Drosophila melanogaster

14 known processes

Hex-A (Dmel_CG3001)

Hexokinase A

(Aliases: HEX-A,HK,Hex,HEX,Hex-A:B,Dmel\CG3001,DM1,CG3001)

Hex-A biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
lateral inhibition GO:0046331 206 0.198
Fly
neurological system process GO:0050877 358 0.153
regulation of cell cycle process GO:0010564 181 0.137
regulation of cell cycle GO:0051726 291 0.092
meiotic cell cycle process GO:1903046 132 0.090
cell cell signaling involved in cell fate commitment GO:0045168 210 0.086
Fly
macromolecular complex assembly GO:0065003 256 0.078
positive regulation of macromolecule biosynthetic process GO:0010557 283 0.078
Human
appendage development GO:0048736 401 0.075
epithelial cell differentiation GO:0030855 322 0.075
oxidoreduction coenzyme metabolic process GO:0006733 2 0.073
Mouse
organonitrogen compound metabolic process GO:1901564 318 0.073
Mouse
nad metabolic process GO:0019674 1 0.065
posttranscriptional gene silencing GO:0016441 46 0.064
endocytosis GO:0006897 310 0.063
ovarian follicle cell development GO:0030707 248 0.062
eye development GO:0001654 323 0.061
regulation of growth GO:0040008 233 0.061
regulation of multicellular organismal development GO:2000026 414 0.060
localization of cell GO:0051674 257 0.060
regulation of cell death GO:0010941 173 0.057
gene silencing GO:0016458 138 0.057
negative regulation of rna biosynthetic process GO:1902679 240 0.057
single organism catabolic process GO:0044712 228 0.057
Yeast
positive regulation of rna metabolic process GO:0051254 271 0.056
organic cyclic compound catabolic process GO:1901361 168 0.056
positive regulation of cellular biosynthetic process GO:0031328 316 0.055
Human
nicotinamide nucleotide metabolic process GO:0046496 2 0.055
Mouse
organic substance catabolic process GO:1901575 308 0.054
Yeast
developmental growth GO:0048589 280 0.054
pigmentation GO:0043473 75 0.053
response to lipopolysaccharide GO:0032496 4 0.051
organelle fission GO:0048285 340 0.051
cell cell junction organization GO:0045216 55 0.051
columnar cuboidal epithelial cell development GO:0002066 249 0.051
positive regulation of transcription from rna polymerase ii promoter GO:0045944 204 0.050
regulation of transport GO:0051049 181 0.050
Human Mouse
small molecule metabolic process GO:0044281 305 0.050
Human Yeast Mouse
nuclear division GO:0000280 332 0.050
aromatic compound catabolic process GO:0019439 166 0.049
actin cytoskeleton organization GO:0030036 206 0.049
nucleoside phosphate metabolic process GO:0006753 162 0.049
Mouse
intracellular signal transduction GO:0035556 300 0.047
cellular ketone metabolic process GO:0042180 24 0.047
Human
negative regulation of gene expression GO:0010629 387 0.047
programmed cell death GO:0012501 257 0.047
Mouse
epithelial cell development GO:0002064 274 0.047
positive regulation of nucleobase containing compound metabolic process GO:0045935 332 0.046
cell motility GO:0048870 251 0.046
chemotaxis GO:0006935 249 0.046
positive regulation of macromolecule metabolic process GO:0010604 405 0.046
Human
positive regulation of cell communication GO:0010647 250 0.045
Human Mouse
response to oxygen containing compound GO:1901700 200 0.044
Human
organonitrogen compound catabolic process GO:1901565 128 0.044
phagocytosis GO:0006909 215 0.044
cellular amino acid metabolic process GO:0006520 61 0.044
cell proliferation GO:0008283 299 0.043
notch signaling pathway GO:0007219 120 0.043
hindbrain development GO:0030902 2 0.042
mitotic nuclear division GO:0007067 213 0.041
camera type eye development GO:0043010 4 0.041
growth GO:0040007 359 0.040
imaginal disc derived appendage morphogenesis GO:0035114 395 0.040
regulation of programmed cell death GO:0043067 152 0.040
nadh metabolic process GO:0006734 1 0.039
transcription from rna polymerase ii promoter GO:0006366 368 0.038
negative regulation of nucleic acid templated transcription GO:1903507 240 0.038
epidermis development GO:0008544 65 0.037
negative regulation of cell proliferation GO:0008285 69 0.036
embryo development ending in birth or egg hatching GO:0009792 152 0.036
axon development GO:0061564 297 0.036
appendage morphogenesis GO:0035107 397 0.036
vesicle mediated transport GO:0016192 381 0.036
imaginal disc derived appendage development GO:0048737 399 0.035
negative regulation of cell cycle GO:0045786 116 0.035
regionalization GO:0003002 416 0.035
regulation of transcription from rna polymerase ii promoter GO:0006357 378 0.034
single organism biosynthetic process GO:0044711 206 0.034
Human
retina development in camera type eye GO:0060041 4 0.034
cell junction organization GO:0034330 57 0.034
negative regulation of multicellular organismal process GO:0051241 142 0.034
negative regulation of mitotic cell cycle phase transition GO:1901991 103 0.033
glutamate metabolic process GO:0006536 5 0.033
positive regulation of transcription dna templated GO:0045893 266 0.033
nephron development GO:0072006 3 0.033
negative regulation of cellular macromolecule biosynthetic process GO:2000113 267 0.032
cellular nitrogen compound catabolic process GO:0044270 165 0.032
epithelial cell migration GO:0010631 148 0.032
cell migration GO:0016477 238 0.032
response to bacterium GO:0009617 198 0.032
regulation of intracellular signal transduction GO:1902531 236 0.031
response to alcohol GO:0097305 95 0.031
kidney development GO:0001822 3 0.031
wing disc morphogenesis GO:0007472 344 0.031
detection of light stimulus GO:0009583 58 0.030
response to light stimulus GO:0009416 124 0.030
organic acid metabolic process GO:0006082 103 0.030
Yeast
regulation of cellular ketone metabolic process GO:0010565 3 0.029
Human
positive regulation of nitrogen compound metabolic process GO:0051173 354 0.029
catabolic process GO:0009056 409 0.029
Yeast
carboxylic acid metabolic process GO:0019752 92 0.029
Yeast
sensory perception GO:0007600 196 0.028
regulation of apoptotic process GO:0042981 130 0.028
energy derivation by oxidation of organic compounds GO:0015980 32 0.028
Human
regulation of phosphate metabolic process GO:0019220 210 0.028
meiotic nuclear division GO:0007126 151 0.028
negative regulation of cell cycle process GO:0010948 109 0.028
imaginal disc derived wing morphogenesis GO:0007476 337 0.027
axonogenesis GO:0007409 290 0.027
cell adhesion GO:0007155 136 0.027
actin filament based process GO:0030029 220 0.027
positive regulation of signaling GO:0023056 243 0.027
Human Mouse
positive regulation of nucleic acid templated transcription GO:1903508 266 0.027
nucleobase containing small molecule metabolic process GO:0055086 174 0.027
Mouse
oxoacid metabolic process GO:0043436 103 0.026
Yeast
morphogenesis of an epithelium GO:0002009 276 0.026
regulation of cell development GO:0060284 215 0.026
amine metabolic process GO:0009308 12 0.026
negative regulation of transcription dna templated GO:0045892 237 0.026
positive regulation of cell death GO:0010942 69 0.025
heterocycle catabolic process GO:0046700 166 0.025
regulation of cellular localization GO:0060341 136 0.024
Human Mouse
axon guidance GO:0007411 233 0.024
carbohydrate biosynthetic process GO:0016051 17 0.024
Human
stem cell proliferation GO:0072089 88 0.024
oxidation reduction process GO:0055114 123 0.024
Human
cellular protein modification process GO:0006464 438 0.024
purine nucleotide catabolic process GO:0006195 109 0.023
columnar cuboidal epithelial cell differentiation GO:0002065 256 0.023
regulation of cell cycle phase transition GO:1901987 130 0.023
negative regulation of cellular biosynthetic process GO:0031327 277 0.023
Human
hair cell differentiation GO:0035315 47 0.023
response to radiation GO:0009314 155 0.023
cellular response to dna damage stimulus GO:0006974 223 0.023
cell junction assembly GO:0034329 42 0.023
dorsal ventral pattern formation GO:0009953 133 0.023
regulation of notch signaling pathway GO:0008593 100 0.023
meiotic cell cycle GO:0051321 171 0.023
ras protein signal transduction GO:0007265 88 0.023
forebrain development GO:0030900 2 0.023
cellular catabolic process GO:0044248 372 0.023
negative regulation of nucleobase containing compound metabolic process GO:0045934 261 0.022
positive regulation of gene expression GO:0010628 290 0.022
rna localization GO:0006403 115 0.022
detection of stimulus GO:0051606 156 0.022
Human
brain development GO:0007420 120 0.022
negative regulation of macromolecule biosynthetic process GO:0010558 270 0.022
tissue morphogenesis GO:0048729 297 0.022
telencephalon development GO:0021537 2 0.022
negative regulation of mitotic cell cycle GO:0045930 109 0.022
nucleobase containing compound catabolic process GO:0034655 165 0.022
regulation of protein metabolic process GO:0051246 256 0.022
regulation of oocyte development GO:0060281 27 0.022
body morphogenesis GO:0010171 2 0.021
post embryonic appendage morphogenesis GO:0035120 385 0.021
death GO:0016265 284 0.021
Mouse
protein modification process GO:0036211 438 0.021
negative regulation of biosynthetic process GO:0009890 277 0.021
Human
ameboidal type cell migration GO:0001667 151 0.021
epidermal cell differentiation GO:0009913 51 0.020
positive regulation of multicellular organismal process GO:0051240 143 0.020
central nervous system development GO:0007417 201 0.020
regulation of mitotic cell cycle GO:0007346 190 0.020
single organism behavior GO:0044708 391 0.020
response to other organism GO:0051707 293 0.020
sensory organ morphogenesis GO:0090596 260 0.020
negative regulation of nitrogen compound metabolic process GO:0051172 265 0.020
response to monosaccharide GO:0034284 4 0.020
Human
homeostatic process GO:0042592 199 0.020
Human Mouse
apoptotic process GO:0006915 159 0.020
Mouse
negative regulation of cell differentiation GO:0045596 143 0.020
regulation of cell differentiation GO:0045595 302 0.020
dna metabolic process GO:0006259 227 0.020
phosphorylation GO:0016310 294 0.020
positive regulation of developmental process GO:0051094 143 0.020
positive regulation of cell migration GO:0030335 2 0.019
positive regulation of cellular protein metabolic process GO:0032270 118 0.019
synaptic target recognition GO:0008039 45 0.019
cellular component assembly involved in morphogenesis GO:0010927 151 0.019
skin development GO:0043588 65 0.019
taxis GO:0042330 304 0.019
positive regulation of phosphorus metabolic process GO:0010562 139 0.019
regulation of phosphorus metabolic process GO:0051174 210 0.019
metal ion transport GO:0030001 74 0.019
Mouse
posttranscriptional gene silencing by rna GO:0035194 45 0.019
epithelial tube morphogenesis GO:0060562 88 0.019
regulation of epithelial cell differentiation GO:0030856 4 0.018
mitotic spindle organization GO:0007052 220 0.018
heart morphogenesis GO:0003007 32 0.018
positive regulation of phosphate metabolic process GO:0045937 139 0.018
gliogenesis GO:0042063 80 0.018
nephron epithelium development GO:0072009 3 0.018
neuronal action potential GO:0019228 10 0.018
regulation of cell proliferation GO:0042127 163 0.018
open tracheal system development GO:0007424 204 0.018
purine ribonucleotide metabolic process GO:0009150 145 0.018
positive regulation of cellular component biogenesis GO:0044089 80 0.018
smoothened signaling pathway GO:0007224 49 0.018
small gtpase mediated signal transduction GO:0007264 88 0.018
neuroblast proliferation GO:0007405 74 0.017
acetylcholine metabolic process GO:0008291 2 0.017
nitrogen compound transport GO:0071705 85 0.017
Human Mouse
regulation of localization GO:0032879 275 0.017
Human Mouse
alpha amino acid metabolic process GO:1901605 20 0.017
choline catabolic process GO:0042426 1 0.017
positive regulation of catabolic process GO:0009896 105 0.017
cellular macromolecule catabolic process GO:0044265 136 0.017
ribonucleotide catabolic process GO:0009261 109 0.017
single organism cell adhesion GO:0098602 47 0.017
detection of stimulus involved in sensory perception GO:0050906 92 0.017
response to organic cyclic compound GO:0014070 89 0.017
carbohydrate derivative metabolic process GO:1901135 217 0.017
Human Yeast Mouse
regulation of gene expression epigenetic GO:0040029 128 0.017
positive regulation of cell motility GO:2000147 3 0.016
purine containing compound catabolic process GO:0072523 112 0.016
regulation of cellular amine metabolic process GO:0033238 3 0.016
posttranscriptional regulation of gene expression GO:0010608 145 0.016
cell cell junction assembly GO:0007043 38 0.016
detection of external stimulus GO:0009581 66 0.016
memory GO:0007613 94 0.016
ribose phosphate metabolic process GO:0019693 145 0.016
gene silencing by rna GO:0031047 57 0.016
cell division GO:0051301 248 0.016
neuron projection guidance GO:0097485 241 0.016
heart development GO:0007507 82 0.016
response to endogenous stimulus GO:0009719 119 0.016
carbohydrate metabolic process GO:0005975 82 0.016
regulation of mapk cascade GO:0043408 92 0.015
cellular response to organic substance GO:0071310 132 0.015
chromosome organization GO:0051276 360 0.015
positive regulation of biosynthetic process GO:0009891 316 0.015
Human
establishment of blood nerve barrier GO:0008065 2 0.015
ribonucleotide metabolic process GO:0009259 145 0.015
epithelium migration GO:0090132 148 0.015
imaginal disc derived wing hair organization GO:0035317 45 0.015
wound healing GO:0042060 75 0.015
negative regulation of cell cycle phase transition GO:1901988 103 0.015
pyridine containing compound metabolic process GO:0072524 3 0.015
Mouse
non sensory hair organization GO:0035316 47 0.015
imaginal disc pattern formation GO:0007447 91 0.015
regulation of organelle organization GO:0033043 196 0.015
cellular response to chemical stimulus GO:0070887 199 0.014
organophosphate metabolic process GO:0019637 195 0.014
Human Yeast Mouse
nucleobase containing compound transport GO:0015931 56 0.014
positive regulation of programmed cell death GO:0043068 62 0.014
regulation of steroid metabolic process GO:0019218 2 0.014
chaeta development GO:0022416 97 0.014
positive regulation of response to stimulus GO:0048584 323 0.014
positive regulation of transport GO:0051050 92 0.014
Human Mouse
anatomical structure homeostasis GO:0060249 97 0.014
positive regulation of lipid metabolic process GO:0045834 4 0.014
deactivation of rhodopsin mediated signaling GO:0016059 17 0.014
acyl coa metabolic process GO:0006637 3 0.014
positive regulation of organelle organization GO:0010638 65 0.014
nucleoside phosphate catabolic process GO:1901292 110 0.014
response to organic substance GO:0010033 284 0.014
Human
regulation of mitotic cell cycle phase transition GO:1901990 130 0.014
response to hexose GO:0009746 3 0.014
Human
larval development GO:0002164 104 0.014
regulation of cellular protein metabolic process GO:0032268 243 0.014
spindle organization GO:0007051 253 0.014
regulation of hydrolase activity GO:0051336 97 0.014
eye morphogenesis GO:0048592 260 0.014
cuticle development GO:0042335 86 0.014
regulation of ras protein signal transduction GO:0046578 93 0.014
positive regulation of signal transduction GO:0009967 223 0.013
negative regulation of developmental process GO:0051093 201 0.013
hematopoietic or lymphoid organ development GO:0048534 57 0.013
regulation of microtubule cytoskeleton organization GO:0070507 41 0.013
tissue migration GO:0090130 155 0.013
detection of abiotic stimulus GO:0009582 66 0.013
embryonic development via the syncytial blastoderm GO:0001700 148 0.013
purine nucleotide metabolic process GO:0006163 146 0.013
heart contraction GO:0060047 26 0.013
g protein coupled receptor signaling pathway GO:0007186 136 0.013
stem cell division GO:0017145 69 0.013
cell fate determination GO:0001709 91 0.013
regulation of small gtpase mediated signal transduction GO:0051056 93 0.013
regulation of catalytic activity GO:0050790 185 0.013
cellular amine metabolic process GO:0044106 12 0.013
positive regulation of cellular catabolic process GO:0031331 95 0.013
cellular response to ethanol GO:0071361 4 0.013
choline metabolic process GO:0019695 1 0.013
regulation of epidermal cell differentiation GO:0045604 3 0.013
intracellular transport GO:0046907 228 0.012
regulation of cellular amino acid metabolic process GO:0006521 0 0.012
negative regulation of cell death GO:0060548 81 0.012
negative regulation of transcription from rna polymerase ii promoter GO:0000122 119 0.012
chromosome segregation GO:0007059 157 0.012
neural precursor cell proliferation GO:0061351 75 0.012
organic hydroxy compound biosynthetic process GO:1901617 21 0.012
negative regulation of rna metabolic process GO:0051253 251 0.012
positive regulation of rna biosynthetic process GO:1902680 266 0.012
positive regulation of molecular function GO:0044093 136 0.012
regulation of embryonic development GO:0045995 68 0.012
purine containing compound metabolic process GO:0072521 155 0.012
cell maturation GO:0048469 144 0.012
connective tissue development GO:0061448 3 0.012
positive regulation of purine nucleotide catabolic process GO:0033123 46 0.012
positive regulation of protein metabolic process GO:0051247 128 0.012
regulation of phosphorylation GO:0042325 147 0.012
kidney morphogenesis GO:0060993 3 0.012
stem cell maintenance GO:0019827 67 0.012
regulation of membrane potential GO:0042391 35 0.012
photoreceptor cell differentiation GO:0046530 170 0.012
negative regulation of growth GO:0045926 84 0.012
female meiosis chromosome segregation GO:0016321 33 0.012
hormone catabolic process GO:0042447 3 0.012
endomembrane system organization GO:0010256 119 0.012
kidney epithelium development GO:0072073 3 0.012
regulation of purine nucleotide metabolic process GO:1900542 62 0.012
ethanolamine containing compound metabolic process GO:0042439 4 0.012
cell cycle phase transition GO:0044770 140 0.012
secretion GO:0046903 109 0.012
Human Mouse Rat
acetylcholine catabolic process GO:0006581 1 0.011
dna replication GO:0006260 48 0.011
cell death GO:0008219 279 0.011
Mouse
regulation of cytoskeleton organization GO:0051493 89 0.011
adult behavior GO:0030534 137 0.011
mapk cascade GO:0000165 107 0.011
pyruvate metabolic process GO:0006090 7 0.011
Yeast
regulation of neuron differentiation GO:0045664 103 0.011
anterior posterior pattern specification GO:0009952 136 0.011
nephron tubule development GO:0072080 3 0.011
regulation of glial cell differentiation GO:0045685 1 0.011
purine ribonucleotide catabolic process GO:0009154 109 0.011
response to glucose GO:0009749 2 0.011
Human
developmental maturation GO:0021700 172 0.011
regulation of meiosis GO:0040020 3 0.011
nucleotide metabolic process GO:0009117 161 0.011
Mouse
response to biotic stimulus GO:0009607 294 0.011
regulation of cell junction assembly GO:1901888 2 0.011
nucleotide catabolic process GO:0009166 109 0.011
protein phosphorylation GO:0006468 169 0.011
cell aging GO:0007569 2 0.011
regulation of protein complex disassembly GO:0043244 29 0.011
long term memory GO:0007616 62 0.011
synapse organization GO:0050808 196 0.011
proteolysis GO:0006508 192 0.011
cell fate commitment involved in pattern specification GO:0060581 31 0.011
cell growth GO:0016049 108 0.011
respiratory system development GO:0060541 213 0.011
tricarboxylic acid metabolic process GO:0072350 1 0.011
stem cell differentiation GO:0048863 117 0.010
regulation of response to dna damage stimulus GO:2001020 23 0.010
cellular homeostasis GO:0019725 80 0.010
Mouse
glial cell proliferation GO:0014009 13 0.010
positive regulation of intracellular signal transduction GO:1902533 116 0.010
regulation of microtubule polymerization or depolymerization GO:0031110 27 0.010
regulation of gene silencing GO:0060968 63 0.010
response to nutrient levels GO:0031667 114 0.010
compound eye development GO:0048749 307 0.010
oocyte axis specification GO:0007309 108 0.010
immune system development GO:0002520 57 0.010
neuronal stem cell maintenance GO:0097150 4 0.010
maintenance of imaginal disc derived wing hair orientation GO:0035321 3 0.010
regulation of catabolic process GO:0009894 170 0.010
positive regulation of cell differentiation GO:0045597 64 0.010
organelle assembly GO:0070925 198 0.010

Hex-A disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in fly and predicted with the fly functional network.

Disease DO term ID Size Probability Func Analog Org
disease of anatomical entity DOID:7 0 0.035
disease of metabolism DOID:0014667 0 0.018
Human
carbohydrate metabolism disease DOID:0050013 0 0.018
Human
glucose metabolism disease DOID:4194 0 0.018
Human
acquired metabolic disease DOID:0060158 0 0.018
Human
nervous system disease DOID:863 0 0.016
musculoskeletal system disease DOID:17 0 0.016