Drosophila melanogaster

217 known processes

dco (Dmel_CG2048)

discs overgrown

(Aliases: l(3)discs overgrown-1,l(3)dco-1,0915/10,l(3)dco,l(3)discs overgrown,Dmel\CG2048,CKIepsilon,DCO,l(3)rK215,0538/13,CK1epsilon,DBT/CK1epsilon,DCO/CKIe,1396/02,dco-1,Dco/CK1,dCKIepsilon,l(3)S144701,Dco,1460/09,dbt,1447/01,l(3)S053813,ddbt,ck1epsilon,CG2048,DBT,l(3)j3B9,Dbt)

dco biological process predictions


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Biological process GO term ID Process size Probability Func Analog Org
circadian rhythm GO:0007623 105 0.999
negative regulation of gene expression GO:0010629 387 0.994
imaginal disc derived appendage morphogenesis GO:0035114 395 0.989
positive regulation of macromolecule metabolic process GO:0010604 405 0.988
regionalization GO:0003002 416 0.988
negative regulation of cellular biosynthetic process GO:0031327 277 0.986
locomotory behavior GO:0007626 176 0.985
epithelial cell differentiation GO:0030855 322 0.982
negative regulation of transcription from rna polymerase ii promoter GO:0000122 119 0.980
post embryonic appendage morphogenesis GO:0035120 385 0.977
negative regulation of transcription dna templated GO:0045892 237 0.975
regulation of transcription from rna polymerase ii promoter GO:0006357 378 0.973
negative regulation of macromolecule biosynthetic process GO:0010558 270 0.966
cellular protein modification process GO:0006464 438 0.965
negative regulation of rna biosynthetic process GO:1902679 240 0.962
rhythmic process GO:0048511 106 0.950
negative regulation of nucleic acid templated transcription GO:1903507 240 0.950
negative regulation of nitrogen compound metabolic process GO:0051172 265 0.948
negative regulation of nucleobase containing compound metabolic process GO:0045934 261 0.948
immune system process GO:0002376 347 0.944
negative regulation of cellular metabolic process GO:0031324 382 0.941
positive regulation of transcription from rna polymerase ii promoter GO:0045944 204 0.940
negative regulation of cellular macromolecule biosynthetic process GO:2000113 267 0.939
positive regulation of gene expression GO:0010628 290 0.930
negative regulation of rna metabolic process GO:0051253 251 0.927
appendage development GO:0048736 401 0.922
circadian behavior GO:0048512 76 0.918
positive regulation of nucleobase containing compound metabolic process GO:0045935 332 0.916
catabolic process GO:0009056 409 0.915
negative regulation of response to stimulus GO:0048585 258 0.909
Mouse Fly
transcription from rna polymerase ii promoter GO:0006366 368 0.897
regulation of response to stress GO:0080134 200 0.894
protein acetylation GO:0006473 39 0.889
regulation of immune system process GO:0002682 176 0.879
regulation of anatomical structure morphogenesis GO:0022603 242 0.851
compound eye photoreceptor cell differentiation GO:0001751 140 0.846
defense response GO:0006952 300 0.837
positive regulation of transcription dna templated GO:0045893 266 0.830
imaginal disc derived appendage development GO:0048737 399 0.826
positive regulation of rna metabolic process GO:0051254 271 0.813
negative regulation of signal transduction GO:0009968 206 0.813
Mouse Fly
regulation of localization GO:0032879 275 0.795
enteroendocrine cell differentiation GO:0035883 1 0.764
positive regulation of nitrogen compound metabolic process GO:0051173 354 0.762
negative regulation of cell communication GO:0010648 223 0.758
Mouse Fly
photoreceptor cell differentiation GO:0046530 170 0.752
regulation of intracellular signal transduction GO:1902531 236 0.748
cellular catabolic process GO:0044248 372 0.746
establishment of protein localization GO:0045184 163 0.738
positive regulation of phosphate metabolic process GO:0045937 139 0.732
Human
positive regulation of macromolecule biosynthetic process GO:0010557 283 0.729
regulation of growth GO:0040008 233 0.725
negative regulation of biosynthetic process GO:0009890 277 0.722
developmental growth GO:0048589 280 0.713
protein modification process GO:0036211 438 0.709
eye photoreceptor cell differentiation GO:0001754 145 0.705
tube development GO:0035295 244 0.699
cellular protein catabolic process GO:0044257 83 0.695
response to oxidative stress GO:0006979 86 0.695
positive regulation of rna biosynthetic process GO:1902680 266 0.688
organic substance catabolic process GO:1901575 308 0.682
positive regulation of nucleic acid templated transcription GO:1903508 266 0.659
eye development GO:0001654 323 0.659
muscle structure development GO:0061061 224 0.651
cell migration GO:0016477 238 0.645
cell proliferation GO:0008283 299 0.644
regulation of organ morphogenesis GO:2000027 78 0.643
neurological system process GO:0050877 358 0.635
tissue morphogenesis GO:0048729 297 0.626
biological adhesion GO:0022610 138 0.619
compound eye development GO:0048749 307 0.615
appendage morphogenesis GO:0035107 397 0.608
aging GO:0007568 143 0.608
proteasome mediated ubiquitin dependent protein catabolic process GO:0043161 54 0.601
protein localization to nucleus GO:0034504 55 0.591
regulation of multicellular organismal development GO:2000026 414 0.589
protein localization GO:0008104 284 0.562
Yeast Mouse
modification dependent macromolecule catabolic process GO:0043632 79 0.555
intracellular signal transduction GO:0035556 300 0.544
proteolysis involved in cellular protein catabolic process GO:0051603 83 0.539
regulation of cellular response to stress GO:0080135 89 0.539
imaginal disc derived wing morphogenesis GO:0007476 337 0.534
regulation of muscle organ development GO:0048634 13 0.530
internal protein amino acid acetylation GO:0006475 38 0.524
regulation of molecular function GO:0065009 217 0.522
compound eye morphogenesis GO:0001745 249 0.517
regulation of photoreceptor cell differentiation GO:0046532 34 0.513
multi organism reproductive behavior GO:0044705 121 0.507
modification dependent protein catabolic process GO:0019941 78 0.504
cell motility GO:0048870 251 0.504
multicellular organismal reproductive behavior GO:0033057 110 0.504
ubiquitin dependent protein catabolic process GO:0006511 78 0.499
positive regulation of cellular biosynthetic process GO:0031328 316 0.492
regulation of organ growth GO:0046620 42 0.484
dendrite development GO:0016358 204 0.482
phosphorylation GO:0016310 294 0.472
response to nutrient levels GO:0031667 114 0.469
regulation of cellular protein metabolic process GO:0032268 243 0.461
small molecule metabolic process GO:0044281 305 0.459
regulation of response to external stimulus GO:0032101 115 0.458
organelle assembly GO:0070925 198 0.457
Human
regulation of protein modification process GO:0031399 112 0.452
Human
multi organism behavior GO:0051705 175 0.448
Fly
negative regulation of intracellular signal transduction GO:1902532 57 0.447
multicellular organismal aging GO:0010259 140 0.447
regulation of cellular localization GO:0060341 136 0.435
rhythmic behavior GO:0007622 76 0.434
morphogenesis of an epithelium GO:0002009 276 0.433
regulation of developmental growth GO:0048638 174 0.429
Worm
positive regulation of signal transduction GO:0009967 223 0.428
Human Mouse
determination of adult lifespan GO:0008340 137 0.428
regulation of cell cycle phase transition GO:1901987 130 0.426
regulation of catabolic process GO:0009894 170 0.425
chromosome organization GO:0051276 360 0.424
regulation of phosphorus metabolic process GO:0051174 210 0.420
Human
regulation of phosphate metabolic process GO:0019220 210 0.407
Human
macromolecule catabolic process GO:0009057 161 0.398
cardiovascular system development GO:0072358 82 0.394
response to organic substance GO:0010033 284 0.393
circadian regulation of gene expression GO:0032922 5 0.389
Mouse
organophosphate metabolic process GO:0019637 195 0.385
mrna metabolic process GO:0016071 124 0.373
segmentation GO:0035282 207 0.372
regulation of defense response GO:0031347 102 0.366
reproductive behavior GO:0019098 122 0.364
positive regulation of growth GO:0045927 75 0.356
regulation of immune response GO:0050776 118 0.355
internal peptidyl lysine acetylation GO:0018393 38 0.353
localization of cell GO:0051674 257 0.345
positive regulation of cell communication GO:0010647 250 0.344
Human Mouse
columnar cuboidal epithelial cell differentiation GO:0002065 256 0.342
dendrite morphogenesis GO:0048813 199 0.340
regulation of neurogenesis GO:0050767 158 0.334
adult behavior GO:0030534 137 0.334
embryonic pattern specification GO:0009880 174 0.334
regulation of cell proliferation GO:0042127 163 0.333
cell adhesion GO:0007155 136 0.331
eye photoreceptor cell fate commitment GO:0042706 37 0.322
cell division GO:0051301 248 0.319
peptidyl lysine acetylation GO:0018394 39 0.317
compound eye photoreceptor fate commitment GO:0001752 36 0.314
regulation of cellular catabolic process GO:0031329 157 0.312
regulation of transport GO:0051049 181 0.306
imaginal disc derived wing vein morphogenesis GO:0008586 44 0.301
positive regulation of signaling GO:0023056 243 0.299
Human Mouse
negative regulation of multicellular organismal process GO:0051241 142 0.298
tor signaling GO:0031929 32 0.298
cell fate specification GO:0001708 71 0.296
positive regulation of phosphorus metabolic process GO:0010562 139 0.291
Human
innate immune response GO:0045087 144 0.288
cellular response to radiation GO:0071478 52 0.285
regulation of apoptotic signaling pathway GO:2001233 10 0.283
establishment of localization in cell GO:0051649 402 0.280
immune system development GO:0002520 57 0.278
cellular response to endogenous stimulus GO:0071495 80 0.277
growth GO:0040007 359 0.276
pole plasm assembly GO:0007315 61 0.272
nucleotide metabolic process GO:0009117 161 0.271
dna metabolic process GO:0006259 227 0.270
Yeast Fly
regulation of pathway restricted smad protein phosphorylation GO:0060393 1 0.269
organonitrogen compound metabolic process GO:1901564 318 0.267
negative regulation of signaling GO:0023057 219 0.257
Mouse Fly
oocyte differentiation GO:0009994 145 0.251
carbohydrate derivative metabolic process GO:1901135 217 0.251
regulation of cell death GO:0010941 173 0.250
response to extracellular stimulus GO:0009991 116 0.246
multicellular organismal homeostasis GO:0048871 41 0.245
mitotic cell cycle phase transition GO:0044772 138 0.243
protein localization to organelle GO:0033365 82 0.242
response to organic cyclic compound GO:0014070 89 0.236
multicellular organism growth GO:0035264 46 0.236
Worm
head development GO:0060322 135 0.234
mrna processing GO:0006397 104 0.231
body morphogenesis GO:0010171 2 0.230
Worm
lipid metabolic process GO:0006629 121 0.229
mapk cascade GO:0000165 107 0.225
single organism behavior GO:0044708 391 0.223
wing disc morphogenesis GO:0007472 344 0.223
regulation of protein metabolic process GO:0051246 256 0.222
central nervous system development GO:0007417 201 0.218
protein targeting to nucleus GO:0044744 51 0.218
carbohydrate derivative biosynthetic process GO:1901137 85 0.215
regulation of circadian rhythm GO:0042752 49 0.213
muscle organ development GO:0007517 127 0.212
homeostatic process GO:0042592 199 0.211
regulation of neuron differentiation GO:0045664 103 0.210
blastoderm segmentation GO:0007350 159 0.206
cell death GO:0008219 279 0.206
regulation of system process GO:0044057 36 0.206
histone modification GO:0016570 106 0.205
positive regulation of biosynthetic process GO:0009891 316 0.204
response to starvation GO:0042594 97 0.203
regulation of secretion by cell GO:1903530 39 0.202
positive regulation of response to stimulus GO:0048584 323 0.201
Human Mouse
response to endogenous stimulus GO:0009719 119 0.200
covalent chromatin modification GO:0016569 106 0.199
regulation of imaginal disc growth GO:0045570 26 0.198
cellular response to abiotic stimulus GO:0071214 58 0.198
protein import GO:0017038 55 0.197
protein catabolic process GO:0030163 101 0.193
connective tissue development GO:0061448 3 0.192
negative regulation of growth GO:0045926 84 0.191
negative regulation of defense response GO:0031348 35 0.190
response to bacterium GO:0009617 198 0.190
protein phosphorylation GO:0006468 169 0.189
columnar cuboidal epithelial cell development GO:0002066 249 0.189
autophagy GO:0006914 108 0.184
negative regulation of cell death GO:0060548 81 0.183
signal release GO:0023061 49 0.183
signal transduction by phosphorylation GO:0023014 107 0.182
regulation of cell differentiation GO:0045595 302 0.182
regulation of mrna metabolic process GO:1903311 72 0.177
imaginal disc derived leg morphogenesis GO:0007480 80 0.177
protein import into nucleus GO:0006606 51 0.176
actin cytoskeleton organization GO:0030036 206 0.174
protein transport GO:0015031 155 0.171
ras protein signal transduction GO:0007265 88 0.166
single organism cell adhesion GO:0098602 47 0.166
chromatin modification GO:0016568 147 0.165
histone h4 acetylation GO:0043967 13 0.164
reproductive structure development GO:0048608 74 0.164
response to insulin GO:0032868 29 0.163
regulation of cell fate commitment GO:0010453 29 0.161
immune response GO:0006955 246 0.161
purine ribonucleotide catabolic process GO:0009154 109 0.160
negative regulation of cell proliferation GO:0008285 69 0.158
establishment of protein localization to organelle GO:0072594 62 0.157
organonitrogen compound catabolic process GO:1901565 128 0.156
histone acetylation GO:0016573 38 0.155
cellular response to hormone stimulus GO:0032870 44 0.151
ribonucleoside metabolic process GO:0009119 127 0.151
cellular response to organic substance GO:0071310 132 0.149
proteasomal protein catabolic process GO:0010498 59 0.149
epithelial cell development GO:0002064 274 0.143
aromatic compound catabolic process GO:0019439 166 0.142
muscle cell development GO:0055001 50 0.141
positive regulation of canonical wnt signaling pathway GO:0090263 7 0.140
Human Mouse
adult locomotory behavior GO:0008344 76 0.138
regulation of striated muscle tissue development GO:0016202 5 0.137
rna splicing via transesterification reactions with bulged adenosine as nucleophile GO:0000377 73 0.137
negative regulation of molecular function GO:0044092 51 0.136
pole plasm mrna localization GO:0019094 49 0.135
protein acylation GO:0043543 42 0.134
circulatory system development GO:0072359 82 0.134
nucleoside metabolic process GO:0009116 127 0.133
regulation of protein transport GO:0051223 57 0.133
notch signaling pathway GO:0007219 120 0.128
response to other organism GO:0051707 293 0.127
cellular response to insulin stimulus GO:0032869 28 0.127
nuclear transport GO:0051169 72 0.126
cellular response to dna damage stimulus GO:0006974 223 0.124
Yeast Fly
regulation of nucleocytoplasmic transport GO:0046822 35 0.123
positive regulation of intracellular signal transduction GO:1902533 116 0.121
salivary gland morphogenesis GO:0007435 145 0.120
cell cycle phase transition GO:0044770 140 0.118
response to radiation GO:0009314 155 0.117
muscle tissue development GO:0060537 30 0.116
negative regulation of developmental growth GO:0048640 64 0.116
actin filament based process GO:0030029 220 0.116
imaginal disc growth GO:0007446 37 0.116
gland development GO:0048732 191 0.116
cellular response to chemical stimulus GO:0070887 199 0.112
anterior posterior axis specification embryo GO:0008595 103 0.111
response to abiotic stimulus GO:0009628 341 0.111
nuclear import GO:0051170 51 0.109
positive regulation of phosphorylation GO:0042327 87 0.107
Human
secretion by cell GO:0032940 101 0.105
oocyte axis specification GO:0007309 108 0.105
regulation of behavior GO:0050795 75 0.104
muscle cell differentiation GO:0042692 103 0.104
enzyme linked receptor protein signaling pathway GO:0007167 179 0.104
positive regulation of developmental growth GO:0048639 62 0.103
Worm
response to wounding GO:0009611 94 0.103
positive regulation of erk1 and erk2 cascade GO:0070374 36 0.101
response to biotic stimulus GO:0009607 294 0.101
defense response to gram negative bacterium GO:0050829 94 0.100
regulation of mitotic cell cycle GO:0007346 190 0.099
nucleobase containing compound catabolic process GO:0034655 165 0.099
carbohydrate metabolic process GO:0005975 82 0.098
brain development GO:0007420 120 0.098
regulation of protein phosphorylation GO:0001932 64 0.098
Human
spermatogenesis GO:0007283 200 0.098
myotube cell development GO:0014904 3 0.096
immune response regulating signaling pathway GO:0002764 2 0.096
oocyte development GO:0048599 124 0.096
programmed cell death GO:0012501 257 0.096
epithelial tube morphogenesis GO:0060562 88 0.096
organic cyclic compound catabolic process GO:1901361 168 0.095
single organism carbohydrate metabolic process GO:0044723 72 0.095
response to organonitrogen compound GO:0010243 75 0.094
anterior posterior axis specification GO:0009948 109 0.093
organelle fission GO:0048285 340 0.092
Yeast
single organism catabolic process GO:0044712 228 0.092
jnk cascade GO:0007254 50 0.092
cellular response to oxygen containing compound GO:1901701 79 0.092
cell aging GO:0007569 2 0.092
guanosine containing compound catabolic process GO:1901069 74 0.091
positive regulation of pathway restricted smad protein phosphorylation GO:0010862 1 0.090
cytoplasmic transport GO:0016482 130 0.090
Yeast
stem cell division GO:0017145 69 0.090
secretion GO:0046903 109 0.089
positive regulation of mitotic cell cycle GO:0045931 34 0.088
positive regulation of protein metabolic process GO:0051247 128 0.088
cellular response to oxidative stress GO:0034599 28 0.087
sister chromatid segregation GO:0000819 92 0.087
tissue homeostasis GO:0001894 36 0.086
negative regulation of immune system process GO:0002683 50 0.085
guanosine containing compound metabolic process GO:1901068 74 0.085
single organism nuclear import GO:1902593 51 0.084
lateral inhibition GO:0046331 206 0.083
olfactory behavior GO:0042048 97 0.083
dephosphorylation GO:0016311 51 0.082
intracellular transport GO:0046907 228 0.082
Yeast
ribose phosphate metabolic process GO:0019693 145 0.081
locomotor rhythm GO:0045475 56 0.081
regulation of mrna processing GO:0050684 71 0.079
response to oxygen containing compound GO:1901700 200 0.079
positive regulation of mapk cascade GO:0043410 63 0.079
axonogenesis GO:0007409 290 0.079
positive regulation of cell proliferation GO:0008284 47 0.078
negative regulation of cell cycle GO:0045786 116 0.078
purine nucleoside catabolic process GO:0006152 112 0.077
rna splicing via transesterification reactions GO:0000375 73 0.077
purine ribonucleotide metabolic process GO:0009150 145 0.076
compound eye photoreceptor development GO:0042051 78 0.076
olfactory learning GO:0008355 56 0.076
cellular macromolecule catabolic process GO:0044265 136 0.076
rna splicing GO:0008380 83 0.076
peptidyl lysine modification GO:0018205 57 0.075
imaginal disc derived wing vein specification GO:0007474 48 0.075
digestive system development GO:0055123 149 0.074
axon development GO:0061564 297 0.074
negative regulation of apoptotic process GO:0043066 63 0.074
embryonic development via the syncytial blastoderm GO:0001700 148 0.074
regulation of r7 cell differentiation GO:0045676 15 0.073
purine ribonucleoside triphosphate metabolic process GO:0009205 119 0.073
regulation of jnk cascade GO:0046328 40 0.073
ribonucleotide metabolic process GO:0009259 145 0.072
positive regulation of proteasomal ubiquitin dependent protein catabolic process GO:0032436 19 0.072
protein dephosphorylation GO:0006470 27 0.072
camera type eye development GO:0043010 4 0.071
nucleoside catabolic process GO:0009164 112 0.071
negative regulation of programmed cell death GO:0043069 72 0.070
tripartite regional subdivision GO:0007351 103 0.070
regulation of cellular response to insulin stimulus GO:1900076 17 0.069
embryonic morphogenesis GO:0048598 206 0.069
striated muscle cell differentiation GO:0051146 90 0.069
regulation of cytoplasmic transport GO:1903649 47 0.068
regulation of cell cycle GO:0051726 291 0.067
regulation of stress activated mapk cascade GO:0032872 41 0.067
regulation of innate immune response GO:0045088 71 0.067
stress activated protein kinase signaling cascade GO:0031098 55 0.067
photoreceptor cell fate commitment GO:0046552 41 0.066
protein complex assembly GO:0006461 200 0.066
Human
sex differentiation GO:0007548 81 0.065
positive regulation of multicellular organismal process GO:0051240 143 0.064
Worm
positive regulation of cellular protein metabolic process GO:0032270 118 0.064
positive regulation of nucleocytoplasmic transport GO:0046824 24 0.063
stress activated mapk cascade GO:0051403 52 0.063
anatomical structure homeostasis GO:0060249 97 0.063
tube morphogenesis GO:0035239 191 0.063
cellular lipid metabolic process GO:0044255 83 0.062
positive regulation of apoptotic process GO:0043065 47 0.061
striated muscle cell development GO:0055002 50 0.060
defense response to other organism GO:0098542 225 0.060
anterior posterior pattern specification GO:0009952 136 0.059
skeletal muscle organ development GO:0060538 48 0.059
purine nucleoside triphosphate catabolic process GO:0009146 108 0.059
negative regulation of cell development GO:0010721 62 0.059
cellular nitrogen compound catabolic process GO:0044270 165 0.058
somatic stem cell division GO:0048103 37 0.058
regulation of imaginal disc derived wing size GO:0044719 20 0.058
apoptotic signaling pathway GO:0097190 27 0.058
regulation of anatomical structure size GO:0090066 163 0.058
oocyte construction GO:0007308 112 0.057
negative regulation of cell differentiation GO:0045596 143 0.057
carbohydrate derivative catabolic process GO:1901136 118 0.056
small gtpase mediated signal transduction GO:0007264 88 0.056
intracellular protein transport GO:0006886 104 0.056
cellular protein localization GO:0034613 160 0.056
Yeast Mouse
cellular response to lipid GO:0071396 20 0.055
negative regulation of catalytic activity GO:0043086 42 0.055
striated muscle tissue development GO:0014706 27 0.054
nucleoside triphosphate metabolic process GO:0009141 120 0.054
response to transforming growth factor beta GO:0071559 18 0.054
cellular metal ion homeostasis GO:0006875 31 0.053
cellular response to organonitrogen compound GO:0071417 36 0.053
nucleoside triphosphate catabolic process GO:0009143 108 0.053
nucleoside phosphate metabolic process GO:0006753 162 0.053
regulation of protein catabolic process GO:0042176 55 0.053
nucleobase containing small molecule metabolic process GO:0055086 174 0.053
oviposition GO:0018991 19 0.053
glycosyl compound metabolic process GO:1901657 127 0.053
regulation of transferase activity GO:0051338 58 0.052
protein targeting GO:0006605 64 0.052
cell type specific apoptotic process GO:0097285 38 0.052
metal ion transport GO:0030001 74 0.052
regulation of stress activated protein kinase signaling cascade GO:0070302 42 0.052
metal ion homeostasis GO:0055065 44 0.052
phagocytosis GO:0006909 215 0.051
Fly
regulation of actin filament based process GO:0032970 42 0.051
regulation of notch signaling pathway GO:0008593 100 0.051
positive regulation of cell differentiation GO:0045597 64 0.051
purine nucleoside metabolic process GO:0042278 127 0.050
apoptotic process GO:0006915 159 0.050
cellular homeostasis GO:0019725 80 0.050
hematopoietic or lymphoid organ development GO:0048534 57 0.049
photoreceptor cell development GO:0042461 96 0.049
mrna splicing via spliceosome GO:0000398 73 0.049
regulation of phosphorylation GO:0042325 147 0.049
Human
carboxylic acid metabolic process GO:0019752 92 0.048
meiosis i GO:0007127 59 0.048
Yeast
chromatin organization GO:0006325 207 0.048
regulation of small gtpase mediated signal transduction GO:0051056 93 0.047
somatic muscle development GO:0007525 66 0.047
regulation of proteasomal ubiquitin dependent protein catabolic process GO:0032434 37 0.047
cell fate determination GO:0001709 91 0.047
ion transport GO:0006811 145 0.047
terminal region determination GO:0007362 25 0.047
epidermal cell differentiation GO:0009913 51 0.046
myofibril assembly GO:0030239 36 0.046
inter male aggressive behavior GO:0002121 60 0.046
Fly
male gamete generation GO:0048232 201 0.046
cell cell signaling involved in cell fate commitment GO:0045168 210 0.046
regulation of catalytic activity GO:0050790 185 0.045
muscle fiber development GO:0048747 12 0.045
cell maturation GO:0048469 144 0.045
negative regulation of apoptotic signaling pathway GO:2001234 5 0.045
blood circulation GO:0008015 26 0.045
cellular macromolecule localization GO:0070727 220 0.045
Yeast Mouse
eye morphogenesis GO:0048592 260 0.044
immune response activating signal transduction GO:0002757 2 0.043
regulation of cell development GO:0060284 215 0.042
r7 cell differentiation GO:0045466 43 0.042
ribonucleoside triphosphate metabolic process GO:0009199 119 0.042
regulation of mapk cascade GO:0043408 92 0.042
negative regulation of protein metabolic process GO:0051248 85 0.042
actomyosin structure organization GO:0031032 56 0.042
glycosyl compound catabolic process GO:1901658 112 0.042
heterocycle catabolic process GO:0046700 166 0.041
organonitrogen compound biosynthetic process GO:1901566 117 0.041
organ growth GO:0035265 56 0.041
axon guidance GO:0007411 233 0.041
positive regulation of intracellular protein transport GO:0090316 30 0.041
mesenchymal cell development GO:0014031 1 0.041
regulation of cellular ketone metabolic process GO:0010565 3 0.040
regulation of tor signaling GO:0032006 21 0.040
mitotic nuclear division GO:0007067 213 0.040
Yeast
regulation of programmed cell death GO:0043067 152 0.039
defense response to bacterium GO:0042742 178 0.039
regulation of cell morphogenesis GO:0022604 163 0.039
macromolecule deacylation GO:0098732 11 0.039
cell fate commitment involved in pattern specification GO:0060581 31 0.038
detection of stimulus GO:0051606 156 0.038
peptide metabolic process GO:0006518 80 0.037
gtp catabolic process GO:0006184 72 0.036
positive regulation of cellular catabolic process GO:0031331 95 0.036
glycoprotein metabolic process GO:0009100 41 0.035
negative regulation of phosphorylation GO:0042326 35 0.035
gland morphogenesis GO:0022612 145 0.035
digestive tract development GO:0048565 149 0.035
pole plasm rna localization GO:0007316 52 0.035
actin filament organization GO:0007015 126 0.035
cellular response to peptide hormone stimulus GO:0071375 28 0.035
negative regulation of imaginal disc growth GO:0045571 8 0.035
morphogenesis of a branching epithelium GO:0061138 45 0.034
response to external biotic stimulus GO:0043207 293 0.033
sarcomere organization GO:0045214 26 0.033
positive regulation of transport GO:0051050 92 0.033
purine containing compound catabolic process GO:0072523 112 0.033
imaginal disc derived leg segmentation GO:0036011 26 0.033
heart development GO:0007507 82 0.033
positive regulation of catabolic process GO:0009896 105 0.033
cell activation GO:0001775 9 0.033
negative regulation of phosphate metabolic process GO:0045936 45 0.033
response to hormone GO:0009725 45 0.033
ribonucleoside catabolic process GO:0042454 112 0.032
regulation of protein kinase activity GO:0045859 51 0.032
macromolecular complex assembly GO:0065003 256 0.032
Human
negative regulation of developmental process GO:0051093 201 0.032
regulation of proteolysis involved in cellular protein catabolic process GO:1903050 44 0.031
regulation of multicellular organism growth GO:0040014 40 0.031
Worm
regulation of protein localization to nucleus GO:1900180 29 0.031
rna processing GO:0006396 147 0.031
Yeast
regulation of epithelial cell differentiation GO:0030856 4 0.031
peptidyl amino acid modification GO:0018193 105 0.031
positive regulation of molecular function GO:0044093 136 0.030
morphogenesis of follicular epithelium GO:0016333 36 0.030
response to light stimulus GO:0009416 124 0.030
branching morphogenesis of an epithelial tube GO:0048754 45 0.030
eye antennal disc development GO:0035214 60 0.030
reproductive system development GO:0061458 74 0.030
purine containing compound metabolic process GO:0072521 155 0.030
regulation of ras protein signal transduction GO:0046578 93 0.030
histone deacetylation GO:0016575 9 0.030
sensory organ morphogenesis GO:0090596 260 0.029
regulation of cell substrate adhesion GO:0010810 2 0.029
organic acid metabolic process GO:0006082 103 0.029

dco disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in fly and predicted with the fly functional network.

Disease DO term ID Size Probability Func Analog Org
disease of anatomical entity DOID:7 0 0.081