Drosophila melanogaster

29 known processes

wmd (Dmel_CG3957)

wing morphogenesis defect

(Aliases: CG3957,CG3957/wmd,pter,Dmel\CG3957)

wmd biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
positive regulation of transcription dna templated GO:0045893 266 0.336
regulation of transcription from rna polymerase ii promoter GO:0006357 378 0.281
Mouse
transcription from rna polymerase ii promoter GO:0006366 368 0.245
Mouse
negative regulation of transcription dna templated GO:0045892 237 0.236
Mouse
positive regulation of nucleobase containing compound metabolic process GO:0045935 332 0.233
protein catabolic process GO:0030163 101 0.233
protein modification process GO:0036211 438 0.220
Human
negative regulation of nitrogen compound metabolic process GO:0051172 265 0.208
Mouse
cell proliferation GO:0008283 299 0.204
Human
positive regulation of macromolecule metabolic process GO:0010604 405 0.202
regulation of protein metabolic process GO:0051246 256 0.178
Human
positive regulation of nucleic acid templated transcription GO:1903508 266 0.165
regulation of cellular protein metabolic process GO:0032268 243 0.148
Human
negative regulation of response to stimulus GO:0048585 258 0.143
Human Mouse
proteasome mediated ubiquitin dependent protein catabolic process GO:0043161 54 0.139
negative regulation of signaling GO:0023057 219 0.133
Human Mouse
negative regulation of rna biosynthetic process GO:1902679 240 0.133
Mouse
negative regulation of nucleobase containing compound metabolic process GO:0045934 261 0.121
Mouse
positive regulation of transcription from rna polymerase ii promoter GO:0045944 204 0.116
organic substance catabolic process GO:1901575 308 0.116
positive regulation of rna biosynthetic process GO:1902680 266 0.111
negative regulation of macromolecule biosynthetic process GO:0010558 270 0.109
Mouse
cellular catabolic process GO:0044248 372 0.109
positive regulation of biosynthetic process GO:0009891 316 0.108
organonitrogen compound metabolic process GO:1901564 318 0.108
negative regulation of cellular biosynthetic process GO:0031327 277 0.108
Mouse
post embryonic appendage morphogenesis GO:0035120 385 0.105
negative regulation of rna metabolic process GO:0051253 251 0.104
Mouse
cellular protein catabolic process GO:0044257 83 0.088
vesicle mediated transport GO:0016192 381 0.087
proteolysis GO:0006508 192 0.081
modification dependent protein catabolic process GO:0019941 78 0.078
positive regulation of nitrogen compound metabolic process GO:0051173 354 0.078
cellular protein modification process GO:0006464 438 0.077
Human
proteolysis involved in cellular protein catabolic process GO:0051603 83 0.076
ubiquitin dependent protein catabolic process GO:0006511 78 0.075
positive regulation of macromolecule biosynthetic process GO:0010557 283 0.074
death GO:0016265 284 0.071
positive regulation of rna metabolic process GO:0051254 271 0.071
negative regulation of signal transduction GO:0009968 206 0.071
Human Mouse
regulation of localization GO:0032879 275 0.068
Human
positive regulation of cellular biosynthetic process GO:0031328 316 0.068
positive regulation of protein metabolic process GO:0051247 128 0.066
negative regulation of cellular metabolic process GO:0031324 382 0.062
Human Mouse
modification dependent macromolecule catabolic process GO:0043632 79 0.062
response to organic substance GO:0010033 284 0.061
Human Mouse
appendage development GO:0048736 401 0.061
positive regulation of molecular function GO:0044093 136 0.060
negative regulation of cell communication GO:0010648 223 0.060
Human Mouse
endocytosis GO:0006897 310 0.059
organic substance transport GO:0071702 257 0.058
appendage morphogenesis GO:0035107 397 0.054
catabolic process GO:0009056 409 0.054
regulation of transport GO:0051049 181 0.054
negative regulation of biosynthetic process GO:0009890 277 0.054
Mouse
chromosome organization GO:0051276 360 0.054
wing disc morphogenesis GO:0007472 344 0.053
negative regulation of cellular macromolecule biosynthetic process GO:2000113 267 0.051
Mouse
macromolecule catabolic process GO:0009057 161 0.049
protein maturation GO:0051604 71 0.049
regulation of cellular catabolic process GO:0031329 157 0.048
positive regulation of programmed cell death GO:0043068 62 0.046
programmed cell death GO:0012501 257 0.046
imaginal disc derived wing morphogenesis GO:0007476 337 0.046
regulation of protein modification process GO:0031399 112 0.045
Human
regulation of phosphate metabolic process GO:0019220 210 0.045
Human
intracellular signal transduction GO:0035556 300 0.043
regulation of molecular function GO:0065009 217 0.042
cell death GO:0008219 279 0.041
imaginal disc derived appendage development GO:0048737 399 0.041
regulation of proteolysis GO:0030162 87 0.041
positive regulation of response to stimulus GO:0048584 323 0.041
negative regulation of nucleic acid templated transcription GO:1903507 240 0.039
Mouse
protein complex biogenesis GO:0070271 201 0.038
immune response GO:0006955 246 0.038
proteasomal protein catabolic process GO:0010498 59 0.038
establishment of localization in cell GO:0051649 402 0.038
small gtpase mediated signal transduction GO:0007264 88 0.038
positive regulation of gene expression GO:0010628 290 0.037
regulation of phosphorus metabolic process GO:0051174 210 0.037
Human
negative regulation of cellular protein metabolic process GO:0032269 85 0.035
Human
protein ubiquitination GO:0016567 70 0.035
regulation of catabolic process GO:0009894 170 0.034
protein processing GO:0016485 68 0.034
regulation of gene expression epigenetic GO:0040029 128 0.034
regulation of cell cycle GO:0051726 291 0.034
protein modification by small protein conjugation or removal GO:0070647 106 0.032
camera type eye development GO:0043010 4 0.032
regulation of catalytic activity GO:0050790 185 0.032
mitotic sister chromatid segregation GO:0000070 87 0.032
cytoplasmic transport GO:0016482 130 0.031
regulation of phosphorylation GO:0042325 147 0.030
Human
regulation of protein catabolic process GO:0042176 55 0.029
response to biotic stimulus GO:0009607 294 0.029
regulation of cellular localization GO:0060341 136 0.028
neuron projection guidance GO:0097485 241 0.028
cellular macromolecule catabolic process GO:0044265 136 0.028
phagocytosis GO:0006909 215 0.028
protein k48 linked ubiquitination GO:0070936 3 0.027
immune system process GO:0002376 347 0.027
protein transport GO:0015031 155 0.026
organonitrogen compound biosynthetic process GO:1901566 117 0.026
positive regulation of proteolysis GO:0045862 52 0.026
intracellular transport GO:0046907 228 0.026
protein complex assembly GO:0006461 200 0.026
cellular response to dna damage stimulus GO:0006974 223 0.026
growth GO:0040007 359 0.025
cellular amino acid metabolic process GO:0006520 61 0.025
anatomical structure homeostasis GO:0060249 97 0.025
Human
regionalization GO:0003002 416 0.024
macromolecular complex assembly GO:0065003 256 0.024
Human
positive regulation of cell death GO:0010942 69 0.023
positive regulation of endopeptidase activity GO:0010950 26 0.023
small molecule metabolic process GO:0044281 305 0.023
methylation GO:0032259 47 0.023
negative regulation of transcription from rna polymerase ii promoter GO:0000122 119 0.022
Mouse
regulation of immune system process GO:0002682 176 0.022
dna templated transcription initiation GO:0006352 25 0.022
embryo development ending in birth or egg hatching GO:0009792 152 0.022
regulation of proteasomal ubiquitin dependent protein catabolic process GO:0032434 37 0.021
regulation of response to stress GO:0080134 200 0.021
regulation of protein localization GO:0032880 76 0.021
positive regulation of signal transduction GO:0009967 223 0.021
regulation of intracellular signal transduction GO:1902531 236 0.021
positive regulation of catalytic activity GO:0043085 118 0.021
histone methylation GO:0016571 40 0.020
intracellular protein transport GO:0006886 104 0.020
phosphorylation GO:0016310 294 0.020
Human
regulation of response to external stimulus GO:0032101 115 0.020
carboxylic acid metabolic process GO:0019752 92 0.019
protein dna complex assembly GO:0065004 63 0.019
response to radiation GO:0009314 155 0.019
positive regulation of cellular component biogenesis GO:0044089 80 0.019
protein import into nucleus GO:0006606 51 0.019
regulation of programmed cell death GO:0043067 152 0.019
homeostatic process GO:0042592 199 0.019
Human
regulation of cellular amino acid metabolic process GO:0006521 0 0.018
peptidyl lysine modification GO:0018205 57 0.018
positive regulation of catabolic process GO:0009896 105 0.018
axon development GO:0061564 297 0.018
oxoacid metabolic process GO:0043436 103 0.018
negative regulation of gene expression GO:0010629 387 0.018
Mouse
positive regulation of signaling GO:0023056 243 0.017
tissue morphogenesis GO:0048729 297 0.017
imaginal disc derived appendage morphogenesis GO:0035114 395 0.017
regulation of hydrolase activity GO:0051336 97 0.017
regulation of proteasomal protein catabolic process GO:0061136 39 0.017
chromatin modification GO:0016568 147 0.017
response to oxidative stress GO:0006979 86 0.016
transcription initiation from rna polymerase ii promoter GO:0006367 25 0.016
regulation of cellular protein catabolic process GO:1903362 44 0.016
protein targeting GO:0006605 64 0.016
signal transduction by phosphorylation GO:0023014 107 0.016
protein modification by small protein conjugation GO:0032446 79 0.016
protein localization GO:0008104 284 0.015
morphogenesis of an epithelium GO:0002009 276 0.015
retina development in camera type eye GO:0060041 4 0.015
adult behavior GO:0030534 137 0.015
dna metabolic process GO:0006259 227 0.015
chromatin organization GO:0006325 207 0.015
body morphogenesis GO:0010171 2 0.015
dna methylation or demethylation GO:0044728 4 0.015
positive regulation of cellular component organization GO:0051130 156 0.015
mitotic spindle organization GO:0007052 220 0.015
rna polymerase ii transcriptional preinitiation complex assembly GO:0051123 20 0.014
organelle fission GO:0048285 340 0.014
regulation of intracellular transport GO:0032386 64 0.014
axonogenesis GO:0007409 290 0.014
regulation of cellular component biogenesis GO:0044087 201 0.014
regulation of innate immune response GO:0045088 71 0.014
purine nucleotide metabolic process GO:0006163 146 0.014
eye development GO:0001654 323 0.014
cellular amine metabolic process GO:0044106 12 0.014
positive regulation of cellular catabolic process GO:0031331 95 0.014
regulation of cellular response to stress GO:0080135 89 0.013
positive regulation of phosphate metabolic process GO:0045937 139 0.013
regulation of proteolysis involved in cellular protein catabolic process GO:1903050 44 0.013
negative regulation of intracellular signal transduction GO:1902532 57 0.013
nuclear import GO:0051170 51 0.013
activation of cysteine type endopeptidase activity involved in apoptotic process GO:0006919 16 0.013
regulation of cell proliferation GO:0042127 163 0.013
Human
cellular macromolecule localization GO:0070727 220 0.013
chromatin remodeling GO:0006338 72 0.013
epithelial tube morphogenesis GO:0060562 88 0.013
purine containing compound metabolic process GO:0072521 155 0.013
mitotic nuclear division GO:0007067 213 0.013
hematopoietic or lymphoid organ development GO:0048534 57 0.012
mitotic cell cycle phase transition GO:0044772 138 0.012
regulation of autophagy GO:0010506 62 0.012
rna processing GO:0006396 147 0.012
Human
regulation of mitotic cell cycle GO:0007346 190 0.012
amine metabolic process GO:0009308 12 0.012
dna alkylation GO:0006305 4 0.012
mapk cascade GO:0000165 107 0.012
protein localization to nucleus GO:0034504 55 0.012
nucleoside phosphate metabolic process GO:0006753 162 0.012
negative regulation of cell cycle process GO:0010948 109 0.012
dendrite development GO:0016358 204 0.011
regulation of erbb signaling pathway GO:1901184 42 0.011
cellular response to chemical stimulus GO:0070887 199 0.011
Human Mouse
respiratory system development GO:0060541 213 0.011
positive regulation of protein modification process GO:0031401 58 0.011
activation of cysteine type endopeptidase activity GO:0097202 17 0.011
connective tissue development GO:0061448 3 0.011
positive regulation of cysteine type endopeptidase activity involved in apoptotic process GO:0043280 23 0.011
carbohydrate derivative metabolic process GO:1901135 217 0.011
positive regulation of cellular protein metabolic process GO:0032270 118 0.011
nuclear transport GO:0051169 72 0.010
positive regulation of phosphorus metabolic process GO:0010562 139 0.010
positive regulation of cell communication GO:0010647 250 0.010
sensory organ morphogenesis GO:0090596 260 0.010
regulation of cell division GO:0051302 72 0.010
regulation of establishment of protein localization GO:0070201 61 0.010

wmd disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in fly and predicted with the fly functional network.

Disease DO term ID Size Probability Func Analog Org
disease of anatomical entity DOID:7 0 0.014
disease of cellular proliferation DOID:14566 0 0.010