Drosophila melanogaster

0 known processes

Pgd (Dmel_CG3724)

Phosphogluconate dehydrogenase

(Aliases: EG:87B1.4,pgd,6Pgdh,l(1)Pgd-A,l(1)A7,l35,PGD,6PGDH,l(1)Pgd,6-pgd,6Pgd,A7,l(1)2Dc,l(1)N3[90],l(1)2De,Dmel\CG3724,6-Pgd,Pdg,N1,CG3724,6-PGD,6pgdh,l(1)G0385,l(1)N1,6PGD)

Pgd biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
pyridine containing compound metabolic process GO:0072524 3 0.547
catabolic process GO:0009056 409 0.464
oxidoreduction coenzyme metabolic process GO:0006733 2 0.458
small molecule metabolic process GO:0044281 305 0.439
pigment metabolic process involved in pigmentation GO:0043474 33 0.389
organonitrogen compound metabolic process GO:1901564 318 0.350
single organism biosynthetic process GO:0044711 206 0.296
Mouse
pigment metabolic process GO:0042440 84 0.288
pigment biosynthetic process GO:0046148 36 0.280
organic substance catabolic process GO:1901575 308 0.249
response to organic substance GO:0010033 284 0.244
pyridine nucleotide metabolic process GO:0019362 2 0.244
oxidation reduction process GO:0055114 123 0.205
Mouse
eye pigment metabolic process GO:0042441 33 0.199
carboxylic acid metabolic process GO:0019752 92 0.167
lateral inhibition GO:0046331 206 0.163
response to oxygen containing compound GO:1901700 200 0.162
organonitrogen compound biosynthetic process GO:1901566 117 0.157
nucleobase containing small molecule metabolic process GO:0055086 174 0.156
cell death GO:0008219 279 0.149
carbohydrate catabolic process GO:0016052 7 0.147
pigment metabolic process involved in developmental pigmentation GO:0043324 33 0.132
ion transport GO:0006811 145 0.132
single organism carbohydrate metabolic process GO:0044723 72 0.131
Mouse
single organism behavior GO:0044708 391 0.128
response to alcohol GO:0097305 95 0.125
response to ethanol GO:0045471 59 0.122
apoptotic process GO:0006915 159 0.122
single organism catabolic process GO:0044712 228 0.119
organophosphate metabolic process GO:0019637 195 0.118
monocarboxylic acid metabolic process GO:0032787 29 0.116
cell type specific apoptotic process GO:0097285 38 0.100
atp biosynthetic process GO:0006754 2 0.097
nicotinamide nucleotide metabolic process GO:0046496 2 0.086
eye pigmentation GO:0048069 43 0.086
adult behavior GO:0030534 137 0.086
endocytosis GO:0006897 310 0.086
nucleotide metabolic process GO:0009117 161 0.084
death GO:0016265 284 0.083
nucleoside phosphate metabolic process GO:0006753 162 0.080
pigmentation GO:0043473 75 0.079
cell cell signaling involved in cell fate commitment GO:0045168 210 0.079
carbohydrate derivative metabolic process GO:1901135 217 0.074
positive regulation of transport GO:0051050 92 0.073
response to nutrient levels GO:0031667 114 0.072
oxoacid metabolic process GO:0043436 103 0.070
polysaccharide biosynthetic process GO:0000271 7 0.070
organic substance transport GO:0071702 257 0.069
energy derivation by oxidation of organic compounds GO:0015980 32 0.068
programmed cell death GO:0012501 257 0.067
regulation of programmed cell death GO:0043067 152 0.066
response to organic cyclic compound GO:0014070 89 0.065
maintenance of location GO:0051235 73 0.064
regulation of localization GO:0032879 275 0.064
appendage development GO:0048736 401 0.063
regulation of cell death GO:0010941 173 0.060
cellular ketone metabolic process GO:0042180 24 0.059
eye pigment biosynthetic process GO:0006726 32 0.059
neurological system process GO:0050877 358 0.057
glutathione metabolic process GO:0006749 37 0.056
fatty acid metabolic process GO:0006631 20 0.055
associative learning GO:0008306 65 0.053
gastrulation involving germ band extension GO:0010004 36 0.053
carboxylic acid biosynthetic process GO:0046394 15 0.052
organelle assembly GO:0070925 198 0.050
learning or memory GO:0007611 141 0.049
homeostatic process GO:0042592 199 0.049
transmembrane transport GO:0055085 139 0.049
lipid modification GO:0030258 24 0.048
glutamate metabolic process GO:0006536 5 0.048
regulation of neuron death GO:1901214 26 0.047
cellular response to chemical stimulus GO:0070887 199 0.047
regulation of cellular ketone metabolic process GO:0010565 3 0.047
carbohydrate metabolic process GO:0005975 82 0.044
Mouse
response to radiation GO:0009314 155 0.043
tube morphogenesis GO:0035239 191 0.043
regulation of transport GO:0051049 181 0.042
organic acid metabolic process GO:0006082 103 0.041
ribonucleoside biosynthetic process GO:0042455 3 0.041
detection of stimulus GO:0051606 156 0.040
regulation of apoptotic process GO:0042981 130 0.040
phagocytosis GO:0006909 215 0.040
telencephalon development GO:0021537 2 0.039
central nervous system development GO:0007417 201 0.039
salivary gland morphogenesis GO:0007435 145 0.039
anion transport GO:0006820 41 0.038
synapse assembly GO:0007416 143 0.038
organophosphate biosynthetic process GO:0090407 46 0.038
cognition GO:0050890 141 0.037
small molecule biosynthetic process GO:0044283 37 0.037
cellular response to organic substance GO:0071310 132 0.037
monosaccharide metabolic process GO:0005996 9 0.037
Mouse
learning GO:0007612 75 0.036
ion transmembrane transport GO:0034220 122 0.036
sulfur compound metabolic process GO:0006790 59 0.036
lipid localization GO:0010876 54 0.035
body morphogenesis GO:0010171 2 0.035
regulation of cellular localization GO:0060341 136 0.035
cellular catabolic process GO:0044248 372 0.035
carbohydrate biosynthetic process GO:0016051 17 0.035
Mouse
cellular amine metabolic process GO:0044106 12 0.034
cellular biogenic amine catabolic process GO:0042402 1 0.034
response to monosaccharide GO:0034284 4 0.034
acylglycerol catabolic process GO:0046464 3 0.033
positive regulation of response to stimulus GO:0048584 323 0.033
intracellular transport GO:0046907 228 0.032
morphogenesis of follicular epithelium GO:0016333 36 0.032
salivary gland histolysis GO:0035070 88 0.032
carbohydrate derivative biosynthetic process GO:1901137 85 0.032
chemical homeostasis GO:0048878 92 0.032
purine nucleoside biosynthetic process GO:0042451 3 0.032
glycosyl compound metabolic process GO:1901657 127 0.031
single organism carbohydrate catabolic process GO:0044724 7 0.031
glycosyl compound biosynthetic process GO:1901659 3 0.031
regulation of anatomical structure size GO:0090066 163 0.030
negative regulation of nitrogen compound metabolic process GO:0051172 265 0.030
developmental growth GO:0048589 280 0.030
forebrain development GO:0030900 2 0.030
cellular component assembly involved in morphogenesis GO:0010927 151 0.030
response to abiotic stimulus GO:0009628 341 0.029
cellular lipid catabolic process GO:0044242 16 0.029
sulfur compound biosynthetic process GO:0044272 16 0.028
nucleoside metabolic process GO:0009116 127 0.028
mitotic spindle organization GO:0007052 220 0.028
regulation of sequestering of calcium ion GO:0051282 3 0.028
cellular lipid metabolic process GO:0044255 83 0.028
olfactory behavior GO:0042048 97 0.028
neuron death GO:0070997 27 0.028
cation homeostasis GO:0055080 51 0.028
cellular polysaccharide metabolic process GO:0044264 11 0.027
negative regulation of cell communication GO:0010648 223 0.027
hexose metabolic process GO:0019318 8 0.027
regulation of cellular amino acid metabolic process GO:0006521 0 0.027
wound healing GO:0042060 75 0.027
regulation of neuron apoptotic process GO:0043523 16 0.026
cellular amino acid metabolic process GO:0006520 61 0.026
monocarboxylic acid transport GO:0015718 3 0.025
purine containing compound metabolic process GO:0072521 155 0.025
establishment of localization in cell GO:0051649 402 0.025
positive regulation of signaling GO:0023056 243 0.025
striated muscle myosin thick filament assembly GO:0071688 3 0.024
establishment or maintenance of cell polarity GO:0007163 167 0.024
camera type eye development GO:0043010 4 0.024
single organism intracellular transport GO:1902582 207 0.023
nitrogen compound transport GO:0071705 85 0.023
response to extracellular stimulus GO:0009991 116 0.023
regulation of imaginal disc derived wing size GO:0044719 20 0.023
vitamin metabolic process GO:0006766 2 0.023
regulation of multi organism process GO:0043900 131 0.023
meiotic nuclear division GO:0007126 151 0.023
embryonic morphogenesis GO:0048598 206 0.023
imaginal disc derived appendage morphogenesis GO:0035114 395 0.022
response to light stimulus GO:0009416 124 0.022
spindle organization GO:0007051 253 0.022
cellular modified amino acid metabolic process GO:0006575 45 0.022
sterol homeostasis GO:0055092 4 0.022
response to glucose GO:0009749 2 0.022
negative regulation of biosynthetic process GO:0009890 277 0.022
gland development GO:0048732 191 0.022
negative regulation of cellular biosynthetic process GO:0031327 277 0.021
retina development in camera type eye GO:0060041 4 0.021
morphogenesis of an epithelium GO:0002009 276 0.021
meiotic cell cycle GO:0051321 171 0.021
cell aging GO:0007569 2 0.021
ion homeostasis GO:0050801 55 0.021
ocellus pigment metabolic process GO:0046158 19 0.021
negative regulation of cellular metabolic process GO:0031324 382 0.021
gland morphogenesis GO:0022612 145 0.021
anatomical structure homeostasis GO:0060249 97 0.021
post embryonic appendage morphogenesis GO:0035120 385 0.021
taxis GO:0042330 304 0.020
purine ribonucleoside monophosphate biosynthetic process GO:0009168 3 0.020
aromatic compound catabolic process GO:0019439 166 0.020
cellular response to oxygen containing compound GO:1901701 79 0.020
behavioral response to ethanol GO:0048149 49 0.020
lipid catabolic process GO:0016042 21 0.020
ribonucleoside metabolic process GO:0009119 127 0.020
kidney epithelium development GO:0072073 3 0.020
vesicle mediated transport GO:0016192 381 0.020
age dependent general metabolic decline GO:0007571 3 0.020
regulation of cell proliferation GO:0042127 163 0.020
negative regulation of response to stimulus GO:0048585 258 0.019
regulation of gene silencing GO:0060968 63 0.019
nephron epithelium development GO:0072009 3 0.019
cellular homeostasis GO:0019725 80 0.019
purine nucleotide metabolic process GO:0006163 146 0.019
negative regulation of sequestering of calcium ion GO:0051283 2 0.018
mesenchymal cell development GO:0014031 1 0.018
posttranscriptional regulation of gene expression GO:0010608 145 0.018
regulation of cell cycle GO:0051726 291 0.018
cholesterol homeostasis GO:0042632 3 0.018
organic acid transport GO:0015849 18 0.018
epithelial cell differentiation GO:0030855 322 0.018
purine nucleoside triphosphate metabolic process GO:0009144 119 0.018
regulation of gene expression epigenetic GO:0040029 128 0.018
nad metabolic process GO:0019674 1 0.018
androgen metabolic process GO:0008209 1 0.018
generation of precursor metabolites and energy GO:0006091 42 0.018
purine nucleoside metabolic process GO:0042278 127 0.018
regulation of glucan biosynthetic process GO:0010962 1 0.018
nephron development GO:0072006 3 0.017
regulation of cellular amine metabolic process GO:0033238 3 0.017
establishment of protein localization GO:0045184 163 0.017
connective tissue development GO:0061448 3 0.017
positive regulation of reactive oxygen species metabolic process GO:2000379 0 0.017
positive regulation of cell migration GO:0030335 2 0.017
meiotic cell cycle process GO:1903046 132 0.016
aging GO:0007568 143 0.016
regulation of intracellular signal transduction GO:1902531 236 0.016
response to ketone GO:1901654 34 0.016
ribonucleotide metabolic process GO:0009259 145 0.016
response to wounding GO:0009611 94 0.016
release of sequestered calcium ion into cytosol GO:0051209 1 0.016
spermatogenesis GO:0007283 200 0.016
establishment or maintenance of polarity of follicular epithelium GO:0016334 26 0.016
negative regulation of homeostatic process GO:0032845 2 0.016
phosphatidic acid metabolic process GO:0046473 1 0.016
gene silencing GO:0016458 138 0.016
regulation of ion transport GO:0043269 39 0.016
response to superoxide GO:0000303 3 0.016
lipid metabolic process GO:0006629 121 0.016
response to other organism GO:0051707 293 0.016
ribonucleotide biosynthetic process GO:0009260 28 0.016
cellular ion homeostasis GO:0006873 39 0.016
amine catabolic process GO:0009310 1 0.016
cellular nitrogen compound catabolic process GO:0044270 165 0.016
protein localization GO:0008104 284 0.016
purine nucleobase metabolic process GO:0006144 2 0.016
nephron tubule development GO:0072080 3 0.015
cellular respiration GO:0045333 26 0.015
localization of cell GO:0051674 257 0.015
determination of adult lifespan GO:0008340 137 0.015
kidney development GO:0001822 3 0.015
cation transmembrane transport GO:0098655 88 0.015
amine metabolic process GO:0009308 12 0.015
imaginal disc derived wing morphogenesis GO:0007476 337 0.015
positive regulation of cell communication GO:0010647 250 0.015
regulation of cellular component biogenesis GO:0044087 201 0.015
nuclear division GO:0000280 332 0.015
chemosensory behavior GO:0007635 106 0.015
cytoplasmic transport nurse cell to oocyte GO:0007303 12 0.015
positive regulation of nucleobase containing compound metabolic process GO:0045935 332 0.015
ribose phosphate metabolic process GO:0019693 145 0.015
positive regulation of signal transduction GO:0009967 223 0.015
regulation of secretion by cell GO:1903530 39 0.015
cellular chemical homeostasis GO:0055082 40 0.015
positive regulation of phosphate metabolic process GO:0045937 139 0.015
small molecule catabolic process GO:0044282 21 0.014
synapse organization GO:0050808 196 0.014
nucleotide catabolic process GO:0009166 109 0.014
dendrite morphogenesis GO:0048813 199 0.014
glucan biosynthetic process GO:0009250 2 0.014
mesenchymal cell differentiation GO:0048762 1 0.014
imaginal disc derived appendage development GO:0048737 399 0.014
cellular cation homeostasis GO:0030003 38 0.014
organic acid biosynthetic process GO:0016053 15 0.014
neutral lipid catabolic process GO:0046461 3 0.014
cofactor metabolic process GO:0051186 13 0.014
pteridine containing compound metabolic process GO:0042558 6 0.014
synaptic transmission GO:0007268 288 0.014
amino acid transport GO:0006865 12 0.014
head development GO:0060322 135 0.014
heterocycle catabolic process GO:0046700 166 0.014
glucose metabolic process GO:0006006 5 0.014
positive regulation of sequestering of triglyceride GO:0010890 1 0.014
cellular response to nitrogen compound GO:1901699 51 0.014
nucleoside phosphate biosynthetic process GO:1901293 34 0.013
tissue death GO:0016271 102 0.013
nucleotide biosynthetic process GO:0009165 34 0.013
positive regulation of macromolecule metabolic process GO:0010604 405 0.013
developmental programmed cell death GO:0010623 138 0.013
organic cyclic compound catabolic process GO:1901361 168 0.013
oocyte localization involved in germarium derived egg chamber formation GO:0030720 12 0.013
negative regulation of signal transduction GO:0009968 206 0.013
cellular amino acid biosynthetic process GO:0008652 9 0.013
negative regulation of rna metabolic process GO:0051253 251 0.013
positive regulation of nitrogen compound metabolic process GO:0051173 354 0.013
neutral lipid biosynthetic process GO:0046460 2 0.013
larval development GO:0002164 104 0.012
secondary metabolic process GO:0019748 75 0.012
protein transport GO:0015031 155 0.012
protein complex assembly GO:0006461 200 0.012
regulation of lipid transport GO:0032368 3 0.012
monocarboxylic acid catabolic process GO:0072329 10 0.012
actin cytoskeleton organization GO:0030036 206 0.012
regulation of organelle organization GO:0033043 196 0.012
wing disc morphogenesis GO:0007472 344 0.012
regulation of pole plasm oskar mrna localization GO:0007317 27 0.012
wing disc pattern formation GO:0035222 66 0.012
sister chromatid segregation GO:0000819 92 0.012
histolysis GO:0007559 102 0.012
gastrulation with mouth forming first GO:0001703 36 0.012
response to lipopolysaccharide GO:0032496 4 0.012
ribonucleoside triphosphate biosynthetic process GO:0009201 2 0.012
purine ribonucleotide metabolic process GO:0009150 145 0.012
positive regulation of rna biosynthetic process GO:1902680 266 0.012
mitotic nuclear division GO:0007067 213 0.012
establishment or maintenance of cytoskeleton polarity GO:0030952 44 0.012
fatty acid oxidation GO:0019395 6 0.012
salivary gland cell autophagic cell death GO:0035071 83 0.012
regulation of mapk cascade GO:0043408 92 0.012
developmental pigmentation GO:0048066 68 0.012
metal ion homeostasis GO:0055065 44 0.012
regulation of cellular component movement GO:0051270 42 0.012
purine ribonucleoside metabolic process GO:0046128 127 0.012
actin filament based process GO:0030029 220 0.012
cellular amide metabolic process GO:0043603 80 0.012
single organism membrane organization GO:0044802 93 0.012
response to ecdysone GO:0035075 34 0.012
cellular response to dna damage stimulus GO:0006974 223 0.011
regulation of rna splicing GO:0043484 69 0.011
ribonucleoside triphosphate metabolic process GO:0009199 119 0.011
positive regulation of cell motility GO:2000147 3 0.011
inorganic ion transmembrane transport GO:0098660 73 0.011
purine ribonucleoside triphosphate metabolic process GO:0009205 119 0.011
gastrulation GO:0007369 70 0.011
regulation of molecular function GO:0065009 217 0.011
macromolecular complex assembly GO:0065003 256 0.011
regulation of phosphate metabolic process GO:0019220 210 0.011
nucleobase containing compound transport GO:0015931 56 0.011
cytosolic calcium ion transport GO:0060401 2 0.011
sequestering of calcium ion GO:0051208 5 0.011
exocrine system development GO:0035272 162 0.011
positive regulation of molecular function GO:0044093 136 0.011
age dependent response to oxidative stress GO:0001306 3 0.011
response to hexose GO:0009746 3 0.011
response to water deprivation GO:0009414 4 0.011
organic anion transport GO:0015711 28 0.011
water soluble vitamin metabolic process GO:0006767 1 0.011
regulation of phosphorus metabolic process GO:0051174 210 0.011
positive regulation of macromolecule biosynthetic process GO:0010557 283 0.011
cell motility GO:0048870 251 0.011
organophosphate catabolic process GO:0046434 112 0.011
response to endoplasmic reticulum stress GO:0034976 28 0.011
dna metabolic process GO:0006259 227 0.011
lipid oxidation GO:0034440 7 0.011
acylglycerol biosynthetic process GO:0046463 2 0.010
establishment or maintenance of microtubule cytoskeleton polarity GO:0030951 41 0.010
larval midgut cell programmed cell death GO:0035096 19 0.010
purine containing compound biosynthetic process GO:0072522 30 0.010
purine nucleoside monophosphate biosynthetic process GO:0009127 3 0.010
dorsal ventral pattern formation GO:0009953 133 0.010
regulation of cell maturation GO:1903429 27 0.010
chromosome segregation GO:0007059 157 0.010
positive regulation of biosynthetic process GO:0009891 316 0.010
anterior posterior pattern specification GO:0009952 136 0.010
regulation of intracellular transport GO:0032386 64 0.010
carbohydrate derivative catabolic process GO:1901136 118 0.010
cellular aldehyde metabolic process GO:0006081 10 0.010
adult locomotory behavior GO:0008344 76 0.010
regulation of response to oxidative stress GO:1902882 4 0.010
protein modification process GO:0036211 438 0.010
cellular carbohydrate metabolic process GO:0044262 22 0.010
carboxylic acid catabolic process GO:0046395 16 0.010

Pgd disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in fly and predicted with the fly functional network.

Disease DO term ID Size Probability Func Analog Org
disease of metabolism DOID:0014667 0 0.123
inherited metabolic disorder DOID:655 0 0.123
acquired metabolic disease DOID:0060158 0 0.099
carbohydrate metabolism disease DOID:0050013 0 0.029
glucose metabolism disease DOID:4194 0 0.029
disease of anatomical entity DOID:7 0 0.028
diabetes mellitus DOID:9351 0 0.022
familial hyperlipidemia DOID:1168 0 0.020
lipid metabolism disorder DOID:3146 0 0.020
familial combined hyperlipidemia DOID:13809 0 0.020
musculoskeletal system disease DOID:17 0 0.019
type 2 diabetes mellitus DOID:9352 0 0.017
disease of cellular proliferation DOID:14566 0 0.013
cancer DOID:162 0 0.012
nervous system disease DOID:863 0 0.012
familial hypertriglyceridemia DOID:0050527 0 0.011
muscular disease DOID:0080000 0 0.011