation of hemocyte proliferation GO:0035206 37 0.018
morphogenesis of a polarized epithelium GO:0001738 93 0.018
gtp metabolic process GO:0046039 72 0.018
organic substance transport GO:0071702 257 0.018
regulation of establishment of protein localization GO:0070201 61 0.018
regulation of erbb signaling pathway GO:1901184 42 0.018
tube morphogenesis GO:0035239 191 0.017
regulation of phosphorus metabolic process GO:0051174 210 0.017
regulation of synapse structure and activity GO:0050803 128 0.017
response to sterol GO:0036314 34 0.017
negative regulation of gene expression epigenetic GO:0045814 77 0.017
catabolic process GO:0009056 409 0.017
response to light stimulus GO:0009416 124 0.017
ribonucleoside triphosphate metabolic process GO:0009199 119 0.017
positive regulation of catalytic activity GO:0043085 118 0.017
regulation of immune effector process GO:0002697 52 0.016
protein dephosphorylation GO:0006470 27 0.016
transmembrane receptor protein tyrosine kinase signaling pathway GO:0007169 116 0.016
central nervous system development GO:0007417 201 0.016
regulation of epidermal growth factor receptor signaling pathway GO:0042058 42 0.016
sensory organ precursor cell division GO:0045035 10 0.016
connective tissue development GO:0061448 3 0.016
rhythmic behavior GO:0007622 76 0.016
regulation of nervous system development GO:0051960 248 0.016
salivary gland development GO:0007431 162 0.016
nucleotide metabolic process GO:0009117 161 0.016
wnt signaling pathway GO:0016055 98 0.016
purine ribonucleoside triphosphate catabolic process GO:0009207 108 0.015
chaeta development GO:0022416 97 0.015
actin filament organization GO:0007015 126 0.015
regulation of protein import into nucleus GO:0042306 28 0.015
regulation of axon extension involved in axon guidance GO:0048841 4 0.015
regulation of locomotion GO:0040012 42 0.015
cell death GO:0008219 279 0.015
lateral inhibition GO:0046331 206 0.015
developmental growth involved in morphogenesis GO:0060560 65 0.015
glycosyl compound catabolic process GO:1901658 112 0.015
chemotaxis GO:0006935 249 0.014
dorsal ventral pattern formation GO:0009953 133 0.014
adult behavior GO:0030534 137 0.014
regulation of cellular amino acid metabolic process GO:0006521 0 0.014
regulation of nucleocytoplasmic transport GO:0046822 35 0.014
memory GO:0007613 94 0.014
dephosphorylation GO:0016311 51 0.014
histone h3 k9 acetylation GO:0043970 3 0.014
phagocytosis GO:0006909 215 0.014
epithelium migration GO:0090132 148 0.014
rna interference GO:0016246 27 0.014
positive regulation of transcription dna templated GO:0045893 266 0.014
mitochondrial membrane organization GO:0007006 3 0.014
meiotic chromosome segregation GO:0045132 59 0.014
photoreceptor cell fate commitment GO:0046552 41 0.014
regulation of cellular component size GO:0032535 98 0.014
establishment of protein localization to plasma membrane GO:0090002 9 0.014
regulation of epithelial cell proliferation GO:0050678 4 0.013
regulation of nucleotide metabolic process GO:0006140 62 0.013
actin filament based process GO:0030029 220 0.013
posttranscriptional regulation of gene expression GO:0010608 145 0.013
response to endogenous stimulus GO:0009719 119 0.013
establishment of spindle localization GO:0051293 22 0.013
epithelial cell migration GO:0010631 148 0.013
regulation of protein localization GO:0032880 76 0.013
phosphatidylinositol mediated signaling GO:0048015 4 0.013
smoothened signaling pathway GO:0007224 49 0.013
regulation of cellular ketone metabolic process GO:0010565 3 0.012
positive regulation of phosphate metabolic process GO:0045937 139 0.012
anterior posterior axis specification embryo GO:0008595 103 0.012
negative regulation of gene expression GO:0010629 387 0.012
organonitrogen compound catabolic process GO:1901565 128 0.012
regulation of programmed cell death GO:0043067 152 0.012
rhythmic process GO:0048511 106 0.012
centriole replication GO:0007099 24 0.012
organophosphate catabolic process GO:0046434 112 0.012
cell maturation GO:0048469 144 0.012
multi multicellular organism process GO:0044706 123 0.012
protein targeting GO:0006605 64 0.012
cognition GO:0050890 141 0.012
axon guidance GO:0007411 233 0.012
nuclear transport GO:0051169 72 0.012
regulation of compound eye cone cell fate specification GO:0042682 4 0.012
positive regulation of signal transduction GO:0009967 223 0.012
response to radiation GO:0009314 155 0.012
cellular response to fibroblast growth factor stimulus GO:0044344 10 0.012
positive regulation of purine nucleotide metabolic process GO:1900544 55 0.012
intracellular transport GO:0046907 228 0.012
regulation of cytoskeleton organization GO:0051493 89 0.011
regulation of gtp catabolic process GO:0033124 44 0.011
cellular response to organic cyclic compound GO:0071407 32 0.011
phosphorylation GO:0016310 294 0.011
small gtpase mediated signal transduction GO:0007264 88 0.011
cellular amide metabolic process GO:0043603 80 0.011
centriole assembly GO:0098534 24 0.011
cellular hormone metabolic process GO:0034754 23 0.011
embryonic development via the syncytial blastoderm GO:0001700 148 0.011
peptide metabolic process GO:0006518 80 0.011
negative regulation of biosynthetic process GO:0009890 277 0.011
positive regulation of dendrite morphogenesis GO:0050775 9 0.011
mrna processing GO:0006397 104 0.011
hindbrain development GO:0030902 2 0.011
inositol lipid mediated signaling GO:0048017 4 0.011
circadian rhythm GO:0007623 105 0.011
muscle cell development GO:0055001 50 0.011
organonitrogen compound biosynthetic process GO:1901566 117 0.011
positive regulation of transport GO:0051050 92 0.011
transmembrane receptor protein serine threonine kinase signaling pathway GO:0007178 65 0.011
ras protein signal transduction GO:0007265 88 0.011
protein phosphorylation GO:0006468 169 0.011
single organism intracellular transport GO:1902582 207 0.011
response to ecdysone GO:0035075 34 0.011
chromosome organization GO:0051276 360 0.011
tube development GO:0035295 244 0.010
actin cytoskeleton organization GO:0030036 206 0.010
regulation of protein modification process GO:0031399 112 0.010
tissue migration GO:0090130 155 0.010
purine nucleotide catabolic process GO:0006195 109 0.010
positive regulation of proteolysis involved in cellular protein catabolic process GO:1903052 24 0.010
regulation of transmembrane transport GO:0034762 27 0.010
regulation of organelle organization GO:0033043 196 0.010
cortical cytoskeleton organization GO:0030865 29 0.010
positive regulation of purine nucleotide catabolic process GO:0033123 46 0.010
positive regulation of transcription factor import into nucleus GO:0042993 19 0.010
protein complex biogenesis GO:0070271 201 0.010
regulation of embryonic development GO:0045995 68 0.010
extracellular structure organization GO:0043062 46 0.010
regulation of immune system process GO:0002682 176 0.010

dbr disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in fly and predicted with the fly functional network.

Disease DO term ID Size Probability Func Analog Org
disease of anatomical entity DOID:7 0 0.021
nervous system disease DOID:863 0 0.013
cancer DOID:162 0 0.010
disease of cellular proliferation DOID:14566 0 0.010