Drosophila melanogaster

30 known processes

Tis11 (Dmel_CG4070)

Tis11 homolog

(Aliases: dTTP,anon-EST:Liang-1.28,TIS11,CG4070,clone 1.28,TIS11cc1,DTIS11,TIScc1,Dmel\CG4070,dTis11,l(1)G0124)

Tis11 biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
imaginal disc derived appendage morphogenesis GO:0035114 395 0.236
imaginal disc derived appendage development GO:0048737 399 0.192
appendage morphogenesis GO:0035107 397 0.183
cell proliferation GO:0008283 299 0.178
neurological system process GO:0050877 358 0.175
post embryonic appendage morphogenesis GO:0035120 385 0.160
organonitrogen compound metabolic process GO:1901564 318 0.159
regulation of cell cycle GO:0051726 291 0.154
response to abiotic stimulus GO:0009628 341 0.153
appendage development GO:0048736 401 0.127
regulation of cell differentiation GO:0045595 302 0.123
Mouse
single organism behavior GO:0044708 391 0.122
heterocycle catabolic process GO:0046700 166 0.119
Human Mouse
wing disc morphogenesis GO:0007472 344 0.119
cellular nitrogen compound catabolic process GO:0044270 165 0.111
Human Mouse
response to nutrient levels GO:0031667 114 0.107
Human
imaginal disc derived wing morphogenesis GO:0007476 337 0.106
organic substance catabolic process GO:1901575 308 0.102
Human Mouse
purine ribonucleoside metabolic process GO:0046128 127 0.101
glycosyl compound metabolic process GO:1901657 127 0.097
single organism catabolic process GO:0044712 228 0.095
small molecule metabolic process GO:0044281 305 0.095
response to extracellular stimulus GO:0009991 116 0.093
Human
ribonucleotide catabolic process GO:0009261 109 0.091
nucleoside triphosphate metabolic process GO:0009141 120 0.090
enzyme linked receptor protein signaling pathway GO:0007167 179 0.090
regulation of protein metabolic process GO:0051246 256 0.087
Mouse
aromatic compound catabolic process GO:0019439 166 0.085
Human Mouse
response to organic substance GO:0010033 284 0.085
nucleobase containing small molecule metabolic process GO:0055086 174 0.082
negative regulation of cellular metabolic process GO:0031324 382 0.081
Human Mouse
carbohydrate derivative metabolic process GO:1901135 217 0.080
regulation of cell cycle process GO:0010564 181 0.079
nucleotide metabolic process GO:0009117 161 0.078
sensory perception GO:0007600 196 0.078
positive regulation of nitrogen compound metabolic process GO:0051173 354 0.076
Human Mouse
regulation of cell development GO:0060284 215 0.075
salivary gland development GO:0007431 162 0.075
nucleoside catabolic process GO:0009164 112 0.074
phosphorylation GO:0016310 294 0.074
cellular catabolic process GO:0044248 372 0.073
Human Mouse
nucleotide catabolic process GO:0009166 109 0.071
nucleoside phosphate metabolic process GO:0006753 162 0.071
nucleoside phosphate catabolic process GO:1901292 110 0.070
purine ribonucleotide metabolic process GO:0009150 145 0.069
synaptic transmission GO:0007268 288 0.069
endocytosis GO:0006897 310 0.068
ribonucleoside catabolic process GO:0042454 112 0.067
negative regulation of cell cycle phase transition GO:1901988 103 0.065
purine nucleotide metabolic process GO:0006163 146 0.064
positive regulation of macromolecule metabolic process GO:0010604 405 0.063
Human Mouse
guanosine containing compound catabolic process GO:1901069 74 0.063
purine nucleotide catabolic process GO:0006195 109 0.063
negative regulation of cell cycle GO:0045786 116 0.063
nucleobase containing compound catabolic process GO:0034655 165 0.063
Human Mouse
multi multicellular organism process GO:0044706 123 0.062
organophosphate metabolic process GO:0019637 195 0.062
purine containing compound metabolic process GO:0072521 155 0.061
eye morphogenesis GO:0048592 260 0.061
taxis GO:0042330 304 0.060
purine nucleoside metabolic process GO:0042278 127 0.060
cellular response to chemical stimulus GO:0070887 199 0.058
rho protein signal transduction GO:0007266 14 0.058
organelle fission GO:0048285 340 0.058
gtp catabolic process GO:0006184 72 0.058
purine nucleoside triphosphate metabolic process GO:0009144 119 0.057
ribonucleoside metabolic process GO:0009119 127 0.057
spindle organization GO:0007051 253 0.057
negative regulation of cell cycle process GO:0010948 109 0.057
long term memory GO:0007616 62 0.055
purine nucleoside catabolic process GO:0006152 112 0.053
organelle localization GO:0051640 148 0.053
glycosyl compound catabolic process GO:1901658 112 0.053
phagocytosis GO:0006909 215 0.053
actin filament based process GO:0030029 220 0.052
actin cytoskeleton organization GO:0030036 206 0.052
positive regulation of macromolecule biosynthetic process GO:0010557 283 0.051
cell death GO:0008219 279 0.051
guanosine containing compound metabolic process GO:1901068 74 0.051
purine ribonucleoside triphosphate catabolic process GO:0009207 108 0.049
locomotory behavior GO:0007626 176 0.048
catabolic process GO:0009056 409 0.048
Human Mouse
eye development GO:0001654 323 0.048
multi organism reproductive behavior GO:0044705 121 0.047
central nervous system development GO:0007417 201 0.047
regulation of cellular localization GO:0060341 136 0.047
regulation of hydrolase activity GO:0051336 97 0.046
gtp metabolic process GO:0046039 72 0.046
nucleoside triphosphate catabolic process GO:0009143 108 0.046
regulation of mitotic cell cycle GO:0007346 190 0.044
actin filament organization GO:0007015 126 0.044
organelle fusion GO:0048284 46 0.044
organic cyclic compound catabolic process GO:1901361 168 0.044
Human Mouse
cell migration GO:0016477 238 0.044
compound eye photoreceptor cell differentiation GO:0001751 140 0.044
tissue death GO:0016271 102 0.043
compound eye development GO:0048749 307 0.043
regulation of nucleotide catabolic process GO:0030811 48 0.043
regulation of anatomical structure morphogenesis GO:0022603 242 0.041
photoreceptor cell differentiation GO:0046530 170 0.041
sensory organ morphogenesis GO:0090596 260 0.040
organonitrogen compound catabolic process GO:1901565 128 0.040
carbohydrate derivative catabolic process GO:1901136 118 0.040
negative regulation of cellular biosynthetic process GO:0031327 277 0.040
Human Mouse
cell motility GO:0048870 251 0.039
positive regulation of cellular biosynthetic process GO:0031328 316 0.039
single organism membrane fusion GO:0044801 42 0.039
cellular response to dna damage stimulus GO:0006974 223 0.039
nucleoside metabolic process GO:0009116 127 0.038
regulation of multicellular organismal development GO:2000026 414 0.038
Mouse
regulation of phosphate metabolic process GO:0019220 210 0.038
mitotic spindle organization GO:0007052 220 0.038
developmental programmed cell death GO:0010623 138 0.037
purine nucleoside triphosphate catabolic process GO:0009146 108 0.037
carboxylic acid metabolic process GO:0019752 92 0.037
regulation of transport GO:0051049 181 0.037
ribonucleotide metabolic process GO:0009259 145 0.037
ras protein signal transduction GO:0007265 88 0.037
purine ribonucleoside catabolic process GO:0046130 112 0.036
muscle cell differentiation GO:0042692 103 0.036
regulation of molecular function GO:0065009 217 0.036
translation GO:0006412 69 0.035
Mouse
establishment of organelle localization GO:0051656 122 0.035
single organism biosynthetic process GO:0044711 206 0.035
oocyte differentiation GO:0009994 145 0.035
negative regulation of cellular component organization GO:0051129 108 0.034
regulation of small gtpase mediated signal transduction GO:0051056 93 0.034
muscle structure development GO:0061061 224 0.034
positive regulation of molecular function GO:0044093 136 0.034
gland development GO:0048732 191 0.034
detection of abiotic stimulus GO:0009582 66 0.033
protein localization GO:0008104 284 0.033
imaginal disc derived wing vein morphogenesis GO:0008586 44 0.033
positive regulation of gtpase activity GO:0043547 43 0.033
response to organophosphorus GO:0046683 2 0.033
regulation of localization GO:0032879 275 0.033
detection of stimulus GO:0051606 156 0.033
positive regulation of gtp catabolic process GO:0033126 43 0.032
regulation of phosphorus metabolic process GO:0051174 210 0.032
protein phosphorylation GO:0006468 169 0.032
positive regulation of signaling GO:0023056 243 0.032
open tracheal system development GO:0007424 204 0.031
spindle elongation GO:0051231 83 0.031
compound eye morphogenesis GO:0001745 249 0.030
body morphogenesis GO:0010171 2 0.030
pole plasm oskar mrna localization GO:0045451 46 0.030
regulation of cell proliferation GO:0042127 163 0.030
regulation of organelle organization GO:0033043 196 0.030
response to endogenous stimulus GO:0009719 119 0.030
secretion GO:0046903 109 0.029
programmed cell death GO:0012501 257 0.029
eye photoreceptor cell development GO:0042462 81 0.029
organic substance transport GO:0071702 257 0.029
negative regulation of protein metabolic process GO:0051248 85 0.029
Mouse
negative regulation of g1 s transition of mitotic cell cycle GO:2000134 13 0.029
eye antennal disc development GO:0035214 60 0.029
exocrine system development GO:0035272 162 0.029
regulation of ras protein signal transduction GO:0046578 93 0.028
regulation of apoptotic process GO:0042981 130 0.028
negative regulation of cellular protein metabolic process GO:0032269 85 0.028
Mouse
positive regulation of phosphorus metabolic process GO:0010562 139 0.028
ribonucleoside triphosphate catabolic process GO:0009203 108 0.028
negative regulation of developmental process GO:0051093 201 0.028
Mouse
intracellular signal transduction GO:0035556 300 0.028
Mouse
cognition GO:0050890 141 0.028
response to temperature stimulus GO:0009266 106 0.028
positive regulation of cell communication GO:0010647 250 0.028
regulation of growth GO:0040008 233 0.028
mitotic cell cycle phase transition GO:0044772 138 0.027
positive regulation of cell motility GO:2000147 3 0.027
camera type eye development GO:0043010 4 0.027
regionalization GO:0003002 416 0.027
regulation of cell morphogenesis involved in differentiation GO:0010769 61 0.027
lipid metabolic process GO:0006629 121 0.027
autophagic cell death GO:0048102 83 0.027
regulation of nervous system development GO:0051960 248 0.027
nitrogen compound transport GO:0071705 85 0.027
cell cycle phase transition GO:0044770 140 0.027
regulation of cell death GO:0010941 173 0.026
regulation of embryonic development GO:0045995 68 0.026
single organism membrane organization GO:0044802 93 0.026
regulation of intracellular signal transduction GO:1902531 236 0.025
multi organism behavior GO:0051705 175 0.025
regulation of cellular response to stress GO:0080135 89 0.025
positive regulation of response to stimulus GO:0048584 323 0.025
regulation of cellular protein metabolic process GO:0032268 243 0.025
Mouse
negative regulation of nervous system development GO:0051961 92 0.025
regulation of gtp catabolic process GO:0033124 44 0.025
oocyte development GO:0048599 124 0.025
negative regulation of macromolecule biosynthetic process GO:0010558 270 0.025
Human Mouse
aging GO:0007568 143 0.025
regulation of multi organism process GO:0043900 131 0.025
regulation of mitotic cell cycle phase transition GO:1901990 130 0.025
meiotic cell cycle GO:0051321 171 0.025
organelle assembly GO:0070925 198 0.024
regulation of catalytic activity GO:0050790 185 0.024
stress activated mapk cascade GO:0051403 52 0.024
positive regulation of catalytic activity GO:0043085 118 0.024
response to lipopolysaccharide GO:0032496 4 0.024
ribonucleoside triphosphate metabolic process GO:0009199 119 0.024
positive regulation of gene expression GO:0010628 290 0.024
Human Mouse
positive regulation of cell migration GO:0030335 2 0.024
negative regulation of multicellular organismal process GO:0051241 142 0.024
Mouse
actin filament bundle organization GO:0061572 28 0.024
salivary gland histolysis GO:0035070 88 0.023
response to reactive oxygen species GO:0000302 24 0.023
rhabdomere development GO:0042052 38 0.023
axon guidance GO:0007411 233 0.023
negative regulation of transcription dna templated GO:0045892 237 0.023
Human Mouse
rna localization GO:0006403 115 0.023
cellular protein modification process GO:0006464 438 0.023
regulation of cell cycle phase transition GO:1901987 130 0.023
negative regulation of cellular macromolecule biosynthetic process GO:2000113 267 0.023
Human Mouse
gland morphogenesis GO:0022612 145 0.023
nucleus localization GO:0051647 34 0.023
regulation of synapse assembly GO:0051963 94 0.023
eye photoreceptor cell differentiation GO:0001754 145 0.023
death GO:0016265 284 0.023
positive regulation of secretion GO:0051047 22 0.023
regulation of cell division GO:0051302 72 0.023
muscle organ development GO:0007517 127 0.022
negative regulation of growth GO:0045926 84 0.022
immune response regulating signaling pathway GO:0002764 2 0.022
nucleus organization GO:0006997 45 0.022
cellular macromolecule localization GO:0070727 220 0.022
salivary gland morphogenesis GO:0007435 145 0.022
vesicle mediated transport GO:0016192 381 0.022
cell aging GO:0007569 2 0.021
regulation of gtpase activity GO:0043087 44 0.021
regulation of secretion GO:0051046 44 0.021
cellular response to extracellular stimulus GO:0031668 64 0.021
germarium derived female germ line cyst formation GO:0030727 42 0.021
golgi organization GO:0007030 66 0.021
mitotic g2 dna damage checkpoint GO:0007095 69 0.021
secretion by cell GO:0032940 101 0.021
transmembrane receptor protein serine threonine kinase signaling pathway GO:0007178 65 0.021
regulation of response to stress GO:0080134 200 0.021
Mouse
female germ line cyst formation GO:0048135 42 0.021
regulation of phosphorylation GO:0042325 147 0.020
mapk cascade GO:0000165 107 0.020
positive regulation of rho gtpase activity GO:0032321 19 0.020
histone modification GO:0016570 106 0.020
oxoacid metabolic process GO:0043436 103 0.020
endomembrane system organization GO:0010256 119 0.020
cell division GO:0051301 248 0.020
eye pigment granule organization GO:0008057 12 0.020
positive regulation of transcription from rna polymerase ii promoter GO:0045944 204 0.020
response to light stimulus GO:0009416 124 0.020
positive regulation of nucleotide metabolic process GO:0045981 55 0.020
response to other organism GO:0051707 293 0.020
membrane lipid metabolic process GO:0006643 22 0.020
regulation of neuron differentiation GO:0045664 103 0.019
ribose phosphate metabolic process GO:0019693 145 0.019
positive regulation of intracellular signal transduction GO:1902533 116 0.019
immune system process GO:0002376 347 0.019
Mouse
macroautophagy GO:0016236 42 0.019
neuron projection guidance GO:0097485 241 0.019
negative regulation of mitotic cell cycle phase transition GO:1901991 103 0.019
maintenance of location GO:0051235 73 0.019
multicellular organismal reproductive behavior GO:0033057 110 0.019
salivary gland cell autophagic cell death GO:0035071 83 0.019
regulation of cellular component biogenesis GO:0044087 201 0.019
positive regulation of phosphate metabolic process GO:0045937 139 0.019
dendrite development GO:0016358 204 0.019
positive regulation of transport GO:0051050 92 0.019
telencephalon development GO:0021537 2 0.019
membrane organization GO:0061024 112 0.018
positive regulation of cellular component organization GO:0051130 156 0.018
pole plasm assembly GO:0007315 61 0.018
regulation of purine nucleotide catabolic process GO:0033121 48 0.018
establishment of nucleus localization GO:0040023 26 0.018
female meiotic division GO:0007143 70 0.018
protein modification process GO:0036211 438 0.018
negative regulation of signaling GO:0023057 219 0.018
cellular lipid metabolic process GO:0044255 83 0.018
positive regulation of rna metabolic process GO:0051254 271 0.018
Human Mouse
respiratory system development GO:0060541 213 0.018
epidermal growth factor receptor signaling pathway GO:0007173 58 0.018
cytoplasm organization GO:0007028 64 0.018
histolysis GO:0007559 102 0.018
pigmentation GO:0043473 75 0.018
cellular amine metabolic process GO:0044106 12 0.018
purine ribonucleoside triphosphate metabolic process GO:0009205 119 0.018
negative regulation of cell communication GO:0010648 223 0.018
female meiosis chromosome segregation GO:0016321 33 0.018
regulation of nucleoside metabolic process GO:0009118 50 0.017
regulation of purine nucleotide metabolic process GO:1900542 62 0.017
g2 dna damage checkpoint GO:0031572 69 0.017
regulation of notch signaling pathway GO:0008593 100 0.017
meiotic nuclear division GO:0007126 151 0.017
regulation of translation GO:0006417 56 0.017
Mouse
organophosphate catabolic process GO:0046434 112 0.017
positive regulation of biosynthetic process GO:0009891 316 0.017
phagolysosome assembly GO:0001845 2 0.017
regulation of rho protein signal transduction GO:0035023 20 0.017
organic acid metabolic process GO:0006082 103 0.017
negative regulation of response to stimulus GO:0048585 258 0.017
Mouse
response to starvation GO:0042594 97 0.017
Human
axon development GO:0061564 297 0.017
actomyosin structure organization GO:0031032 56 0.017
response to oxygen containing compound GO:1901700 200 0.017
ribonucleoprotein complex subunit organization GO:0071826 28 0.017
purine containing compound catabolic process GO:0072523 112 0.017
endosome to lysosome transport GO:0008333 7 0.016
positive regulation of signal transduction GO:0009967 223 0.016
positive regulation of catabolic process GO:0009896 105 0.016
Human Mouse
cell cycle dna replication GO:0044786 23 0.016
cortical actin cytoskeleton organization GO:0030866 24 0.016
lateral inhibition GO:0046331 206 0.016
internal protein amino acid acetylation GO:0006475 38 0.016
macromolecular complex assembly GO:0065003 256 0.016
compound eye photoreceptor development GO:0042051 78 0.016
mitotic g2 m transition checkpoint GO:0044818 70 0.016
regulation of developmental growth GO:0048638 174 0.016
photoreceptor cell development GO:0042461 96 0.016
negative regulation of cell cycle g1 s phase transition GO:1902807 13 0.016
oocyte microtubule cytoskeleton organization GO:0016325 35 0.016
anterior posterior axis specification embryo GO:0008595 103 0.016
regulation of nucleotide metabolic process GO:0006140 62 0.016
regulation of mapk cascade GO:0043408 92 0.016
negative regulation of translation GO:0017148 28 0.016
Mouse
mitotic nuclear division GO:0007067 213 0.016
negative regulation of nitrogen compound metabolic process GO:0051172 265 0.016
Human Mouse
negative regulation of signal transduction GO:0009968 206 0.016
positive regulation of purine nucleotide catabolic process GO:0033123 46 0.016
golgi localization GO:0051645 2 0.016
positive regulation of nucleic acid templated transcription GO:1903508 266 0.016
regulation of golgi to plasma membrane protein transport GO:0042996 6 0.016
dorsal ventral pattern formation GO:0009953 133 0.015
anterior posterior pattern specification GO:0009952 136 0.015
purine ribonucleotide catabolic process GO:0009154 109 0.015
regulation of developmental pigmentation GO:0048070 24 0.015
oocyte microtubule cytoskeleton polarization GO:0008103 22 0.015
skin development GO:0043588 65 0.015
wing disc pattern formation GO:0035222 66 0.015
germ line cyst formation GO:0048134 44 0.015
axonogenesis GO:0007409 290 0.015
small gtpase mediated signal transduction GO:0007264 88 0.015
positive regulation of cellular catabolic process GO:0031331 95 0.015
Human Mouse
muscle attachment GO:0016203 36 0.015
response to biotic stimulus GO:0009607 294 0.015
stress activated protein kinase signaling cascade GO:0031098 55 0.015
response to organic cyclic compound GO:0014070 89 0.015
regulation of nurse cell apoptotic process GO:0045477 9 0.015
homeostatic process GO:0042592 199 0.015
regulation of proteolysis GO:0030162 87 0.015
cellular amide metabolic process GO:0043603 80 0.015
adult behavior GO:0030534 137 0.015
neuromuscular synaptic transmission GO:0007274 67 0.015
vesicle fusion GO:0006906 19 0.015
regulation of epidermal cell differentiation GO:0045604 3 0.015
lipid modification GO:0030258 24 0.015
dendrite morphogenesis GO:0048813 199 0.015
regulation of epithelial cell differentiation GO:0030856 4 0.015
positive regulation of exocytosis GO:0045921 4 0.015
regulation of stress activated protein kinase signaling cascade GO:0070302 42 0.015
embryonic pattern specification GO:0009880 174 0.014
regulation of meiosis GO:0040020 3 0.014
memory GO:0007613 94 0.014
connective tissue development GO:0061448 3 0.014
regulation of anatomical structure size GO:0090066 163 0.014
negative regulation of notch signaling pathway GO:0045746 41 0.014
positive regulation of rna biosynthetic process GO:1902680 266 0.014
regulation of cellular catabolic process GO:0031329 157 0.014
Human Mouse
response to external biotic stimulus GO:0043207 293 0.014
intracellular transport GO:0046907 228 0.014
negative regulation of mitotic cell cycle GO:0045930 109 0.014
positive regulation of multicellular organismal process GO:0051240 143 0.014
cell cycle checkpoint GO:0000075 95 0.014
signal transduction by phosphorylation GO:0023014 107 0.014
regulation of transcription from rna polymerase ii promoter GO:0006357 378 0.014
Human Mouse
regulation of neurogenesis GO:0050767 158 0.014
protein localization to organelle GO:0033365 82 0.014
transforming growth factor beta receptor signaling pathway GO:0007179 16 0.014
positive regulation of nucleotide catabolic process GO:0030813 46 0.014
positive regulation of cell death GO:0010942 69 0.014
initiation of dorsal closure GO:0007392 12 0.014
reproductive behavior GO:0019098 122 0.014
lipopolysaccharide mediated signaling pathway GO:0031663 1 0.014
positive regulation of nucleobase containing compound metabolic process GO:0045935 332 0.014
Human Mouse
positive regulation of phosphorylation GO:0042327 87 0.014
negative regulation of nucleic acid templated transcription GO:1903507 240 0.013
Human Mouse
hair cell differentiation GO:0035315 47 0.013
regulation of intracellular transport GO:0032386 64 0.013
regulation of synapse structure and activity GO:0050803 128 0.013
organic hydroxy compound metabolic process GO:1901615 83 0.013
g1 s transition of mitotic cell cycle GO:0000082 31 0.013
mitotic cell cycle checkpoint GO:0007093 88 0.013
epidermal cell differentiation GO:0009913 51 0.013
response to copper ion GO:0046688 4 0.013
negative regulation of gene expression GO:0010629 387 0.013
skeletal muscle fiber development GO:0048741 3 0.013
jnk cascade GO:0007254 50 0.013
establishment of localization in cell GO:0051649 402 0.013
apoptotic process GO:0006915 159 0.013
signal transduction in response to dna damage GO:0042770 3 0.013
epithelial cell differentiation GO:0030855 322 0.013
digestive system development GO:0055123 149 0.013
heart development GO:0007507 82 0.012
embryonic morphogenesis GO:0048598 206 0.012
response to monosaccharide GO:0034284 4 0.012
negative regulation of cell development GO:0010721 62 0.012
glutamate secretion GO:0014047 1 0.012
detection of external stimulus GO:0009581 66 0.012
dendrite self avoidance GO:0070593 8 0.012
macromolecule catabolic process GO:0009057 161 0.012
Human Mouse
positive regulation of cellular component biogenesis GO:0044089 80 0.012
protein import into nucleus GO:0006606 51 0.012
brain development GO:0007420 120 0.012
positive regulation of purine nucleotide metabolic process GO:1900544 55 0.012
anatomical structure homeostasis GO:0060249 97 0.012
pole plasm rna localization GO:0007316 52 0.012
positive regulation of macroautophagy GO:0016239 8 0.012
adult chitin containing cuticle pigmentation GO:0048085 16 0.012
positive regulation of multi organism process GO:0043902 40 0.012
cation transport GO:0006812 110 0.012
renal tubule development GO:0061326 64 0.012
localization of cell GO:0051674 257 0.012
golgi to plasma membrane transport GO:0006893 8 0.012
response to organonitrogen compound GO:0010243 75 0.012
nuclear division GO:0000280 332 0.012
chromatin modification GO:0016568 147 0.012
regulation of cytoskeleton organization GO:0051493 89 0.012
regulation of endocytosis GO:0030100 37 0.011
positive regulation of apoptotic process GO:0043065 47 0.011
regulation of embryonic pattern specification GO:1902875 27 0.011
g2 m transition of mitotic cell cycle GO:0000086 19 0.011
response to radiation GO:0009314 155 0.011
cell cell signaling involved in cell fate commitment GO:0045168 210 0.011
positive regulation of cellular protein metabolic process GO:0032270 118 0.011
proteolysis GO:0006508 192 0.011
regulation of protein transport GO:0051223 57 0.011
striated muscle cell differentiation GO:0051146 90 0.011
positive regulation of hydrolase activity GO:0051345 78 0.011
oocyte anterior posterior axis specification GO:0007314 72 0.011
mitotic spindle elongation GO:0000022 81 0.011
positive regulation of transcription dna templated GO:0045893 266 0.011
positive regulation of secretion by cell GO:1903532 20 0.011
ribonucleoprotein complex biogenesis GO:0022613 31 0.011
leg disc development GO:0035218 92 0.011
retina development in camera type eye GO:0060041 4 0.011
establishment or maintenance of cytoskeleton polarity GO:0030952 44 0.011
regulation of neurotransmitter levels GO:0001505 38 0.011
sensory perception of mechanical stimulus GO:0050954 72 0.011
protein acetylation GO:0006473 39 0.011
developmental maturation GO:0021700 172 0.011
cellular macromolecule catabolic process GO:0044265 136 0.011
Human Mouse
intracellular mrna localization involved in anterior posterior axis specification GO:0060811 53 0.011
myotube cell development GO:0014904 3 0.011
regulation of rho gtpase activity GO:0032319 20 0.011
regulation of cellular ketone metabolic process GO:0010565 3 0.011
positive regulation of protein metabolic process GO:0051247 128 0.011
chromosome segregation GO:0007059 157 0.011
negative regulation of biosynthetic process GO:0009890 277 0.011
Human Mouse
response to nitrogen compound GO:1901698 90 0.011
detection of light stimulus GO:0009583 58 0.011
chemotaxis GO:0006935 249 0.011
negative regulation of developmental growth GO:0048640 64 0.010
blastoderm segmentation GO:0007350 159 0.010
regulation of stress activated mapk cascade GO:0032872 41 0.010
cell fate determination involved in pattern specification GO:0060582 19 0.010
cellular response to oxygen containing compound GO:1901701 79 0.010
regulation of lipid kinase activity GO:0043550 2 0.010
larval development GO:0002164 104 0.010
epithelial tube morphogenesis GO:0060562 88 0.010
antennal development GO:0007469 25 0.010
establishment of rna localization GO:0051236 47 0.010
peptidyl amino acid modification GO:0018193 105 0.010
negative regulation of cell differentiation GO:0045596 143 0.010
Mouse
meiotic chromosome segregation GO:0045132 59 0.010
cellular response to nutrient levels GO:0031669 62 0.010
multicellular organismal aging GO:0010259 140 0.010
positive regulation of nucleoside metabolic process GO:0045979 47 0.010
tissue morphogenesis GO:0048729 297 0.010
imaginal disc derived leg morphogenesis GO:0007480 80 0.010
one carbon metabolic process GO:0006730 3 0.010
regulation of cellular amino acid metabolic process GO:0006521 0 0.010
polyol biosynthetic process GO:0046173 3 0.010
negative regulation of cell death GO:0060548 81 0.010
lipid phosphorylation GO:0046834 11 0.010
learning or memory GO:0007611 141 0.010

Tis11 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in fly and predicted with the fly functional network.

Disease DO term ID Size Probability Func Analog Org
disease of anatomical entity DOID:7 0 0.021
musculoskeletal system disease DOID:17 0 0.021
disease of metabolism DOID:0014667 0 0.019
vascular disease DOID:178 0 0.017
cardiovascular system disease DOID:1287 0 0.017
nervous system disease DOID:863 0 0.014
muscular disease DOID:0080000 0 0.013
muscle tissue disease DOID:66 0 0.013
artery disease DOID:0050828 0 0.011
sensory system disease DOID:0050155 0 0.011
eye and adnexa disease DOID:1492 0 0.010