Drosophila melanogaster

22 known processes

ea (Dmel_CG4920)

easter

(Aliases: Dmel\CG4920,SP24,EA,c-SP24,CG4920)

ea biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
dorsal ventral axis specification GO:0009950 66 0.450
zygotic determination of anterior posterior axis embryo GO:0007354 27 0.350
embryo development ending in birth or egg hatching GO:0009792 152 0.345
protein maturation GO:0051604 71 0.310
positive regulation of antifungal peptide biosynthetic process GO:0006967 5 0.274
cell division GO:0051301 248 0.274
cuticle development GO:0042335 86 0.221
embryonic development via the syncytial blastoderm GO:0001700 148 0.201
response to fungus GO:0009620 50 0.153
Fly
embryonic morphogenesis GO:0048598 206 0.150
regulation of epithelial cell proliferation GO:0050678 4 0.145
establishment of localization in cell GO:0051649 402 0.137
molting cycle chitin based cuticle GO:0007591 56 0.122
establishment of nucleus localization GO:0040023 26 0.121
morphogenesis of embryonic epithelium GO:0016331 94 0.120
axon development GO:0061564 297 0.113
establishment or maintenance of cytoskeleton polarity GO:0030952 44 0.107
oocyte axis specification GO:0007309 108 0.094
positive regulation of antifungal peptide production GO:0002804 6 0.090
toll signaling pathway GO:0008063 25 0.090
Fly
oocyte differentiation GO:0009994 145 0.088
protein processing GO:0016485 68 0.086
positive regulation of signal transduction GO:0009967 223 0.085
Fly
motor neuron axon guidance GO:0008045 58 0.084
regulation of defense response to fungus GO:1900150 6 0.083
chorion containing eggshell formation GO:0007304 105 0.081
organic hydroxy compound metabolic process GO:1901615 83 0.080
Fly
positive regulation of cell communication GO:0010647 250 0.078
Fly
embryonic axis specification GO:0000578 107 0.077
antifungal peptide biosynthetic process GO:0002783 5 0.073
response to light stimulus GO:0009416 124 0.073
response to biotic stimulus GO:0009607 294 0.072
Fly
oocyte construction GO:0007308 112 0.072
positive regulation of response to stimulus GO:0048584 323 0.071
Fly
dorsal ventral pattern formation GO:0009953 133 0.071
regulation of pole plasm oskar mrna localization GO:0007317 27 0.067
defense response to bacterium GO:0042742 178 0.066
Fly
molting cycle GO:0042303 56 0.065
antifungal humoral response GO:0019732 12 0.065
negative regulation of cell communication GO:0010648 223 0.063
regulation of antifungal peptide production GO:0002788 6 0.062
regulation of antifungal peptide biosynthetic process GO:0002810 5 0.062
establishment of organelle localization GO:0051656 122 0.057
innate immune response GO:0045087 144 0.055
Fly
positive regulation of signaling GO:0023056 243 0.054
Fly
small molecule metabolic process GO:0044281 305 0.053
determination of dorsal ventral asymmetry GO:0048262 3 0.052
terminal region determination GO:0007362 25 0.052
mitotic nuclear division GO:0007067 213 0.051
columnar cuboidal epithelial cell development GO:0002066 249 0.051
positive regulation of transcription dna templated GO:0045893 266 0.049
positive regulation of rna biosynthetic process GO:1902680 266 0.049
axis specification GO:0009798 167 0.048
transcription from rna polymerase ii promoter GO:0006366 368 0.047
chemotaxis GO:0006935 249 0.046
response to radiation GO:0009314 155 0.046
cytokinesis GO:0000910 90 0.045
germ cell migration GO:0008354 43 0.045
negative regulation of cellular metabolic process GO:0031324 382 0.044
cellular ketone metabolic process GO:0042180 24 0.043
defense response GO:0006952 300 0.042
Fly
body morphogenesis GO:0010171 2 0.042
oocyte development GO:0048599 124 0.041
positive regulation of antimicrobial peptide production GO:0002225 28 0.041
Fly
negative regulation of cell cycle process GO:0010948 109 0.041
endodermal cell fate commitment GO:0001711 3 0.041
regionalization GO:0003002 416 0.041
mesenchymal cell differentiation GO:0048762 1 0.040
neurological system process GO:0050877 358 0.040
tripartite regional subdivision GO:0007351 103 0.040
taxis GO:0042330 304 0.040
endodermal cell differentiation GO:0035987 3 0.040
torso signaling pathway GO:0008293 21 0.039
nucleus localization GO:0051647 34 0.039
camera type eye development GO:0043010 4 0.038
positive regulation of nucleic acid templated transcription GO:1903508 266 0.038
cell cycle checkpoint GO:0000075 95 0.037
single organism intracellular transport GO:1902582 207 0.037
kidney development GO:0001822 3 0.036
positive regulation of cell migration GO:0030335 2 0.036
immune system process GO:0002376 347 0.036
Fly
regulation of protein metabolic process GO:0051246 256 0.036
chitin based embryonic cuticle biosynthetic process GO:0008362 16 0.034
eggshell chorion assembly GO:0007306 66 0.034
organic substance transport GO:0071702 257 0.034
intracellular transport GO:0046907 228 0.034
eggshell formation GO:0030703 105 0.034
immune response activating signal transduction GO:0002757 2 0.033
establishment of protein localization GO:0045184 163 0.033
antifungal peptide production GO:0002781 7 0.033
enzyme linked receptor protein signaling pathway GO:0007167 179 0.033
pole plasm rna localization GO:0007316 52 0.032
protein modification process GO:0036211 438 0.032
axonogenesis GO:0007409 290 0.032
macromolecular complex assembly GO:0065003 256 0.031
regulation of molecular function GO:0065009 217 0.031
positive regulation of gene expression GO:0010628 290 0.031
pole plasm assembly GO:0007315 61 0.031
positive regulation of macromolecule metabolic process GO:0010604 405 0.031
defense response to gram positive bacterium GO:0050830 41 0.031
Fly
chemosensory behavior GO:0007635 106 0.031
single organism biosynthetic process GO:0044711 206 0.031
positive regulation of cellular biosynthetic process GO:0031328 316 0.030
Fly
actin cytoskeleton organization GO:0030036 206 0.030
negative regulation of gene expression GO:0010629 387 0.030
mitotic cytokinesis GO:0000281 50 0.030
response to oxygen containing compound GO:1901700 200 0.030
positive regulation of macromolecule biosynthetic process GO:0010557 283 0.029
regulation of cellular localization GO:0060341 136 0.029
regulation of localization GO:0032879 275 0.029
cognition GO:0050890 141 0.029
regulation of embryonic pattern specification GO:1902875 27 0.029
response to organic substance GO:0010033 284 0.028
peripheral nervous system development GO:0007422 52 0.028
cellular protein modification process GO:0006464 438 0.028
regulation of intracellular signal transduction GO:1902531 236 0.028
oocyte microtubule cytoskeleton organization GO:0016325 35 0.027
nuclear import GO:0051170 51 0.027
regulation of cellular protein metabolic process GO:0032268 243 0.027
protein transport GO:0015031 155 0.026
positive regulation of multicellular organismal process GO:0051240 143 0.026
oxoacid metabolic process GO:0043436 103 0.026
response to organic cyclic compound GO:0014070 89 0.026
cell projection assembly GO:0030031 94 0.026
phosphorylation GO:0016310 294 0.026
dorsal closure GO:0007391 79 0.026
regulation of cellular ketone metabolic process GO:0010565 3 0.025
organonitrogen compound metabolic process GO:1901564 318 0.025
Fly
single organism nuclear import GO:1902593 51 0.025
establishment or maintenance of microtubule cytoskeleton polarity GO:0030951 41 0.025
regulation of cellular component movement GO:0051270 42 0.024
developmental maturation GO:0021700 172 0.024
regulation of hemocyte differentiation GO:0045610 22 0.024
protein localization GO:0008104 284 0.024
single organism behavior GO:0044708 391 0.024
lipid biosynthetic process GO:0008610 46 0.024
oocyte dorsal ventral axis specification GO:0007310 34 0.023
regulation of transport GO:0051049 181 0.023
positive regulation of nucleobase containing compound metabolic process GO:0045935 332 0.023
ameboidal type cell migration GO:0001667 151 0.023
negative regulation of phosphorus metabolic process GO:0010563 45 0.023
regulation of toll signaling pathway GO:0008592 17 0.023
Fly
negative regulation of epithelial cell proliferation GO:0050680 4 0.023
positive regulation of cell motility GO:2000147 3 0.023
pigment metabolic process GO:0042440 84 0.023
Fly
neuron projection guidance GO:0097485 241 0.023
response to bacterium GO:0009617 198 0.022
Fly
intracellular signal transduction GO:0035556 300 0.022
positive regulation of rna metabolic process GO:0051254 271 0.022
eye development GO:0001654 323 0.022
regulation of programmed cell death GO:0043067 152 0.022
synaptic transmission GO:0007268 288 0.022
response to external biotic stimulus GO:0043207 293 0.021
Fly
notch signaling pathway GO:0007219 120 0.021
transmembrane receptor protein tyrosine kinase signaling pathway GO:0007169 116 0.021
head involution GO:0008258 35 0.021
regulation of epithelial cell differentiation GO:0030856 4 0.021
regulation of cell development GO:0060284 215 0.020
regulation of cell death GO:0010941 173 0.020
regulation of phosphate metabolic process GO:0019220 210 0.020
anterior posterior axis specification embryo GO:0008595 103 0.020
regulation of apoptotic process GO:0042981 130 0.020
cellular response to lipopolysaccharide GO:0071222 3 0.020
organelle fission GO:0048285 340 0.020
regulation of response to stress GO:0080134 200 0.020
Fly
central nervous system development GO:0007417 201 0.020
cell motility GO:0048870 251 0.020
positive regulation of cell differentiation GO:0045597 64 0.019
digestive tract morphogenesis GO:0048546 127 0.019
response to nitrogen compound GO:1901698 90 0.019
protein targeting GO:0006605 64 0.019
blood circulation GO:0008015 26 0.019
negative regulation of molecular function GO:0044092 51 0.019
positive regulation of multi organism process GO:0043902 40 0.019
Fly
single organism catabolic process GO:0044712 228 0.019
cellular amino acid metabolic process GO:0006520 61 0.019
defense response to other organism GO:0098542 225 0.019
Fly
negative regulation of signaling GO:0023057 219 0.019
positive regulation of developmental process GO:0051094 143 0.019
macromolecule catabolic process GO:0009057 161 0.018
response to alcohol GO:0097305 95 0.018
positive regulation of biosynthetic process GO:0009891 316 0.018
Fly
organelle localization GO:0051640 148 0.018
retina development in camera type eye GO:0060041 4 0.018
cuticle pattern formation GO:0035017 27 0.018
protein localization to organelle GO:0033365 82 0.018
regulation of secretion by cell GO:1903530 39 0.018
establishment or maintenance of bipolar cell polarity GO:0061245 34 0.018
establishment or maintenance of polarity of follicular epithelium GO:0016334 26 0.017
cell migration GO:0016477 238 0.017
vesicle mediated transport GO:0016192 381 0.017
Fly
nuclear division GO:0000280 332 0.017
organic acid metabolic process GO:0006082 103 0.017
urogenital system development GO:0001655 72 0.017
aging GO:0007568 143 0.017
mitotic cell cycle phase transition GO:0044772 138 0.017
olfactory behavior GO:0042048 97 0.016
regulation of protein transport GO:0051223 57 0.016
larval development GO:0002164 104 0.016
lipid metabolic process GO:0006629 121 0.016
regulation of neurotransmitter levels GO:0001505 38 0.016
positive regulation of cellular component biogenesis GO:0044089 80 0.016
epithelial cell development GO:0002064 274 0.016
oocyte microtubule cytoskeleton polarization GO:0008103 22 0.016
purine nucleoside triphosphate metabolic process GO:0009144 119 0.016
epithelial cell migration GO:0010631 148 0.016
fat soluble vitamin biosynthetic process GO:0042362 1 0.015
regulation of cell division GO:0051302 72 0.015
ketone biosynthetic process GO:0042181 16 0.015
single organism cellular localization GO:1902580 180 0.015
gastrulation GO:0007369 70 0.015
ribonucleoside metabolic process GO:0009119 127 0.015
intracellular protein transport GO:0006886 104 0.015
negative regulation of autophagy GO:0010507 16 0.015
response to lipopolysaccharide GO:0032496 4 0.015
positive regulation of developmental growth GO:0048639 62 0.015
positive regulation of cellular amide metabolic process GO:0034250 26 0.015
Fly
microtubule anchoring GO:0034453 11 0.015
cell cycle phase transition GO:0044770 140 0.015
positive regulation of immune effector process GO:0002699 28 0.015
Fly
regulation of secretion GO:0051046 44 0.015
ovarian follicle cell migration GO:0007297 121 0.015
cellular response to organic substance GO:0071310 132 0.015
spermatogenesis GO:0007283 200 0.015
regulation of hydrolase activity GO:0051336 97 0.015
humoral immune response GO:0006959 117 0.015
Fly
negative regulation of rna metabolic process GO:0051253 251 0.015
purine ribonucleotide catabolic process GO:0009154 109 0.015
instar larval development GO:0002168 55 0.014
response to endogenous stimulus GO:0009719 119 0.014
regulation of cellular amine metabolic process GO:0033238 3 0.014
chitin based cuticle development GO:0040003 49 0.014
response to organophosphorus GO:0046683 2 0.014
carboxylic acid metabolic process GO:0019752 92 0.014
negative regulation of nitrogen compound metabolic process GO:0051172 265 0.014
cellular macromolecule localization GO:0070727 220 0.014
regulation of establishment of protein localization GO:0070201 61 0.014
regulation of defense response GO:0031347 102 0.014
Fly
establishment or maintenance of cell polarity GO:0007163 167 0.014
negative regulation of cellular catabolic process GO:0031330 34 0.014
protein targeting to nucleus GO:0044744 51 0.014
negative regulation of nucleobase containing compound metabolic process GO:0045934 261 0.014
regulation of protein modification process GO:0031399 112 0.014
negative regulation of cell death GO:0060548 81 0.014
synaptic growth at neuromuscular junction GO:0051124 119 0.014
death GO:0016265 284 0.013
developmental growth GO:0048589 280 0.013
anion homeostasis GO:0055081 3 0.013
mapk cascade GO:0000165 107 0.013
hormone metabolic process GO:0042445 33 0.013
regulation of cell cycle phase transition GO:1901987 130 0.013
negative regulation of proteolysis GO:0045861 31 0.013
cytoskeleton dependent cytokinesis GO:0061640 81 0.013
organic cyclic compound catabolic process GO:1901361 168 0.013
compound eye development GO:0048749 307 0.013
cellular response to molecule of bacterial origin GO:0071219 3 0.013
male gamete generation GO:0048232 201 0.013
response to other organism GO:0051707 293 0.013
Fly
regulation of organelle organization GO:0033043 196 0.013
synapse organization GO:0050808 196 0.013
regulation of multicellular organismal development GO:2000026 414 0.013
actin filament based process GO:0030029 220 0.013
organonitrogen compound biosynthetic process GO:1901566 117 0.013
Fly
pattern recognition receptor signaling pathway GO:0002221 2 0.013
cell cell junction assembly GO:0007043 38 0.013
antimicrobial humoral response GO:0019730 99 0.013
Fly
tissue morphogenesis GO:0048729 297 0.013
negative regulation of transcription dna templated GO:0045892 237 0.012
synapse assembly GO:0007416 143 0.012
organophosphate metabolic process GO:0019637 195 0.012
establishment of protein localization to organelle GO:0072594 62 0.012
apoptotic process GO:0006915 159 0.012
regulation of protein processing GO:0070613 32 0.012
regulation of cell projection organization GO:0031344 92 0.012
regulation of phosphatase activity GO:0010921 3 0.012
organic substance catabolic process GO:1901575 308 0.012
regulation of cell differentiation GO:0045595 302 0.012
morphogenesis of an epithelium GO:0002009 276 0.012
nephron epithelium development GO:0072009 3 0.012
embryonic pattern specification GO:0009880 174 0.012
negative regulation of response to stimulus GO:0048585 258 0.012
positive regulation of cytoskeleton organization GO:0051495 21 0.012
negative regulation of signal transduction GO:0009968 206 0.012
regulation of response to nutrient levels GO:0032107 18 0.012
negative regulation of cellular macromolecule biosynthetic process GO:2000113 267 0.012
digestive system development GO:0055123 149 0.012
positive regulation of i kappab kinase nf kappab signaling GO:0043123 1 0.011
multicellular organism growth GO:0035264 46 0.011
ecdysteroid biosynthetic process GO:0045456 15 0.011
regulation of cytoskeleton organization GO:0051493 89 0.011
regulation of protein polymerization GO:0032271 28 0.011
mesenchymal cell development GO:0014031 1 0.011
smoothened signaling pathway GO:0007224 49 0.011
response to wounding GO:0009611 94 0.011
cellular amine metabolic process GO:0044106 12 0.011
regulation of i kappab kinase nf kappab signaling GO:0043122 2 0.011
cytoplasmic transport GO:0016482 130 0.011
adult behavior GO:0030534 137 0.011
renal system development GO:0072001 72 0.011
epithelium migration GO:0090132 148 0.011
regulation of rna splicing GO:0043484 69 0.011
negative regulation of apoptotic process GO:0043066 63 0.011
pole plasm mrna localization GO:0019094 49 0.011
endocytosis GO:0006897 310 0.011
Fly
muscle tissue morphogenesis GO:0060415 2 0.011
actin filament organization GO:0007015 126 0.011
anterior posterior pattern specification GO:0009952 136 0.011
regulation of cell cycle process GO:0010564 181 0.011
intracellular mrna localization involved in anterior posterior axis specification GO:0060811 53 0.010
camera type eye morphogenesis GO:0048593 2 0.010
regulation of cellular amino acid metabolic process GO:0006521 0 0.010
positive regulation of protein complex assembly GO:0031334 22 0.010
regulation of immune system process GO:0002682 176 0.010
Fly
ovarian follicle cell development GO:0030707 248 0.010
regulation of synapse structure and activity GO:0050803 128 0.010
digestive tract development GO:0048565 149 0.010
response to growth factor GO:0070848 31 0.010
regulation of phosphorylation GO:0042325 147 0.010
negative regulation of programmed cell death GO:0043069 72 0.010
neurotransmitter transport GO:0006836 37 0.010
defense response to fungus GO:0050832 48 0.010
Fly
glutamate metabolic process GO:0006536 5 0.010
protein heterooligomerization GO:0051291 4 0.010

ea disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in fly and predicted with the fly functional network.

Disease DO term ID Size Probability Func Analog Org
cancer DOID:162 0 0.027
disease of cellular proliferation DOID:14566 0 0.027
organ system cancer DOID:0050686 0 0.027
disease of anatomical entity DOID:7 0 0.013
musculoskeletal system disease DOID:17 0 0.012