Drosophila melanogaster

0 known processes

CG32982 (Dmel_CG32982)

CG32982 gene product from transcript CG32982-RE

(Aliases: Dmel\CG32982,CG18566,CG9584,CG9585)

CG32982 biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
organonitrogen compound metabolic process GO:1901564 318 0.063
small molecule metabolic process GO:0044281 305 0.058
vesicle mediated transport GO:0016192 381 0.056
endocytosis GO:0006897 310 0.052
catabolic process GO:0009056 409 0.052
organophosphate metabolic process GO:0019637 195 0.051
intracellular signal transduction GO:0035556 300 0.050
regionalization GO:0003002 416 0.050
regulation of localization GO:0032879 275 0.048
imaginal disc derived wing morphogenesis GO:0007476 337 0.046
response to abiotic stimulus GO:0009628 341 0.045
gland development GO:0048732 191 0.045
regulation of phosphate metabolic process GO:0019220 210 0.044
cellular protein modification process GO:0006464 438 0.043
appendage morphogenesis GO:0035107 397 0.042
response to other organism GO:0051707 293 0.042
transcription from rna polymerase ii promoter GO:0006366 368 0.041
protein modification process GO:0036211 438 0.041
phosphorylation GO:0016310 294 0.040
eye development GO:0001654 323 0.039
negative regulation of cellular metabolic process GO:0031324 382 0.038
response to organic substance GO:0010033 284 0.037
post embryonic appendage morphogenesis GO:0035120 385 0.037
regulation of transport GO:0051049 181 0.037
imaginal disc derived appendage development GO:0048737 399 0.037
appendage development GO:0048736 401 0.036
nucleotide metabolic process GO:0009117 161 0.036
positive regulation of nitrogen compound metabolic process GO:0051173 354 0.036
organic substance transport GO:0071702 257 0.036
regulation of transcription from rna polymerase ii promoter GO:0006357 378 0.036
cellular catabolic process GO:0044248 372 0.035
salivary gland development GO:0007431 162 0.035
regulation of phosphorus metabolic process GO:0051174 210 0.035
gland morphogenesis GO:0022612 145 0.035
establishment of localization in cell GO:0051649 402 0.034
regulation of response to stress GO:0080134 200 0.033
cell proliferation GO:0008283 299 0.033
negative regulation of response to stimulus GO:0048585 258 0.033
negative regulation of gene expression GO:0010629 387 0.032
positive regulation of response to stimulus GO:0048584 323 0.032
negative regulation of nitrogen compound metabolic process GO:0051172 265 0.032
compound eye morphogenesis GO:0001745 249 0.032
response to external biotic stimulus GO:0043207 293 0.031
immune system process GO:0002376 347 0.031
response to bacterium GO:0009617 198 0.031
positive regulation of macromolecule metabolic process GO:0010604 405 0.031
g protein coupled receptor signaling pathway GO:0007186 136 0.031
positive regulation of signaling GO:0023056 243 0.031
regulation of catalytic activity GO:0050790 185 0.031
negative regulation of signaling GO:0023057 219 0.030
wing disc morphogenesis GO:0007472 344 0.030
carbohydrate derivative metabolic process GO:1901135 217 0.030
synapse organization GO:0050808 196 0.030
regulation of intracellular signal transduction GO:1902531 236 0.030
axon guidance GO:0007411 233 0.030
single organism catabolic process GO:0044712 228 0.030
motor neuron axon guidance GO:0008045 58 0.030
response to biotic stimulus GO:0009607 294 0.029
exocrine system development GO:0035272 162 0.029
nucleobase containing small molecule metabolic process GO:0055086 174 0.029
organic substance catabolic process GO:1901575 308 0.028
epithelial cell differentiation GO:0030855 322 0.028
carboxylic acid metabolic process GO:0019752 92 0.028
regulation of protein metabolic process GO:0051246 256 0.028
response to lipopolysaccharide GO:0032496 4 0.028
neuron recognition GO:0008038 101 0.028
regulation of molecular function GO:0065009 217 0.028
developmental programmed cell death GO:0010623 138 0.027
sensory organ morphogenesis GO:0090596 260 0.027
cell cell signaling involved in cell fate commitment GO:0045168 210 0.027
developmental maturation GO:0021700 172 0.027
phagocytosis GO:0006909 215 0.027
positive regulation of nucleobase containing compound metabolic process GO:0045935 332 0.027
histolysis GO:0007559 102 0.027
salivary gland morphogenesis GO:0007435 145 0.027
imaginal disc derived appendage morphogenesis GO:0035114 395 0.027
lateral inhibition GO:0046331 206 0.026
cell death GO:0008219 279 0.026
programmed cell death GO:0012501 257 0.026
regulation of cellular protein metabolic process GO:0032268 243 0.026
positive regulation of signal transduction GO:0009967 223 0.026
cell motility GO:0048870 251 0.026
growth GO:0040007 359 0.026
purine nucleotide metabolic process GO:0006163 146 0.026
response to oxygen containing compound GO:1901700 200 0.026
regulation of cell differentiation GO:0045595 302 0.026
negative regulation of cell communication GO:0010648 223 0.026
homeostatic process GO:0042592 199 0.025
actin cytoskeleton organization GO:0030036 206 0.025
negative regulation of nucleobase containing compound metabolic process GO:0045934 261 0.025
organic acid metabolic process GO:0006082 103 0.025
regulation of cellular component biogenesis GO:0044087 201 0.025
tissue death GO:0016271 102 0.024
male gamete generation GO:0048232 201 0.024
connective tissue development GO:0061448 3 0.024
single organism biosynthetic process GO:0044711 206 0.024
forebrain development GO:0030900 2 0.024
eye morphogenesis GO:0048592 260 0.024
nucleoside phosphate metabolic process GO:0006753 162 0.023
chemotaxis GO:0006935 249 0.023
purine containing compound metabolic process GO:0072521 155 0.023
adult behavior GO:0030534 137 0.023
positive regulation of cellular biosynthetic process GO:0031328 316 0.023
neurological system process GO:0050877 358 0.023
localization of cell GO:0051674 257 0.023
organonitrogen compound biosynthetic process GO:1901566 117 0.023
central nervous system development GO:0007417 201 0.023
cellular response to chemical stimulus GO:0070887 199 0.023
regulation of cellular amine metabolic process GO:0033238 3 0.023
regulation of cellular amino acid metabolic process GO:0006521 0 0.023
cell recognition GO:0008037 102 0.022
regulation of cell death GO:0010941 173 0.022
regulation of cellular ketone metabolic process GO:0010565 3 0.022
purine ribonucleotide metabolic process GO:0009150 145 0.022
proteolysis GO:0006508 192 0.022
axon development GO:0061564 297 0.022
columnar cuboidal epithelial cell differentiation GO:0002065 256 0.021
embryonic pattern specification GO:0009880 174 0.021
axonogenesis GO:0007409 290 0.021
ras protein signal transduction GO:0007265 88 0.021
regulation of phosphorylation GO:0042325 147 0.021
oxoacid metabolic process GO:0043436 103 0.021
morphogenesis of an epithelium GO:0002009 276 0.021
aromatic compound catabolic process GO:0019439 166 0.021
regulation of multicellular organismal development GO:2000026 414 0.021
segmentation GO:0035282 207 0.021
positive regulation of phosphorus metabolic process GO:0010562 139 0.021
positive regulation of cell communication GO:0010647 250 0.020
regulation of nervous system development GO:0051960 248 0.020
regulation of multi organism process GO:0043900 131 0.020
synaptic transmission GO:0007268 288 0.020
ion transport GO:0006811 145 0.020
negative regulation of transcription dna templated GO:0045892 237 0.020
positive regulation of biosynthetic process GO:0009891 316 0.020
camera type eye development GO:0043010 4 0.020
death GO:0016265 284 0.020
negative regulation of nucleic acid templated transcription GO:1903507 240 0.020
regulation of cell cycle GO:0051726 291 0.020
secretion GO:0046903 109 0.020
detection of stimulus GO:0051606 156 0.020
regulation of cell proliferation GO:0042127 163 0.020
amine metabolic process GO:0009308 12 0.020
negative regulation of signal transduction GO:0009968 206 0.019
nucleobase containing compound catabolic process GO:0034655 165 0.019
kidney development GO:0001822 3 0.019
positive regulation of rna biosynthetic process GO:1902680 266 0.019
protein phosphorylation GO:0006468 169 0.019
transmembrane receptor protein tyrosine kinase signaling pathway GO:0007169 116 0.019
small gtpase mediated signal transduction GO:0007264 88 0.019
neuron projection guidance GO:0097485 241 0.019
negative regulation of multicellular organismal process GO:0051241 142 0.019
spermatogenesis GO:0007283 200 0.019
single organism behavior GO:0044708 391 0.019
purine containing compound catabolic process GO:0072523 112 0.019
ribonucleotide metabolic process GO:0009259 145 0.019
positive regulation of multicellular organismal process GO:0051240 143 0.019
embryonic development via the syncytial blastoderm GO:0001700 148 0.019
positive regulation of gene expression GO:0010628 290 0.019
organonitrogen compound catabolic process GO:1901565 128 0.019
heterocycle catabolic process GO:0046700 166 0.018
enzyme linked receptor protein signaling pathway GO:0007167 179 0.018
positive regulation of molecular function GO:0044093 136 0.018
axis specification GO:0009798 167 0.018
cellular amine metabolic process GO:0044106 12 0.018
columnar cuboidal epithelial cell development GO:0002066 249 0.018
detection of chemical stimulus GO:0009593 93 0.018
positive regulation of phosphate metabolic process GO:0045937 139 0.018
defense response GO:0006952 300 0.018
negative regulation of cellular macromolecule biosynthetic process GO:2000113 267 0.018
cholesterol homeostasis GO:0042632 3 0.018
regulation of immune system process GO:0002682 176 0.018
nuclear division GO:0000280 332 0.018
positive regulation of cell migration GO:0030335 2 0.018
organelle fission GO:0048285 340 0.018
organic cyclic compound catabolic process GO:1901361 168 0.018
sterol homeostasis GO:0055092 4 0.018
negative regulation of biosynthetic process GO:0009890 277 0.018
cellular amino acid metabolic process GO:0006520 61 0.018
regulation of synapse organization GO:0050807 110 0.017
epithelial cell development GO:0002064 274 0.017
protein localization GO:0008104 284 0.017
defense response to other organism GO:0098542 225 0.017
tube development GO:0035295 244 0.017
ribose phosphate metabolic process GO:0019693 145 0.017
peptide metabolic process GO:0006518 80 0.017
compound eye development GO:0048749 307 0.017
regulation of programmed cell death GO:0043067 152 0.017
regulation of apoptotic process GO:0042981 130 0.017
regulation of catabolic process GO:0009894 170 0.017
positive regulation of cellular protein metabolic process GO:0032270 118 0.017
dendrite development GO:0016358 204 0.017
positive regulation of nucleic acid templated transcription GO:1903508 266 0.017
positive regulation of hydrolase activity GO:0051345 78 0.017
cell migration GO:0016477 238 0.017
biological adhesion GO:0022610 138 0.017
body morphogenesis GO:0010171 2 0.017
salivary gland histolysis GO:0035070 88 0.017
taxis GO:0042330 304 0.016
positive regulation of catalytic activity GO:0043085 118 0.016
negative regulation of developmental process GO:0051093 201 0.016
cellularization GO:0007349 90 0.016
regulation of organelle organization GO:0033043 196 0.016
regulation of response to external stimulus GO:0032101 115 0.016
polyol biosynthetic process GO:0046173 3 0.016
regulation of cellular catabolic process GO:0031329 157 0.016
cellular response to organic substance GO:0071310 132 0.016
positive regulation of rna metabolic process GO:0051254 271 0.016
purine nucleoside triphosphate metabolic process GO:0009144 119 0.016
chaeta development GO:0022416 97 0.016
actin filament based process GO:0030029 220 0.016
blastoderm segmentation GO:0007350 159 0.016
nucleoside triphosphate metabolic process GO:0009141 120 0.016
positive regulation of catabolic process GO:0009896 105 0.016
regulation of immune response GO:0050776 118 0.016
positive regulation of developmental process GO:0051094 143 0.016
ethanolamine containing compound metabolic process GO:0042439 4 0.016
regulation of vesicle mediated transport GO:0060627 59 0.016
olfactory behavior GO:0042048 97 0.016
cellular nitrogen compound catabolic process GO:0044270 165 0.016
glycosyl compound catabolic process GO:1901658 112 0.016
negative regulation of cellular biosynthetic process GO:0031327 277 0.016
synaptic target recognition GO:0008039 45 0.015
chemical homeostasis GO:0048878 92 0.015
regulation of mitotic cell cycle GO:0007346 190 0.015
nucleoside catabolic process GO:0009164 112 0.015
tissue morphogenesis GO:0048729 297 0.015
cholesterol transport GO:0030301 2 0.015
organophosphate catabolic process GO:0046434 112 0.015
defense response to bacterium GO:0042742 178 0.015
intracellular transport GO:0046907 228 0.015
secretion by cell GO:0032940 101 0.015
positive regulation of intracellular signal transduction GO:1902533 116 0.015
positive regulation of protein metabolic process GO:0051247 128 0.015
ribonucleoside catabolic process GO:0042454 112 0.015
cellular amide metabolic process GO:0043603 80 0.015
response to organophosphorus GO:0046683 2 0.015
purine ribonucleoside metabolic process GO:0046128 127 0.015
regulation of hydrolase activity GO:0051336 97 0.015
nucleoside phosphate catabolic process GO:1901292 110 0.015
dendrite morphogenesis GO:0048813 199 0.015
salivary gland cell autophagic cell death GO:0035071 83 0.015
response to radiation GO:0009314 155 0.015
chromosome organization GO:0051276 360 0.015
regulation of cellular localization GO:0060341 136 0.015
embryonic morphogenesis GO:0048598 206 0.015
open tracheal system development GO:0007424 204 0.015
mapk cascade GO:0000165 107 0.015
actin filament organization GO:0007015 126 0.015
ribonucleoside triphosphate catabolic process GO:0009203 108 0.015
respiratory system development GO:0060541 213 0.015
purine ribonucleoside triphosphate metabolic process GO:0009205 119 0.015
chemosensory behavior GO:0007635 106 0.015
regulation of nucleotide metabolic process GO:0006140 62 0.015
positive regulation of peptidase activity GO:0010952 29 0.015
purine ribonucleotide catabolic process GO:0009154 109 0.014
immune system development GO:0002520 57 0.014
glycosyl compound metabolic process GO:1901657 127 0.014
regulation of cell development GO:0060284 215 0.014
gtp catabolic process GO:0006184 72 0.014
spermatid differentiation GO:0048515 114 0.014
sensory perception of chemical stimulus GO:0007606 116 0.014
compound eye photoreceptor cell differentiation GO:0001751 140 0.014
regulation of anatomical structure morphogenesis GO:0022603 242 0.014
cellular response to dna damage stimulus GO:0006974 223 0.014
head development GO:0060322 135 0.014
developmental growth GO:0048589 280 0.014
cell maturation GO:0048469 144 0.014
telencephalon development GO:0021537 2 0.014
autophagic cell death GO:0048102 83 0.014
negative regulation of rna biosynthetic process GO:1902679 240 0.014
cell adhesion GO:0007155 136 0.014
positive regulation of transcription dna templated GO:0045893 266 0.014
carbohydrate derivative catabolic process GO:1901136 118 0.014
nucleoside triphosphate catabolic process GO:0009143 108 0.014
regulation of mapk cascade GO:0043408 92 0.014
transmembrane transport GO:0055085 139 0.014
brain development GO:0007420 120 0.014
ovarian follicle cell development GO:0030707 248 0.014
nitrogen compound transport GO:0071705 85 0.014
positive regulation of cell motility GO:2000147 3 0.014
purine nucleoside metabolic process GO:0042278 127 0.014
triglyceride biosynthetic process GO:0019432 2 0.014
pigment metabolic process GO:0042440 84 0.014
nephron epithelium development GO:0072009 3 0.014
regulation of small gtpase mediated signal transduction GO:0051056 93 0.014
single organism intracellular transport GO:1902582 207 0.014
regulation of neurogenesis GO:0050767 158 0.014
ribonucleotide catabolic process GO:0009261 109 0.014
signal transduction by phosphorylation GO:0023014 107 0.013
ribonucleoside triphosphate metabolic process GO:0009199 119 0.013
spindle organization GO:0007051 253 0.013
organelle assembly GO:0070925 198 0.013
photoreceptor cell development GO:0042461 96 0.013
regulation of synapse structure and activity GO:0050803 128 0.013
antimicrobial humoral response GO:0019730 99 0.013
maintenance of location GO:0051235 73 0.013
protein modification by small protein conjugation GO:0032446 79 0.013
eye photoreceptor cell differentiation GO:0001754 145 0.013
notch signaling pathway GO:0007219 120 0.013
rna processing GO:0006396 147 0.013
nucleoside metabolic process GO:0009116 127 0.013
rna localization GO:0006403 115 0.013
immune response GO:0006955 246 0.013
kidney epithelium development GO:0072073 3 0.013
purine nucleotide catabolic process GO:0006195 109 0.013
cellular response to biotic stimulus GO:0071216 4 0.013
ameboidal type cell migration GO:0001667 151 0.013
synapse assembly GO:0007416 143 0.013
retina development in camera type eye GO:0060041 4 0.013
purine ribonucleoside catabolic process GO:0046130 112 0.013
synaptic vesicle transport GO:0048489 50 0.013
detection of stimulus involved in sensory perception GO:0050906 92 0.013
locomotory behavior GO:0007626 176 0.013
regulation of peptidase activity GO:0052547 39 0.013
regulation of purine nucleotide metabolic process GO:1900542 62 0.013
purine nucleoside catabolic process GO:0006152 112 0.013
eye photoreceptor cell development GO:0042462 81 0.013
protein transport GO:0015031 155 0.013
nucleotide catabolic process GO:0009166 109 0.013
macromolecule catabolic process GO:0009057 161 0.013
nephron development GO:0072006 3 0.013
negative regulation of macromolecule biosynthetic process GO:0010558 270 0.012
amide biosynthetic process GO:0043604 42 0.012
establishment of protein localization GO:0045184 163 0.012
adult locomotory behavior GO:0008344 76 0.012
chromosome segregation GO:0007059 157 0.012
cellular component assembly involved in morphogenesis GO:0010927 151 0.012
extrinsic apoptotic signaling pathway GO:0097191 1 0.012
monocarboxylic acid transport GO:0015718 3 0.012
regulation of ras protein signal transduction GO:0046578 93 0.012
positive regulation of macromolecule biosynthetic process GO:0010557 283 0.012
cell projection assembly GO:0030031 94 0.012
cellular response to molecule of bacterial origin GO:0071219 3 0.012
dorsal ventral pattern formation GO:0009953 133 0.012
anterior posterior axis specification embryo GO:0008595 103 0.012
positive regulation of transport GO:0051050 92 0.012
mitotic spindle organization GO:0007052 220 0.012
response to nutrient levels GO:0031667 114 0.012
response to hexose GO:0009746 3 0.012
positive regulation of cellular component organization GO:0051130 156 0.012
positive regulation of nervous system development GO:0051962 69 0.012
positive regulation of cellular catabolic process GO:0031331 95 0.012
photoreceptor cell differentiation GO:0046530 170 0.012
positive regulation of phosphorylation GO:0042327 87 0.012
regulation of developmental growth GO:0048638 174 0.012
metal ion transport GO:0030001 74 0.012
peptide biosynthetic process GO:0043043 42 0.012
response to endogenous stimulus GO:0009719 119 0.012
negative regulation of cellular component organization GO:0051129 108 0.012
protein maturation GO:0051604 71 0.012
multi organism behavior GO:0051705 175 0.012
apoptotic process GO:0006915 159 0.012
lipid metabolic process GO:0006629 121 0.012
positive regulation of purine nucleotide catabolic process GO:0033123 46 0.012
cell division GO:0051301 248 0.012
macromolecular complex assembly GO:0065003 256 0.012
protein modification by small protein conjugation or removal GO:0070647 106 0.012
sensory perception GO:0007600 196 0.012
regulation of proteolysis GO:0030162 87 0.011
epithelial tube morphogenesis GO:0060562 88 0.011
gene silencing GO:0016458 138 0.011
spinal cord development GO:0021510 1 0.011
response to nitrogen compound GO:1901698 90 0.011
negative regulation of cell differentiation GO:0045596 143 0.011
negative regulation of rna metabolic process GO:0051253 251 0.011
response to alcohol GO:0097305 95 0.011
positive regulation of lipid storage GO:0010884 4 0.011
cellular lipid metabolic process GO:0044255 83 0.011
nicotinamide nucleotide metabolic process GO:0046496 2 0.011
response to light stimulus GO:0009416 124 0.011
meiotic nuclear division GO:0007126 151 0.011
purine ribonucleoside triphosphate catabolic process GO:0009207 108 0.011
cellular response to lipopolysaccharide GO:0071222 3 0.011
compound eye photoreceptor development GO:0042051 78 0.011
guanosine containing compound metabolic process GO:1901068 74 0.011
response to organic cyclic compound GO:0014070 89 0.011
regulation of gtp catabolic process GO:0033124 44 0.011
positive regulation of proteolysis GO:0045862 52 0.011
cellular homeostasis GO:0019725 80 0.011
regulation of lipid transport GO:0032368 3 0.011
establishment of organelle localization GO:0051656 122 0.011
limb development GO:0060173 1 0.011
regulation of cellular response to stress GO:0080135 89 0.011
protein complex biogenesis GO:0070271 201 0.011
regulation of endocytosis GO:0030100 37 0.011
regulation of cell cycle process GO:0010564 181 0.011
mesenchymal cell development GO:0014031 1 0.011
purine nucleoside triphosphate catabolic process GO:0009146 108 0.011
cellular macromolecule localization GO:0070727 220 0.011
response to starvation GO:0042594 97 0.011
response to monosaccharide GO:0034284 4 0.011
cell growth GO:0016049 108 0.011
spermatid development GO:0007286 98 0.011
negative regulation of growth GO:0045926 84 0.010
camera type eye morphogenesis GO:0048593 2 0.010
epidermal growth factor receptor signaling pathway GO:0007173 58 0.010
androgen metabolic process GO:0008209 1 0.010
gtp metabolic process GO:0046039 72 0.010
tube morphogenesis GO:0035239 191 0.010
response to glucose GO:0009749 2 0.010
mating behavior GO:0007617 106 0.010
anterior posterior pattern specification GO:0009952 136 0.010
regulation of i kappab kinase nf kappab signaling GO:0043122 2 0.010
leg disc development GO:0035218 92 0.010
cation transport GO:0006812 110 0.010
cellular ketone metabolic process GO:0042180 24 0.010
tripartite regional subdivision GO:0007351 103 0.010
digestive system development GO:0055123 149 0.010
limb morphogenesis GO:0035108 1 0.010
negative regulation of nervous system development GO:0051961 92 0.010
response to copper ion GO:0046688 4 0.010
meiotic cell cycle GO:0051321 171 0.010
regulation of notch signaling pathway GO:0008593 100 0.010
intracellular protein transport GO:0006886 104 0.010
regulation of cell shape GO:0008360 113 0.010
wound healing GO:0042060 75 0.010
cytoplasmic transport GO:0016482 130 0.010
endomembrane system organization GO:0010256 119 0.010
cellular macromolecule catabolic process GO:0044265 136 0.010
digestive tract development GO:0048565 149 0.010
positive regulation of transcription from rna polymerase ii promoter GO:0045944 204 0.010
protein ubiquitination GO:0016567 70 0.010
dna metabolic process GO:0006259 227 0.010
positive regulation of apoptotic signaling pathway GO:2001235 4 0.010
regulation of protein modification process GO:0031399 112 0.010
wing disc pattern formation GO:0035222 66 0.010
immune effector process GO:0002252 98 0.010
ion transmembrane transport GO:0034220 122 0.010
single organism carbohydrate metabolic process GO:0044723 72 0.010
sensory perception of smell GO:0007608 80 0.010
dephosphorylation GO:0016311 51 0.010

CG32982 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in fly and predicted with the fly functional network.

Disease DO term ID Size Probability Func Analog Org
disease of anatomical entity DOID:7 0 0.072
nervous system disease DOID:863 0 0.022
disease of metabolism DOID:0014667 0 0.016
inherited metabolic disorder DOID:655 0 0.013
sensory system disease DOID:0050155 0 0.012
cancer DOID:162 0 0.012
disease of cellular proliferation DOID:14566 0 0.012
organ system cancer DOID:0050686 0 0.012
eye and adnexa disease DOID:1492 0 0.012
eye disease DOID:5614 0 0.011
cardiovascular system disease DOID:1287 0 0.011
musculoskeletal system disease DOID:17 0 0.010