Drosophila melanogaster

87 known processes

pelo (Dmel_CG3959)

pelota

(Aliases: Dmel\CG3959,CG3959,ms(2)01559)

pelo biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
organelle fission GO:0048285 340 0.973
meiotic cell cycle GO:0051321 171 0.969
spermatogenesis GO:0007283 200 0.935
germline stem cell asymmetric division GO:0098728 15 0.934
male gamete generation GO:0048232 201 0.931
male meiosis GO:0007140 52 0.865
negative regulation of gene expression GO:0010629 387 0.803
positive regulation of macromolecule metabolic process GO:0010604 405 0.677
meiotic cell cycle process GO:1903046 132 0.629
spermatid development GO:0007286 98 0.601
nuclear division GO:0000280 332 0.552
oocyte construction GO:0007308 112 0.493
positive regulation of nitrogen compound metabolic process GO:0051173 354 0.456
positive regulation of rna metabolic process GO:0051254 271 0.453
fusome organization GO:0045478 13 0.432
meiotic spindle organization GO:0000212 36 0.432
eye development GO:0001654 323 0.401
oocyte differentiation GO:0009994 145 0.388
oocyte development GO:0048599 124 0.387
spermatid differentiation GO:0048515 114 0.364
cellular macromolecule catabolic process GO:0044265 136 0.359
male meiosis cytokinesis GO:0007112 26 0.341
cell proliferation GO:0008283 299 0.336
Mouse
meiosis i GO:0007127 59 0.330
positive regulation of biosynthetic process GO:0009891 316 0.316
epithelial cell development GO:0002064 274 0.315
compound eye morphogenesis GO:0001745 249 0.310
mrna metabolic process GO:0016071 124 0.304
meiotic nuclear division GO:0007126 151 0.298
sensory organ morphogenesis GO:0090596 260 0.293
positive regulation of transcription from rna polymerase ii promoter GO:0045944 204 0.292
meiotic cytokinesis GO:0033206 33 0.281
positive regulation of cellular biosynthetic process GO:0031328 316 0.268
negative regulation of nitrogen compound metabolic process GO:0051172 265 0.260
regulation of cellular component biogenesis GO:0044087 201 0.243
dorsal ventral axis specification GO:0009950 66 0.242
kidney development GO:0001822 3 0.232
positive regulation of nucleobase containing compound metabolic process GO:0045935 332 0.229
germ line stem cell maintenance GO:0030718 50 0.212
mitotic nuclear division GO:0007067 213 0.204
embryo development ending in birth or egg hatching GO:0009792 152 0.193
response to organic substance GO:0010033 284 0.186
posttranscriptional regulation of gene expression GO:0010608 145 0.185
oocyte axis specification GO:0007309 108 0.163
epithelial cell differentiation GO:0030855 322 0.158
compound eye photoreceptor cell differentiation GO:0001751 140 0.155
regulation of developmental growth GO:0048638 174 0.154
eye morphogenesis GO:0048592 260 0.152
stem cell division GO:0017145 69 0.151
positive regulation of macromolecule biosynthetic process GO:0010557 283 0.149
chromosome segregation GO:0007059 157 0.142
cellular response to organic substance GO:0071310 132 0.136
ovarian fusome organization GO:0030723 11 0.134
negative regulation of cell differentiation GO:0045596 143 0.133
regulation of protein complex disassembly GO:0043244 29 0.130
oocyte dorsal ventral axis specification GO:0007310 34 0.125
stem cell maintenance GO:0019827 67 0.123
positive regulation of protein metabolic process GO:0051247 128 0.121
phosphorylation GO:0016310 294 0.115
cystoblast division GO:0007282 10 0.115
regulation of organelle organization GO:0033043 196 0.115
nucleobase containing compound catabolic process GO:0034655 165 0.113
negative regulation of developmental process GO:0051093 201 0.113
negative regulation of cellular metabolic process GO:0031324 382 0.112
multicellular organism growth GO:0035264 46 0.109
organic substance catabolic process GO:1901575 308 0.108
regulation of anatomical structure morphogenesis GO:0022603 242 0.107
positive regulation of gene expression GO:0010628 290 0.106
actin filament based process GO:0030029 220 0.104
rna processing GO:0006396 147 0.104
regulation of multicellular organismal development GO:2000026 414 0.103
regulation of cell cycle process GO:0010564 181 0.101
cellular macromolecule localization GO:0070727 220 0.101
negative regulation of macromolecule biosynthetic process GO:0010558 270 0.101
regulation of multicellular organism growth GO:0040014 40 0.098
photoreceptor cell differentiation GO:0046530 170 0.092
cellular component disassembly GO:0022411 46 0.092
cell division GO:0051301 248 0.092
reproductive system development GO:0061458 74 0.091
protein complex biogenesis GO:0070271 201 0.090
positive regulation of transcription dna templated GO:0045893 266 0.090
regulation of synaptic growth at neuromuscular junction GO:0008582 89 0.090
immune system process GO:0002376 347 0.089
axon guidance GO:0007411 233 0.088
proteolysis involved in cellular protein catabolic process GO:0051603 83 0.088
compound eye development GO:0048749 307 0.088
positive regulation of nucleic acid templated transcription GO:1903508 266 0.088
regulation of protein metabolic process GO:0051246 256 0.086
negative regulation of cellular component organization GO:0051129 108 0.086
positive regulation of cell communication GO:0010647 250 0.085
positive regulation of rna biosynthetic process GO:1902680 266 0.081
response to oxygen containing compound GO:1901700 200 0.081
negative regulation of cellular macromolecule biosynthetic process GO:2000113 267 0.081
dorsal ventral pattern formation GO:0009953 133 0.078
female germ line cyst formation GO:0048135 42 0.078
protein localization to organelle GO:0033365 82 0.078
columnar cuboidal epithelial cell differentiation GO:0002065 256 0.077
regulation of cell differentiation GO:0045595 302 0.076
synapse organization GO:0050808 196 0.076
gland development GO:0048732 191 0.074
macromolecule catabolic process GO:0009057 161 0.072
cytoskeleton dependent cytokinesis GO:0061640 81 0.070
negative regulation of phosphatase activity GO:0010923 3 0.069
negative regulation of transcription dna templated GO:0045892 237 0.065
positive regulation of developmental process GO:0051094 143 0.065
negative regulation of cell communication GO:0010648 223 0.064
transcription from rna polymerase ii promoter GO:0006366 368 0.064
negative regulation of rna metabolic process GO:0051253 251 0.063
hemopoiesis GO:0030097 46 0.061
rna interference GO:0016246 27 0.061
fertilization GO:0009566 26 0.060
germarium derived oocyte differentiation GO:0030706 29 0.060
vesicle mediated transport GO:0016192 381 0.059
cytoplasmic microtubule organization GO:0031122 22 0.059
heterocycle catabolic process GO:0046700 166 0.059
regulation of microtubule based process GO:0032886 49 0.058
ovarian follicle cell development GO:0030707 248 0.057
chromosome organization GO:0051276 360 0.055
Mouse
positive regulation of multicellular organism growth GO:0040018 21 0.055
single fertilization GO:0007338 24 0.055
catabolic process GO:0009056 409 0.053
positive regulation of catabolic process GO:0009896 105 0.053
apoptotic process GO:0006915 159 0.052
positive regulation of phosphate metabolic process GO:0045937 139 0.052
cell maturation GO:0048469 144 0.050
mitotic cell cycle checkpoint GO:0007093 88 0.050
endocytosis GO:0006897 310 0.048
reproductive structure development GO:0048608 74 0.046
carbohydrate derivative metabolic process GO:1901135 217 0.045
regulation of phosphorus metabolic process GO:0051174 210 0.044
lateral inhibition GO:0046331 206 0.044
mrna processing GO:0006397 104 0.043
organophosphate biosynthetic process GO:0090407 46 0.042
regulation of transcription from rna polymerase ii promoter GO:0006357 378 0.042
regulation of cell cycle GO:0051726 291 0.041
regulation of phosphate metabolic process GO:0019220 210 0.041
regulation of phosphorylation GO:0042325 147 0.041
small molecule metabolic process GO:0044281 305 0.041
oocyte microtubule cytoskeleton organization GO:0016325 35 0.041
regulation of cytoskeleton organization GO:0051493 89 0.040
posttranscriptional gene silencing by rna GO:0035194 45 0.040
axis specification GO:0009798 167 0.039
negative regulation of cellular biosynthetic process GO:0031327 277 0.038
cellular response to chemical stimulus GO:0070887 199 0.038
stem cell differentiation GO:0048863 117 0.038
oocyte maturation GO:0001556 3 0.037
cellular response to organic cyclic compound GO:0071407 32 0.037
regulation of response to stress GO:0080134 200 0.036
regulation of catabolic process GO:0009894 170 0.036
developmental maturation GO:0021700 172 0.036
nucleobase containing small molecule metabolic process GO:0055086 174 0.035
regulation of translation GO:0006417 56 0.035
homeostatic process GO:0042592 199 0.035
regulation of molecular function GO:0065009 217 0.034
cellular macromolecular complex assembly GO:0034622 153 0.034
negative regulation of biosynthetic process GO:0009890 277 0.034
negative regulation of signaling GO:0023057 219 0.033
female germ line stem cell asymmetric division GO:0048132 14 0.033
positive regulation of atp catabolic process GO:1903291 3 0.032
cytokinesis GO:0000910 90 0.032
mitotic cell cycle phase transition GO:0044772 138 0.032
protein phosphorylation GO:0006468 169 0.032
organonitrogen compound metabolic process GO:1901564 318 0.032
positive regulation of translation GO:0045727 12 0.032
positive regulation of signaling GO:0023056 243 0.031
immune system development GO:0002520 57 0.031
regulation of immune system process GO:0002682 176 0.031
regulation of oocyte development GO:0060281 27 0.031
germarium derived female germ line cyst formation GO:0030727 42 0.030
anatomical structure homeostasis GO:0060249 97 0.030
positive regulation of phosphorus metabolic process GO:0010562 139 0.030
spindle assembly GO:0051225 80 0.030
positive regulation of multicellular organismal process GO:0051240 143 0.030
gonad development GO:0008406 50 0.030
regulation of mitotic cell cycle GO:0007346 190 0.030
germline ring canal formation GO:0030725 13 0.029
regulation of cell shape GO:0008360 113 0.028
organophosphate metabolic process GO:0019637 195 0.028
oocyte microtubule cytoskeleton polarization GO:0008103 22 0.028
endomembrane system organization GO:0010256 119 0.028
positive regulation of cellular component organization GO:0051130 156 0.027
single organism cellular localization GO:1902580 180 0.027
regulation of gene expression epigenetic GO:0040029 128 0.027
female germ line stem cell maintenance GO:0036099 8 0.027
ribonucleoprotein complex subunit organization GO:0071826 28 0.027
protein import GO:0017038 55 0.026
positive regulation of catalytic activity GO:0043085 118 0.026
actin filament organization GO:0007015 126 0.026
establishment of protein localization to organelle GO:0072594 62 0.026
synaptic transmission GO:0007268 288 0.025
macromolecular complex disassembly GO:0032984 37 0.025
cellular nitrogen compound catabolic process GO:0044270 165 0.025
negative regulation of nucleic acid templated transcription GO:1903507 240 0.025
protein complex assembly GO:0006461 200 0.025
vesicle organization GO:0016050 44 0.024
pronuclear migration GO:0035046 4 0.024
modification dependent protein catabolic process GO:0019941 78 0.024
cellular protein complex disassembly GO:0043624 35 0.024
regulation of growth GO:0040008 233 0.024
negative regulation of nucleobase containing compound metabolic process GO:0045934 261 0.024
actin cytoskeleton organization GO:0030036 206 0.023
intracellular signal transduction GO:0035556 300 0.023
regulation of nucleocytoplasmic transport GO:0046822 35 0.023
cellular protein catabolic process GO:0044257 83 0.023
regulation of dna metabolic process GO:0051052 34 0.023
negative regulation of organelle organization GO:0010639 56 0.023
cell adhesion GO:0007155 136 0.022
protein catabolic process GO:0030163 101 0.022
microtubule depolymerization GO:0007019 25 0.022
protein import into nucleus GO:0006606 51 0.022
positive regulation of response to stimulus GO:0048584 323 0.021
cellular catabolic process GO:0044248 372 0.021
development of primary sexual characteristics GO:0045137 50 0.021
protein modification process GO:0036211 438 0.021
regulation of protein kinase activity GO:0045859 51 0.021
negative regulation of mitotic cell cycle GO:0045930 109 0.021
positive regulation of organelle organization GO:0010638 65 0.021
positive regulation of signal transduction GO:0009967 223 0.021
positive regulation of cellular protein metabolic process GO:0032270 118 0.021
protein complex disassembly GO:0043241 36 0.021
eye photoreceptor cell differentiation GO:0001754 145 0.021
photoreceptor cell development GO:0042461 96 0.020
cell cycle phase transition GO:0044770 140 0.020
negative regulation of rna biosynthetic process GO:1902679 240 0.019
regulation of transport GO:0051049 181 0.019
spindle organization GO:0007051 253 0.019
single organism biosynthetic process GO:0044711 206 0.019
programmed cell death GO:0012501 257 0.018
positive regulation of growth GO:0045927 75 0.018
cell death GO:0008219 279 0.018
establishment of localization in cell GO:0051649 402 0.018
spindle assembly involved in male meiosis GO:0007053 5 0.018
regulation of establishment of protein localization GO:0070201 61 0.018
response to organic cyclic compound GO:0014070 89 0.018
compound eye photoreceptor development GO:0042051 78 0.018
ribonucleoside triphosphate metabolic process GO:0009199 119 0.018
regulation of kinase activity GO:0043549 53 0.018
segmentation GO:0035282 207 0.017
regulation of nervous system development GO:0051960 248 0.017
organic cyclic compound catabolic process GO:1901361 168 0.017
neuromuscular junction development GO:0007528 149 0.017
sister chromatid segregation GO:0000819 92 0.017
cellular protein complex assembly GO:0043623 71 0.016
purine ribonucleoside metabolic process GO:0046128 127 0.016
positive regulation of cellular catabolic process GO:0031331 95 0.016
nuclear envelope organization GO:0006998 7 0.016
protein polymerization GO:0051258 42 0.016
mitochondrion degradation GO:0000422 8 0.016
spindle stabilization GO:0043146 14 0.016
pole plasm rna localization GO:0007316 52 0.015
positive regulation of apoptotic signaling pathway GO:2001235 4 0.015
nucleotide catabolic process GO:0009166 109 0.015
ras protein signal transduction GO:0007265 88 0.015
positive regulation of immune system process GO:0002684 68 0.015
regulation of microtubule polymerization or depolymerization GO:0031110 27 0.015
regulation of protein modification process GO:0031399 112 0.015
organelle localization GO:0051640 148 0.015
asymmetric stem cell division GO:0098722 49 0.015
female gonad development GO:0008585 12 0.015
regulation of execution phase of apoptosis GO:1900117 5 0.015
negative regulation of cellular protein metabolic process GO:0032269 85 0.014
regulation of cellular catabolic process GO:0031329 157 0.014
oocyte nucleus localization involved in oocyte dorsal ventral axis specification GO:0051663 12 0.014
protein localization GO:0008104 284 0.014
gene silencing by rna GO:0031047 57 0.014
dorsal appendage formation GO:0046843 47 0.014
chaeta development GO:0022416 97 0.014
modification dependent macromolecule catabolic process GO:0043632 79 0.014
cellular response to oxygen containing compound GO:1901701 79 0.013
protein transmembrane transport GO:0071806 4 0.013
mitotic sister chromatid segregation GO:0000070 87 0.013
proteolysis GO:0006508 192 0.013
regulation of intracellular signal transduction GO:1902531 236 0.013
transmembrane transport GO:0055085 139 0.013
regulation of cell proliferation GO:0042127 163 0.013
regulation of cell cycle phase transition GO:1901987 130 0.013
negative regulation of protein metabolic process GO:0051248 85 0.013
regulation of protein complex assembly GO:0043254 42 0.013
positive regulation of immune response GO:0050778 63 0.013
response to nitrogen compound GO:1901698 90 0.013
g2 dna damage checkpoint GO:0031572 69 0.013
sex differentiation GO:0007548 81 0.013
spermatocyte division GO:0048137 13 0.012
negative regulation of cell cycle GO:0045786 116 0.012
regulation of microtubule cytoskeleton organization GO:0070507 41 0.012
response to biotic stimulus GO:0009607 294 0.012
regulation of dna recombination GO:0000018 4 0.012
urogenital system development GO:0001655 72 0.012
stem cell development GO:0048864 79 0.012
growth GO:0040007 359 0.012
meiotic cell cycle phase transition GO:0044771 4 0.012
regulation of vesicle mediated transport GO:0060627 59 0.012
morphogenesis of an epithelium GO:0002009 276 0.012
nucleus organization GO:0006997 45 0.012
negative regulation of microtubule polymerization or depolymerization GO:0031111 21 0.012
positive regulation of hydrolase activity GO:0051345 78 0.012
response to dsrna GO:0043331 15 0.012
nucleoside metabolic process GO:0009116 127 0.012
response to abiotic stimulus GO:0009628 341 0.012
blastoderm segmentation GO:0007350 159 0.011
kidney epithelium development GO:0072073 3 0.011
regulation of stress activated protein kinase signaling cascade GO:0070302 42 0.011
proteasomal protein catabolic process GO:0010498 59 0.011
response to endogenous stimulus GO:0009719 119 0.011
translation GO:0006412 69 0.011
regulation of meiosis GO:0040020 3 0.011
aging GO:0007568 143 0.011
lipid biosynthetic process GO:0008610 46 0.011
rrna processing GO:0006364 3 0.011
germarium derived egg chamber formation GO:0007293 101 0.011
regulation of cellular ketone metabolic process GO:0010565 3 0.011
regulation of protein phosphorylation GO:0001932 64 0.011
regulation of actin filament polymerization GO:0030833 25 0.011
regulation of cell morphogenesis GO:0022604 163 0.011
synaptic growth at neuromuscular junction GO:0051124 119 0.011
response to bacterium GO:0009617 198 0.011
membrane organization GO:0061024 112 0.011
ncrna metabolic process GO:0034660 43 0.011
aromatic compound catabolic process GO:0019439 166 0.010
death GO:0016265 284 0.010
positive regulation of defense response GO:0031349 59 0.010
germ line cyst formation GO:0048134 44 0.010
production of small rna involved in gene silencing by rna GO:0070918 15 0.010
regulation of mrna catabolic process GO:0061013 5 0.010
regulation of defense response GO:0031347 102 0.010
small gtpase mediated signal transduction GO:0007264 88 0.010
carbohydrate derivative biosynthetic process GO:1901137 85 0.010
negative regulation of phosphate metabolic process GO:0045936 45 0.010
posttranscriptional gene silencing GO:0016441 46 0.010
positive regulation of protein localization to nucleus GO:1900182 21 0.010
regulation of protein catabolic process GO:0042176 55 0.010
response to external biotic stimulus GO:0043207 293 0.010

pelo disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in fly and predicted with the fly functional network.

Disease DO term ID Size Probability Func Analog Org
disease of anatomical entity DOID:7 0 0.013
nervous system disease DOID:863 0 0.010