Drosophila melanogaster

110 known processes

GABA-B-R1 (Dmel_CG15274)

metabotropic GABA-B receptor subtype 1

(Aliases: D-GABA[[B]]R1,BG:DS00929.6,Dmel\CG15274,anon-WO0170980.176,anon-WO0170980.175,CG15274,GB1,GABA[[B]],GABA[[B]]R1,D-Gaba1)

GABA-B-R1 biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
single organism behavior GO:0044708 391 0.098
eye morphogenesis GO:0048592 260 0.080
regulation of multicellular organismal development GO:2000026 414 0.073
eye development GO:0001654 323 0.070
neurological system process GO:0050877 358 0.069
cell cell signaling involved in cell fate commitment GO:0045168 210 0.057
lateral inhibition GO:0046331 206 0.055
sensory organ morphogenesis GO:0090596 260 0.053
g protein coupled receptor signaling pathway GO:0007186 136 0.050
compound eye development GO:0048749 307 0.048
protein modification process GO:0036211 438 0.047
cellular protein modification process GO:0006464 438 0.047
positive regulation of macromolecule metabolic process GO:0010604 405 0.044
death GO:0016265 284 0.043
positive regulation of nucleobase containing compound metabolic process GO:0045935 332 0.042
organelle assembly GO:0070925 198 0.042
intracellular signal transduction GO:0035556 300 0.042
phosphorylation GO:0016310 294 0.040
sensory perception GO:0007600 196 0.038
positive regulation of biosynthetic process GO:0009891 316 0.037
regulation of molecular function GO:0065009 217 0.037
adult behavior GO:0030534 137 0.037
organonitrogen compound metabolic process GO:1901564 318 0.036
positive regulation of cellular biosynthetic process GO:0031328 316 0.036
positive regulation of response to stimulus GO:0048584 323 0.035
compound eye morphogenesis GO:0001745 249 0.035
regulation of cell death GO:0010941 173 0.034
regulation of intracellular signal transduction GO:1902531 236 0.034
positive regulation of nitrogen compound metabolic process GO:0051173 354 0.033
transcription from rna polymerase ii promoter GO:0006366 368 0.033
response to organic substance GO:0010033 284 0.033
enzyme linked receptor protein signaling pathway GO:0007167 179 0.033
regulation of nervous system development GO:0051960 248 0.033
programmed cell death GO:0012501 257 0.032
transmembrane receptor protein tyrosine kinase signaling pathway GO:0007169 116 0.032
appendage morphogenesis GO:0035107 397 0.032
locomotory behavior GO:0007626 176 0.032
regulation of transcription from rna polymerase ii promoter GO:0006357 378 0.032
growth GO:0040007 359 0.032
cell death GO:0008219 279 0.032
positive regulation of rna metabolic process GO:0051254 271 0.031
regulation of phosphorus metabolic process GO:0051174 210 0.031
positive regulation of phosphate metabolic process GO:0045937 139 0.031
regulation of cellular protein metabolic process GO:0032268 243 0.031
positive regulation of nucleic acid templated transcription GO:1903508 266 0.031
negative regulation of cell communication GO:0010648 223 0.030
negative regulation of signal transduction GO:0009968 206 0.030
neuron projection guidance GO:0097485 241 0.030
appendage development GO:0048736 401 0.030
positive regulation of signaling GO:0023056 243 0.030
vesicle mediated transport GO:0016192 381 0.029
negative regulation of cellular metabolic process GO:0031324 382 0.029
forebrain development GO:0030900 2 0.029
negative regulation of signaling GO:0023057 219 0.029
protein phosphorylation GO:0006468 169 0.029
taxis GO:0042330 304 0.028
regionalization GO:0003002 416 0.028
small molecule metabolic process GO:0044281 305 0.028
compound eye photoreceptor cell differentiation GO:0001751 140 0.028
positive regulation of cell communication GO:0010647 250 0.028
regulation of phosphate metabolic process GO:0019220 210 0.028
negative regulation of response to stimulus GO:0048585 258 0.027
regulation of cellular component biogenesis GO:0044087 201 0.027
eye photoreceptor cell differentiation GO:0001754 145 0.027
wing disc morphogenesis GO:0007472 344 0.027
catabolic process GO:0009056 409 0.027
photoreceptor cell differentiation GO:0046530 170 0.027
cellular amino acid metabolic process GO:0006520 61 0.027
imaginal disc derived wing morphogenesis GO:0007476 337 0.027
cellular catabolic process GO:0044248 372 0.026
regulation of cell cycle GO:0051726 291 0.026
apoptotic process GO:0006915 159 0.026
ras protein signal transduction GO:0007265 88 0.026
positive regulation of rna biosynthetic process GO:1902680 266 0.026
endocytosis GO:0006897 310 0.026
organic acid metabolic process GO:0006082 103 0.026
positive regulation of multicellular organismal process GO:0051240 143 0.026
negative regulation of nitrogen compound metabolic process GO:0051172 265 0.025
regulation of phosphorylation GO:0042325 147 0.025
positive regulation of gene expression GO:0010628 290 0.025
photoreceptor cell development GO:0042461 96 0.025
eye photoreceptor cell development GO:0042462 81 0.025
positive regulation of signal transduction GO:0009967 223 0.025
regulation of catalytic activity GO:0050790 185 0.025
organic substance catabolic process GO:1901575 308 0.025
positive regulation of macromolecule biosynthetic process GO:0010557 283 0.024
chromosome organization GO:0051276 360 0.024
positive regulation of transcription dna templated GO:0045893 266 0.024
regulation of cell proliferation GO:0042127 163 0.024
protein localization GO:0008104 284 0.024
cognition GO:0050890 141 0.024
phagocytosis GO:0006909 215 0.024
positive regulation of phosphorus metabolic process GO:0010562 139 0.023
regulation of cell differentiation GO:0045595 302 0.023
cell proliferation GO:0008283 299 0.023
regulation of protein metabolic process GO:0051246 256 0.023
proteolysis GO:0006508 192 0.023
spindle organization GO:0007051 253 0.023
cellular component assembly involved in morphogenesis GO:0010927 151 0.023
kidney development GO:0001822 3 0.023
carboxylic acid metabolic process GO:0019752 92 0.023
axon development GO:0061564 297 0.022
post embryonic appendage morphogenesis GO:0035120 385 0.022
imaginal disc derived appendage development GO:0048737 399 0.022
imaginal disc derived appendage morphogenesis GO:0035114 395 0.022
regulation of localization GO:0032879 275 0.022
chemotaxis GO:0006935 249 0.022
positive regulation of transcription from rna polymerase ii promoter GO:0045944 204 0.022
cellular amine metabolic process GO:0044106 12 0.022
negative regulation of gene expression GO:0010629 387 0.021
sensory perception of smell GO:0007608 80 0.021
response to oxygen containing compound GO:1901700 200 0.021
oxoacid metabolic process GO:0043436 103 0.021
mrna metabolic process GO:0016071 124 0.021
nuclear division GO:0000280 332 0.021
cellular response to chemical stimulus GO:0070887 199 0.020
multi multicellular organism process GO:0044706 123 0.020
response to light stimulus GO:0009416 124 0.020
segmentation GO:0035282 207 0.020
regulation of mapk cascade GO:0043408 92 0.020
developmental maturation GO:0021700 172 0.020
compound eye photoreceptor development GO:0042051 78 0.020
small gtpase mediated signal transduction GO:0007264 88 0.020
cell division GO:0051301 248 0.020
rna splicing GO:0008380 83 0.020
rna processing GO:0006396 147 0.020
neuromuscular junction development GO:0007528 149 0.020
carbohydrate derivative metabolic process GO:1901135 217 0.020
nucleobase containing compound catabolic process GO:0034655 165 0.019
nucleobase containing small molecule metabolic process GO:0055086 174 0.019
macromolecular complex assembly GO:0065003 256 0.019
purine ribonucleotide metabolic process GO:0009150 145 0.019
negative regulation of cellular biosynthetic process GO:0031327 277 0.019
negative regulation of rna biosynthetic process GO:1902679 240 0.019
endomembrane system organization GO:0010256 119 0.019
developmental growth GO:0048589 280 0.019
sleep GO:0030431 49 0.019
positive regulation of molecular function GO:0044093 136 0.019
positive regulation of catalytic activity GO:0043085 118 0.019
store operated calcium entry GO:0002115 3 0.019
negative regulation of rna metabolic process GO:0051253 251 0.019
cellular modified amino acid metabolic process GO:0006575 45 0.019
anterior posterior pattern specification GO:0009952 136 0.018
regulation of synapse assembly GO:0051963 94 0.018
organophosphate metabolic process GO:0019637 195 0.018
response to radiation GO:0009314 155 0.018
neuropeptide signaling pathway GO:0007218 45 0.018
regulation of apoptotic process GO:0042981 130 0.018
cell projection assembly GO:0030031 94 0.018
regulation of cellular ketone metabolic process GO:0010565 3 0.018
neuron recognition GO:0008038 101 0.018
negative regulation of biosynthetic process GO:0009890 277 0.018
body morphogenesis GO:0010171 2 0.018
aromatic compound catabolic process GO:0019439 166 0.018
muscle structure development GO:0061061 224 0.018
anatomical structure homeostasis GO:0060249 97 0.018
response to abiotic stimulus GO:0009628 341 0.018
actin cytoskeleton organization GO:0030036 206 0.018
regulation of synaptic growth at neuromuscular junction GO:0008582 89 0.018
regulation of anatomical structure morphogenesis GO:0022603 242 0.018
connective tissue development GO:0061448 3 0.018
synaptic growth at neuromuscular junction GO:0051124 119 0.018
cellular homeostasis GO:0019725 80 0.018
cellular macromolecule localization GO:0070727 220 0.018
single organism catabolic process GO:0044712 228 0.018
adult locomotory behavior GO:0008344 76 0.018
organic cyclic compound catabolic process GO:1901361 168 0.018
regulation of programmed cell death GO:0043067 152 0.017
learning or memory GO:0007611 141 0.017
organelle fission GO:0048285 340 0.017
multi organism behavior GO:0051705 175 0.017
regulation of cellular catabolic process GO:0031329 157 0.017
negative regulation of nucleobase containing compound metabolic process GO:0045934 261 0.017
regulation of developmental growth GO:0048638 174 0.017
response to monosaccharide GO:0034284 4 0.017
rhythmic process GO:0048511 106 0.017
mitotic spindle organization GO:0007052 220 0.017
regulation of small gtpase mediated signal transduction GO:0051056 93 0.017
regulation of cellular amino acid metabolic process GO:0006521 0 0.017
purine ribonucleoside metabolic process GO:0046128 127 0.017
mapk cascade GO:0000165 107 0.017
localization of cell GO:0051674 257 0.017
response to endogenous stimulus GO:0009719 119 0.016
nucleoside catabolic process GO:0009164 112 0.016
cell recognition GO:0008037 102 0.016
axis specification GO:0009798 167 0.016
cilium assembly GO:0042384 38 0.016
rhabdomere development GO:0042052 38 0.016
positive regulation of developmental process GO:0051094 143 0.016
protein complex biogenesis GO:0070271 201 0.016
head development GO:0060322 135 0.016
positive regulation of protein metabolic process GO:0051247 128 0.016
regulation of growth GO:0040008 233 0.016
response to lipopolysaccharide GO:0032496 4 0.016
positive regulation of phosphorylation GO:0042327 87 0.016
positive regulation of intracellular signal transduction GO:1902533 116 0.016
establishment of localization in cell GO:0051649 402 0.016
sulfur compound metabolic process GO:0006790 59 0.016
muscle organ development GO:0007517 127 0.016
salivary gland development GO:0007431 162 0.016
actin filament based process GO:0030029 220 0.016
axonogenesis GO:0007409 290 0.016
organic substance transport GO:0071702 257 0.016
amine metabolic process GO:0009308 12 0.016
regulation of response to stress GO:0080134 200 0.016
embryonic pattern specification GO:0009880 174 0.016
regulation of mitotic cell cycle GO:0007346 190 0.016
single organism intracellular transport GO:1902582 207 0.016
axon guidance GO:0007411 233 0.016
negative regulation of multicellular organismal process GO:0051241 142 0.016
detection of chemical stimulus GO:0009593 93 0.015
blastoderm segmentation GO:0007350 159 0.015
signal transduction by phosphorylation GO:0023014 107 0.015
response to organic cyclic compound GO:0014070 89 0.015
regulation of ras protein signal transduction GO:0046578 93 0.015
purine containing compound metabolic process GO:0072521 155 0.015
nucleoside phosphate metabolic process GO:0006753 162 0.015
regulation of cellular amine metabolic process GO:0033238 3 0.015
cell motility GO:0048870 251 0.015
regulation of cell development GO:0060284 215 0.015
synapse assembly GO:0007416 143 0.015
camera type eye development GO:0043010 4 0.015
regulation of catabolic process GO:0009894 170 0.015
regulation of anatomical structure size GO:0090066 163 0.015
detection of chemical stimulus involved in sensory perception GO:0050907 75 0.015
morphogenesis of an epithelium GO:0002009 276 0.015
reproductive behavior GO:0019098 122 0.015
single organism biosynthetic process GO:0044711 206 0.015
circadian behavior GO:0048512 76 0.015
regulation of alternative mrna splicing via spliceosome GO:0000381 60 0.015
negative regulation of transcription dna templated GO:0045892 237 0.015
telencephalon development GO:0021537 2 0.015
cell cell adhesion via plasma membrane adhesion molecules GO:0098742 26 0.015
alternative mrna splicing via spliceosome GO:0000380 60 0.014
cell migration GO:0016477 238 0.014
regulation of transport GO:0051049 181 0.014
cellular response to molecule of bacterial origin GO:0071219 3 0.014
regulation of mrna metabolic process GO:1903311 72 0.014
nucleoside metabolic process GO:0009116 127 0.014
sensory perception of chemical stimulus GO:0007606 116 0.014
regulation of cell shape GO:0008360 113 0.014
regulation of rna splicing GO:0043484 69 0.014
intracellular transport GO:0046907 228 0.014
anterior posterior axis specification embryo GO:0008595 103 0.014
regulation of cell morphogenesis GO:0022604 163 0.014
hindbrain development GO:0030902 2 0.014
immune response activating signal transduction GO:0002757 2 0.014
response to biotic stimulus GO:0009607 294 0.014
regulation of membrane potential GO:0042391 35 0.014
positive regulation of cell motility GO:2000147 3 0.014
cell maturation GO:0048469 144 0.014
response to other organism GO:0051707 293 0.014
negative regulation of macromolecule biosynthetic process GO:0010558 270 0.014
response to alcohol GO:0097305 95 0.014
protein complex assembly GO:0006461 200 0.014
ribonucleotide metabolic process GO:0009259 145 0.014
response to organonitrogen compound GO:0010243 75 0.014
mrna splicing via spliceosome GO:0000398 73 0.014
dendrite morphogenesis GO:0048813 199 0.014
purine nucleoside triphosphate metabolic process GO:0009144 119 0.014
regulation of organelle organization GO:0033043 196 0.014
epidermal growth factor receptor signaling pathway GO:0007173 58 0.014
estrogen metabolic process GO:0008210 1 0.014
protein maturation GO:0051604 71 0.014
response to glucose GO:0009749 2 0.014
cellular response to dna damage stimulus GO:0006974 223 0.014
regulation of i kappab kinase nf kappab signaling GO:0043122 2 0.013
regulation of synapse structure and activity GO:0050803 128 0.013
establishment of protein localization GO:0045184 163 0.013
erbb signaling pathway GO:0038127 58 0.013
positive regulation of cellular protein metabolic process GO:0032270 118 0.013
chromatin organization GO:0006325 207 0.013
purine ribonucleoside triphosphate metabolic process GO:0009205 119 0.013
nephron development GO:0072006 3 0.013
response to organophosphorus GO:0046683 2 0.013
cellular nitrogen compound catabolic process GO:0044270 165 0.013
positive regulation of catabolic process GO:0009896 105 0.013
single organism cellular localization GO:1902580 180 0.013
positive regulation of cellular catabolic process GO:0031331 95 0.013
cellular ketone metabolic process GO:0042180 24 0.013
carbohydrate derivative biosynthetic process GO:1901137 85 0.013
glycosyl compound metabolic process GO:1901657 127 0.013
rna splicing via transesterification reactions GO:0000375 73 0.013
regulation of cell cycle process GO:0010564 181 0.013
salivary gland morphogenesis GO:0007435 145 0.013
rhythmic behavior GO:0007622 76 0.013
regulation of immune system process GO:0002682 176 0.013
response to alkaloid GO:0043279 26 0.013
secretion GO:0046903 109 0.013
negative regulation of cellular protein metabolic process GO:0032269 85 0.013
regulation of immune response GO:0050776 118 0.013
regulation of epidermal growth factor receptor signaling pathway GO:0042058 42 0.013
organonitrogen compound biosynthetic process GO:1901566 117 0.013
regulation of mrna splicing via spliceosome GO:0048024 64 0.013
mating GO:0007618 120 0.013
negative regulation of protein metabolic process GO:0051248 85 0.013
nucleotide metabolic process GO:0009117 161 0.013
response to nitrogen compound GO:1901698 90 0.013
purine nucleotide metabolic process GO:0006163 146 0.013
bolwig s organ development GO:0055034 8 0.013
glycosyl compound catabolic process GO:1901658 112 0.013
posttranscriptional regulation of gene expression GO:0010608 145 0.013
anterior posterior axis specification GO:0009948 109 0.012
negative regulation of developmental process GO:0051093 201 0.012
mitotic nuclear division GO:0007067 213 0.012
mitotic cell cycle phase transition GO:0044772 138 0.012
organonitrogen compound catabolic process GO:1901565 128 0.012
mrna processing GO:0006397 104 0.012
negative regulation of cell death GO:0060548 81 0.012
chromatin modification GO:0016568 147 0.012
steroid catabolic process GO:0006706 1 0.012
cilium organization GO:0044782 41 0.012
cell adhesion GO:0007155 136 0.012
regulation of response to biotic stimulus GO:0002831 63 0.012
developmental programmed cell death GO:0010623 138 0.012
cilium morphogenesis GO:0060271 39 0.012
purine nucleoside metabolic process GO:0042278 127 0.012
embryonic axis specification GO:0000578 107 0.012
nucleoside phosphate catabolic process GO:1901292 110 0.012
dorsal ventral pattern formation GO:0009953 133 0.012
detection of stimulus involved in sensory perception GO:0050906 92 0.012
detection of stimulus GO:0051606 156 0.012
positive regulation of cell migration GO:0030335 2 0.012
aging GO:0007568 143 0.012
meiotic cell cycle GO:0051321 171 0.012
ribonucleoside triphosphate metabolic process GO:0009199 119 0.012
cell cycle phase transition GO:0044770 140 0.012
ion transport GO:0006811 145 0.012
camera type eye morphogenesis GO:0048593 2 0.012
positive regulation of lipid storage GO:0010884 4 0.012
open tracheal system development GO:0007424 204 0.012
purine containing compound catabolic process GO:0072523 112 0.012
regulation of cellular response to stress GO:0080135 89 0.012
cellular response to organic substance GO:0071310 132 0.012
immune response regulating signaling pathway GO:0002764 2 0.012
cellular protein localization GO:0034613 160 0.012
transmembrane transport GO:0055085 139 0.012
synapse organization GO:0050808 196 0.012
cellular response to carbohydrate stimulus GO:0071322 4 0.012
regulation of circadian rhythm GO:0042752 49 0.012
positive regulation of cellular amine metabolic process GO:0033240 0 0.012
rho protein signal transduction GO:0007266 14 0.012
protein processing GO:0016485 68 0.012
carbohydrate derivative catabolic process GO:1901136 118 0.012
purine nucleotide catabolic process GO:0006195 109 0.012
autophagy GO:0006914 108 0.012
negative regulation of nucleic acid templated transcription GO:1903507 240 0.012
immune system process GO:0002376 347 0.012
mesenchymal cell differentiation GO:0048762 1 0.011
establishment or maintenance of cell polarity GO:0007163 167 0.011
regulation of multi organism process GO:0043900 131 0.011
purine nucleoside triphosphate catabolic process GO:0009146 108 0.011
embryonic development via the syncytial blastoderm GO:0001700 148 0.011
protein transport GO:0015031 155 0.011
embryo development ending in birth or egg hatching GO:0009792 152 0.011
regulation of proteolysis GO:0030162 87 0.011
mushroom body development GO:0016319 70 0.011
regulation of cell projection organization GO:0031344 92 0.011
regulation of mitotic cell cycle phase transition GO:1901990 130 0.011
negative regulation of cellular macromolecule biosynthetic process GO:2000113 267 0.011
sex differentiation GO:0007548 81 0.011
negative regulation of programmed cell death GO:0043069 72 0.011
response to hexose GO:0009746 3 0.011
hematopoietic progenitor cell differentiation GO:0002244 1 0.011
positive regulation of mapk cascade GO:0043410 63 0.011
organophosphate catabolic process GO:0046434 112 0.011
tripartite regional subdivision GO:0007351 103 0.011
gland morphogenesis GO:0022612 145 0.011
retina development in camera type eye GO:0060041 4 0.011
nephron epithelium development GO:0072009 3 0.011
purine nucleoside catabolic process GO:0006152 112 0.011
ribose phosphate metabolic process GO:0019693 145 0.011
molting cycle chitin based cuticle GO:0007591 56 0.011
purine ribonucleoside catabolic process GO:0046130 112 0.011
kidney morphogenesis GO:0060993 3 0.011
salt aversion GO:0035199 3 0.011
negative regulation of cell differentiation GO:0045596 143 0.011
ribonucleotide catabolic process GO:0009261 109 0.011
ribonucleoside catabolic process GO:0042454 112 0.011
notch signaling pathway GO:0007219 120 0.011
regulation of response to external stimulus GO:0032101 115 0.011
dendrite development GO:0016358 204 0.011
regulation of hydrolase activity GO:0051336 97 0.011
golgi organization GO:0007030 66 0.011
humoral immune response GO:0006959 117 0.011
sensory perception of pain GO:0019233 4 0.011
heterocycle catabolic process GO:0046700 166 0.011
cellular macromolecular complex assembly GO:0034622 153 0.011
regulation of cell cycle phase transition GO:1901987 130 0.011
multicellular organismal reproductive behavior GO:0033057 110 0.011
cytoplasmic transport GO:0016482 130 0.011
nucleotide catabolic process GO:0009166 109 0.011
ribonucleoside metabolic process GO:0009119 127 0.011
central nervous system development GO:0007417 201 0.011
homeostatic process GO:0042592 199 0.010
nucleoside triphosphate catabolic process GO:0009143 108 0.010
rna localization GO:0006403 115 0.010
synaptic transmission GO:0007268 288 0.010
limb development GO:0060173 1 0.010
response to external biotic stimulus GO:0043207 293 0.010
hindgut development GO:0061525 58 0.010
kidney epithelium development GO:0072073 3 0.010
respiratory system development GO:0060541 213 0.010
purine ribonucleoside triphosphate catabolic process GO:0009207 108 0.010
spermatid development GO:0007286 98 0.010
gland development GO:0048732 191 0.010
cation transmembrane transport GO:0098655 88 0.010
positive regulation of hydrolase activity GO:0051345 78 0.010
cytoskeleton dependent cytokinesis GO:0061640 81 0.010
tissue morphogenesis GO:0048729 297 0.010
positive regulation of developmental growth GO:0048639 62 0.010
mesenchymal cell development GO:0014031 1 0.010
cell growth GO:0016049 108 0.010
regulation of notch signaling pathway GO:0008593 100 0.010
eye antennal disc development GO:0035214 60 0.010
synaptic target recognition GO:0008039 45 0.010
antimicrobial humoral response GO:0019730 99 0.010
positive regulation of nucleotide metabolic process GO:0045981 55 0.010
regulation of protein modification process GO:0031399 112 0.010
single organism membrane organization GO:0044802 93 0.010

GABA-B-R1 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in fly and predicted with the fly functional network.

Disease DO term ID Size Probability Func Analog Org
disease of anatomical entity DOID:7 0 0.030
nervous system disease DOID:863 0 0.017
musculoskeletal system disease DOID:17 0 0.013
disease of metabolism DOID:0014667 0 0.011
central nervous system disease DOID:331 0 0.010