Drosophila melanogaster

92 known processes

amn (Dmel_CG11937)

amnesiac

(Aliases: Pacap38,PACAP,Amn,PACAP-38,PACAP38,EP(X)1442,PACAP38-like,CG11937,chpd,Drm-amn,Dmel\CG11937,PACAP-like)

amn biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
neurological system process GO:0050877 358 0.999
single organism behavior GO:0044708 391 0.998
learning or memory GO:0007611 141 0.990
olfactory behavior GO:0042048 97 0.957
detection of stimulus involved in sensory perception GO:0050906 92 0.932
cognition GO:0050890 141 0.876
learning GO:0007612 75 0.740
thermotaxis GO:0043052 16 0.661
sensory perception GO:0007600 196 0.592
cation transport GO:0006812 110 0.510
locomotory behavior GO:0007626 176 0.371
chemosensory behavior GO:0007635 106 0.348
g protein coupled receptor signaling pathway GO:0007186 136 0.314
inter male aggressive behavior GO:0002121 60 0.295
long term memory GO:0007616 62 0.288
memory GO:0007613 94 0.270
imaginal disc derived appendage morphogenesis GO:0035114 395 0.243
cell motility GO:0048870 251 0.229
localization of cell GO:0051674 257 0.220
synapse organization GO:0050808 196 0.220
central nervous system development GO:0007417 201 0.219
regulation of synaptic growth at neuromuscular junction GO:0008582 89 0.199
response to temperature stimulus GO:0009266 106 0.193
head development GO:0060322 135 0.190
regulation of protein metabolic process GO:0051246 256 0.183
regulation of cellular component biogenesis GO:0044087 201 0.167
sensory perception of chemical stimulus GO:0007606 116 0.166
regulation of immune system process GO:0002682 176 0.162
appendage development GO:0048736 401 0.160
intraspecies interaction between organisms GO:0051703 4 0.158
courtship behavior GO:0007619 68 0.145
gliogenesis GO:0042063 80 0.143
synaptic transmission GO:0007268 288 0.139
positive regulation of cellular component biogenesis GO:0044089 80 0.139
mushroom body development GO:0016319 70 0.137
regulation of synapse structure and activity GO:0050803 128 0.136
synapse assembly GO:0007416 143 0.134
positive regulation of nucleobase containing compound metabolic process GO:0045935 332 0.129
regulation of synaptic transmission GO:0050804 69 0.125
salivary gland development GO:0007431 162 0.118
behavioral response to ethanol GO:0048149 49 0.115
wing disc morphogenesis GO:0007472 344 0.113
associative learning GO:0008306 65 0.112
regulation of system process GO:0044057 36 0.109
medium term memory GO:0072375 8 0.109
regulation of catalytic activity GO:0050790 185 0.104
sensory perception of smell GO:0007608 80 0.103
regulation of phosphorus metabolic process GO:0051174 210 0.102
multi organism behavior GO:0051705 175 0.101
appendage morphogenesis GO:0035107 397 0.100
regulation of olfactory learning GO:0090328 8 0.098
negative regulation of phosphorylation GO:0042326 35 0.096
positive regulation of multicellular organismal process GO:0051240 143 0.096
positive regulation of biosynthetic process GO:0009891 316 0.094
positive regulation of cellular component organization GO:0051130 156 0.094
cellular response to chemical stimulus GO:0070887 199 0.094
negative regulation of cellular protein metabolic process GO:0032269 85 0.092
positive regulation of nitrogen compound metabolic process GO:0051173 354 0.090
response to anesthetic GO:0072347 9 0.090
response to wounding GO:0009611 94 0.084
regulation of meiosis GO:0040020 3 0.084
protein kinase a signaling GO:0010737 2 0.083
cell migration GO:0016477 238 0.083
synaptic growth at neuromuscular junction GO:0051124 119 0.082
negative regulation of calcium ion import GO:0090281 2 0.081
positive regulation of immune response GO:0050778 63 0.079
neuromuscular junction development GO:0007528 149 0.079
negative regulation of response to stimulus GO:0048585 258 0.076
regulation of multicellular organismal development GO:2000026 414 0.076
detection of chemical stimulus GO:0009593 93 0.076
post embryonic appendage morphogenesis GO:0035120 385 0.076
nucleobase containing compound catabolic process GO:0034655 165 0.075
conditioned taste aversion GO:0001661 3 0.074
immune response activating signal transduction GO:0002757 2 0.073
male courtship behavior GO:0008049 63 0.069
detection of stimulus GO:0051606 156 0.069
intracellular signal transduction GO:0035556 300 0.068
male courtship behavior veined wing generated song production GO:0045433 20 0.067
response to organic substance GO:0010033 284 0.067
cellular amino acid metabolic process GO:0006520 61 0.062
positive regulation of catalytic activity GO:0043085 118 0.061
macromolecular complex assembly GO:0065003 256 0.061
negative regulation of synaptic growth at neuromuscular junction GO:0045886 39 0.060
regulation of cell cycle process GO:0010564 181 0.059
aggressive behavior GO:0002118 63 0.059
organonitrogen compound metabolic process GO:1901564 318 0.059
regulation of synapse organization GO:0050807 110 0.059
molting cycle chitin based cuticle GO:0007591 56 0.058
organic substance catabolic process GO:1901575 308 0.058
dendrite development GO:0016358 204 0.057
response to mechanical stimulus GO:0009612 28 0.056
brain development GO:0007420 120 0.055
small molecule metabolic process GO:0044281 305 0.055
anesthesia resistant memory GO:0007615 6 0.055
response to oxidative stress GO:0006979 86 0.054
regulation of immune response GO:0050776 118 0.054
social behavior GO:0035176 4 0.052
adult behavior GO:0030534 137 0.052
cellular catabolic process GO:0044248 372 0.051
negative regulation of cellular metabolic process GO:0031324 382 0.051
axon extension GO:0048675 32 0.049
detection of chemical stimulus involved in sensory perception of smell GO:0050911 50 0.049
regulation of mitotic cell cycle phase transition GO:1901990 130 0.048
exocrine system development GO:0035272 162 0.047
heart process GO:0003015 37 0.047
response to oxygen containing compound GO:1901700 200 0.046
developmental cell growth GO:0048588 52 0.046
metal ion transport GO:0030001 74 0.046
regulation of transmembrane transport GO:0034762 27 0.045
immune response regulating signaling pathway GO:0002764 2 0.045
immune system process GO:0002376 347 0.044
positive regulation of axon guidance GO:1902669 1 0.044
imaginal disc derived appendage development GO:0048737 399 0.044
protein heterooligomerization GO:0051291 4 0.043
regulation of molecular function GO:0065009 217 0.043
regulation of cell substrate adhesion GO:0010810 2 0.043
reproductive behavior GO:0019098 122 0.042
neuropeptide signaling pathway GO:0007218 45 0.042
sensory perception of touch GO:0050975 11 0.042
positive regulation of signaling GO:0023056 243 0.041
sensory perception of mechanical stimulus GO:0050954 72 0.040
regulation of synapse assembly GO:0051963 94 0.040
nucleobase containing small molecule metabolic process GO:0055086 174 0.040
purine ribonucleotide metabolic process GO:0009150 145 0.040
positive regulation of synapse assembly GO:0051965 29 0.039
morphogenesis of an epithelium GO:0002009 276 0.039
regulation of response to stress GO:0080134 200 0.039
positive regulation of developmental process GO:0051094 143 0.039
formation of organ boundary GO:0010160 30 0.039
positive regulation of cellular catabolic process GO:0031331 95 0.038
cellular nitrogen compound catabolic process GO:0044270 165 0.038
developmental maturation GO:0021700 172 0.038
imaginal disc derived wing morphogenesis GO:0007476 337 0.037
single organism intracellular transport GO:1902582 207 0.037
blood circulation GO:0008015 26 0.037
negative regulation of nervous system development GO:0051961 92 0.037
phagocytosis GO:0006909 215 0.037
respiratory system development GO:0060541 213 0.036
macromolecule catabolic process GO:0009057 161 0.036
negative regulation of signaling GO:0023057 219 0.036
rhythmic behavior GO:0007622 76 0.036
oocyte maturation GO:0001556 3 0.035
regulation of organelle organization GO:0033043 196 0.035
regulation of cellular catabolic process GO:0031329 157 0.035
response to abiotic stimulus GO:0009628 341 0.034
protein complex assembly GO:0006461 200 0.034
regulation of developmental growth GO:0048638 174 0.034
carboxylic acid metabolic process GO:0019752 92 0.034
circadian behavior GO:0048512 76 0.034
circulatory system process GO:0003013 37 0.034
positive regulation of cellular amino acid metabolic process GO:0045764 0 0.034
transmembrane transport GO:0055085 139 0.034
organelle fission GO:0048285 340 0.033
response to hypoxia GO:0001666 53 0.033
regulation of cell division GO:0051302 72 0.032
positive regulation of molecular function GO:0044093 136 0.032
positive regulation of cell communication GO:0010647 250 0.032
male mating behavior GO:0060179 70 0.032
regulation of blood circulation GO:1903522 21 0.031
negative regulation of protein metabolic process GO:0051248 85 0.031
regulation of cell cycle GO:0051726 291 0.030
mrna catabolic process GO:0006402 33 0.030
forebrain development GO:0030900 2 0.030
positive regulation of nucleic acid templated transcription GO:1903508 266 0.030
taxis GO:0042330 304 0.030
cell division GO:0051301 248 0.030
inorganic ion transmembrane transport GO:0098660 73 0.030
proteolysis GO:0006508 192 0.030
intracellular transport GO:0046907 228 0.029
ribonucleotide metabolic process GO:0009259 145 0.029
regulation of cellular ketone metabolic process GO:0010565 3 0.029
positive regulation of macromolecule biosynthetic process GO:0010557 283 0.029
ion transport GO:0006811 145 0.029
regulation of localization GO:0032879 275 0.029
nucleotide metabolic process GO:0009117 161 0.028
embryonic heart tube development GO:0035050 22 0.028
catabolic process GO:0009056 409 0.028
short term memory GO:0007614 19 0.028
positive regulation of rna biosynthetic process GO:1902680 266 0.027
regulation of circadian rhythm GO:0042752 49 0.027
cellular macromolecule localization GO:0070727 220 0.027
endocytosis GO:0006897 310 0.027
open tracheal system development GO:0007424 204 0.027
response to starvation GO:0042594 97 0.027
regulation of nuclear division GO:0051783 58 0.027
skin development GO:0043588 65 0.026
response to decreased oxygen levels GO:0036293 58 0.026
neuroblast proliferation GO:0007405 74 0.026
dopamine biosynthetic process GO:0042416 3 0.026
cell death GO:0008219 279 0.026
regulation of ion transport GO:0043269 39 0.026
primary amino compound biosynthetic process GO:1901162 2 0.026
neuron recognition GO:0008038 101 0.026
regulation of intracellular signal transduction GO:1902531 236 0.025
cell fate determination GO:0001709 91 0.025
regulation of catabolic process GO:0009894 170 0.025
negative regulation of protein modification process GO:0031400 29 0.025
purine containing compound metabolic process GO:0072521 155 0.025
calcium ion transport GO:0006816 24 0.025
oxoacid metabolic process GO:0043436 103 0.025
signal transduction by phosphorylation GO:0023014 107 0.024
positive regulation of synaptic growth at neuromuscular junction GO:0045887 26 0.024
heart contraction GO:0060047 26 0.024
positive regulation of macromolecule metabolic process GO:0010604 405 0.024
imaginal disc pattern formation GO:0007447 91 0.024
positive regulation of response to external stimulus GO:0032103 44 0.024
neuron projection extension GO:1990138 32 0.024
regulation of cellular amino acid metabolic process GO:0006521 0 0.024
single organism catabolic process GO:0044712 228 0.024
negative regulation of gene expression GO:0010629 387 0.024
negative regulation of cell communication GO:0010648 223 0.023
regulation of cellular protein metabolic process GO:0032268 243 0.023
epidermal cell differentiation GO:0009913 51 0.023
posttranscriptional gene silencing by rna GO:0035194 45 0.023
purine nucleotide metabolic process GO:0006163 146 0.023
regulation of glial cell proliferation GO:0060251 11 0.023
positive regulation of cellular amine metabolic process GO:0033240 0 0.023
positive regulation of signal transduction GO:0009967 223 0.022
mitotic cell cycle phase transition GO:0044772 138 0.022
organic acid metabolic process GO:0006082 103 0.022
negative regulation of neural precursor cell proliferation GO:2000178 27 0.022
mating GO:0007618 120 0.022
negative regulation of neuroblast proliferation GO:0007406 27 0.022
telencephalon development GO:0021537 2 0.022
regulation of transcription from rna polymerase ii promoter GO:0006357 378 0.022
ribonucleoside triphosphate metabolic process GO:0009199 119 0.021
regulation of cellular amine metabolic process GO:0033238 3 0.021
negative regulation of growth GO:0045926 84 0.021
positive regulation of gene expression GO:0010628 290 0.021
posttranscriptional regulation of gene expression GO:0010608 145 0.021
purine ribonucleoside metabolic process GO:0046128 127 0.021
cyclic nucleotide metabolic process GO:0009187 28 0.020
enzyme linked receptor protein signaling pathway GO:0007167 179 0.020
regulation of anatomical structure size GO:0090066 163 0.020
regulation of nervous system development GO:0051960 248 0.020
adenylate cyclase modulating g protein coupled receptor signaling pathway GO:0007188 17 0.020
aromatic compound catabolic process GO:0019439 166 0.020
posttranscriptional gene silencing GO:0016441 46 0.020
positive regulation of intracellular signal transduction GO:1902533 116 0.020
startle response GO:0001964 16 0.020
growth GO:0040007 359 0.020
axon target recognition GO:0007412 16 0.019
cyclic nucleotide biosynthetic process GO:0009190 25 0.019
transcription from rna polymerase ii promoter GO:0006366 368 0.019
positive regulation of neurotransmitter secretion GO:0001956 2 0.019
regulation of protein kinase activity GO:0045859 51 0.019
adult walking behavior GO:0007628 9 0.019
sensory organ precursor cell fate determination GO:0016360 19 0.019
regulation of epithelial cell proliferation GO:0050678 4 0.019
negative regulation of neurogenesis GO:0050768 53 0.019
establishment of localization in cell GO:0051649 402 0.019
organophosphate metabolic process GO:0019637 195 0.019
positive regulation of phosphorus metabolic process GO:0010562 139 0.019
cell cycle phase transition GO:0044770 140 0.019
axon development GO:0061564 297 0.019
presynaptic membrane organization GO:0097090 4 0.019
positive regulation of cell migration GO:0030335 2 0.019
regulation of protein phosphorylation GO:0001932 64 0.019
cellular response to dna damage stimulus GO:0006974 223 0.019
age dependent general metabolic decline GO:0007571 3 0.019
regionalization GO:0003002 416 0.018
nucleotide biosynthetic process GO:0009165 34 0.018
carbohydrate derivative metabolic process GO:1901135 217 0.018
epidermis development GO:0008544 65 0.018
regulation of heart contraction GO:0008016 21 0.018
chromosome organization GO:0051276 360 0.018
extrinsic apoptotic signaling pathway GO:0097191 1 0.018
camera type eye morphogenesis GO:0048593 2 0.018
positive regulation of phosphate metabolic process GO:0045937 139 0.018
response to nitrogen compound GO:1901698 90 0.017
negative regulation of cellular component organization GO:0051129 108 0.017
negative regulation of developmental process GO:0051093 201 0.017
male courtship behavior veined wing extension GO:0048065 22 0.017
apoptotic process GO:0006915 159 0.017
multi multicellular organism process GO:0044706 123 0.017
developmental growth GO:0048589 280 0.017
positive regulation of protein complex assembly GO:0031334 22 0.017
nucleoside phosphate metabolic process GO:0006753 162 0.017
positive regulation of response to stimulus GO:0048584 323 0.017
cellular response to oxygen containing compound GO:1901701 79 0.017
cell recognition GO:0008037 102 0.017
regulation of protein modification process GO:0031399 112 0.017
regulation of proteolysis GO:0030162 87 0.017
cranial nerve development GO:0021545 1 0.017
cytoplasmic transport GO:0016482 130 0.016
regulation of neuroblast proliferation GO:1902692 34 0.016
transmission of nerve impulse GO:0019226 12 0.016
cellular response to carbohydrate stimulus GO:0071322 4 0.016
vesicle mediated transport GO:0016192 381 0.016
response to oxygen levels GO:0070482 59 0.016
regulation of hydrolase activity GO:0051336 97 0.016
habituation GO:0046959 10 0.016
regulation of synaptic plasticity GO:0048167 14 0.016
phosphorylation GO:0016310 294 0.016
neuron neuron synaptic transmission GO:0007270 14 0.016
protein complex biogenesis GO:0070271 201 0.016
rna catabolic process GO:0006401 37 0.016
dendrite morphogenesis GO:0048813 199 0.016
adult locomotory behavior GO:0008344 76 0.016
regulation of apoptotic process GO:0042981 130 0.016
response to alcohol GO:0097305 95 0.016
serotonin metabolic process GO:0042428 2 0.015
membrane depolarization GO:0051899 4 0.015
protein localization GO:0008104 284 0.015
detection of mechanical stimulus GO:0050982 6 0.015
regulation of purine nucleotide biosynthetic process GO:1900371 14 0.015
regulation of cell matrix adhesion GO:0001952 1 0.015
regulation of behavior GO:0050795 75 0.015
regulation of protein localization GO:0032880 76 0.015
positive regulation of immune system process GO:0002684 68 0.015
response to heat GO:0009408 63 0.015
ribose phosphate metabolic process GO:0019693 145 0.015
cellular protein localization GO:0034613 160 0.015
central complex development GO:0048036 9 0.015
regulation of growth GO:0040008 233 0.015
chromatin modification GO:0016568 147 0.015
positive regulation of epithelial cell differentiation GO:0030858 1 0.015
protein transmembrane transport GO:0071806 4 0.015
camp metabolic process GO:0046058 19 0.015
regulation of response to external stimulus GO:0032101 115 0.015
germ cell migration GO:0008354 43 0.015
inositol lipid mediated signaling GO:0048017 4 0.015
protein targeting to nucleus GO:0044744 51 0.015
spinal cord development GO:0021510 1 0.015
positive regulation of nervous system development GO:0051962 69 0.014
ribonucleotide biosynthetic process GO:0009260 28 0.014
nucleoside triphosphate metabolic process GO:0009141 120 0.014
anterior posterior pattern specification GO:0009952 136 0.014
rna processing GO:0006396 147 0.014
erbb signaling pathway GO:0038127 58 0.014
positive regulation of purine nucleotide metabolic process GO:1900544 55 0.014
regulation of transport GO:0051049 181 0.014
nucleoside phosphate biosynthetic process GO:1901293 34 0.014
salivary gland morphogenesis GO:0007435 145 0.014
amine metabolic process GO:0009308 12 0.014
negative regulation of synapse assembly GO:0051964 39 0.014
negative regulation of cell proliferation GO:0008285 69 0.014
olfactory learning GO:0008355 56 0.014
renal system development GO:0072001 72 0.014
regulation of membrane potential GO:0042391 35 0.014
wound healing GO:0042060 75 0.014
response to organonitrogen compound GO:0010243 75 0.014
establishment of protein localization GO:0045184 163 0.014
regulation of cell death GO:0010941 173 0.013
sensory perception of pain GO:0019233 4 0.013
organonitrogen compound biosynthetic process GO:1901566 117 0.013
transmembrane receptor protein serine threonine kinase signaling pathway GO:0007178 65 0.013
negative regulation of transcription from rna polymerase ii promoter GO:0000122 119 0.013
positive regulation of transcription dna templated GO:0045893 266 0.013
cellular ketone metabolic process GO:0042180 24 0.013
cellular homeostasis GO:0019725 80 0.013
cellular amine metabolic process GO:0044106 12 0.013
protein transport GO:0015031 155 0.013
negative regulation of protein phosphorylation GO:0001933 17 0.013
positive regulation of apoptotic signaling pathway GO:2001235 4 0.013
kidney epithelium development GO:0072073 3 0.013
single organism cell adhesion GO:0098602 47 0.013
ion transmembrane transport GO:0034220 122 0.013
feeding behavior GO:0007631 50 0.013
negative regulation of stem cell proliferation GO:2000647 30 0.013
regulation of endopeptidase activity GO:0052548 36 0.013
positive regulation of endopeptidase activity GO:0010950 26 0.013
regulation of transferase activity GO:0051338 58 0.013
positive regulation of synaptic transmission glutamatergic GO:0051968 3 0.012
glial cell differentiation GO:0010001 35 0.012
negative regulation of cell differentiation GO:0045596 143 0.012
negative regulation of developmental growth GO:0048640 64 0.012
operant conditioning GO:0035106 2 0.012
catecholamine biosynthetic process GO:0042423 3 0.012
regulation of dendrite development GO:0050773 37 0.012
cellular response to organic cyclic compound GO:0071407 32 0.012
dorsal ventral pattern formation imaginal disc GO:0007450 51 0.012
regulation of programmed cell death GO:0043067 152 0.012
multi organism reproductive behavior GO:0044705 121 0.012
regulation of phosphate metabolic process GO:0019220 210 0.012
regulation of cell cycle phase transition GO:1901987 130 0.012
negative regulation of multicellular organismal process GO:0051241 142 0.012
single organism cellular localization GO:1902580 180 0.012
camera type eye development GO:0043010 4 0.012
transmembrane receptor protein tyrosine kinase signaling pathway GO:0007169 116 0.012
positive regulation of cell motility GO:2000147 3 0.012
nephron tubule development GO:0072080 3 0.012
positive regulation of rna metabolic process GO:0051254 271 0.012
regulation of gene expression epigenetic GO:0040029 128 0.012
negative regulation of transferase activity GO:0051348 18 0.012
cellular macromolecule catabolic process GO:0044265 136 0.012
developmental growth involved in morphogenesis GO:0060560 65 0.012
limb morphogenesis GO:0035108 1 0.012
dna methylation or demethylation GO:0044728 4 0.011
protein phosphorylation GO:0006468 169 0.011
nephron development GO:0072006 3 0.011
negative regulation of kinase activity GO:0033673 16 0.011
negative regulation of nitrogen compound metabolic process GO:0051172 265 0.011
cell proliferation GO:0008283 299 0.011
molting cycle GO:0042303 56 0.011
protein maturation GO:0051604 71 0.011
phosphatidylinositol 3 kinase signaling GO:0014065 4 0.011
intercellular transport GO:0010496 2 0.011
small gtpase mediated signal transduction GO:0007264 88 0.011
regulation of nucleotide metabolic process GO:0006140 62 0.011
signal transduction in response to dna damage GO:0042770 3 0.011
positive regulation of cyclic nucleotide biosynthetic process GO:0030804 9 0.011
single organism biosynthetic process GO:0044711 206 0.011
calcium ion transport into cytosol GO:0060402 2 0.011
smoothened signaling pathway GO:0007224 49 0.011
lipid metabolic process GO:0006629 121 0.011
hematopoietic or lymphoid organ development GO:0048534 57 0.011
regulation of phosphorylation GO:0042325 147 0.011
regulation of cytoplasmic transport GO:1903649 47 0.011
positive regulation of cyclic nucleotide metabolic process GO:0030801 9 0.011
negative regulation of macromolecule biosynthetic process GO:0010558 270 0.011
protein processing GO:0016485 68 0.011
negative regulation of phosphorus metabolic process GO:0010563 45 0.011
regulation of neuron projection development GO:0010975 69 0.011
cellular response to transforming growth factor beta stimulus GO:0071560 18 0.011
aging GO:0007568 143 0.011
urogenital system development GO:0001655 72 0.011
regulation of vesicle mediated transport GO:0060627 59 0.011
regulation of protein complex assembly GO:0043254 42 0.010
germarium derived female germ line cyst formation GO:0030727 42 0.010
cellular macromolecular complex assembly GO:0034622 153 0.010
nonassociative learning GO:0046958 11 0.010
regulation of nucleocytoplasmic transport GO:0046822 35 0.010
negative regulation of transcription dna templated GO:0045892 237 0.010
negative regulation of meiotic cell cycle GO:0051447 2 0.010
axonogenesis GO:0007409 290 0.010
nucleocytoplasmic transport GO:0006913 72 0.010
hair cell differentiation GO:0035315 47 0.010

amn disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in fly and predicted with the fly functional network.

Disease DO term ID Size Probability Func Analog Org
disease of anatomical entity DOID:7 0 0.108
urinary system disease DOID:18 0 0.050
cancer DOID:162 0 0.026
disease of cellular proliferation DOID:14566 0 0.026
kidney disease DOID:557 0 0.013
respiratory system disease DOID:1579 0 0.012