Drosophila melanogaster

72 known processes

Upf1 (Dmel_CG1559)

CG1559 gene product from transcript CG1559-RA

(Aliases: Upf1p,DmUpf1,upf1,UPF1,Dm-Upf1,CG1559,Dmel\CG1559)

Upf1 biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
pole plasm mrna localization GO:0019094 49 0.671
regulation of transcription from rna polymerase ii promoter GO:0006357 378 0.491
protein modification process GO:0036211 438 0.473
chromosome organization GO:0051276 360 0.466
chorion containing eggshell formation GO:0007304 105 0.433
negative regulation of cellular biosynthetic process GO:0031327 277 0.404
positive regulation of nitrogen compound metabolic process GO:0051173 354 0.393
negative regulation of gene expression GO:0010629 387 0.388
positive regulation of nucleobase containing compound metabolic process GO:0045935 332 0.376
positive regulation of transcription from rna polymerase ii promoter GO:0045944 204 0.374
epithelial cell development GO:0002064 274 0.337
positive regulation of rna metabolic process GO:0051254 271 0.331
positive regulation of macromolecule metabolic process GO:0010604 405 0.322
negative regulation of cellular macromolecule biosynthetic process GO:2000113 267 0.315
positive regulation of biosynthetic process GO:0009891 316 0.307
positive regulation of gene expression GO:0010628 290 0.307
negative regulation of developmental process GO:0051093 201 0.283
negative regulation of biosynthetic process GO:0009890 277 0.265
transcription from rna polymerase ii promoter GO:0006366 368 0.244
positive regulation of nucleic acid templated transcription GO:1903508 266 0.220
negative regulation of cellular metabolic process GO:0031324 382 0.216
negative regulation of rna biosynthetic process GO:1902679 240 0.213
cellular catabolic process GO:0044248 372 0.203
negative regulation of macromolecule biosynthetic process GO:0010558 270 0.202
cellular protein modification process GO:0006464 438 0.197
columnar cuboidal epithelial cell differentiation GO:0002065 256 0.193
defense response GO:0006952 300 0.191
chromatin organization GO:0006325 207 0.190
rna localization GO:0006403 115 0.189
positive regulation of macromolecule biosynthetic process GO:0010557 283 0.182
positive regulation of transcription dna templated GO:0045893 266 0.180
establishment of localization in cell GO:0051649 402 0.170
positive regulation of response to stimulus GO:0048584 323 0.165
neuron projection guidance GO:0097485 241 0.157
response to biotic stimulus GO:0009607 294 0.146
positive regulation of rna biosynthetic process GO:1902680 266 0.142
positive regulation of cellular biosynthetic process GO:0031328 316 0.138
regulation of protein metabolic process GO:0051246 256 0.132
pole plasm assembly GO:0007315 61 0.130
defense response to other organism GO:0098542 225 0.127
oocyte differentiation GO:0009994 145 0.126
negative regulation of rna metabolic process GO:0051253 251 0.126
positive regulation of signaling GO:0023056 243 0.121
heterocycle catabolic process GO:0046700 166 0.121
negative regulation of nucleic acid templated transcription GO:1903507 240 0.120
epithelial cell differentiation GO:0030855 322 0.119
nucleobase containing compound catabolic process GO:0034655 165 0.118
oocyte axis specification GO:0007309 108 0.118
dna integrity checkpoint GO:0031570 81 0.115
positive regulation of cell communication GO:0010647 250 0.115
oocyte dorsal ventral axis specification GO:0007310 34 0.113
positive regulation of signal transduction GO:0009967 223 0.110
response to external biotic stimulus GO:0043207 293 0.108
negative regulation of nitrogen compound metabolic process GO:0051172 265 0.106
axon development GO:0061564 297 0.106
spermatid development GO:0007286 98 0.104
actin filament based process GO:0030029 220 0.100
hippo signaling GO:0035329 20 0.100
nuclear transcribed mrna catabolic process nonsense mediated decay GO:0000184 8 0.099
oocyte development GO:0048599 124 0.097
glycosyl compound catabolic process GO:1901658 112 0.096
dna damage checkpoint GO:0000077 78 0.092
regulation of multicellular organismal development GO:2000026 414 0.091
cellular response to chemical stimulus GO:0070887 199 0.091
regulation of cell differentiation GO:0045595 302 0.090
embryo development ending in birth or egg hatching GO:0009792 152 0.090
response to other organism GO:0051707 293 0.090
multi organism behavior GO:0051705 175 0.088
protein modification by small protein conjugation or removal GO:0070647 106 0.088
regulation of response to stress GO:0080134 200 0.087
maternal determination of anterior posterior axis embryo GO:0008358 74 0.087
ovarian follicle cell development GO:0030707 248 0.086
reproductive system development GO:0061458 74 0.078
purine ribonucleotide catabolic process GO:0009154 109 0.078
single organism intracellular transport GO:1902582 207 0.078
response to organic substance GO:0010033 284 0.077
defense response to bacterium GO:0042742 178 0.076
blastoderm segmentation GO:0007350 159 0.073
organophosphate metabolic process GO:0019637 195 0.073
negative regulation of nucleobase containing compound metabolic process GO:0045934 261 0.072
single organism catabolic process GO:0044712 228 0.071
catabolic process GO:0009056 409 0.070
innate immune response GO:0045087 144 0.069
protein maturation GO:0051604 71 0.069
chromatin modification GO:0016568 147 0.069
small molecule metabolic process GO:0044281 305 0.067
axon guidance GO:0007411 233 0.067
mitotic g2 m transition checkpoint GO:0044818 70 0.067
response to bacterium GO:0009617 198 0.066
protein transport GO:0015031 155 0.065
phosphorylation GO:0016310 294 0.065
cellular response to organic substance GO:0071310 132 0.065
taxis GO:0042330 304 0.065
growth GO:0040007 359 0.065
cation transport GO:0006812 110 0.064
positive regulation of phosphorus metabolic process GO:0010562 139 0.064
oocyte construction GO:0007308 112 0.063
regulation of cell development GO:0060284 215 0.063
reproductive structure development GO:0048608 74 0.063
germarium derived egg chamber formation GO:0007293 101 0.063
spermatid differentiation GO:0048515 114 0.062
negative regulation of transcription dna templated GO:0045892 237 0.061
regulation of nervous system development GO:0051960 248 0.061
axonogenesis GO:0007409 290 0.061
nucleoside triphosphate metabolic process GO:0009141 120 0.060
organonitrogen compound metabolic process GO:1901564 318 0.060
compound eye development GO:0048749 307 0.060
vesicle mediated transport GO:0016192 381 0.060
intracellular transport GO:0046907 228 0.059
regulation of cellular amine metabolic process GO:0033238 3 0.059
mitotic g2 dna damage checkpoint GO:0007095 69 0.058
single organism cellular localization GO:1902580 180 0.057
ribonucleoside triphosphate catabolic process GO:0009203 108 0.057
cellular macromolecule catabolic process GO:0044265 136 0.057
purine nucleoside triphosphate catabolic process GO:0009146 108 0.057
macromolecular complex assembly GO:0065003 256 0.056
mrna metabolic process GO:0016071 124 0.056
developmental growth GO:0048589 280 0.055
regulation of anatomical structure size GO:0090066 163 0.055
glycosyl compound metabolic process GO:1901657 127 0.055
covalent chromatin modification GO:0016569 106 0.055
membrane organization GO:0061024 112 0.055
positive regulation of cellular component organization GO:0051130 156 0.055
g2 dna damage checkpoint GO:0031572 69 0.052
purine nucleoside metabolic process GO:0042278 127 0.051
aromatic compound catabolic process GO:0019439 166 0.051
adherens junction assembly GO:0034333 11 0.051
morphogenesis of follicular epithelium GO:0016333 36 0.050
regulation of cellular amino acid metabolic process GO:0006521 0 0.050
negative regulation of cellular protein metabolic process GO:0032269 85 0.050
sex differentiation GO:0007548 81 0.050
embryonic pattern specification GO:0009880 174 0.049
lipid metabolic process GO:0006629 121 0.049
negative regulation of cell differentiation GO:0045596 143 0.049
compound eye morphogenesis GO:0001745 249 0.049
cell junction organization GO:0034330 57 0.048
immune response GO:0006955 246 0.047
cellular macromolecule localization GO:0070727 220 0.047
cell proliferation GO:0008283 299 0.047
actin filament organization GO:0007015 126 0.047
protein phosphorylation GO:0006468 169 0.047
purine ribonucleoside catabolic process GO:0046130 112 0.046
body morphogenesis GO:0010171 2 0.046
ribonucleoside metabolic process GO:0009119 127 0.046
small gtpase mediated signal transduction GO:0007264 88 0.046
ribonucleoside catabolic process GO:0042454 112 0.045
rna catabolic process GO:0006401 37 0.045
chemical homeostasis GO:0048878 92 0.045
endocytosis GO:0006897 310 0.045
developmental maturation GO:0021700 172 0.045
purine ribonucleoside triphosphate catabolic process GO:0009207 108 0.045
organic substance catabolic process GO:1901575 308 0.044
ion homeostasis GO:0050801 55 0.044
death GO:0016265 284 0.044
regulation of cell projection organization GO:0031344 92 0.044
response to abiotic stimulus GO:0009628 341 0.044
posttranscriptional regulation of gene expression GO:0010608 145 0.043
regulation of cellular protein metabolic process GO:0032268 243 0.043
positive regulation of multicellular organismal process GO:0051240 143 0.043
response to sterol GO:0036314 34 0.043
pole plasm rna localization GO:0007316 52 0.042
protein localization GO:0008104 284 0.042
regulation of gene expression epigenetic GO:0040029 128 0.041
synaptic transmission GO:0007268 288 0.041
regulation of apoptotic process GO:0042981 130 0.041
ras protein signal transduction GO:0007265 88 0.041
posttranscriptional gene silencing GO:0016441 46 0.041
carbohydrate derivative catabolic process GO:1901136 118 0.040
regionalization GO:0003002 416 0.040
oxoacid metabolic process GO:0043436 103 0.040
homeostatic process GO:0042592 199 0.040
nucleoside catabolic process GO:0009164 112 0.040
proteolysis GO:0006508 192 0.040
purine ribonucleoside triphosphate metabolic process GO:0009205 119 0.039
negative regulation of cell communication GO:0010648 223 0.039
protein complex biogenesis GO:0070271 201 0.039
cell cycle checkpoint GO:0000075 95 0.038
regulation of notch signaling pathway GO:0008593 100 0.038
regulation of immune response GO:0050776 118 0.038
single organism biosynthetic process GO:0044711 206 0.038
axis specification GO:0009798 167 0.038
nucleotide catabolic process GO:0009166 109 0.038
immune system process GO:0002376 347 0.038
golgi vesicle transport GO:0048193 27 0.037
negative regulation of mitotic cell cycle phase transition GO:1901991 103 0.037
developmental cell growth GO:0048588 52 0.037
cellular macromolecular complex assembly GO:0034622 153 0.036
eye development GO:0001654 323 0.036
regulation of catabolic process GO:0009894 170 0.036
establishment of protein localization GO:0045184 163 0.036
purine nucleoside catabolic process GO:0006152 112 0.036
response to ecdysone GO:0035075 34 0.036
mitotic dna integrity checkpoint GO:0044774 75 0.036
regulation of anatomical structure morphogenesis GO:0022603 242 0.035
nucleoside metabolic process GO:0009116 127 0.035
nucleotide metabolic process GO:0009117 161 0.035
endomembrane system organization GO:0010256 119 0.035
purine containing compound metabolic process GO:0072521 155 0.035
ion transport GO:0006811 145 0.035
peptidyl lysine modification GO:0018205 57 0.034
morphogenesis of a polarized epithelium GO:0001738 93 0.034
organic substance transport GO:0071702 257 0.034
tripartite regional subdivision GO:0007351 103 0.033
response to organic cyclic compound GO:0014070 89 0.033
purine ribonucleoside metabolic process GO:0046128 127 0.033
organophosphate catabolic process GO:0046434 112 0.033
positive regulation of protein modification process GO:0031401 58 0.033
positive regulation of cell death GO:0010942 69 0.033
synapse organization GO:0050808 196 0.032
cytoplasmic transport GO:0016482 130 0.032
regulation of ras protein signal transduction GO:0046578 93 0.032
nucleoside triphosphate catabolic process GO:0009143 108 0.032
regulation of cell morphogenesis GO:0022604 163 0.032
regulation of neuron projection development GO:0010975 69 0.032
ribonucleotide catabolic process GO:0009261 109 0.032
embryonic axis specification GO:0000578 107 0.032
connective tissue development GO:0061448 3 0.032
germarium derived oocyte fate determination GO:0007294 26 0.032
appendage morphogenesis GO:0035107 397 0.031
cellular amine metabolic process GO:0044106 12 0.031
rna processing GO:0006396 147 0.031
purine nucleotide catabolic process GO:0006195 109 0.031
purine containing compound catabolic process GO:0072523 112 0.031
cell death GO:0008219 279 0.031
multicellular organismal homeostasis GO:0048871 41 0.030
muscle structure development GO:0061061 224 0.030
positive regulation of developmental process GO:0051094 143 0.030
positive regulation of phosphorylation GO:0042327 87 0.030
regulation of intracellular signal transduction GO:1902531 236 0.029
nucleoside phosphate metabolic process GO:0006753 162 0.029
protein catabolic process GO:0030163 101 0.029
positive regulation of cellular amine metabolic process GO:0033240 0 0.029
ribose phosphate metabolic process GO:0019693 145 0.029
response to alcohol GO:0097305 95 0.029
regulation of transport GO:0051049 181 0.029
protein processing GO:0016485 68 0.029
response to oxygen containing compound GO:1901700 200 0.029
gene silencing GO:0016458 138 0.029
negative regulation of protein metabolic process GO:0051248 85 0.029
regulation of gtpase activity GO:0043087 44 0.029
regulation of purine nucleotide metabolic process GO:1900542 62 0.029
gonad development GO:0008406 50 0.029
regulation of growth GO:0040008 233 0.028
negative regulation of transcription from rna polymerase ii promoter GO:0000122 119 0.028
embryonic development via the syncytial blastoderm GO:0001700 148 0.028
cell projection assembly GO:0030031 94 0.028
positive regulation of cellular catabolic process GO:0031331 95 0.028
mitotic dna damage checkpoint GO:0044773 74 0.028
eye morphogenesis GO:0048592 260 0.028
regulation of catalytic activity GO:0050790 185 0.027
regulation of small gtpase mediated signal transduction GO:0051056 93 0.027
columnar cuboidal epithelial cell development GO:0002066 249 0.027
purine nucleotide metabolic process GO:0006163 146 0.027
cellular protein catabolic process GO:0044257 83 0.027
ion transmembrane transport GO:0034220 122 0.027
carboxylic acid metabolic process GO:0019752 92 0.027
positive regulation of cellular component biogenesis GO:0044089 80 0.027
regulation of molecular function GO:0065009 217 0.027
cellular amino acid metabolic process GO:0006520 61 0.027
mrna catabolic process GO:0006402 33 0.026
protein modification by small protein conjugation GO:0032446 79 0.026
regulation of organelle organization GO:0033043 196 0.026
oocyte anterior posterior axis specification GO:0007314 72 0.026
stem cell development GO:0048864 79 0.026
regulation of protein modification process GO:0031399 112 0.026
positive regulation of cellular amino acid metabolic process GO:0045764 0 0.026
negative regulation of cell cycle process GO:0010948 109 0.026
cellular ketone metabolic process GO:0042180 24 0.026
cellular lipid metabolic process GO:0044255 83 0.026
regulation of multi organism process GO:0043900 131 0.026
locomotory behavior GO:0007626 176 0.025
post embryonic appendage morphogenesis GO:0035120 385 0.025
gtp catabolic process GO:0006184 72 0.025
secretion by cell GO:0032940 101 0.025
regulation of cellular ketone metabolic process GO:0010565 3 0.025
regulation of hydrolase activity GO:0051336 97 0.025
negative regulation of response to stimulus GO:0048585 258 0.025
nucleoside phosphate catabolic process GO:1901292 110 0.025
positive regulation of phosphate metabolic process GO:0045937 139 0.025
negative regulation of mitotic cell cycle GO:0045930 109 0.025
single organism membrane organization GO:0044802 93 0.025
organonitrogen compound catabolic process GO:1901565 128 0.025
organic acid metabolic process GO:0006082 103 0.025
macromolecule catabolic process GO:0009057 161 0.025
multicellular organismal aging GO:0010259 140 0.024
purine ribonucleotide metabolic process GO:0009150 145 0.024
pigment metabolic process GO:0042440 84 0.024
regulation of phosphorus metabolic process GO:0051174 210 0.024
intracellular signal transduction GO:0035556 300 0.024
anterior posterior pattern specification GO:0009952 136 0.024
establishment or maintenance of cell polarity GO:0007163 167 0.024
positive regulation of intracellular signal transduction GO:1902533 116 0.024
regulation of wnt signaling pathway GO:0030111 68 0.023
phagocytosis GO:0006909 215 0.023
regulation of vesicle mediated transport GO:0060627 59 0.023
regulation of cell shape GO:0008360 113 0.023
peptidyl amino acid modification GO:0018193 105 0.023
cellular protein localization GO:0034613 160 0.023
regulation of protein complex assembly GO:0043254 42 0.023
eggshell formation GO:0030703 105 0.023
cell maturation GO:0048469 144 0.023
regulation of cellular component biogenesis GO:0044087 201 0.023
regulation of developmental growth GO:0048638 174 0.022
response to temperature stimulus GO:0009266 106 0.022
positive regulation of catalytic activity GO:0043085 118 0.022
male gamete generation GO:0048232 201 0.022
open tracheal system development GO:0007424 204 0.022
stem cell differentiation GO:0048863 117 0.022
determination of adult lifespan GO:0008340 137 0.022
negative regulation of signal transduction GO:0009968 206 0.022
nuclear division GO:0000280 332 0.021
guanosine containing compound catabolic process GO:1901069 74 0.021
histone modification GO:0016570 106 0.021
development of primary sexual characteristics GO:0045137 50 0.021
gene silencing by rna GO:0031047 57 0.021
transmembrane transport GO:0055085 139 0.021
chromosome segregation GO:0007059 157 0.021
pole plasm oskar mrna localization GO:0045451 46 0.021
negative regulation of multicellular organismal process GO:0051241 142 0.021
stem cell maintenance GO:0019827 67 0.021
ribonucleoside triphosphate metabolic process GO:0009199 119 0.020
actin cytoskeleton organization GO:0030036 206 0.020
amine metabolic process GO:0009308 12 0.020
dna replication GO:0006260 48 0.020
germ line cyst formation GO:0048134 44 0.020
protein complex assembly GO:0006461 200 0.020
regulation of programmed cell death GO:0043067 152 0.020
dorsal ventral axis specification GO:0009950 66 0.020
dna metabolic process GO:0006259 227 0.020
wnt signaling pathway GO:0016055 98 0.020
positive regulation of hydrolase activity GO:0051345 78 0.020
response to endogenous stimulus GO:0009719 119 0.020
cellular amide metabolic process GO:0043603 80 0.019
appendage development GO:0048736 401 0.019
segmentation GO:0035282 207 0.019
centrosome organization GO:0051297 163 0.019
negative regulation of nervous system development GO:0051961 92 0.019
cell cycle phase transition GO:0044770 140 0.019
positive regulation of molecular function GO:0044093 136 0.019
intracellular mrna localization involved in anterior posterior axis specification GO:0060811 53 0.019
ovarian follicle cell migration GO:0007297 121 0.019
regulation of cell death GO:0010941 173 0.019
defense response to gram negative bacterium GO:0050829 94 0.019
posttranscriptional gene silencing by rna GO:0035194 45 0.019
regulation of mitotic cell cycle phase transition GO:1901990 130 0.019
regulation of translation GO:0006417 56 0.019
regulation of cell cycle phase transition GO:1901987 130 0.019
regulation of immune system process GO:0002682 176 0.019
regulation of cellular localization GO:0060341 136 0.019
regulation of cellular catabolic process GO:0031329 157 0.018
regulation of response to external stimulus GO:0032101 115 0.018
extrinsic apoptotic signaling pathway GO:0097191 1 0.018
anterior posterior axis specification GO:0009948 109 0.018
response to lipopolysaccharide GO:0032496 4 0.018
purine nucleoside triphosphate metabolic process GO:0009144 119 0.018
protein acylation GO:0043543 42 0.018
regulation of phosphorylation GO:0042325 147 0.018
negative regulation of cellular component organization GO:0051129 108 0.018
regulation of gtp catabolic process GO:0033124 44 0.018
cellular nitrogen compound catabolic process GO:0044270 165 0.018
histone methylation GO:0016571 40 0.018
positive regulation of growth GO:0045927 75 0.017
regulation of cellular response to stress GO:0080135 89 0.017
regulation of ras gtpase activity GO:0032318 38 0.017
single organismal cell cell adhesion GO:0016337 45 0.017
regulation of synapse assembly GO:0051963 94 0.017
secretion GO:0046903 109 0.017
oocyte microtubule cytoskeleton organization GO:0016325 35 0.017
establishment of cell polarity GO:0030010 40 0.017
establishment or maintenance of polarity of follicular epithelium GO:0016334 26 0.017
developmental programmed cell death GO:0010623 138 0.017
cellular homeostasis GO:0019725 80 0.017
molting cycle process GO:0022404 29 0.017
positive regulation of cellular protein metabolic process GO:0032270 118 0.017
protein ubiquitination GO:0016567 70 0.017
regulation of peptidase activity GO:0052547 39 0.017
tissue death GO:0016271 102 0.017
chaeta development GO:0022416 97 0.016
response to nutrient levels GO:0031667 114 0.016
wing disc morphogenesis GO:0007472 344 0.016
organelle fission GO:0048285 340 0.016
rna splicing GO:0008380 83 0.016
positive regulation of transport GO:0051050 92 0.016
response to extracellular stimulus GO:0009991 116 0.016
reproductive behavior GO:0019098 122 0.016
histolysis GO:0007559 102 0.016
mapk cascade GO:0000165 107 0.015
respiratory system development GO:0060541 213 0.015
negative regulation of cell cycle GO:0045786 116 0.015
mitotic nuclear division GO:0007067 213 0.015
positive regulation of organelle organization GO:0010638 65 0.015
regulation of cellular component size GO:0032535 98 0.015
cellular protein complex assembly GO:0043623 71 0.015
positive regulation of nucleotide catabolic process GO:0030813 46 0.015
mrna processing GO:0006397 104 0.015
nucleus organization GO:0006997 45 0.015
regulation of cell proliferation GO:0042127 163 0.015
developmental growth involved in morphogenesis GO:0060560 65 0.015
gtp metabolic process GO:0046039 72 0.015
regulation of cell cycle process GO:0010564 181 0.015
cellular response to decreased oxygen levels GO:0036294 30 0.015
proteolysis involved in cellular protein catabolic process GO:0051603 83 0.015
chemotaxis GO:0006935 249 0.015
positive regulation of gtp catabolic process GO:0033126 43 0.014
cytoplasm organization GO:0007028 64 0.014
mitotic cell cycle checkpoint GO:0007093 88 0.014
cellular response to dna damage stimulus GO:0006974 223 0.014
notch signaling pathway GO:0007219 120 0.014
regulation of nurse cell apoptotic process GO:0045477 9 0.014
muscle organ development GO:0007517 127 0.014
regulation of phosphate metabolic process GO:0019220 210 0.014
response to lipid GO:0033993 38 0.014
regulation of chromosome organization GO:0033044 64 0.014
peptidyl lysine acetylation GO:0018394 39 0.013
negative regulation of protein processing GO:0010955 31 0.013
sensory organ morphogenesis GO:0090596 260 0.013
establishment of monopolar cell polarity GO:0061162 15 0.013
modification dependent protein catabolic process GO:0019941 78 0.013
anterior posterior axis specification embryo GO:0008595 103 0.013
cation homeostasis GO:0055080 51 0.013
cell growth GO:0016049 108 0.013
regulation of ion transport GO:0043269 39 0.013
neurological system process GO:0050877 358 0.013
positive regulation of gtpase activity GO:0043547 43 0.013
spermatogenesis GO:0007283 200 0.013
histone lysine methylation GO:0034968 32 0.013
negative regulation of cell death GO:0060548 81 0.013
cell cell junction organization GO:0045216 55 0.013
cellular response to starvation GO:0009267 61 0.013
cellular chemical homeostasis GO:0055082 40 0.013
cellular response to oxygen containing compound GO:1901701 79 0.013
regulation of nucleoside metabolic process GO:0009118 50 0.012
mitotic cell cycle phase transition GO:0044772 138 0.012
negative regulation of cell cycle phase transition GO:1901988 103 0.012
negative regulation of cell development GO:0010721 62 0.012
organic cyclic compound catabolic process GO:1901361 168 0.012
guanosine containing compound metabolic process GO:1901068 74 0.012
genitalia development GO:0048806 26 0.012
female germ line cyst formation GO:0048135 42 0.012
germarium derived oocyte differentiation GO:0030706 29 0.012
cellular cation homeostasis GO:0030003 38 0.012
cell junction assembly GO:0034329 42 0.012
cellular component assembly involved in morphogenesis GO:0010927 151 0.012
carbohydrate derivative metabolic process GO:1901135 217 0.012
negative regulation of translation GO:0017148 28 0.012
response to radiation GO:0009314 155 0.012
aging GO:0007568 143 0.012
response to nitrogen compound GO:1901698 90 0.012
cellular response to abiotic stimulus GO:0071214 58 0.012
regulation of cell substrate adhesion GO:0010810 2 0.012
ribonucleoprotein complex biogenesis GO:0022613 31 0.012
regulation of chromatin modification GO:1903308 28 0.012
regulation of mapk cascade GO:0043408 92 0.012
triglyceride biosynthetic process GO:0019432 2 0.012
positive regulation of apoptotic signaling pathway GO:2001235 4 0.012
skeletal muscle fiber development GO:0048741 3 0.012
single organism cell adhesion GO:0098602 47 0.011
regulation of mitotic cell cycle GO:0007346 190 0.011
negative regulation of proteolysis GO:0045861 31 0.011
protein secretion GO:0009306 45 0.011
positive regulation of cell differentiation GO:0045597 64 0.011
eggshell chorion assembly GO:0007306 66 0.011
protein targeting GO:0006605 64 0.011
chaeta morphogenesis GO:0008407 42 0.011
defense response to fungus GO:0050832 48 0.011
negative regulation of signaling GO:0023057 219 0.011
regulation of cell cycle g1 s phase transition GO:1902806 23 0.011
regulation of cell cycle GO:0051726 291 0.011
non sensory hair organization GO:0035316 47 0.011
macromolecule methylation GO:0043414 45 0.011
myotube cell development GO:0014904 3 0.011
regulation of endopeptidase activity GO:0052548 36 0.011
cellular ion homeostasis GO:0006873 39 0.011
translation GO:0006412 69 0.011
protein alkylation GO:0008213 43 0.011
regulation of protein processing GO:0070613 32 0.011
negative regulation of catalytic activity GO:0043086 42 0.011
nls bearing protein import into nucleus GO:0006607 5 0.011
digestive tract development GO:0048565 149 0.010
mitochondrion organization GO:0007005 65 0.010
signal transduction by phosphorylation GO:0023014 107 0.010
positive regulation of purine nucleotide catabolic process GO:0033123 46 0.010
epidermal cell differentiation GO:0009913 51 0.010
positive regulation of cell development GO:0010720 61 0.010
regulation of mrna processing GO:0050684 71 0.010
proteasome mediated ubiquitin dependent protein catabolic process GO:0043161 54 0.010
methylation GO:0032259 47 0.010
regulation of proteolysis GO:0030162 87 0.010
regulation of protein catabolic process GO:0042176 55 0.010
adherens junction organization GO:0034332 27 0.010

Upf1 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in fly and predicted with the fly functional network.

Disease DO term ID Size Probability Func Analog Org
disease of anatomical entity DOID:7 0 0.108
cancer DOID:162 0 0.026
disease of cellular proliferation DOID:14566 0 0.026
nervous system disease DOID:863 0 0.026
cardiovascular system disease DOID:1287 0 0.014
organ system cancer DOID:0050686 0 0.012
central nervous system disease DOID:331 0 0.011