Drosophila melanogaster

0 known processes

HP5 (Dmel_CG1745)

Heterochromatin protein 5

(Aliases: CG1745,Dmel\CG1745)

HP5 biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
chromosome organization GO:0051276 360 0.412
chromatin assembly GO:0031497 48 0.206
negative regulation of cellular metabolic process GO:0031324 382 0.203
negative regulation of nucleic acid templated transcription GO:1903507 240 0.140
regulation of phosphate metabolic process GO:0019220 210 0.109
imaginal disc derived appendage morphogenesis GO:0035114 395 0.094
negative regulation of gene expression GO:0010629 387 0.090
chromatin assembly or disassembly GO:0006333 52 0.080
dna metabolic process GO:0006259 227 0.077
negative regulation of transcription dna templated GO:0045892 237 0.076
organelle fission GO:0048285 340 0.074
mapk cascade GO:0000165 107 0.070
appendage morphogenesis GO:0035107 397 0.069
appendage development GO:0048736 401 0.069
nucleosome assembly GO:0006334 35 0.066
neurological system process GO:0050877 358 0.065
wing disc morphogenesis GO:0007472 344 0.065
multi organism behavior GO:0051705 175 0.063
positive regulation of nitrogen compound metabolic process GO:0051173 354 0.062
nuclear division GO:0000280 332 0.062
negative regulation of macromolecule biosynthetic process GO:0010558 270 0.062
post embryonic appendage morphogenesis GO:0035120 385 0.059
negative regulation of nucleobase containing compound metabolic process GO:0045934 261 0.059
asymmetric stem cell division GO:0098722 49 0.057
steroid catabolic process GO:0006706 1 0.056
imaginal disc derived appendage development GO:0048737 399 0.055
establishment or maintenance of cell polarity GO:0007163 167 0.055
negative regulation of gene expression epigenetic GO:0045814 77 0.054
dna packaging GO:0006323 91 0.054
gene silencing GO:0016458 138 0.053
negative regulation of rna biosynthetic process GO:1902679 240 0.053
inter male aggressive behavior GO:0002121 60 0.053
negative regulation of biosynthetic process GO:0009890 277 0.052
positive regulation of signal transduction GO:0009967 223 0.050
small molecule metabolic process GO:0044281 305 0.049
negative regulation of nitrogen compound metabolic process GO:0051172 265 0.048
protein modification process GO:0036211 438 0.047
macromolecular complex assembly GO:0065003 256 0.047
stem cell proliferation GO:0072089 88 0.046
single organism behavior GO:0044708 391 0.046
single organism biosynthetic process GO:0044711 206 0.045
homeostatic process GO:0042592 199 0.044
regulation of gene expression epigenetic GO:0040029 128 0.044
adult behavior GO:0030534 137 0.044
organophosphate metabolic process GO:0019637 195 0.044
chromosome segregation GO:0007059 157 0.043
organic hydroxy compound metabolic process GO:1901615 83 0.043
negative regulation of phosphorus metabolic process GO:0010563 45 0.042
intracellular signal transduction GO:0035556 300 0.042
gliogenesis GO:0042063 80 0.041
negative regulation of cellular biosynthetic process GO:0031327 277 0.041
response to nutrient levels GO:0031667 114 0.040
negative regulation of rna metabolic process GO:0051253 251 0.040
cell division GO:0051301 248 0.040
eye development GO:0001654 323 0.040
mitotic nuclear division GO:0007067 213 0.040
death GO:0016265 284 0.038
imaginal disc derived wing morphogenesis GO:0007476 337 0.038
negative regulation of cell communication GO:0010648 223 0.037
regulation of phosphorus metabolic process GO:0051174 210 0.037
lipid metabolic process GO:0006629 121 0.037
regulation of cellular protein metabolic process GO:0032268 243 0.036
compound eye photoreceptor cell differentiation GO:0001751 140 0.035
eye morphogenesis GO:0048592 260 0.034
polyol biosynthetic process GO:0046173 3 0.034
ras protein signal transduction GO:0007265 88 0.034
regulation of tube architecture open tracheal system GO:0035152 68 0.034
positive regulation of nucleic acid templated transcription GO:1903508 266 0.033
anatomical structure homeostasis GO:0060249 97 0.033
positive regulation of developmental process GO:0051094 143 0.033
cellular catabolic process GO:0044248 372 0.033
regulation of growth GO:0040008 233 0.032
single organism catabolic process GO:0044712 228 0.031
tissue morphogenesis GO:0048729 297 0.031
response to organophosphorus GO:0046683 2 0.031
negative regulation of signal transduction GO:0009968 206 0.031
eye photoreceptor cell differentiation GO:0001754 145 0.030
signal transduction by phosphorylation GO:0023014 107 0.030
protein complex biogenesis GO:0070271 201 0.030
cellular amine metabolic process GO:0044106 12 0.029
response to ethanol GO:0045471 59 0.029
compound eye morphogenesis GO:0001745 249 0.029
compound eye development GO:0048749 307 0.029
negative regulation of response to stimulus GO:0048585 258 0.029
epithelial cell development GO:0002064 274 0.028
organonitrogen compound metabolic process GO:1901564 318 0.028
regulation of cellular amino acid metabolic process GO:0006521 0 0.028
programmed cell death GO:0012501 257 0.027
chromatin organization GO:0006325 207 0.027
stress activated mapk cascade GO:0051403 52 0.027
reciprocal meiotic recombination GO:0007131 19 0.027
sensory organ morphogenesis GO:0090596 260 0.027
asymmetric neuroblast division GO:0055059 33 0.027
meiotic cell cycle process GO:1903046 132 0.027
neuronal stem cell division GO:0036445 35 0.027
amine metabolic process GO:0009308 12 0.027
cellular macromolecular complex assembly GO:0034622 153 0.027
regulation of catabolic process GO:0009894 170 0.027
protein dna complex subunit organization GO:0071824 86 0.027
regulation of protein metabolic process GO:0051246 256 0.026
fat soluble vitamin metabolic process GO:0006775 1 0.026
morphogenesis of an epithelium GO:0002009 276 0.026
response to organic substance GO:0010033 284 0.026
aggressive behavior GO:0002118 63 0.026
xenobiotic catabolic process GO:0042178 1 0.026
positive regulation of cell communication GO:0010647 250 0.026
negative regulation of cellular macromolecule biosynthetic process GO:2000113 267 0.026
cell proliferation GO:0008283 299 0.026
neuroblast proliferation GO:0007405 74 0.025
open tracheal system development GO:0007424 204 0.025
protein complex assembly GO:0006461 200 0.025
phosphorylation GO:0016310 294 0.025
negative regulation of signaling GO:0023057 219 0.025
small gtpase mediated signal transduction GO:0007264 88 0.025
dendrite morphogenesis GO:0048813 199 0.024
regulation of gene silencing GO:0060968 63 0.024
sister chromatid segregation GO:0000819 92 0.024
photoreceptor cell differentiation GO:0046530 170 0.024
transcription from rna polymerase ii promoter GO:0006366 368 0.024
meiotic cell cycle GO:0051321 171 0.023
negative regulation of phosphate metabolic process GO:0045936 45 0.023
positive regulation of cellular amino acid metabolic process GO:0045764 0 0.023
regulation of cellular ketone metabolic process GO:0010565 3 0.023
regulation of anatomical structure size GO:0090066 163 0.023
negative regulation of cell cycle process GO:0010948 109 0.023
developmental growth GO:0048589 280 0.022
germarium derived egg chamber formation GO:0007293 101 0.022
non sensory hair organization GO:0035316 47 0.022
carboxylic acid metabolic process GO:0019752 92 0.022
positive regulation of phosphorus metabolic process GO:0010562 139 0.022
cellular ketone metabolic process GO:0042180 24 0.022
respiratory system development GO:0060541 213 0.022
response to alcohol GO:0097305 95 0.022
regulation of cellular catabolic process GO:0031329 157 0.021
organic cyclic compound catabolic process GO:1901361 168 0.021
axon development GO:0061564 297 0.021
organic substance catabolic process GO:1901575 308 0.021
response to oxygen containing compound GO:1901700 200 0.021
body morphogenesis GO:0010171 2 0.021
mating behavior GO:0007617 106 0.021
ribose phosphate metabolic process GO:0019693 145 0.020
regulation of response to stress GO:0080134 200 0.020
salivary gland development GO:0007431 162 0.020
regionalization GO:0003002 416 0.020
eye photoreceptor cell development GO:0042462 81 0.020
growth GO:0040007 359 0.020
mitotic sister chromatid segregation GO:0000070 87 0.020
embryo development ending in birth or egg hatching GO:0009792 152 0.019
cognition GO:0050890 141 0.019
retina development in camera type eye GO:0060041 4 0.019
biological adhesion GO:0022610 138 0.019
locomotory behavior GO:0007626 176 0.019
positive regulation of biosynthetic process GO:0009891 316 0.019
regulation of cellular amine metabolic process GO:0033238 3 0.019
neuroblast division GO:0055057 35 0.019
phagocytosis GO:0006909 215 0.019
regulation of mapk cascade GO:0043408 92 0.019
chromatin silencing GO:0006342 76 0.019
photoreceptor cell development GO:0042461 96 0.019
purine nucleoside metabolic process GO:0042278 127 0.019
behavioral response to ethanol GO:0048149 49 0.019
positive regulation of phosphate metabolic process GO:0045937 139 0.019
stem cell division GO:0017145 69 0.019
erk1 and erk2 cascade GO:0070371 39 0.019
heterochromatin organization GO:0070828 25 0.019
regulation of transport GO:0051049 181 0.018
cellular protein modification process GO:0006464 438 0.018
regulation of protein modification process GO:0031399 112 0.018
regulation of epithelial cell differentiation GO:0030856 4 0.018
proteolysis involved in cellular protein catabolic process GO:0051603 83 0.018
modification dependent macromolecule catabolic process GO:0043632 79 0.018
exocrine system development GO:0035272 162 0.018
protein modification by small protein conjugation GO:0032446 79 0.018
response to extracellular stimulus GO:0009991 116 0.018
apoptotic process GO:0006915 159 0.018
regulation of organelle organization GO:0033043 196 0.018
catabolic process GO:0009056 409 0.017
organic acid metabolic process GO:0006082 103 0.017
protein dna complex assembly GO:0065004 63 0.017
regulation of localization GO:0032879 275 0.017
organic hydroxy compound biosynthetic process GO:1901617 21 0.017
mitotic cell cycle checkpoint GO:0007093 88 0.017
positive regulation of cellular biosynthetic process GO:0031328 316 0.017
tube development GO:0035295 244 0.017
positive regulation of response to stimulus GO:0048584 323 0.016
somatic stem cell division GO:0048103 37 0.016
regulation of molecular function GO:0065009 217 0.016
g2 dna damage checkpoint GO:0031572 69 0.016
meiotic nuclear division GO:0007126 151 0.016
cellular protein catabolic process GO:0044257 83 0.016
macromolecule catabolic process GO:0009057 161 0.016
positive regulation of macromolecule metabolic process GO:0010604 405 0.016
cell adhesion GO:0007155 136 0.016
notch signaling pathway GO:0007219 120 0.016
regulation of chromosome organization GO:0033044 64 0.016
regulation of notch signaling pathway GO:0008593 100 0.016
endocytosis GO:0006897 310 0.016
response to abiotic stimulus GO:0009628 341 0.016
taxis GO:0042330 304 0.016
skin development GO:0043588 65 0.016
synaptic transmission GO:0007268 288 0.016
positive regulation of cellular catabolic process GO:0031331 95 0.015
multicellular organismal aging GO:0010259 140 0.015
neural precursor cell proliferation GO:0061351 75 0.015
positive regulation of gene expression GO:0010628 290 0.015
positive regulation of rna metabolic process GO:0051254 271 0.015
dna conformation change GO:0071103 105 0.015
organic substance transport GO:0071702 257 0.015
regulation of intracellular signal transduction GO:1902531 236 0.015
columnar cuboidal epithelial cell development GO:0002066 249 0.015
axon guidance GO:0007411 233 0.015
vesicle mediated transport GO:0016192 381 0.015
protein transport GO:0015031 155 0.015
actin filament bundle assembly GO:0051017 26 0.015
nucleosome organization GO:0034728 59 0.015
enzyme linked receptor protein signaling pathway GO:0007167 179 0.015
jnk cascade GO:0007254 50 0.015
reproductive system development GO:0061458 74 0.015
response to light stimulus GO:0009416 124 0.015
organophosphate biosynthetic process GO:0090407 46 0.015
positive regulation of rna biosynthetic process GO:1902680 266 0.015
regulation of anatomical structure morphogenesis GO:0022603 242 0.015
actin cytoskeleton organization GO:0030036 206 0.015
regulation of erk1 and erk2 cascade GO:0070372 39 0.014
glial cell migration GO:0008347 31 0.014
cellular protein localization GO:0034613 160 0.014
nucleoside catabolic process GO:0009164 112 0.014
protein maturation GO:0051604 71 0.014
hormone catabolic process GO:0042447 3 0.014
transmembrane receptor protein tyrosine kinase signaling pathway GO:0007169 116 0.014
cellular nitrogen compound catabolic process GO:0044270 165 0.014
positive regulation of signaling GO:0023056 243 0.014
protein k48 linked ubiquitination GO:0070936 3 0.014
regulation of vesicle mediated transport GO:0060627 59 0.014
regulation of small gtpase mediated signal transduction GO:0051056 93 0.014
positive regulation of nucleobase containing compound metabolic process GO:0045935 332 0.014
telencephalon development GO:0021537 2 0.014
regulation of cell cycle phase transition GO:1901987 130 0.014
r7 cell differentiation GO:0045466 43 0.014
regulation of cellular response to stress GO:0080135 89 0.014
cell death GO:0008219 279 0.014
response to other organism GO:0051707 293 0.014
organonitrogen compound catabolic process GO:1901565 128 0.014
negative regulation of cellular protein metabolic process GO:0032269 85 0.014
establishment of protein localization GO:0045184 163 0.014
positive regulation of cellular amine metabolic process GO:0033240 0 0.014
response to mercury ion GO:0046689 3 0.014
negative regulation of developmental process GO:0051093 201 0.014
cell aging GO:0007569 2 0.014
chemotaxis GO:0006935 249 0.014
regulation of proteasomal protein catabolic process GO:0061136 39 0.014
central nervous system development GO:0007417 201 0.013
oxoacid metabolic process GO:0043436 103 0.013
chromosome separation GO:0051304 42 0.013
positive regulation of catabolic process GO:0009896 105 0.013
connective tissue development GO:0061448 3 0.013
actin filament bundle organization GO:0061572 28 0.013
actin filament based process GO:0030029 220 0.013
purine ribonucleotide metabolic process GO:0009150 145 0.013
response to biotic stimulus GO:0009607 294 0.013
insecticide catabolic process GO:0046701 1 0.013
stress activated protein kinase signaling cascade GO:0031098 55 0.013
response to starvation GO:0042594 97 0.013
purine nucleoside triphosphate metabolic process GO:0009144 119 0.013
forebrain development GO:0030900 2 0.013
positive regulation of mapk cascade GO:0043410 63 0.013
immune system process GO:0002376 347 0.013
anterior posterior pattern specification GO:0009952 136 0.013
reproductive behavior GO:0019098 122 0.013
neuron recognition GO:0008038 101 0.013
negative regulation of multicellular organismal process GO:0051241 142 0.013
autophagy GO:0006914 108 0.013
camera type eye development GO:0043010 4 0.013
cellular response to chemical stimulus GO:0070887 199 0.012
regulation of programmed cell death GO:0043067 152 0.012
developmental maturation GO:0021700 172 0.012
gland morphogenesis GO:0022612 145 0.012
cellular macromolecule catabolic process GO:0044265 136 0.012
regulation of cellular protein catabolic process GO:1903362 44 0.012
positive regulation of macromolecule biosynthetic process GO:0010557 283 0.012
regulation of chromosome segregation GO:0051983 32 0.012
epithelial tube morphogenesis GO:0060562 88 0.012
negative regulation of nervous system development GO:0051961 92 0.012
spindle organization GO:0007051 253 0.012
purine nucleotide metabolic process GO:0006163 146 0.012
regulation of stress activated mapk cascade GO:0032872 41 0.012
oocyte differentiation GO:0009994 145 0.012
hair cell differentiation GO:0035315 47 0.012
positive regulation of cell development GO:0010720 61 0.012
salivary gland morphogenesis GO:0007435 145 0.012
purine nucleotide catabolic process GO:0006195 109 0.012
epithelial cell differentiation GO:0030855 322 0.012
lauric acid metabolic process GO:0048252 1 0.012
ameboidal type cell migration GO:0001667 151 0.012
positive regulation of cell motility GO:2000147 3 0.012
embryonic morphogenesis GO:0048598 206 0.012
proteolysis GO:0006508 192 0.012
positive regulation of cell migration GO:0030335 2 0.012
protein modification by small protein conjugation or removal GO:0070647 106 0.012
protein catabolic process GO:0030163 101 0.012
regulation of mitosis GO:0007088 56 0.012
dephosphorylation GO:0016311 51 0.011
reciprocal dna recombination GO:0035825 19 0.011
cell motility GO:0048870 251 0.011
positive regulation of phosphorylation GO:0042327 87 0.011
cell maturation GO:0048469 144 0.011
learning or memory GO:0007611 141 0.011
heterocycle catabolic process GO:0046700 166 0.011
hindgut development GO:0061525 58 0.011
adult locomotory behavior GO:0008344 76 0.011
mating GO:0007618 120 0.011
mitotic g2 dna damage checkpoint GO:0007095 69 0.011
regulation of catalytic activity GO:0050790 185 0.011
positive regulation of organelle organization GO:0010638 65 0.011
mitotic dna integrity checkpoint GO:0044774 75 0.011
regulation of sister chromatid segregation GO:0033045 28 0.011
sulfur compound metabolic process GO:0006790 59 0.011
modification dependent protein catabolic process GO:0019941 78 0.011
negative regulation of cell death GO:0060548 81 0.011
memory GO:0007613 94 0.011
golgi organization GO:0007030 66 0.011
cell growth GO:0016049 108 0.011
embryonic development via the syncytial blastoderm GO:0001700 148 0.011
regulation of ras protein signal transduction GO:0046578 93 0.011
axis specification GO:0009798 167 0.011
response to hexose GO:0009746 3 0.011
epidermis development GO:0008544 65 0.011
regulation of multicellular organismal development GO:2000026 414 0.011
regulation of chromatin silencing GO:0031935 36 0.011
regulation of protein catabolic process GO:0042176 55 0.011
peptidyl threonine modification GO:0018210 3 0.011
positive regulation of transcription dna templated GO:0045893 266 0.011
negative regulation of mitotic cell cycle phase transition GO:1901991 103 0.011
photoreceptor cell fate commitment GO:0046552 41 0.011
nucleobase containing small molecule metabolic process GO:0055086 174 0.010
regulation of cellular component biogenesis GO:0044087 201 0.010
hindbrain development GO:0030902 2 0.010
leg disc morphogenesis GO:0007478 80 0.010
regulation of developmental growth GO:0048638 174 0.010
defense response to other organism GO:0098542 225 0.010
response to radiation GO:0009314 155 0.010
maintenance of location GO:0051235 73 0.010
nucleoside phosphate catabolic process GO:1901292 110 0.010
lateral inhibition GO:0046331 206 0.010
purine containing compound metabolic process GO:0072521 155 0.010
regulation of epidermal growth factor receptor signaling pathway GO:0042058 42 0.010
ribonucleotide metabolic process GO:0009259 145 0.010
cellular response to oxygen containing compound GO:1901701 79 0.010
neuron projection guidance GO:0097485 241 0.010
regulation of transcription from rna polymerase ii promoter GO:0006357 378 0.010
response to temperature stimulus GO:0009266 106 0.010
regulation of tube size GO:0035150 46 0.010
regulation of tube size open tracheal system GO:0035151 43 0.010
single organism cell adhesion GO:0098602 47 0.010
telomere organization GO:0032200 21 0.010
associative learning GO:0008306 65 0.010
intracellular protein transport GO:0006886 104 0.010
gland development GO:0048732 191 0.010
sex differentiation GO:0007548 81 0.010

HP5 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in fly and predicted with the fly functional network.

Disease DO term ID Size Probability Func Analog Org
disease of anatomical entity DOID:7 0 0.021
cardiovascular system disease DOID:1287 0 0.011
vascular disease DOID:178 0 0.011
artery disease DOID:0050828 0 0.011