Drosophila melanogaster

7 known processes

CG4290 (Dmel_CG4290)

CG4290 gene product from transcript CG4290-RA

(Aliases: EG:22E5.8,Dmel\CG4290,SIK2)

CG4290 biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
homeostatic process GO:0042592 199 0.098
organonitrogen compound metabolic process GO:1901564 318 0.059
protein modification process GO:0036211 438 0.053
Mouse
phosphorylation GO:0016310 294 0.050
Mouse
regulation of response to stress GO:0080134 200 0.049
anatomical structure homeostasis GO:0060249 97 0.048
response to abiotic stimulus GO:0009628 341 0.047
Mouse
response to bacterium GO:0009617 198 0.045
cell death GO:0008219 279 0.045
Mouse
response to external biotic stimulus GO:0043207 293 0.044
cellular protein modification process GO:0006464 438 0.044
Mouse
cell proliferation GO:0008283 299 0.043
positive regulation of response to stimulus GO:0048584 323 0.042
defense response to bacterium GO:0042742 178 0.033
response to biotic stimulus GO:0009607 294 0.033
regulation of cellular amine metabolic process GO:0033238 3 0.032
regulation of mitotic cell cycle GO:0007346 190 0.032
Mouse
cellular amino acid metabolic process GO:0006520 61 0.030
localization of cell GO:0051674 257 0.030
regulation of cell proliferation GO:0042127 163 0.030
regulation of cellular component biogenesis GO:0044087 201 0.030
small molecule metabolic process GO:0044281 305 0.030
Mouse
regulation of cellular amino acid metabolic process GO:0006521 0 0.030
phagocytosis GO:0006909 215 0.029
biological adhesion GO:0022610 138 0.028
open tracheal system development GO:0007424 204 0.028
regulation of multicellular organismal development GO:2000026 414 0.028
regulation of molecular function GO:0065009 217 0.028
Mouse
regulation of anatomical structure size GO:0090066 163 0.028
positive regulation of signal transduction GO:0009967 223 0.027
regulation of immune system process GO:0002682 176 0.027
positive regulation of phosphate metabolic process GO:0045937 139 0.026
intracellular signal transduction GO:0035556 300 0.026
Mouse
regulation of immune response GO:0050776 118 0.026
defense response to other organism GO:0098542 225 0.026
sensory perception GO:0007600 196 0.026
respiratory system development GO:0060541 213 0.026
cell motility GO:0048870 251 0.026
chemical homeostasis GO:0048878 92 0.026
negative regulation of gene expression GO:0010629 387 0.026
regulation of growth GO:0040008 233 0.026
lateral inhibition GO:0046331 206 0.026
cellular catabolic process GO:0044248 372 0.025
regulation of protein metabolic process GO:0051246 256 0.025
regulation of cellular protein metabolic process GO:0032268 243 0.025
response to other organism GO:0051707 293 0.025
single organism biosynthetic process GO:0044711 206 0.025
Mouse
neurological system process GO:0050877 358 0.025
death GO:0016265 284 0.025
Mouse
multicellular organismal aging GO:0010259 140 0.025
cell adhesion GO:0007155 136 0.025
carboxylic acid metabolic process GO:0019752 92 0.024
positive regulation of cell communication GO:0010647 250 0.024
positive regulation of signaling GO:0023056 243 0.024
regulation of cell death GO:0010941 173 0.024
endocytosis GO:0006897 310 0.024
negative regulation of response to stimulus GO:0048585 258 0.024
regulation of nervous system development GO:0051960 248 0.024
peptidyl amino acid modification GO:0018193 105 0.023
immune response GO:0006955 246 0.023
programmed cell death GO:0012501 257 0.022
Mouse
negative regulation of macromolecule biosynthetic process GO:0010558 270 0.022
compound eye photoreceptor development GO:0042051 78 0.022
oxoacid metabolic process GO:0043436 103 0.022
cell recognition GO:0008037 102 0.022
cellular ketone metabolic process GO:0042180 24 0.022
Mouse
triglyceride biosynthetic process GO:0019432 2 0.022
Mouse
post embryonic appendage morphogenesis GO:0035120 385 0.022
positive regulation of nucleobase containing compound metabolic process GO:0045935 332 0.022
telencephalon development GO:0021537 2 0.022
negative regulation of cellular biosynthetic process GO:0031327 277 0.021
Mouse
cellular amine metabolic process GO:0044106 12 0.021
connective tissue development GO:0061448 3 0.021
positive regulation of rna biosynthetic process GO:1902680 266 0.021
vesicle mediated transport GO:0016192 381 0.021
regulation of defense response GO:0031347 102 0.021
imaginal disc derived wing morphogenesis GO:0007476 337 0.021
response to oxidative stress GO:0006979 86 0.021
response to oxygen containing compound GO:1901700 200 0.021
organelle assembly GO:0070925 198 0.021
compound eye morphogenesis GO:0001745 249 0.021
response to extracellular stimulus GO:0009991 116 0.021
defense response GO:0006952 300 0.021
response to glucose GO:0009749 2 0.021
response to nutrient levels GO:0031667 114 0.021
carbohydrate derivative metabolic process GO:1901135 217 0.021
organic substance catabolic process GO:1901575 308 0.021
regulation of phosphorus metabolic process GO:0051174 210 0.020
aging GO:0007568 143 0.020
eye morphogenesis GO:0048592 260 0.020
transcription from rna polymerase ii promoter GO:0006366 368 0.020
taxis GO:0042330 304 0.020
negative regulation of nitrogen compound metabolic process GO:0051172 265 0.020
response to radiation GO:0009314 155 0.020
Mouse
single organism catabolic process GO:0044712 228 0.020
axon guidance GO:0007411 233 0.020
glycosyl compound metabolic process GO:1901657 127 0.020
imaginal disc derived appendage development GO:0048737 399 0.019
ribonucleotide metabolic process GO:0009259 145 0.019
regulation of cellular ketone metabolic process GO:0010565 3 0.019
Mouse
camera type eye development GO:0043010 4 0.019
chemotaxis GO:0006935 249 0.019
forebrain development GO:0030900 2 0.019
salivary gland development GO:0007431 162 0.019
positive regulation of cell migration GO:0030335 2 0.019
ribonucleoside metabolic process GO:0009119 127 0.019
positive regulation of phosphorylation GO:0042327 87 0.019
cellular macromolecular complex assembly GO:0034622 153 0.019
negative regulation of nucleobase containing compound metabolic process GO:0045934 261 0.019
positive regulation of transcription dna templated GO:0045893 266 0.019
response to monosaccharide GO:0034284 4 0.019
cell migration GO:0016477 238 0.019
regulation of cell cycle process GO:0010564 181 0.018
response to organic substance GO:0010033 284 0.018
amine metabolic process GO:0009308 12 0.018
regulation of phosphorylation GO:0042325 147 0.018
negative regulation of rna biosynthetic process GO:1902679 240 0.018
ras protein signal transduction GO:0007265 88 0.018
regulation of catalytic activity GO:0050790 185 0.018
positive regulation of gene expression GO:0010628 290 0.018
positive regulation of multicellular organismal process GO:0051240 143 0.018
acylglycerol biosynthetic process GO:0046463 2 0.018
Mouse
cation transport GO:0006812 110 0.018
negative regulation of nucleic acid templated transcription GO:1903507 240 0.018
monovalent inorganic cation transport GO:0015672 40 0.018
nucleobase containing compound catabolic process GO:0034655 165 0.017
regionalization GO:0003002 416 0.017
nucleotide metabolic process GO:0009117 161 0.017
regulation of developmental growth GO:0048638 174 0.017
positive regulation of macromolecule metabolic process GO:0010604 405 0.017
positive regulation of phosphorus metabolic process GO:0010562 139 0.017
protein localization GO:0008104 284 0.017
appendage development GO:0048736 401 0.017
growth GO:0040007 359 0.017
exocrine system development GO:0035272 162 0.017
body morphogenesis GO:0010171 2 0.017
response to lipopolysaccharide GO:0032496 4 0.017
eye photoreceptor cell differentiation GO:0001754 145 0.017
positive regulation of cell motility GO:2000147 3 0.017
wing disc morphogenesis GO:0007472 344 0.017
cell maturation GO:0048469 144 0.016
organic cyclic compound catabolic process GO:1901361 168 0.016
morphogenesis of an epithelium GO:0002009 276 0.016
negative regulation of cellular metabolic process GO:0031324 382 0.016
Mouse
transmembrane receptor protein tyrosine kinase signaling pathway GO:0007169 116 0.016
histolysis GO:0007559 102 0.016
macromolecular complex assembly GO:0065003 256 0.016
regulation of phosphate metabolic process GO:0019220 210 0.016
eye photoreceptor cell development GO:0042462 81 0.016
adult behavior GO:0030534 137 0.016
response to organophosphorus GO:0046683 2 0.016
axon development GO:0061564 297 0.016
immune system process GO:0002376 347 0.016
sensory organ morphogenesis GO:0090596 260 0.016
regulation of cell cycle GO:0051726 291 0.016
Mouse
response to starvation GO:0042594 97 0.016
cellular component assembly involved in morphogenesis GO:0010927 151 0.016
retina development in camera type eye GO:0060041 4 0.016
negative regulation of growth GO:0045926 84 0.016
developmental maturation GO:0021700 172 0.016
regulation of intracellular signal transduction GO:1902531 236 0.016
regulation of anatomical structure morphogenesis GO:0022603 242 0.016
kidney development GO:0001822 3 0.016
cellular response to radiation GO:0071478 52 0.015
aromatic compound catabolic process GO:0019439 166 0.015
response to light stimulus GO:0009416 124 0.015
Mouse
defense response to gram negative bacterium GO:0050829 94 0.015
positive regulation of developmental process GO:0051094 143 0.015
compound eye photoreceptor cell differentiation GO:0001751 140 0.015
negative regulation of multicellular organismal process GO:0051241 142 0.015
cellular homeostasis GO:0019725 80 0.015
regulation of organelle organization GO:0033043 196 0.015
anion homeostasis GO:0055081 3 0.015
catabolic process GO:0009056 409 0.015
negative regulation of cell communication GO:0010648 223 0.015
response to hexose GO:0009746 3 0.015
nucleotide catabolic process GO:0009166 109 0.015
compound eye development GO:0048749 307 0.015
positive regulation of biosynthetic process GO:0009891 316 0.015
ion transport GO:0006811 145 0.015
protein complex biogenesis GO:0070271 201 0.015
regulation of innate immune response GO:0045088 71 0.015
tissue death GO:0016271 102 0.015
nuclear division GO:0000280 332 0.015
nucleoside metabolic process GO:0009116 127 0.015
tissue morphogenesis GO:0048729 297 0.015
positive regulation of macromolecule biosynthetic process GO:0010557 283 0.015
negative regulation of signal transduction GO:0009968 206 0.015
purine ribonucleoside metabolic process GO:0046128 127 0.015
nucleoside triphosphate catabolic process GO:0009143 108 0.014
positive regulation of molecular function GO:0044093 136 0.014
neuron projection guidance GO:0097485 241 0.014
purine ribonucleotide metabolic process GO:0009150 145 0.014
regulation of gene silencing GO:0060968 63 0.014
cell cell junction organization GO:0045216 55 0.014
positive regulation of intracellular signal transduction GO:1902533 116 0.014
single organism behavior GO:0044708 391 0.014
regulation of cellular catabolic process GO:0031329 157 0.014
mapk cascade GO:0000165 107 0.014
cell cell signaling involved in cell fate commitment GO:0045168 210 0.014
cellular nitrogen compound catabolic process GO:0044270 165 0.014
regulation of transport GO:0051049 181 0.014
regulation of localization GO:0032879 275 0.014
lipid homeostasis GO:0055088 33 0.014
regulation of programmed cell death GO:0043067 152 0.014
ribonucleoside triphosphate metabolic process GO:0009199 119 0.014
purine containing compound metabolic process GO:0072521 155 0.014
organic substance transport GO:0071702 257 0.014
nucleobase containing small molecule metabolic process GO:0055086 174 0.014
regulation of transcription from rna polymerase ii promoter GO:0006357 378 0.014
tissue homeostasis GO:0001894 36 0.014
gland morphogenesis GO:0022612 145 0.014
axonogenesis GO:0007409 290 0.014
heterocycle catabolic process GO:0046700 166 0.014
transmembrane transport GO:0055085 139 0.014
benzene containing compound metabolic process GO:0042537 3 0.014
positive regulation of nucleic acid templated transcription GO:1903508 266 0.014
salivary gland histolysis GO:0035070 88 0.013
behavioral response to ethanol GO:0048149 49 0.013
photoreceptor cell differentiation GO:0046530 170 0.013
embryonic morphogenesis GO:0048598 206 0.013
negative regulation of cellular macromolecule biosynthetic process GO:2000113 267 0.013
epithelial cell development GO:0002064 274 0.013
purine ribonucleoside triphosphate metabolic process GO:0009205 119 0.013
spindle organization GO:0007051 253 0.013
positive regulation of cellular component organization GO:0051130 156 0.013
multicellular organismal homeostasis GO:0048871 41 0.013
nucleoside triphosphate metabolic process GO:0009141 120 0.013
spermatogenesis GO:0007283 200 0.013
ribonucleotide catabolic process GO:0009261 109 0.013
nucleoside phosphate metabolic process GO:0006753 162 0.013
developmental programmed cell death GO:0010623 138 0.013
regulation of catabolic process GO:0009894 170 0.013
cellular macromolecule localization GO:0070727 220 0.013
regulation of cell substrate adhesion GO:0010810 2 0.013
activation of innate immune response GO:0002218 4 0.013
eye development GO:0001654 323 0.013
organelle fission GO:0048285 340 0.013
apoptotic process GO:0006915 159 0.013
Mouse
neuron recognition GO:0008038 101 0.013
positive regulation of catalytic activity GO:0043085 118 0.013
signal transduction by phosphorylation GO:0023014 107 0.013
sensory perception of mechanical stimulus GO:0050954 72 0.012
single organism intracellular transport GO:1902582 207 0.012
salivary gland morphogenesis GO:0007435 145 0.012
cell projection assembly GO:0030031 94 0.012
organophosphate metabolic process GO:0019637 195 0.012
adult locomotory behavior GO:0008344 76 0.012
mitotic nuclear division GO:0007067 213 0.012
innate immune response GO:0045087 144 0.012
nucleoside phosphate catabolic process GO:1901292 110 0.012
developmental growth GO:0048589 280 0.012
dorsal ventral pattern formation GO:0009953 133 0.012
response to decreased oxygen levels GO:0036293 58 0.012
mrna processing GO:0006397 104 0.012
protein complex assembly GO:0006461 200 0.012
proteolysis GO:0006508 192 0.012
purine nucleotide metabolic process GO:0006163 146 0.012
chromosome organization GO:0051276 360 0.012
detection of stimulus involved in sensory perception GO:0050906 92 0.012
neutral lipid biosynthetic process GO:0046460 2 0.012
Mouse
gland development GO:0048732 191 0.012
atp metabolic process GO:0046034 49 0.012
peptide metabolic process GO:0006518 80 0.012
enzyme linked receptor protein signaling pathway GO:0007167 179 0.012
cognition GO:0050890 141 0.012
camera type eye morphogenesis GO:0048593 2 0.012
imaginal disc derived appendage morphogenesis GO:0035114 395 0.012
positive regulation of catabolic process GO:0009896 105 0.012
positive regulation of immune system process GO:0002684 68 0.012
positive regulation of cell death GO:0010942 69 0.012
protein transport GO:0015031 155 0.012
glycosyl compound catabolic process GO:1901658 112 0.012
carbohydrate derivative catabolic process GO:1901136 118 0.012
positive regulation of transcription from rna polymerase ii promoter GO:0045944 204 0.012
regulation of protein modification process GO:0031399 112 0.012
rna processing GO:0006396 147 0.012
vitamin biosynthetic process GO:0009110 1 0.012
small gtpase mediated signal transduction GO:0007264 88 0.011
positive regulation of nervous system development GO:0051962 69 0.011
antimicrobial peptide production GO:0002775 46 0.011
photoreceptor cell development GO:0042461 96 0.011
sensory perception of chemical stimulus GO:0007606 116 0.011
regulation of apoptotic process GO:0042981 130 0.011
negative regulation of rna metabolic process GO:0051253 251 0.011
regulation of membrane potential GO:0042391 35 0.011
cation homeostasis GO:0055080 51 0.011
response to oxygen levels GO:0070482 59 0.011
ribose phosphate metabolic process GO:0019693 145 0.011
negative regulation of cell cycle GO:0045786 116 0.011
purine nucleoside catabolic process GO:0006152 112 0.011
positive regulation of nitrogen compound metabolic process GO:0051173 354 0.011
organophosphate catabolic process GO:0046434 112 0.011
lipid metabolic process GO:0006629 121 0.011
Mouse
g protein coupled receptor signaling pathway GO:0007186 136 0.011
innate immune response activating signal transduction GO:0002758 2 0.011
positive regulation of mapk cascade GO:0043410 63 0.011
nucleoside catabolic process GO:0009164 112 0.011
regulation of cell differentiation GO:0045595 302 0.011
Mouse
positive regulation of cell proliferation GO:0008284 47 0.011
organic acid metabolic process GO:0006082 103 0.011
central nervous system development GO:0007417 201 0.011
neural precursor cell proliferation GO:0061351 75 0.011
regulation of multi organism process GO:0043900 131 0.011
columnar cuboidal epithelial cell development GO:0002066 249 0.011
mrna metabolic process GO:0016071 124 0.011
appendage morphogenesis GO:0035107 397 0.011
microtubule bundle formation GO:0001578 27 0.011
ribonucleoside triphosphate catabolic process GO:0009203 108 0.011
ion transmembrane transport GO:0034220 122 0.011
positive regulation of cellular catabolic process GO:0031331 95 0.011
cellular response to dna damage stimulus GO:0006974 223 0.011
regulation of i kappab kinase nf kappab signaling GO:0043122 2 0.011
regulation of cell morphogenesis GO:0022604 163 0.011
androgen metabolic process GO:0008209 1 0.011
regulation of mapk cascade GO:0043408 92 0.011
cell cycle phase transition GO:0044770 140 0.011
regulation of small gtpase mediated signal transduction GO:0051056 93 0.011
negative regulation of cellular protein metabolic process GO:0032269 85 0.011
head development GO:0060322 135 0.011
protein phosphorylation GO:0006468 169 0.011
Mouse
eye pigment biosynthetic process GO:0006726 32 0.011
positive regulation of cellular component biogenesis GO:0044089 80 0.011
dendrite morphogenesis GO:0048813 199 0.011
cellular response to biotic stimulus GO:0071216 4 0.011
peptidyl tyrosine phosphorylation GO:0018108 24 0.011
regulation of ras protein signal transduction GO:0046578 93 0.011
positive regulation of rna metabolic process GO:0051254 271 0.011
cellular protein localization GO:0034613 160 0.011
stem cell proliferation GO:0072089 88 0.011
regulation of gene expression epigenetic GO:0040029 128 0.011
septate junction assembly GO:0019991 26 0.011
negative regulation of immune response GO:0050777 39 0.010
actin cytoskeleton organization GO:0030036 206 0.010
ribonucleoside catabolic process GO:0042454 112 0.010
response to hypoxia GO:0001666 53 0.010
intracellular protein transport GO:0006886 104 0.010
male gamete generation GO:0048232 201 0.010
regulation of proteolysis GO:0030162 87 0.010
erbb signaling pathway GO:0038127 58 0.010
acetate ester metabolic process GO:1900619 2 0.010
mesenchymal cell development GO:0014031 1 0.010
regulation of mitotic cell cycle phase transition GO:1901990 130 0.010
positive regulation of cell differentiation GO:0045597 64 0.010
vitamin metabolic process GO:0006766 2 0.010
response to copper ion GO:0046688 4 0.010
cell cell adhesion via plasma membrane adhesion molecules GO:0098742 26 0.010
cellular response to molecule of bacterial origin GO:0071219 3 0.010
cellular lipid metabolic process GO:0044255 83 0.010
Mouse
establishment of localization in cell GO:0051649 402 0.010
regulation of synaptic growth at neuromuscular junction GO:0008582 89 0.010
regulation of synapse organization GO:0050807 110 0.010
cell growth GO:0016049 108 0.010
inter male aggressive behavior GO:0002121 60 0.010
positive regulation of protein metabolic process GO:0051247 128 0.010
choline metabolic process GO:0019695 1 0.010
negative regulation of mitotic cell cycle GO:0045930 109 0.010
neuromuscular synaptic transmission GO:0007274 67 0.010
oxidation reduction process GO:0055114 123 0.010
hindbrain development GO:0030902 2 0.010
regulation of cell cycle phase transition GO:1901987 130 0.010
synapse assembly GO:0007416 143 0.010
establishment of protein localization GO:0045184 163 0.010
purine ribonucleotide catabolic process GO:0009154 109 0.010
pigment metabolic process involved in developmental pigmentation GO:0043324 33 0.010

CG4290 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in fly and predicted with the fly functional network.

Disease DO term ID Size Probability Func Analog Org
disease of anatomical entity DOID:7 0 0.059
disease of metabolism DOID:0014667 0 0.032
acquired metabolic disease DOID:0060158 0 0.032
amyloidosis DOID:9120 0 0.026
familial visceral amyloidosis DOID:0050636 0 0.026
renal tubular transport disease DOID:447 0 0.020
kidney disease DOID:557 0 0.020
urinary system disease DOID:18 0 0.020
nervous system disease DOID:863 0 0.017
inherited metabolic disorder DOID:655 0 0.015
musculoskeletal system disease DOID:17 0 0.011
cancer DOID:162 0 0.011
disease of cellular proliferation DOID:14566 0 0.011