Drosophila melanogaster

104 known processes

hipk (Dmel_CG17090)

homeodomain interacting protein kinase

(Aliases: CG17090,dhipk2,HIPK,Dmel\CG17090)

hipk biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
eye development GO:0001654 323 0.993
imaginal disc derived appendage development GO:0048737 399 0.992
appendage development GO:0048736 401 0.976
compound eye development GO:0048749 307 0.962
eye morphogenesis GO:0048592 260 0.962
Mouse
imaginal disc derived wing morphogenesis GO:0007476 337 0.945
imaginal disc derived appendage morphogenesis GO:0035114 395 0.921
negative regulation of signal transduction GO:0009968 206 0.918
Human Mouse
appendage morphogenesis GO:0035107 397 0.916
taxis GO:0042330 304 0.877
sensory organ morphogenesis GO:0090596 260 0.867
Mouse
heart development GO:0007507 82 0.852
wing disc morphogenesis GO:0007472 344 0.831
negative regulation of cellular biosynthetic process GO:0031327 277 0.811
Human Mouse
compound eye morphogenesis GO:0001745 249 0.802
post embryonic appendage morphogenesis GO:0035120 385 0.799
regionalization GO:0003002 416 0.797
Mouse
negative regulation of gene expression GO:0010629 387 0.796
Mouse
regulation of transcription from rna polymerase ii promoter GO:0006357 378 0.774
Human Mouse
negative regulation of cellular macromolecule biosynthetic process GO:2000113 267 0.762
Mouse
morphogenesis of an epithelium GO:0002009 276 0.749
synapse organization GO:0050808 196 0.740
positive regulation of cellular biosynthetic process GO:0031328 316 0.732
Human Mouse
phosphorylation GO:0016310 294 0.693
transmembrane receptor protein tyrosine kinase signaling pathway GO:0007169 116 0.653
positive regulation of nitrogen compound metabolic process GO:0051173 354 0.644
Human Mouse
regulation of cell proliferation GO:0042127 163 0.642
Mouse
regulation of protein metabolic process GO:0051246 256 0.641
Mouse
synapse assembly GO:0007416 143 0.639
negative regulation of nucleobase containing compound metabolic process GO:0045934 261 0.629
Human Mouse
enzyme linked receptor protein signaling pathway GO:0007167 179 0.608
Human Mouse
regulation of phosphorylation GO:0042325 147 0.600
Human Mouse
positive regulation of gene expression GO:0010628 290 0.600
Human Mouse
negative regulation of nucleic acid templated transcription GO:1903507 240 0.598
Human Mouse
protein phosphorylation GO:0006468 169 0.593
positive regulation of rna metabolic process GO:0051254 271 0.575
Human Mouse
eye photoreceptor cell differentiation GO:0001754 145 0.574
axonogenesis GO:0007409 290 0.564
negative regulation of response to stimulus GO:0048585 258 0.549
Human Mouse
cellular response to chemical stimulus GO:0070887 199 0.541
Human Mouse
regulation of erbb signaling pathway GO:1901184 42 0.537
regulation of cell cycle GO:0051726 291 0.522
compound eye photoreceptor cell differentiation GO:0001751 140 0.511
positive regulation of phosphate metabolic process GO:0045937 139 0.503
Human Mouse
response to abiotic stimulus GO:0009628 341 0.495
regulation of synapse structure and activity GO:0050803 128 0.488
establishment or maintenance of cell polarity GO:0007163 167 0.487
negative regulation of cell communication GO:0010648 223 0.476
Human Mouse
developmental growth GO:0048589 280 0.474
positive regulation of cell migration GO:0030335 2 0.473
embryonic development via the syncytial blastoderm GO:0001700 148 0.454
localization of cell GO:0051674 257 0.439
response to organic substance GO:0010033 284 0.437
Human Mouse
response to gravity GO:0009629 26 0.430
epithelial cell differentiation GO:0030855 322 0.424
Zebrafish
single organism cellular localization GO:1902580 180 0.424
biological adhesion GO:0022610 138 0.423
cell migration GO:0016477 238 0.418
positive regulation of molecular function GO:0044093 136 0.411
Mouse
compound eye photoreceptor development GO:0042051 78 0.398
intracellular transport GO:0046907 228 0.397
negative regulation of macromolecule biosynthetic process GO:0010558 270 0.396
Human Mouse
catabolic process GO:0009056 409 0.391
detection of stimulus GO:0051606 156 0.389
photoreceptor cell differentiation GO:0046530 170 0.380
positive regulation of macromolecule metabolic process GO:0010604 405 0.376
Human Mouse
regulation of intracellular signal transduction GO:1902531 236 0.374
wnt signaling pathway GO:0016055 98 0.372
ameboidal type cell migration GO:0001667 151 0.372
defense response GO:0006952 300 0.368
single organism intracellular transport GO:1902582 207 0.367
lateral inhibition GO:0046331 206 0.367
regulation of cellular protein metabolic process GO:0032268 243 0.353
Mouse
tissue morphogenesis GO:0048729 297 0.351
Mouse
heterocycle catabolic process GO:0046700 166 0.351
negative regulation of transcription from rna polymerase ii promoter GO:0000122 119 0.348
Mouse
imaginal disc derived wing margin morphogenesis GO:0008587 41 0.347
cellular protein modification process GO:0006464 438 0.339
positive regulation of nucleic acid templated transcription GO:1903508 266 0.334
Human Mouse
positive regulation of response to stimulus GO:0048584 323 0.329
spermatid differentiation GO:0048515 114 0.329
reproductive system development GO:0061458 74 0.327
regulation of cell death GO:0010941 173 0.325
growth GO:0040007 359 0.322
death GO:0016265 284 0.317
hematopoietic or lymphoid organ development GO:0048534 57 0.316
embryonic morphogenesis GO:0048598 206 0.315
Mouse
positive regulation of rna biosynthetic process GO:1902680 266 0.309
Human Mouse
neurological system process GO:0050877 358 0.303
immune system process GO:0002376 347 0.299
regulation of wnt signaling pathway GO:0030111 68 0.299
dorsal ventral pattern formation GO:0009953 133 0.296
positive regulation of macromolecule biosynthetic process GO:0010557 283 0.295
Human Mouse
cell death GO:0008219 279 0.290
axon midline choice point recognition GO:0016199 26 0.286
negative regulation of signaling GO:0023057 219 0.285
Human Mouse
regulation of epidermal growth factor receptor signaling pathway GO:0042058 42 0.278
single organismal cell cell adhesion GO:0016337 45 0.275
regulation of nervous system development GO:0051960 248 0.274
asymmetric stem cell division GO:0098722 49 0.274
cell proliferation GO:0008283 299 0.273
Mouse
negative regulation of wnt signaling pathway GO:0030178 28 0.273
regulation of programmed cell death GO:0043067 152 0.273
forebrain development GO:0030900 2 0.273
apoptotic process GO:0006915 159 0.272
Human Mouse
morphogenesis of a polarized epithelium GO:0001738 93 0.270
regulation of protein modification process GO:0031399 112 0.268
Mouse
positive regulation of transcription dna templated GO:0045893 266 0.264
Human Mouse
establishment of cell polarity GO:0030010 40 0.264
circulatory system development GO:0072359 82 0.261
Human
cellular macromolecule catabolic process GO:0044265 136 0.261
regulation of molecular function GO:0065009 217 0.260
Mouse
imaginal disc derived wing vein morphogenesis GO:0008586 44 0.258
r7 cell differentiation GO:0045466 43 0.257
regulation of synaptic growth at neuromuscular junction GO:0008582 89 0.251
skin development GO:0043588 65 0.250
negative regulation of intracellular signal transduction GO:1902532 57 0.247
Mouse
cytoplasmic transport GO:0016482 130 0.244
intracellular protein transport GO:0006886 104 0.243
axon development GO:0061564 297 0.239
immune system development GO:0002520 57 0.239
positive regulation of cell motility GO:2000147 3 0.236
actin filament based process GO:0030029 220 0.236
response to biotic stimulus GO:0009607 294 0.236
cellularization GO:0007349 90 0.233
actin cytoskeleton organization GO:0030036 206 0.227
posttranscriptional regulation of gene expression GO:0010608 145 0.226
regulation of mapk cascade GO:0043408 92 0.224
Human Mouse
negative regulation of epidermal growth factor receptor signaling pathway GO:0042059 29 0.224
regulation of response to stress GO:0080134 200 0.220
Human Mouse
erbb signaling pathway GO:0038127 58 0.208
immune response GO:0006955 246 0.207
wing disc pattern formation GO:0035222 66 0.207
epithelial cell migration GO:0010631 148 0.207
epidermis development GO:0008544 65 0.205
intracellular signal transduction GO:0035556 300 0.202
vesicle mediated transport GO:0016192 381 0.201
regulation of cell differentiation GO:0045595 302 0.201
Zebrafish
epidermal growth factor receptor signaling pathway GO:0007173 58 0.199
signal transduction by phosphorylation GO:0023014 107 0.199
Human Mouse
regulation of system process GO:0044057 36 0.197
regulation of neurogenesis GO:0050767 158 0.196
cell motility GO:0048870 251 0.194
response to other organism GO:0051707 293 0.193
kidney epithelium development GO:0072073 3 0.193
cellular catabolic process GO:0044248 372 0.190
tissue migration GO:0090130 155 0.190
cell adhesion GO:0007155 136 0.189
synaptic growth at neuromuscular junction GO:0051124 119 0.188
eye photoreceptor cell development GO:0042462 81 0.185
regulation of cell motility GO:2000145 23 0.183
negative regulation of transcription dna templated GO:0045892 237 0.183
Mouse
macromolecule catabolic process GO:0009057 161 0.181
regulation of gene expression epigenetic GO:0040029 128 0.180
carboxylic acid metabolic process GO:0019752 92 0.179
ras protein signal transduction GO:0007265 88 0.172
organic substance transport GO:0071702 257 0.171
regulation of mitotic cell cycle GO:0007346 190 0.171
positive regulation of phosphorus metabolic process GO:0010562 139 0.171
Human Mouse
protein modification process GO:0036211 438 0.171
regulation of epithelial cell migration GO:0010632 12 0.170
small molecule metabolic process GO:0044281 305 0.170
organic substance catabolic process GO:1901575 308 0.169
negative regulation of programmed cell death GO:0043069 72 0.169
Human Mouse
mrna metabolic process GO:0016071 124 0.163
circulatory system process GO:0003013 37 0.163
positive regulation of synapse assembly GO:0051965 29 0.163
negative regulation of erbb signaling pathway GO:1901185 29 0.161
negative regulation of developmental process GO:0051093 201 0.160
macromolecular complex assembly GO:0065003 256 0.160
stem cell development GO:0048864 79 0.160
positive regulation of protein metabolic process GO:0051247 128 0.158
Mouse
negative regulation of cellular metabolic process GO:0031324 382 0.157
Human Mouse
regulation of protein kinase activity GO:0045859 51 0.154
Mouse
renal tubule development GO:0061326 64 0.154
transcription from rna polymerase ii promoter GO:0006366 368 0.153
Mouse
columnar cuboidal epithelial cell differentiation GO:0002065 256 0.153
Zebrafish
mapk cascade GO:0000165 107 0.152
Human Mouse
hindbrain development GO:0030902 2 0.150
response to external biotic stimulus GO:0043207 293 0.148
transmembrane receptor protein serine threonine kinase signaling pathway GO:0007178 65 0.148
Human Mouse
digestive system development GO:0055123 149 0.147
single organism carbohydrate metabolic process GO:0044723 72 0.147
head development GO:0060322 135 0.142
nucleobase containing compound catabolic process GO:0034655 165 0.142
regulation of cellular component biogenesis GO:0044087 201 0.141
small gtpase mediated signal transduction GO:0007264 88 0.141
organic acid metabolic process GO:0006082 103 0.138
response to endogenous stimulus GO:0009719 119 0.137
Human Mouse
establishment of protein localization to organelle GO:0072594 62 0.137
fibroblast growth factor receptor signaling pathway GO:0008543 10 0.134
protein transport GO:0015031 155 0.134
positive regulation of cell proliferation GO:0008284 47 0.134
Mouse
negative regulation of protein phosphorylation GO:0001933 17 0.133
Mouse
cell cycle phase transition GO:0044770 140 0.132
regulation of organ morphogenesis GO:2000027 78 0.131
cell growth GO:0016049 108 0.130
regulation of small gtpase mediated signal transduction GO:0051056 93 0.130
oxoacid metabolic process GO:0043436 103 0.129
ectodermal placode morphogenesis GO:0071697 4 0.129
negative regulation of rna metabolic process GO:0051253 251 0.127
Human Mouse
negative regulation of rna biosynthetic process GO:1902679 240 0.127
Human Mouse
response to oxidative stress GO:0006979 86 0.126
cellular response to dna damage stimulus GO:0006974 223 0.125
Human Mouse
muscle cell differentiation GO:0042692 103 0.124
blood circulation GO:0008015 26 0.124
mrna catabolic process GO:0006402 33 0.123
aromatic compound catabolic process GO:0019439 166 0.122
organ formation GO:0048645 39 0.122
establishment of localization in cell GO:0051649 402 0.121
negative regulation of nitrogen compound metabolic process GO:0051172 265 0.120
Human Mouse
homeostatic process GO:0042592 199 0.118
cellular macromolecule localization GO:0070727 220 0.118
asymmetric neuroblast division GO:0055059 33 0.117
positive regulation of transcription from rna polymerase ii promoter GO:0045944 204 0.116
Mouse
positive regulation of nucleobase containing compound metabolic process GO:0045935 332 0.114
Human Mouse
negative regulation of biosynthetic process GO:0009890 277 0.113
Human Mouse
modification dependent macromolecule catabolic process GO:0043632 79 0.113
tube development GO:0035295 244 0.112
regulation of ras protein signal transduction GO:0046578 93 0.110
imaginal disc pattern formation GO:0007447 91 0.110
positive regulation of cell communication GO:0010647 250 0.110
positive regulation of endopeptidase activity GO:0010950 26 0.109
respiratory system development GO:0060541 213 0.108
regulation of phosphate metabolic process GO:0019220 210 0.107
Human Mouse
positive regulation of cellular protein metabolic process GO:0032270 118 0.107
Mouse
cell division GO:0051301 248 0.106
regulation of neural precursor cell proliferation GO:2000177 35 0.106
positive regulation of lipid catabolic process GO:0050996 1 0.105
spermatogenesis GO:0007283 200 0.105
response to extracellular stimulus GO:0009991 116 0.103
exocrine system development GO:0035272 162 0.103
organonitrogen compound metabolic process GO:1901564 318 0.103
neuron projection guidance GO:0097485 241 0.103
nephron morphogenesis GO:0072028 3 0.102
regulation of cellular component movement GO:0051270 42 0.100
hemopoiesis GO:0030097 46 0.100
regulation of apoptotic process GO:0042981 130 0.099
Human Mouse
photoreceptor cell development GO:0042461 96 0.099
regulation of neuron differentiation GO:0045664 103 0.098
dna metabolic process GO:0006259 227 0.097
response to nutrient levels GO:0031667 114 0.096
notch signaling pathway GO:0007219 120 0.096
humoral immune response GO:0006959 117 0.095
positive regulation of synaptic growth at neuromuscular junction GO:0045887 26 0.095
mitotic cell cycle phase transition GO:0044772 138 0.095
translation GO:0006412 69 0.094
negative regulation of phosphorus metabolic process GO:0010563 45 0.094
Mouse
sperm individualization GO:0007291 48 0.092
carbohydrate biosynthetic process GO:0016051 17 0.092
neuromuscular junction development GO:0007528 149 0.091
negative regulation of cell differentiation GO:0045596 143 0.091
regulation of growth GO:0040008 233 0.090
phagocytosis GO:0006909 215 0.087
regulation of locomotion GO:0040012 42 0.087
regulation of kinase activity GO:0043549 53 0.087
Mouse
aging GO:0007568 143 0.087
Worm
regulation of intracellular transport GO:0032386 64 0.086
regulation of cysteine type endopeptidase activity involved in apoptotic process GO:0043281 25 0.084
oocyte axis specification GO:0007309 108 0.084
negative regulation of protein metabolic process GO:0051248 85 0.084
Mouse
spermatid development GO:0007286 98 0.082
regulation of cellular amino acid metabolic process GO:0006521 0 0.082
morphogenesis of embryonic epithelium GO:0016331 94 0.082
protein modification by small protein conjugation or removal GO:0070647 106 0.082
regulation of cell cycle phase transition GO:1901987 130 0.081
carbohydrate derivative metabolic process GO:1901135 217 0.081
response to drug GO:0042493 17 0.081
dorsal closure GO:0007391 79 0.080
dendrite morphogenesis GO:0048813 199 0.080
gland development GO:0048732 191 0.080
response to bacterium GO:0009617 198 0.079
oocyte construction GO:0007308 112 0.078
formation of anatomical boundary GO:0048859 37 0.078
positive regulation of intracellular signal transduction GO:1902533 116 0.078
negative regulation of cellular protein metabolic process GO:0032269 85 0.078
Mouse
autophagy GO:0006914 108 0.077
cellular response to organonitrogen compound GO:0071417 36 0.077
regulation of synapse assembly GO:0051963 94 0.076
programmed cell death GO:0012501 257 0.076
axon guidance GO:0007411 233 0.076
negative regulation of cell cycle GO:0045786 116 0.075
proteolysis GO:0006508 192 0.075
positive regulation of signaling GO:0023056 243 0.075
maintenance of gastrointestinal epithelium GO:0030277 3 0.074
posttranscriptional gene silencing by rna GO:0035194 45 0.074
male gamete generation GO:0048232 201 0.074
embryo development ending in birth or egg hatching GO:0009792 152 0.073
regulation of cysteine type endopeptidase activity GO:2000116 27 0.073
dna repair GO:0006281 54 0.073
cell cell signaling involved in cell fate commitment GO:0045168 210 0.072
Mouse
segmentation GO:0035282 207 0.072
cellular response to endogenous stimulus GO:0071495 80 0.072
Human Mouse
cellular response to organic substance GO:0071310 132 0.072
Human Mouse
cellular nitrogen compound catabolic process GO:0044270 165 0.071
cell fate specification GO:0001708 71 0.071
regulation of neuroblast proliferation GO:1902692 34 0.071
nephron development GO:0072006 3 0.071
negative regulation of small gtpase mediated signal transduction GO:0051058 13 0.070
canonical wnt signaling pathway GO:0060070 21 0.070
rho protein signal transduction GO:0007266 14 0.070
regulation of protein phosphorylation GO:0001932 64 0.070
Mouse
positive regulation of locomotion GO:0040017 8 0.069
regulation of endopeptidase activity GO:0052548 36 0.069
regulation of catalytic activity GO:0050790 185 0.069
Mouse
positive regulation of phosphorylation GO:0042327 87 0.069
Human Mouse
response to glucose GO:0009749 2 0.068
epithelial cell development GO:0002064 274 0.068
stem cell maintenance GO:0019827 67 0.068
protein catabolic process GO:0030163 101 0.067
apoptotic signaling pathway GO:0097190 27 0.067
Human Mouse
cellular protein localization GO:0034613 160 0.067
semaphorin plexin signaling pathway GO:0071526 4 0.067
detection of external stimulus GO:0009581 66 0.067
regulation of intracellular protein transport GO:0033157 46 0.066
sensory perception GO:0007600 196 0.066
embryonic organ development GO:0048568 50 0.066
Mouse
embryonic pattern specification GO:0009880 174 0.066
positive regulation of cysteine type endopeptidase activity involved in apoptotic process GO:0043280 23 0.066
positive regulation of cellular amine metabolic process GO:0033240 0 0.066
regulation of phosphorus metabolic process GO:0051174 210 0.065
Human Mouse
regulation of cellular response to stress GO:0080135 89 0.065
Human Mouse
positive regulation of biosynthetic process GO:0009891 316 0.065
Human Mouse
negative regulation of cellular response to growth factor stimulus GO:0090288 6 0.064
regulation of cell cycle process GO:0010564 181 0.064
central nervous system development GO:0007417 201 0.064
intrinsic apoptotic signaling pathway GO:0097193 16 0.063
Mouse
stem cell differentiation GO:0048863 117 0.063
muscle system process GO:0003012 21 0.062
positive regulation of cell differentiation GO:0045597 64 0.062
regulation of cell development GO:0060284 215 0.062
endocytosis GO:0006897 310 0.062
neuroblast division GO:0055057 35 0.062
cellular response to carbohydrate stimulus GO:0071322 4 0.062
regulation of cellular amine metabolic process GO:0033238 3 0.061
apposition of dorsal and ventral imaginal disc derived wing surfaces GO:0007475 15 0.060
gliogenesis GO:0042063 80 0.059
response to wounding GO:0009611 94 0.059
negative regulation of transferase activity GO:0051348 18 0.059
Mouse
positive regulation of cellular amino acid metabolic process GO:0045764 0 0.059
telencephalon development GO:0021537 2 0.059
positive regulation of catalytic activity GO:0043085 118 0.058
response to hexose GO:0009746 3 0.057
regulation of protein transport GO:0051223 57 0.057
cellular response to fibroblast growth factor stimulus GO:0044344 10 0.057
dorsal ventral axis specification GO:0009950 66 0.057
transforming growth factor beta receptor signaling pathway GO:0007179 16 0.056
Human Mouse
cell activation GO:0001775 9 0.056
regulation of cytoplasmic transport GO:1903649 47 0.056
establishment of planar polarity GO:0001736 87 0.055
ribose phosphate metabolic process GO:0019693 145 0.055
leg disc morphogenesis GO:0007478 80 0.055
positive regulation of response to external stimulus GO:0032103 44 0.054
positive regulation of protein modification process GO:0031401 58 0.054
Mouse
chemotaxis GO:0006935 249 0.054
gonad development GO:0008406 50 0.054
rhythmic process GO:0048511 106 0.053
negative regulation of kinase activity GO:0033673 16 0.053
Mouse
positive regulation of cell development GO:0010720 61 0.053
protein targeting to nucleus GO:0044744 51 0.052
axon choice point recognition GO:0016198 26 0.052
rna processing GO:0006396 147 0.052
immune effector process GO:0002252 98 0.051
gravitaxis GO:0042332 26 0.051
positive regulation of signal transduction GO:0009967 223 0.051
peptidyl amino acid modification GO:0018193 105 0.051
Mouse
response to oxygen containing compound GO:1901700 200 0.051
secondary metabolic process GO:0019748 75 0.050
multi organism behavior GO:0051705 175 0.050
positive regulation of cellular component biogenesis GO:0044089 80 0.049
renal filtration GO:0097205 7 0.049
negative regulation of cell death GO:0060548 81 0.049
Human Mouse
renal system development GO:0072001 72 0.049
protein targeting GO:0006605 64 0.048
cell junction organization GO:0034330 57 0.048
neuronal stem cell division GO:0036445 35 0.048
imaginal disc derived leg morphogenesis GO:0007480 80 0.048
antimicrobial humoral response GO:0019730 99 0.048
regulation of photoreceptor cell differentiation GO:0046532 34 0.048
response to heat GO:0009408 63 0.048
regulation of multicellular organismal development GO:2000026 414 0.048
Human Zebrafish
regulation of stem cell proliferation GO:0072091 40 0.048
brain development GO:0007420 120 0.047
amine metabolic process GO:0009308 12 0.047
positive regulation of cellular catabolic process GO:0031331 95 0.047
oocyte differentiation GO:0009994 145 0.047
anterior posterior pattern specification GO:0009952 136 0.047
Mouse
negative regulation of immune system process GO:0002683 50 0.047
regulation of catabolic process GO:0009894 170 0.046
multicellular organismal aging GO:0010259 140 0.046
Worm
negative regulation of phosphate metabolic process GO:0045936 45 0.045
Mouse
erk1 and erk2 cascade GO:0070371 39 0.045
neuroblast differentiation GO:0014016 29 0.045
nuclear import GO:0051170 51 0.045
kidney development GO:0001822 3 0.044
negative regulation of nervous system development GO:0051961 92 0.043
regulation of mitotic cell cycle phase transition GO:1901990 130 0.043
regulation of production of molecular mediator of immune response GO:0002700 44 0.043
imaginal disc derived wing vein specification GO:0007474 48 0.042
regulation of anatomical structure morphogenesis GO:0022603 242 0.042
Human
reproductive structure development GO:0048608 74 0.042
contractile actin filament bundle assembly GO:0030038 1 0.042
rna interference GO:0016246 27 0.042
modification dependent protein catabolic process GO:0019941 78 0.042
motor neuron axon guidance GO:0008045 58 0.042
meiotic cell cycle GO:0051321 171 0.042
positive regulation of protein phosphorylation GO:0001934 34 0.041
Mouse
regulation of cell migration GO:0030334 22 0.041
establishment of protein localization GO:0045184 163 0.041
gene silencing GO:0016458 138 0.041
positive regulation of peptidase activity GO:0010952 29 0.040
regulation of cellular ketone metabolic process GO:0010565 3 0.040
purine nucleoside triphosphate catabolic process GO:0009146 108 0.040
regulation of multi organism process GO:0043900 131 0.040
single organism behavior GO:0044708 391 0.040
Mouse
female gonad development GO:0008585 12 0.040
peripheral nervous system development GO:0007422 52 0.040
establishment of spindle orientation GO:0051294 18 0.040
imaginal disc derived wing hair site selection GO:0035320 4 0.039
intrinsic apoptotic signaling pathway in response to dna damage GO:0008630 11 0.039
Mouse
regulation of response to biotic stimulus GO:0002831 63 0.039
renal tubule morphogenesis GO:0061333 44 0.039
nephron epithelium development GO:0072009 3 0.039
spinal cord development GO:0021510 1 0.039
negative regulation of multicellular organismal process GO:0051241 142 0.038
rna splicing GO:0008380 83 0.038
regulation of transferase activity GO:0051338 58 0.038
Mouse
lipopolysaccharide mediated signaling pathway GO:0031663 1 0.038
protein localization to organelle GO:0033365 82 0.037
regulation of heart contraction GO:0008016 21 0.037
actin filament bundle organization GO:0061572 28 0.037
dendrite development GO:0016358 204 0.036
regulation of embryonic development GO:0045995 68 0.036
response to fibroblast growth factor GO:0071774 10 0.035
endoderm formation GO:0001706 3 0.035
positive regulation of r7 cell differentiation GO:0045678 7 0.035
sex differentiation GO:0007548 81 0.035
smad protein import into nucleus GO:0007184 11 0.035
embryonic organ morphogenesis GO:0048562 5 0.035
Mouse
synaptic transmission GO:0007268 288 0.035
regulation of cellular catabolic process GO:0031329 157 0.035
body morphogenesis GO:0010171 2 0.034
stress fiber assembly GO:0043149 6 0.034
glial cell differentiation GO:0010001 35 0.034
stem cell proliferation GO:0072089 88 0.034
actin cytoskeleton reorganization GO:0031532 22 0.034
wing disc dorsal ventral pattern formation GO:0048190 47 0.033
epithelial tube morphogenesis GO:0060562 88 0.033
regulation of actin cytoskeleton organization GO:0032956 42 0.033
regulation of mrna processing GO:0050684 71 0.033
protein modification by small protein conjugation GO:0032446 79 0.033
cellular amino acid metabolic process GO:0006520 61 0.033
positive regulation of cell adhesion GO:0045785 10 0.033
negative regulation of ras protein signal transduction GO:0046580 13 0.032
regulation of translation GO:0006417 56 0.032
leg disc development GO:0035218 92 0.032
nephron tubule development GO:0072080 3 0.032
cortical actin cytoskeleton organization GO:0030866 24 0.032
regulation of blood circulation GO:1903522 21 0.032
cellular carbohydrate metabolic process GO:0044262 22 0.032
positive regulation of wnt signaling pathway GO:0030177 25 0.032
chromatin remodeling GO:0006338 72 0.032
positive regulation of cell cycle GO:0045787 43 0.031
organic cyclic compound catabolic process GO:1901361 168 0.031
kidney morphogenesis GO:0060993 3 0.031
positive regulation of protein transport GO:0051222 37 0.031
r7 cell fate commitment GO:0007465 12 0.031
ubiquitin dependent protein catabolic process GO:0006511 78 0.031
gene silencing by rna GO:0031047 57 0.030
cellular response to extracellular stimulus GO:0031668 64 0.030
protein complex assembly GO:0006461 200 0.030
cellular chemical homeostasis GO:0055082 40 0.030
regulation of epithelial cell differentiation GO:0030856 4 0.030
Zebrafish
response to ketone GO:1901654 34 0.030
wound healing GO:0042060 75 0.030
imaginal disc derived wing hair outgrowth GO:0035318 1 0.030
dorsal ventral axon guidance GO:0033563 2 0.030
ventral cord development GO:0007419 16 0.029
establishment of ommatidial planar polarity GO:0042067 49 0.029
regulation of cell cell adhesion GO:0022407 21 0.029
negative regulation of apoptotic process GO:0043066 63 0.029
Human Mouse
nephron epithelium morphogenesis GO:0072088 3 0.028
stem cell fate commitment GO:0048865 25 0.028
stem cell fate specification GO:0048866 2 0.028
hair cell differentiation GO:0035315 47 0.028
nephron tubule morphogenesis GO:0072078 3 0.028
heart process GO:0003015 37 0.027
cardiac cell fate commitment GO:0060911 17 0.027
response to hormone GO:0009725 45 0.027
immune response regulating signaling pathway GO:0002764 2 0.027
response to nitrogen compound GO:1901698 90 0.027
cell cell junction organization GO:0045216 55 0.027
neuroblast proliferation GO:0007405 74 0.027
defense response to other organism GO:0098542 225 0.027
production of molecular mediator of immune response GO:0002440 46 0.026
regulation of protein catabolic process GO:0042176 55 0.026
embryonic hemopoiesis GO:0035162 26 0.026
cellular response to external stimulus GO:0071496 66 0.026

hipk disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in fly and predicted with the fly functional network.

Disease DO term ID Size Probability Func Analog Org