Drosophila melanogaster

32 known processes

hfw (Dmel_CG3095)

halfway

(Aliases: SWI,swi,CT10406,CG3095,Dmel\CG3095,l(1)nfw,l(1)2Bf,EG:171E4.2)

hfw biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
ion transmembrane transport GO:0034220 122 0.085
positive regulation of biosynthetic process GO:0009891 316 0.074
pigment metabolic process GO:0042440 84 0.070
organonitrogen compound metabolic process GO:1901564 318 0.068
positive regulation of rna metabolic process GO:0051254 271 0.063
single organism biosynthetic process GO:0044711 206 0.061
wing disc morphogenesis GO:0007472 344 0.061
negative regulation of signaling GO:0023057 219 0.059
reproductive behavior GO:0019098 122 0.057
regulation of response to oxidative stress GO:1902882 4 0.057
positive regulation of transcription from rna polymerase ii promoter GO:0045944 204 0.055
transcription from rna polymerase ii promoter GO:0006366 368 0.055
extrinsic apoptotic signaling pathway GO:0097191 1 0.050
regulation of transcription from rna polymerase ii promoter GO:0006357 378 0.049
lipid metabolic process GO:0006629 121 0.048
appendage development GO:0048736 401 0.047
regulation of cellular response to stress GO:0080135 89 0.047
body morphogenesis GO:0010171 2 0.044
eye pigment metabolic process GO:0042441 33 0.044
transmembrane transport GO:0055085 139 0.044
cellular macromolecule localization GO:0070727 220 0.044
cellular response to abiotic stimulus GO:0071214 58 0.043
ommochrome metabolic process GO:0046152 19 0.042
response to wounding GO:0009611 94 0.042
response to glucose GO:0009749 2 0.042
defense response GO:0006952 300 0.042
lipid modification GO:0030258 24 0.042
single organism intracellular transport GO:1902582 207 0.041
post embryonic appendage morphogenesis GO:0035120 385 0.041
phosphorylation GO:0016310 294 0.039
response to organic substance GO:0010033 284 0.038
imaginal disc derived wing morphogenesis GO:0007476 337 0.038
cell proliferation GO:0008283 299 0.035
positive regulation of gene expression GO:0010628 290 0.035
negative regulation of wnt signaling pathway GO:0030178 28 0.035
immune system process GO:0002376 347 0.034
catabolic process GO:0009056 409 0.033
regulation of immune response GO:0050776 118 0.033
regulation of response to stress GO:0080134 200 0.033
positive regulation of nitrogen compound metabolic process GO:0051173 354 0.033
regulation of adult chitin containing cuticle pigmentation GO:0048082 13 0.033
regulation of synapse structure and activity GO:0050803 128 0.032
ocellus pigmentation GO:0033060 19 0.032
synaptic transmission GO:0007268 288 0.031
rna processing GO:0006396 147 0.031
positive regulation of nucleic acid templated transcription GO:1903508 266 0.031
defense response to gram negative bacterium GO:0050829 94 0.031
protein localization GO:0008104 284 0.031
secondary metabolic process GO:0019748 75 0.031
developmental pigmentation GO:0048066 68 0.031
cellular protein modification process GO:0006464 438 0.030
imaginal disc derived appendage morphogenesis GO:0035114 395 0.030
pigment metabolic process involved in developmental pigmentation GO:0043324 33 0.030
positive regulation of nf kappab import into nucleus GO:0042346 1 0.030
negative regulation of response to stimulus GO:0048585 258 0.030
developmental growth GO:0048589 280 0.030
response to hexose GO:0009746 3 0.029
small molecule metabolic process GO:0044281 305 0.029
response to biotic stimulus GO:0009607 294 0.029
single organism membrane organization GO:0044802 93 0.029
mapk cascade GO:0000165 107 0.029
nephron development GO:0072006 3 0.029
regulation of antimicrobial humoral response GO:0002759 50 0.028
positive regulation of rna biosynthetic process GO:1902680 266 0.028
monocarboxylic acid transport GO:0015718 3 0.028
carbohydrate metabolic process GO:0005975 82 0.028
defense response to other organism GO:0098542 225 0.028
single organism cellular localization GO:1902580 180 0.027
regulation of growth GO:0040008 233 0.027
membrane organization GO:0061024 112 0.027
pigment biosynthetic process GO:0046148 36 0.027
regulation of endopeptidase activity GO:0052548 36 0.027
connective tissue development GO:0061448 3 0.027
carboxylic acid metabolic process GO:0019752 92 0.027
protein modification process GO:0036211 438 0.027
regulation of cell differentiation GO:0045595 302 0.027
positive regulation of cellular biosynthetic process GO:0031328 316 0.027
cell death GO:0008219 279 0.027
defense response to bacterium GO:0042742 178 0.026
organic acid metabolic process GO:0006082 103 0.026
developmental maturation GO:0021700 172 0.026
regulation of synapse organization GO:0050807 110 0.026
cellular lipid metabolic process GO:0044255 83 0.026
growth GO:0040007 359 0.026
regulation of epithelial cell proliferation GO:0050678 4 0.026
response to bacterium GO:0009617 198 0.026
eye pigment biosynthetic process GO:0006726 32 0.026
secondary metabolite biosynthetic process GO:0044550 24 0.026
positive regulation of defense response GO:0031349 59 0.025
maintenance of gastrointestinal epithelium GO:0030277 3 0.025
stress activated protein kinase signaling cascade GO:0031098 55 0.025
oxoacid metabolic process GO:0043436 103 0.025
regulation of immune system process GO:0002682 176 0.025
ion transport GO:0006811 145 0.024
response to other organism GO:0051707 293 0.024
epithelial cell differentiation GO:0030855 322 0.024
regulation of cellular localization GO:0060341 136 0.024
response to monosaccharide GO:0034284 4 0.023
signal transduction by phosphorylation GO:0023014 107 0.023
cellular catabolic process GO:0044248 372 0.023
positive regulation of signaling GO:0023056 243 0.023
intracellular transport GO:0046907 228 0.023
regulation of response to external stimulus GO:0032101 115 0.023
positive regulation of cell communication GO:0010647 250 0.022
positive regulation of phosphate metabolic process GO:0045937 139 0.022
peptide biosynthetic process GO:0043043 42 0.022
regulation of transmembrane transport GO:0034762 27 0.022
regulation of multicellular organismal development GO:2000026 414 0.022
appendage morphogenesis GO:0035107 397 0.022
synapse organization GO:0050808 196 0.022
sarcomere organization GO:0045214 26 0.022
camera type eye development GO:0043010 4 0.022
cation transport GO:0006812 110 0.021
protein phosphorylation GO:0006468 169 0.021
establishment of localization in cell GO:0051649 402 0.021
positive regulation of calcium ion transport GO:0051928 4 0.021
regulation of phosphate metabolic process GO:0019220 210 0.021
positive regulation of macromolecule biosynthetic process GO:0010557 283 0.021
regulation of nf kappab import into nucleus GO:0042345 1 0.021
embryo development ending in birth or egg hatching GO:0009792 152 0.021
response to dsrna GO:0043331 15 0.021
cellular amino acid metabolic process GO:0006520 61 0.021
metal ion homeostasis GO:0055065 44 0.020
regulation of catalytic activity GO:0050790 185 0.020
cation transmembrane transport GO:0098655 88 0.020
pattern recognition receptor signaling pathway GO:0002221 2 0.020
stress activated mapk cascade GO:0051403 52 0.020
regulation of programmed cell death GO:0043067 152 0.020
negative regulation of signal transduction GO:0009968 206 0.020
positive regulation of macromolecule metabolic process GO:0010604 405 0.020
regulation of stress activated protein kinase signaling cascade GO:0070302 42 0.020
substrate adhesion dependent cell spreading GO:0034446 2 0.020
regulation of mapk cascade GO:0043408 92 0.020
response to lipopolysaccharide GO:0032496 4 0.019
establishment of protein localization GO:0045184 163 0.019
wound healing spreading of epidermal cells GO:0035313 1 0.019
regulation of chitin based cuticle tanning GO:0007564 14 0.019
regulation of defense response GO:0031347 102 0.019
equator specification GO:0045317 4 0.019
humoral immune response GO:0006959 117 0.019
gland morphogenesis GO:0022612 145 0.019
regulation of imaginal disc growth GO:0045570 26 0.019
biological adhesion GO:0022610 138 0.019
response to external biotic stimulus GO:0043207 293 0.019
nephron tubule development GO:0072080 3 0.019
positive regulation of cell motility GO:2000147 3 0.019
negative regulation of gene expression GO:0010629 387 0.018
organic substance transport GO:0071702 257 0.018
molting cycle chitin based cuticle GO:0007591 56 0.018
establishment or maintenance of cell polarity GO:0007163 167 0.018
cellular ketone metabolic process GO:0042180 24 0.018
positive regulation of developmental process GO:0051094 143 0.018
tissue morphogenesis GO:0048729 297 0.018
positive regulation of catabolic process GO:0009896 105 0.018
gland development GO:0048732 191 0.018
purine ribonucleotide metabolic process GO:0009150 145 0.018
innate immune response activating signal transduction GO:0002758 2 0.018
ocellus pigment metabolic process GO:0046158 19 0.018
wnt signaling pathway GO:0016055 98 0.018
positive regulation of immune response GO:0050778 63 0.018
regulation of protein localization GO:0032880 76 0.018
determination of adult lifespan GO:0008340 137 0.017
regionalization GO:0003002 416 0.017
regulation of phosphorus metabolic process GO:0051174 210 0.017
negative regulation of multicellular organismal process GO:0051241 142 0.017
nf kappab import into nucleus GO:0042348 1 0.017
carbohydrate derivative biosynthetic process GO:1901137 85 0.017
wound healing GO:0042060 75 0.017
positive regulation of transport GO:0051050 92 0.017
single organism carbohydrate metabolic process GO:0044723 72 0.017
jnk cascade GO:0007254 50 0.017
regulation of cell death GO:0010941 173 0.017
camera type eye morphogenesis GO:0048593 2 0.016
positive regulation of cell migration GO:0030335 2 0.016
organelle assembly GO:0070925 198 0.016
cytoplasmic transport GO:0016482 130 0.016
chemical homeostasis GO:0048878 92 0.016
regulation of meiosis GO:0040020 3 0.016
regulation of intracellular signal transduction GO:1902531 236 0.016
imaginal disc growth GO:0007446 37 0.016
cell adhesion GO:0007155 136 0.016
activation of innate immune response GO:0002218 4 0.016
innate immune response GO:0045087 144 0.016
positive regulation of cellular catabolic process GO:0031331 95 0.016
mrna metabolic process GO:0016071 124 0.016
apoptotic process GO:0006915 159 0.016
regulation of developmental growth GO:0048638 174 0.016
chitin based cuticle sclerotization GO:0007593 19 0.016
inorganic ion transmembrane transport GO:0098660 73 0.016
morphogenesis of an epithelium GO:0002009 276 0.016
positive regulation of molecular function GO:0044093 136 0.016
positive regulation of nucleocytoplasmic transport GO:0046824 24 0.016
mitotic cell cycle embryonic GO:0045448 38 0.016
i kappab phosphorylation GO:0007252 3 0.016
necrotic cell death GO:0070265 1 0.016
cellular protein localization GO:0034613 160 0.016
positive regulation of signal transduction GO:0009967 223 0.015
hematopoietic progenitor cell differentiation GO:0002244 1 0.015
cellular response to sterol depletion GO:0071501 3 0.015
response to nitrogen compound GO:1901698 90 0.015
negative regulation of protein metabolic process GO:0051248 85 0.015
ommochrome biosynthetic process GO:0006727 19 0.015
regulation of organ morphogenesis GO:2000027 78 0.015
regulation of humoral immune response GO:0002920 51 0.015
respiratory system development GO:0060541 213 0.015
intracellular signal transduction GO:0035556 300 0.015
positive regulation of response to stimulus GO:0048584 323 0.015
regulation of innate immune response GO:0045088 71 0.015
cellular response to organic substance GO:0071310 132 0.015
organelle fission GO:0048285 340 0.015
programmed cell death GO:0012501 257 0.015
negative regulation of cell communication GO:0010648 223 0.015
reproductive system development GO:0061458 74 0.015
cellular response to lipopolysaccharide GO:0071222 3 0.015
response to organophosphorus GO:0046683 2 0.015
homeostatic process GO:0042592 199 0.015
positive regulation of phosphorus metabolic process GO:0010562 139 0.015
mesenchymal cell differentiation GO:0048762 1 0.014
metal ion transport GO:0030001 74 0.014
hindgut development GO:0061525 58 0.014
regulation of cellular amine metabolic process GO:0033238 3 0.014
positive regulation of transcription dna templated GO:0045893 266 0.014
positive regulation of phosphorylation GO:0042327 87 0.014
death GO:0016265 284 0.014
regulation of intracellular protein transport GO:0033157 46 0.014
negative regulation of cellular protein metabolic process GO:0032269 85 0.014
positive regulation of nucleobase containing compound metabolic process GO:0045935 332 0.014
nucleocytoplasmic transport GO:0006913 72 0.014
regulation of localization GO:0032879 275 0.014
cellular divalent inorganic cation homeostasis GO:0072503 23 0.014
regulation of i kappab kinase nf kappab signaling GO:0043122 2 0.014
regulation of cell cycle GO:0051726 291 0.014
positive regulation of reactive oxygen species metabolic process GO:2000379 0 0.014
cellular response to hexose stimulus GO:0071331 1 0.014
aging GO:0007568 143 0.014
adult chitin containing cuticle pigmentation GO:0048085 16 0.014
regulation of protein metabolic process GO:0051246 256 0.014
retina development in camera type eye GO:0060041 4 0.014
regulation of peptidase activity GO:0052547 39 0.013
immune response regulating signaling pathway GO:0002764 2 0.013
kidney epithelium development GO:0072073 3 0.013
nephron morphogenesis GO:0072028 3 0.013
eye pigmentation GO:0048069 43 0.013
negative regulation of cellular macromolecule biosynthetic process GO:2000113 267 0.013
epiboly involved in wound healing GO:0090505 2 0.013
taxis GO:0042330 304 0.013
regulation of autophagy GO:0010506 62 0.013
outflow tract morphogenesis GO:0003151 4 0.013
immune response GO:0006955 246 0.013
cellular component assembly involved in morphogenesis GO:0010927 151 0.013
phagocytosis GO:0006909 215 0.013
regulation of stress activated mapk cascade GO:0032872 41 0.013
regulation of cellular ketone metabolic process GO:0010565 3 0.013
neuron projection guidance GO:0097485 241 0.013
eye morphogenesis GO:0048592 260 0.013
positive regulation of jun kinase activity GO:0043507 4 0.013
endomembrane system organization GO:0010256 119 0.013
cellular response to mechanical stimulus GO:0071260 2 0.013
eye development GO:0001654 323 0.013
protein secretion GO:0009306 45 0.013
regulation of cellular amino acid metabolic process GO:0006521 0 0.013
ocellus pigment biosynthetic process GO:0008055 19 0.013
organic substance catabolic process GO:1901575 308 0.013
macromolecular complex assembly GO:0065003 256 0.013
multi organism behavior GO:0051705 175 0.013
regulation of cellular protein metabolic process GO:0032268 243 0.013
actin cytoskeleton organization GO:0030036 206 0.013
cuticle pigmentation GO:0048067 22 0.013
mrna processing GO:0006397 104 0.013
inositol lipid mediated signaling GO:0048017 4 0.013
regulation of jnk cascade GO:0046328 40 0.013
protein complex biogenesis GO:0070271 201 0.013
adult behavior GO:0030534 137 0.013
regulation of wnt signaling pathway GO:0030111 68 0.013
developmental programmed cell death GO:0010623 138 0.012
positive regulation of immune system process GO:0002684 68 0.012
cell migration GO:0016477 238 0.012
regulation of ion transport GO:0043269 39 0.012
regulation of catabolic process GO:0009894 170 0.012
salivary gland morphogenesis GO:0007435 145 0.012
morphogenesis of a branching epithelium GO:0061138 45 0.012
regulation of molecular function GO:0065009 217 0.012
intracellular protein transport GO:0006886 104 0.012
secretion GO:0046903 109 0.012
response to alcohol GO:0097305 95 0.012
response to organic cyclic compound GO:0014070 89 0.012
digestive tract morphogenesis GO:0048546 127 0.012
regulation of transport GO:0051049 181 0.012
melanin metabolic process GO:0006582 47 0.012
regulation of phosphorylation GO:0042325 147 0.012
neuromuscular junction development GO:0007528 149 0.012
regulation of hormone levels GO:0010817 40 0.012
salivary gland histolysis GO:0035070 88 0.012
stem cell proliferation GO:0072089 88 0.012
positive regulation of mapk cascade GO:0043410 63 0.012
regulation of response to wounding GO:1903034 19 0.012
negative regulation of rna metabolic process GO:0051253 251 0.012
cellular amide metabolic process GO:0043603 80 0.012
regulation of hydrolase activity GO:0051336 97 0.012
protein heterooligomerization GO:0051291 4 0.012
regulation of cellular component biogenesis GO:0044087 201 0.012
negative regulation of rna biosynthetic process GO:1902679 240 0.012
dorsal ventral axis specification GO:0009950 66 0.012
kidney development GO:0001822 3 0.012
positive regulation of intracellular signal transduction GO:1902533 116 0.012
positive regulation of cellular amino acid metabolic process GO:0045764 0 0.012
chemotaxis GO:0006935 249 0.012
gene silencing GO:0016458 138 0.012
collateral sprouting GO:0048668 3 0.011
endocytosis GO:0006897 310 0.011
regulation of cell proliferation GO:0042127 163 0.011
regulation of nervous system development GO:0051960 248 0.011
negative regulation of cellular metabolic process GO:0031324 382 0.011
kidney morphogenesis GO:0060993 3 0.011
response to abiotic stimulus GO:0009628 341 0.011
nuclear transport GO:0051169 72 0.011
signal release GO:0023061 49 0.011
positive regulation of protein localization to nucleus GO:1900182 21 0.011
negative regulation of phosphorus metabolic process GO:0010563 45 0.011
nephron tubule morphogenesis GO:0072078 3 0.011
regulation of establishment of protein localization GO:0070201 61 0.011
nephron epithelium development GO:0072009 3 0.011
peptide metabolic process GO:0006518 80 0.011
response to radiation GO:0009314 155 0.011
leg disc morphogenesis GO:0007478 80 0.011
response to extracellular stimulus GO:0009991 116 0.011
phenol containing compound metabolic process GO:0018958 57 0.011
reproductive structure development GO:0048608 74 0.011
negative regulation of nucleic acid templated transcription GO:1903507 240 0.011
cellular response to biotic stimulus GO:0071216 4 0.011
cellular response to molecule of bacterial origin GO:0071219 3 0.011
positive regulation of protein import into nucleus GO:0042307 21 0.011
amine metabolic process GO:0009308 12 0.011
ras protein signal transduction GO:0007265 88 0.011
embryonic axis specification GO:0000578 107 0.011
cellular response to carbohydrate stimulus GO:0071322 4 0.011
organic cyclic compound catabolic process GO:1901361 168 0.011
regulation of synapse assembly GO:0051963 94 0.011
cell aging GO:0007569 2 0.011
muscle cell migration GO:0014812 3 0.011
positive regulation of lipid metabolic process GO:0045834 4 0.011
cellular homeostasis GO:0019725 80 0.011
protein complex localization GO:0031503 4 0.011
embryonic hindgut morphogenesis GO:0048619 48 0.011
positive regulation of developmental growth GO:0048639 62 0.011
negative regulation of cell proliferation GO:0008285 69 0.011
epiboly GO:0090504 2 0.011
defense response to virus GO:0051607 23 0.011
epithelial cell development GO:0002064 274 0.011
imaginal disc derived appendage development GO:0048737 399 0.011
positive regulation of compound eye retinal cell programmed cell death GO:0046672 9 0.011
cellular ion homeostasis GO:0006873 39 0.011
cellular response to dna damage stimulus GO:0006974 223 0.010
muscle attachment GO:0016203 36 0.010
response to ionizing radiation GO:0010212 32 0.010
leg disc development GO:0035218 92 0.010
protein complex assembly GO:0006461 200 0.010
regulation of hemocyte differentiation GO:0045610 22 0.010
larval development GO:0002164 104 0.010
spermatogenesis GO:0007283 200 0.010
imaginal disc derived leg segmentation GO:0036011 26 0.010
substrate dependent cell migration GO:0006929 3 0.010
anterior posterior axis specification embryo GO:0008595 103 0.010
multi multicellular organism process GO:0044706 123 0.010
olfactory behavior GO:0042048 97 0.010
positive regulation of i kappab kinase nf kappab signaling GO:0043123 1 0.010
cellular response to chemical stimulus GO:0070887 199 0.010
positive regulation of growth GO:0045927 75 0.010
negative regulation of catalytic activity GO:0043086 42 0.010
carbohydrate derivative metabolic process GO:1901135 217 0.010
antimicrobial peptide production GO:0002775 46 0.010
segmentation GO:0035282 207 0.010
regulation of cellular catabolic process GO:0031329 157 0.010
anion homeostasis GO:0055081 3 0.010
negative regulation of defense response GO:0031348 35 0.010
skeletal muscle fiber development GO:0048741 3 0.010
nephron epithelium morphogenesis GO:0072088 3 0.010

hfw disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in fly and predicted with the fly functional network.

Disease DO term ID Size Probability Func Analog Org
disease of metabolism DOID:0014667 0 0.034
disease of anatomical entity DOID:7 0 0.034
inherited metabolic disorder DOID:655 0 0.020
nervous system disease DOID:863 0 0.020
cancer DOID:162 0 0.015
disease of cellular proliferation DOID:14566 0 0.015