Drosophila melanogaster

102 known processes

Cerk (Dmel_CG16708)

Ceramide kinase

(Aliases: DCERK,Dmel\CG16708,dcerk,CG16708)

Cerk biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
protein modification process GO:0036211 438 0.083
positive regulation of nitrogen compound metabolic process GO:0051173 354 0.081
intracellular signal transduction GO:0035556 300 0.073
synapse organization GO:0050808 196 0.073
wing disc morphogenesis GO:0007472 344 0.069
regulation of multicellular organismal development GO:2000026 414 0.067
negative regulation of nitrogen compound metabolic process GO:0051172 265 0.063
protein localization GO:0008104 284 0.057
ras protein signal transduction GO:0007265 88 0.055
imaginal disc derived appendage morphogenesis GO:0035114 395 0.052
cellular protein modification process GO:0006464 438 0.050
tube morphogenesis GO:0035239 191 0.049
response to radiation GO:0009314 155 0.048
appendage morphogenesis GO:0035107 397 0.047
post embryonic appendage morphogenesis GO:0035120 385 0.043
regulation of synapse assembly GO:0051963 94 0.042
endocytosis GO:0006897 310 0.042
developmental growth GO:0048589 280 0.041
compound eye development GO:0048749 307 0.040
organophosphate metabolic process GO:0019637 195 0.040
regulation of protein metabolic process GO:0051246 256 0.040
nuclear division GO:0000280 332 0.039
detection of stimulus GO:0051606 156 0.038
lipid metabolic process GO:0006629 121 0.038
detection of light stimulus GO:0009583 58 0.038
small molecule metabolic process GO:0044281 305 0.037
positive regulation of transcription dna templated GO:0045893 266 0.036
transcription from rna polymerase ii promoter GO:0006366 368 0.036
cellular macromolecule localization GO:0070727 220 0.036
eye morphogenesis GO:0048592 260 0.035
positive regulation of cellular catabolic process GO:0031331 95 0.035
protein modification by small protein conjugation or removal GO:0070647 106 0.035
regulation of intracellular signal transduction GO:1902531 236 0.035
phagocytosis GO:0006909 215 0.035
programmed cell death GO:0012501 257 0.034
response to abiotic stimulus GO:0009628 341 0.034
sensory organ morphogenesis GO:0090596 260 0.034
negative regulation of cellular macromolecule biosynthetic process GO:2000113 267 0.033
negative regulation of cellular metabolic process GO:0031324 382 0.033
tissue morphogenesis GO:0048729 297 0.033
regulation of synapse structure and activity GO:0050803 128 0.033
positive regulation of rna biosynthetic process GO:1902680 266 0.033
organonitrogen compound metabolic process GO:1901564 318 0.033
synapse assembly GO:0007416 143 0.033
phosphorylation GO:0016310 294 0.033
positive regulation of ras gtpase activity GO:0032320 36 0.033
catabolic process GO:0009056 409 0.032
negative regulation of cellular biosynthetic process GO:0031327 277 0.032
positive regulation of nucleobase containing compound metabolic process GO:0045935 332 0.032
positive regulation of rna metabolic process GO:0051254 271 0.032
aromatic compound catabolic process GO:0019439 166 0.032
negative regulation of response to stimulus GO:0048585 258 0.032
negative regulation of cell cycle GO:0045786 116 0.031
positive regulation of nucleic acid templated transcription GO:1903508 266 0.031
regulation of small gtpase mediated signal transduction GO:0051056 93 0.031
death GO:0016265 284 0.031
imaginal disc derived appendage development GO:0048737 399 0.031
regulation of nervous system development GO:0051960 248 0.031
organic substance catabolic process GO:1901575 308 0.031
establishment of localization in cell GO:0051649 402 0.030
nucleobase containing small molecule metabolic process GO:0055086 174 0.030
synaptic growth at neuromuscular junction GO:0051124 119 0.030
protein transport GO:0015031 155 0.030
proteolysis GO:0006508 192 0.030
spermatogenesis GO:0007283 200 0.029
organophosphate catabolic process GO:0046434 112 0.029
histolysis GO:0007559 102 0.029
nucleobase containing compound catabolic process GO:0034655 165 0.028
positive regulation of cellular biosynthetic process GO:0031328 316 0.028
neurological system process GO:0050877 358 0.028
regulation of transport GO:0051049 181 0.028
regulation of transcription from rna polymerase ii promoter GO:0006357 378 0.028
g protein coupled receptor signaling pathway GO:0007186 136 0.028
negative regulation of nucleobase containing compound metabolic process GO:0045934 261 0.028
organelle localization GO:0051640 148 0.027
glycerolipid metabolic process GO:0046486 34 0.027
organelle fission GO:0048285 340 0.027
cation transport GO:0006812 110 0.027
regulation of cellular catabolic process GO:0031329 157 0.027
negative regulation of gene expression GO:0010629 387 0.026
heterocycle catabolic process GO:0046700 166 0.026
regulation of catabolic process GO:0009894 170 0.026
regulation of cell development GO:0060284 215 0.025
negative regulation of rna metabolic process GO:0051253 251 0.025
positive regulation of macromolecule metabolic process GO:0010604 405 0.025
nucleoside phosphate metabolic process GO:0006753 162 0.025
digestive tract morphogenesis GO:0048546 127 0.025
small gtpase mediated signal transduction GO:0007264 88 0.024
positive regulation of gene expression GO:0010628 290 0.024
vesicle mediated transport GO:0016192 381 0.024
ribonucleoside catabolic process GO:0042454 112 0.024
positive regulation of purine nucleotide catabolic process GO:0033123 46 0.024
regulation of ras protein signal transduction GO:0046578 93 0.024
nucleoside triphosphate catabolic process GO:0009143 108 0.024
positive regulation of transcription from rna polymerase ii promoter GO:0045944 204 0.024
endomembrane system organization GO:0010256 119 0.024
detection of abiotic stimulus GO:0009582 66 0.024
regulation of cellular localization GO:0060341 136 0.023
nucleotide metabolic process GO:0009117 161 0.023
defense response to other organism GO:0098542 225 0.023
appendage development GO:0048736 401 0.023
regulation of purine nucleotide metabolic process GO:1900542 62 0.023
imaginal disc derived wing morphogenesis GO:0007476 337 0.023
positive regulation of nucleotide catabolic process GO:0030813 46 0.023
regulation of growth GO:0040008 233 0.023
developmental programmed cell death GO:0010623 138 0.023
positive regulation of catabolic process GO:0009896 105 0.023
negative regulation of cell cycle process GO:0010948 109 0.023
intracellular transport GO:0046907 228 0.022
regulation of phosphate metabolic process GO:0019220 210 0.022
defense response GO:0006952 300 0.022
purine nucleoside metabolic process GO:0042278 127 0.022
macromolecule catabolic process GO:0009057 161 0.022
purine nucleotide catabolic process GO:0006195 109 0.022
growth GO:0040007 359 0.022
purine containing compound metabolic process GO:0072521 155 0.022
compound eye morphogenesis GO:0001745 249 0.022
compound eye photoreceptor cell differentiation GO:0001751 140 0.022
cellular amine metabolic process GO:0044106 12 0.022
regulation of cellular protein metabolic process GO:0032268 243 0.022
negative regulation of macromolecule biosynthetic process GO:0010558 270 0.022
purine ribonucleoside metabolic process GO:0046128 127 0.022
purine ribonucleotide metabolic process GO:0009150 145 0.021
regulation of mitotic cell cycle GO:0007346 190 0.021
peptidyl amino acid modification GO:0018193 105 0.021
nucleoside metabolic process GO:0009116 127 0.021
central nervous system development GO:0007417 201 0.021
regulation of cell death GO:0010941 173 0.021
positive regulation of biosynthetic process GO:0009891 316 0.021
negative regulation of developmental process GO:0051093 201 0.021
regulation of cell differentiation GO:0045595 302 0.021
oocyte differentiation GO:0009994 145 0.021
negative regulation of nucleic acid templated transcription GO:1903507 240 0.021
glycosyl compound catabolic process GO:1901658 112 0.021
ribonucleoside metabolic process GO:0009119 127 0.021
organic substance transport GO:0071702 257 0.021
purine ribonucleoside triphosphate catabolic process GO:0009207 108 0.021
positive regulation of signaling GO:0023056 243 0.021
negative regulation of mitotic cell cycle GO:0045930 109 0.020
regulation of cell cycle GO:0051726 291 0.020
carbohydrate derivative metabolic process GO:1901135 217 0.020
regulation of response to external stimulus GO:0032101 115 0.020
purine nucleoside catabolic process GO:0006152 112 0.020
tissue death GO:0016271 102 0.020
eye development GO:0001654 323 0.020
purine nucleoside triphosphate catabolic process GO:0009146 108 0.020
establishment of protein localization GO:0045184 163 0.020
purine nucleotide metabolic process GO:0006163 146 0.020
regulation of cell cycle phase transition GO:1901987 130 0.020
protein ubiquitination GO:0016567 70 0.020
regulation of molecular function GO:0065009 217 0.020
positive regulation of cell communication GO:0010647 250 0.020
eye photoreceptor cell differentiation GO:0001754 145 0.020
regulation of cellular amine metabolic process GO:0033238 3 0.020
cellular macromolecule catabolic process GO:0044265 136 0.019
tube development GO:0035295 244 0.019
photoreceptor cell development GO:0042461 96 0.019
purine ribonucleoside triphosphate metabolic process GO:0009205 119 0.019
organelle assembly GO:0070925 198 0.019
purine ribonucleoside catabolic process GO:0046130 112 0.019
regulation of cellular component biogenesis GO:0044087 201 0.019
regulation of defense response GO:0031347 102 0.019
single organism biosynthetic process GO:0044711 206 0.019
epithelial cell development GO:0002064 274 0.019
cellular protein localization GO:0034613 160 0.019
regulation of cellular amino acid metabolic process GO:0006521 0 0.019
regulation of hydrolase activity GO:0051336 97 0.019
regulation of ras gtpase activity GO:0032318 38 0.019
spermatid differentiation GO:0048515 114 0.019
nucleoside catabolic process GO:0009164 112 0.019
negative regulation of signal transduction GO:0009968 206 0.019
positive regulation of macromolecule biosynthetic process GO:0010557 283 0.019
purine containing compound catabolic process GO:0072523 112 0.019
actin cytoskeleton organization GO:0030036 206 0.018
glycosyl compound metabolic process GO:1901657 127 0.018
negative regulation of protein metabolic process GO:0051248 85 0.018
positive regulation of multicellular organismal process GO:0051240 143 0.018
salivary gland cell autophagic cell death GO:0035071 83 0.018
single organism behavior GO:0044708 391 0.018
single organism intracellular transport GO:1902582 207 0.018
cell motility GO:0048870 251 0.018
nucleus organization GO:0006997 45 0.018
ribose phosphate metabolic process GO:0019693 145 0.018
digestive system development GO:0055123 149 0.018
establishment or maintenance of cytoskeleton polarity GO:0030952 44 0.018
cell cell signaling involved in cell fate commitment GO:0045168 210 0.018
eye photoreceptor cell development GO:0042462 81 0.018
single organism membrane fusion GO:0044801 42 0.018
gtp catabolic process GO:0006184 72 0.018
regulation of developmental growth GO:0048638 174 0.018
negative regulation of cellular protein metabolic process GO:0032269 85 0.018
secretory granule organization GO:0033363 6 0.017
protein modification by small protein conjugation GO:0032446 79 0.017
regulation of gtp catabolic process GO:0033124 44 0.017
response to organic substance GO:0010033 284 0.017
mitotic nuclear division GO:0007067 213 0.017
nucleoside phosphate catabolic process GO:1901292 110 0.017
regulation of programmed cell death GO:0043067 152 0.017
ion transport GO:0006811 145 0.017
regulation of cellular component size GO:0032535 98 0.017
regulation of synapse organization GO:0050807 110 0.017
long term memory GO:0007616 62 0.017
response to light stimulus GO:0009416 124 0.017
regulation of organelle organization GO:0033043 196 0.017
rho protein signal transduction GO:0007266 14 0.017
guanosine containing compound metabolic process GO:1901068 74 0.017
regulation of cellular ketone metabolic process GO:0010565 3 0.017
establishment or maintenance of microtubule cytoskeleton polarity GO:0030951 41 0.017
positive regulation of cellular amino acid metabolic process GO:0045764 0 0.017
photoreceptor cell differentiation GO:0046530 170 0.017
regulation of response to stress GO:0080134 200 0.017
negative regulation of rna biosynthetic process GO:1902679 240 0.016
regulation of notch signaling pathway GO:0008593 100 0.016
hindbrain development GO:0030902 2 0.016
regulation of protein modification process GO:0031399 112 0.016
negative regulation of cell communication GO:0010648 223 0.016
open tracheal system development GO:0007424 204 0.016
signal transduction by phosphorylation GO:0023014 107 0.016
immune system process GO:0002376 347 0.016
organonitrogen compound catabolic process GO:1901565 128 0.016
positive regulation of cellular component organization GO:0051130 156 0.016
autophagic cell death GO:0048102 83 0.016
regulation of localization GO:0032879 275 0.016
organic cyclic compound catabolic process GO:1901361 168 0.016
lateral inhibition GO:0046331 206 0.016
response to wounding GO:0009611 94 0.016
positive regulation of transport GO:0051050 92 0.016
mapk cascade GO:0000165 107 0.016
chromatin organization GO:0006325 207 0.016
dephosphorylation GO:0016311 51 0.016
regulation of synaptic transmission GO:0050804 69 0.015
positive regulation of nucleoside metabolic process GO:0045979 47 0.015
single organism catabolic process GO:0044712 228 0.015
multi multicellular organism process GO:0044706 123 0.015
nucleotide catabolic process GO:0009166 109 0.015
actin filament based process GO:0030029 220 0.015
negative regulation of cell differentiation GO:0045596 143 0.015
regulation of immune system process GO:0002682 176 0.015
body morphogenesis GO:0010171 2 0.015
positive regulation of signal transduction GO:0009967 223 0.015
synaptic transmission GO:0007268 288 0.015
regulation of neurogenesis GO:0050767 158 0.015
actin filament organization GO:0007015 126 0.015
negative regulation of erbb signaling pathway GO:1901185 29 0.015
response to temperature stimulus GO:0009266 106 0.015
positive regulation of exocytosis GO:0045921 4 0.015
cellular amino acid metabolic process GO:0006520 61 0.015
ribonucleotide metabolic process GO:0009259 145 0.015
exocrine system development GO:0035272 162 0.015
chromatin modification GO:0016568 147 0.014
cellular response to dna damage stimulus GO:0006974 223 0.014
response to other organism GO:0051707 293 0.014
purine nucleoside triphosphate metabolic process GO:0009144 119 0.014
regulation of gene expression epigenetic GO:0040029 128 0.014
ribonucleoside triphosphate metabolic process GO:0009199 119 0.014
regulation of phosphorylation GO:0042325 147 0.014
meiotic cell cycle GO:0051321 171 0.014
regulation of purine nucleotide catabolic process GO:0033121 48 0.014
positive regulation of purine nucleotide metabolic process GO:1900544 55 0.014
eye pigment granule organization GO:0008057 12 0.014
regulation of gtpase activity GO:0043087 44 0.014
positive regulation of response to stimulus GO:0048584 323 0.014
dendrite development GO:0016358 204 0.014
carboxylic acid metabolic process GO:0019752 92 0.014
response to lipopolysaccharide GO:0032496 4 0.014
single organism membrane organization GO:0044802 93 0.014
organelle fusion GO:0048284 46 0.014
positive regulation of hydrolase activity GO:0051345 78 0.014
phototransduction GO:0007602 52 0.014
regulation of cell cycle process GO:0010564 181 0.014
ribonucleoside triphosphate catabolic process GO:0009203 108 0.014
oxoacid metabolic process GO:0043436 103 0.014
regulation of mapk cascade GO:0043408 92 0.014
vesicle organization GO:0016050 44 0.013
regulation of catalytic activity GO:0050790 185 0.013
positive regulation of phosphate metabolic process GO:0045937 139 0.013
cell proliferation GO:0008283 299 0.013
regionalization GO:0003002 416 0.013
regulation of phosphorus metabolic process GO:0051174 210 0.013
telencephalon development GO:0021537 2 0.013
negative regulation of biosynthetic process GO:0009890 277 0.013
guanosine containing compound catabolic process GO:1901069 74 0.013
salivary gland development GO:0007431 162 0.013
vesicle localization GO:0051648 55 0.013
homeostatic process GO:0042592 199 0.013
regulation of apoptotic process GO:0042981 130 0.013
protein targeting GO:0006605 64 0.013
salivary gland histolysis GO:0035070 88 0.013
secretion GO:0046903 109 0.013
mrna processing GO:0006397 104 0.013
rna processing GO:0006396 147 0.013
oocyte construction GO:0007308 112 0.013
skin development GO:0043588 65 0.013
cellular catabolic process GO:0044248 372 0.013
negative regulation of multicellular organismal process GO:0051241 142 0.013
axon development GO:0061564 297 0.013
segmentation GO:0035282 207 0.013
negative regulation of intracellular signal transduction GO:1902532 57 0.013
proteolysis involved in cellular protein catabolic process GO:0051603 83 0.013
cellular nitrogen compound catabolic process GO:0044270 165 0.013
glycerophospholipid metabolic process GO:0006650 23 0.013
cellular protein catabolic process GO:0044257 83 0.012
nucleoside triphosphate metabolic process GO:0009141 120 0.012
secretion by cell GO:0032940 101 0.012
response to nutrient levels GO:0031667 114 0.012
regulation of macroautophagy GO:0016241 15 0.012
chromosome organization GO:0051276 360 0.012
negative regulation of organelle organization GO:0010639 56 0.012
notch signaling pathway GO:0007219 120 0.012
digestive tract development GO:0048565 149 0.012
ribonucleotide catabolic process GO:0009261 109 0.012
protein processing GO:0016485 68 0.012
negative regulation of signaling GO:0023057 219 0.012
positive regulation of cell death GO:0010942 69 0.012
rna 3 end processing GO:0031123 45 0.012
negative regulation of transcription dna templated GO:0045892 237 0.012
positive regulation of apoptotic process GO:0043065 47 0.012
gtp metabolic process GO:0046039 72 0.012
regulation of mrna 3 end processing GO:0031440 7 0.012
amine metabolic process GO:0009308 12 0.012
cellular response to starvation GO:0009267 61 0.012
response to oxygen containing compound GO:1901700 200 0.012
rhabdomere development GO:0042052 38 0.012
acid secretion GO:0046717 1 0.012
cytoplasmic transport GO:0016482 130 0.012
regulation of proteolysis GO:0030162 87 0.012
embryonic pattern specification GO:0009880 174 0.011
negative regulation of erk1 and erk2 cascade GO:0070373 3 0.011
response to starvation GO:0042594 97 0.011
protein phosphorylation GO:0006468 169 0.011
regulation of nucleotide catabolic process GO:0030811 48 0.011
learning or memory GO:0007611 141 0.011
macroautophagy GO:0016236 42 0.011
asymmetric protein localization GO:0008105 33 0.011
positive regulation of gtpase activity GO:0043547 43 0.011
embryonic morphogenesis GO:0048598 206 0.011
dorsal ventral pattern formation GO:0009953 133 0.011
cell cycle phase transition GO:0044770 140 0.011
peripheral nervous system development GO:0007422 52 0.011
response to organophosphorus GO:0046683 2 0.011
regulation of response to wounding GO:1903034 19 0.011
cell death GO:0008219 279 0.011
male gamete generation GO:0048232 201 0.011
regulation of synaptic growth at neuromuscular junction GO:0008582 89 0.011
purine ribonucleotide catabolic process GO:0009154 109 0.011
cellular lipid metabolic process GO:0044255 83 0.011
female meiosis chromosome segregation GO:0016321 33 0.011
positive regulation of gtp catabolic process GO:0033126 43 0.011
regulation of epithelial cell differentiation GO:0030856 4 0.011
regulation of cell shape GO:0008360 113 0.011
response to extracellular stimulus GO:0009991 116 0.011
detection of external stimulus GO:0009581 66 0.011
localization of cell GO:0051674 257 0.011
positive regulation of nucleotide metabolic process GO:0045981 55 0.011
regulation of anatomical structure size GO:0090066 163 0.011
gastrulation with mouth forming first GO:0001703 36 0.011
single organism cellular localization GO:1902580 180 0.011
rna interference GO:0016246 27 0.011
autophagic vacuole fusion GO:0000046 15 0.011
regulation of organ morphogenesis GO:2000027 78 0.011
negative regulation of molecular function GO:0044092 51 0.011
axonogenesis GO:0007409 290 0.010
gland morphogenesis GO:0022612 145 0.010
negative regulation of nervous system development GO:0051961 92 0.010
modification dependent protein catabolic process GO:0019941 78 0.010
detection of visible light GO:0009584 38 0.010
deactivation of rhodopsin mediated signaling GO:0016059 17 0.010
microtubule cytoskeleton organization involved in mitosis GO:1902850 52 0.010
establishment of planar polarity GO:0001736 87 0.010
intracellular protein transport GO:0006886 104 0.010
cognition GO:0050890 141 0.010
negative regulation of programmed cell death GO:0043069 72 0.010
ovarian follicle cell development GO:0030707 248 0.010
negative regulation of cellular component organization GO:0051129 108 0.010
organelle membrane fusion GO:0090174 16 0.010
locomotory behavior GO:0007626 176 0.010
dendrite morphogenesis GO:0048813 199 0.010
carbohydrate derivative catabolic process GO:1901136 118 0.010
chaeta morphogenesis GO:0008407 42 0.010
negative regulation of phosphate metabolic process GO:0045936 45 0.010
positive regulation of intracellular signal transduction GO:1902533 116 0.010
positive regulation of cell motility GO:2000147 3 0.010

Cerk disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in fly and predicted with the fly functional network.

Disease DO term ID Size Probability Func Analog Org
disease of anatomical entity DOID:7 0 0.022
nervous system disease DOID:863 0 0.015
sensory system disease DOID:0050155 0 0.012
eye and adnexa disease DOID:1492 0 0.012
eye disease DOID:5614 0 0.012
disease of metabolism DOID:0014667 0 0.011
inherited metabolic disorder DOID:655 0 0.011