Drosophila melanogaster

39 known processes

CG18271 (Dmel_CG18271)

CG18271 gene product from transcript CG18271-RB

(Aliases: SLX1,Dmel\CG18271)

CG18271 biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
reciprocal meiotic recombination GO:0007131 19 0.284
cell cycle phase transition GO:0044770 140 0.165
mitotic cell cycle phase transition GO:0044772 138 0.148
cellular response to dna damage stimulus GO:0006974 223 0.141
negative regulation of rna biosynthetic process GO:1902679 240 0.120
mitotic dna integrity checkpoint GO:0044774 75 0.100
chorion containing eggshell formation GO:0007304 105 0.099
chromosome segregation GO:0007059 157 0.098
mitotic g2 m transition checkpoint GO:0044818 70 0.098
negative regulation of gene expression GO:0010629 387 0.095
dna recombination GO:0006310 32 0.091
reciprocal dna recombination GO:0035825 19 0.090
meiotic cell cycle process GO:1903046 132 0.089
negative regulation of cellular metabolic process GO:0031324 382 0.088
regulation of mitotic cell cycle GO:0007346 190 0.088
dna repair GO:0006281 54 0.088
mitotic dna damage checkpoint GO:0044773 74 0.082
negative regulation of transcription dna templated GO:0045892 237 0.081
regulation of cell cycle process GO:0010564 181 0.075
response to abiotic stimulus GO:0009628 341 0.072
negative regulation of mitotic cell cycle GO:0045930 109 0.071
dna integrity checkpoint GO:0031570 81 0.066
regulation of cell cycle GO:0051726 291 0.065
negative regulation of macromolecule biosynthetic process GO:0010558 270 0.064
columnar cuboidal epithelial cell development GO:0002066 249 0.063
meiosis i GO:0007127 59 0.062
negative regulation of cell cycle process GO:0010948 109 0.060
negative regulation of cellular macromolecule biosynthetic process GO:2000113 267 0.058
dna damage checkpoint GO:0000077 78 0.058
axis specification GO:0009798 167 0.058
chromosome organization GO:0051276 360 0.057
negative regulation of cellular biosynthetic process GO:0031327 277 0.057
regulation of mitotic cell cycle phase transition GO:1901990 130 0.057
negative regulation of biosynthetic process GO:0009890 277 0.055
negative regulation of cell cycle GO:0045786 116 0.055
negative regulation of nucleic acid templated transcription GO:1903507 240 0.054
meiotic chromosome segregation GO:0045132 59 0.054
mitotic g2 dna damage checkpoint GO:0007095 69 0.053
phosphorylation GO:0016310 294 0.050
response to radiation GO:0009314 155 0.048
g2 dna damage checkpoint GO:0031572 69 0.045
organonitrogen compound metabolic process GO:1901564 318 0.044
body morphogenesis GO:0010171 2 0.044
dna metabolic process GO:0006259 227 0.043
meiotic nuclear division GO:0007126 151 0.043
negative regulation of nitrogen compound metabolic process GO:0051172 265 0.041
wing disc morphogenesis GO:0007472 344 0.041
recombinational repair GO:0000725 13 0.040
small molecule metabolic process GO:0044281 305 0.040
double strand break repair via homologous recombination GO:0000724 13 0.040
chromosome separation GO:0051304 42 0.039
negative regulation of cell cycle phase transition GO:1901988 103 0.038
cellular component assembly involved in morphogenesis GO:0010927 151 0.038
regulation of cell cycle phase transition GO:1901987 130 0.038
negative regulation of mitotic cell cycle phase transition GO:1901991 103 0.036
nuclear division GO:0000280 332 0.035
epithelial cell development GO:0002064 274 0.034
cellular response to radiation GO:0071478 52 0.034
regulation of cell death GO:0010941 173 0.034
organelle fission GO:0048285 340 0.034
negative regulation of cell communication GO:0010648 223 0.034
positive regulation of cellular biosynthetic process GO:0031328 316 0.033
positive regulation of macromolecule biosynthetic process GO:0010557 283 0.033
cellular response to abiotic stimulus GO:0071214 58 0.032
vesicle mediated transport GO:0016192 381 0.031
cellular protein modification process GO:0006464 438 0.031
gene silencing GO:0016458 138 0.031
positive regulation of response to stimulus GO:0048584 323 0.031
regulation of protein metabolic process GO:0051246 256 0.031
cellular response to organic substance GO:0071310 132 0.031
organic substance catabolic process GO:1901575 308 0.030
transcription from rna polymerase ii promoter GO:0006366 368 0.030
negative regulation of nucleobase containing compound metabolic process GO:0045934 261 0.030
programmed cell death GO:0012501 257 0.029
cell death GO:0008219 279 0.029
chromatin organization GO:0006325 207 0.028
negative regulation of rna metabolic process GO:0051253 251 0.028
regulation of transcription from rna polymerase ii promoter GO:0006357 378 0.028
axonogenesis GO:0007409 290 0.028
imaginal disc derived wing morphogenesis GO:0007476 337 0.028
dorsal ventral axis specification GO:0009950 66 0.027
imaginal disc derived appendage development GO:0048737 399 0.027
neurological system process GO:0050877 358 0.026
cell cycle checkpoint GO:0000075 95 0.026
positive regulation of signal transduction GO:0009967 223 0.025
cellular catabolic process GO:0044248 372 0.025
mapk cascade GO:0000165 107 0.025
meiotic cell cycle GO:0051321 171 0.025
regulation of programmed cell death GO:0043067 152 0.025
axon development GO:0061564 297 0.025
negative regulation of organelle organization GO:0010639 56 0.025
cell proliferation GO:0008283 299 0.025
response to organic substance GO:0010033 284 0.025
regulation of cellular amine metabolic process GO:0033238 3 0.024
regulation of intracellular signal transduction GO:1902531 236 0.024
dorsal ventral pattern formation GO:0009953 133 0.024
organic cyclic compound catabolic process GO:1901361 168 0.024
positive regulation of macromolecule metabolic process GO:0010604 405 0.024
macromolecule catabolic process GO:0009057 161 0.024
cell motility GO:0048870 251 0.024
positive regulation of intracellular signal transduction GO:1902533 116 0.024
negative regulation of signaling GO:0023057 219 0.024
regulation of response to stress GO:0080134 200 0.023
amine metabolic process GO:0009308 12 0.023
regionalization GO:0003002 416 0.023
regulation of gene expression epigenetic GO:0040029 128 0.023
regulation of phosphorylation GO:0042325 147 0.023
appendage development GO:0048736 401 0.023
protein modification process GO:0036211 438 0.023
positive regulation of nucleic acid templated transcription GO:1903508 266 0.023
positive regulation of cell communication GO:0010647 250 0.023
regulation of apoptotic process GO:0042981 130 0.022
single organism biosynthetic process GO:0044711 206 0.022
positive regulation of biosynthetic process GO:0009891 316 0.022
regulation of cellular ketone metabolic process GO:0010565 3 0.022
single organism intracellular transport GO:1902582 207 0.022
positive regulation of signaling GO:0023056 243 0.022
cell migration GO:0016477 238 0.021
positive regulation of gene expression GO:0010628 290 0.021
regulation of cellular protein metabolic process GO:0032268 243 0.021
negative regulation of signal transduction GO:0009968 206 0.021
mitotic cell cycle checkpoint GO:0007093 88 0.021
regulation of multicellular organismal development GO:2000026 414 0.021
covalent chromatin modification GO:0016569 106 0.021
catabolic process GO:0009056 409 0.021
regulation of phosphorus metabolic process GO:0051174 210 0.021
appendage morphogenesis GO:0035107 397 0.021
anterior posterior pattern specification GO:0009952 136 0.021
columnar cuboidal epithelial cell differentiation GO:0002065 256 0.020
cellular ketone metabolic process GO:0042180 24 0.020
immune response GO:0006955 246 0.020
apoptotic process GO:0006915 159 0.020
oxoacid metabolic process GO:0043436 103 0.020
compound eye development GO:0048749 307 0.020
morphogenesis of an epithelium GO:0002009 276 0.020
positive regulation of transcription dna templated GO:0045893 266 0.020
negative regulation of gene expression epigenetic GO:0045814 77 0.020
positive regulation of rna biosynthetic process GO:1902680 266 0.019
chromatin modification GO:0016568 147 0.019
imaginal disc derived appendage morphogenesis GO:0035114 395 0.019
protein maturation GO:0051604 71 0.019
rna localization GO:0006403 115 0.019
organonitrogen compound catabolic process GO:1901565 128 0.019
single organism catabolic process GO:0044712 228 0.019
double strand break repair GO:0006302 26 0.019
cellular amine metabolic process GO:0044106 12 0.019
developmental growth GO:0048589 280 0.019
cellular nitrogen compound catabolic process GO:0044270 165 0.019
multicellular organismal aging GO:0010259 140 0.019
mitotic nuclear division GO:0007067 213 0.018
connective tissue development GO:0061448 3 0.018
negative regulation of response to stimulus GO:0048585 258 0.018
carboxylic acid metabolic process GO:0019752 92 0.018
localization of cell GO:0051674 257 0.018
post embryonic appendage morphogenesis GO:0035120 385 0.018
ovarian follicle cell development GO:0030707 248 0.018
cellular amino acid metabolic process GO:0006520 61 0.018
nucleoside triphosphate catabolic process GO:0009143 108 0.018
mitotic sister chromatid segregation GO:0000070 87 0.018
response to ionizing radiation GO:0010212 32 0.018
cell division GO:0051301 248 0.018
growth GO:0040007 359 0.018
histone modification GO:0016570 106 0.018
dna conformation change GO:0071103 105 0.018
medium chain fatty acid metabolic process GO:0051791 1 0.018
regulation of anatomical structure size GO:0090066 163 0.017
chromatin silencing GO:0006342 76 0.017
protein phosphorylation GO:0006468 169 0.017
death GO:0016265 284 0.017
organic acid metabolic process GO:0006082 103 0.017
germarium derived egg chamber formation GO:0007293 101 0.017
cellular response to chemical stimulus GO:0070887 199 0.017
negative regulation of cellular component organization GO:0051129 108 0.017
toxin metabolic process GO:0009404 2 0.017
anterior posterior axis specification GO:0009948 109 0.017
cellular macromolecule localization GO:0070727 220 0.017
response to oxygen containing compound GO:1901700 200 0.017
nucleoside phosphate metabolic process GO:0006753 162 0.016
open tracheal system development GO:0007424 204 0.016
regulation of cell differentiation GO:0045595 302 0.016
response to light stimulus GO:0009416 124 0.016
nucleobase containing compound catabolic process GO:0034655 165 0.016
cell recognition GO:0008037 102 0.016
eggshell formation GO:0030703 105 0.016
regulation of immune system process GO:0002682 176 0.016
vitamin metabolic process GO:0006766 2 0.016
negative regulation of cell death GO:0060548 81 0.016
sister chromatid segregation GO:0000819 92 0.016
intracellular signal transduction GO:0035556 300 0.016
regulation of cellular component size GO:0032535 98 0.016
mitotic spindle organization GO:0007052 220 0.016
positive regulation of nucleobase containing compound metabolic process GO:0045935 332 0.016
endocytosis GO:0006897 310 0.015
gland development GO:0048732 191 0.015
protein complex biogenesis GO:0070271 201 0.015
nucleotide excision repair GO:0006289 8 0.015
negative regulation of programmed cell death GO:0043069 72 0.015
anion homeostasis GO:0055081 3 0.015
regulation of cellular response to stress GO:0080135 89 0.015
regulation of molecular function GO:0065009 217 0.015
cellular macromolecular complex assembly GO:0034622 153 0.015
positive regulation of nitrogen compound metabolic process GO:0051173 354 0.014
transmembrane receptor protein tyrosine kinase signaling pathway GO:0007169 116 0.014
immune system process GO:0002376 347 0.014
male gamete generation GO:0048232 201 0.014
regulation of phosphate metabolic process GO:0019220 210 0.014
forebrain development GO:0030900 2 0.014
purine containing compound metabolic process GO:0072521 155 0.014
peptidyl amino acid modification GO:0018193 105 0.014
response to oxidative stress GO:0006979 86 0.014
protein complex assembly GO:0006461 200 0.014
negative regulation of apoptotic process GO:0043066 63 0.014
protein localization GO:0008104 284 0.014
rna processing GO:0006396 147 0.014
regulation of cell development GO:0060284 215 0.014
establishment of localization in cell GO:0051649 402 0.014
regulation of cellular amino acid metabolic process GO:0006521 0 0.014
ras protein signal transduction GO:0007265 88 0.014
enzyme linked receptor protein signaling pathway GO:0007167 179 0.014
phagocytosis GO:0006909 215 0.014
macromolecular complex assembly GO:0065003 256 0.014
negative regulation of developmental process GO:0051093 201 0.013
regulation of notch signaling pathway GO:0008593 100 0.013
protein localization to organelle GO:0033365 82 0.013
carbohydrate derivative metabolic process GO:1901135 217 0.013
embryo development ending in birth or egg hatching GO:0009792 152 0.013
tissue morphogenesis GO:0048729 297 0.013
regulation of rna splicing GO:0043484 69 0.013
nucleobase containing small molecule metabolic process GO:0055086 174 0.013
signal transduction by phosphorylation GO:0023014 107 0.013
positive regulation of mitotic cell cycle GO:0045931 34 0.013
regulation of anatomical structure morphogenesis GO:0022603 242 0.013
proteolysis GO:0006508 192 0.013
response to other organism GO:0051707 293 0.013
regulation of proteolysis GO:0030162 87 0.012
regulation of cellular catabolic process GO:0031329 157 0.012
sex differentiation GO:0007548 81 0.012
eye development GO:0001654 323 0.012
regulation of neurogenesis GO:0050767 158 0.012
positive regulation of transcription from rna polymerase ii promoter GO:0045944 204 0.012
compound eye morphogenesis GO:0001745 249 0.012
regulation of gene silencing GO:0060968 63 0.012
autophagy GO:0006914 108 0.012
embryonic axis specification GO:0000578 107 0.012
organophosphate metabolic process GO:0019637 195 0.012
purine ribonucleoside catabolic process GO:0046130 112 0.012
single organism cellular localization GO:1902580 180 0.012
response to endogenous stimulus GO:0009719 119 0.012
organelle assembly GO:0070925 198 0.012
ribonucleotide metabolic process GO:0009259 145 0.012
ribonucleoside catabolic process GO:0042454 112 0.012
ameboidal type cell migration GO:0001667 151 0.012
hindbrain development GO:0030902 2 0.012
purine nucleotide metabolic process GO:0006163 146 0.012
developmental programmed cell death GO:0010623 138 0.012
response to uv GO:0009411 24 0.011
small gtpase mediated signal transduction GO:0007264 88 0.011
negative regulation of multicellular organismal process GO:0051241 142 0.011
blastoderm segmentation GO:0007350 159 0.011
nucleotide metabolic process GO:0009117 161 0.011
compound eye photoreceptor cell differentiation GO:0001751 140 0.011
regulation of cell division GO:0051302 72 0.011
cell projection assembly GO:0030031 94 0.011
spindle organization GO:0007051 253 0.011
regulation of cytoskeleton organization GO:0051493 89 0.011
regulation of organelle organization GO:0033043 196 0.011
organic substance transport GO:0071702 257 0.011
negative regulation of cell differentiation GO:0045596 143 0.011
spermatogenesis GO:0007283 200 0.011
regulation of organ morphogenesis GO:2000027 78 0.011
wound healing GO:0042060 75 0.011
determination of adult lifespan GO:0008340 137 0.011
neuron projection guidance GO:0097485 241 0.011
positive regulation of catabolic process GO:0009896 105 0.011
eggshell chorion assembly GO:0007306 66 0.011
taxis GO:0042330 304 0.011
aromatic compound catabolic process GO:0019439 166 0.011
purine ribonucleotide metabolic process GO:0009150 145 0.011
alternative mrna splicing via spliceosome GO:0000380 60 0.011
positive regulation of rna metabolic process GO:0051254 271 0.011
regulation of nervous system development GO:0051960 248 0.010
synaptic transmission GO:0007268 288 0.010
nephron development GO:0072006 3 0.010
compound eye photoreceptor development GO:0042051 78 0.010
proteasome mediated ubiquitin dependent protein catabolic process GO:0043161 54 0.010
ribonucleoside monophosphate metabolic process GO:0009161 51 0.010
camera type eye development GO:0043010 4 0.010
sterol homeostasis GO:0055092 4 0.010
intracellular transport GO:0046907 228 0.010
negative regulation of erk1 and erk2 cascade GO:0070373 3 0.010
kidney development GO:0001822 3 0.010
rna splicing GO:0008380 83 0.010
salivary gland morphogenesis GO:0007435 145 0.010
negative regulation of nervous system development GO:0051961 92 0.010
mitotic recombination GO:0006312 2 0.010
regulation of protein modification process GO:0031399 112 0.010
positive regulation of cellular component organization GO:0051130 156 0.010
actin filament organization GO:0007015 126 0.010
sensory organ morphogenesis GO:0090596 260 0.010
cilium morphogenesis GO:0060271 39 0.010
organophosphate catabolic process GO:0046434 112 0.010
dna biosynthetic process GO:0071897 24 0.010
regulation of localization GO:0032879 275 0.010
cellular macromolecule catabolic process GO:0044265 136 0.010
salivary gland histolysis GO:0035070 88 0.010
regulation of cell morphogenesis GO:0022604 163 0.010

CG18271 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in fly and predicted with the fly functional network.

Disease DO term ID Size Probability Func Analog Org
disease of anatomical entity DOID:7 0 0.052
disease of metabolism DOID:0014667 0 0.023
inherited metabolic disorder DOID:655 0 0.017
cancer DOID:162 0 0.014
disease of cellular proliferation DOID:14566 0 0.014
organ system cancer DOID:0050686 0 0.014
cardiovascular system disease DOID:1287 0 0.013
nervous system disease DOID:863 0 0.012