Drosophila melanogaster

73 known processes

Pkn (Dmel_CG2049)

Protein kinase related to protein kinase N

(Aliases: CG2055,Pk?3,dPKN,Pk45C,PKN,CG2049,v(2)rG232,CT6660,l(2)06736,3-2,PRK2,CT6637,DPKN,Dmel\CG2049,Dpkn,l(2)45Ca)

Pkn biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
post embryonic appendage morphogenesis GO:0035120 385 0.979
tissue morphogenesis GO:0048729 297 0.971
imaginal disc derived wing hair organization GO:0035317 45 0.967
imaginal disc derived appendage morphogenesis GO:0035114 395 0.962
appendage morphogenesis GO:0035107 397 0.962
embryonic development via the syncytial blastoderm GO:0001700 148 0.954
embryonic morphogenesis GO:0048598 206 0.954
establishment of planar polarity GO:0001736 87 0.929
imaginal disc derived appendage development GO:0048737 399 0.918
establishment of tissue polarity GO:0007164 87 0.907
tube development GO:0035295 244 0.886
appendage development GO:0048736 401 0.874
imaginal disc derived wing morphogenesis GO:0007476 337 0.867
morphogenesis of an epithelium GO:0002009 276 0.847
stress activated protein kinase signaling cascade GO:0031098 55 0.846
regulation of establishment of planar polarity GO:0090175 22 0.838
regulation of gtpase activity GO:0043087 44 0.826
rho protein signal transduction GO:0007266 14 0.821
regulation of protein metabolic process GO:0051246 256 0.809
Mouse
ribonucleoside triphosphate metabolic process GO:0009199 119 0.805
tube morphogenesis GO:0035239 191 0.803
gtp catabolic process GO:0006184 72 0.780
regulation of molecular function GO:0065009 217 0.776
Mouse
morphogenesis of a polarized epithelium GO:0001738 93 0.771
digestive tract development GO:0048565 149 0.768
positive regulation of phosphate metabolic process GO:0045937 139 0.761
ion transmembrane transport GO:0034220 122 0.758
regulation of cellular catabolic process GO:0031329 157 0.753
dorsal closure GO:0007391 79 0.740
neuron recognition GO:0008038 101 0.721
regulation of phosphate metabolic process GO:0019220 210 0.701
Mouse
jnk cascade GO:0007254 50 0.689
nucleoside metabolic process GO:0009116 127 0.689
cell motility GO:0048870 251 0.665
Human
regulation of organ morphogenesis GO:2000027 78 0.660
morphogenesis of embryonic epithelium GO:0016331 94 0.659
cellular protein modification process GO:0006464 438 0.658
positive regulation of gtpase activity GO:0043547 43 0.655
biological adhesion GO:0022610 138 0.651
purine nucleoside metabolic process GO:0042278 127 0.644
regulation of cellular protein metabolic process GO:0032268 243 0.641
Mouse
gtp metabolic process GO:0046039 72 0.640
regulation of catabolic process GO:0009894 170 0.625
immune effector process GO:0002252 98 0.622
Mouse
regulation of rho protein signal transduction GO:0035023 20 0.620
guanosine containing compound metabolic process GO:1901068 74 0.614
negative regulation of cell communication GO:0010648 223 0.606
cellular catabolic process GO:0044248 372 0.595
secretion GO:0046903 109 0.591
positive regulation of cellular component organization GO:0051130 156 0.587
glycosyl compound metabolic process GO:1901657 127 0.586
positive regulation of jun kinase activity GO:0043507 4 0.583
positive regulation of rho gtpase activity GO:0032321 19 0.574
regulation of response to stress GO:0080134 200 0.568
imaginal disc derived wing vein morphogenesis GO:0008586 44 0.564
wing disc morphogenesis GO:0007472 344 0.556
spermatid differentiation GO:0048515 114 0.553
regulation of synapse structure and activity GO:0050803 128 0.550
regulation of multicellular organismal development GO:2000026 414 0.543
response to osmotic stress GO:0006970 14 0.542
Mouse
nucleoside triphosphate metabolic process GO:0009141 120 0.541
neurological system process GO:0050877 358 0.532
ribonucleotide catabolic process GO:0009261 109 0.532
hair cell differentiation GO:0035315 47 0.531
regulation of nucleoside metabolic process GO:0009118 50 0.525
regulation of stress activated mapk cascade GO:0032872 41 0.522
establishment of localization in cell GO:0051649 402 0.518
regulation of protein modification process GO:0031399 112 0.513
Mouse
endocytosis GO:0006897 310 0.511
cell migration GO:0016477 238 0.500
Human
positive regulation of cellular protein metabolic process GO:0032270 118 0.494
positive regulation of nucleotide catabolic process GO:0030813 46 0.487
ribonucleoside catabolic process GO:0042454 112 0.485
positive regulation of response to stimulus GO:0048584 323 0.474
positive regulation of nucleotide metabolic process GO:0045981 55 0.473
stress activated mapk cascade GO:0051403 52 0.470
digestive system development GO:0055123 149 0.458
epithelial cell differentiation GO:0030855 322 0.455
positive regulation of cellular catabolic process GO:0031331 95 0.453
compound eye development GO:0048749 307 0.453
regulation of gtp catabolic process GO:0033124 44 0.452
regulation of protein phosphorylation GO:0001932 64 0.447
Mouse
actin filament based process GO:0030029 220 0.431
positive regulation of protein metabolic process GO:0051247 128 0.427
regulation of response to external stimulus GO:0032101 115 0.425
epidermis development GO:0008544 65 0.425
positive regulation of catalytic activity GO:0043085 118 0.420
purine ribonucleoside catabolic process GO:0046130 112 0.420
cell division GO:0051301 248 0.417
Human
positive regulation of phosphorus metabolic process GO:0010562 139 0.414
regulation of stress activated protein kinase signaling cascade GO:0070302 42 0.410
spermatid development GO:0007286 98 0.408
regulation of phosphorus metabolic process GO:0051174 210 0.405
Mouse
catabolic process GO:0009056 409 0.396
purine nucleotide catabolic process GO:0006195 109 0.391
regulation of localization GO:0032879 275 0.389
Human
establishment or maintenance of cell polarity GO:0007163 167 0.387
embryo development ending in birth or egg hatching GO:0009792 152 0.387
regulation of rho gtpase activity GO:0032319 20 0.379
purine ribonucleotide metabolic process GO:0009150 145 0.366
nucleoside catabolic process GO:0009164 112 0.364
positive regulation of purine nucleotide catabolic process GO:0033123 46 0.363
regulation of purine nucleotide catabolic process GO:0033121 48 0.361
regulation of catalytic activity GO:0050790 185 0.360
Mouse
cell junction organization GO:0034330 57 0.355
Human Mouse
regulation of protein kinase activity GO:0045859 51 0.352
Mouse
regulation of jnk cascade GO:0046328 40 0.350
phosphorylation GO:0016310 294 0.348
single organism catabolic process GO:0044712 228 0.347
cellularization GO:0007349 90 0.346
non sensory hair organization GO:0035316 47 0.343
purine nucleoside triphosphate metabolic process GO:0009144 119 0.339
sevenless signaling pathway GO:0045500 4 0.338
cell adhesion GO:0007155 136 0.334
negative regulation of response to stimulus GO:0048585 258 0.330
chemotaxis GO:0006935 249 0.329
purine ribonucleoside metabolic process GO:0046128 127 0.328
regulation of transmembrane transport GO:0034762 27 0.324
nucleoside triphosphate catabolic process GO:0009143 108 0.320
actin cytoskeleton organization GO:0030036 206 0.316
nucleoside phosphate metabolic process GO:0006753 162 0.315
organic substance catabolic process GO:1901575 308 0.313
phototransduction GO:0007602 52 0.312
negative regulation of epidermal growth factor receptor signaling pathway GO:0042059 29 0.299
regulation of anatomical structure size GO:0090066 163 0.282
protein phosphorylation GO:0006468 169 0.277
guanosine containing compound catabolic process GO:1901069 74 0.271
leg disc development GO:0035218 92 0.269
signal transduction by phosphorylation GO:0023014 107 0.265
positive regulation of cell size GO:0045793 21 0.258
skin development GO:0043588 65 0.257
positive regulation of ras gtpase activity GO:0032320 36 0.256
regulation of cell morphogenesis GO:0022604 163 0.256
purine containing compound metabolic process GO:0072521 155 0.254
urogenital system development GO:0001655 72 0.254
regulation of nucleotide catabolic process GO:0030811 48 0.253
asymmetric neuroblast division GO:0055059 33 0.253
cell cell adhesion GO:0098609 26 0.252
positive regulation of gtp catabolic process GO:0033126 43 0.252
glycosyl compound catabolic process GO:1901658 112 0.252
epithelial cell development GO:0002064 274 0.245
nucleotide catabolic process GO:0009166 109 0.244
positive regulation of catabolic process GO:0009896 105 0.243
inorganic cation transmembrane transport GO:0098662 61 0.242
regulation of cellular response to stress GO:0080135 89 0.236
regulation of phosphorylation GO:0042325 147 0.236
Mouse
erbb signaling pathway GO:0038127 58 0.233
aromatic compound catabolic process GO:0019439 166 0.231
small gtpase mediated signal transduction GO:0007264 88 0.230
regulation of ras gtpase activity GO:0032318 38 0.227
synapse organization GO:0050808 196 0.226
purine containing compound catabolic process GO:0072523 112 0.225
positive regulation of nucleoside metabolic process GO:0045979 47 0.225
regulation of purine nucleotide metabolic process GO:1900542 62 0.224
purine ribonucleoside triphosphate metabolic process GO:0009205 119 0.223
protein localization GO:0008104 284 0.221
synaptic growth at neuromuscular junction GO:0051124 119 0.220
defense response GO:0006952 300 0.218
protein transport GO:0015031 155 0.216
defense response to other organism GO:0098542 225 0.216
positive regulation of molecular function GO:0044093 136 0.207
cell death GO:0008219 279 0.205
Mouse
programmed cell death GO:0012501 257 0.200
Mouse
ras protein signal transduction GO:0007265 88 0.200
gastrulation with mouth forming first GO:0001703 36 0.199
nucleobase containing compound catabolic process GO:0034655 165 0.196
organophosphate metabolic process GO:0019637 195 0.195
regulation of epidermal growth factor receptor signaling pathway GO:0042058 42 0.194
oocyte axis specification GO:0007309 108 0.194
regulation of jun kinase activity GO:0043506 8 0.194
positive regulation of protein phosphorylation GO:0001934 34 0.191
cellular nitrogen compound catabolic process GO:0044270 165 0.189
purine ribonucleoside triphosphate catabolic process GO:0009207 108 0.188
regulation of transmembrane transporter activity GO:0022898 6 0.185
embryonic ectodermal digestive tract morphogenesis GO:0048613 4 0.184
mapk cascade GO:0000165 107 0.181
determination of adult lifespan GO:0008340 137 0.180
single organism cell adhesion GO:0098602 47 0.179
eye photoreceptor cell differentiation GO:0001754 145 0.177
regulation of ras protein signal transduction GO:0046578 93 0.175
mrna processing GO:0006397 104 0.175
regulation of anatomical structure morphogenesis GO:0022603 242 0.173
Mouse
ribonucleoside metabolic process GO:0009119 127 0.171
negative regulation of phosphorylation GO:0042326 35 0.169
Mouse
small molecule metabolic process GO:0044281 305 0.167
positive regulation of jnk cascade GO:0046330 16 0.167
organic cyclic compound catabolic process GO:1901361 168 0.165
neuron projection guidance GO:0097485 241 0.164
ribonucleotide metabolic process GO:0009259 145 0.162
positive regulation of hydrolase activity GO:0051345 78 0.161
nucleotide metabolic process GO:0009117 161 0.159
positive regulation of developmental process GO:0051094 143 0.158
imaginal disc derived wing hair site selection GO:0035320 4 0.157
adult behavior GO:0030534 137 0.155
organelle fission GO:0048285 340 0.154
purine nucleoside catabolic process GO:0006152 112 0.153
death GO:0016265 284 0.152
Mouse
negative regulation of erbb signaling pathway GO:1901185 29 0.152
positive regulation of protein kinase activity GO:0045860 25 0.151
actomyosin structure organization GO:0031032 56 0.151
actin filament polymerization GO:0030041 27 0.150
ribonucleoside triphosphate catabolic process GO:0009203 108 0.150
wnt signaling pathway GO:0016055 98 0.149
open tracheal system development GO:0007424 204 0.148
carbohydrate derivative catabolic process GO:1901136 118 0.147
mitotic cell cycle phase transition GO:0044772 138 0.145
epidermal growth factor receptor signaling pathway GO:0007173 58 0.145
peptidyl threonine phosphorylation GO:0018107 2 0.145
Human
microtubule based movement GO:0007018 51 0.142
organelle localization GO:0051640 148 0.142
membrane organization GO:0061024 112 0.141
sensory perception of mechanical stimulus GO:0050954 72 0.139
positive regulation of synaptic growth at neuromuscular junction GO:0045887 26 0.138
regulation of transport GO:0051049 181 0.135
positive regulation of signaling GO:0023056 243 0.135
vesicle mediated transport GO:0016192 381 0.135
lipid localization GO:0010876 54 0.133
negative regulation of cellular metabolic process GO:0031324 382 0.133
Mouse
regulation of nucleotide metabolic process GO:0006140 62 0.131
planar cell polarity pathway involved in axis elongation GO:0003402 3 0.129
organophosphate catabolic process GO:0046434 112 0.129
eye development GO:0001654 323 0.127
regulation of dendrite development GO:0050773 37 0.126
response to wounding GO:0009611 94 0.125
ion transport GO:0006811 145 0.125
rubidium ion transport GO:0035826 1 0.123
metal ion transport GO:0030001 74 0.119
imaginal disc derived leg morphogenesis GO:0007480 80 0.119
positive regulation of apoptotic cell clearance GO:2000427 2 0.118
organonitrogen compound catabolic process GO:1901565 128 0.117
taxis GO:0042330 304 0.116
male gamete generation GO:0048232 201 0.114
regulation of cellular component movement GO:0051270 42 0.114
Human
cytoskeleton dependent cytokinesis GO:0061640 81 0.113
response to bacterium GO:0009617 198 0.113
positive regulation of phosphorylation GO:0042327 87 0.112
regulation of apoptotic process GO:0042981 130 0.111
protein maturation GO:0051604 71 0.110
photoreceptor cell development GO:0042461 96 0.109
maintenance of cell polarity GO:0030011 18 0.109
axon development GO:0061564 297 0.108
regulation of hydrolase activity GO:0051336 97 0.108
cell cell junction organization GO:0045216 55 0.107
Human Mouse
establishment of imaginal disc derived wing hair orientation GO:0001737 24 0.107
secretion by cell GO:0032940 101 0.105
response to organic substance GO:0010033 284 0.104
dendrite morphogenesis GO:0048813 199 0.103
activation of jun kinase activity GO:0007257 3 0.103
cell recognition GO:0008037 102 0.102
membrane invagination GO:0010324 11 0.102
establishment of protein localization GO:0045184 163 0.102
enzyme linked receptor protein signaling pathway GO:0007167 179 0.098
positive regulation of macromolecule metabolic process GO:0010604 405 0.098
regulation of ion transmembrane transport GO:0034765 27 0.097
transmembrane transport GO:0055085 139 0.096
purine nucleotide metabolic process GO:0006163 146 0.096
regulation of response to wounding GO:1903034 19 0.095
renal tubule development GO:0061326 64 0.095
regulation of synapse assembly GO:0051963 94 0.095
mucosal immune response GO:0002385 10 0.094
regulation of ion transport GO:0043269 39 0.094
establishment of organelle localization GO:0051656 122 0.094
establishment or maintenance of cytoskeleton polarity GO:0030952 44 0.094
positive regulation of signal transduction GO:0009967 223 0.092
purine nucleoside triphosphate catabolic process GO:0009146 108 0.092
nucleoside phosphate catabolic process GO:1901292 110 0.092
single organism cellular localization GO:1902580 180 0.091
localization of cell GO:0051674 257 0.089
Human
negative regulation of apoptotic process GO:0043066 63 0.087
regulation of proteasomal ubiquitin dependent protein catabolic process GO:0032434 37 0.086
head involution GO:0008258 35 0.085
macromolecule catabolic process GO:0009057 161 0.085
regulation of developmental growth GO:0048638 174 0.084
regulation of small gtpase mediated signal transduction GO:0051056 93 0.084
chemical homeostasis GO:0048878 92 0.083
protein targeting to nucleus GO:0044744 51 0.083
ribose phosphate metabolic process GO:0019693 145 0.083
exocrine system development GO:0035272 162 0.083
wound healing GO:0042060 75 0.081
regulation of immune response GO:0050776 118 0.081
Mouse
salivary gland development GO:0007431 162 0.080
protein modification process GO:0036211 438 0.079
activation of protein kinase activity GO:0032147 12 0.079
regulation of dendrite morphogenesis GO:0048814 28 0.079
compound eye photoreceptor fate commitment GO:0001752 36 0.078
regulation of organelle organization GO:0033043 196 0.077
purine ribonucleotide catabolic process GO:0009154 109 0.077
cellular macromolecule catabolic process GO:0044265 136 0.075
detection of abiotic stimulus GO:0009582 66 0.074
positive regulation of cell migration GO:0030335 2 0.074
regulation of cell cycle process GO:0010564 181 0.074
Human
regulation of synapse organization GO:0050807 110 0.072
pigmentation GO:0043473 75 0.072
neuromuscular junction development GO:0007528 149 0.072
sensory perception GO:0007600 196 0.072
compound eye retinal cell programmed cell death GO:0046667 23 0.072
posttranscriptional regulation of gene expression GO:0010608 145 0.071
regulation of programmed cell death GO:0043067 152 0.069
multi organism behavior GO:0051705 175 0.066
protein secretion GO:0009306 45 0.066
heterocycle catabolic process GO:0046700 166 0.066
regulation of vesicle mediated transport GO:0060627 59 0.066
inorganic ion transmembrane transport GO:0098660 73 0.065
phagocytosis GO:0006909 215 0.065
regulation of cell cell adhesion GO:0022407 21 0.065
asymmetric protein localization involved in cell fate determination GO:0045167 9 0.065
cell fate determination GO:0001709 91 0.065
motor neuron axon guidance GO:0008045 58 0.064
establishment of monopolar cell polarity GO:0061162 15 0.064
actin cytoskeleton reorganization GO:0031532 22 0.064
mushroom body development GO:0016319 70 0.064
defense response to bacterium GO:0042742 178 0.062
endomembrane system organization GO:0010256 119 0.062
positive regulation of transferase activity GO:0051347 26 0.062
developmental growth GO:0048589 280 0.062
determination of digestive tract left right asymmetry GO:0071907 6 0.062
apoptotic cell clearance GO:0043277 14 0.062
regulation of cellular localization GO:0060341 136 0.062
positive regulation of transport GO:0051050 92 0.061
response to biotic stimulus GO:0009607 294 0.061
body morphogenesis GO:0010171 2 0.061
organonitrogen compound metabolic process GO:1901564 318 0.060
negative regulation of signal transduction GO:0009968 206 0.059
epithelium migration GO:0090132 148 0.059
Human
anterior posterior pattern specification GO:0009952 136 0.059
response to other organism GO:0051707 293 0.058
immune system process GO:0002376 347 0.058
Mouse
developmental programmed cell death GO:0010623 138 0.058
protein deubiquitination GO:0016579 17 0.057
growth GO:0040007 359 0.057
multicellular organismal aging GO:0010259 140 0.056
ubiquitin dependent protein catabolic process GO:0006511 78 0.056
regulation of cellular component size GO:0032535 98 0.056
positive regulation of multicellular organismal process GO:0051240 143 0.055
maintenance of location GO:0051235 73 0.055
dendrite development GO:0016358 204 0.055
cellular protein catabolic process GO:0044257 83 0.055
regulation of multi organism process GO:0043900 131 0.055
positive regulation of protein localization to plasma membrane GO:1903078 3 0.053
negative regulation of autophagy GO:0010507 16 0.053
regulation of actin filament based process GO:0032970 42 0.053
regulation of protein localization GO:0032880 76 0.053
positive regulation of protein modification process GO:0031401 58 0.052
response to carbon dioxide GO:0010037 4 0.052
response to abiotic stimulus GO:0009628 341 0.052
Mouse
cation transmembrane transport GO:0098655 88 0.052
positive regulation of establishment of protein localization to plasma membrane GO:0090004 3 0.051
epithelial cell migration GO:0010631 148 0.051
Human
negative regulation of signaling GO:0023057 219 0.050
regulation of nuclear division GO:0051783 58 0.050
axis specification GO:0009798 167 0.050
compound eye morphogenesis GO:0001745 249 0.050
cell cycle phase transition GO:0044770 140 0.050
germ band shortening GO:0007390 19 0.050
activation of mapk activity GO:0000187 9 0.049
positive regulation of dendrite development GO:1900006 9 0.049
regulation of erk1 and erk2 cascade GO:0070372 39 0.049
regulation of cell projection organization GO:0031344 92 0.049
positive regulation of cell communication GO:0010647 250 0.049
negative regulation of cell differentiation GO:0045596 143 0.049
positive regulation of cell projection organization GO:0031346 29 0.048
positive regulation of purine nucleotide metabolic process GO:1900544 55 0.048
cytokinesis GO:0000910 90 0.048
Human
lipid storage GO:0019915 38 0.048
neuron projection extension GO:1990138 32 0.048
monocarboxylic acid transport GO:0015718 3 0.048
eye morphogenesis GO:0048592 260 0.047
modification dependent macromolecule catabolic process GO:0043632 79 0.047
nuclear transcribed mrna catabolic process deadenylation dependent decay GO:0000288 14 0.047
organic substance transport GO:0071702 257 0.047
regulation of synaptic transmission GO:0050804 69 0.047
proteolysis involved in cellular protein catabolic process GO:0051603 83 0.046
regulation of smoothened signaling pathway GO:0008589 28 0.046
positive regulation of multicellular organism growth GO:0040018 21 0.045
cell growth GO:0016049 108 0.044
embryonic pattern specification GO:0009880 174 0.044
epithelial tube morphogenesis GO:0060562 88 0.044
protein modification by small protein conjugation or removal GO:0070647 106 0.044
negative regulation of compound eye retinal cell programmed cell death GO:0046673 7 0.043
synapse assembly GO:0007416 143 0.042
oocyte microtubule cytoskeleton organization GO:0016325 35 0.042
positive regulation of cell motility GO:2000147 3 0.042
axon guidance GO:0007411 233 0.042
unidimensional cell growth GO:0009826 15 0.042
positive regulation of phagocytosis engulfment GO:0060100 1 0.042
spinal cord development GO:0021510 1 0.042
kidney epithelium development GO:0072073 3 0.042
regulation of actin cytoskeleton organization GO:0032956 42 0.042
regulation of cytoskeleton organization GO:0051493 89 0.041
heart development GO:0007507 82 0.041
establishment of vesicle localization GO:0051650 51 0.041
regulation of erbb signaling pathway GO:1901184 42 0.041
axonogenesis GO:0007409 290 0.040
cell junction assembly GO:0034329 42 0.040
Human Mouse
renal system development GO:0072001 72 0.040
negative regulation of intracellular signal transduction GO:1902532 57 0.040
negative regulation of cellular component organization GO:0051129 108 0.040
asymmetric stem cell division GO:0098722 49 0.039
intracellular signal transduction GO:0035556 300 0.039
detection of external stimulus GO:0009581 66 0.038
reproductive behavior GO:0019098 122 0.038
epithelial cell morphogenesis involved in gastrulation GO:0003381 7 0.038
regulation of transmembrane receptor protein serine threonine kinase signaling pathway GO:0090092 38 0.038
cardiovascular system development GO:0072358 82 0.038
cilium organization GO:0044782 41 0.038
regulation of cell size GO:0008361 63 0.038
regulation of mitosis GO:0007088 56 0.038
proteasome mediated ubiquitin dependent protein catabolic process GO:0043161 54 0.037
salivary gland morphogenesis GO:0007435 145 0.037
single organismal cell cell adhesion GO:0016337 45 0.037
regulation of kinase activity GO:0043549 53 0.037
Mouse
gland development GO:0048732 191 0.037
gastrulation GO:0007369 70 0.036
homeostatic process GO:0042592 199 0.036
Mouse
regulation of compound eye retinal cell programmed cell death GO:0046669 18 0.036
transmembrane receptor protein serine threonine kinase signaling pathway GO:0007178 65 0.036
mrna metabolic process GO:0016071 124 0.035
regulation of nervous system development GO:0051960 248 0.035
regulation of transferase activity GO:0051338 58 0.035
Mouse
regulation of system process GO:0044057 36 0.035
positive regulation of mapk cascade GO:0043410 63 0.034
digestive tract morphogenesis GO:0048546 127 0.034
meiotic cell cycle GO:0051321 171 0.034
regulation of cell division GO:0051302 72 0.034
Human
cell elongation involved in imaginal disc derived wing morphogenesis GO:0090254 5 0.034
aging GO:0007568 143 0.033
negative regulation of cellular protein metabolic process GO:0032269 85 0.033
Mouse
bmp signaling pathway involved in malpighian tubule cell chemotaxis GO:0061353 3 0.033
positive regulation of immune system process GO:0002684 68 0.033
defense response to gram negative bacterium GO:0050829 94 0.033
regionalization GO:0003002 416 0.033
activation of rac gtpase activity GO:0032863 3 0.033
protein processing GO:0016485 68 0.033
spermatogenesis GO:0007283 200 0.033
axonal fasciculation GO:0007413 12 0.032
regulation of cellular amino acid metabolic process GO:0006521 0 0.032
protein complex assembly GO:0006461 200 0.032
immune response GO:0006955 246 0.032
Mouse
regulation of endocytosis GO:0030100 37 0.032
regulation of mapk cascade GO:0043408 92 0.031
protein modification by small protein removal GO:0070646 28 0.031
regulation of r7 cell differentiation GO:0045676 15 0.031
regulation of microtubule based process GO:0032886 49 0.031
g protein coupled receptor signaling pathway GO:0007186 136 0.031
spindle organization GO:0007051 253 0.031
single organism behavior GO:0044708 391 0.031
initiation of dorsal closure GO:0007392 12 0.030
canonical wnt signaling pathway GO:0060070 21 0.030
nuclear division GO:0000280 332 0.030
compound eye photoreceptor cell differentiation GO:0001751 140 0.030
regulation of cell development GO:0060284 215 0.030
carbohydrate derivative metabolic process GO:1901135 217 0.030
gland morphogenesis GO:0022612 145 0.030
muscle cell fate specification GO:0042694 7 0.029
leg disc morphogenesis GO:0007478 80 0.029
sensory organ morphogenesis GO:0090596 260 0.029
immune response activating signal transduction GO:0002757 2 0.029
spindle assembly GO:0051225 80 0.029
anion transport GO:0006820 41 0.029
regulation of response to biotic stimulus GO:0002831 63 0.029
maternal determination of anterior posterior axis embryo GO:0008358 74 0.029
regulation of immune effector process GO:0002697 52 0.028
Mouse
positive regulation of dendrite morphogenesis GO:0050775 9 0.028
developmental growth involved in morphogenesis GO:0060560 65 0.028
actin filament bundle organization GO:0061572 28 0.028
negative regulation of protein metabolic process GO:0051248 85 0.028
Mouse
cellular response to carbon dioxide GO:0071244 2 0.027
cytoplasmic sequestering of protein GO:0051220 4 0.027
regulation of cell cycle GO:0051726 291 0.027
Human
apoptotic process GO:0006915 159 0.027
Mouse
carboxylic acid metabolic process GO:0019752 92 0.027
proteasomal protein catabolic process GO:0010498 59 0.026
immune response regulating signaling pathway GO:0002764 2 0.026
actin filament organization GO:0007015 126 0.026
vesicle localization GO:0051648 55 0.026
regulation of map kinase activity GO:0043405 17 0.026
negative regulation of phosphate metabolic process GO:0045936 45 0.026
Mouse
negative regulation of protein tyrosine kinase activity GO:0061099 5 0.026
multicellular organism growth GO:0035264 46 0.026
negative regulation of protein modification process GO:0031400 29 0.026
Mouse
peptidyl threonine modification GO:0018210 3 0.026
Human
regulation of actin filament length GO:0030832 27 0.026
cellular response to chemical stimulus GO:0070887 199 0.025
cellular protein localization GO:0034613 160 0.025
negative regulation of programmed cell death GO:0043069 72 0.025
sarcomere organization GO:0045214 26 0.025
collateral sprouting GO:0048668 3 0.025
detection of light stimulus GO:0009583 58 0.025
negative regulation of kinase activity GO:0033673 16 0.025
Mouse
regulation of hemocyte proliferation GO:0035206 37 0.025
positive regulation of apoptotic process GO:0043065 47 0.025

Pkn disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in fly and predicted with the fly functional network.

Disease DO term ID Size Probability Func Analog Org
diabetes mellitus DOID:9351 0 0.045
type 2 diabetes mellitus DOID:9352 0 0.045
disease of metabolism DOID:0014667 0 0.045
carbohydrate metabolism disease DOID:0050013 0 0.045
glucose metabolism disease DOID:4194 0 0.045
acquired metabolic disease DOID:0060158 0 0.045
disease of anatomical entity DOID:7 0 0.025
nervous system disease DOID:863 0 0.025