Drosophila melanogaster

184 known processes

piwi (Dmel_CG6122)

CG6122 gene product from transcript CG6122-RA

(Aliases: PIWI,CG6122,Dmel\CG6122,Piwi)

piwi biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
germ line stem cell maintenance GO:0030718 50 0.988
negative regulation of gene expression GO:0010629 387 0.964
pirna metabolic process GO:0034587 10 0.948
Zebrafish Mouse
germ line stem cell division GO:0042078 25 0.939
gene silencing GO:0016458 138 0.932
regulation of transposition GO:0010528 13 0.921
negative regulation of biosynthetic process GO:0009890 277 0.914
stem cell maintenance GO:0019827 67 0.910
female germ line stem cell asymmetric division GO:0048132 14 0.904
pole plasm assembly GO:0007315 61 0.892
Fly
negative regulation of macromolecule biosynthetic process GO:0010558 270 0.883
negative regulation of gene expression epigenetic GO:0045814 77 0.873
regulation of oocyte development GO:0060281 27 0.856
Fly
dorsal appendage formation GO:0046843 47 0.819
Fly
regulation of cell differentiation GO:0045595 302 0.810
immune response GO:0006955 246 0.805
Fly
dna conformation change GO:0071103 105 0.798
Fly
oocyte maturation GO:0001556 3 0.795
Fly
epithelial cell differentiation GO:0030855 322 0.791
Fly
negative regulation of nucleobase containing compound metabolic process GO:0045934 261 0.785
regulation of gene expression epigenetic GO:0040029 128 0.768
negative regulation of cellular macromolecule biosynthetic process GO:2000113 267 0.768
germarium derived egg chamber formation GO:0007293 101 0.756
positive regulation of mrna 3 end processing GO:0031442 4 0.745
chemosensory behavior GO:0007635 106 0.745
meiotic cell cycle GO:0051321 171 0.732
Zebrafish Mouse
pole plasm oskar mrna localization GO:0045451 46 0.718
Fly
segmentation GO:0035282 207 0.708
Fly
olfactory behavior GO:0042048 97 0.683
negative regulation of cellular biosynthetic process GO:0031327 277 0.681
heterochromatin organization involved in chromatin silencing GO:0070868 9 0.678
germline stem cell asymmetric division GO:0098728 15 0.667
negative regulation of transcription dna templated GO:0045892 237 0.642
germarium derived oocyte fate determination GO:0007294 26 0.601
female germ line cyst formation GO:0048135 42 0.597
stem cell differentiation GO:0048863 117 0.597
imaginal disc derived appendage development GO:0048737 399 0.585
germarium derived female germ line cyst formation GO:0030727 42 0.557
pole plasm mrna localization GO:0019094 49 0.550
Fly
germ line cyst formation GO:0048134 44 0.529
posttranscriptional gene silencing GO:0016441 46 0.513
negative regulation of transposition GO:0010529 12 0.512
chorion containing eggshell formation GO:0007304 105 0.509
Fly
response to biotic stimulus GO:0009607 294 0.506
Fly
targeting of mrna for destruction involved in rna interference GO:0030423 4 0.494
Fly
oocyte axis specification GO:0007309 108 0.477
Fly
negative regulation of developmental process GO:0051093 201 0.465
imaginal disc derived appendage morphogenesis GO:0035114 395 0.455
meiotic cell cycle process GO:1903046 132 0.453
Mouse
appendage development GO:0048736 401 0.433
regulation of cellular component biogenesis GO:0044087 201 0.420
Zebrafish Fly
heterochromatin organization GO:0070828 25 0.393
mrna catabolic process GO:0006402 33 0.383
learning GO:0007612 75 0.378
negative regulation of dna recombination GO:0045910 2 0.375
transposition rna mediated GO:0032197 3 0.373
regulation of cellular localization GO:0060341 136 0.365
Fly
tube development GO:0035295 244 0.364
negative regulation of rna biosynthetic process GO:1902679 240 0.354
eggshell formation GO:0030703 105 0.339
Fly
regulation of pole plasm oskar mrna localization GO:0007317 27 0.336
Fly
negative regulation of cellular metabolic process GO:0031324 382 0.327
production of small rna involved in gene silencing by rna GO:0070918 15 0.322
Worm
oocyte localization involved in germarium derived egg chamber formation GO:0030720 12 0.311
morphogenesis of an epithelium GO:0002009 276 0.305
posttranscriptional regulation of gene expression GO:0010608 145 0.303
transposition GO:0032196 13 0.299
rna interference GO:0016246 27 0.297
Worm Fly
dna methylation or demethylation GO:0044728 4 0.292
Mouse
oocyte nucleus localization involved in oocyte dorsal ventral axis specification GO:0051663 12 0.286
negative regulation of rna metabolic process GO:0051253 251 0.284
regulation of reproductive process GO:2000241 54 0.281
Fly
intracellular mrna localization involved in anterior posterior axis specification GO:0060811 53 0.279
Fly
fusome organization GO:0045478 13 0.278
stem cell development GO:0048864 79 0.265
male gamete generation GO:0048232 201 0.265
cell maturation GO:0048469 144 0.264
Fly
positive regulation of nitrogen compound metabolic process GO:0051173 354 0.262
olfactory learning GO:0008355 56 0.261
spermatogenesis GO:0007283 200 0.260
appendage morphogenesis GO:0035107 397 0.257
positive regulation of biosynthetic process GO:0009891 316 0.256
Mouse
blastoderm segmentation GO:0007350 159 0.252
Fly
positive regulation of nuclear transcribed mrna poly a tail shortening GO:0060213 4 0.251
tube morphogenesis GO:0035239 191 0.250
positive regulation of nucleobase containing compound metabolic process GO:0045935 332 0.247
regulation of embryonic pattern specification GO:1902875 27 0.247
Fly
posttranscriptional gene silencing by rna GO:0035194 45 0.245
Worm Fly
cell cycle dna replication GO:0044786 23 0.245
regulation of embryonic development GO:0045995 68 0.243
Fly
regulation of cell maturation GO:1903429 27 0.243
Fly
positive regulation of mrna catabolic process GO:0061014 5 0.241
protein localization GO:0008104 284 0.235
Fly
epithelial cell development GO:0002064 274 0.231
Fly
response to other organism GO:0051707 293 0.230
Fly
negative regulation of cellular component organization GO:0051129 108 0.225
Zebrafish
pole plasm rna localization GO:0007316 52 0.221
Fly
production of sirna involved in rna interference GO:0030422 11 0.214
Worm
regulation of meiosis GO:0040020 3 0.213
Mouse
positive regulation of rna metabolic process GO:0051254 271 0.213
learning or memory GO:0007611 141 0.212
associative learning GO:0008306 65 0.208
cell division GO:0051301 248 0.204
aromatic compound catabolic process GO:0019439 166 0.203
cell proliferation GO:0008283 299 0.200
defense response to bacterium GO:0042742 178 0.197
Fly
positive regulation of cellular biosynthetic process GO:0031328 316 0.195
Mouse
dna alkylation GO:0006305 4 0.194
Mouse
neurological system process GO:0050877 358 0.194
ovarian fusome organization GO:0030723 11 0.190
regulation of cell development GO:0060284 215 0.187
Fly
post embryonic appendage morphogenesis GO:0035120 385 0.187
ribonucleoprotein complex subunit organization GO:0071826 28 0.187
Fly
negative regulation of signaling GO:0023057 219 0.180
Zebrafish
stem cell division GO:0017145 69 0.179
oocyte construction GO:0007308 112 0.165
Fly
ncrna metabolic process GO:0034660 43 0.162
Zebrafish Mouse
regulation of localization GO:0032879 275 0.160
Fly
oocyte development GO:0048599 124 0.159
Fly
positive regulation of macromolecule biosynthetic process GO:0010557 283 0.159
Mouse
columnar cuboidal epithelial cell differentiation GO:0002065 256 0.150
Fly
single organism behavior GO:0044708 391 0.147
anterior posterior axis specification GO:0009948 109 0.144
Fly
eggshell chorion assembly GO:0007306 66 0.137
Fly
embryonic pattern specification GO:0009880 174 0.135
Fly
mitotic chromosome condensation GO:0007076 22 0.133
Fly
secretion by cell GO:0032940 101 0.132
nuclear division GO:0000280 332 0.132
Zebrafish Mouse Fly
negative regulation of cell differentiation GO:0045596 143 0.131
innate immune response GO:0045087 144 0.128
Fly
immune system process GO:0002376 347 0.127
Fly
negative regulation of cell division GO:0051782 17 0.121
developmental maturation GO:0021700 172 0.117
Fly
oocyte microtubule cytoskeleton organization GO:0016325 35 0.115
dna methylation GO:0006306 4 0.113
Mouse
negative regulation of response to stimulus GO:0048585 258 0.111
Zebrafish
defense response GO:0006952 300 0.109
Worm Fly
rna catabolic process GO:0006401 37 0.108
positive regulation of cellular response to insulin stimulus GO:1900078 4 0.105
positive regulation of dna endoreduplication GO:0032877 4 0.104
tissue morphogenesis GO:0048729 297 0.103
negative regulation of translation GO:0017148 28 0.103
oocyte fate determination GO:0030716 27 0.102
positive regulation of defense response GO:0031349 59 0.101
Fly
embryonic morphogenesis GO:0048598 206 0.100
cellular response to dsrna GO:0071359 15 0.099
Worm
morphogenesis of embryonic epithelium GO:0016331 94 0.097
regulation of immune response GO:0050776 118 0.097
Fly
digestive system development GO:0055123 149 0.095
chromosome segregation GO:0007059 157 0.093
Fly
negative regulation of nitrogen compound metabolic process GO:0051172 265 0.092
axis specification GO:0009798 167 0.092
Fly
heterocycle catabolic process GO:0046700 166 0.091
regulation of transposition rna mediated GO:0010525 3 0.090
anterior posterior pattern specification GO:0009952 136 0.090
Fly
regulation of cell proliferation GO:0042127 163 0.089
positive regulation of cellular catabolic process GO:0031331 95 0.088
regulation of cell cycle process GO:0010564 181 0.087
Mouse
mrna metabolic process GO:0016071 124 0.086
maternal determination of anterior posterior axis embryo GO:0008358 74 0.085
Fly
cellular macromolecule catabolic process GO:0044265 136 0.085
enzyme linked receptor protein signaling pathway GO:0007167 179 0.085
Zebrafish
gene silencing by rna GO:0031047 57 0.084
macromolecule catabolic process GO:0009057 161 0.083
regulation of cellular protein metabolic process GO:0032268 243 0.083
Mouse
positive regulation of transcription from rna polymerase ii promoter GO:0045944 204 0.083
positive regulation of rna biosynthetic process GO:1902680 266 0.082
positive regulation of transcription dna templated GO:0045893 266 0.082
positive regulation of mrna metabolic process GO:1903313 5 0.082
dna packaging GO:0006323 91 0.082
Fly
columnar cuboidal epithelial cell development GO:0002066 249 0.081
Fly
oocyte differentiation GO:0009994 145 0.080
Fly
oxoacid metabolic process GO:0043436 103 0.080
oocyte anterior posterior axis specification GO:0007314 72 0.079
Fly
digestive tract morphogenesis GO:0048546 127 0.078
central nervous system development GO:0007417 201 0.078
regulation of meiotic cell cycle GO:0051445 9 0.078
Mouse
negative regulation of cell cycle phase transition GO:1901988 103 0.076
response to external biotic stimulus GO:0043207 293 0.074
Fly
cellular macromolecular complex assembly GO:0034622 153 0.073
Zebrafish Fly
organic cyclic compound catabolic process GO:1901361 168 0.071
cellular nitrogen compound catabolic process GO:0044270 165 0.071
regionalization GO:0003002 416 0.068
Fly
regulation of mrna 3 end processing GO:0031440 7 0.068
negative regulation of cell communication GO:0010648 223 0.068
Zebrafish
carbohydrate derivative metabolic process GO:1901135 217 0.068
nucleobase containing compound catabolic process GO:0034655 165 0.067
taxis GO:0042330 304 0.066
dorsal closure GO:0007391 79 0.066
positive regulation of mrna processing GO:0050685 4 0.066
cellular catabolic process GO:0044248 372 0.065
defense response to gram negative bacterium GO:0050829 94 0.065
Fly
organic substance transport GO:0071702 257 0.065
regulation of tube architecture open tracheal system GO:0035152 68 0.065
purine ribonucleotide metabolic process GO:0009150 145 0.064
pole plasm protein localization GO:0007318 10 0.064
Fly
single organism cellular localization GO:1902580 180 0.063
Fly
negative regulation of oskar mrna translation GO:0007319 5 0.061
intercellular transport GO:0010496 2 0.061
meiotic nuclear division GO:0007126 151 0.060
Zebrafish Mouse
nuclear transcribed mrna catabolic process deadenylation dependent decay GO:0000288 14 0.059
negative regulation of nucleic acid templated transcription GO:1903507 240 0.059
cellular protein modification process GO:0006464 438 0.059
organelle fission GO:0048285 340 0.059
Zebrafish Mouse Fly
dna metabolic process GO:0006259 227 0.058
organic substance catabolic process GO:1901575 308 0.058
regulation of transport GO:0051049 181 0.057
regulation of transmembrane receptor protein serine threonine kinase signaling pathway GO:0090092 38 0.057
Zebrafish
cellular macromolecule localization GO:0070727 220 0.056
Fly
ribonucleoside monophosphate metabolic process GO:0009161 51 0.055
nitrogen compound transport GO:0071705 85 0.055
purine nucleotide metabolic process GO:0006163 146 0.055
ovarian follicle cell development GO:0030707 248 0.054
Fly
chromatin silencing GO:0006342 76 0.054
positive regulation of macromolecule metabolic process GO:0010604 405 0.054
wing disc morphogenesis GO:0007472 344 0.053
regulation of organelle organization GO:0033043 196 0.053
Mouse
negative regulation of organelle organization GO:0010639 56 0.053
purine nucleoside metabolic process GO:0042278 127 0.053
macromolecular complex assembly GO:0065003 256 0.053
Zebrafish Fly
glycosyl compound catabolic process GO:1901658 112 0.052
heterochromatin assembly GO:0031507 13 0.052
cognition GO:0050890 141 0.052
cellular response to organic cyclic compound GO:0071407 32 0.052
Worm
regulation of transcription from rna polymerase ii promoter GO:0006357 378 0.052
actin filament organization GO:0007015 126 0.052
oocyte dorsal ventral axis specification GO:0007310 34 0.052
intracellular mrna localization GO:0008298 66 0.052
Fly
adult behavior GO:0030534 137 0.052
negative regulation of meiotic cell cycle GO:0051447 2 0.051
chromatin remodeling GO:0006338 72 0.050
response to oxygen containing compound GO:1901700 200 0.050
lipid localization GO:0010876 54 0.049
sex differentiation GO:0007548 81 0.049
compound eye morphogenesis GO:0001745 249 0.049
regulation of multi organism process GO:0043900 131 0.049
Fly
lipid storage GO:0019915 38 0.048
embryonic axis specification GO:0000578 107 0.048
Fly
cell fate specification GO:0001708 71 0.048
ribonucleotide metabolic process GO:0009259 145 0.048
regulation of multicellular organismal development GO:2000026 414 0.046
Fly
regulation of defense response GO:0031347 102 0.046
Fly
chromosome organization GO:0051276 360 0.046
axon development GO:0061564 297 0.045
nucleoside triphosphate catabolic process GO:0009143 108 0.045
neural precursor cell proliferation GO:0061351 75 0.045
regulation of nuclear transcribed mrna poly a tail shortening GO:0060211 4 0.045
muscle cell differentiation GO:0042692 103 0.045
tripartite regional subdivision GO:0007351 103 0.045
Fly
regulation of translation GO:0006417 56 0.044
Mouse
regulation of nuclear transcribed mrna catabolic process deadenylation dependent decay GO:1900151 4 0.044
nucleotide catabolic process GO:0009166 109 0.043
regulation of innate immune response GO:0045088 71 0.043
Fly
sensory organ morphogenesis GO:0090596 260 0.043
ribonucleoprotein complex biogenesis GO:0022613 31 0.042
Fly
sex determination GO:0007530 18 0.042
purine containing compound metabolic process GO:0072521 155 0.042
cell motility GO:0048870 251 0.042
cytoplasm organization GO:0007028 64 0.041
Fly
establishment of oocyte nucleus localization involved in oocyte dorsal ventral axis specification GO:0030722 6 0.041
ribonucleotide catabolic process GO:0009261 109 0.040
single organism biosynthetic process GO:0044711 206 0.040
actin filament based process GO:0030029 220 0.040
rna localization GO:0006403 115 0.039
Fly
apoptotic process GO:0006915 159 0.039
regulation of mrna catabolic process GO:0061013 5 0.039
dna modification GO:0006304 5 0.039
Mouse
embryo development ending in birth or egg hatching GO:0009792 152 0.039
Worm
developmental growth GO:0048589 280 0.038
establishment of localization in cell GO:0051649 402 0.038
nuclear transcribed mrna poly a tail shortening GO:0000289 12 0.038
positive regulation of gene expression GO:0010628 290 0.038
phosphorylation GO:0016310 294 0.037
germarium derived oocyte differentiation GO:0030706 29 0.037
dna endoreduplication GO:0042023 22 0.036
ribonucleoprotein complex assembly GO:0022618 23 0.036
Fly
cellular response to nitrogen compound GO:1901699 51 0.036
Worm
regulation of nuclear division GO:0051783 58 0.035
Mouse
regulation of cell division GO:0051302 72 0.035
Mouse
translation GO:0006412 69 0.035
Mouse
defense response to other organism GO:0098542 225 0.035
Fly
eye development GO:0001654 323 0.034
negative regulation of transmembrane receptor protein serine threonine kinase signaling pathway GO:0090101 18 0.033
Zebrafish
cystoblast division GO:0007282 10 0.033
epithelium migration GO:0090132 148 0.033
nuclear transcribed mrna catabolic process GO:0000956 24 0.033
humoral immune response GO:0006959 117 0.033
regulation of anatomical structure morphogenesis GO:0022603 242 0.032
maintenance of epithelial integrity open tracheal system GO:0035160 12 0.032
regulation of organ morphogenesis GO:2000027 78 0.031
chromatin assembly or disassembly GO:0006333 52 0.031
positive regulation of signal transduction GO:0009967 223 0.031
dorsal ventral pattern formation GO:0009953 133 0.031
head development GO:0060322 135 0.030
amine metabolic process GO:0009308 12 0.030
response to organic substance GO:0010033 284 0.030
Worm
digestive tract development GO:0048565 149 0.030
salivary gland morphogenesis GO:0007435 145 0.030
catabolic process GO:0009056 409 0.030
regulation of gene silencing GO:0060968 63 0.029
programmed cell death GO:0012501 257 0.029
purine nucleoside catabolic process GO:0006152 112 0.029
axonogenesis GO:0007409 290 0.029
cuticle development GO:0042335 86 0.029
dsrna fragmentation GO:0031050 15 0.028
Worm
dna dependent dna replication GO:0006261 17 0.028
response to bacterium GO:0009617 198 0.028
Fly
positive regulation of translation GO:0045727 12 0.028
Mouse
purine nucleoside monophosphate metabolic process GO:0009126 50 0.028
regulation of dna recombination GO:0000018 4 0.027
negative regulation of dna metabolic process GO:0051053 12 0.027
nucleotide metabolic process GO:0009117 161 0.027
regulation of cell cycle GO:0051726 291 0.027
Mouse
organophosphate metabolic process GO:0019637 195 0.027
regulation of immune system process GO:0002682 176 0.026
Fly
salivary gland development GO:0007431 162 0.026
regulation of cellular catabolic process GO:0031329 157 0.026
retina development in camera type eye GO:0060041 4 0.026
mitotic sister chromatid segregation GO:0000070 87 0.026
Fly
protein modification process GO:0036211 438 0.026
organelle assembly GO:0070925 198 0.026
regulation of transcription by chromatin organization GO:0034401 3 0.026
establishment of protein localization GO:0045184 163 0.025
negative regulation of protein metabolic process GO:0051248 85 0.025
glycosyl compound metabolic process GO:1901657 127 0.025
pole cell formation GO:0007279 19 0.024
germarium derived female germ line cyst encapsulation GO:0030708 8 0.024
neuron remodeling GO:0016322 29 0.024
nucleoside metabolic process GO:0009116 127 0.024
gland morphogenesis GO:0022612 145 0.024
cell cell signaling involved in cell fate commitment GO:0045168 210 0.024
organonitrogen compound metabolic process GO:1901564 318 0.024
purine ribonucleoside triphosphate metabolic process GO:0009205 119 0.023
negative regulation of transcription from rna polymerase ii promoter GO:0000122 119 0.023
imaginal disc derived wing morphogenesis GO:0007476 337 0.023
positive regulation of nucleic acid templated transcription GO:1903508 266 0.023
wound healing GO:0042060 75 0.023
regulation of mitotic cell cycle GO:0007346 190 0.023
cellular response to chemical stimulus GO:0070887 199 0.023
Worm
epithelial tube morphogenesis GO:0060562 88 0.023
pigmentation GO:0043473 75 0.022
female germ line stem cell maintenance GO:0036099 8 0.022
ribonucleoside catabolic process GO:0042454 112 0.022
aggressive behavior GO:0002118 63 0.022
camera type eye development GO:0043010 4 0.022
modification dependent protein catabolic process GO:0019941 78 0.022
compound eye photoreceptor cell differentiation GO:0001751 140 0.022
karyosome formation GO:0030717 22 0.022
epithelial cell migration open tracheal system GO:0007427 32 0.022
photoreceptor cell differentiation GO:0046530 170 0.022
pole cell development GO:0007277 26 0.021
cellular component assembly involved in morphogenesis GO:0010927 151 0.021
Fly
positive regulation of immune response GO:0050778 63 0.021
Fly
positive regulation of response to stimulus GO:0048584 323 0.021
Fly
cellular amine metabolic process GO:0044106 12 0.021
positive regulation of signaling GO:0023056 243 0.021
cell death GO:0008219 279 0.021
homeostatic process GO:0042592 199 0.021
negative regulation of sequence specific dna binding transcription factor activity GO:0043433 4 0.021
small rna loading onto risc GO:0070922 6 0.021
regulation of cellular amine metabolic process GO:0033238 3 0.021
photoreceptor cell development GO:0042461 96 0.021
chromosome condensation GO:0030261 41 0.021
Fly
negative regulation of cell cycle GO:0045786 116 0.020
regulation of nervous system development GO:0051960 248 0.020
negative regulation of protein depolymerization GO:1901880 23 0.020
regulation of dna metabolic process GO:0051052 34 0.020
nucleoside phosphate metabolic process GO:0006753 162 0.020
positive regulation of nuclear transcribed mrna catabolic process deadenylation dependent decay GO:1900153 4 0.020
cellular ketone metabolic process GO:0042180 24 0.020
regulation of phosphate metabolic process GO:0019220 210 0.020
ribose phosphate metabolic process GO:0019693 145 0.020
positive regulation of immune system process GO:0002684 68 0.020
Fly
hindgut development GO:0061525 58 0.020
positive regulation of cell cycle process GO:0090068 28 0.019
Mouse
eye photoreceptor cell development GO:0042462 81 0.019
carboxylic acid metabolic process GO:0019752 92 0.019
negative regulation of cellular protein metabolic process GO:0032269 85 0.019
rna splicing GO:0008380 83 0.019
ribonucleoside triphosphate catabolic process GO:0009203 108 0.019
death GO:0016265 284 0.019
negative regulation of signal transduction GO:0009968 206 0.019
Zebrafish
long term memory GO:0007616 62 0.019
meiosis i GO:0007127 59 0.019
Mouse
imaginal disc derived wing vein specification GO:0007474 48 0.018
positive regulation of catalytic activity GO:0043085 118 0.018
nucleoside triphosphate metabolic process GO:0009141 120 0.018
negative regulation of multicellular organismal process GO:0051241 142 0.018
regulation of lipid transport GO:0032368 3 0.018
regulation of epidermal growth factor receptor signaling pathway GO:0042058 42 0.018
negative regulation of photoreceptor cell differentiation GO:0046533 8 0.018
compound eye photoreceptor development GO:0042051 78 0.018
regulation of imaginal disc derived wing size GO:0044719 20 0.018
imaginal disc pattern formation GO:0007447 91 0.018
rna processing GO:0006396 147 0.018
organic acid metabolic process GO:0006082 103 0.017
small molecule metabolic process GO:0044281 305 0.017
eye morphogenesis GO:0048592 260 0.017
transmembrane transport GO:0055085 139 0.017
respiratory system development GO:0060541 213 0.017
atp catabolic process GO:0006200 38 0.017
embryonic development via the syncytial blastoderm GO:0001700 148 0.017
mitotic nuclear division GO:0007067 213 0.017
Fly
actin cytoskeleton organization GO:0030036 206 0.017
positive regulation of innate immune response GO:0045089 38 0.017
Fly
response to dsrna GO:0043331 15 0.017
Worm
morphogenesis of follicular epithelium GO:0016333 36 0.017
transmembrane receptor protein serine threonine kinase signaling pathway GO:0007178 65 0.017
Zebrafish
cellular amino acid metabolic process GO:0006520 61 0.017
dendrite development GO:0016358 204 0.016
response to radiation GO:0009314 155 0.016
positive regulation of phosphorus metabolic process GO:0010562 139 0.016
striated muscle cell differentiation GO:0051146 90 0.016
inter male aggressive behavior GO:0002121 60 0.016
regulation of ras protein signal transduction GO:0046578 93 0.016
single organism intracellular transport GO:1902582 207 0.016
nucleobase containing small molecule metabolic process GO:0055086 174 0.016
compound eye development GO:0048749 307 0.016
antimicrobial humoral response GO:0019730 99 0.015
chromatin organization GO:0006325 207 0.015
brain development GO:0007420 120 0.015
purine containing compound catabolic process GO:0072523 112 0.015
egg coat formation GO:0035803 11 0.015
protein complex biogenesis GO:0070271 201 0.015
Zebrafish
regulation of anatomical structure size GO:0090066 163 0.015
renal tubule morphogenesis GO:0061333 44 0.015
rhythmic process GO:0048511 106 0.015
eye photoreceptor cell differentiation GO:0001754 145 0.015
regulation of synapse organization GO:0050807 110 0.015
regulation of developmental growth GO:0048638 174 0.014
purine nucleoside monophosphate catabolic process GO:0009128 38 0.014
nucleoside catabolic process GO:0009164 112 0.014
cellular protein localization GO:0034613 160 0.014
muscle cell development GO:0055001 50 0.014
positive regulation of histone acetylation GO:0035066 3 0.014
cellular response to organic substance GO:0071310 132 0.014
Worm
hindbrain development GO:0030902 2 0.014
polarity specification of dorsal ventral axis GO:0009951 6 0.014
positive regulation of cellular protein metabolic process GO:0032270 118 0.014
Mouse
purine ribonucleoside triphosphate catabolic process GO:0009207 108 0.013
eggshell chorion gene amplification GO:0007307 9 0.013
regulation of cellular amino acid metabolic process GO:0006521 0 0.013
reproductive system development GO:0061458 74 0.013
signal release GO:0023061 49 0.013
single organism catabolic process GO:0044712 228 0.013
intracellular signal transduction GO:0035556 300 0.013
regulation of protein complex disassembly GO:0043244 29 0.013
response to organophosphorus GO:0046683 2 0.013
regulation of cellular protein catabolic process GO:1903362 44 0.013
protein catabolic process GO:0030163 101 0.013
gene silencing by mirna GO:0035195 22 0.013
asymmetric cell division GO:0008356 37 0.013
cellularization GO:0007349 90 0.013
spermatid differentiation GO:0048515 114 0.013
Mouse
negative regulation of cell fate specification GO:0009996 15 0.013
negative regulation of cell death GO:0060548 81 0.013
synaptic transmission GO:0007268 288 0.012
mushroom body development GO:0016319 70 0.012
regulation of erbb signaling pathway GO:1901184 42 0.012
regulation of oskar mrna translation GO:0046011 8 0.012
purine nucleotide catabolic process GO:0006195 109 0.012
regulation of cell cycle phase transition GO:1901987 130 0.012
gonad development GO:0008406 50 0.012
gastrulation with mouth forming first GO:0001703 36 0.012
regulation of developmental pigmentation GO:0048070 24 0.012
maintenance of location GO:0051235 73 0.012
regulation of protein metabolic process GO:0051246 256 0.012
Mouse
oocyte microtubule cytoskeleton polarization GO:0008103 22 0.012
circulatory system process GO:0003013 37 0.012
nephron epithelium morphogenesis GO:0072088 3 0.012
regulation of secretion by cell GO:1903530 39 0.012
regulation of protein localization GO:0032880 76 0.012
nuclear transport GO:0051169 72 0.012
branching involved in open tracheal system development GO:0060446 45 0.012
phagocytosis GO:0006909 215 0.012
regulation of cell death GO:0010941 173 0.012
dorsal ventral axis specification ovarian follicular epithelium GO:0008069 13 0.012
regulation of establishment of protein localization GO:0070201 61 0.012
ovarian follicle cell stalk formation GO:0030713 17 0.011
tissue migration GO:0090130 155 0.011
nucleobase containing compound transport GO:0015931 56 0.011
regulation of dna dependent dna replication GO:0090329 6 0.011
negative regulation of cell cycle process GO:0010948 109 0.011
genital disc development GO:0035215 44 0.011
female genitalia development GO:0030540 6 0.011
regulation of cholesterol transport GO:0032374 1 0.011
organonitrogen compound catabolic process GO:1901565 128 0.011
positive regulation of nucleotide metabolic process GO:0045981 55 0.011
regulation of protein secretion GO:0050708 13 0.011
protein secretion GO:0009306 45 0.011

piwi disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in fly and predicted with the fly functional network.

Disease DO term ID Size Probability Func Analog Org
hypertension DOID:10763 0 0.060
artery disease DOID:0050828 0 0.060
disease of anatomical entity DOID:7 0 0.060
vascular disease DOID:178 0 0.060
cardiovascular system disease DOID:1287 0 0.060
essential hypertension DOID:10825 0 0.014