Drosophila melanogaster

100 known processes

egr (Dmel_CG12919)

eiger

(Aliases: Regg1,Ect1,BcDNA:RH51659,Egr,darth,regg1,dt1,Dmel\CG12919,CG12919)

egr biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
defense response GO:0006952 300 0.857
defense response to other organism GO:0098542 225 0.800
intracellular signal transduction GO:0035556 300 0.764
immune effector process GO:0002252 98 0.743
Mouse
regulation of defense response GO:0031347 102 0.635
Mouse
cellular catabolic process GO:0044248 372 0.618
cellular response to extracellular stimulus GO:0031668 64 0.566
cell death GO:0008219 279 0.558
regulation of transmembrane transport GO:0034762 27 0.555
circadian rhythm GO:0007623 105 0.553
defense response to bacterium GO:0042742 178 0.552
regulation of synapse structure and activity GO:0050803 128 0.539
immune system process GO:0002376 347 0.534
regulation of cell differentiation GO:0045595 302 0.523
Mouse
cellular response to external stimulus GO:0071496 66 0.520
response to organic substance GO:0010033 284 0.500
Zebrafish Mouse
apoptotic process GO:0006915 159 0.494
regulation of multi organism process GO:0043900 131 0.468
Mouse
regulation of localization GO:0032879 275 0.465
Mouse
enzyme linked receptor protein signaling pathway GO:0007167 179 0.455
post embryonic appendage morphogenesis GO:0035120 385 0.445
negative regulation of signal transduction GO:0009968 206 0.443
developmental growth GO:0048589 280 0.440
developmental programmed cell death GO:0010623 138 0.421
Mouse
chemotaxis GO:0006935 249 0.418
Mouse
regulation of intracellular signal transduction GO:1902531 236 0.416
Human Mouse
neuron projection guidance GO:0097485 241 0.414
negative regulation of response to stimulus GO:0048585 258 0.405
organonitrogen compound metabolic process GO:1901564 318 0.401
small molecule metabolic process GO:0044281 305 0.380
neurological system process GO:0050877 358 0.379
negative regulation of cell communication GO:0010648 223 0.377
negative regulation of signaling GO:0023057 219 0.373
immune response GO:0006955 246 0.364
histolysis GO:0007559 102 0.362
positive regulation of nitrogen compound metabolic process GO:0051173 354 0.360
Mouse
regulation of autophagy GO:0010506 62 0.356
regulation of cell death GO:0010941 173 0.355
Human Zebrafish Mouse
endocytosis GO:0006897 310 0.347
wing disc morphogenesis GO:0007472 344 0.334
hippo signaling GO:0035329 20 0.330
regulation of cellular catabolic process GO:0031329 157 0.330
tissue death GO:0016271 102 0.330
lateral inhibition GO:0046331 206 0.324
regulation of phosphorylation GO:0042325 147 0.321
Mouse
gland development GO:0048732 191 0.318
Zebrafish Mouse
embryonic morphogenesis GO:0048598 206 0.301
positive regulation of signal transduction GO:0009967 223 0.295
Human Zebrafish Mouse
zymogen activation GO:0031638 20 0.291
Human Mouse
gland morphogenesis GO:0022612 145 0.289
Mouse
regulation of catabolic process GO:0009894 170 0.288
synapse organization GO:0050808 196 0.285
regulation of response to stress GO:0080134 200 0.284
Mouse
response to external biotic stimulus GO:0043207 293 0.281
regulation of programmed cell death GO:0043067 152 0.281
Human Zebrafish Mouse
positive regulation of cell death GO:0010942 69 0.269
Human Zebrafish Mouse
innate immune response GO:0045087 144 0.268
response to other organism GO:0051707 293 0.266
production of molecular mediator of immune response GO:0002440 46 0.263
Mouse
purine containing compound metabolic process GO:0072521 155 0.254
appendage morphogenesis GO:0035107 397 0.253
cellular protein localization GO:0034613 160 0.253
Mouse
regulation of wnt signaling pathway GO:0030111 68 0.252
cell motility GO:0048870 251 0.251
Mouse
wnt signaling pathway GO:0016055 98 0.249
imaginal disc derived wing morphogenesis GO:0007476 337 0.243
vesicle mediated transport GO:0016192 381 0.239
response to nitrogen compound GO:1901698 90 0.233
Zebrafish Mouse
axonogenesis GO:0007409 290 0.227
salivary gland morphogenesis GO:0007435 145 0.224
Mouse
carbohydrate metabolic process GO:0005975 82 0.224
Mouse
morphogenesis of an epithelium GO:0002009 276 0.224
Mouse
tube morphogenesis GO:0035239 191 0.223
positive regulation of molecular function GO:0044093 136 0.219
Human Mouse
chemical homeostasis GO:0048878 92 0.217
Mouse
response to alcohol GO:0097305 95 0.217
positive regulation of cell communication GO:0010647 250 0.217
Human Zebrafish Mouse
carbohydrate derivative biosynthetic process GO:1901137 85 0.213
sensory organ morphogenesis GO:0090596 260 0.213
Mouse
negative regulation of cellular biosynthetic process GO:0031327 277 0.209
Human Mouse
organophosphate metabolic process GO:0019637 195 0.206
tube development GO:0035295 244 0.201
nucleobase containing small molecule metabolic process GO:0055086 174 0.201
regulation of response to biotic stimulus GO:0002831 63 0.200
positive regulation of cellular biosynthetic process GO:0031328 316 0.199
Mouse
catabolic process GO:0009056 409 0.199
cellular response to chemical stimulus GO:0070887 199 0.194
Mouse
tissue morphogenesis GO:0048729 297 0.193
Mouse
chromatin modification GO:0016568 147 0.192
positive regulation of protein metabolic process GO:0051247 128 0.188
Human Mouse
response to biotic stimulus GO:0009607 294 0.188
response to organic cyclic compound GO:0014070 89 0.187
Zebrafish
regulation of apoptotic process GO:0042981 130 0.185
Human Zebrafish Mouse
peptide metabolic process GO:0006518 80 0.185
cation transmembrane transport GO:0098655 88 0.182
cellular response to nutrient levels GO:0031669 62 0.181
sensory perception GO:0007600 196 0.180
regulation of response to external stimulus GO:0032101 115 0.173
Mouse
anatomical structure homeostasis GO:0060249 97 0.171
ion transmembrane transport GO:0034220 122 0.168
imaginal disc derived appendage development GO:0048737 399 0.167
taxis GO:0042330 304 0.165
Mouse
signal transduction by phosphorylation GO:0023014 107 0.164
regulation of immune response GO:0050776 118 0.160
Mouse
single organism catabolic process GO:0044712 228 0.155
regulation of synapse organization GO:0050807 110 0.154
cytoplasmic transport GO:0016482 130 0.154
Mouse
ubiquitin dependent protein catabolic process GO:0006511 78 0.151
death GO:0016265 284 0.149
hemocyte differentiation GO:0042386 38 0.147
positive regulation of phosphorus metabolic process GO:0010562 139 0.144
Mouse
carbohydrate derivative metabolic process GO:1901135 217 0.143
negative regulation of nitrogen compound metabolic process GO:0051172 265 0.143
Human Mouse
cellular response to mechanical stimulus GO:0071260 2 0.143
regulation of endopeptidase activity GO:0052548 36 0.142
Human Mouse
regulation of mapk cascade GO:0043408 92 0.142
Mouse
cation transport GO:0006812 110 0.142
cellular protein modification process GO:0006464 438 0.141
Mouse
pigment metabolic process GO:0042440 84 0.141
regulation of humoral immune response GO:0002920 51 0.139
Mouse
humoral immune response GO:0006959 117 0.138
Mouse
regulation of compound eye retinal cell programmed cell death GO:0046669 18 0.137
cellular response to abiotic stimulus GO:0071214 58 0.137
protein localization GO:0008104 284 0.132
positive regulation of signaling GO:0023056 243 0.131
Human Zebrafish Mouse
regulation of growth GO:0040008 233 0.129
Mouse
proteolysis GO:0006508 192 0.129
Human Mouse
mapk cascade GO:0000165 107 0.129
localization of cell GO:0051674 257 0.125
Mouse
purine nucleoside catabolic process GO:0006152 112 0.125
positive regulation of response to stimulus GO:0048584 323 0.121
Human Zebrafish Mouse
regulation of nf kappab import into nucleus GO:0042345 1 0.121
Mouse
regulation of immune system process GO:0002682 176 0.121
Mouse
response to wounding GO:0009611 94 0.121
Mouse
axon development GO:0061564 297 0.119
positive regulation of gene expression GO:0010628 290 0.119
Mouse
regulation of mitotic cell cycle GO:0007346 190 0.118
positive regulation of rna metabolic process GO:0051254 271 0.118
Mouse
response to nutrient levels GO:0031667 114 0.116
negative regulation of growth GO:0045926 84 0.116
Mouse
melanin metabolic process GO:0006582 47 0.116
regulation of stress activated protein kinase signaling cascade GO:0070302 42 0.115
Mouse
erbb signaling pathway GO:0038127 58 0.113
protein acetylation GO:0006473 39 0.113
necrotic cell death GO:0070265 1 0.111
Human Mouse
nucleotide catabolic process GO:0009166 109 0.110
response to extracellular stimulus GO:0009991 116 0.109
compound eye development GO:0048749 307 0.109
regulation of cell cycle process GO:0010564 181 0.109
growth GO:0040007 359 0.109
Mouse
cell cycle phase transition GO:0044770 140 0.109
stress activated mapk cascade GO:0051403 52 0.108
cellular nitrogen compound catabolic process GO:0044270 165 0.108
imaginal disc derived appendage morphogenesis GO:0035114 395 0.107
response to bacterium GO:0009617 198 0.107
cellular response to organic substance GO:0071310 132 0.104
Mouse
regulation of developmental growth GO:0048638 174 0.102
phenol containing compound metabolic process GO:0018958 57 0.102
response to growth factor GO:0070848 31 0.100
lipid metabolic process GO:0006629 121 0.098
regulation of cellular response to stress GO:0080135 89 0.097
Mouse
negative regulation of developmental growth GO:0048640 64 0.096
cellular response to starvation GO:0009267 61 0.096
positive regulation of macromolecule metabolic process GO:0010604 405 0.095
Human Mouse
salivary gland development GO:0007431 162 0.094
Mouse
regulation of system process GO:0044057 36 0.094
jnk cascade GO:0007254 50 0.093
antimicrobial peptide production GO:0002775 46 0.093
regulation of cellular protein metabolic process GO:0032268 243 0.093
Human Mouse
cellular macromolecule localization GO:0070727 220 0.093
Mouse
establishment of localization in cell GO:0051649 402 0.092
Mouse
response to abiotic stimulus GO:0009628 341 0.092
regulation of cellular localization GO:0060341 136 0.092
Mouse
neuromuscular junction development GO:0007528 149 0.091
rhythmic process GO:0048511 106 0.090
stress activated protein kinase signaling cascade GO:0031098 55 0.090
actin mediated cell contraction GO:0070252 21 0.090
regulation of tube size GO:0035150 46 0.089
cell cell signaling involved in cell fate commitment GO:0045168 210 0.088
extrinsic apoptotic signaling pathway GO:0097191 1 0.087
positive regulation of autophagy GO:0010508 21 0.087
protein phosphorylation GO:0006468 169 0.087
Mouse
exocrine system development GO:0035272 162 0.086
Mouse
regulation of anatomical structure size GO:0090066 163 0.085
phagocytosis GO:0006909 215 0.085
single organism cellular localization GO:1902580 180 0.085
Mouse
negative regulation of gene expression GO:0010629 387 0.084
Human Mouse
defense response to gram negative bacterium GO:0050829 94 0.083
regulation of antimicrobial humoral response GO:0002759 50 0.082
compound eye morphogenesis GO:0001745 249 0.082
regulation of innate immune response GO:0045088 71 0.081
kidney development GO:0001822 3 0.080
internal protein amino acid acetylation GO:0006475 38 0.079
phosphorylation GO:0016310 294 0.078
ribose phosphate metabolic process GO:0019693 145 0.078
regulation of proteolysis GO:0030162 87 0.077
Human Mouse
transmembrane transport GO:0055085 139 0.077
establishment of protein localization GO:0045184 163 0.076
Mouse
intracellular transport GO:0046907 228 0.075
Mouse
maintenance of gastrointestinal epithelium GO:0030277 3 0.074
larval development GO:0002164 104 0.074
cellular lipid metabolic process GO:0044255 83 0.074
response to light stimulus GO:0009416 124 0.074
glycosyl compound catabolic process GO:1901658 112 0.074
response to monosaccharide GO:0034284 4 0.074
regulation of molecular function GO:0065009 217 0.073
Human Mouse
regulation of antimicrobial peptide production GO:0002784 44 0.072
inorganic cation transmembrane transport GO:0098662 61 0.072
regulation of phosphorus metabolic process GO:0051174 210 0.072
Mouse
response to radiation GO:0009314 155 0.071
regulation of cellular component biogenesis GO:0044087 201 0.071
regulation of antibacterial peptide production GO:0002786 22 0.071
ventral furrow formation GO:0007370 17 0.070
axon guidance GO:0007411 233 0.069
regulation of protein transport GO:0051223 57 0.069
Mouse
nitrogen compound transport GO:0071705 85 0.069
Mouse
cellular response to endogenous stimulus GO:0071495 80 0.069
Mouse
response to hexose GO:0009746 3 0.068
response to starvation GO:0042594 97 0.068
organic substance transport GO:0071702 257 0.067
Mouse
synapse assembly GO:0007416 143 0.067
purine ribonucleotide metabolic process GO:0009150 145 0.067
proteolysis involved in cellular protein catabolic process GO:0051603 83 0.066
salivary gland cell autophagic cell death GO:0035071 83 0.065
inorganic ion transmembrane transport GO:0098660 73 0.065
regulation of i kappab kinase nf kappab signaling GO:0043122 2 0.065
Human Mouse
negative regulation of apoptotic process GO:0043066 63 0.065
regulation of hemocyte differentiation GO:0045610 22 0.065
epithelial cell differentiation GO:0030855 322 0.064
negative regulation of cellular metabolic process GO:0031324 382 0.064
Human Mouse
transmembrane receptor protein tyrosine kinase signaling pathway GO:0007169 116 0.063
negative regulation of insulin secretion GO:0046676 1 0.063
programmed cell death GO:0012501 257 0.063
chromatin remodeling GO:0006338 72 0.062
cellular amide metabolic process GO:0043603 80 0.062
regulation of phosphatidylinositol 3 kinase activity GO:0043551 2 0.062
cell migration GO:0016477 238 0.062
Mouse
organic substance catabolic process GO:1901575 308 0.061
dna damage checkpoint GO:0000077 78 0.061
ribonucleotide metabolic process GO:0009259 145 0.061
heterocycle catabolic process GO:0046700 166 0.059
single organism behavior GO:0044708 391 0.059
autophagy GO:0006914 108 0.059
cell division GO:0051301 248 0.059
protein complex biogenesis GO:0070271 201 0.059
Mouse
modification dependent protein catabolic process GO:0019941 78 0.059
regulation of jnk cascade GO:0046328 40 0.059
Mouse
response to glucose GO:0009749 2 0.059
regulation of ion transport GO:0043269 39 0.058
Mouse
dna metabolic process GO:0006259 227 0.058
Mouse
positive regulation of multicellular organismal process GO:0051240 143 0.058
Mouse
salivary gland histolysis GO:0035070 88 0.058
locomotor rhythm GO:0045475 56 0.058
secondary metabolic process GO:0019748 75 0.058
purine containing compound catabolic process GO:0072523 112 0.057
regulation of response to wounding GO:1903034 19 0.057
Mouse
appendage development GO:0048736 401 0.057
protein modification process GO:0036211 438 0.057
Mouse
modification dependent macromolecule catabolic process GO:0043632 79 0.055
positive regulation of phosphorylation GO:0042327 87 0.053
Mouse
response to organonitrogen compound GO:0010243 75 0.052
Mouse
nucleotide metabolic process GO:0009117 161 0.052
organophosphate catabolic process GO:0046434 112 0.051
cellular protein catabolic process GO:0044257 83 0.051
response to purine containing compound GO:0014074 12 0.051
negative regulation of cell death GO:0060548 81 0.051
establishment of tissue polarity GO:0007164 87 0.051
posttranscriptional gene silencing GO:0016441 46 0.049
regulation of organelle organization GO:0033043 196 0.049
Human
single organism cell adhesion GO:0098602 47 0.049
ribonucleoside metabolic process GO:0009119 127 0.049
basement membrane organization GO:0071711 10 0.048
antibacterial humoral response GO:0019731 44 0.048
single organismal cell cell adhesion GO:0016337 45 0.048
embryonic development via the syncytial blastoderm GO:0001700 148 0.048
mucosal immune response GO:0002385 10 0.048
response to endogenous stimulus GO:0009719 119 0.048
Mouse
aromatic compound catabolic process GO:0019439 166 0.048
purine nucleoside metabolic process GO:0042278 127 0.047
organic cyclic compound catabolic process GO:1901361 168 0.047
protein catabolic process GO:0030163 101 0.047
actin filament based movement GO:0030048 26 0.047
positive regulation of programmed cell death GO:0043068 62 0.046
Human Zebrafish Mouse
cellular response to dna damage stimulus GO:0006974 223 0.046
Mouse
carbohydrate derivative catabolic process GO:1901136 118 0.046
response to organophosphorus GO:0046683 2 0.045
positive regulation of cell motility GO:2000147 3 0.045
Mouse
cellular amino acid metabolic process GO:0006520 61 0.045
positive regulation of apoptotic process GO:0043065 47 0.045
Human Zebrafish Mouse
autophagic cell death GO:0048102 83 0.044
positive regulation of endopeptidase activity GO:0010950 26 0.044
Human Mouse
decapentaplegic signaling pathway GO:0008101 19 0.044
positive regulation of catalytic activity GO:0043085 118 0.044
Human Mouse
positive regulation of ion transmembrane transporter activity GO:0032414 4 0.044
eye morphogenesis GO:0048592 260 0.044
Mouse
organic acid metabolic process GO:0006082 103 0.044
oxoacid metabolic process GO:0043436 103 0.044
embryo development ending in birth or egg hatching GO:0009792 152 0.043
positive regulation of phosphate metabolic process GO:0045937 139 0.043
Mouse
positive regulation of cellular catabolic process GO:0031331 95 0.043
regulation of cellular amide metabolic process GO:0034248 39 0.043
negative regulation of cell proliferation GO:0008285 69 0.042
columnar cuboidal epithelial cell development GO:0002066 249 0.042
regulation of transport GO:0051049 181 0.042
Mouse
gastrulation with mouth forming first GO:0001703 36 0.042
autophagic vacuole assembly GO:0000045 2 0.042
open tracheal system development GO:0007424 204 0.042
synaptic transmission GO:0007268 288 0.042
nucleoside phosphate metabolic process GO:0006753 162 0.041
positive regulation of biosynthetic process GO:0009891 316 0.041
Mouse
posttranscriptional regulation of gene expression GO:0010608 145 0.041
Mouse
protein import into nucleus GO:0006606 51 0.041
Mouse
nucleobase containing compound catabolic process GO:0034655 165 0.041
regulation of secretion GO:0051046 44 0.041
Mouse
cell adhesion GO:0007155 136 0.041
positive regulation of catabolic process GO:0009896 105 0.041
peptidyl lysine modification GO:0018205 57 0.041
response to ketone GO:1901654 34 0.040
defense response to virus GO:0051607 23 0.040
circadian behavior GO:0048512 76 0.040
protein localization to nucleus GO:0034504 55 0.040
Mouse
positive regulation of transcription dna templated GO:0045893 266 0.040
Mouse
protein targeting to nucleus GO:0044744 51 0.040
Mouse
single organism nuclear import GO:1902593 51 0.040
Mouse
carboxylic acid metabolic process GO:0019752 92 0.040
cell proliferation GO:0008283 299 0.039
Mouse
macromolecule catabolic process GO:0009057 161 0.039
mitotic cell cycle phase transition GO:0044772 138 0.039
chromatin organization GO:0006325 207 0.039
protein complex assembly GO:0006461 200 0.038
Mouse
morphogenesis of a polarized epithelium GO:0001738 93 0.038
regulation of hydrolase activity GO:0051336 97 0.038
Human Mouse
epidermal growth factor receptor signaling pathway GO:0007173 58 0.038
single organism carbohydrate metabolic process GO:0044723 72 0.038
Mouse
ribonucleoside catabolic process GO:0042454 112 0.037
protein transport GO:0015031 155 0.037
Mouse
positive regulation of immune response GO:0050778 63 0.037
Mouse
purine nucleoside triphosphate catabolic process GO:0009146 108 0.037
regulation of immune effector process GO:0002697 52 0.037
Mouse
antimicrobial humoral response GO:0019730 99 0.036
regulation of antimicrobial peptide biosynthetic process GO:0002805 38 0.036
regulation of cellular component movement GO:0051270 42 0.036
Mouse
intracellular protein transport GO:0006886 104 0.035
Mouse
purine ribonucleoside catabolic process GO:0046130 112 0.035
regulation of purine nucleotide metabolic process GO:1900542 62 0.034
organic anion transport GO:0015711 28 0.034
Mouse
organonitrogen compound catabolic process GO:1901565 128 0.033
positive regulation of cellular amide metabolic process GO:0034250 26 0.033
positive regulation of cell development GO:0010720 61 0.033
Mouse
positive regulation of nucleic acid templated transcription GO:1903508 266 0.033
Mouse
positive regulation of mapk cascade GO:0043410 63 0.033
Mouse
regulation of cellular ketone metabolic process GO:0010565 3 0.033
single organism intracellular transport GO:1902582 207 0.032
Mouse
signal release GO:0023061 49 0.032
Mouse
cellular carbohydrate metabolic process GO:0044262 22 0.032
nucleoside catabolic process GO:0009164 112 0.032
response to hormone GO:0009725 45 0.032
regulation of ras protein signal transduction GO:0046578 93 0.032
rhythmic behavior GO:0007622 76 0.032
cellular response to ionizing radiation GO:0071479 15 0.032
response to heat GO:0009408 63 0.032
negative regulation of cell differentiation GO:0045596 143 0.032
Mouse
regulation of cell cycle phase transition GO:1901987 130 0.031
purine nucleotide metabolic process GO:0006163 146 0.031
chromosome organization GO:0051276 360 0.031
positive regulation of developmental process GO:0051094 143 0.031
Mouse
amine metabolic process GO:0009308 12 0.031
positive regulation of secretion GO:0051047 22 0.031
Mouse
biological adhesion GO:0022610 138 0.031
embryonic pattern specification GO:0009880 174 0.031
regulation of protein metabolic process GO:0051246 256 0.030
Human Mouse
response to temperature stimulus GO:0009266 106 0.030
negative regulation of cellular protein metabolic process GO:0032269 85 0.030
chitin based cuticle sclerotization GO:0007593 19 0.030
epithelial structure maintenance GO:0010669 17 0.030
mitotic spindle organization GO:0007052 220 0.030
heart process GO:0003015 37 0.030
locomotory behavior GO:0007626 176 0.030
aging GO:0007568 143 0.030
negative regulation of peptide secretion GO:0002792 1 0.030
renal system development GO:0072001 72 0.030
negative regulation of nucleobase containing compound metabolic process GO:0045934 261 0.030
Human Mouse
positive regulation of rna biosynthetic process GO:1902680 266 0.029
Mouse
compound eye retinal cell programmed cell death GO:0046667 23 0.029
synaptic growth at neuromuscular junction GO:0051124 119 0.029
positive regulation of cysteine type endopeptidase activity GO:2001056 24 0.029
Human Mouse
regulation of reproductive process GO:2000241 54 0.029
gene silencing by rna GO:0031047 57 0.029
regulation of vesicle mediated transport GO:0060627 59 0.029
nucleoside metabolic process GO:0009116 127 0.028
regulation of multicellular organismal development GO:2000026 414 0.028
Human Mouse
transmembrane receptor protein serine threonine kinase signaling pathway GO:0007178 65 0.028
glycosyl compound metabolic process GO:1901657 127 0.028
establishment of protein localization to organelle GO:0072594 62 0.028
Mouse
response to ionizing radiation GO:0010212 32 0.028
negative regulation of mitotic cell cycle GO:0045930 109 0.028
ras protein signal transduction GO:0007265 88 0.028
regulation of defense response to virus GO:0050688 14 0.028
axis specification GO:0009798 167 0.027
imaginal disc derived wing vein specification GO:0007474 48 0.027
regulation of transmembrane transporter activity GO:0022898 6 0.027
cell maturation GO:0048469 144 0.027
organic acid transport GO:0015849 18 0.027
Mouse
dna integrity checkpoint GO:0031570 81 0.027
regulation of cell proliferation GO:0042127 163 0.027
Mouse
activation of cysteine type endopeptidase activity GO:0097202 17 0.027
Human Mouse
imaginal disc derived wing margin morphogenesis GO:0008587 41 0.027
establishment or maintenance of cell polarity GO:0007163 167 0.027
regionalization GO:0003002 416 0.027
regulation of phosphate metabolic process GO:0019220 210 0.026
Mouse
regulation of retinal cell programmed cell death GO:0046668 18 0.026
posttranscriptional gene silencing by rna GO:0035194 45 0.026
organonitrogen compound biosynthetic process GO:1901566 117 0.026
response to alkaloid GO:0043279 26 0.026
organ or tissue specific immune response GO:0002251 10 0.026
positive regulation of apoptotic signaling pathway GO:2001235 4 0.026
Human Zebrafish
response to mechanical stimulus GO:0009612 28 0.026
regulation of anatomical structure morphogenesis GO:0022603 242 0.026
Human Mouse
regulation of peptidase activity GO:0052547 39 0.026
Human Mouse
camp metabolic process GO:0046058 19 0.026
epithelial cell morphogenesis involved in gastrulation GO:0003381 7 0.026
monocarboxylic acid transport GO:0015718 3 0.026
Mouse
positive regulation of jnk cascade GO:0046330 16 0.025
Mouse
imaginal disc derived leg morphogenesis GO:0007480 80 0.025
regulation of actin filament based process GO:0032970 42 0.025
monovalent inorganic cation transport GO:0015672 40 0.025
gastrulation GO:0007369 70 0.025
purine ribonucleotide catabolic process GO:0009154 109 0.025
branching involved in open tracheal system development GO:0060446 45 0.025
regulation of transmembrane receptor protein serine threonine kinase signaling pathway GO:0090092 38 0.025
homeostatic process GO:0042592 199 0.025
cytoskeleton dependent cytokinesis GO:0061640 81 0.025
gastrulation involving germ band extension GO:0010004 36 0.025
protein heterooligomerization GO:0051291 4 0.025
musculoskeletal movement GO:0050881 3 0.025
negative regulation of programmed cell death GO:0043069 72 0.025
retinal cell programmed cell death GO:0046666 25 0.024
Mouse
negative regulation of synaptic growth at neuromuscular junction GO:0045886 39 0.024
regulation of antibacterial peptide biosynthetic process GO:0002808 22 0.024
gene silencing GO:0016458 138 0.024
leg disc morphogenesis GO:0007478 80 0.024
protein complex localization GO:0031503 4 0.024
Mouse
secretion by cell GO:0032940 101 0.024
Mouse
mitotic dna integrity checkpoint GO:0044774 75 0.024
urogenital system development GO:0001655 72 0.024
regulation of smoothened signaling pathway GO:0008589 28 0.023
ribonucleotide catabolic process GO:0009261 109 0.023
purine nucleoside triphosphate metabolic process GO:0009144 119 0.023
antibacterial peptide production GO:0002778 22 0.023
regulation of cyclic nucleotide metabolic process GO:0030799 13 0.023
negative regulation of wnt signaling pathway GO:0030178 28 0.023
central nervous system development GO:0007417 201 0.023
regulation of catalytic activity GO:0050790 185 0.023
Human Mouse
mitotic nuclear division GO:0007067 213 0.023
regulation of cell migration GO:0030334 22 0.023
Mouse
regulation of response to dna damage stimulus GO:2001020 23 0.022
regulation of cell cycle GO:0051726 291 0.022
response to ethanol GO:0045471 59 0.022
macroautophagy GO:0016236 42 0.022
positive regulation of response to external stimulus GO:0032103 44 0.022
Mouse
cellular homeostasis GO:0019725 80 0.022
ion transport GO:0006811 145 0.022
Mouse
positive regulation of antibacterial peptide biosynthetic process GO:0006963 20 0.022
regulation of small gtpase mediated signal transduction GO:0051056 93 0.021
regulation of mitotic sister chromatid segregation GO:0033047 28 0.021
response to oxygen containing compound GO:1901700 200 0.021
Zebrafish Mouse
regulation of synapse assembly GO:0051963 94 0.021
execution phase of apoptosis GO:0097194 7 0.021
regulation of chromosome segregation GO:0051983 32 0.021
apoptotic cell clearance GO:0043277 14 0.021
purine ribonucleoside triphosphate catabolic process GO:0009207 108 0.020
negative regulation of phosphatidylinositol 3 kinase signaling GO:0014067 4 0.020
regulation of nervous system development GO:0051960 248 0.020
regulation of protein modification process GO:0031399 112 0.020
Mouse
regulation of locomotion GO:0040012 42 0.020
Mouse
glycerolipid metabolic process GO:0046486 34 0.020
regulation of canonical wnt signaling pathway GO:0060828 15 0.020
negative regulation of sequence specific dna binding transcription factor activity GO:0043433 4 0.020
cellular response to carbohydrate stimulus GO:0071322 4 0.020
sister chromatid segregation GO:0000819 92 0.020
negative regulation of cell cycle process GO:0010948 109 0.020
cytokinesis GO:0000910 90 0.020
regulation of transporter activity GO:0032409 6 0.020
respiratory system development GO:0060541 213 0.020
cellular response to organic cyclic compound GO:0071407 32 0.020
secretion GO:0046903 109 0.020
Mouse

egr disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in fly and predicted with the fly functional network.

Disease DO term ID Size Probability Func Analog Org
diabetes mellitus DOID:9351 0 0.057
disease of metabolism DOID:0014667 0 0.057
carbohydrate metabolism disease DOID:0050013 0 0.057
glucose metabolism disease DOID:4194 0 0.057
acquired metabolic disease DOID:0060158 0 0.057
cancer DOID:162 0 0.038
Human
disease of cellular proliferation DOID:14566 0 0.038
Human
type 2 diabetes mellitus DOID:9352 0 0.033
organ system cancer DOID:0050686 0 0.032
Human