Drosophila melanogaster

160 known processes

RacGAP84C (Dmel_CG2595)

CG2595 gene product from transcript CG2595-RA

(Aliases: GAP84C,rnprot,rnprot1.7,rnracGap,rnRacGAP,racGAP,rnracGAP,rnGAP,Dmel\CG2595,P1.7,CG2595,RhoGAP-84C8,rnRac-GAP,rnRacGap,RacGAP(84C))

RacGAP84C biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
tissue morphogenesis GO:0048729 297 0.414
morphogenesis of an epithelium GO:0002009 276 0.298
negative regulation of cellular metabolic process GO:0031324 382 0.295
negative regulation of biosynthetic process GO:0009890 277 0.218
compound eye development GO:0048749 307 0.166
negative regulation of rna metabolic process GO:0051253 251 0.152
negative regulation of nucleobase containing compound metabolic process GO:0045934 261 0.150
negative regulation of gene expression GO:0010629 387 0.148
negative regulation of cellular biosynthetic process GO:0031327 277 0.113
compound eye morphogenesis GO:0001745 249 0.108
negative regulation of nitrogen compound metabolic process GO:0051172 265 0.107
localization of cell GO:0051674 257 0.105
appendage development GO:0048736 401 0.105
tube morphogenesis GO:0035239 191 0.104
negative regulation of rna biosynthetic process GO:1902679 240 0.103
imaginal disc derived appendage development GO:0048737 399 0.096
neurological system process GO:0050877 358 0.093
regionalization GO:0003002 416 0.092
cell division GO:0051301 248 0.089
Fly
wing disc morphogenesis GO:0007472 344 0.089
negative regulation of transcription from rna polymerase ii promoter GO:0000122 119 0.089
imaginal disc derived appendage morphogenesis GO:0035114 395 0.087
negative regulation of transcription dna templated GO:0045892 237 0.086
cell cell signaling involved in cell fate commitment GO:0045168 210 0.085
intracellular signal transduction GO:0035556 300 0.081
tube development GO:0035295 244 0.077
protein maturation GO:0051604 71 0.077
dorsal closure GO:0007391 79 0.077
central nervous system development GO:0007417 201 0.074
protein localization GO:0008104 284 0.073
Fly
muscle organ development GO:0007517 127 0.073
imaginal disc derived wing morphogenesis GO:0007476 337 0.072
post embryonic appendage morphogenesis GO:0035120 385 0.070
developmental growth GO:0048589 280 0.069
growth GO:0040007 359 0.067
negative regulation of nucleic acid templated transcription GO:1903507 240 0.064
actin filament based process GO:0030029 220 0.064
positive regulation of response to stimulus GO:0048584 323 0.063
eye morphogenesis GO:0048592 260 0.063
epithelial cell development GO:0002064 274 0.062
transcription from rna polymerase ii promoter GO:0006366 368 0.062
negative regulation of cell cycle process GO:0010948 109 0.061
negative regulation of macromolecule biosynthetic process GO:0010558 270 0.061
muscle structure development GO:0061061 224 0.061
Fly
regulation of transcription from rna polymerase ii promoter GO:0006357 378 0.060
kidney epithelium development GO:0072073 3 0.060
regulation of mapk cascade GO:0043408 92 0.060
establishment of localization in cell GO:0051649 402 0.058
negative regulation of mitotic cell cycle GO:0045930 109 0.057
positive regulation of cell communication GO:0010647 250 0.057
embryo development ending in birth or egg hatching GO:0009792 152 0.056
male gamete generation GO:0048232 201 0.052
regulation of cell cycle GO:0051726 291 0.052
kidney morphogenesis GO:0060993 3 0.052
morphogenesis of embryonic epithelium GO:0016331 94 0.052
regulation of cell death GO:0010941 173 0.052
regulation of localization GO:0032879 275 0.051
actin cytoskeleton organization GO:0030036 206 0.050
positive regulation of transcription dna templated GO:0045893 266 0.050
columnar cuboidal epithelial cell differentiation GO:0002065 256 0.050
regulation of transport GO:0051049 181 0.050
response to other organism GO:0051707 293 0.049
spermatogenesis GO:0007283 200 0.049
lateral inhibition GO:0046331 206 0.049
small molecule metabolic process GO:0044281 305 0.048
immune system process GO:0002376 347 0.048
negative regulation of cell communication GO:0010648 223 0.047
Fly
regulation of phosphorus metabolic process GO:0051174 210 0.046
dorsal ventral pattern formation GO:0009953 133 0.046
regulation of cell cycle process GO:0010564 181 0.045
regulation of molecular function GO:0065009 217 0.044
positive regulation of signal transduction GO:0009967 223 0.042
immune response GO:0006955 246 0.042
negative regulation of cellular macromolecule biosynthetic process GO:2000113 267 0.042
appendage morphogenesis GO:0035107 397 0.041
intracellular transport GO:0046907 228 0.041
ovarian follicle cell development GO:0030707 248 0.040
brain development GO:0007420 120 0.039
peptidyl threonine phosphorylation GO:0018107 2 0.039
regulation of intracellular signal transduction GO:1902531 236 0.038
regulation of nervous system development GO:0051960 248 0.038
negative regulation of signaling GO:0023057 219 0.038
Fly
single organism cellular localization GO:1902580 180 0.037
eye development GO:0001654 323 0.037
homeostatic process GO:0042592 199 0.037
cell proliferation GO:0008283 299 0.037
Mouse Fly
mapk cascade GO:0000165 107 0.036
defense response GO:0006952 300 0.036
embryonic morphogenesis GO:0048598 206 0.036
regulation of catalytic activity GO:0050790 185 0.036
cell migration GO:0016477 238 0.036
axis specification GO:0009798 167 0.035
signal transduction by phosphorylation GO:0023014 107 0.035
embryonic development via the syncytial blastoderm GO:0001700 148 0.035
regulation of apoptotic process GO:0042981 130 0.034
stress activated mapk cascade GO:0051403 52 0.034
learning or memory GO:0007611 141 0.033
columnar cuboidal epithelial cell development GO:0002066 249 0.033
endocytosis GO:0006897 310 0.033
phosphorylation GO:0016310 294 0.033
purine ribonucleotide metabolic process GO:0009150 145 0.033
hindbrain development GO:0030902 2 0.032
vesicle mediated transport GO:0016192 381 0.032
positive regulation of immune system process GO:0002684 68 0.032
epithelial tube morphogenesis GO:0060562 88 0.032
establishment of tissue polarity GO:0007164 87 0.031
negative regulation of cell cycle GO:0045786 116 0.031
regulation of response to stress GO:0080134 200 0.031
negative regulation of organelle organization GO:0010639 56 0.031
exocrine system development GO:0035272 162 0.030
positive regulation of nucleic acid templated transcription GO:1903508 266 0.030
regulation of cellular localization GO:0060341 136 0.030
mitotic nuclear division GO:0007067 213 0.029
Fly
digestive tract morphogenesis GO:0048546 127 0.029
gland morphogenesis GO:0022612 145 0.029
stress activated protein kinase signaling cascade GO:0031098 55 0.029
cell motility GO:0048870 251 0.029
single organism biosynthetic process GO:0044711 206 0.028
forebrain development GO:0030900 2 0.028
lipid metabolic process GO:0006629 121 0.028
protein processing GO:0016485 68 0.028
anterior posterior pattern specification GO:0009952 136 0.028
regulation of mitosis GO:0007088 56 0.028
morphogenesis of a polarized epithelium GO:0001738 93 0.028
detection of stimulus GO:0051606 156 0.028
axonogenesis GO:0007409 290 0.027
immune response activating signal transduction GO:0002757 2 0.027
positive regulation of macromolecule biosynthetic process GO:0010557 283 0.027
protein complex biogenesis GO:0070271 201 0.027
Fly
organic hydroxy compound metabolic process GO:1901615 83 0.027
regulation of phosphate metabolic process GO:0019220 210 0.026
protein polymerization GO:0051258 42 0.026
protein modification process GO:0036211 438 0.026
regulation of programmed cell death GO:0043067 152 0.026
epithelial cell differentiation GO:0030855 322 0.025
organic substance transport GO:0071702 257 0.025
death GO:0016265 284 0.025
tissue migration GO:0090130 155 0.025
positive regulation of phosphate metabolic process GO:0045937 139 0.024
photoreceptor cell differentiation GO:0046530 170 0.024
regulation of nuclear division GO:0051783 58 0.024
transmembrane receptor protein tyrosine kinase signaling pathway GO:0007169 116 0.024
head involution GO:0008258 35 0.024
regulation of cellular ketone metabolic process GO:0010565 3 0.023
connective tissue development GO:0061448 3 0.023
neuromuscular junction development GO:0007528 149 0.023
positive regulation of macromolecule metabolic process GO:0010604 405 0.023
purine containing compound metabolic process GO:0072521 155 0.023
chromosome organization GO:0051276 360 0.023
nephron tubule development GO:0072080 3 0.023
tissue homeostasis GO:0001894 36 0.022
regulation of stress activated mapk cascade GO:0032872 41 0.022
response to external biotic stimulus GO:0043207 293 0.022
positive regulation of cellular amine metabolic process GO:0033240 0 0.022
digestive tract development GO:0048565 149 0.022
myotube differentiation GO:0014902 46 0.022
cytoplasmic transport GO:0016482 130 0.022
cellular macromolecule catabolic process GO:0044265 136 0.022
positive regulation of signaling GO:0023056 243 0.022
phosphate ion transport GO:0006817 4 0.022
regulation of cell projection organization GO:0031344 92 0.022
nephron morphogenesis GO:0072028 3 0.021
establishment of protein localization GO:0045184 163 0.021
circadian behavior GO:0048512 76 0.021
gland development GO:0048732 191 0.021
regulation of notch signaling pathway GO:0008593 100 0.021
embryonic pattern specification GO:0009880 174 0.021
positive regulation of transcription from rna polymerase ii promoter GO:0045944 204 0.021
single organism intracellular transport GO:1902582 207 0.021
neuroblast proliferation GO:0007405 74 0.021
Mouse
synaptic growth at neuromuscular junction GO:0051124 119 0.021
establishment or maintenance of cell polarity GO:0007163 167 0.021
positive regulation of phosphorus metabolic process GO:0010562 139 0.021
purine ribonucleotide catabolic process GO:0009154 109 0.021
positive regulation of epithelial cell differentiation GO:0030858 1 0.020
digestive system development GO:0055123 149 0.020
cognition GO:0050890 141 0.020
positive regulation of cellular amino acid metabolic process GO:0045764 0 0.020
eye photoreceptor cell differentiation GO:0001754 145 0.020
apoptotic process GO:0006915 159 0.020
regulation of jnk cascade GO:0046328 40 0.020
innate immune response GO:0045087 144 0.020
jnk cascade GO:0007254 50 0.020
response to lipopolysaccharide GO:0032496 4 0.020
negative regulation of response to stimulus GO:0048585 258 0.019
Fly
regulation of multicellular organismal development GO:2000026 414 0.019
ribonucleotide metabolic process GO:0009259 145 0.019
regulation of anatomical structure morphogenesis GO:0022603 242 0.019
negative regulation of cell death GO:0060548 81 0.019
regulation of circadian rhythm GO:0042752 49 0.019
nephron development GO:0072006 3 0.019
regulation of epithelial cell differentiation GO:0030856 4 0.019
organophosphate metabolic process GO:0019637 195 0.019
purine nucleotide metabolic process GO:0006163 146 0.019
microtubule organizing center organization GO:0031023 168 0.019
Fly
positive regulation of multicellular organismal process GO:0051240 143 0.018
secretion GO:0046903 109 0.018
defense response to other organism GO:0098542 225 0.018
cuticle development GO:0042335 86 0.018
small gtpase mediated signal transduction GO:0007264 88 0.018
skeletal muscle organ development GO:0060538 48 0.018
establishment of ommatidial planar polarity GO:0042067 49 0.018
nuclear division GO:0000280 332 0.018
Fly
regulation of mitotic cell cycle GO:0007346 190 0.018
response to abiotic stimulus GO:0009628 341 0.018
actin filament organization GO:0007015 126 0.018
cellular macromolecular complex assembly GO:0034622 153 0.018
body morphogenesis GO:0010171 2 0.018
ras protein signal transduction GO:0007265 88 0.018
response to organic substance GO:0010033 284 0.018
head development GO:0060322 135 0.018
sensory organ morphogenesis GO:0090596 260 0.018
positive regulation of cellular component biogenesis GO:0044089 80 0.018
cell death GO:0008219 279 0.018
regulation of small gtpase mediated signal transduction GO:0051056 93 0.018
muscle attachment GO:0016203 36 0.018
regulation of cellular response to stress GO:0080135 89 0.018
establishment of planar polarity GO:0001736 87 0.018
positive regulation of programmed cell death GO:0043068 62 0.017
cellular catabolic process GO:0044248 372 0.017
dendrite development GO:0016358 204 0.017
Fly
response to biotic stimulus GO:0009607 294 0.017
torso signaling pathway GO:0008293 21 0.017
positive regulation of biosynthetic process GO:0009891 316 0.017
regulation of organelle organization GO:0033043 196 0.017
Fly
developmental pigmentation GO:0048066 68 0.017
regulation of stress activated protein kinase signaling cascade GO:0070302 42 0.017
positive regulation of ras gtpase activity GO:0032320 36 0.017
striated muscle cell development GO:0055002 50 0.017
nucleoside phosphate metabolic process GO:0006753 162 0.017
regulation of phosphorylation GO:0042325 147 0.017
memory GO:0007613 94 0.017
imaginal disc derived wing vein specification GO:0007474 48 0.017
cellular amino acid metabolic process GO:0006520 61 0.017
secretion by cell GO:0032940 101 0.017
immune system development GO:0002520 57 0.016
generation of precursor metabolites and energy GO:0006091 42 0.016
phagocytosis GO:0006909 215 0.016
imaginal disc pattern formation GO:0007447 91 0.016
amine metabolic process GO:0009308 12 0.016
negative regulation of cell division GO:0051782 17 0.016
immune response regulating signaling pathway GO:0002764 2 0.016
developmental programmed cell death GO:0010623 138 0.016
stem cell differentiation GO:0048863 117 0.016
organic substance catabolic process GO:1901575 308 0.016
salivary gland morphogenesis GO:0007435 145 0.016
cellular response to mechanical stimulus GO:0071260 2 0.016
cell growth GO:0016049 108 0.016
positive regulation of rna metabolic process GO:0051254 271 0.016
catabolic process GO:0009056 409 0.016
response to bacterium GO:0009617 198 0.016
positive regulation of apoptotic process GO:0043065 47 0.016
cell cycle phase transition GO:0044770 140 0.016
wing disc pattern formation GO:0035222 66 0.016
kidney development GO:0001822 3 0.016
cellular protein localization GO:0034613 160 0.015
Fly
positive regulation of cell differentiation GO:0045597 64 0.015
positive regulation of nitrogen compound metabolic process GO:0051173 354 0.015
purine nucleoside triphosphate metabolic process GO:0009144 119 0.015
oxoacid metabolic process GO:0043436 103 0.015
taxis GO:0042330 304 0.015
cellular amine metabolic process GO:0044106 12 0.015
regulation of immune system process GO:0002682 176 0.015
programmed cell death GO:0012501 257 0.015
morphogenesis of a branching structure GO:0001763 45 0.015
eye antennal disc development GO:0035214 60 0.015
molting cycle chitin based cuticle GO:0007591 56 0.015
protein complex assembly GO:0006461 200 0.015
Fly
circulatory system development GO:0072359 82 0.015
organonitrogen compound metabolic process GO:1901564 318 0.015
regulation of synapse assembly GO:0051963 94 0.014
response to light stimulus GO:0009416 124 0.014
epithelial cell migration GO:0010631 148 0.014
multicellular organismal homeostasis GO:0048871 41 0.014
dna metabolic process GO:0006259 227 0.014
peptidyl amino acid modification GO:0018193 105 0.014
negative regulation of cell cycle phase transition GO:1901988 103 0.014
positive regulation of cellular component organization GO:0051130 156 0.014
regulation of synaptic growth at neuromuscular junction GO:0008582 89 0.014
regulation of immune response GO:0050776 118 0.014
epidermis development GO:0008544 65 0.014
regulation of hydrolase activity GO:0051336 97 0.014
apoptotic process involved in morphogenesis GO:0060561 3 0.014
regulation of cell division GO:0051302 72 0.014
reproductive system development GO:0061458 74 0.014
positive regulation of nucleobase containing compound metabolic process GO:0045935 332 0.014
cellular ketone metabolic process GO:0042180 24 0.014
regulation of cell proliferation GO:0042127 163 0.014
positive regulation of cell motility GO:2000147 3 0.014
urogenital system development GO:0001655 72 0.014
striated muscle cell differentiation GO:0051146 90 0.014
chitin based cuticle development GO:0040003 49 0.014
positive regulation of lipid biosynthetic process GO:0046889 3 0.014
chorion containing eggshell formation GO:0007304 105 0.014
positive regulation of transport GO:0051050 92 0.014
regulation of cell differentiation GO:0045595 302 0.014
ribose phosphate metabolic process GO:0019693 145 0.013
nephron epithelium morphogenesis GO:0072088 3 0.013
proteolysis GO:0006508 192 0.013
cellular macromolecule localization GO:0070727 220 0.013
Fly
anion transport GO:0006820 41 0.013
positive regulation of lipid metabolic process GO:0045834 4 0.013
cellular response to organic substance GO:0071310 132 0.013
positive regulation of intracellular signal transduction GO:1902533 116 0.013
cellular protein modification process GO:0006464 438 0.013
muscle cell development GO:0055001 50 0.013
leg disc development GO:0035218 92 0.013
protein localization to organelle GO:0033365 82 0.013
wound healing GO:0042060 75 0.013
negative regulation of signal transduction GO:0009968 206 0.013
Fly
guanosine containing compound catabolic process GO:1901069 74 0.013
g protein coupled receptor signaling pathway GO:0007186 136 0.013
intracellular protein transport GO:0006886 104 0.013
organelle fission GO:0048285 340 0.013
Fly
salivary gland development GO:0007431 162 0.012
learning GO:0007612 75 0.012
regulation of cell cycle phase transition GO:1901987 130 0.012
negative regulation of cell differentiation GO:0045596 143 0.012
locomotory behavior GO:0007626 176 0.012
glycosyl compound catabolic process GO:1901658 112 0.012
centrosome organization GO:0051297 163 0.012
Fly
positive regulation of catalytic activity GO:0043085 118 0.012
purine containing compound catabolic process GO:0072523 112 0.012
regulation of cellular protein metabolic process GO:0032268 243 0.012
positive regulation of mapk cascade GO:0043410 63 0.012
negative regulation of cellular component organization GO:0051129 108 0.012
macromolecule catabolic process GO:0009057 161 0.012
response to endogenous stimulus GO:0009719 119 0.012
response to copper ion GO:0046688 4 0.012
endodermal cell differentiation GO:0035987 3 0.012
regulation of cellular amino acid metabolic process GO:0006521 0 0.012
cellular response to biotic stimulus GO:0071216 4 0.012
mesenchymal cell differentiation GO:0048762 1 0.012
cellular response to lipopolysaccharide GO:0071222 3 0.012
regulation of cellular amine metabolic process GO:0033238 3 0.012
negative regulation of catalytic activity GO:0043086 42 0.012
regulation of embryonic development GO:0045995 68 0.012
nucleotide metabolic process GO:0009117 161 0.012
positive regulation of protein metabolic process GO:0051247 128 0.012
negative regulation of molecular function GO:0044092 51 0.011
neuromuscular synaptic transmission GO:0007274 67 0.011
negative regulation of mitotic cell cycle phase transition GO:1901991 103 0.011
defense response to bacterium GO:0042742 178 0.011
anatomical structure homeostasis GO:0060249 97 0.011
single organism catabolic process GO:0044712 228 0.011
protein catabolic process GO:0030163 101 0.011
single organism behavior GO:0044708 391 0.011
regulation of neurogenesis GO:0050767 158 0.011
establishment of spindle localization GO:0051293 22 0.011
renal tubule morphogenesis GO:0061333 44 0.011
positive regulation of molecular function GO:0044093 136 0.011
negative regulation of protein metabolic process GO:0051248 85 0.011
regulation of mitotic cell cycle phase transition GO:1901990 130 0.011
glycosyl compound metabolic process GO:1901657 127 0.011
peptidyl threonine modification GO:0018210 3 0.011
imaginal disc derived wing vein morphogenesis GO:0008586 44 0.011
regulation of wnt signaling pathway GO:0030111 68 0.011
Fly
ion transport GO:0006811 145 0.011
cellular response to molecule of bacterial origin GO:0071219 3 0.011
positive regulation of gtpase activity GO:0043547 43 0.011
rna splicing via transesterification reactions GO:0000375 73 0.011
nucleoside catabolic process GO:0009164 112 0.011
gonad development GO:0008406 50 0.011
organic cyclic compound catabolic process GO:1901361 168 0.011
positive regulation of developmental process GO:0051094 143 0.011
anterior posterior axis specification GO:0009948 109 0.011
positive regulation of immune response GO:0050778 63 0.010
larval development GO:0002164 104 0.010
negative regulation of nervous system development GO:0051961 92 0.010
positive regulation of nervous system development GO:0051962 69 0.010
purine ribonucleoside catabolic process GO:0046130 112 0.010
organic hydroxy compound biosynthetic process GO:1901617 21 0.010
epidermal growth factor receptor signaling pathway GO:0007173 58 0.010
purine nucleoside monophosphate metabolic process GO:0009126 50 0.010
negative regulation of developmental process GO:0051093 201 0.010
stem cell division GO:0017145 69 0.010
adherens junction organization GO:0034332 27 0.010
purine ribonucleoside triphosphate metabolic process GO:0009205 119 0.010
mitotic cytokinesis GO:0000281 50 0.010
Fly
morphogenesis of follicular epithelium GO:0016333 36 0.010
regulation of neuron differentiation GO:0045664 103 0.010
heterocycle catabolic process GO:0046700 166 0.010
notch signaling pathway GO:0007219 120 0.010
hormone biosynthetic process GO:0042446 20 0.010
macromolecular complex assembly GO:0065003 256 0.010
Fly
regulation of developmental growth GO:0048638 174 0.010
regulation of cellular component biogenesis GO:0044087 201 0.010

RacGAP84C disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in fly and predicted with the fly functional network.

Disease DO term ID Size Probability Func Analog Org
disease of anatomical entity DOID:7 0 0.024
cancer DOID:162 0 0.010
disease of cellular proliferation DOID:14566 0 0.010
organ system cancer DOID:0050686 0 0.010