Drosophila melanogaster

64 known processes

Pka-R2 (Dmel_CG15862)

cAMP-dependent protein kinase R2

(Aliases: BcDNA:GM01761,pkA,Cos,PKA RII,cos1,Pka-RII,Dmel\CG15862,CG15862,pka-RII,PKa-R2,PKA,Cos1,RII,RII[[DR]],PKA-R2,PKA-RII,Cos-1,Epa)

Pka-R2 biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
taxis GO:0042330 304 0.788
neuron projection guidance GO:0097485 241 0.675
single organism behavior GO:0044708 391 0.520
behavioral response to ethanol GO:0048149 49 0.466
chemotaxis GO:0006935 249 0.395
actin filament based process GO:0030029 220 0.358
appendage development GO:0048736 401 0.305
axon development GO:0061564 297 0.277
negative regulation of cellular metabolic process GO:0031324 382 0.260
Human
axon guidance GO:0007411 233 0.259
axonogenesis GO:0007409 290 0.254
imaginal disc derived appendage morphogenesis GO:0035114 395 0.253
motor neuron axon guidance GO:0008045 58 0.252
regulation of neurogenesis GO:0050767 158 0.246
neurological system process GO:0050877 358 0.244
Mouse
neuron recognition GO:0008038 101 0.234
eye development GO:0001654 323 0.173
cell recognition GO:0008037 102 0.168
regulation of nervous system development GO:0051960 248 0.163
organelle assembly GO:0070925 198 0.161
actin cytoskeleton organization GO:0030036 206 0.158
positive regulation of biosynthetic process GO:0009891 316 0.153
regulation of transcription from rna polymerase ii promoter GO:0006357 378 0.148
adult behavior GO:0030534 137 0.147
imaginal disc derived appendage development GO:0048737 399 0.134
appendage morphogenesis GO:0035107 397 0.133
g protein coupled receptor signaling pathway GO:0007186 136 0.127
regulation of secretion by cell GO:1903530 39 0.124
cognition GO:0050890 141 0.117
Mouse
regulation of anatomical structure size GO:0090066 163 0.116
locomotor rhythm GO:0045475 56 0.115
single organism biosynthetic process GO:0044711 206 0.112
developmental growth GO:0048589 280 0.112
ovarian follicle cell migration GO:0007297 121 0.110
l glutamate import GO:0051938 1 0.109
homeostatic process GO:0042592 199 0.107
regulation of erbb signaling pathway GO:1901184 42 0.103
epithelium migration GO:0090132 148 0.100
wing disc morphogenesis GO:0007472 344 0.098
vesicle mediated transport GO:0016192 381 0.092
negative regulation of erbb signaling pathway GO:1901185 29 0.091
actin filament based movement GO:0030048 26 0.090
positive regulation of gene expression GO:0010628 290 0.089
tissue migration GO:0090130 155 0.087
erbb signaling pathway GO:0038127 58 0.081
single organism carbohydrate metabolic process GO:0044723 72 0.080
long term memory GO:0007616 62 0.076
dendrite development GO:0016358 204 0.072
transcription from rna polymerase ii promoter GO:0006366 368 0.072
neuropeptide signaling pathway GO:0007218 45 0.071
cellular catabolic process GO:0044248 372 0.069
macromolecular complex assembly GO:0065003 256 0.069
Rat
microtubule based transport GO:0010970 42 0.069
epidermis development GO:0008544 65 0.069
circadian behavior GO:0048512 76 0.069
renal system process GO:0003014 12 0.068
epidermal growth factor receptor signaling pathway GO:0007173 58 0.067
regulation of multicellular organismal development GO:2000026 414 0.067
positive regulation of cell communication GO:0010647 250 0.066
negative regulation of cellular macromolecule biosynthetic process GO:2000113 267 0.066
positive regulation of multicellular organismal process GO:0051240 143 0.065
negative regulation of transcription dna templated GO:0045892 237 0.064
photoreceptor cell development GO:0042461 96 0.063
regulation of molecular function GO:0065009 217 0.063
Human Mouse Rat
compound eye morphogenesis GO:0001745 249 0.062
regulation of secretion GO:0051046 44 0.062
germarium derived egg chamber formation GO:0007293 101 0.062
positive regulation of rna biosynthetic process GO:1902680 266 0.061
response to abiotic stimulus GO:0009628 341 0.060
locomotory behavior GO:0007626 176 0.059
response to light stimulus GO:0009416 124 0.057
compound eye photoreceptor cell differentiation GO:0001751 140 0.056
positive regulation of nitrogen compound metabolic process GO:0051173 354 0.056
regionalization GO:0003002 416 0.056
regulation of developmental growth GO:0048638 174 0.056
positive regulation of signal transduction GO:0009967 223 0.055
response to alcohol GO:0097305 95 0.055
response to radiation GO:0009314 155 0.054
male courtship behavior veined wing extension GO:0048065 22 0.054
oocyte development GO:0048599 124 0.053
compound eye development GO:0048749 307 0.053
positive regulation of rna metabolic process GO:0051254 271 0.052
sensory perception of mechanical stimulus GO:0050954 72 0.052
embryonic development via the syncytial blastoderm GO:0001700 148 0.051
regulation of localization GO:0032879 275 0.051
defense response to other organism GO:0098542 225 0.051
immune response regulating signaling pathway GO:0002764 2 0.051
negative regulation of cell communication GO:0010648 223 0.050
small molecule metabolic process GO:0044281 305 0.050
Mouse
regulation of growth GO:0040008 233 0.049
transmembrane transport GO:0055085 139 0.048
male courtship behavior veined wing generated song production GO:0045433 20 0.047
centrosome cycle GO:0007098 137 0.047
epithelial cell migration GO:0010631 148 0.047
regulation of cell development GO:0060284 215 0.047
catabolic process GO:0009056 409 0.046
ameboidal type cell migration GO:0001667 151 0.046
cell motility GO:0048870 251 0.046
localization of cell GO:0051674 257 0.045
regulation of tube size GO:0035150 46 0.045
oocyte differentiation GO:0009994 145 0.045
positive regulation of signaling GO:0023056 243 0.045
renal tubule development GO:0061326 64 0.045
negative regulation of gene expression GO:0010629 387 0.044
immune response activating signal transduction GO:0002757 2 0.044
regulation of transport GO:0051049 181 0.043
cation transmembrane transport GO:0098655 88 0.042
cellular component assembly involved in morphogenesis GO:0010927 151 0.042
positive regulation of molecular function GO:0044093 136 0.041
regulation of epidermal growth factor receptor signaling pathway GO:0042058 42 0.041
regulation of cell differentiation GO:0045595 302 0.040
phosphorylation GO:0016310 294 0.040
Human Mouse Rat
positive regulation of transport GO:0051050 92 0.040
multicellular organism growth GO:0035264 46 0.040
organelle fission GO:0048285 340 0.039
response to organic substance GO:0010033 284 0.039
eye morphogenesis GO:0048592 260 0.038
negative regulation of rna metabolic process GO:0051253 251 0.038
striated muscle cell differentiation GO:0051146 90 0.038
intracellular signal transduction GO:0035556 300 0.037
positive regulation of cellular biosynthetic process GO:0031328 316 0.037
signal release GO:0023061 49 0.037
negative regulation of epidermal growth factor receptor signaling pathway GO:0042059 29 0.037
photoreceptor cell differentiation GO:0046530 170 0.037
dendrite morphogenesis GO:0048813 199 0.036
cellular protein modification process GO:0006464 438 0.036
Human Mouse Rat
negative regulation of nucleic acid templated transcription GO:1903507 240 0.036
cellular response to carbohydrate stimulus GO:0071322 4 0.036
negative regulation of macromolecule biosynthetic process GO:0010558 270 0.035
oocyte axis specification GO:0007309 108 0.035
energy derivation by oxidation of organic compounds GO:0015980 32 0.035
ovarian follicle cell development GO:0030707 248 0.035
sensory perception GO:0007600 196 0.034
post embryonic appendage morphogenesis GO:0035120 385 0.034
dorsal closure GO:0007391 79 0.034
imaginal disc derived wing morphogenesis GO:0007476 337 0.034
positive regulation of response to stimulus GO:0048584 323 0.033
regulation of neuron projection development GO:0010975 69 0.033
exocrine system development GO:0035272 162 0.033
positive regulation of nervous system development GO:0051962 69 0.033
actomyosin structure organization GO:0031032 56 0.033
positive regulation of macromolecule metabolic process GO:0010604 405 0.033
axon target recognition GO:0007412 16 0.032
macromolecule catabolic process GO:0009057 161 0.032
mesoderm development GO:0007498 78 0.032
leg disc development GO:0035218 92 0.031
negative regulation of response to stimulus GO:0048585 258 0.031
negative regulation of signal transduction GO:0009968 206 0.031
positive regulation of macromolecule biosynthetic process GO:0010557 283 0.031
regulation of cell projection organization GO:0031344 92 0.031
response to ethanol GO:0045471 59 0.031
growth GO:0040007 359 0.031
actin filament organization GO:0007015 126 0.030
positive regulation of intracellular signal transduction GO:1902533 116 0.030
ion transmembrane transport GO:0034220 122 0.030
positive regulation of multi organism process GO:0043902 40 0.030
border follicle cell migration GO:0007298 113 0.030
regulation of cell cycle GO:0051726 291 0.030
urogenital system development GO:0001655 72 0.029
pole plasm mrna localization GO:0019094 49 0.029
oocyte construction GO:0007308 112 0.029
cell division GO:0051301 248 0.029
response to organophosphorus GO:0046683 2 0.029
epithelial cell development GO:0002064 274 0.028
regulation of cellular protein metabolic process GO:0032268 243 0.028
Human Mouse Rat
renal system development GO:0072001 72 0.028
multi organism behavior GO:0051705 175 0.028
morphogenesis of follicular epithelium GO:0016333 36 0.028
mating behavior GO:0007617 106 0.028
memory GO:0007613 94 0.028
organonitrogen compound metabolic process GO:1901564 318 0.028
response to temperature stimulus GO:0009266 106 0.028
rhythmic process GO:0048511 106 0.028
negative regulation of catalytic activity GO:0043086 42 0.028
Human
multi multicellular organism process GO:0044706 123 0.028
inorganic cation transmembrane transport GO:0098662 61 0.027
negative regulation of peptide secretion GO:0002792 1 0.027
peripheral nervous system development GO:0007422 52 0.027
regulation of cellular localization GO:0060341 136 0.027
cell maturation GO:0048469 144 0.027
nitrogen compound transport GO:0071705 85 0.027
aging GO:0007568 143 0.027
negative regulation of rna biosynthetic process GO:1902679 240 0.027
ion transport GO:0006811 145 0.027
establishment of localization in cell GO:0051649 402 0.026
gastrulation GO:0007369 70 0.026
positive regulation of transcription dna templated GO:0045893 266 0.026
negative regulation of multicellular organismal process GO:0051241 142 0.026
regulation of cellular amino acid metabolic process GO:0006521 0 0.026
negative regulation of cellular biosynthetic process GO:0031327 277 0.026
organic substance transport GO:0071702 257 0.026
cytoplasmic transport GO:0016482 130 0.026
body morphogenesis GO:0010171 2 0.026
nephron epithelium development GO:0072009 3 0.026
defense response GO:0006952 300 0.025
cellular potassium ion transport GO:0071804 18 0.025
regulation of phosphorylation GO:0042325 147 0.025
Human Mouse Rat
positive regulation of transcription from rna polymerase ii promoter GO:0045944 204 0.025
ethanolamine containing compound metabolic process GO:0042439 4 0.025
signal transduction by phosphorylation GO:0023014 107 0.025
l amino acid import GO:0043092 2 0.025
cell cell junction assembly GO:0007043 38 0.024
endomembrane system organization GO:0010256 119 0.024
stress activated protein kinase signaling cascade GO:0031098 55 0.024
embryo development ending in birth or egg hatching GO:0009792 152 0.024
cell death GO:0008219 279 0.024
regulation of cellular ketone metabolic process GO:0010565 3 0.024
columnar cuboidal epithelial cell development GO:0002066 249 0.024
negative regulation of sequence specific dna binding transcription factor activity GO:0043433 4 0.024
nucleobase containing small molecule metabolic process GO:0055086 174 0.024
mushroom body development GO:0016319 70 0.023
negative regulation of nitrogen compound metabolic process GO:0051172 265 0.023
anterior posterior axis specification embryo GO:0008595 103 0.023
response to other organism GO:0051707 293 0.023
rhythmic behavior GO:0007622 76 0.023
actin mediated cell contraction GO:0070252 21 0.023
oocyte anterior posterior axis specification GO:0007314 72 0.023
synapse organization GO:0050808 196 0.022
gastrulation with mouth forming first GO:0001703 36 0.022
response to glucose GO:0009749 2 0.022
chemical homeostasis GO:0048878 92 0.022
mapk cascade GO:0000165 107 0.022
circadian rhythm GO:0007623 105 0.022
regulation of mapk cascade GO:0043408 92 0.022
single organism catabolic process GO:0044712 228 0.022
glycoprotein biosynthetic process GO:0009101 41 0.022
positive regulation of nucleobase containing compound metabolic process GO:0045935 332 0.022
positive regulation of secretion GO:0051047 22 0.022
cellular nitrogen compound catabolic process GO:0044270 165 0.021
embryonic morphogenesis GO:0048598 206 0.021
kidney development GO:0001822 3 0.021
synaptic target recognition GO:0008039 45 0.021
regulation of hormone levels GO:0010817 40 0.021
negative regulation of biosynthetic process GO:0009890 277 0.021
carbohydrate derivative biosynthetic process GO:1901137 85 0.021
protein catabolic process GO:0030163 101 0.021
protein complex assembly GO:0006461 200 0.021
Rat
positive regulation of cell migration GO:0030335 2 0.021
gene silencing GO:0016458 138 0.021
response to nutrient levels GO:0031667 114 0.021
transmembrane receptor protein tyrosine kinase signaling pathway GO:0007169 116 0.021
cell adhesion GO:0007155 136 0.021
biological adhesion GO:0022610 138 0.021
organophosphate metabolic process GO:0019637 195 0.021
lateral inhibition GO:0046331 206 0.020
regulation of phosphorus metabolic process GO:0051174 210 0.020
Human Mouse Rat
intracellular transport GO:0046907 228 0.020
negative regulation of cell cycle GO:0045786 116 0.020
protein phosphorylation GO:0006468 169 0.020
Human Mouse Rat
negative regulation of insulin secretion GO:0046676 1 0.020
anterior posterior axis specification GO:0009948 109 0.020
regulation of behavior GO:0050795 75 0.020
negative regulation of signaling GO:0023057 219 0.020
peptidyl threonine phosphorylation GO:0018107 2 0.020
regulation of phosphate metabolic process GO:0019220 210 0.020
Human Mouse Rat
positive regulation of cell differentiation GO:0045597 64 0.020
regulation of cell morphogenesis involved in differentiation GO:0010769 61 0.020
regulation of cellular amine metabolic process GO:0033238 3 0.019
regulation of anatomical structure morphogenesis GO:0022603 242 0.019
intracellular mrna localization involved in anterior posterior axis specification GO:0060811 53 0.019
morphogenesis of an epithelium GO:0002009 276 0.019
regulation of intracellular signal transduction GO:1902531 236 0.019
cation transport GO:0006812 110 0.019
nucleoside phosphate metabolic process GO:0006753 162 0.019
positive regulation of neurogenesis GO:0050769 41 0.019
ras protein signal transduction GO:0007265 88 0.019
regulation of cellular component biogenesis GO:0044087 201 0.019
lipid biosynthetic process GO:0008610 46 0.019
ion homeostasis GO:0050801 55 0.019
muscle cell differentiation GO:0042692 103 0.019
canonical wnt signaling pathway GO:0060070 21 0.018
multicellular organismal reproductive behavior GO:0033057 110 0.018
embryonic axis specification GO:0000578 107 0.018
regulation of actin filament based process GO:0032970 42 0.018
cellular amine metabolic process GO:0044106 12 0.018
cellular response to nitrogen compound GO:1901699 51 0.018
male courtship behavior veined wing vibration GO:0016545 21 0.018
hemocyte migration GO:0035099 19 0.018
intracellular mrna localization GO:0008298 66 0.018
sensory organ morphogenesis GO:0090596 260 0.018
axis specification GO:0009798 167 0.018
purine containing compound metabolic process GO:0072521 155 0.017
segmentation GO:0035282 207 0.017
chromosome segregation GO:0007059 157 0.017
regulation of oocyte development GO:0060281 27 0.017
regulation of catabolic process GO:0009894 170 0.017
gland morphogenesis GO:0022612 145 0.017
chaeta development GO:0022416 97 0.017
negative regulation of homeostatic process GO:0032845 2 0.017
blastoderm segmentation GO:0007350 159 0.017
cellular homeostasis GO:0019725 80 0.017
regulation of ras protein signal transduction GO:0046578 93 0.017
skin development GO:0043588 65 0.017
positive regulation of cellular component biogenesis GO:0044089 80 0.017
nephron tubule development GO:0072080 3 0.017
response to oxygen containing compound GO:1901700 200 0.017
cell migration GO:0016477 238 0.017
cell fate determination GO:0001709 91 0.017
glycoprotein metabolic process GO:0009100 41 0.017
response to hormone GO:0009725 45 0.017
oxoacid metabolic process GO:0043436 103 0.017
Mouse
positive regulation of protein secretion GO:0050714 9 0.017
response to biotic stimulus GO:0009607 294 0.017
amide transport GO:0042886 10 0.017
olfactory behavior GO:0042048 97 0.016
endocytosis GO:0006897 310 0.016
meiotic cell cycle GO:0051321 171 0.016
multicellular organismal aging GO:0010259 140 0.016
phagocytosis GO:0006909 215 0.016
positive regulation of response to wounding GO:1903036 15 0.016
wnt signaling pathway GO:0016055 98 0.016
epithelial cell differentiation GO:0030855 322 0.016
head development GO:0060322 135 0.016
negative regulation of cellular protein metabolic process GO:0032269 85 0.016
Human
metal ion homeostasis GO:0055065 44 0.016
learning or memory GO:0007611 141 0.016
Mouse
organophosphate biosynthetic process GO:0090407 46 0.016
secretion GO:0046903 109 0.016
stress activated mapk cascade GO:0051403 52 0.016
imaginal disc derived leg morphogenesis GO:0007480 80 0.016
columnar cuboidal epithelial cell differentiation GO:0002065 256 0.016
single organism intracellular transport GO:1902582 207 0.016
male courtship behavior GO:0008049 63 0.016
glial cell migration GO:0008347 31 0.016
male mating behavior GO:0060179 70 0.016
ovarian follicle cell stalk formation GO:0030713 17 0.016
response to hexose GO:0009746 3 0.015
response to lipopolysaccharide GO:0032496 4 0.015
hemopoiesis GO:0030097 46 0.015
cranial nerve development GO:0021545 1 0.015
intracellular protein transport GO:0006886 104 0.015
regulation of mitotic cell cycle GO:0007346 190 0.015
amine metabolic process GO:0009308 12 0.015
dna templated transcriptional preinitiation complex assembly GO:0070897 20 0.015
cellular response to monosaccharide stimulus GO:0071326 2 0.015
response to monosaccharide GO:0034284 4 0.015
defense response to bacterium GO:0042742 178 0.015
eye photoreceptor cell differentiation GO:0001754 145 0.015
generation of precursor metabolites and energy GO:0006091 42 0.015
regulation of proteasomal protein catabolic process GO:0061136 39 0.015
potassium ion transport GO:0006813 20 0.015
apoptotic process GO:0006915 159 0.015
regulation of catalytic activity GO:0050790 185 0.014
Human Mouse Rat
response to organonitrogen compound GO:0010243 75 0.014
reproductive behavior GO:0019098 122 0.014
dorsal appendage formation GO:0046843 47 0.014
tripartite regional subdivision GO:0007351 103 0.014
male gamete generation GO:0048232 201 0.014
regulation of organelle organization GO:0033043 196 0.014
ovarian nurse cell to oocyte transport GO:0007300 27 0.014
regulation of multi organism process GO:0043900 131 0.014
innate immune response GO:0045087 144 0.014
meiotic nuclear division GO:0007126 151 0.014
cellular macromolecular complex assembly GO:0034622 153 0.014
courtship behavior GO:0007619 68 0.014
negative regulation of protein phosphorylation GO:0001933 17 0.014
Human
regulation of jnk cascade GO:0046328 40 0.014
cell cycle checkpoint GO:0000075 95 0.014
synaptic vesicle localization GO:0097479 53 0.014
positive regulation of cell motility GO:2000147 3 0.014
positive regulation of growth GO:0045927 75 0.014
central nervous system development GO:0007417 201 0.014
inorganic ion transmembrane transport GO:0098660 73 0.014
intracellular mrna localization involved in pattern specification process GO:0060810 56 0.014
positive regulation of cell development GO:0010720 61 0.013
negative regulation of meiotic cell cycle GO:0051447 2 0.013
oocyte microtubule cytoskeleton organization GO:0016325 35 0.013
cellular response to external stimulus GO:0071496 66 0.013
protein modification process GO:0036211 438 0.013
Human Mouse Rat
rna polymerase ii transcriptional preinitiation complex assembly GO:0051123 20 0.013
microtubule bundle formation GO:0001578 27 0.013
monovalent inorganic cation transport GO:0015672 40 0.013
peptidyl amino acid modification GO:0018193 105 0.013
cellular ketone metabolic process GO:0042180 24 0.013
heterochromatin organization GO:0070828 25 0.013
response to paraquat GO:1901562 4 0.013
organic substance catabolic process GO:1901575 308 0.013
germarium derived female germ line cyst encapsulation GO:0030708 8 0.013
ribose phosphate metabolic process GO:0019693 145 0.013
regulation of reproductive process GO:2000241 54 0.013
cellular amino acid metabolic process GO:0006520 61 0.013
neuromuscular junction development GO:0007528 149 0.013
regulation of peptide transport GO:0090087 7 0.013
histone modification GO:0016570 106 0.013
response to nitrogen compound GO:1901698 90 0.012
regulation of gene silencing GO:0060968 63 0.012
regulation of protein localization GO:0032880 76 0.012
immune system process GO:0002376 347 0.012
exocytosis GO:0006887 28 0.012
regulation of cellular component movement GO:0051270 42 0.012
cellular response to dna damage stimulus GO:0006974 223 0.012
regulation of hemocyte proliferation GO:0035206 37 0.012
regulation of cell cycle process GO:0010564 181 0.012
regulation of ion transport GO:0043269 39 0.012
positive regulation of cellular component organization GO:0051130 156 0.012
olfactory learning GO:0008355 56 0.012
negative regulation of peptide hormone secretion GO:0090278 1 0.012
regulation of peptide secretion GO:0002791 6 0.012
rna processing GO:0006396 147 0.012
purine nucleotide metabolic process GO:0006163 146 0.012
cellular response to organonitrogen compound GO:0071417 36 0.012
connective tissue development GO:0061448 3 0.012
regulation of protein metabolic process GO:0051246 256 0.012
Human Mouse Rat
centrosome organization GO:0051297 163 0.012
secretion by cell GO:0032940 101 0.012
regulation of protein catabolic process GO:0042176 55 0.012
response to external biotic stimulus GO:0043207 293 0.012
dna integrity checkpoint GO:0031570 81 0.012
synapse assembly GO:0007416 143 0.012
smoothened signaling pathway GO:0007224 49 0.012
positive regulation of secretion by cell GO:1903532 20 0.012
mrna metabolic process GO:0016071 124 0.012
eye photoreceptor cell development GO:0042462 81 0.012
cell junction assembly GO:0034329 42 0.012
cellular response to biotic stimulus GO:0071216 4 0.011
negative regulation of phosphate metabolic process GO:0045936 45 0.011
Human
cytokinesis GO:0000910 90 0.011
wing disc pattern formation GO:0035222 66 0.011
defense response to fungus GO:0050832 48 0.011
cell cell junction organization GO:0045216 55 0.011
somatic muscle development GO:0007525 66 0.011
spermatogenesis GO:0007283 200 0.011
regulation of cell division GO:0051302 72 0.011
multi organism reproductive behavior GO:0044705 121 0.011
maintenance of location GO:0051235 73 0.011
regulation of cell junction assembly GO:1901888 2 0.011
cellular ion homeostasis GO:0006873 39 0.011
salivary gland morphogenesis GO:0007435 145 0.011
negative regulation of cell cycle phase transition GO:1901988 103 0.011
oocyte microtubule cytoskeleton polarization GO:0008103 22 0.011
rna splicing via transesterification reactions with bulged adenosine as nucleophile GO:0000377 73 0.011
regulation of establishment of protein localization GO:0070201 61 0.011
determination of adult lifespan GO:0008340 137 0.011
cell proliferation GO:0008283 299 0.011
limb development GO:0060173 1 0.011
detection of external stimulus GO:0009581 66 0.011
cytoplasmic transport nurse cell to oocyte GO:0007303 12 0.011
regulation of cytoskeleton organization GO:0051493 89 0.011
negative regulation of developmental process GO:0051093 201 0.011
cellular response to endogenous stimulus GO:0071495 80 0.011
action potential GO:0001508 13 0.011
golgi organization GO:0007030 66 0.011
cellular macromolecule catabolic process GO:0044265 136 0.011
chromatin modification GO:0016568 147 0.011
imaginal disc pattern formation GO:0007447 91 0.011
cell aging GO:0007569 2 0.011
signal transduction downstream of smoothened GO:0007227 5 0.011
chromatin remodeling GO:0006338 72 0.011
negative regulation of nucleobase containing compound metabolic process GO:0045934 261 0.011
septate junction assembly GO:0019991 26 0.011
developmental growth involved in morphogenesis GO:0060560 65 0.011
cellular response to starvation GO:0009267 61 0.011
compound eye photoreceptor development GO:0042051 78 0.011
negative regulation of transferase activity GO:0051348 18 0.011
Human
regulation of response to stress GO:0080134 200 0.010
developmental pigmentation GO:0048066 68 0.010
peptide transport GO:0015833 10 0.010
negative chemotaxis GO:0050919 15 0.010
striated muscle cell development GO:0055002 50 0.010
jnk cascade GO:0007254 50 0.010
negative regulation of organelle organization GO:0010639 56 0.010
pyridine containing compound metabolic process GO:0072524 3 0.010
regulation of meiosis GO:0040020 3 0.010
positive regulation of developmental growth GO:0048639 62 0.010
cytoskeleton dependent intracellular transport GO:0030705 44 0.010
cuticle development GO:0042335 86 0.010
cell cycle arrest GO:0007050 4 0.010
limb morphogenesis GO:0035108 1 0.010
detection of stimulus GO:0051606 156 0.010
lipid metabolic process GO:0006629 121 0.010
Mouse
peptidyl threonine modification GO:0018210 3 0.010
positive regulation of phosphorus metabolic process GO:0010562 139 0.010
positive regulation of glial cell proliferation GO:0060252 5 0.010
nucleocytoplasmic transport GO:0006913 72 0.010
mitotic spindle organization GO:0007052 220 0.010

Pka-R2 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in fly and predicted with the fly functional network.

Disease DO term ID Size Probability Func Analog Org
diabetes mellitus DOID:9351 0 0.098
disease of metabolism DOID:0014667 0 0.098
carbohydrate metabolism disease DOID:0050013 0 0.098
glucose metabolism disease DOID:4194 0 0.098
acquired metabolic disease DOID:0060158 0 0.098
disease of anatomical entity DOID:7 0 0.045
urinary system disease DOID:18 0 0.045
cardiovascular system disease DOID:1287 0 0.039
inherited metabolic disorder DOID:655 0 0.038
sensory system disease DOID:0050155 0 0.020
eye and adnexa disease DOID:1492 0 0.020
nervous system disease DOID:863 0 0.020
eye disease DOID:5614 0 0.020
type 2 diabetes mellitus DOID:9352 0 0.019
heart conduction disease DOID:10273 0 0.019
artery disease DOID:0050828 0 0.018
vascular disease DOID:178 0 0.018