Drosophila melanogaster

183 known processes

lkb1 (Dmel_CG9374)

CG9374 gene product from transcript CG9374-RJ

(Aliases: dlkb1,par-4,DmLKB1,CG9374,STK11,LKB1/PEUTZ JEGHERS KINASE,Lkb1,PAR4,Dmel\CG9374,LKB1,anon-EST:Posey135,PAR-4,dLKB1)

lkb1 biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
localization of cell GO:0051674 257 0.974
ovarian follicle cell development GO:0030707 248 0.962
ovarian follicle cell migration GO:0007297 121 0.954
epithelial cell development GO:0002064 274 0.922
border follicle cell migration GO:0007298 113 0.907
epithelial cell differentiation GO:0030855 322 0.899
cell migration GO:0016477 238 0.898
cell motility GO:0048870 251 0.895
epithelium migration GO:0090132 148 0.886
centrosome cycle GO:0007098 137 0.873
centrosome duplication GO:0051298 121 0.823
tissue migration GO:0090130 155 0.771
ameboidal type cell migration GO:0001667 151 0.757
centrosome organization GO:0051297 163 0.738
cell proliferation GO:0008283 299 0.734
developmental growth GO:0048589 280 0.673
Mouse
epithelial cell migration GO:0010631 148 0.667
spindle organization GO:0007051 253 0.631
organelle localization GO:0051640 148 0.578
Mouse
columnar cuboidal epithelial cell differentiation GO:0002065 256 0.508
columnar cuboidal epithelial cell development GO:0002066 249 0.477
microtubule organizing center organization GO:0031023 168 0.419
regulation of protein metabolic process GO:0051246 256 0.332
Human Mouse
transmembrane receptor protein tyrosine kinase signaling pathway GO:0007169 116 0.324
centrosome separation GO:0051299 20 0.322
establishment or maintenance of cell polarity GO:0007163 167 0.314
nuclear division GO:0000280 332 0.303
asymmetric neuroblast division GO:0055059 33 0.296
regulation of phosphorylation GO:0042325 147 0.288
cilium organization GO:0044782 41 0.287
stem cell proliferation GO:0072089 88 0.272
growth GO:0040007 359 0.271
Mouse
organelle assembly GO:0070925 198 0.267
larval development GO:0002164 104 0.264
Worm
centriole centriole cohesion GO:0010457 5 0.261
homeostatic process GO:0042592 199 0.256
Zebrafish Mouse
stem cell division GO:0017145 69 0.237
immune system process GO:0002376 347 0.233
Mouse
oocyte microtubule cytoskeleton organization GO:0016325 35 0.223
establishment of cell polarity GO:0030010 40 0.221
Mouse Worm
cell division GO:0051301 248 0.212
establishment of localization in cell GO:0051649 402 0.212
microtubule based transport GO:0010970 42 0.211
regulation of growth GO:0040008 233 0.206
Mouse
ribonucleoside triphosphate metabolic process GO:0009199 119 0.206
somatic stem cell division GO:0048103 37 0.205
mitotic centrosome separation GO:0007100 8 0.204
establishment of organelle localization GO:0051656 122 0.203
negative regulation of cytoskeleton organization GO:0051494 30 0.191
pronuclear migration GO:0035046 4 0.189
cytoskeleton dependent cytokinesis GO:0061640 81 0.187
Worm
appendage development GO:0048736 401 0.185
microtubule based movement GO:0007018 51 0.185
tissue morphogenesis GO:0048729 297 0.185
mitotic nuclear division GO:0007067 213 0.184
protein polymerization GO:0051258 42 0.174
actin filament based process GO:0030029 220 0.169
centriole replication GO:0007099 24 0.169
nucleus localization GO:0051647 34 0.167
establishment or maintenance of cytoskeleton polarity GO:0030952 44 0.166
oocyte axis specification GO:0007309 108 0.164
eye photoreceptor cell differentiation GO:0001754 145 0.163
actin cytoskeleton organization GO:0030036 206 0.161
mitotic spindle organization GO:0007052 220 0.160
establishment or maintenance of apical basal cell polarity GO:0035088 34 0.157
immune response GO:0006955 246 0.154
Mouse
cell maturation GO:0048469 144 0.153
organ growth GO:0035265 56 0.148
protein modification process GO:0036211 438 0.147
Human Mouse Worm
establishment of nucleus localization GO:0040023 26 0.139
appendage morphogenesis GO:0035107 397 0.134
cytokinesis GO:0000910 90 0.132
Worm
axon development GO:0061564 297 0.131
Mouse
nuclear migration GO:0007097 20 0.129
endomembrane system organization GO:0010256 119 0.128
protein localization GO:0008104 284 0.128
Worm
oocyte differentiation GO:0009994 145 0.126
establishment of spindle orientation GO:0051294 18 0.122
oocyte development GO:0048599 124 0.122
enzyme linked receptor protein signaling pathway GO:0007167 179 0.119
Human Mouse
central nervous system development GO:0007417 201 0.119
protein phosphorylation GO:0006468 169 0.117
Human Mouse Worm
mitotic cell cycle embryonic GO:0045448 38 0.115
intracellular mrna localization involved in anterior posterior axis specification GO:0060811 53 0.114
reproductive structure development GO:0048608 74 0.113
Mouse
small molecule metabolic process GO:0044281 305 0.112
single organism cellular localization GO:1902580 180 0.111
regulation of microtubule cytoskeleton organization GO:0070507 41 0.109
microtubule polymerization or depolymerization GO:0031109 39 0.108
macromolecular complex assembly GO:0065003 256 0.108
Mouse
catabolic process GO:0009056 409 0.105
oocyte construction GO:0007308 112 0.105
establishment or maintenance of microtubule cytoskeleton polarity GO:0030951 41 0.101
organelle fission GO:0048285 340 0.100
regulation of cell proliferation GO:0042127 163 0.100
Human Mouse
regulation of developmental growth GO:0048638 174 0.100
developmental maturation GO:0021700 172 0.097
neuronal stem cell division GO:0036445 35 0.097
wing disc morphogenesis GO:0007472 344 0.096
spindle assembly involved in mitosis GO:0090307 50 0.095
organonitrogen compound metabolic process GO:1901564 318 0.094
anatomical structure homeostasis GO:0060249 97 0.093
Mouse
maintenance of location GO:0051235 73 0.093
asymmetric cell division GO:0008356 37 0.093
Worm
positive regulation of response to stimulus GO:0048584 323 0.088
Human Mouse
microtubule polymerization GO:0046785 15 0.087
pole plasm oskar mrna localization GO:0045451 46 0.087
cilium morphogenesis GO:0060271 39 0.086
establishment or maintenance of bipolar cell polarity GO:0061245 34 0.084
intracellular mrna localization involved in pattern specification process GO:0060810 56 0.083
pole plasm rna localization GO:0007316 52 0.083
neuromuscular junction development GO:0007528 149 0.083
pole plasm mrna localization GO:0019094 49 0.082
establishment of mitotic spindle orientation GO:0000132 13 0.082
single organism intracellular transport GO:1902582 207 0.082
negative regulation of response to stimulus GO:0048585 258 0.080
nucleoside phosphate metabolic process GO:0006753 162 0.080
negative regulation of phosphorus metabolic process GO:0010563 45 0.080
apoptotic process GO:0006915 159 0.077
centriole assembly GO:0098534 24 0.076
spermatogenesis GO:0007283 200 0.075
Mouse
axonogenesis GO:0007409 290 0.074
Mouse
morphogenesis of an epithelium GO:0002009 276 0.074
nucleotide catabolic process GO:0009166 109 0.074
tube development GO:0035295 244 0.073
Zebrafish
response to oxidative stress GO:0006979 86 0.073
Worm
hematopoietic or lymphoid organ development GO:0048534 57 0.073
Mouse
sensory perception GO:0007600 196 0.072
positive regulation of signaling GO:0023056 243 0.072
Human Mouse
eye development GO:0001654 323 0.071
embryonic morphogenesis GO:0048598 206 0.070
regulation of molecular function GO:0065009 217 0.069
Human Mouse
cytoskeleton dependent intracellular transport GO:0030705 44 0.069
tube morphogenesis GO:0035239 191 0.069
regulation of phosphate metabolic process GO:0019220 210 0.069
regulation of cellular localization GO:0060341 136 0.068
positive regulation of developmental process GO:0051094 143 0.066
Mouse Worm
non sensory hair organization GO:0035316 47 0.066
development of primary sexual characteristics GO:0045137 50 0.065
regulation of catalytic activity GO:0050790 185 0.064
Human Mouse
regulation of organelle organization GO:0033043 196 0.064
regulation of mitotic cell cycle GO:0007346 190 0.063
ribose phosphate metabolic process GO:0019693 145 0.063
positive regulation of multicellular organismal process GO:0051240 143 0.062
Mouse Worm
positive regulation of protein transport GO:0051222 37 0.062
spermatid differentiation GO:0048515 114 0.062
Mouse
regulation of microtubule based process GO:0032886 49 0.061
germarium derived oocyte differentiation GO:0030706 29 0.061
ribonucleoside triphosphate catabolic process GO:0009203 108 0.060
organic substance transport GO:0071702 257 0.060
meiotic nuclear division GO:0007126 151 0.059
regulation of protein transport GO:0051223 57 0.059
cell projection assembly GO:0030031 94 0.057
compound eye photoreceptor cell differentiation GO:0001751 140 0.057
mitotic spindle stabilization GO:0043148 6 0.055
protein complex biogenesis GO:0070271 201 0.055
Mouse
macromolecular complex disassembly GO:0032984 37 0.055
oxoacid metabolic process GO:0043436 103 0.053
cytoplasmic transport nurse cell to oocyte GO:0007303 12 0.053
phosphorylation GO:0016310 294 0.052
digestive tract development GO:0048565 149 0.052
Zebrafish
establishment of spindle localization GO:0051293 22 0.052
sensory organ morphogenesis GO:0090596 260 0.052
embryonic development via the syncytial blastoderm GO:0001700 148 0.052
imaginal disc growth GO:0007446 37 0.052
carbohydrate derivative metabolic process GO:1901135 217 0.051
ribonucleotide metabolic process GO:0009259 145 0.050
imaginal disc derived appendage morphogenesis GO:0035114 395 0.050
protein transport GO:0015031 155 0.049
regulation of embryonic development GO:0045995 68 0.048
negative regulation of programmed cell death GO:0043069 72 0.048
ribonucleotide catabolic process GO:0009261 109 0.048
anterograde axon cargo transport GO:0008089 6 0.047
purine ribonucleotide metabolic process GO:0009150 145 0.046
regulation of anatomical structure morphogenesis GO:0022603 242 0.046
Mouse
asymmetric stem cell division GO:0098722 49 0.046
dendrite development GO:0016358 204 0.046
Mouse
purine nucleotide metabolic process GO:0006163 146 0.045
organic substance catabolic process GO:1901575 308 0.045
golgi organization GO:0007030 66 0.045
microtubule bundle formation GO:0001578 27 0.045
nucleobase containing small molecule metabolic process GO:0055086 174 0.045
cellular protein modification process GO:0006464 438 0.045
Human Mouse Worm
regulation of phosphorus metabolic process GO:0051174 210 0.045
glycosyl compound metabolic process GO:1901657 127 0.044
nuclear import GO:0051170 51 0.044
purine ribonucleotide catabolic process GO:0009154 109 0.044
compound eye development GO:0048749 307 0.044
imaginal disc derived appendage development GO:0048737 399 0.044
negative regulation of protein metabolic process GO:0051248 85 0.044
neurological system process GO:0050877 358 0.043
purine ribonucleoside metabolic process GO:0046128 127 0.043
morphogenesis of follicular epithelium GO:0016333 36 0.042
epidermal cell differentiation GO:0009913 51 0.042
ribonucleoside metabolic process GO:0009119 127 0.042
regulation of localization GO:0032879 275 0.042
negative regulation of phosphate metabolic process GO:0045936 45 0.041
organophosphate metabolic process GO:0019637 195 0.041
axon cargo transport GO:0008088 29 0.041
photoreceptor cell differentiation GO:0046530 170 0.041
cellular nitrogen compound catabolic process GO:0044270 165 0.041
cellular component assembly involved in morphogenesis GO:0010927 151 0.041
mitotic cytokinesis GO:0000281 50 0.040
organelle fusion GO:0048284 46 0.040
cell growth GO:0016049 108 0.040
Mouse
digestive system development GO:0055123 149 0.040
Zebrafish
glycosyl compound catabolic process GO:1901658 112 0.040
regulation of cyclin dependent protein serine threonine kinase activity GO:0000079 3 0.040
organonitrogen compound catabolic process GO:1901565 128 0.039
forebrain development GO:0030900 2 0.039
cellular macromolecule localization GO:0070727 220 0.039
erbb signaling pathway GO:0038127 58 0.039
vesicle mediated transport GO:0016192 381 0.039
positive regulation of signal transduction GO:0009967 223 0.039
Human Mouse
negative regulation of protein depolymerization GO:1901880 23 0.039
gland development GO:0048732 191 0.038
Mouse
negative regulation of developmental process GO:0051093 201 0.038
Mouse
cellular response to chemical stimulus GO:0070887 199 0.038
Human Mouse
membrane disassembly GO:0030397 4 0.038
protein import into nucleus GO:0006606 51 0.038
eye photoreceptor cell development GO:0042462 81 0.038
photoreceptor cell development GO:0042461 96 0.038
body morphogenesis GO:0010171 2 0.037
intracellular transport GO:0046907 228 0.037
sensory perception of mechanical stimulus GO:0050954 72 0.037
nucleoside triphosphate metabolic process GO:0009141 120 0.037
response to insulin GO:0032868 29 0.036
carboxylic acid metabolic process GO:0019752 92 0.036
chorion containing eggshell formation GO:0007304 105 0.036
reproductive system development GO:0061458 74 0.036
Mouse
spindle assembly GO:0051225 80 0.036
establishment of mitotic spindle localization GO:0040001 17 0.035
regulation of cell size GO:0008361 63 0.035
single organism membrane organization GO:0044802 93 0.035
mapk cascade GO:0000165 107 0.034
metaphase plate congression GO:0051310 19 0.034
nucleoside metabolic process GO:0009116 127 0.034
hindbrain development GO:0030902 2 0.034
head development GO:0060322 135 0.034
membrane organization GO:0061024 112 0.034
regulation of spindle organization GO:0090224 17 0.033
cell junction organization GO:0034330 57 0.033
nucleotide metabolic process GO:0009117 161 0.033
regulation of neuron differentiation GO:0045664 103 0.032
Mouse
maintenance of protein location GO:0045185 28 0.032
negative regulation of nervous system development GO:0051961 92 0.032
regulation of immune system process GO:0002682 176 0.032
Mouse
programmed cell death GO:0012501 257 0.032
cystoblast division GO:0007282 10 0.032
mitotic sister chromatid segregation GO:0000070 87 0.032
hair cell differentiation GO:0035315 47 0.032
purine containing compound catabolic process GO:0072523 112 0.032
atp metabolic process GO:0046034 49 0.031
cellular homeostasis GO:0019725 80 0.031
purine ribonucleoside triphosphate metabolic process GO:0009205 119 0.031
neuroblast division GO:0055057 35 0.031
tripartite regional subdivision GO:0007351 103 0.031
maintenance of location in cell GO:0051651 28 0.031
digestive tract morphogenesis GO:0048546 127 0.030
regulation of mitosis GO:0007088 56 0.030
cellular amine metabolic process GO:0044106 12 0.030
regulation of transport GO:0051049 181 0.030
regulation of cellular ketone metabolic process GO:0010565 3 0.030
synaptic vesicle endocytosis GO:0048488 28 0.030
regulation of protein depolymerization GO:1901879 27 0.029
spindle stabilization GO:0043146 14 0.029
compound eye morphogenesis GO:0001745 249 0.029
syncytial blastoderm mitotic cell cycle GO:0035186 21 0.029
regulation of mitotic spindle organization GO:0060236 9 0.029
positive regulation of proteasomal protein catabolic process GO:1901800 20 0.029
neural precursor cell proliferation GO:0061351 75 0.029
establishment of apical basal cell polarity GO:0035089 12 0.029
cellular macromolecular complex assembly GO:0034622 153 0.029
negative regulation of apoptotic process GO:0043066 63 0.029
regulation of microtubule depolymerization GO:0031114 24 0.028
morphogenesis of a polarized epithelium GO:0001738 93 0.028
negative regulation of molecular function GO:0044092 51 0.028
purine nucleoside catabolic process GO:0006152 112 0.028
oocyte anterior posterior axis specification GO:0007314 72 0.028
regulation of microtubule polymerization or depolymerization GO:0031110 27 0.028
regulation of cellular component movement GO:0051270 42 0.028
male meiosis cytokinesis GO:0007112 26 0.028
meiosis i GO:0007127 59 0.027
negative regulation of protein complex disassembly GO:0043242 23 0.027
germarium derived egg chamber formation GO:0007293 101 0.027
immune effector process GO:0002252 98 0.027
cellular protein complex disassembly GO:0043624 35 0.027
cellular ketone metabolic process GO:0042180 24 0.027
sex differentiation GO:0007548 81 0.027
protein depolymerization GO:0051261 31 0.027
regulation of cell death GO:0010941 173 0.027
regulation of protein modification process GO:0031399 112 0.027
Human Mouse
spindle assembly involved in female meiosis GO:0007056 14 0.027
negative regulation of phosphorylation GO:0042326 35 0.027
positive regulation of wnt signaling pathway GO:0030177 25 0.027
purine nucleoside metabolic process GO:0042278 127 0.026
post embryonic appendage morphogenesis GO:0035120 385 0.026
regulation of cell development GO:0060284 215 0.026
Mouse
death GO:0016265 284 0.026
regulation of nuclear division GO:0051783 58 0.026
positive regulation of cell communication GO:0010647 250 0.026
Human Mouse
macromolecule catabolic process GO:0009057 161 0.026
protein localization to organelle GO:0033365 82 0.026
epidermis development GO:0008544 65 0.026
brain development GO:0007420 120 0.026
purine ribonucleoside triphosphate catabolic process GO:0009207 108 0.026
cellular ion homeostasis GO:0006873 39 0.026
regulation of apoptotic process GO:0042981 130 0.026
cell death GO:0008219 279 0.025
cellular cation homeostasis GO:0030003 38 0.025
regulation of cysteine type endopeptidase activity involved in apoptotic process GO:0043281 25 0.025
translation GO:0006412 69 0.025
negative regulation of microtubule polymerization or depolymerization GO:0031111 21 0.025
axoneme assembly GO:0035082 18 0.025
spindle localization GO:0051653 22 0.025
response to wounding GO:0009611 94 0.025
regulation of multicellular organismal development GO:2000026 414 0.025
Mouse Worm
adherens junction organization GO:0034332 27 0.025
zonula adherens assembly GO:0045186 6 0.025
maintenance of cell polarity GO:0030011 18 0.025
regulation of protein localization GO:0032880 76 0.025
positive regulation of transport GO:0051050 92 0.025
stem cell differentiation GO:0048863 117 0.024
regulation of cell division GO:0051302 72 0.024
Worm
imaginal disc derived wing hair organization GO:0035317 45 0.024
mitochondrion organization GO:0007005 65 0.024
regulation of cytoskeleton organization GO:0051493 89 0.024
imaginal disc derived wing morphogenesis GO:0007476 337 0.024
regulation of programmed cell death GO:0043067 152 0.024
purine nucleotide catabolic process GO:0006195 109 0.024
negative regulation of neuron death GO:1901215 18 0.024
axis specification GO:0009798 167 0.024
aromatic compound catabolic process GO:0019439 166 0.023
cellular metal ion homeostasis GO:0006875 31 0.023
cellular protein complex assembly GO:0043623 71 0.023
carbohydrate derivative catabolic process GO:1901136 118 0.023
protein complex assembly GO:0006461 200 0.023
Mouse
vesicle organization GO:0016050 44 0.023
positive regulation of mitotic sister chromatid separation GO:1901970 10 0.023
regulation of rab protein signal transduction GO:0032483 7 0.023
microtubule depolymerization GO:0007019 25 0.023
muscle organ development GO:0007517 127 0.023
protein targeting to nucleus GO:0044744 51 0.023
centrosome localization GO:0051642 14 0.023
axon guidance GO:0007411 233 0.023
intracellular signal transduction GO:0035556 300 0.023
embryonic hemopoiesis GO:0035162 26 0.022
microtubule anchoring GO:0034453 11 0.022
negative regulation of transmembrane receptor protein serine threonine kinase signaling pathway GO:0090101 18 0.022
regulation of neuron death GO:1901214 26 0.022
germarium derived oocyte fate determination GO:0007294 26 0.022
regulation of cell cycle GO:0051726 291 0.022
Human Worm
organic acid metabolic process GO:0006082 103 0.022
nucleoside monophosphate metabolic process GO:0009123 52 0.022
nucleoside phosphate catabolic process GO:1901292 110 0.022
cytokinetic cell separation GO:0000920 1 0.021
establishment of tissue polarity GO:0007164 87 0.021
chromosome organization GO:0051276 360 0.021
negative regulation of microtubule depolymerization GO:0007026 21 0.021
extrinsic apoptotic signaling pathway GO:0097191 1 0.021
positive regulation of growth GO:0045927 75 0.021
skin development GO:0043588 65 0.021
posttranscriptional gene silencing by rna GO:0035194 45 0.021
regulation of multicellular organism growth GO:0040014 40 0.021
purine ribonucleoside catabolic process GO:0046130 112 0.021
regulation of establishment of protein localization GO:0070201 61 0.021
microtubule cytoskeleton organization involved in mitosis GO:1902850 52 0.021
epidermal growth factor receptor signaling pathway GO:0007173 58 0.021
multicellular organismal aging GO:0010259 140 0.021
positive regulation of catabolic process GO:0009896 105 0.021
nf kappab import into nucleus GO:0042348 1 0.021
purine containing compound metabolic process GO:0072521 155 0.021
embryo development ending in birth or egg hatching GO:0009792 152 0.021
immune system development GO:0002520 57 0.021
Mouse
nucleoside catabolic process GO:0009164 112 0.021
small gtpase mediated signal transduction GO:0007264 88 0.021
cation homeostasis GO:0055080 51 0.020
regulation of protein import into nucleus GO:0042306 28 0.020
gastrulation involving germ band extension GO:0010004 36 0.020
male gamete generation GO:0048232 201 0.020
Mouse
gonad development GO:0008406 50 0.020
establishment of vesicle localization GO:0051650 51 0.020
positive regulation of histone deacetylation GO:0031065 2 0.020
cell cycle comprising mitosis without cytokinesis GO:0033301 25 0.020
positive regulation of phosphorus metabolic process GO:0010562 139 0.020
Human Mouse
negative regulation of developmental growth GO:0048640 64 0.020
cell aging GO:0007569 2 0.020
positive regulation of phosphorylation GO:0042327 87 0.020
Human Mouse
regulation of cellular amino acid metabolic process GO:0006521 0 0.020
photoreceptor cell maintenance GO:0045494 11 0.020
response to toxic substance GO:0009636 22 0.020
single organism catabolic process GO:0044712 228 0.020
regulation of synaptic growth at neuromuscular junction GO:0008582 89 0.019
establishment of epithelial cell polarity GO:0090162 13 0.019
delamination GO:0060232 8 0.019
cellular response to oxidative stress GO:0034599 28 0.019
lymph gland development GO:0048542 28 0.019
heterocycle catabolic process GO:0046700 166 0.019
eye morphogenesis GO:0048592 260 0.019
pronuclear fusion GO:0007344 4 0.019
single fertilization GO:0007338 24 0.019
cytoplasmic transport GO:0016482 130 0.019
negative regulation of protein polymerization GO:0032272 7 0.019
regulation of immune response GO:0050776 118 0.019
Mouse
positive regulation of nucleocytoplasmic transport GO:0046824 24 0.018
nuclear transport GO:0051169 72 0.018
secretion by cell GO:0032940 101 0.018
regulation of transferase activity GO:0051338 58 0.018
Human Mouse
regulation of centrosome cycle GO:0046605 7 0.018
eye antennal disc morphogenesis GO:0007455 34 0.018
secretion GO:0046903 109 0.018
negative regulation of cellular component organization GO:0051129 108 0.018
regulation of cell growth GO:0001558 43 0.018
Mouse
signal transduction by phosphorylation GO:0023014 107 0.018
epithelial tube morphogenesis GO:0060562 88 0.018
apical protein localization GO:0045176 5 0.018
positive regulation of protein localization to nucleus GO:1900182 21 0.018
transcription from rna polymerase ii promoter GO:0006366 368 0.018
positive regulation of macromolecule metabolic process GO:0010604 405 0.018
Human Mouse
muscle structure development GO:0061061 224 0.018
regulation of intracellular signal transduction GO:1902531 236 0.017
response to other organism GO:0051707 293 0.017
biological adhesion GO:0022610 138 0.017
negative regulation of cell death GO:0060548 81 0.017
positive regulation of cell proliferation GO:0008284 47 0.017
positive regulation of proteolysis GO:0045862 52 0.017
regulation of cellular component biogenesis GO:0044087 201 0.017
regulation of epidermal growth factor receptor signaling pathway GO:0042058 42 0.017
response to organic substance GO:0010033 284 0.017
Human Mouse
proteolysis GO:0006508 192 0.017
cell cell junction organization GO:0045216 55 0.017
pole plasm assembly GO:0007315 61 0.017
cilium assembly GO:0042384 38 0.017
regulation of notch signaling pathway GO:0008593 100 0.017
establishment of epithelial cell apical basal polarity GO:0045198 10 0.017
protein localization to nucleus GO:0034504 55 0.017
cell type specific apoptotic process GO:0097285 38 0.017
nucleobase containing compound catabolic process GO:0034655 165 0.017
generation of precursor metabolites and energy GO:0006091 42 0.017
purine nucleoside triphosphate catabolic process GO:0009146 108 0.017
negative regulation of growth GO:0045926 84 0.017
Mouse
organophosphate catabolic process GO:0046434 112 0.016
phospholipid homeostasis GO:0055091 1 0.016
positive regulation of rna metabolic process GO:0051254 271 0.016
apoptotic signaling pathway GO:0097190 27 0.016
Human
regulation of locomotion GO:0040012 42 0.016
Worm
establishment or maintenance of neuroblast polarity GO:0045196 8 0.016
regulation of bmp signaling pathway GO:0030510 23 0.016
ribonucleoside catabolic process GO:0042454 112 0.016
single organism nuclear import GO:1902593 51 0.016
negative regulation of neuron apoptotic process GO:0043524 14 0.016
response to hypoxia GO:0001666 53 0.016
fusome organization GO:0045478 13 0.016
regulation of neurogenesis GO:0050767 158 0.016
Mouse
polarized epithelial cell differentiation GO:0030859 10 0.016
regulation of transcription factor import into nucleus GO:0042990 22 0.016
peptidyl threonine phosphorylation GO:0018107 2 0.016
Worm
negative regulation of multicellular organismal process GO:0051241 142 0.015
Mouse
spindle assembly involved in male meiosis GO:0007053 5 0.015
organic hydroxy compound metabolic process GO:1901615 83 0.015
cuticle development GO:0042335 86 0.015
regulation of nervous system development GO:0051960 248 0.015
Mouse
oocyte nucleus localization involved in oocyte dorsal ventral axis specification GO:0051663 12 0.015
open tracheal system development GO:0007424 204 0.015
negative regulation of protein modification process GO:0031400 29 0.015
cellular component disassembly GO:0022411 46 0.015
respiratory system development GO:0060541 213 0.015
response to external biotic stimulus GO:0043207 293 0.015
regulation of protein phosphorylation GO:0001932 64 0.015
Human Mouse
neuron projection guidance GO:0097485 241 0.015
cellular protein localization GO:0034613 160 0.015
response to biotic stimulus GO:0009607 294 0.015
intracellular protein transport GO:0006886 104 0.015
plasma membrane organization GO:0007009 26 0.015
regulation of dendrite development GO:0050773 37 0.015
Mouse
regulation of protein modification by small protein conjugation or removal GO:1903320 25 0.015
cellularization GO:0007349 90 0.015
signal release GO:0023061 49 0.015
negative regulation of cellular protein metabolic process GO:0032269 85 0.015
cellular response to radiation GO:0071478 52 0.015
multicellular organismal homeostasis GO:0048871 41 0.014
Zebrafish Mouse
embryonic organ development GO:0048568 50 0.014
negative regulation of catalytic activity GO:0043086 42 0.014
positive regulation of nucleic acid templated transcription GO:1903508 266 0.014
chemical homeostasis GO:0048878 92 0.014
Mouse
neuron apoptotic process GO:0051402 17 0.014
endocytosis GO:0006897 310 0.014
regulation of mapk cascade GO:0043408 92 0.014
cellular chemical homeostasis GO:0055082 40 0.014
positive regulation of intracellular transport GO:0032388 42 0.014
ovarian fusome organization GO:0030723 11 0.014
response to abiotic stimulus GO:0009628 341 0.014
Mouse
cellular catabolic process GO:0044248 372 0.014
regulation of cell cell adhesion GO:0022407 21 0.014
metal ion transport GO:0030001 74 0.014

lkb1 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in fly and predicted with the fly functional network.

Disease DO term ID Size Probability Func Analog Org
disease of anatomical entity DOID:7 0 0.027
Human