Drosophila melanogaster

249 known processes

Moe (Dmel_CG10701)

Moesin

(Aliases: l(1)G0415,D17,anon-WO03040301.157,Dmoe,anon-WO03040301.155,l(1)G0323,EMR1,anon-WO03040301.159,anon-WO03040301.161,l(1)G0067,Dmel\CG10701,CG10701,Emr1,ERM,moesin/ezrin/radixin homolog mRNA,l(1)G0404,moe,dMoe)

Moe biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
respiratory system development GO:0060541 213 1.000
open tracheal system development GO:0007424 204 0.999
photoreceptor cell differentiation GO:0046530 170 0.997
macromolecular complex assembly GO:0065003 256 0.991
Worm
actin filament based process GO:0030029 220 0.990
appendage morphogenesis GO:0035107 397 0.987
Fly
tissue morphogenesis GO:0048729 297 0.986
eye morphogenesis GO:0048592 260 0.979
positive regulation of gene expression GO:0010628 290 0.977
Human
larval development GO:0002164 104 0.976
regulation of cell proliferation GO:0042127 163 0.972
actomyosin structure organization GO:0031032 56 0.972
Worm
determination of adult lifespan GO:0008340 137 0.970
Worm
programmed cell death GO:0012501 257 0.967
Worm Fly
establishment of localization in cell GO:0051649 402 0.963
muscle structure development GO:0061061 224 0.960
Worm
establishment or maintenance of cell polarity GO:0007163 167 0.952
sensory organ morphogenesis GO:0090596 260 0.948
appendage development GO:0048736 401 0.939
Fly
actin cytoskeleton organization GO:0030036 206 0.938
establishment or maintenance of apical basal cell polarity GO:0035088 34 0.937
compound eye development GO:0048749 307 0.936
regulation of tube architecture open tracheal system GO:0035152 68 0.934
protein complex assembly GO:0006461 200 0.931
Worm
post embryonic appendage morphogenesis GO:0035120 385 0.924
Fly
dorsal closure GO:0007391 79 0.924
protein localization GO:0008104 284 0.923
Mouse Worm Fly
sex differentiation GO:0007548 81 0.923
female germ line cyst formation GO:0048135 42 0.923
negative regulation of response to stimulus GO:0048585 258 0.921
morphogenesis of an epithelium GO:0002009 276 0.921
branching involved in open tracheal system development GO:0060446 45 0.917
negative regulation of cellular macromolecule biosynthetic process GO:2000113 267 0.902
protein complex biogenesis GO:0070271 201 0.898
Worm
single organism cellular localization GO:1902580 180 0.886
imaginal disc derived appendage morphogenesis GO:0035114 395 0.881
Fly
male gamete generation GO:0048232 201 0.878
Fly
negative regulation of signaling GO:0023057 219 0.873
positive regulation of macromolecule biosynthetic process GO:0010557 283 0.873
striated muscle cell development GO:0055002 50 0.858
Worm
muscle organ development GO:0007517 127 0.853
regulation of protein metabolic process GO:0051246 256 0.848
Fly
cellular macromolecule localization GO:0070727 220 0.842
Worm Fly
cellular protein localization GO:0034613 160 0.838
Worm Fly
nuclear division GO:0000280 332 0.837
imaginal disc derived appendage development GO:0048737 399 0.834
Fly
negative regulation of cell communication GO:0010648 223 0.827
regulation of tube size GO:0035150 46 0.824
purine ribonucleoside catabolic process GO:0046130 112 0.820
purine nucleoside triphosphate metabolic process GO:0009144 119 0.811
glycosyl compound catabolic process GO:1901658 112 0.809
aging GO:0007568 143 0.804
Worm
multicellular organismal aging GO:0010259 140 0.800
Worm
regulation of programmed cell death GO:0043067 152 0.796
Fly
cellular component assembly involved in morphogenesis GO:0010927 151 0.796
Worm
regulation of anatomical structure morphogenesis GO:0022603 242 0.792
Fly
synaptic growth at neuromuscular junction GO:0051124 119 0.789
nucleotide catabolic process GO:0009166 109 0.786
carbohydrate derivative catabolic process GO:1901136 118 0.784
nucleoside triphosphate catabolic process GO:0009143 108 0.783
positive regulation of cellular biosynthetic process GO:0031328 316 0.782
positive regulation of macromolecule metabolic process GO:0010604 405 0.764
Human Fly
cytoskeleton dependent intracellular transport GO:0030705 44 0.760
negative regulation of nervous system development GO:0051961 92 0.757
Fly
nucleotide metabolic process GO:0009117 161 0.751
eye photoreceptor cell differentiation GO:0001754 145 0.750
purine containing compound catabolic process GO:0072523 112 0.742
axonogenesis GO:0007409 290 0.737
purine ribonucleoside triphosphate catabolic process GO:0009207 108 0.735
regulation of cell development GO:0060284 215 0.730
Fly
ovarian follicle cell development GO:0030707 248 0.720
microtubule based movement GO:0007018 51 0.719
germarium derived female germ line cyst formation GO:0030727 42 0.710
negative regulation of signal transduction GO:0009968 206 0.702
tube development GO:0035295 244 0.690
Zebrafish Worm
spermatid development GO:0007286 98 0.687
Fly
nucleoside catabolic process GO:0009164 112 0.687
purine ribonucleotide catabolic process GO:0009154 109 0.686
single organism behavior GO:0044708 391 0.684
negative regulation of cellular metabolic process GO:0031324 382 0.681
regulation of tube size open tracheal system GO:0035151 43 0.679
compound eye morphogenesis GO:0001745 249 0.675
positive regulation of biosynthetic process GO:0009891 316 0.670
nucleoside triphosphate metabolic process GO:0009141 120 0.655
regulation of notch signaling pathway GO:0008593 100 0.650
apoptotic process GO:0006915 159 0.635
Worm Fly
ribose phosphate metabolic process GO:0019693 145 0.633
oocyte axis specification GO:0007309 108 0.628
cell motility GO:0048870 251 0.625
Human Zebrafish Worm
striated muscle myosin thick filament assembly GO:0071688 3 0.615
Worm
negative regulation of cell differentiation GO:0045596 143 0.600
Fly
negative regulation of nucleic acid templated transcription GO:1903507 240 0.594
intracellular transport GO:0046907 228 0.589
Fly
negative regulation of gene expression GO:0010629 387 0.587
reproductive structure development GO:0048608 74 0.583
ribonucleoside metabolic process GO:0009119 127 0.581
cell projection assembly GO:0030031 94 0.579
Mouse Rat
protein transport GO:0015031 155 0.574
ribonucleoside triphosphate metabolic process GO:0009199 119 0.574
positive regulation of nitrogen compound metabolic process GO:0051173 354 0.572
catabolic process GO:0009056 409 0.565
phosphorylation GO:0016310 294 0.557
Fly
regulation of synaptic growth at neuromuscular junction GO:0008582 89 0.552
vesicle mediated transport GO:0016192 381 0.547
basement membrane organization GO:0071711 10 0.541
positive regulation of programmed cell death GO:0043068 62 0.539
chorion containing eggshell formation GO:0007304 105 0.535
epithelial cell differentiation GO:0030855 322 0.535
Human Rat
death GO:0016265 284 0.529
Worm Fly
multicellular organismal homeostasis GO:0048871 41 0.526
posttranscriptional regulation of gene expression GO:0010608 145 0.522
negative regulation of transcription dna templated GO:0045892 237 0.520
nucleobase containing compound catabolic process GO:0034655 165 0.520
neuron projection guidance GO:0097485 241 0.519
organelle fission GO:0048285 340 0.517
gene silencing GO:0016458 138 0.508
cellular response to chemical stimulus GO:0070887 199 0.504
purine nucleoside triphosphate catabolic process GO:0009146 108 0.502
gonad development GO:0008406 50 0.501
regulation of intracellular signal transduction GO:1902531 236 0.498
Fly
neurological system process GO:0050877 358 0.496
cellular nitrogen compound catabolic process GO:0044270 165 0.486
circulatory system development GO:0072359 82 0.482
Zebrafish
cell death GO:0008219 279 0.478
Worm Fly
cellular response to organic substance GO:0071310 132 0.478
imaginal disc derived wing morphogenesis GO:0007476 337 0.476
Fly
germ line cyst formation GO:0048134 44 0.471
purine ribonucleoside triphosphate metabolic process GO:0009205 119 0.471
localization of cell GO:0051674 257 0.470
Human Zebrafish Worm
ameboidal type cell migration GO:0001667 151 0.469
Zebrafish
meiotic cell cycle GO:0051321 171 0.468
Fly
response to abiotic stimulus GO:0009628 341 0.468
ribonucleotide metabolic process GO:0009259 145 0.467
establishment of protein localization GO:0045184 163 0.465
positive regulation of nucleobase containing compound metabolic process GO:0045935 332 0.461
organophosphate catabolic process GO:0046434 112 0.460
border follicle cell migration GO:0007298 113 0.457
post golgi vesicle mediated transport GO:0006892 11 0.457
tube morphogenesis GO:0035239 191 0.455
Zebrafish Worm
epidermal cell differentiation GO:0009913 51 0.455
branching morphogenesis of an epithelial tube GO:0048754 45 0.453
intracellular signal transduction GO:0035556 300 0.448
Fly
cell migration GO:0016477 238 0.443
Human Zebrafish Worm
cellular catabolic process GO:0044248 372 0.443
aromatic compound catabolic process GO:0019439 166 0.437
wing disc morphogenesis GO:0007472 344 0.435
Fly
heart development GO:0007507 82 0.432
heterocycle catabolic process GO:0046700 166 0.428
purine nucleoside catabolic process GO:0006152 112 0.425
organophosphate metabolic process GO:0019637 195 0.416
negative regulation of developmental process GO:0051093 201 0.412
Fly
immune system process GO:0002376 347 0.412
Human
positive regulation of rna metabolic process GO:0051254 271 0.412
embryonic development via the syncytial blastoderm GO:0001700 148 0.406
purine nucleotide catabolic process GO:0006195 109 0.404
nucleoside phosphate catabolic process GO:1901292 110 0.403
nucleoside metabolic process GO:0009116 127 0.400
organic cyclic compound catabolic process GO:1901361 168 0.399
cortical actin cytoskeleton organization GO:0030866 24 0.396
ribonucleoside catabolic process GO:0042454 112 0.395
multicellular organismal reproductive behavior GO:0033057 110 0.393
immune response GO:0006955 246 0.392
cell junction assembly GO:0034329 42 0.385
response to external biotic stimulus GO:0043207 293 0.383
positive regulation of nucleic acid templated transcription GO:1903508 266 0.383
negative regulation of rna biosynthetic process GO:1902679 240 0.375
carbohydrate derivative metabolic process GO:1901135 217 0.371
secretion by cell GO:0032940 101 0.369
defense response to other organism GO:0098542 225 0.369
purine nucleoside metabolic process GO:0042278 127 0.366
secretion GO:0046903 109 0.366
nucleoside phosphate metabolic process GO:0006753 162 0.364
eye development GO:0001654 323 0.361
ribonucleotide catabolic process GO:0009261 109 0.360
establishment of protein localization to membrane GO:0090150 11 0.360
guanosine containing compound metabolic process GO:1901068 74 0.357
reproductive system development GO:0061458 74 0.353
biological adhesion GO:0022610 138 0.350
Human
response to bacterium GO:0009617 198 0.349
purine nucleotide metabolic process GO:0006163 146 0.349
endocytosis GO:0006897 310 0.344
regulation of cell shape GO:0008360 113 0.342
formation of anatomical boundary GO:0048859 37 0.335
ribonucleoside triphosphate catabolic process GO:0009203 108 0.334
nucleobase containing small molecule metabolic process GO:0055086 174 0.331
skin development GO:0043588 65 0.329
molting cycle GO:0042303 56 0.329
defense response GO:0006952 300 0.329
regulation of embryonic development GO:0045995 68 0.323
regulation of multicellular organismal development GO:2000026 414 0.322
Fly
muscle cell development GO:0055001 50 0.319
Worm
muscle fiber development GO:0048747 12 0.318
regulation of cellular protein metabolic process GO:0032268 243 0.315
Fly
immune system development GO:0002520 57 0.314
neuromuscular junction development GO:0007528 149 0.314
purine ribonucleotide metabolic process GO:0009150 145 0.314
regulation of neurogenesis GO:0050767 158 0.311
Fly
regulation of heart morphogenesis GO:2000826 3 0.303
notch signaling pathway GO:0007219 120 0.303
ovarian follicle cell migration GO:0007297 121 0.301
regulation of molecular function GO:0065009 217 0.299
negative regulation of glial cell proliferation GO:0060253 6 0.298
Fly
axon guidance GO:0007411 233 0.298
compound eye photoreceptor cell differentiation GO:0001751 140 0.296
dorsal closure amnioserosa morphology change GO:0046664 7 0.295
regulation of transcription from rna polymerase ii promoter GO:0006357 378 0.287
cardiac muscle tissue development GO:0048738 9 0.282
microtubule based transport GO:0010970 42 0.281
mitotic nuclear division GO:0007067 213 0.280
developmental growth GO:0048589 280 0.278
Fly
regulation of nervous system development GO:0051960 248 0.275
Fly
chromatin silencing GO:0006342 76 0.274
receptor mediated endocytosis GO:0006898 21 0.271
Mouse Worm
response to biotic stimulus GO:0009607 294 0.264
morphogenesis of embryonic epithelium GO:0016331 94 0.263
morphogenesis of a branching epithelium GO:0061138 45 0.263
regulation of immune system process GO:0002682 176 0.263
Human
meiotic nuclear division GO:0007126 151 0.259
Fly
taxis GO:0042330 304 0.252
establishment of tissue polarity GO:0007164 87 0.248
negative regulation of biosynthetic process GO:0009890 277 0.248
gland development GO:0048732 191 0.247
morphogenesis of larval imaginal disc epithelium GO:0016335 5 0.243
myofibril assembly GO:0030239 36 0.241
Worm
brain development GO:0007420 120 0.237
positive regulation of rna biosynthetic process GO:1902680 266 0.235
guanosine containing compound catabolic process GO:1901069 74 0.234
positive regulation of transcription dna templated GO:0045893 266 0.234
dna metabolic process GO:0006259 227 0.234
reproductive behavior GO:0019098 122 0.231
regulation of protein phosphorylation GO:0001932 64 0.230
Fly
regulation of membrane potential GO:0042391 35 0.228
negative regulation of macromolecule biosynthetic process GO:0010558 270 0.223
developmental maturation GO:0021700 172 0.218
organic substance catabolic process GO:1901575 308 0.218
cell aging GO:0007569 2 0.216
instar larval development GO:0002168 55 0.215
regulation of phosphorylation GO:0042325 147 0.213
Fly
establishment of protein localization to plasma membrane GO:0090002 9 0.213
regulation of transport GO:0051049 181 0.210
negative regulation of cell development GO:0010721 62 0.209
Fly
molting cycle chitin based cuticle GO:0007591 56 0.208
epidermis development GO:0008544 65 0.206
digestive system development GO:0055123 149 0.205
Zebrafish
extracellular structure organization GO:0043062 46 0.205
protein localization to nucleus GO:0034504 55 0.203
salivary gland development GO:0007431 162 0.203
positive regulation of cell proliferation GO:0008284 47 0.203
organic substance transport GO:0071702 257 0.197
cellular protein complex assembly GO:0043623 71 0.196
Worm
cellular ketone metabolic process GO:0042180 24 0.196
endomembrane system organization GO:0010256 119 0.194
Worm Fly
protein localization to organelle GO:0033365 82 0.194
cell junction organization GO:0034330 57 0.193
multi organism behavior GO:0051705 175 0.193
cognition GO:0050890 141 0.192
dendrite development GO:0016358 204 0.192
regulation of developmental growth GO:0048638 174 0.191
Fly
morphogenesis of a polarized epithelium GO:0001738 93 0.189
organonitrogen compound catabolic process GO:1901565 128 0.188
negative regulation of cell proliferation GO:0008285 69 0.188
Fly
cell proliferation GO:0008283 299 0.187
striated muscle cell differentiation GO:0051146 90 0.185
Worm
regulation of cell morphogenesis GO:0022604 163 0.181
membrane organization GO:0061024 112 0.180
Worm Fly
muscle cell differentiation GO:0042692 103 0.174
Worm
stem cell development GO:0048864 79 0.169
skeletal muscle fiber development GO:0048741 3 0.166
single organism intracellular transport GO:1902582 207 0.165
Fly
gtp metabolic process GO:0046039 72 0.163
mesoderm development GO:0007498 78 0.161
eggshell formation GO:0030703 105 0.161
apoptotic signaling pathway GO:0097190 27 0.161
purine ribonucleoside metabolic process GO:0046128 127 0.159
positive regulation of response to stimulus GO:0048584 323 0.159
gtp catabolic process GO:0006184 72 0.155
response to nutrient levels GO:0031667 114 0.154
positive regulation of signal transduction GO:0009967 223 0.153
epithelial structure maintenance GO:0010669 17 0.150
cell cell junction organization GO:0045216 55 0.145
epithelial cell development GO:0002064 274 0.145
Human
stem cell maintenance GO:0019827 67 0.144
genitalia development GO:0048806 26 0.144
organ growth GO:0035265 56 0.143
Fly
germarium derived egg chamber formation GO:0007293 101 0.139
genitalia morphogenesis GO:0035112 16 0.138
response to wounding GO:0009611 94 0.137
skeletal muscle tissue development GO:0007519 13 0.137
cellular macromolecular complex assembly GO:0034622 153 0.136
Worm
skeletal muscle organ development GO:0060538 48 0.136
muscle tissue development GO:0060537 30 0.135
transcription from rna polymerase ii promoter GO:0006366 368 0.135
maintenance of location in cell GO:0051651 28 0.134
epithelial tube morphogenesis GO:0060562 88 0.134
Zebrafish
regulation of anatomical structure size GO:0090066 163 0.133
positive regulation of cell death GO:0010942 69 0.131
glycosyl compound metabolic process GO:1901657 127 0.128
imaginal disc growth GO:0007446 37 0.127
response to hormone GO:0009725 45 0.126
regulation of phosphorus metabolic process GO:0051174 210 0.125
Fly
growth GO:0040007 359 0.125
Fly
regulation of imaginal disc derived wing size GO:0044719 20 0.125
cell substrate adhesion GO:0031589 10 0.124
developmental growth involved in morphogenesis GO:0060560 65 0.124
regulation of cytoskeleton organization GO:0051493 89 0.123
rhabdomere development GO:0042052 38 0.122
spermatogenesis GO:0007283 200 0.122
Fly
translation GO:0006412 69 0.119
positive regulation of secretion GO:0051047 22 0.118
epithelial cell migration GO:0010631 148 0.118
regulation of gene expression epigenetic GO:0040029 128 0.116
response to lipid GO:0033993 38 0.114
establishment of protein localization to organelle GO:0072594 62 0.113
stem cell differentiation GO:0048863 117 0.112
oocyte differentiation GO:0009994 145 0.109
positive regulation of establishment of protein localization to plasma membrane GO:0090004 3 0.106
negative regulation of organ growth GO:0046621 15 0.106
Fly
purine containing compound metabolic process GO:0072521 155 0.106
positive regulation of developmental process GO:0051094 143 0.105
positive regulation of molecular function GO:0044093 136 0.105
protein import into nucleus GO:0006606 51 0.099
negative regulation of nitrogen compound metabolic process GO:0051172 265 0.099
intracellular mrna localization involved in anterior posterior axis specification GO:0060811 53 0.099
Fly
single organism nuclear import GO:1902593 51 0.099
dorsal trunk growth open tracheal system GO:0035001 7 0.099
mushroom body development GO:0016319 70 0.097
defense response to bacterium GO:0042742 178 0.095
adherens junction organization GO:0034332 27 0.095
organelle assembly GO:0070925 198 0.094
Worm
positive regulation of cell communication GO:0010647 250 0.094
cell competition in a multicellular organism GO:0035212 10 0.093
synapse assembly GO:0007416 143 0.092
hair cell differentiation GO:0035315 47 0.092
negative regulation of neurogenesis GO:0050768 53 0.091
Fly
positive regulation of apoptotic process GO:0043065 47 0.091
establishment or maintenance of bipolar cell polarity GO:0061245 34 0.091
regulation of innate immune response GO:0045088 71 0.090
positive regulation of cell motility GO:2000147 3 0.089
positive regulation of cell migration GO:0030335 2 0.089
embryo development ending in birth or egg hatching GO:0009792 152 0.088
Worm
positive regulation of cell morphogenesis involved in differentiation GO:0010770 12 0.087
regulation of purine nucleotide metabolic process GO:1900542 62 0.087
regulation of epidermal cell differentiation GO:0045604 3 0.087
axis specification GO:0009798 167 0.083
single organism biosynthetic process GO:0044711 206 0.083
chemotaxis GO:0006935 249 0.083
response to organic substance GO:0010033 284 0.082
positive regulation of cellular component organization GO:0051130 156 0.081
protein localization to membrane GO:0072657 19 0.081
Worm Fly
regulation of secretion GO:0051046 44 0.081
positive regulation of catalytic activity GO:0043085 118 0.081
regionalization GO:0003002 416 0.080
tissue homeostasis GO:0001894 36 0.079
regulation of protein localization GO:0032880 76 0.079
negative regulation of intracellular signal transduction GO:1902532 57 0.079
regulation of dna binding GO:0051101 10 0.078
regulation of cellular component biogenesis GO:0044087 201 0.077
regulation of synapse assembly GO:0051963 94 0.077
response to light stimulus GO:0009416 124 0.077
cellular response to oxygen containing compound GO:1901701 79 0.076
regulation of localization GO:0032879 275 0.076
macromolecule catabolic process GO:0009057 161 0.075
response to organic cyclic compound GO:0014070 89 0.075
mating behavior GO:0007617 106 0.075
photoreceptor cell development GO:0042461 96 0.075
actin filament bundle assembly GO:0051017 26 0.074
Human
dna replication GO:0006260 48 0.074
apical junction assembly GO:0043297 32 0.074
anatomical structure homeostasis GO:0060249 97 0.073
chromosome organization GO:0051276 360 0.073
cell growth GO:0016049 108 0.073
Fly
dorsal closure elongation of leading edge cells GO:0007394 10 0.072
positive regulation of developmental growth GO:0048639 62 0.072
negative regulation of transcription from rna polymerase ii promoter GO:0000122 119 0.071
positive regulation of transcription from rna polymerase ii promoter GO:0045944 204 0.071
response to radiation GO:0009314 155 0.069
negative regulation of multicellular organismal process GO:0051241 142 0.069
Fly
negative regulation of phosphorus metabolic process GO:0010563 45 0.069
regulation of cell death GO:0010941 173 0.068
Fly
pseudocleavage involved in syncytial blastoderm formation GO:0030589 9 0.068
cell maturation GO:0048469 144 0.068
regulation of apoptotic process GO:0042981 130 0.068
Fly
positive regulation of protein localization to plasma membrane GO:1903078 3 0.068
centrosome organization GO:0051297 163 0.067
immune response regulating signaling pathway GO:0002764 2 0.066
detection of external stimulus GO:0009581 66 0.066
maintenance of protein location in cell GO:0032507 26 0.065
negative regulation of growth GO:0045926 84 0.065
Fly
regulation of protein stability GO:0031647 43 0.065
positive regulation of cellular protein metabolic process GO:0032270 118 0.064
Fly
response to lipopolysaccharide GO:0032496 4 0.064
regulation of muscle organ development GO:0048634 13 0.064
morphogenesis of a branching structure GO:0001763 45 0.064
homeostatic process GO:0042592 199 0.063
enzyme linked receptor protein signaling pathway GO:0007167 179 0.062
Fly
development of primary sexual characteristics GO:0045137 50 0.061
regulation of immune response GO:0050776 118 0.061
eye photoreceptor cell development GO:0042462 81 0.061
cell type specific apoptotic process GO:0097285 38 0.060
positive regulation of locomotion GO:0040017 8 0.060
actin filament organization GO:0007015 126 0.060
Human Worm
nephron epithelium development GO:0072009 3 0.059
digestive tract development GO:0048565 149 0.058
Zebrafish
positive regulation of cell adhesion GO:0045785 10 0.058
ras protein signal transduction GO:0007265 88 0.057
initiation of dorsal closure GO:0007392 12 0.057
apoptotic cell clearance GO:0043277 14 0.056
positive regulation of cellular component biogenesis GO:0044089 80 0.054
g protein coupled receptor signaling pathway GO:0007186 136 0.054
cell fate specification GO:0001708 71 0.054
gene silencing by rna GO:0031047 57 0.053
dorsal closure spreading of leading edge cells GO:0007395 4 0.053
positive regulation of synaptic growth at neuromuscular junction GO:0045887 26 0.053
spindle organization GO:0007051 253 0.053
establishment of planar polarity GO:0001736 87 0.052
head development GO:0060322 135 0.051
jak stat cascade GO:0007259 49 0.051
extracellular matrix organization GO:0030198 32 0.051
maintenance of location GO:0051235 73 0.050
eye photoreceptor cell fate commitment GO:0042706 37 0.049
positive regulation of multicellular organismal process GO:0051240 143 0.049
regulation of translation GO:0006417 56 0.049
embryonic axis specification GO:0000578 107 0.049
r7 cell differentiation GO:0045466 43 0.049
dendrite morphogenesis GO:0048813 199 0.049
protein phosphorylation GO:0006468 169 0.048
Fly
regulation of organ morphogenesis GO:2000027 78 0.048
Fly
regulation of protein modification process GO:0031399 112 0.048
Fly
plasma membrane organization GO:0007009 26 0.048
Worm Fly
regulation of epithelial cell proliferation GO:0050678 4 0.047
embryonic digestive tract morphogenesis GO:0048557 4 0.047
epithelial cell proliferation GO:0050673 15 0.046
tripartite regional subdivision GO:0007351 103 0.046
negative regulation of phosphate metabolic process GO:0045936 45 0.046
single organism membrane organization GO:0044802 93 0.045
Worm Fly
response to ketone GO:1901654 34 0.044
regulation of epithelial cell differentiation GO:0030856 4 0.044
imaginal disc derived wing vein morphogenesis GO:0008586 44 0.044
mitotic spindle organization GO:0007052 220 0.044
golgi organization GO:0007030 66 0.044
male sex differentiation GO:0046661 25 0.044
exocrine system development GO:0035272 162 0.043
negative regulation of programmed cell death GO:0043069 72 0.043
nerve development GO:0021675 6 0.043
negative regulation of phosphorylation GO:0042326 35 0.042
striated muscle tissue development GO:0014706 27 0.042
regulation of tube diameter open tracheal system GO:0035158 11 0.042
negative regulation of apoptotic process GO:0043066 63 0.042
defense response to gram negative bacterium GO:0050829 94 0.041
olfactory behavior GO:0042048 97 0.041
positive regulation of nervous system development GO:0051962 69 0.041
glial cell differentiation GO:0010001 35 0.041
photoreceptor cell fate commitment GO:0046552 41 0.040
embryonic morphogenesis GO:0048598 206 0.040
Zebrafish
cell recognition GO:0008037 102 0.040
negative regulation of cellular biosynthetic process GO:0031327 277 0.040
cellular macromolecule catabolic process GO:0044265 136 0.040
protein localization to plasma membrane GO:0072659 13 0.039
Worm Fly
germ line stem cell maintenance GO:0030718 50 0.039
cellular response to organonitrogen compound GO:0071417 36 0.039
regulation of phosphate metabolic process GO:0019220 210 0.039
Fly
regulation of apoptotic signaling pathway GO:2001233 10 0.039
response to other organism GO:0051707 293 0.039
single organism catabolic process GO:0044712 228 0.039
substrate adhesion dependent cell spreading GO:0034446 2 0.038
cellular protein catabolic process GO:0044257 83 0.038
hindgut morphogenesis GO:0007442 58 0.037
myotube cell development GO:0014904 3 0.037
positive regulation of cell development GO:0010720 61 0.036
positive regulation of cell growth GO:0030307 19 0.036
immune response activating signal transduction GO:0002757 2 0.036
cellular response to endogenous stimulus GO:0071495 80 0.036
positive regulation of signaling GO:0023056 243 0.036
myosin filament organization GO:0031033 5 0.035
Worm
anterior posterior axis specification GO:0009948 109 0.035
innate immune response GO:0045087 144 0.035
compound eye photoreceptor fate commitment GO:0001752 36 0.035
myosin filament assembly GO:0031034 5 0.035
Worm
negative regulation of cell death GO:0060548 81 0.035
positive regulation of phosphorus metabolic process GO:0010562 139 0.035
Fly
columnar cuboidal epithelial cell differentiation GO:0002065 256 0.034
negative regulation of gene expression epigenetic GO:0045814 77 0.034
chromosome segregation GO:0007059 157 0.034
eggshell chorion assembly GO:0007306 66 0.034
regulation of gliogenesis GO:0014013 11 0.034
Fly

Moe disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in fly and predicted with the fly functional network.

Disease DO term ID Size Probability Func Analog Org
disease of anatomical entity DOID:7 0 0.400
Human
cardiovascular system disease DOID:1287 0 0.400
disease of metabolism DOID:0014667 0 0.043
carbohydrate metabolism disease DOID:0050013 0 0.043
acquired metabolic disease DOID:0060158 0 0.043
myopathy DOID:423 0 0.035
muscular disease DOID:0080000 0 0.035
heart disease DOID:114 0 0.035
cardiomyopathy DOID:0050700 0 0.035
intrinsic cardiomyopathy DOID:0060036 0 0.035
musculoskeletal system disease DOID:17 0 0.035
muscle tissue disease DOID:66 0 0.035
glucose metabolism disease DOID:4194 0 0.034