Drosophila melanogaster

26 known processes

Xpac (Dmel_CG6358)

Xeroderma pigmentosum group A-like

(Aliases: DhXPA,Dxpa,dxpa,Dmel\CG6358,DmXPA,Xpa,dmXPA,EG:EG0007.8,DhR14,XPA_DROME,XPAC,CG6358)

Xpac biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
imaginal disc derived appendage morphogenesis GO:0035114 395 0.357
wing disc morphogenesis GO:0007472 344 0.322
post embryonic appendage morphogenesis GO:0035120 385 0.223
imaginal disc derived appendage development GO:0048737 399 0.206
appendage morphogenesis GO:0035107 397 0.199
appendage development GO:0048736 401 0.149
imaginal disc derived wing morphogenesis GO:0007476 337 0.133
positive regulation of nucleobase containing compound metabolic process GO:0045935 332 0.109
positive regulation of gene expression GO:0010628 290 0.094
negative regulation of gene expression GO:0010629 387 0.093
olfactory behavior GO:0042048 97 0.081
immune system process GO:0002376 347 0.069
negative regulation of cellular metabolic process GO:0031324 382 0.061
positive regulation of nitrogen compound metabolic process GO:0051173 354 0.061
gene silencing GO:0016458 138 0.058
single organism behavior GO:0044708 391 0.057
negative regulation of rna metabolic process GO:0051253 251 0.057
positive regulation of cellular biosynthetic process GO:0031328 316 0.056
positive regulation of transcription dna templated GO:0045893 266 0.056
protein modification process GO:0036211 438 0.053
actin filament based process GO:0030029 220 0.052
positive regulation of macromolecule biosynthetic process GO:0010557 283 0.050
nucleobase containing compound catabolic process GO:0034655 165 0.050
cellular protein modification process GO:0006464 438 0.047
organic substance catabolic process GO:1901575 308 0.047
meiotic nuclear division GO:0007126 151 0.045
dna metabolic process GO:0006259 227 0.044
regulation of response to stress GO:0080134 200 0.042
defense response GO:0006952 300 0.042
vesicle mediated transport GO:0016192 381 0.041
negative regulation of cellular biosynthetic process GO:0031327 277 0.041
aging GO:0007568 143 0.040
negative regulation of nitrogen compound metabolic process GO:0051172 265 0.039
chemosensory behavior GO:0007635 106 0.039
cellular macromolecule catabolic process GO:0044265 136 0.038
response to bacterium GO:0009617 198 0.038
actin cytoskeleton organization GO:0030036 206 0.037
endocytosis GO:0006897 310 0.036
protein modification by small protein conjugation or removal GO:0070647 106 0.036
response to extracellular stimulus GO:0009991 116 0.035
negative regulation of transcription dna templated GO:0045892 237 0.034
body morphogenesis GO:0010171 2 0.034
heterochromatin organization GO:0070828 25 0.034
catabolic process GO:0009056 409 0.033
chromatin silencing GO:0006342 76 0.033
cellular nitrogen compound catabolic process GO:0044270 165 0.032
cellular response to extracellular stimulus GO:0031668 64 0.031
regulation of molecular function GO:0065009 217 0.031
transcription from rna polymerase ii promoter GO:0006366 368 0.030
growth GO:0040007 359 0.030
response to temperature stimulus GO:0009266 106 0.030
negative regulation of biosynthetic process GO:0009890 277 0.030
ion transmembrane transport GO:0034220 122 0.030
multicellular organismal aging GO:0010259 140 0.030
positive regulation of biosynthetic process GO:0009891 316 0.030
aromatic compound catabolic process GO:0019439 166 0.029
purine ribonucleotide metabolic process GO:0009150 145 0.029
heterocycle catabolic process GO:0046700 166 0.029
negative regulation of nucleic acid templated transcription GO:1903507 240 0.029
organelle fission GO:0048285 340 0.028
positive regulation of nucleic acid templated transcription GO:1903508 266 0.027
eye development GO:0001654 323 0.027
macromolecule catabolic process GO:0009057 161 0.027
compound eye development GO:0048749 307 0.027
oocyte construction GO:0007308 112 0.027
meiotic cell cycle GO:0051321 171 0.027
regulation of transcription from rna polymerase ii promoter GO:0006357 378 0.027
organic cyclic compound catabolic process GO:1901361 168 0.026
response to nutrient levels GO:0031667 114 0.026
negative regulation of response to stimulus GO:0048585 258 0.026
positive regulation of rna metabolic process GO:0051254 271 0.026
positive regulation of transcription from rna polymerase ii promoter GO:0045944 204 0.025
phosphorylation GO:0016310 294 0.025
regulation of organelle organization GO:0033043 196 0.025
chromatin organization GO:0006325 207 0.025
cell division GO:0051301 248 0.025
regulation of catalytic activity GO:0050790 185 0.024
regulation of cell cycle process GO:0010564 181 0.024
negative regulation of cellular macromolecule biosynthetic process GO:2000113 267 0.024
regulation of mitotic cell cycle GO:0007346 190 0.024
phagocytosis GO:0006909 215 0.024
protein localization GO:0008104 284 0.023
negative regulation of nucleobase containing compound metabolic process GO:0045934 261 0.023
nucleoside triphosphate metabolic process GO:0009141 120 0.022
cellular macromolecule localization GO:0070727 220 0.022
enzyme linked receptor protein signaling pathway GO:0007167 179 0.022
single organism cellular localization GO:1902580 180 0.022
regionalization GO:0003002 416 0.022
protein modification by small protein conjugation GO:0032446 79 0.021
embryonic pattern specification GO:0009880 174 0.021
regulation of cell cycle phase transition GO:1901987 130 0.020
regulation of gene expression epigenetic GO:0040029 128 0.020
apoptotic process GO:0006915 159 0.020
eye morphogenesis GO:0048592 260 0.020
cell growth GO:0016049 108 0.020
rna interference GO:0016246 27 0.020
establishment of localization in cell GO:0051649 402 0.020
single organism catabolic process GO:0044712 228 0.020
purine nucleoside triphosphate catabolic process GO:0009146 108 0.020
death GO:0016265 284 0.020
organonitrogen compound metabolic process GO:1901564 318 0.019
positive regulation of rna biosynthetic process GO:1902680 266 0.019
programmed cell death GO:0012501 257 0.019
purine containing compound metabolic process GO:0072521 155 0.019
purine ribonucleoside triphosphate catabolic process GO:0009207 108 0.019
response to heat GO:0009408 63 0.019
amine metabolic process GO:0009308 12 0.019
cellular catabolic process GO:0044248 372 0.019
cell proliferation GO:0008283 299 0.019
negative regulation of macromolecule biosynthetic process GO:0010558 270 0.018
mrna metabolic process GO:0016071 124 0.018
protein phosphorylation GO:0006468 169 0.018
modification dependent protein catabolic process GO:0019941 78 0.018
developmental maturation GO:0021700 172 0.018
purine nucleotide metabolic process GO:0006163 146 0.018
sensory organ morphogenesis GO:0090596 260 0.018
response to other organism GO:0051707 293 0.018
response to abiotic stimulus GO:0009628 341 0.018
ribonucleoside catabolic process GO:0042454 112 0.018
oxoacid metabolic process GO:0043436 103 0.018
purine ribonucleoside metabolic process GO:0046128 127 0.018
regulation of multicellular organismal development GO:2000026 414 0.018
ribonucleoside metabolic process GO:0009119 127 0.018
regulation of cell cycle GO:0051726 291 0.018
negative regulation of immune system process GO:0002683 50 0.017
response to biotic stimulus GO:0009607 294 0.017
ubiquitin dependent protein catabolic process GO:0006511 78 0.017
intracellular signal transduction GO:0035556 300 0.017
response to oxygen containing compound GO:1901700 200 0.017
camera type eye development GO:0043010 4 0.017
taxis GO:0042330 304 0.017
neuron projection guidance GO:0097485 241 0.017
guanosine containing compound catabolic process GO:1901069 74 0.016
nucleobase containing small molecule metabolic process GO:0055086 174 0.016
proteolysis GO:0006508 192 0.016
developmental growth GO:0048589 280 0.016
ribose phosphate metabolic process GO:0019693 145 0.016
axonogenesis GO:0007409 290 0.016
synapse assembly GO:0007416 143 0.016
nucleoside metabolic process GO:0009116 127 0.016
dna repair GO:0006281 54 0.016
regulation of cellular catabolic process GO:0031329 157 0.016
carboxylic acid metabolic process GO:0019752 92 0.016
regulation of cellular ketone metabolic process GO:0010565 3 0.016
cellular response to dna damage stimulus GO:0006974 223 0.016
cell aging GO:0007569 2 0.016
cellular amino acid metabolic process GO:0006520 61 0.016
axis specification GO:0009798 167 0.016
positive regulation of macromolecule metabolic process GO:0010604 405 0.015
chemotaxis GO:0006935 249 0.015
cellular response to chemical stimulus GO:0070887 199 0.015
negative regulation of rna biosynthetic process GO:1902679 240 0.015
cell maturation GO:0048469 144 0.015
regulation of phosphate metabolic process GO:0019220 210 0.015
regulation of chromatin silencing GO:0031935 36 0.015
peptidyl amino acid modification GO:0018193 105 0.015
nuclear division GO:0000280 332 0.015
guanosine containing compound metabolic process GO:1901068 74 0.015
purine nucleoside catabolic process GO:0006152 112 0.015
small molecule metabolic process GO:0044281 305 0.015
compound eye photoreceptor cell differentiation GO:0001751 140 0.015
neurological system process GO:0050877 358 0.015
tube development GO:0035295 244 0.015
purine containing compound catabolic process GO:0072523 112 0.014
anatomical structure homeostasis GO:0060249 97 0.014
detection of stimulus GO:0051606 156 0.014
leg disc morphogenesis GO:0007478 80 0.014
nucleoside phosphate catabolic process GO:1901292 110 0.014
ras protein signal transduction GO:0007265 88 0.014
regulation of programmed cell death GO:0043067 152 0.014
organic acid metabolic process GO:0006082 103 0.014
cell death GO:0008219 279 0.014
spindle organization GO:0007051 253 0.014
positive regulation of molecular function GO:0044093 136 0.014
androgen metabolic process GO:0008209 1 0.014
ribonucleotide metabolic process GO:0009259 145 0.014
segmentation GO:0035282 207 0.014
negative regulation of cell differentiation GO:0045596 143 0.014
oocyte differentiation GO:0009994 145 0.014
compound eye morphogenesis GO:0001745 249 0.014
regulation of transport GO:0051049 181 0.014
carbohydrate derivative metabolic process GO:1901135 217 0.014
developmental pigmentation GO:0048066 68 0.014
negative regulation of signaling GO:0023057 219 0.013
regulation of cell death GO:0010941 173 0.013
nucleoside phosphate metabolic process GO:0006753 162 0.013
negative regulation of cell cycle process GO:0010948 109 0.013
macromolecular complex assembly GO:0065003 256 0.013
meiotic cell cycle process GO:1903046 132 0.013
determination of adult lifespan GO:0008340 137 0.013
oocyte development GO:0048599 124 0.013
regulation of mrna splicing via spliceosome GO:0048024 64 0.013
response to external biotic stimulus GO:0043207 293 0.013
negative regulation of cell death GO:0060548 81 0.013
glycosyl compound catabolic process GO:1901658 112 0.013
negative regulation of protein metabolic process GO:0051248 85 0.013
dendrite development GO:0016358 204 0.013
blastoderm segmentation GO:0007350 159 0.013
regulation of i kappab kinase nf kappab signaling GO:0043122 2 0.013
oocyte axis specification GO:0007309 108 0.013
carbohydrate derivative catabolic process GO:1901136 118 0.012
regulation of cell division GO:0051302 72 0.012
photoreceptor cell differentiation GO:0046530 170 0.012
negative regulation of signal transduction GO:0009968 206 0.012
regulation of immune system process GO:0002682 176 0.012
rna catabolic process GO:0006401 37 0.012
purine nucleoside metabolic process GO:0042278 127 0.012
positive regulation of response to stimulus GO:0048584 323 0.012
eye photoreceptor cell differentiation GO:0001754 145 0.012
spermatogenesis GO:0007283 200 0.012
regulation of multi organism process GO:0043900 131 0.012
nucleotide catabolic process GO:0009166 109 0.012
protein complex biogenesis GO:0070271 201 0.012
nucleoside catabolic process GO:0009164 112 0.012
regulation of phosphorus metabolic process GO:0051174 210 0.012
regulation of catabolic process GO:0009894 170 0.012
camera type eye morphogenesis GO:0048593 2 0.012
regulation of hydrolase activity GO:0051336 97 0.012
meiosis i GO:0007127 59 0.012
regulation of cellular amine metabolic process GO:0033238 3 0.012
tissue morphogenesis GO:0048729 297 0.012
regulation of response to external stimulus GO:0032101 115 0.012
single organism membrane organization GO:0044802 93 0.011
regulation of apoptotic process GO:0042981 130 0.011
rna splicing GO:0008380 83 0.011
organophosphate biosynthetic process GO:0090407 46 0.011
regulation of nuclear division GO:0051783 58 0.011
organonitrogen compound biosynthetic process GO:1901566 117 0.011
gtp catabolic process GO:0006184 72 0.011
embryo development ending in birth or egg hatching GO:0009792 152 0.011
regulation of synapse structure and activity GO:0050803 128 0.011
protein localization to organelle GO:0033365 82 0.011
negative regulation of gene expression epigenetic GO:0045814 77 0.011
organonitrogen compound catabolic process GO:1901565 128 0.011
defense response to bacterium GO:0042742 178 0.011
protein ubiquitination GO:0016567 70 0.011
nucleoside triphosphate catabolic process GO:0009143 108 0.011
negative regulation of cellular protein metabolic process GO:0032269 85 0.011
jak stat cascade GO:0007259 49 0.011
purine ribonucleotide catabolic process GO:0009154 109 0.011
epithelial cell development GO:0002064 274 0.011
mitotic spindle organization GO:0007052 220 0.011
mrna catabolic process GO:0006402 33 0.011
purine nucleoside triphosphate metabolic process GO:0009144 119 0.011
cellular response to external stimulus GO:0071496 66 0.011
gland development GO:0048732 191 0.011
purine ribonucleoside triphosphate metabolic process GO:0009205 119 0.011
epidermal growth factor receptor signaling pathway GO:0007173 58 0.011
ribonucleotide catabolic process GO:0009261 109 0.011
synaptic growth at neuromuscular junction GO:0051124 119 0.011
ribonucleoside triphosphate catabolic process GO:0009203 108 0.011
cellularization GO:0007349 90 0.011
transmembrane receptor protein serine threonine kinase signaling pathway GO:0007178 65 0.010
response to endogenous stimulus GO:0009719 119 0.010
dendrite morphogenesis GO:0048813 199 0.010
gtp metabolic process GO:0046039 72 0.010
regulation of defense response GO:0031347 102 0.010
dna recombination GO:0006310 32 0.010
rna localization GO:0006403 115 0.010
regulation of cellular response to stress GO:0080135 89 0.010
cation transport GO:0006812 110 0.010
cellular response to heat GO:0034605 24 0.010
response to starvation GO:0042594 97 0.010

Xpac disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in fly and predicted with the fly functional network.

Disease DO term ID Size Probability Func Analog Org
disease of anatomical entity DOID:7 0 0.048
nervous system disease DOID:863 0 0.022
disease of cellular proliferation DOID:14566 0 0.011
cancer DOID:162 0 0.011
organ system cancer DOID:0050686 0 0.011