Drosophila melanogaster

94 known processes

pain (Dmel_CG15860)

painless

(Aliases: Dmel\CG15860,CG15860,CT31987,EP2251)

pain biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
detection of stimulus GO:0051606 156 0.996
single organism behavior GO:0044708 391 0.990
g protein coupled receptor signaling pathway GO:0007186 136 0.830
male mating behavior GO:0060179 70 0.771
sensory perception GO:0007600 196 0.760
detection of external stimulus GO:0009581 66 0.662
ion transmembrane transport GO:0034220 122 0.622
sensory perception of chemical stimulus GO:0007606 116 0.601
cell adhesion involved in heart morphogenesis GO:0061343 12 0.542
detection of abiotic stimulus GO:0009582 66 0.510
multi multicellular organism process GO:0044706 123 0.491
response to abiotic stimulus GO:0009628 341 0.457
synaptic transmission GO:0007268 288 0.424
behavioral response to pain GO:0048266 3 0.421
reproductive behavior GO:0019098 122 0.400
localization of cell GO:0051674 257 0.382
cellular response to abiotic stimulus GO:0071214 58 0.328
neurological system process GO:0050877 358 0.303
multicellular organismal reproductive behavior GO:0033057 110 0.291
sensory perception of mechanical stimulus GO:0050954 72 0.289
detection of light stimulus GO:0009583 58 0.275
response to temperature stimulus GO:0009266 106 0.271
detection of chemical stimulus GO:0009593 93 0.254
ribose phosphate biosynthetic process GO:0046390 28 0.250
morphogenesis of an epithelium GO:0002009 276 0.248
response to organic substance GO:0010033 284 0.217
response to radiation GO:0009314 155 0.217
thermotaxis GO:0043052 16 0.197
establishment of planar polarity GO:0001736 87 0.197
ion transport GO:0006811 145 0.195
sensory perception of taste GO:0050909 25 0.193
phototransduction GO:0007602 52 0.190
detection of stimulus involved in sensory perception GO:0050906 92 0.182
locomotory behavior GO:0007626 176 0.179
mating behavior GO:0007617 106 0.173
response to inorganic substance GO:0010035 44 0.170
germ cell migration GO:0008354 43 0.161
multi organism reproductive behavior GO:0044705 121 0.160
multi organism behavior GO:0051705 175 0.160
tissue morphogenesis GO:0048729 297 0.147
single organism biosynthetic process GO:0044711 206 0.146
nucleotide metabolic process GO:0009117 161 0.145
transmembrane transport GO:0055085 139 0.143
organonitrogen compound biosynthetic process GO:1901566 117 0.143
response to mechanical stimulus GO:0009612 28 0.137
response to oxygen containing compound GO:1901700 200 0.134
cellular response to chemical stimulus GO:0070887 199 0.130
courtship behavior GO:0007619 68 0.121
organophosphate metabolic process GO:0019637 195 0.116
heart process GO:0003015 37 0.114
morphogenesis of a polarized epithelium GO:0001738 93 0.106
organic acid metabolic process GO:0006082 103 0.105
chemosensory behavior GO:0007635 106 0.100
heart development GO:0007507 82 0.099
negative regulation of response to stimulus GO:0048585 258 0.096
response to light stimulus GO:0009416 124 0.093
organonitrogen compound metabolic process GO:1901564 318 0.090
larval behavior GO:0030537 42 0.082
carboxylic acid metabolic process GO:0019752 92 0.082
response to heat GO:0009408 63 0.081
response to nutrient levels GO:0031667 114 0.077
nucleobase containing compound catabolic process GO:0034655 165 0.075
feeding behavior GO:0007631 50 0.073
ribose phosphate metabolic process GO:0019693 145 0.071
small molecule metabolic process GO:0044281 305 0.071
regulation of response to stress GO:0080134 200 0.067
mating GO:0007618 120 0.065
actin cytoskeleton organization GO:0030036 206 0.064
heterocycle catabolic process GO:0046700 166 0.064
detection of mechanical stimulus involved in sensory perception of pain GO:0050966 2 0.064
male courtship behavior GO:0008049 63 0.059
heart morphogenesis GO:0003007 32 0.058
ribonucleotide metabolic process GO:0009259 145 0.057
limb development GO:0060173 1 0.057
response to organic cyclic compound GO:0014070 89 0.056
memory GO:0007613 94 0.056
actin filament based process GO:0030029 220 0.055
post embryonic appendage morphogenesis GO:0035120 385 0.055
cyclic nucleotide metabolic process GO:0009187 28 0.055
nucleoside phosphate metabolic process GO:0006753 162 0.055
cell migration GO:0016477 238 0.055
sensory perception of touch GO:0050975 11 0.054
cyclic nucleotide biosynthetic process GO:0009190 25 0.053
cation transport GO:0006812 110 0.051
olfactory behavior GO:0042048 97 0.051
cyclic purine nucleotide metabolic process GO:0052652 25 0.050
monovalent inorganic cation transport GO:0015672 40 0.049
epiboly GO:0090504 2 0.047
purine ribonucleotide metabolic process GO:0009150 145 0.047
glycosyl compound catabolic process GO:1901658 112 0.045
oxoacid metabolic process GO:0043436 103 0.045
lipid metabolic process GO:0006629 121 0.045
vesicle mediated transport GO:0016192 381 0.044
cellular amino acid metabolic process GO:0006520 61 0.044
asymmetric stem cell division GO:0098722 49 0.044
homeostatic process GO:0042592 199 0.043
negative regulation of cell differentiation GO:0045596 143 0.043
ventral cord development GO:0007419 16 0.043
organic substance transport GO:0071702 257 0.042
response to oxidative stress GO:0006979 86 0.042
regulation of heart contraction GO:0008016 21 0.042
nucleobase containing small molecule metabolic process GO:0055086 174 0.041
gravitaxis GO:0042332 26 0.041
organophosphate biosynthetic process GO:0090407 46 0.041
cellular response to nutrient levels GO:0031669 62 0.040
response to pain GO:0048265 3 0.040
stem cell division GO:0017145 69 0.039
carbohydrate derivative metabolic process GO:1901135 217 0.039
cell junction organization GO:0034330 57 0.039
response to endogenous stimulus GO:0009719 119 0.038
lateral inhibition GO:0046331 206 0.038
response to carbon dioxide GO:0010037 4 0.037
posttranscriptional regulation of gene expression GO:0010608 145 0.037
nucleoside phosphate biosynthetic process GO:1901293 34 0.037
cell cell junction assembly GO:0007043 38 0.037
purine containing compound metabolic process GO:0072521 155 0.036
learning or memory GO:0007611 141 0.036
taxis GO:0042330 304 0.036
sensory perception of pain GO:0019233 4 0.036
imaginal disc derived appendage morphogenesis GO:0035114 395 0.034
appendage morphogenesis GO:0035107 397 0.034
purine containing compound biosynthetic process GO:0072522 30 0.034
carbohydrate derivative biosynthetic process GO:1901137 85 0.033
cellular response to starvation GO:0009267 61 0.032
ribonucleoside triphosphate catabolic process GO:0009203 108 0.032
dna metabolic process GO:0006259 227 0.032
establishment of tissue polarity GO:0007164 87 0.032
head development GO:0060322 135 0.032
inter male aggressive behavior GO:0002121 60 0.032
cell proliferation GO:0008283 299 0.031
water homeostasis GO:0030104 3 0.030
oocyte maturation GO:0001556 3 0.030
embryonic morphogenesis GO:0048598 206 0.030
purine nucleoside triphosphate catabolic process GO:0009146 108 0.030
negative regulation of developmental process GO:0051093 201 0.030
cellular response to oxygen containing compound GO:1901701 79 0.030
larval feeding behavior GO:0030536 15 0.030
regulation of cyclic nucleotide biosynthetic process GO:0030802 13 0.030
cation transmembrane transport GO:0098655 88 0.030
response to starvation GO:0042594 97 0.030
amine metabolic process GO:0009308 12 0.029
mucosal immune response GO:0002385 10 0.029
developmental programmed cell death GO:0010623 138 0.029
locomotor rhythm GO:0045475 56 0.028
purine containing compound catabolic process GO:0072523 112 0.028
meiotic cell cycle process GO:1903046 132 0.028
limb morphogenesis GO:0035108 1 0.027
septate junction assembly GO:0019991 26 0.027
establishment of glial blood brain barrier GO:0060857 14 0.027
organic cyclic compound catabolic process GO:1901361 168 0.027
regulation of synaptic transmission GO:0050804 69 0.027
regulation of membrane potential GO:0042391 35 0.026
response to gravity GO:0009629 26 0.026
cellular ketone metabolic process GO:0042180 24 0.026
peptide biosynthetic process GO:0043043 42 0.026
apoptotic process involved in morphogenesis GO:0060561 3 0.026
regulation of cellular amine metabolic process GO:0033238 3 0.026
response to monosaccharide GO:0034284 4 0.026
appendage development GO:0048736 401 0.026
learning GO:0007612 75 0.026
circulatory system development GO:0072359 82 0.025
biological adhesion GO:0022610 138 0.025
cation homeostasis GO:0055080 51 0.025
morphogenesis of embryonic epithelium GO:0016331 94 0.025
ribonucleoside metabolic process GO:0009119 127 0.025
enzyme linked receptor protein signaling pathway GO:0007167 179 0.025
aromatic compound catabolic process GO:0019439 166 0.024
gonad development GO:0008406 50 0.024
response to extracellular stimulus GO:0009991 116 0.024
larval locomotory behavior GO:0008345 27 0.024
regulation of ion transport GO:0043269 39 0.023
establishment of blood brain barrier GO:0060856 16 0.023
transmembrane receptor protein tyrosine kinase signaling pathway GO:0007169 116 0.023
chromosome organization GO:0051276 360 0.023
adult behavior GO:0030534 137 0.023
apical junction assembly GO:0043297 32 0.022
neuropeptide signaling pathway GO:0007218 45 0.022
indole containing compound biosynthetic process GO:0042435 4 0.022
wing disc morphogenesis GO:0007472 344 0.022
purine ribonucleoside metabolic process GO:0046128 127 0.022
sodium ion transport GO:0006814 22 0.021
catabolic process GO:0009056 409 0.021
cellular response to extracellular stimulus GO:0031668 64 0.021
synaptic vesicle localization GO:0097479 53 0.021
heart contraction GO:0060047 26 0.021
cellular catabolic process GO:0044248 372 0.021
myotube cell development GO:0014904 3 0.021
purine nucleoside catabolic process GO:0006152 112 0.020
embryonic heart tube development GO:0035050 22 0.020
detection of chemical stimulus involved in sensory perception GO:0050907 75 0.020
nucleoside catabolic process GO:0009164 112 0.020
cell division GO:0051301 248 0.020
cellular response to water stimulus GO:0071462 2 0.020
ameboidal type cell migration GO:0001667 151 0.020
response to alcohol GO:0097305 95 0.020
cellular amine metabolic process GO:0044106 12 0.020
regulation of localization GO:0032879 275 0.020
nucleoside phosphate catabolic process GO:1901292 110 0.020
positive regulation of response to stimulus GO:0048584 323 0.020
regulation of cell shape GO:0008360 113 0.020
organophosphate catabolic process GO:0046434 112 0.019
dopamine receptor signaling pathway GO:0007212 4 0.019
cellular response to dna damage stimulus GO:0006974 223 0.019
positive regulation of signaling GO:0023056 243 0.019
catecholamine biosynthetic process GO:0042423 3 0.019
embryo development ending in birth or egg hatching GO:0009792 152 0.018
cell cell signaling involved in cell fate commitment GO:0045168 210 0.018
inorganic cation transmembrane transport GO:0098662 61 0.018
metal ion transport GO:0030001 74 0.018
salivary gland development GO:0007431 162 0.018
negative regulation of rna metabolic process GO:0051253 251 0.018
nucleoside triphosphate catabolic process GO:0009143 108 0.018
regulation of multi organism process GO:0043900 131 0.018
immune response GO:0006955 246 0.018
regulation of cellular ketone metabolic process GO:0010565 3 0.018
gastrulation involving germ band extension GO:0010004 36 0.018
ribonucleoside triphosphate metabolic process GO:0009199 119 0.018
organic substance catabolic process GO:1901575 308 0.018
negative regulation of biosynthetic process GO:0009890 277 0.018
response to bacterium GO:0009617 198 0.018
cellular response to organic substance GO:0071310 132 0.018
phagocytosis GO:0006909 215 0.018
negative regulation of cellular metabolic process GO:0031324 382 0.018
negative regulation of nitrogen compound metabolic process GO:0051172 265 0.018
long term memory GO:0007616 62 0.017
mrna metabolic process GO:0016071 124 0.017
muscle tissue morphogenesis GO:0060415 2 0.017
sensory organ morphogenesis GO:0090596 260 0.017
negative regulation of macromolecule biosynthetic process GO:0010558 270 0.017
anatomical structure homeostasis GO:0060249 97 0.017
response to ethanol GO:0045471 59 0.017
body morphogenesis GO:0010171 2 0.017
gastrulation with mouth forming first GO:0001703 36 0.016
regulation of organ morphogenesis GO:2000027 78 0.016
regulation of purine nucleotide metabolic process GO:1900542 62 0.016
central nervous system development GO:0007417 201 0.016
regulation of nucleotide metabolic process GO:0006140 62 0.016
sensory perception of smell GO:0007608 80 0.016
macromolecule catabolic process GO:0009057 161 0.016
camera type eye development GO:0043010 4 0.016
regulation of phosphorus metabolic process GO:0051174 210 0.016
dopamine biosynthetic process GO:0042416 3 0.016
positive regulation of catalytic activity GO:0043085 118 0.016
single organism catabolic process GO:0044712 228 0.016
cell death GO:0008219 279 0.016
regulation of establishment of planar polarity GO:0090175 22 0.015
nucleoside metabolic process GO:0009116 127 0.015
drinking behavior GO:0042756 2 0.015
gland morphogenesis GO:0022612 145 0.015
wound healing spreading of cells GO:0044319 2 0.015
nucleoside triphosphate metabolic process GO:0009141 120 0.015
circulatory system process GO:0003013 37 0.015
apoptotic process GO:0006915 159 0.015
cellular nitrogen compound catabolic process GO:0044270 165 0.015
potassium ion transport GO:0006813 20 0.015
regulation of transport GO:0051049 181 0.015
negative regulation of gene expression GO:0010629 387 0.015
ribonucleoside catabolic process GO:0042454 112 0.015
regulation of epithelial cell proliferation GO:0050678 4 0.015
response to trehalose GO:0010353 3 0.015
imaginal disc derived wing morphogenesis GO:0007476 337 0.015
purine ribonucleoside triphosphate metabolic process GO:0009205 119 0.015
cellular response to external stimulus GO:0071496 66 0.015
response to organonitrogen compound GO:0010243 75 0.014
negative regulation of nucleobase containing compound metabolic process GO:0045934 261 0.014
aromatic amino acid family metabolic process GO:0009072 3 0.014
neurotransmitter transport GO:0006836 37 0.014
organonitrogen compound catabolic process GO:1901565 128 0.014
chromatin modification GO:0016568 147 0.014
response to decreased oxygen levels GO:0036293 58 0.014
purine nucleotide catabolic process GO:0006195 109 0.014
response to nitrogen compound GO:1901698 90 0.014
synaptic vesicle transport GO:0048489 50 0.014
regulation of cell cycle process GO:0010564 181 0.014
purine nucleoside triphosphate metabolic process GO:0009144 119 0.014
wound healing spreading of epidermal cells GO:0035313 1 0.014
tissue homeostasis GO:0001894 36 0.014
purine nucleotide metabolic process GO:0006163 146 0.014
molting cycle chitin based cuticle GO:0007591 56 0.014
regulation of multicellular organismal development GO:2000026 414 0.014
embryonic organ development GO:0048568 50 0.014
regulation of catabolic process GO:0009894 170 0.014
regulation of anatomical structure morphogenesis GO:0022603 242 0.014
meiotic cell cycle GO:0051321 171 0.014
establishment of protein localization GO:0045184 163 0.014
cranial nerve development GO:0021545 1 0.014
response to lipopolysaccharide GO:0032496 4 0.014
stem cell differentiation GO:0048863 117 0.013
cellular response to radiation GO:0071478 52 0.013
rhythmic behavior GO:0007622 76 0.013
humoral immune response GO:0006959 117 0.013
sensory perception of salty taste GO:0050914 3 0.013
development of primary sexual characteristics GO:0045137 50 0.013
tube development GO:0035295 244 0.013
response to glucose GO:0009749 2 0.013
response to other organism GO:0051707 293 0.013
intracellular signal transduction GO:0035556 300 0.013
protein localization GO:0008104 284 0.013
protein transport GO:0015031 155 0.013
response to reactive oxygen species GO:0000302 24 0.013
negative regulation of cell communication GO:0010648 223 0.013
regulation of immune system process GO:0002682 176 0.013
camera type eye morphogenesis GO:0048593 2 0.013
nucleotide catabolic process GO:0009166 109 0.013
cellular response to nitrogen compound GO:1901699 51 0.013
regulation of cellular amino acid metabolic process GO:0006521 0 0.013
connective tissue development GO:0061448 3 0.013
response to light intensity GO:0009642 6 0.013
response to osmotic stress GO:0006970 14 0.013
purine nucleoside metabolic process GO:0042278 127 0.013
purine ribonucleoside triphosphate catabolic process GO:0009207 108 0.013
molting cycle process GO:0022404 29 0.013
regulation of phosphate metabolic process GO:0019220 210 0.012
skeletal muscle fiber development GO:0048741 3 0.012
camp biosynthetic process GO:0006171 17 0.012
response to carbohydrate GO:0009743 15 0.012
establishment of vesicle localization GO:0051650 51 0.012
positive regulation of signal transduction GO:0009967 223 0.012
purine nucleotide biosynthetic process GO:0006164 29 0.012
lipid localization GO:0010876 54 0.012
stem cell proliferation GO:0072089 88 0.012
negative regulation of rna biosynthetic process GO:1902679 240 0.012
multicellular organismal aging GO:0010259 140 0.012
tube morphogenesis GO:0035239 191 0.012
regulation of programmed cell death GO:0043067 152 0.012
regulation of heart morphogenesis GO:2000826 3 0.012
establishment of localization in cell GO:0051649 402 0.012
epiboly involved in wound healing GO:0090505 2 0.012
phosphorylation GO:0016310 294 0.011
regulation of cell death GO:0010941 173 0.011
purine ribonucleotide catabolic process GO:0009154 109 0.011
compound eye retinal cell programmed cell death GO:0046667 23 0.011
cell junction assembly GO:0034329 42 0.011
regulation of protein transport GO:0051223 57 0.011
detection of external biotic stimulus GO:0098581 2 0.011
columnar cuboidal epithelial cell differentiation GO:0002065 256 0.011
endocytosis GO:0006897 310 0.011
regulation of feeding behavior GO:0060259 16 0.011
negative regulation of cellular biosynthetic process GO:0031327 277 0.011
determination of adult lifespan GO:0008340 137 0.011
positive regulation of cell communication GO:0010647 250 0.011
immune response regulating signaling pathway GO:0002764 2 0.011
membrane lipid metabolic process GO:0006643 22 0.011
purine ribonucleoside catabolic process GO:0046130 112 0.011
cell cell junction organization GO:0045216 55 0.011
developmental maturation GO:0021700 172 0.011
imaginal disc derived appendage development GO:0048737 399 0.011
kidney development GO:0001822 3 0.011
positive regulation of macromolecule biosynthetic process GO:0010557 283 0.010
mechanosensory behavior GO:0007638 12 0.010
adenylate cyclase activating g protein coupled receptor signaling pathway GO:0007189 9 0.010
cellular response to carbon dioxide GO:0071244 2 0.010
tyrosine metabolic process GO:0006570 1 0.010
response to salt stress GO:0009651 11 0.010
cardiovascular system development GO:0072358 82 0.010
negative regulation of intracellular signal transduction GO:1902532 57 0.010
salt aversion GO:0035199 3 0.010
camp metabolic process GO:0046058 19 0.010
neuromuscular synaptic transmission GO:0007274 67 0.010
epithelial cell differentiation GO:0030855 322 0.010
secondary metabolic process GO:0019748 75 0.010
immune system process GO:0002376 347 0.010
ion homeostasis GO:0050801 55 0.010
ectopic germ cell programmed cell death GO:0035234 8 0.010
positive regulation of molecular function GO:0044093 136 0.010
defense response to other organism GO:0098542 225 0.010
cell maturation GO:0048469 144 0.010
response to oxygen levels GO:0070482 59 0.010
reproductive structure development GO:0048608 74 0.010
sex differentiation GO:0007548 81 0.010
dna conformation change GO:0071103 105 0.010
establishment of organelle localization GO:0051656 122 0.010

pain disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in fly and predicted with the fly functional network.

Disease DO term ID Size Probability Func Analog Org
disease of anatomical entity DOID:7 0 0.063
renal tubular transport disease DOID:447 0 0.052
kidney disease DOID:557 0 0.052
urinary system disease DOID:18 0 0.052
respiratory system disease DOID:1579 0 0.042
disease of metabolism DOID:0014667 0 0.031
lower respiratory tract disease DOID:0050161 0 0.024
bronchial disease DOID:1176 0 0.024
muscular disease DOID:0080000 0 0.021
musculoskeletal system disease DOID:17 0 0.021
muscle tissue disease DOID:66 0 0.021
bronchiectasis DOID:9563 0 0.015
sensory system disease DOID:0050155 0 0.015
nervous system disease DOID:863 0 0.015
liddle syndrome DOID:0050477 0 0.015
disease of cellular proliferation DOID:14566 0 0.014
cancer DOID:162 0 0.012
organ system cancer DOID:0050686 0 0.012
bone disease DOID:0080001 0 0.012
connective tissue disease DOID:65 0 0.012
inherited metabolic disorder DOID:655 0 0.011