Drosophila melanogaster

134 known processes

gro (Dmel_CG8384)

groucho

(Aliases: anon-WO0118547.385,m10,DGro,GRO,Gro,E(spl)-WD,BcDNA:LD33829,Grg/TLE,BcDNA.LD33829,E(spl)gro,m9,E(spl)m9/m10,dAES2,BEST:GM01575,dAES1,E(spl)[2],CG8384,l(3)gro,En-spl,m9/10,m9/m10,m9-m10,Dmel\CG8384,dGro,BEST:LD15161)

gro biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
negative regulation of rna metabolic process GO:0051253 251 1.000
negative regulation of nucleobase containing compound metabolic process GO:0045934 261 0.997
cell proliferation GO:0008283 299 0.995
negative regulation of developmental process GO:0051093 201 0.995
positive regulation of biosynthetic process GO:0009891 316 0.993
positive regulation of transcription dna templated GO:0045893 266 0.990
positive regulation of macromolecule metabolic process GO:0010604 405 0.980
Human
stem cell maintenance GO:0019827 67 0.972
positive regulation of macromolecule biosynthetic process GO:0010557 283 0.970
muscle structure development GO:0061061 224 0.969
negative regulation of cellular macromolecule biosynthetic process GO:2000113 267 0.968
positive regulation of nitrogen compound metabolic process GO:0051173 354 0.961
negative regulation of cell cycle GO:0045786 116 0.961
regulation of cell differentiation GO:0045595 302 0.960
Worm
negative regulation of nucleic acid templated transcription GO:1903507 240 0.958
muscle organ development GO:0007517 127 0.954
negative regulation of transcription dna templated GO:0045892 237 0.947
dendrite morphogenesis GO:0048813 199 0.943
positive regulation of rna metabolic process GO:0051254 271 0.940
negative regulation of biosynthetic process GO:0009890 277 0.933
negative regulation of nitrogen compound metabolic process GO:0051172 265 0.932
protein modification process GO:0036211 438 0.930
positive regulation of cellular biosynthetic process GO:0031328 316 0.925
positive regulation of nucleic acid templated transcription GO:1903508 266 0.918
regulation of cell proliferation GO:0042127 163 0.910
negative regulation of mitotic cell cycle GO:0045930 109 0.907
stem cell differentiation GO:0048863 117 0.903
regulation of cell development GO:0060284 215 0.896
Worm
chromatin modification GO:0016568 147 0.878
male gamete generation GO:0048232 201 0.869
negative regulation of cell cycle process GO:0010948 109 0.851
negative regulation of gene expression GO:0010629 387 0.847
stem cell proliferation GO:0072089 88 0.838
endodermal cell differentiation GO:0035987 3 0.835
histone modification GO:0016570 106 0.834
protein modification by small protein conjugation or removal GO:0070647 106 0.829
spermatogenesis GO:0007283 200 0.829
negative regulation of cellular biosynthetic process GO:0031327 277 0.828
regulation of cell cycle phase transition GO:1901987 130 0.827
imaginal disc derived appendage morphogenesis GO:0035114 395 0.812
negative regulation of macromolecule biosynthetic process GO:0010558 270 0.807
cell division GO:0051301 248 0.796
dna metabolic process GO:0006259 227 0.778
small molecule metabolic process GO:0044281 305 0.774
Zebrafish
regulation of mitotic cell cycle GO:0007346 190 0.764
cell cell signaling involved in cell fate commitment GO:0045168 210 0.756
dendrite development GO:0016358 204 0.753
regulation of neuron differentiation GO:0045664 103 0.734
Worm
negative regulation of cell cycle phase transition GO:1901988 103 0.733
establishment of localization in cell GO:0051649 402 0.724
Worm
sensory organ morphogenesis GO:0090596 260 0.724
positive regulation of nucleobase containing compound metabolic process GO:0045935 332 0.708
negative regulation of cell differentiation GO:0045596 143 0.706
regulation of nervous system development GO:0051960 248 0.693
Worm
regulation of phosphorylation GO:0042325 147 0.689
regulation of multicellular organismal development GO:2000026 414 0.684
Worm
regulation of neuroblast proliferation GO:1902692 34 0.675
positive regulation of response to stimulus GO:0048584 323 0.674
positive regulation of cell proliferation GO:0008284 47 0.668
eye development GO:0001654 323 0.658
negative regulation of cell communication GO:0010648 223 0.646
tube development GO:0035295 244 0.645
cellular protein modification process GO:0006464 438 0.619
neuron projection guidance GO:0097485 241 0.619
tissue morphogenesis GO:0048729 297 0.616
regionalization GO:0003002 416 0.596
post embryonic appendage morphogenesis GO:0035120 385 0.592
body morphogenesis GO:0010171 2 0.591
positive regulation of transcription from rna polymerase ii promoter GO:0045944 204 0.589
organonitrogen compound metabolic process GO:1901564 318 0.575
regulation of protein modification process GO:0031399 112 0.572
positive regulation of rna biosynthetic process GO:1902680 266 0.568
columnar cuboidal epithelial cell differentiation GO:0002065 256 0.558
dna repair GO:0006281 54 0.554
r7 cell differentiation GO:0045466 43 0.553
positive regulation of cell death GO:0010942 69 0.550
positive regulation of gene expression GO:0010628 290 0.546
Human
connective tissue development GO:0061448 3 0.541
axon guidance GO:0007411 233 0.538
regulation of transcription from rna polymerase ii promoter GO:0006357 378 0.538
cell fate specification GO:0001708 71 0.537
cellular macromolecule localization GO:0070727 220 0.537
cell death GO:0008219 279 0.534
Human
positive regulation of nervous system development GO:0051962 69 0.533
negative regulation of transcription from rna polymerase ii promoter GO:0000122 119 0.529
neuroblast proliferation GO:0007405 74 0.525
regulation of cell cycle GO:0051726 291 0.523
forebrain development GO:0030900 2 0.521
protein ubiquitination GO:0016567 70 0.518
negative regulation of signaling GO:0023057 219 0.509
protein localization GO:0008104 284 0.508
regulation of protein metabolic process GO:0051246 256 0.501
organelle fission GO:0048285 340 0.494
regulation of stem cell proliferation GO:0072091 40 0.493
multi organism reproductive behavior GO:0044705 121 0.481
regulation of cell cycle process GO:0010564 181 0.481
circulatory system development GO:0072359 82 0.480
regulation of transport GO:0051049 181 0.480
protein complex assembly GO:0006461 200 0.466
regulation of cellular protein metabolic process GO:0032268 243 0.461
appendage morphogenesis GO:0035107 397 0.461
notch signaling pathway GO:0007219 120 0.457
ectodermal placode formation GO:0060788 4 0.450
morphogenesis of an epithelium GO:0002009 276 0.448
wing disc morphogenesis GO:0007472 344 0.432
regulation of intracellular protein transport GO:0033157 46 0.424
camera type eye development GO:0043010 4 0.410
central nervous system development GO:0007417 201 0.376
positive regulation of multicellular organismal process GO:0051240 143 0.375
appendage development GO:0048736 401 0.372
imaginal disc derived wing vein morphogenesis GO:0008586 44 0.368
single organism behavior GO:0044708 391 0.353
apoptotic process GO:0006915 159 0.350
Human
positive regulation of transmembrane receptor protein serine threonine kinase signaling pathway GO:0090100 9 0.348
imaginal disc derived appendage development GO:0048737 399 0.345
eye morphogenesis GO:0048592 260 0.344
transmembrane receptor protein serine threonine kinase signaling pathway GO:0007178 65 0.338
positive regulation of protein metabolic process GO:0051247 128 0.337
regulation of cell death GO:0010941 173 0.328
Human
multicellular organismal reproductive behavior GO:0033057 110 0.325
negative regulation of wnt signaling pathway GO:0030178 28 0.320
digestive system development GO:0055123 149 0.316
heart morphogenesis GO:0003007 32 0.315
regulation of mitotic cell cycle phase transition GO:1901990 130 0.313
somatic stem cell maintenance GO:0035019 14 0.312
regulation of bmp signaling pathway GO:0030510 23 0.311
meiotic nuclear division GO:0007126 151 0.309
chromosome organization GO:0051276 360 0.307
retina development in camera type eye GO:0060041 4 0.307
localization of cell GO:0051674 257 0.306
negative regulation of mitotic cell cycle phase transition GO:1901991 103 0.303
regulation of molecular function GO:0065009 217 0.297
endodermal cell fate commitment GO:0001711 3 0.297
cellular response to dna damage stimulus GO:0006974 223 0.282
negative regulation of response to stimulus GO:0048585 258 0.280
bmp signaling pathway GO:0030509 27 0.280
negative regulation of neurogenesis GO:0050768 53 0.260
digestive tract development GO:0048565 149 0.256
imaginal disc derived wing margin morphogenesis GO:0008587 41 0.255
nuclear transport GO:0051169 72 0.247
positive regulation of developmental process GO:0051094 143 0.247
developmental growth GO:0048589 280 0.245
neural precursor cell proliferation GO:0061351 75 0.242
regulation of notch signaling pathway GO:0008593 100 0.238
embryonic morphogenesis GO:0048598 206 0.236
imaginal disc derived wing vein specification GO:0007474 48 0.233
response to organic substance GO:0010033 284 0.233
retinal ganglion cell axon guidance GO:0031290 12 0.228
regulation of gene expression epigenetic GO:0040029 128 0.216
negative regulation of signal transduction GO:0009968 206 0.214
cell fate determination GO:0001709 91 0.214
regulation of heart morphogenesis GO:2000826 3 0.214
negative regulation of cell development GO:0010721 62 0.209
positive regulation of cell development GO:0010720 61 0.203
peptidyl amino acid modification GO:0018193 105 0.203
camera type eye morphogenesis GO:0048593 2 0.202
stem cell development GO:0048864 79 0.193
transcription from rna polymerase ii promoter GO:0006366 368 0.191
regulation of organelle organization GO:0033043 196 0.184
ribonucleoside monophosphate metabolic process GO:0009161 51 0.183
regulation of dna metabolic process GO:0051052 34 0.177
regulation of neural precursor cell proliferation GO:2000177 35 0.175
regulation of localization GO:0032879 275 0.174
skeletal muscle organ development GO:0060538 48 0.166
enzyme linked receptor protein signaling pathway GO:0007167 179 0.165
regulation of stem cell differentiation GO:2000736 14 0.164
heart development GO:0007507 82 0.163
regulation of transmembrane receptor protein serine threonine kinase signaling pathway GO:0090092 38 0.161
peripheral nervous system development GO:0007422 52 0.159
anatomical structure homeostasis GO:0060249 97 0.158
cell motility GO:0048870 251 0.154
death GO:0016265 284 0.147
Human
compound eye development GO:0048749 307 0.147
positive regulation of protein modification process GO:0031401 58 0.145
positive regulation of cell differentiation GO:0045597 64 0.144
positive regulation of bmp signaling pathway GO:0030513 5 0.143
regulation of organ formation GO:0003156 3 0.142
covalent chromatin modification GO:0016569 106 0.142
embryonic organ development GO:0048568 50 0.140
positive regulation of signal transduction GO:0009967 223 0.135
negative regulation of cellular metabolic process GO:0031324 382 0.134
regulation of cellular localization GO:0060341 136 0.133
protein localization to nucleus GO:0034504 55 0.132
response to endogenous stimulus GO:0009719 119 0.126
gonad development GO:0008406 50 0.126
Worm
negative regulation of nervous system development GO:0051961 92 0.125
immune system process GO:0002376 347 0.124
Zebrafish
wing disc pattern formation GO:0035222 66 0.123
muscle tissue development GO:0060537 30 0.123
nephron tubule morphogenesis GO:0072078 3 0.121
epithelial cell development GO:0002064 274 0.120
spinal cord development GO:0021510 1 0.120
regulation of cellular amino acid metabolic process GO:0006521 0 0.120
transforming growth factor beta receptor signaling pathway GO:0007179 16 0.120
neuron fate commitment GO:0048663 50 0.117
positive regulation of neuron differentiation GO:0045666 26 0.117
hindbrain development GO:0030902 2 0.115
myotube differentiation GO:0014902 46 0.115
nucleus organization GO:0006997 45 0.113
nephron epithelium morphogenesis GO:0072088 3 0.113
genitalia development GO:0048806 26 0.111
Worm
regulation of phosphorus metabolic process GO:0051174 210 0.109
axon development GO:0061564 297 0.108
Worm
intrinsic apoptotic signaling pathway in response to dna damage GO:0008630 11 0.108
wnt signaling pathway GO:0016055 98 0.108
regulation of response to stress GO:0080134 200 0.107
positive regulation of cellular protein metabolic process GO:0032270 118 0.105
organic substance transport GO:0071702 257 0.104
regulation of transforming growth factor beta receptor signaling pathway GO:0017015 6 0.104
mrna metabolic process GO:0016071 124 0.104
negative regulation of multicellular organismal process GO:0051241 142 0.103
cellular protein localization GO:0034613 160 0.103
taxis GO:0042330 304 0.103
positive regulation of apoptotic process GO:0043065 47 0.103
cytoplasmic microtubule organization GO:0031122 22 0.102
epithelial cell differentiation GO:0030855 322 0.099
mesoderm development GO:0007498 78 0.096
regulation of g1 s transition of mitotic cell cycle GO:2000045 23 0.092
regulation of protein transport GO:0051223 57 0.092
positive regulation of cell communication GO:0010647 250 0.089
amine metabolic process GO:0009308 12 0.089
epidermis development GO:0008544 65 0.088
mesenchymal cell differentiation GO:0048762 1 0.084
endocytosis GO:0006897 310 0.084
imaginal disc growth GO:0007446 37 0.083
nephron tubule development GO:0072080 3 0.081
sister chromatid segregation GO:0000819 92 0.081
retina morphogenesis in camera type eye GO:0060042 2 0.081
protein transport GO:0015031 155 0.079
regulation of neurogenesis GO:0050767 158 0.077
Worm
head development GO:0060322 135 0.077
imaginal disc derived wing morphogenesis GO:0007476 337 0.076
kidney development GO:0001822 3 0.075
protein complex biogenesis GO:0070271 201 0.074
cellular amine metabolic process GO:0044106 12 0.074
cell cycle checkpoint GO:0000075 95 0.074
embryonic organ morphogenesis GO:0048562 5 0.074
cellular response to chemical stimulus GO:0070887 199 0.073
chromatin remodeling GO:0006338 72 0.073
negative regulation of rna biosynthetic process GO:1902679 240 0.072
proteolysis GO:0006508 192 0.071
mitotic dna integrity checkpoint GO:0044774 75 0.071
nephron epithelium development GO:0072009 3 0.069
reproductive system development GO:0061458 74 0.068
Worm
positive regulation of protein import into nucleus translocation GO:0033160 2 0.068
protein modification by small protein conjugation GO:0032446 79 0.068
regulation of cell projection organization GO:0031344 92 0.068
Worm
intracellular protein transport GO:0006886 104 0.068
cell type specific apoptotic process GO:0097285 38 0.067
defense response GO:0006952 300 0.066
cardiovascular system development GO:0072358 82 0.066
eye antennal disc development GO:0035214 60 0.065
mushroom body development GO:0016319 70 0.064
negative regulation of neural precursor cell proliferation GO:2000178 27 0.064
growth GO:0040007 359 0.063
mitotic cell cycle checkpoint GO:0007093 88 0.061
single organism catabolic process GO:0044712 228 0.061
sex differentiation GO:0007548 81 0.061
Worm
positive regulation of cellular component organization GO:0051130 156 0.060
protein targeting GO:0006605 64 0.060
nucleoside triphosphate metabolic process GO:0009141 120 0.059
anterior posterior pattern specification GO:0009952 136 0.059
response to organic cyclic compound GO:0014070 89 0.059
negative regulation of transforming growth factor beta receptor signaling pathway GO:0030512 4 0.059
sex determination GO:0007530 18 0.059
mitotic cell cycle phase transition GO:0044772 138 0.058
morphogenesis of embryonic epithelium GO:0016331 94 0.058
regulation of protein localization GO:0032880 76 0.057
positive regulation of stem cell differentiation GO:2000738 3 0.057
positive regulation of cellular amino acid metabolic process GO:0045764 0 0.056
protein import into nucleus GO:0006606 51 0.055
embryo development ending in birth or egg hatching GO:0009792 152 0.055
Worm
dna methylation or demethylation GO:0044728 4 0.055
phosphorylation GO:0016310 294 0.055
carbohydrate derivative metabolic process GO:1901135 217 0.055
gastrulation GO:0007369 70 0.054
organic substance catabolic process GO:1901575 308 0.054
mesenchymal cell development GO:0014031 1 0.053
regulation of programmed cell death GO:0043067 152 0.053
Human
neuroblast division GO:0055057 35 0.052
positive regulation of molecular function GO:0044093 136 0.052
neurological system process GO:0050877 358 0.052
organ growth GO:0035265 56 0.052
positive regulation of signaling GO:0023056 243 0.051
regulation of neuron projection development GO:0010975 69 0.050
Worm
formation of primary germ layer GO:0001704 24 0.048
negative regulation of notch signaling pathway GO:0045746 41 0.048
positive regulation of neurogenesis GO:0050769 41 0.047
axis specification GO:0009798 167 0.047
stress granule disassembly GO:0035617 1 0.047
muscle cell differentiation GO:0042692 103 0.047
gliogenesis GO:0042063 80 0.046
regulation of immune system process GO:0002682 176 0.045
regulation of hematopoietic progenitor cell differentiation GO:1901532 1 0.044
regulation of chromosome organization GO:0033044 64 0.043
blastoderm segmentation GO:0007350 159 0.042
cellular amino acid metabolic process GO:0006520 61 0.041
central nervous system neuron differentiation GO:0021953 8 0.041
regulation of glial cell differentiation GO:0045685 1 0.040
nuclear import GO:0051170 51 0.040
negative regulation of cell proliferation GO:0008285 69 0.040
cell migration GO:0016477 238 0.040
reproductive structure development GO:0048608 74 0.040
Worm
smoothened signaling pathway GO:0007224 49 0.039
meiotic cell cycle process GO:1903046 132 0.039
tube morphogenesis GO:0035239 191 0.038
chromatin organization GO:0006325 207 0.038
regulation of phosphate metabolic process GO:0019220 210 0.038
regulation of dendrite morphogenesis GO:0048814 28 0.038
negative regulation of molecular function GO:0044092 51 0.037
telencephalon development GO:0021537 2 0.037
chromosome segregation GO:0007059 157 0.037
regulation of tyrosine phosphorylation of stat protein GO:0042509 1 0.037
neuron recognition GO:0008038 101 0.037
regulation of imaginal disc growth GO:0045570 26 0.036
establishment of protein localization GO:0045184 163 0.036
regulation of apoptotic process GO:0042981 130 0.036
Human
regulation of transferase activity GO:0051338 58 0.036
secretion GO:0046903 109 0.035
negative regulation of phosphatase activity GO:0010923 3 0.035
mitotic nuclear division GO:0007067 213 0.035
asymmetric cell division GO:0008356 37 0.035
spermatid differentiation GO:0048515 114 0.035
cell cycle phase transition GO:0044770 140 0.034
ribonucleoside triphosphate catabolic process GO:0009203 108 0.034
regulation of cellular response to stress GO:0080135 89 0.033
muscle cell fate commitment GO:0042693 14 0.033
regulation of cell morphogenesis GO:0022604 163 0.033
Worm
nucleocytoplasmic transport GO:0006913 72 0.032
skeletal muscle tissue development GO:0007519 13 0.032
mitotic spindle organization GO:0007052 220 0.032
myoblast fusion GO:0007520 43 0.031
oocyte morphogenesis GO:0048601 3 0.031
striated muscle tissue development GO:0014706 27 0.031
intracellular transport GO:0046907 228 0.031
intracellular signal transduction GO:0035556 300 0.030
Human
digestive tract morphogenesis GO:0048546 127 0.030
equator specification GO:0045317 4 0.030
signal transduction downstream of smoothened GO:0007227 5 0.030
locomotory behavior GO:0007626 176 0.030
activation of jun kinase activity GO:0007257 3 0.029
nephron development GO:0072006 3 0.029
g1 s transition of mitotic cell cycle GO:0000082 31 0.029
negative regulation of transmembrane receptor protein serine threonine kinase signaling pathway GO:0090101 18 0.029
glial cell differentiation GO:0010001 35 0.028
dna alkylation GO:0006305 4 0.028
regulation of wnt signaling pathway GO:0030111 68 0.028
regulation of phosphatase activity GO:0010921 3 0.027
nuclear division GO:0000280 332 0.027
eggshell chorion assembly GO:0007306 66 0.027
kidney epithelium development GO:0072073 3 0.027
regulation of kinase activity GO:0043549 53 0.027
vesicle mediated transport GO:0016192 381 0.027
axonogenesis GO:0007409 290 0.026
Worm
negative regulation of cell cycle g1 s phase transition GO:1902807 13 0.026
neural retina development GO:0003407 4 0.026
purine ribonucleoside monophosphate metabolic process GO:0009167 50 0.026
protein targeting to nucleus GO:0044744 51 0.026
negative regulation of programmed cell death GO:0043069 72 0.025
Human
open tracheal system development GO:0007424 204 0.025
phagocytosis GO:0006909 215 0.025
response to wounding GO:0009611 94 0.025
hematopoietic progenitor cell differentiation GO:0002244 1 0.025
establishment of spindle localization GO:0051293 22 0.025
positive regulation of transport GO:0051050 92 0.025
mrna processing GO:0006397 104 0.025
regulation of anatomical structure morphogenesis GO:0022603 242 0.025
Worm
developmental maturation GO:0021700 172 0.025
aging GO:0007568 143 0.024
ectodermal placode development GO:0071696 4 0.024
cellular component assembly involved in morphogenesis GO:0010927 151 0.024
regulation of cyclin dependent protein serine threonine kinase activity GO:0000079 3 0.024
positive regulation of notch signaling pathway GO:0045747 34 0.024
midgut development GO:0007494 23 0.024
regulation of cellular amine metabolic process GO:0033238 3 0.024
meiotic cell cycle GO:0051321 171 0.024
brain development GO:0007420 120 0.024
intrinsic apoptotic signaling pathway GO:0097193 16 0.023
regulation of neuron death GO:1901214 26 0.023
regulation of establishment of protein localization GO:0070201 61 0.023
cellular response to organic substance GO:0071310 132 0.023
dorsal ventral pattern formation GO:0009953 133 0.023
adult behavior GO:0030534 137 0.023
meiotic nuclear envelope disassembly GO:0051078 2 0.023
kidney morphogenesis GO:0060993 3 0.023
mitotic dna damage checkpoint GO:0044773 74 0.023
regulation of atp catabolic process GO:1903289 4 0.022
establishment of tissue polarity GO:0007164 87 0.022
mitotic g2 dna damage checkpoint GO:0007095 69 0.022
positive regulation of cell cycle GO:0045787 43 0.022
cellular protein complex assembly GO:0043623 71 0.021
hemopoiesis GO:0030097 46 0.021
Zebrafish
establishment of mitotic spindle localization GO:0040001 17 0.021
regulation of cell cycle g1 s phase transition GO:1902806 23 0.021
photoreceptor cell fate commitment GO:0046552 41 0.021
regulation of epithelial cell differentiation GO:0030856 4 0.021
positive regulation of developmental growth GO:0048639 62 0.020
determination of dorsal ventral asymmetry GO:0048262 3 0.020
response to abiotic stimulus GO:0009628 341 0.020
dendrite regeneration GO:0031104 2 0.020
developmental programmed cell death GO:0010623 138 0.020
regulation of protein serine threonine kinase activity GO:0071900 25 0.020
anterior head segmentation GO:0035288 3 0.020
single organism nuclear import GO:1902593 51 0.019
pigment cell differentiation GO:0050931 3 0.019
regulation of cell proliferation involved in compound eye morphogenesis GO:2000495 2 0.019
ribonucleoprotein complex disassembly GO:0032988 1 0.019
regulation of intracellular transport GO:0032386 64 0.019
actin filament organization GO:0007015 126 0.019
epithelial tube morphogenesis GO:0060562 88 0.019
cytoplasmic transport GO:0016482 130 0.019
positive regulation of cell maturation GO:1903431 2 0.019
single organism cellular localization GO:1902580 180 0.019
unsaturated fatty acid biosynthetic process GO:0006636 1 0.019
cell cycle arrest GO:0007050 4 0.018
immune response GO:0006955 246 0.018
imaginal disc pattern formation GO:0007447 91 0.018
maternal determination of dorsal ventral axis ovarian follicular epithelium soma encoded GO:0008071 1 0.018
regulation of hydrolase activity GO:0051336 97 0.018
signal transduction by phosphorylation GO:0023014 107 0.017
compound eye morphogenesis GO:0001745 249 0.017
carboxylic acid metabolic process GO:0019752 92 0.017
Zebrafish
oocyte fate commitment GO:0048600 2 0.017
single organism intracellular transport GO:1902582 207 0.017
cellular ketone metabolic process GO:0042180 24 0.017
Zebrafish
dorsal ventral axis specification GO:0009950 66 0.017
germ line stem cell maintenance GO:0030718 50 0.017
regulation of catabolic process GO:0009894 170 0.017
regulation of organ morphogenesis GO:2000027 78 0.017
negative regulation of neuron differentiation GO:0045665 16 0.017
mrna splicing via spliceosome GO:0000398 73 0.017
meiotic spindle checkpoint GO:0044779 1 0.017
rac protein signal transduction GO:0016601 3 0.017
positive regulation of neural precursor cell proliferation GO:2000179 8 0.017
epithelial cell migration GO:0010631 148 0.016
small gtpase mediated signal transduction GO:0007264 88 0.016
multicellular organism growth GO:0035264 46 0.016
glial cell fate commitment GO:0021781 3 0.016
negative regulation of intrinsic apoptotic signaling pathway GO:2001243 1 0.016
catabolic process GO:0009056 409 0.016
cell fate commitment involved in pattern specification GO:0060581 31 0.016
positive regulation of chromatin silencing at telomere GO:0031940 2 0.016
regulation of planar cell polarity pathway involved in axis elongation GO:2000040 2 0.016
ribose phosphate metabolic process GO:0019693 145 0.015
regulation of cellular catabolic process GO:0031329 157 0.015
larval development GO:0002164 104 0.015
Worm
spinal cord dorsal ventral patterning GO:0021513 1 0.015
protein phosphorylation GO:0006468 169 0.015
regulation of sequence specific dna binding transcription factor activity GO:0051090 12 0.015
columnar cuboidal epithelial cell development GO:0002066 249 0.015
regulation of cellular ketone metabolic process GO:0010565 3 0.015
Zebrafish
anterior posterior pattern specification imaginal disc GO:0007448 16 0.015
regulation of catalytic activity GO:0050790 185 0.015
negative regulation of smoothened signaling pathway GO:0045879 16 0.015
activation of ral gtpase activity GO:0032859 1 0.015
nucleoside metabolic process GO:0009116 127 0.015
neuronal stem cell maintenance GO:0097150 4 0.014
r3 r4 cell fate commitment GO:0007464 10 0.014
regulation of dendrite development GO:0050773 37 0.014
regulation of nucleocytoplasmic transport GO:0046822 35 0.014
positive regulation of golgi to plasma membrane protein transport GO:0042998 2 0.014
cardiocyte differentiation GO:0035051 29 0.014
hindgut morphogenesis GO:0007442 58 0.014
programmed cell death GO:0012501 257 0.014
Human
sensory neuron axon guidance GO:0097374 2 0.014
positive regulation of endopeptidase activity GO:0010950 26 0.014
wing disc dorsal ventral pattern formation GO:0048190 47 0.014
renal system development GO:0072001 72 0.013
r1 r6 cell differentiation GO:0048052 4 0.013
epidermis morphogenesis GO:0048730 5 0.013
neuronal stem cell division GO:0036445 35 0.013
regulation of dna templated transcription elongation GO:0032784 17 0.013
microtubule sliding GO:0051012 3 0.013
regulation of hematopoietic stem cell differentiation GO:1902036 1 0.013
organelle inheritance GO:0048308 2 0.013
cell cycle g1 s phase transition GO:0044843 31 0.013
regulation of mrna splicing via spliceosome GO:0048024 64 0.013
cellular response to endogenous stimulus GO:0071495 80 0.013
muscle cell fate specification GO:0042694 7 0.013
negative regulation of immune system process GO:0002683 50 0.013
regulation of protein modification by small protein conjugation or removal GO:1903320 25 0.013
regulation of cell fate commitment GO:0010453 29 0.013
organic acid metabolic process GO:0006082 103 0.012
Zebrafish
positive regulation of catalytic activity GO:0043085 118 0.012
macromolecule deacylation GO:0098732 11 0.012
regulation of chromatin modification GO:1903308 28 0.012
regulation of jak stat cascade GO:0046425 43 0.012
positive regulation of neuroblast proliferation GO:0002052 7 0.012
posttranscriptional gene silencing by rna GO:0035194 45 0.012

gro disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in fly and predicted with the fly functional network.

Disease DO term ID Size Probability Func Analog Org
disease of anatomical entity DOID:7 0 0.122
musculoskeletal system disease DOID:17 0 0.110
cancer DOID:162 0 0.073
disease of cellular proliferation DOID:14566 0 0.073
organ system cancer DOID:0050686 0 0.073
bone disease DOID:0080001 0 0.019
connective tissue disease DOID:65 0 0.019
head and neck cancer DOID:11934 0 0.012
nervous system disease DOID:863 0 0.012