Drosophila melanogaster

2 known processes

alpha-Est5 (Dmel_CG1089)

alpha-Esterase-5

(Aliases: EST-C,aE5,D,ESTC,DmalphaE5,Est-c,CG1089,Est-C,alphaE5,Est-9,EST9,Dmel\CG1089)

alpha-Est5 biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
post embryonic appendage morphogenesis GO:0035120 385 0.153
imaginal disc derived appendage development GO:0048737 399 0.108
wing disc morphogenesis GO:0007472 344 0.108
imaginal disc derived appendage morphogenesis GO:0035114 395 0.105
appendage morphogenesis GO:0035107 397 0.102
imaginal disc derived wing morphogenesis GO:0007476 337 0.101
small molecule metabolic process GO:0044281 305 0.095
defense response GO:0006952 300 0.081
appendage development GO:0048736 401 0.076
neurotransmitter metabolic process GO:0042133 2 0.075
organonitrogen compound metabolic process GO:1901564 318 0.072
response to other organism GO:0051707 293 0.063
ethanolamine containing compound metabolic process GO:0042439 4 0.063
chemotaxis GO:0006935 249 0.060
catabolic process GO:0009056 409 0.058
establishment of localization in cell GO:0051649 402 0.057
cellular catabolic process GO:0044248 372 0.052
response to external biotic stimulus GO:0043207 293 0.052
response to organic substance GO:0010033 284 0.051
neuron projection guidance GO:0097485 241 0.050
axon guidance GO:0007411 233 0.050
choline metabolic process GO:0019695 1 0.048
axonogenesis GO:0007409 290 0.047
single organism biosynthetic process GO:0044711 206 0.046
taxis GO:0042330 304 0.046
response to monosaccharide GO:0034284 4 0.046
single organism catabolic process GO:0044712 228 0.046
response to abiotic stimulus GO:0009628 341 0.046
epithelial cell development GO:0002064 274 0.045
cellular amino acid metabolic process GO:0006520 61 0.044
organic substance catabolic process GO:1901575 308 0.044
motor neuron axon guidance GO:0008045 58 0.044
organic substance transport GO:0071702 257 0.043
neuron recognition GO:0008038 101 0.043
columnar cuboidal epithelial cell development GO:0002066 249 0.043
carboxylic acid metabolic process GO:0019752 92 0.042
acetate ester metabolic process GO:1900619 2 0.042
cellular amine metabolic process GO:0044106 12 0.041
ovarian follicle cell development GO:0030707 248 0.041
organic acid metabolic process GO:0006082 103 0.041
amine catabolic process GO:0009310 1 0.040
amine metabolic process GO:0009308 12 0.040
oxoacid metabolic process GO:0043436 103 0.039
acetylcholine catabolic process GO:0006581 1 0.038
synaptic transmission GO:0007268 288 0.038
synaptic target recognition GO:0008039 45 0.038
defense response to other organism GO:0098542 225 0.037
response to oxygen containing compound GO:1901700 200 0.036
lateral inhibition GO:0046331 206 0.036
ameboidal type cell migration GO:0001667 151 0.035
acetylcholine metabolic process GO:0008291 2 0.035
epithelial cell differentiation GO:0030855 322 0.034
phagocytosis GO:0006909 215 0.034
regulation of cellular ketone metabolic process GO:0010565 3 0.034
cell cell signaling involved in cell fate commitment GO:0045168 210 0.033
secondary metabolic process GO:0019748 75 0.033
immune system process GO:0002376 347 0.033
neurotransmitter catabolic process GO:0042135 1 0.033
single organism behavior GO:0044708 391 0.032
pigment metabolic process GO:0042440 84 0.032
respiratory system development GO:0060541 213 0.031
vesicle mediated transport GO:0016192 381 0.031
organelle fission GO:0048285 340 0.031
response to organophosphorus GO:0046683 2 0.031
melanotic encapsulation of foreign target GO:0035011 30 0.031
anion homeostasis GO:0055081 3 0.030
choline catabolic process GO:0042426 1 0.030
localization of cell GO:0051674 257 0.029
protein transmembrane transport GO:0071806 4 0.029
protein modification process GO:0036211 438 0.029
positive regulation of macromolecule metabolic process GO:0010604 405 0.029
organophosphate metabolic process GO:0019637 195 0.029
tissue migration GO:0090130 155 0.029
male mating behavior GO:0060179 70 0.028
chromosome segregation GO:0007059 157 0.028
cellular ketone metabolic process GO:0042180 24 0.028
nucleobase containing small molecule metabolic process GO:0055086 174 0.028
cellular protein modification process GO:0006464 438 0.028
response to light stimulus GO:0009416 124 0.028
non sensory hair organization GO:0035316 47 0.028
intracellular transport GO:0046907 228 0.027
determination of adult lifespan GO:0008340 137 0.027
epithelial cell migration GO:0010631 148 0.027
cell motility GO:0048870 251 0.026
cellular biogenic amine catabolic process GO:0042402 1 0.026
carbohydrate derivative metabolic process GO:1901135 217 0.026
columnar cuboidal epithelial cell differentiation GO:0002065 256 0.026
nuclear division GO:0000280 332 0.026
cell migration GO:0016477 238 0.026
border follicle cell migration GO:0007298 113 0.025
female meiosis chromosome segregation GO:0016321 33 0.025
organic hydroxy compound metabolic process GO:1901615 83 0.025
response to glucose GO:0009749 2 0.025
steroid catabolic process GO:0006706 1 0.025
positive regulation of cellular biosynthetic process GO:0031328 316 0.025
open tracheal system development GO:0007424 204 0.025
cell recognition GO:0008037 102 0.024
regulation of localization GO:0032879 275 0.024
axon development GO:0061564 297 0.024
response to radiation GO:0009314 155 0.024
endocytosis GO:0006897 310 0.024
secretion by cell GO:0032940 101 0.024
melanin metabolic process GO:0006582 47 0.023
multicellular organismal aging GO:0010259 140 0.023
carbohydrate metabolic process GO:0005975 82 0.023
xenobiotic catabolic process GO:0042178 1 0.023
response to lipopolysaccharide GO:0032496 4 0.023
cell death GO:0008219 279 0.023
pyridine containing compound metabolic process GO:0072524 3 0.023
epithelium migration GO:0090132 148 0.023
melanization defense response GO:0035006 45 0.022
spermatogenesis GO:0007283 200 0.022
imaginal disc derived wing hair organization GO:0035317 45 0.022
response to hexose GO:0009746 3 0.021
telencephalon development GO:0021537 2 0.021
phospholipid homeostasis GO:0055091 1 0.021
oxidoreduction coenzyme metabolic process GO:0006733 2 0.021
acylglycerol biosynthetic process GO:0046463 2 0.021
response to temperature stimulus GO:0009266 106 0.021
positive regulation of signaling GO:0023056 243 0.020
regionalization GO:0003002 416 0.020
regulation of cell cycle GO:0051726 291 0.020
nucleoside phosphate metabolic process GO:0006753 162 0.020
positive regulation of macromolecule biosynthetic process GO:0010557 283 0.020
negative regulation of cellular metabolic process GO:0031324 382 0.020
regulation of anatomical structure size GO:0090066 163 0.020
positive regulation of response to stimulus GO:0048584 323 0.020
positive regulation of biosynthetic process GO:0009891 316 0.020
spermatid differentiation GO:0048515 114 0.020
phenol containing compound metabolic process GO:0018958 57 0.020
response to bacterium GO:0009617 198 0.020
mating GO:0007618 120 0.020
heterocycle catabolic process GO:0046700 166 0.020
triglyceride biosynthetic process GO:0019432 2 0.020
transmembrane transport GO:0055085 139 0.019
phototaxis GO:0042331 21 0.019
positive regulation of transport GO:0051050 92 0.019
cellular response to chemical stimulus GO:0070887 199 0.019
cholesterol homeostasis GO:0042632 3 0.019
protein transport GO:0015031 155 0.019
epidermis development GO:0008544 65 0.019
cellular nitrogen compound catabolic process GO:0044270 165 0.019
positive regulation of cell communication GO:0010647 250 0.019
single organism intracellular transport GO:1902582 207 0.019
phosphorylation GO:0016310 294 0.019
cellular lipid metabolic process GO:0044255 83 0.019
camera type eye development GO:0043010 4 0.019
skin development GO:0043588 65 0.019
cellular protein localization GO:0034613 160 0.019
developmental growth GO:0048589 280 0.019
protein localization GO:0008104 284 0.019
apical junction assembly GO:0043297 32 0.019
proteolysis GO:0006508 192 0.019
intracellular protein transmembrane transport GO:0065002 4 0.018
organonitrogen compound catabolic process GO:1901565 128 0.018
lipid metabolic process GO:0006629 121 0.018
regulation of neurotransmitter levels GO:0001505 38 0.018
regulation of cellular localization GO:0060341 136 0.018
aromatic compound catabolic process GO:0019439 166 0.018
cell proliferation GO:0008283 299 0.018
regulation of transport GO:0051049 181 0.018
male gamete generation GO:0048232 201 0.018
multi organism behavior GO:0051705 175 0.018
negative regulation of cellular biosynthetic process GO:0031327 277 0.018
insecticide metabolic process GO:0017143 2 0.018
aging GO:0007568 143 0.018
nicotinamide nucleotide metabolic process GO:0046496 2 0.018
secretion GO:0046903 109 0.018
regulation of intracellular signal transduction GO:1902531 236 0.017
medium chain fatty acid metabolic process GO:0051791 1 0.017
ovarian follicle cell migration GO:0007297 121 0.017
cell adhesion GO:0007155 136 0.017
cellular component assembly involved in morphogenesis GO:0010927 151 0.017
regulation of tube size open tracheal system GO:0035151 43 0.017
response to biotic stimulus GO:0009607 294 0.017
tissue morphogenesis GO:0048729 297 0.017
immune response GO:0006955 246 0.017
negative regulation of biosynthetic process GO:0009890 277 0.017
cell junction organization GO:0034330 57 0.017
oxidation reduction process GO:0055114 123 0.017
epidermal cell differentiation GO:0009913 51 0.016
polyol biosynthetic process GO:0046173 3 0.016
female meiotic division GO:0007143 70 0.016
chaeta development GO:0022416 97 0.016
neutral lipid biosynthetic process GO:0046460 2 0.016
forebrain development GO:0030900 2 0.016
homeostatic process GO:0042592 199 0.016
maintenance of imaginal disc derived wing hair orientation GO:0035321 3 0.016
purine containing compound metabolic process GO:0072521 155 0.016
regulation of multicellular organismal development GO:2000026 414 0.016
regulation of protein metabolic process GO:0051246 256 0.016
response to copper ion GO:0046688 4 0.016
meiotic cell cycle GO:0051321 171 0.016
regulation of cellular amine metabolic process GO:0033238 3 0.016
sulfur compound metabolic process GO:0006790 59 0.016
neurological system process GO:0050877 358 0.016
innate immune response GO:0045087 144 0.016
detection of stimulus GO:0051606 156 0.016
hair cell differentiation GO:0035315 47 0.015
death GO:0016265 284 0.015
cholesterol transport GO:0030301 2 0.015
cellular macromolecule localization GO:0070727 220 0.015
regulation of programmed cell death GO:0043067 152 0.015
ion transport GO:0006811 145 0.015
vitamin metabolic process GO:0006766 2 0.015
peptide metabolic process GO:0006518 80 0.015
triglyceride catabolic process GO:0019433 3 0.015
tube development GO:0035295 244 0.015
body morphogenesis GO:0010171 2 0.015
androgen metabolic process GO:0008209 1 0.015
positive regulation of nitrogen compound metabolic process GO:0051173 354 0.015
sterol homeostasis GO:0055092 4 0.015
regulation of cellular protein metabolic process GO:0032268 243 0.015
cellular modified amino acid metabolic process GO:0006575 45 0.015
establishment of protein localization GO:0045184 163 0.015
regulation of cellular amino acid metabolic process GO:0006521 0 0.015
organic cyclic compound catabolic process GO:1901361 168 0.015
glycerolipid catabolic process GO:0046503 3 0.014
response to alcohol GO:0097305 95 0.014
embryonic morphogenesis GO:0048598 206 0.014
intracellular signal transduction GO:0035556 300 0.014
maintenance of location GO:0051235 73 0.014
macromolecular complex assembly GO:0065003 256 0.014
programmed cell death GO:0012501 257 0.014
sensory perception GO:0007600 196 0.014
nucleotide metabolic process GO:0009117 161 0.014
estrogen metabolic process GO:0008210 1 0.014
response to fungus GO:0009620 50 0.014
positive regulation of signal transduction GO:0009967 223 0.014
cellular response to ethanol GO:0071361 4 0.014
kidney development GO:0001822 3 0.014
establishment of blood nerve barrier GO:0008065 2 0.014
positive regulation of gene expression GO:0010628 290 0.014
meiotic nuclear division GO:0007126 151 0.014
peripheral nervous system development GO:0007422 52 0.014
response to nutrient levels GO:0031667 114 0.014
defense response to bacterium GO:0042742 178 0.014
nucleobase containing compound catabolic process GO:0034655 165 0.014
eye development GO:0001654 323 0.014
macromolecule catabolic process GO:0009057 161 0.014
mesoderm development GO:0007498 78 0.013
connective tissue development GO:0061448 3 0.013
response to ethanol GO:0045471 59 0.013
lipid localization GO:0010876 54 0.013
cell adhesion involved in heart morphogenesis GO:0061343 12 0.013
organonitrogen compound biosynthetic process GO:1901566 117 0.013
negative regulation of nitrogen compound metabolic process GO:0051172 265 0.013
nitrogen compound transport GO:0071705 85 0.013
sensory organ morphogenesis GO:0090596 260 0.013
negative regulation of gene expression GO:0010629 387 0.013
regulation of catalytic activity GO:0050790 185 0.013
encapsulation of foreign target GO:0035010 38 0.013
pigmentation GO:0043473 75 0.013
pyridine nucleotide metabolic process GO:0019362 2 0.013
purine ribonucleoside metabolic process GO:0046128 127 0.013
cellular amide metabolic process GO:0043603 80 0.013
detection of chemical stimulus GO:0009593 93 0.013
protein complex biogenesis GO:0070271 201 0.013
carbohydrate derivative catabolic process GO:1901136 118 0.012
hormone catabolic process GO:0042447 3 0.012
actin filament based process GO:0030029 220 0.012
protein complex assembly GO:0006461 200 0.012
compound eye morphogenesis GO:0001745 249 0.012
gland development GO:0048732 191 0.012
transcription from rna polymerase ii promoter GO:0006366 368 0.012
positive regulation of nucleobase containing compound metabolic process GO:0045935 332 0.012
regulation of phosphorus metabolic process GO:0051174 210 0.012
organic hydroxy compound catabolic process GO:1901616 4 0.012
chemical homeostasis GO:0048878 92 0.012
regulation of tube architecture open tracheal system GO:0035152 68 0.012
positive regulation of cell motility GO:2000147 3 0.012
phosphatidylethanolamine metabolic process GO:0046337 1 0.012
cation transport GO:0006812 110 0.012
regulation of cellular component biogenesis GO:0044087 201 0.012
regulation of lipid transport GO:0032368 3 0.012
intracellular protein transport GO:0006886 104 0.012
immune effector process GO:0002252 98 0.012
regulation of cell differentiation GO:0045595 302 0.012
positive regulation of cell migration GO:0030335 2 0.012
compound eye development GO:0048749 307 0.012
intracellular protein transmembrane import GO:0044743 4 0.012
cellular response to dna damage stimulus GO:0006974 223 0.012
peptidyl amino acid modification GO:0018193 105 0.012
organelle localization GO:0051640 148 0.011
regulation of cell death GO:0010941 173 0.011
adult behavior GO:0030534 137 0.011
cellular response to organic substance GO:0071310 132 0.011
defense response to fungus GO:0050832 48 0.011
regulation of molecular function GO:0065009 217 0.011
regulation of anatomical structure morphogenesis GO:0022603 242 0.011
lipid biosynthetic process GO:0008610 46 0.011
phosphatidic acid metabolic process GO:0046473 1 0.011
embryonic development via the syncytial blastoderm GO:0001700 148 0.011
glycosyl compound metabolic process GO:1901657 127 0.011
wound healing GO:0042060 75 0.011
positive regulation of rna biosynthetic process GO:1902680 266 0.011
mitotic nuclear division GO:0007067 213 0.011
response to extracellular stimulus GO:0009991 116 0.011
dna metabolic process GO:0006259 227 0.011
morphogenesis of an epithelium GO:0002009 276 0.011
regulation of catabolic process GO:0009894 170 0.011
meiotic cell cycle process GO:1903046 132 0.011
glutathione metabolic process GO:0006749 37 0.011
vitamin biosynthetic process GO:0009110 1 0.011
energy taxis GO:0009453 21 0.011
monocarboxylic acid transport GO:0015718 3 0.011
regulation of cell cycle process GO:0010564 181 0.011
neutral lipid catabolic process GO:0046461 3 0.011
response to nitrogen compound GO:1901698 90 0.011
salivary gland morphogenesis GO:0007435 145 0.011
response to starvation GO:0042594 97 0.011
purine nucleoside catabolic process GO:0006152 112 0.011
g protein coupled receptor signaling pathway GO:0007186 136 0.011
single organism carbohydrate metabolic process GO:0044723 72 0.011
cellular macromolecule catabolic process GO:0044265 136 0.011
cell cell junction assembly GO:0007043 38 0.011
purine nucleoside metabolic process GO:0042278 127 0.011
negative regulation of nucleobase containing compound metabolic process GO:0045934 261 0.010
digestive system development GO:0055123 149 0.010
organophosphate catabolic process GO:0046434 112 0.010
tube morphogenesis GO:0035239 191 0.010
regulation of phosphate metabolic process GO:0019220 210 0.010
positive regulation of catalytic activity GO:0043085 118 0.010
cytoplasmic transport GO:0016482 130 0.010
purine ribonucleoside catabolic process GO:0046130 112 0.010
apoptotic process GO:0006915 159 0.010
regulation of transcription from rna polymerase ii promoter GO:0006357 378 0.010
eggshell chorion assembly GO:0007306 66 0.010
benzene containing compound metabolic process GO:0042537 3 0.010
multi multicellular organism process GO:0044706 123 0.010
cellularization GO:0007349 90 0.010
response to organic cyclic compound GO:0014070 89 0.010
cell cell junction organization GO:0045216 55 0.010
nucleoside catabolic process GO:0009164 112 0.010
ribonucleoside metabolic process GO:0009119 127 0.010
ribonucleoside catabolic process GO:0042454 112 0.010

alpha-Est5 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in fly and predicted with the fly functional network.

Disease DO term ID Size Probability Func Analog Org
disease of anatomical entity DOID:7 0 0.029
disease of metabolism DOID:0014667 0 0.027
diabetes mellitus DOID:9351 0 0.023
carbohydrate metabolism disease DOID:0050013 0 0.023
glucose metabolism disease DOID:4194 0 0.023
acquired metabolic disease DOID:0060158 0 0.023
inherited metabolic disorder DOID:655 0 0.023
familial hyperlipidemia DOID:1168 0 0.022
familial combined hyperlipidemia DOID:13809 0 0.022
lipid metabolism disorder DOID:3146 0 0.022
type 2 diabetes mellitus DOID:9352 0 0.020
familial hypertriglyceridemia DOID:0050527 0 0.019
nervous system disease DOID:863 0 0.015
cardiovascular system disease DOID:1287 0 0.014
artery disease DOID:0050828 0 0.012
vascular disease DOID:178 0 0.012
central nervous system disease DOID:331 0 0.011
hypotrichosis DOID:4535 0 0.010
integumentary system disease DOID:16 0 0.010
hair disease DOID:421 0 0.010