Drosophila melanogaster

33 known processes

SK (Dmel_CG10706)

small conductance calcium-activated potassium channel

(Aliases: Dmel\CG10706,CG12733,dSK,BcDNA:GM01744,CG4179,CG10706)

SK biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
eye development GO:0001654 323 0.229
taxis GO:0042330 304 0.166
response to abiotic stimulus GO:0009628 341 0.163
growth GO:0040007 359 0.147
g protein coupled receptor signaling pathway GO:0007186 136 0.124
axonogenesis GO:0007409 290 0.116
regulation of cyclic nucleotide metabolic process GO:0030799 13 0.105
small molecule metabolic process GO:0044281 305 0.088
compound eye development GO:0048749 307 0.085
organonitrogen compound metabolic process GO:1901564 318 0.075
compound eye morphogenesis GO:0001745 249 0.066
intracellular signal transduction GO:0035556 300 0.066
sensory organ morphogenesis GO:0090596 260 0.066
regulation of cell differentiation GO:0045595 302 0.064
synapse organization GO:0050808 196 0.063
single organism biosynthetic process GO:0044711 206 0.062
regulation of catalytic activity GO:0050790 185 0.060
cell recognition GO:0008037 102 0.060
photoreceptor cell differentiation GO:0046530 170 0.057
regulation of localization GO:0032879 275 0.057
positive regulation of nitrogen compound metabolic process GO:0051173 354 0.057
nucleotide metabolic process GO:0009117 161 0.056
cell cell adhesion GO:0098609 26 0.054
macromolecular complex assembly GO:0065003 256 0.052
vesicle mediated transport GO:0016192 381 0.052
cardiovascular system development GO:0072358 82 0.051
positive regulation of phosphate metabolic process GO:0045937 139 0.050
eye morphogenesis GO:0048592 260 0.050
response to oxygen containing compound GO:1901700 200 0.050
purine ribonucleotide metabolic process GO:0009150 145 0.049
single organism behavior GO:0044708 391 0.049
protein complex assembly GO:0006461 200 0.049
nucleobase containing small molecule metabolic process GO:0055086 174 0.048
regulation of transport GO:0051049 181 0.048
regulation of phosphorus metabolic process GO:0051174 210 0.047
positive regulation of nucleobase containing compound metabolic process GO:0045935 332 0.047
ion transport GO:0006811 145 0.047
catabolic process GO:0009056 409 0.047
axon development GO:0061564 297 0.046
regulation of multicellular organismal development GO:2000026 414 0.046
organophosphate metabolic process GO:0019637 195 0.046
regulation of phosphate metabolic process GO:0019220 210 0.043
cell proliferation GO:0008283 299 0.041
positive regulation of biosynthetic process GO:0009891 316 0.041
regulation of cellular component biogenesis GO:0044087 201 0.041
purine containing compound metabolic process GO:0072521 155 0.041
developmental growth GO:0048589 280 0.040
sleep GO:0030431 49 0.040
phagocytosis GO:0006909 215 0.040
nucleoside phosphate metabolic process GO:0006753 162 0.040
eye photoreceptor cell differentiation GO:0001754 145 0.040
purine ribonucleotide biosynthetic process GO:0009152 28 0.040
protein complex biogenesis GO:0070271 201 0.040
cyclic nucleotide biosynthetic process GO:0009190 25 0.038
regulation of nervous system development GO:0051960 248 0.038
positive regulation of phosphorus metabolic process GO:0010562 139 0.038
biological adhesion GO:0022610 138 0.037
appendage development GO:0048736 401 0.037
carbohydrate derivative biosynthetic process GO:1901137 85 0.037
chemotaxis GO:0006935 249 0.036
ribonucleotide metabolic process GO:0009259 145 0.036
tube development GO:0035295 244 0.035
regulation of molecular function GO:0065009 217 0.035
carbohydrate derivative metabolic process GO:1901135 217 0.035
response to light stimulus GO:0009416 124 0.035
regulation of lipid storage GO:0010883 22 0.035
dendrite development GO:0016358 204 0.034
compound eye photoreceptor cell differentiation GO:0001751 140 0.034
locomotory behavior GO:0007626 176 0.033
establishment or maintenance of cell polarity GO:0007163 167 0.033
positive regulation of multicellular organismal process GO:0051240 143 0.032
response to organic substance GO:0010033 284 0.032
regulation of purine nucleotide metabolic process GO:1900542 62 0.032
nuclear division GO:0000280 332 0.031
cell adhesion GO:0007155 136 0.031
muscle structure development GO:0061061 224 0.030
positive regulation of signaling GO:0023056 243 0.030
adult behavior GO:0030534 137 0.030
synaptic transmission GO:0007268 288 0.030
positive regulation of purine nucleotide metabolic process GO:1900544 55 0.030
actin filament based process GO:0030029 220 0.030
neuromuscular junction development GO:0007528 149 0.030
circadian rhythm GO:0007623 105 0.029
ribose phosphate metabolic process GO:0019693 145 0.029
positive regulation of response to stimulus GO:0048584 323 0.029
cellular amine metabolic process GO:0044106 12 0.029
regulation of protein metabolic process GO:0051246 256 0.029
appendage morphogenesis GO:0035107 397 0.028
organic substance transport GO:0071702 257 0.028
purine containing compound biosynthetic process GO:0072522 30 0.028
adult locomotory behavior GO:0008344 76 0.028
embryonic axis specification GO:0000578 107 0.027
cellular amino acid metabolic process GO:0006520 61 0.027
regulation of nucleotide metabolic process GO:0006140 62 0.027
positive regulation of molecular function GO:0044093 136 0.027
negative regulation of biosynthetic process GO:0009890 277 0.027
cell maturation GO:0048469 144 0.027
response to other organism GO:0051707 293 0.026
ribose phosphate biosynthetic process GO:0046390 28 0.026
axis specification GO:0009798 167 0.026
response to lipopolysaccharide GO:0032496 4 0.026
organophosphate biosynthetic process GO:0090407 46 0.026
oocyte axis specification GO:0007309 108 0.026
positive regulation of macromolecule metabolic process GO:0010604 405 0.026
olfactory behavior GO:0042048 97 0.026
localization of cell GO:0051674 257 0.026
negative regulation of cellular biosynthetic process GO:0031327 277 0.025
positive regulation of cellular biosynthetic process GO:0031328 316 0.025
positive regulation of signal transduction GO:0009967 223 0.025
axon guidance GO:0007411 233 0.025
programmed cell death GO:0012501 257 0.025
nucleoside phosphate biosynthetic process GO:1901293 34 0.025
neuron fate commitment GO:0048663 50 0.025
regulation of anatomical structure morphogenesis GO:0022603 242 0.025
organic substance catabolic process GO:1901575 308 0.024
nucleotide biosynthetic process GO:0009165 34 0.024
developmental maturation GO:0021700 172 0.024
transcription from rna polymerase ii promoter GO:0006366 368 0.024
multi organism behavior GO:0051705 175 0.024
negative regulation of cell communication GO:0010648 223 0.024
positive regulation of cell communication GO:0010647 250 0.024
epithelial cell differentiation GO:0030855 322 0.024
cell death GO:0008219 279 0.024
chromosome organization GO:0051276 360 0.023
chemosensory behavior GO:0007635 106 0.023
regulation of mitotic cell cycle GO:0007346 190 0.023
cyclic purine nucleotide metabolic process GO:0052652 25 0.023
death GO:0016265 284 0.023
regulation of synapse structure and activity GO:0050803 128 0.023
endocytosis GO:0006897 310 0.023
homeostatic process GO:0042592 199 0.023
response to external biotic stimulus GO:0043207 293 0.023
cellular protein modification process GO:0006464 438 0.023
response to metal ion GO:0010038 23 0.022
ribonucleotide biosynthetic process GO:0009260 28 0.022
phosphorylation GO:0016310 294 0.022
apoptotic process GO:0006915 159 0.022
synapse assembly GO:0007416 143 0.022
epithelium migration GO:0090132 148 0.022
positive regulation of catalytic activity GO:0043085 118 0.021
organonitrogen compound biosynthetic process GO:1901566 117 0.021
cellular catabolic process GO:0044248 372 0.021
purine nucleotide biosynthetic process GO:0006164 29 0.021
mitotic nuclear division GO:0007067 213 0.021
purine nucleotide metabolic process GO:0006163 146 0.021
oxoacid metabolic process GO:0043436 103 0.021
actin cytoskeleton organization GO:0030036 206 0.021
regulation of cell development GO:0060284 215 0.021
eye photoreceptor cell development GO:0042462 81 0.021
camp biosynthetic process GO:0006171 17 0.021
regulation of cell morphogenesis GO:0022604 163 0.020
immune system process GO:0002376 347 0.020
tripartite regional subdivision GO:0007351 103 0.020
rna splicing GO:0008380 83 0.020
negative regulation of cellular metabolic process GO:0031324 382 0.020
cell cell adhesion via plasma membrane adhesion molecules GO:0098742 26 0.020
regulation of anatomical structure size GO:0090066 163 0.020
response to hypoxia GO:0001666 53 0.019
regulation of cell proliferation GO:0042127 163 0.019
dorsal ventral pattern formation GO:0009953 133 0.019
signal transduction by phosphorylation GO:0023014 107 0.019
imaginal disc derived appendage morphogenesis GO:0035114 395 0.019
striated muscle cell differentiation GO:0051146 90 0.019
carboxylic acid metabolic process GO:0019752 92 0.019
regulation of behavior GO:0050795 75 0.019
response to biotic stimulus GO:0009607 294 0.019
mapk cascade GO:0000165 107 0.019
heart development GO:0007507 82 0.019
positive regulation of developmental process GO:0051094 143 0.019
regulation of developmental growth GO:0048638 174 0.019
central nervous system development GO:0007417 201 0.019
establishment of protein localization GO:0045184 163 0.019
negative regulation of nitrogen compound metabolic process GO:0051172 265 0.019
regulation of phosphorylation GO:0042325 147 0.018
anterior posterior axis specification embryo GO:0008595 103 0.018
regulation of mapk cascade GO:0043408 92 0.018
response to oxygen levels GO:0070482 59 0.018
protein phosphorylation GO:0006468 169 0.018
regulation of neurogenesis GO:0050767 158 0.018
transmembrane transport GO:0055085 139 0.018
positive regulation of nucleotide metabolic process GO:0045981 55 0.018
regulation of cellular amine metabolic process GO:0033238 3 0.018
cellular response to lipopolysaccharide GO:0071222 3 0.018
dendrite morphogenesis GO:0048813 199 0.018
negative regulation of signaling GO:0023057 219 0.018
protein heterooligomerization GO:0051291 4 0.018
post embryonic appendage morphogenesis GO:0035120 385 0.018
cell growth GO:0016049 108 0.018
regulation of cell shape GO:0008360 113 0.017
wing disc morphogenesis GO:0007472 344 0.017
circulatory system development GO:0072359 82 0.017
negative regulation of rna biosynthetic process GO:1902679 240 0.017
regulation of cellular ketone metabolic process GO:0010565 3 0.017
neuron projection guidance GO:0097485 241 0.017
membrane organization GO:0061024 112 0.017
embryonic morphogenesis GO:0048598 206 0.017
organophosphate catabolic process GO:0046434 112 0.017
regulation of immune system process GO:0002682 176 0.017
neuron recognition GO:0008038 101 0.016
organelle fission GO:0048285 340 0.016
cellular macromolecule localization GO:0070727 220 0.016
cell motility GO:0048870 251 0.016
regulation of intracellular signal transduction GO:1902531 236 0.016
compound eye photoreceptor development GO:0042051 78 0.016
regulation of cell cycle GO:0051726 291 0.016
negative regulation of gene expression GO:0010629 387 0.016
amine metabolic process GO:0009308 12 0.016
respiratory system development GO:0060541 213 0.016
establishment of localization in cell GO:0051649 402 0.016
regionalization GO:0003002 416 0.016
positive regulation of hydrolase activity GO:0051345 78 0.016
maintenance of location GO:0051235 73 0.016
protein modification process GO:0036211 438 0.016
oocyte development GO:0048599 124 0.016
regulation of growth GO:0040008 233 0.016
imaginal disc derived wing morphogenesis GO:0007476 337 0.016
response to decreased oxygen levels GO:0036293 58 0.016
tube morphogenesis GO:0035239 191 0.016
protein localization GO:0008104 284 0.016
positive regulation of gene expression GO:0010628 290 0.015
photoreceptor cell fate commitment GO:0046552 41 0.015
regulation of cellular localization GO:0060341 136 0.015
eye photoreceptor cell fate commitment GO:0042706 37 0.015
epithelial cell migration GO:0010631 148 0.015
regulation of rna splicing GO:0043484 69 0.015
regulation of transcription from rna polymerase ii promoter GO:0006357 378 0.015
positive regulation of transcription from rna polymerase ii promoter GO:0045944 204 0.015
neuron projection extension GO:1990138 32 0.015
regulation of organelle organization GO:0033043 196 0.015
positive regulation of cell differentiation GO:0045597 64 0.015
cellular response to biotic stimulus GO:0071216 4 0.015
anterior posterior axis specification GO:0009948 109 0.015
rhythmic process GO:0048511 106 0.014
response to radiation GO:0009314 155 0.014
regulation of neuron differentiation GO:0045664 103 0.014
mrna processing GO:0006397 104 0.014
mrna splicing via spliceosome GO:0000398 73 0.014
intracellular mrna localization GO:0008298 66 0.014
oocyte anterior posterior axis specification GO:0007314 72 0.014
intracellular mrna localization involved in anterior posterior axis specification GO:0060811 53 0.014
muscle cell differentiation GO:0042692 103 0.014
negative regulation of nucleobase containing compound metabolic process GO:0045934 261 0.014
imaginal disc derived appendage development GO:0048737 399 0.014
cytoplasm organization GO:0007028 64 0.014
developmental growth involved in morphogenesis GO:0060560 65 0.014
cellular response to organic substance GO:0071310 132 0.014
positive regulation of transcription dna templated GO:0045893 266 0.014
defense response GO:0006952 300 0.014
regulation of cell cycle process GO:0010564 181 0.014
photoreceptor cell development GO:0042461 96 0.013
secretion by cell GO:0032940 101 0.013
response to bacterium GO:0009617 198 0.013
forebrain development GO:0030900 2 0.013
imaginal disc pattern formation GO:0007447 91 0.013
positive regulation of sequestering of triglyceride GO:0010890 1 0.013
regulation of immune response GO:0050776 118 0.013
detection of stimulus GO:0051606 156 0.013
single organism catabolic process GO:0044712 228 0.013
organonitrogen compound catabolic process GO:1901565 128 0.013
sterol homeostasis GO:0055092 4 0.013
actin filament organization GO:0007015 126 0.013
positive regulation of cellular component organization GO:0051130 156 0.013
positive regulation of cellular protein metabolic process GO:0032270 118 0.013
developmental cell growth GO:0048588 52 0.013
regulation of cellular protein metabolic process GO:0032268 243 0.013
regulation of excitatory postsynaptic membrane potential GO:0060079 3 0.013
wing disc pattern formation GO:0035222 66 0.013
androgen metabolic process GO:0008209 1 0.013
rna processing GO:0006396 147 0.013
positive regulation of transport GO:0051050 92 0.013
response to endogenous stimulus GO:0009719 119 0.013
regulation of vesicle mediated transport GO:0060627 59 0.013
rna splicing via transesterification reactions with bulged adenosine as nucleophile GO:0000377 73 0.013
trachea development GO:0060438 29 0.013
neurological system process GO:0050877 358 0.012
response to organic cyclic compound GO:0014070 89 0.012
cellular ketone metabolic process GO:0042180 24 0.012
positive regulation of intracellular signal transduction GO:1902533 116 0.012
embryo development ending in birth or egg hatching GO:0009792 152 0.012
cholesterol transport GO:0030301 2 0.012
positive regulation of phosphorylation GO:0042327 87 0.012
regulation of synaptic transmission GO:0050804 69 0.012
negative regulation of macromolecule biosynthetic process GO:0010558 270 0.012
inorganic cation transmembrane transport GO:0098662 61 0.012
morphogenesis of an epithelium GO:0002009 276 0.012
single organism membrane organization GO:0044802 93 0.012
positive regulation of nervous system development GO:0051962 69 0.012
cation transport GO:0006812 110 0.012
cation transmembrane transport GO:0098655 88 0.012
erk1 and erk2 cascade GO:0070371 39 0.012
negative regulation of cellular macromolecule biosynthetic process GO:2000113 267 0.012
regulation of alternative mrna splicing via spliceosome GO:0000381 60 0.012
ameboidal type cell migration GO:0001667 151 0.012
positive regulation of cell migration GO:0030335 2 0.012
regulation of cell projection organization GO:0031344 92 0.012
cholesterol homeostasis GO:0042632 3 0.012
negative regulation of response to stimulus GO:0048585 258 0.011
regulation of gene expression epigenetic GO:0040029 128 0.011
neural precursor cell proliferation GO:0061351 75 0.011
neuropeptide signaling pathway GO:0007218 45 0.011
oocyte construction GO:0007308 112 0.011
axon extension GO:0048675 32 0.011
lipid biosynthetic process GO:0008610 46 0.011
response to organonitrogen compound GO:0010243 75 0.011
enzyme linked receptor protein signaling pathway GO:0007167 179 0.011
regulation of cell death GO:0010941 173 0.011
single organism cellular localization GO:1902580 180 0.011
lipid metabolic process GO:0006629 121 0.011
gtp catabolic process GO:0006184 72 0.011
r7 cell differentiation GO:0045466 43 0.011
organic cyclic compound catabolic process GO:1901361 168 0.011
regulation of camp metabolic process GO:0030814 12 0.011
anatomical structure homeostasis GO:0060249 97 0.011
cell migration GO:0016477 238 0.011
rna splicing via transesterification reactions GO:0000375 73 0.011
cell division GO:0051301 248 0.011
purine ribonucleoside metabolic process GO:0046128 127 0.011
embryonic development via the syncytial blastoderm GO:0001700 148 0.011
protein transport GO:0015031 155 0.011
circadian behavior GO:0048512 76 0.011
muscle organ development GO:0007517 127 0.011
positive regulation of cell motility GO:2000147 3 0.011
positive regulation of cell development GO:0010720 61 0.011
neutral lipid biosynthetic process GO:0046460 2 0.011
proteolysis GO:0006508 192 0.011
positive regulation of purine nucleotide biosynthetic process GO:1900373 10 0.011
inorganic ion transmembrane transport GO:0098660 73 0.011
transmembrane receptor protein tyrosine kinase signaling pathway GO:0007169 116 0.011
camp metabolic process GO:0046058 19 0.010
regulation of nucleotide biosynthetic process GO:0030808 14 0.010
organic acid metabolic process GO:0006082 103 0.010
cellular response to molecule of bacterial origin GO:0071219 3 0.010
rhythmic behavior GO:0007622 76 0.010
purine nucleoside triphosphate metabolic process GO:0009144 119 0.010
regulation of synapse organization GO:0050807 110 0.010
lipid localization GO:0010876 54 0.010
embryonic pattern specification GO:0009880 174 0.010
guanosine containing compound catabolic process GO:1901069 74 0.010
mating GO:0007618 120 0.010

SK disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in fly and predicted with the fly functional network.

Disease DO term ID Size Probability Func Analog Org
disease of anatomical entity DOID:7 0 0.051
disease of metabolism DOID:0014667 0 0.020
cardiovascular system disease DOID:1287 0 0.019
hair disease DOID:421 0 0.013
integumentary system disease DOID:16 0 0.013
hypotrichosis DOID:4535 0 0.011
acquired metabolic disease DOID:0060158 0 0.011
nervous system disease DOID:863 0 0.011