Drosophila melanogaster

183 known processes

RhoGEF4 (Dmel_CG8606)

CG8606 gene product from transcript CG8606-RA

(Aliases: CG8606,DRhoGEF4,Dmel\CG8606)

RhoGEF4 biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
chromosome organization GO:0051276 360 0.186
small molecule metabolic process GO:0044281 305 0.156
regulation of intracellular signal transduction GO:1902531 236 0.151
purine ribonucleoside metabolic process GO:0046128 127 0.148
organonitrogen compound metabolic process GO:1901564 318 0.120
regulation of cell cycle process GO:0010564 181 0.117
organelle fission GO:0048285 340 0.098
intracellular signal transduction GO:0035556 300 0.091
negative regulation of nucleobase containing compound metabolic process GO:0045934 261 0.090
heterocycle catabolic process GO:0046700 166 0.087
purine ribonucleoside triphosphate metabolic process GO:0009205 119 0.082
spindle organization GO:0007051 253 0.081
regulation of gene expression epigenetic GO:0040029 128 0.081
mitotic cytokinesis GO:0000281 50 0.077
negative regulation of cellular macromolecule biosynthetic process GO:2000113 267 0.074
organic acid metabolic process GO:0006082 103 0.074
mitotic nuclear division GO:0007067 213 0.073
organophosphate metabolic process GO:0019637 195 0.069
cytoskeleton dependent cytokinesis GO:0061640 81 0.068
purine nucleotide metabolic process GO:0006163 146 0.067
single organism catabolic process GO:0044712 228 0.066
ribonucleotide metabolic process GO:0009259 145 0.064
mitotic spindle organization GO:0007052 220 0.063
organic cyclic compound catabolic process GO:1901361 168 0.061
negative regulation of gene expression GO:0010629 387 0.059
negative regulation of signaling GO:0023057 219 0.059
positive regulation of response to stimulus GO:0048584 323 0.057
nucleoside metabolic process GO:0009116 127 0.056
negative regulation of macromolecule biosynthetic process GO:0010558 270 0.055
response to abiotic stimulus GO:0009628 341 0.055
chromosome segregation GO:0007059 157 0.054
establishment of localization in cell GO:0051649 402 0.053
regulation of phosphorus metabolic process GO:0051174 210 0.052
nucleoside phosphate metabolic process GO:0006753 162 0.051
cell division GO:0051301 248 0.049
negative regulation of nitrogen compound metabolic process GO:0051172 265 0.049
glycosyl compound catabolic process GO:1901658 112 0.049
negative regulation of biosynthetic process GO:0009890 277 0.048
ribonucleoside metabolic process GO:0009119 127 0.048
cellular nitrogen compound catabolic process GO:0044270 165 0.048
organic substance catabolic process GO:1901575 308 0.046
regulation of cell cycle GO:0051726 291 0.045
regulation of programmed cell death GO:0043067 152 0.045
negative regulation of transcription dna templated GO:0045892 237 0.044
nucleoside catabolic process GO:0009164 112 0.044
cytokinesis GO:0000910 90 0.044
regulation of phosphorylation GO:0042325 147 0.043
single organism behavior GO:0044708 391 0.043
regulation of phosphate metabolic process GO:0019220 210 0.043
negative regulation of cellular biosynthetic process GO:0031327 277 0.042
purine ribonucleotide metabolic process GO:0009150 145 0.042
body morphogenesis GO:0010171 2 0.041
regulation of mitotic cell cycle GO:0007346 190 0.040
cell death GO:0008219 279 0.040
nucleotide metabolic process GO:0009117 161 0.040
phosphorylation GO:0016310 294 0.039
response to organic substance GO:0010033 284 0.039
positive regulation of signal transduction GO:0009967 223 0.038
nucleobase containing compound catabolic process GO:0034655 165 0.038
organonitrogen compound catabolic process GO:1901565 128 0.037
purine containing compound metabolic process GO:0072521 155 0.037
nucleotide catabolic process GO:0009166 109 0.037
purine nucleoside triphosphate catabolic process GO:0009146 108 0.036
ribonucleoside triphosphate catabolic process GO:0009203 108 0.036
sister chromatid segregation GO:0000819 92 0.035
imaginal disc derived appendage development GO:0048737 399 0.035
nuclear division GO:0000280 332 0.034
regionalization GO:0003002 416 0.034
organic substance transport GO:0071702 257 0.034
regulation of nervous system development GO:0051960 248 0.034
carbohydrate derivative metabolic process GO:1901135 217 0.034
negative regulation of nucleic acid templated transcription GO:1903507 240 0.034
meiosis i GO:0007127 59 0.032
ras protein signal transduction GO:0007265 88 0.032
compound eye development GO:0048749 307 0.032
glycosyl compound metabolic process GO:1901657 127 0.032
mitotic cell cycle phase transition GO:0044772 138 0.032
purine nucleotide catabolic process GO:0006195 109 0.032
regulation of catabolic process GO:0009894 170 0.032
purine containing compound catabolic process GO:0072523 112 0.032
axonogenesis GO:0007409 290 0.031
positive regulation of cell communication GO:0010647 250 0.031
regulation of molecular function GO:0065009 217 0.031
positive regulation of phosphate metabolic process GO:0045937 139 0.030
regulation of response to stress GO:0080134 200 0.030
immune system process GO:0002376 347 0.030
post embryonic appendage morphogenesis GO:0035120 385 0.030
negative regulation of cell cycle process GO:0010948 109 0.030
purine nucleoside triphosphate metabolic process GO:0009144 119 0.030
signal transduction by phosphorylation GO:0023014 107 0.030
negative regulation of rna metabolic process GO:0051253 251 0.029
regulation of mapk cascade GO:0043408 92 0.029
mitotic sister chromatid separation GO:0051306 30 0.029
nucleobase containing small molecule metabolic process GO:0055086 174 0.028
regulation of multicellular organismal development GO:2000026 414 0.028
regulation of cellular protein metabolic process GO:0032268 243 0.028
purine nucleoside metabolic process GO:0042278 127 0.028
enzyme linked receptor protein signaling pathway GO:0007167 179 0.027
positive regulation of phosphorus metabolic process GO:0010562 139 0.027
cellular catabolic process GO:0044248 372 0.027
ribose phosphate metabolic process GO:0019693 145 0.026
chromosome separation GO:0051304 42 0.026
negative regulation of cell communication GO:0010648 223 0.026
regulation of proteolysis GO:0030162 87 0.026
death GO:0016265 284 0.026
catabolic process GO:0009056 409 0.026
regulation of cytoskeleton organization GO:0051493 89 0.026
negative regulation of cell death GO:0060548 81 0.026
eye morphogenesis GO:0048592 260 0.025
purine nucleoside catabolic process GO:0006152 112 0.025
ribonucleotide catabolic process GO:0009261 109 0.025
negative regulation of cellular metabolic process GO:0031324 382 0.025
regulation of neurogenesis GO:0050767 158 0.025
response to oxygen containing compound GO:1901700 200 0.024
positive regulation of molecular function GO:0044093 136 0.024
cytoplasmic transport GO:0016482 130 0.024
camera type eye development GO:0043010 4 0.024
dna repair GO:0006281 54 0.023
positive regulation of signaling GO:0023056 243 0.023
purine ribonucleoside monophosphate metabolic process GO:0009167 50 0.023
small gtpase mediated signal transduction GO:0007264 88 0.023
organophosphate catabolic process GO:0046434 112 0.023
transcription from rna polymerase ii promoter GO:0006366 368 0.023
regulation of protein metabolic process GO:0051246 256 0.022
mitotic sister chromatid segregation GO:0000070 87 0.022
purine ribonucleotide catabolic process GO:0009154 109 0.022
protein complex biogenesis GO:0070271 201 0.022
oxoacid metabolic process GO:0043436 103 0.022
positive regulation of gene expression GO:0010628 290 0.022
positive regulation of macromolecule metabolic process GO:0010604 405 0.021
regulation of cell differentiation GO:0045595 302 0.021
chromatin organization GO:0006325 207 0.021
meiotic dna double strand break formation GO:0042138 1 0.021
aromatic compound catabolic process GO:0019439 166 0.021
regulation of apoptotic process GO:0042981 130 0.021
single organism biosynthetic process GO:0044711 206 0.020
centrosome cycle GO:0007098 137 0.020
purine ribonucleoside triphosphate catabolic process GO:0009207 108 0.020
negative regulation of signal transduction GO:0009968 206 0.020
carboxylic acid metabolic process GO:0019752 92 0.020
nucleoside triphosphate catabolic process GO:0009143 108 0.020
nucleoside phosphate catabolic process GO:1901292 110 0.020
cell proliferation GO:0008283 299 0.020
positive regulation of phosphorylation GO:0042327 87 0.020
ribonucleoside catabolic process GO:0042454 112 0.020
establishment or maintenance of cell polarity GO:0007163 167 0.019
regulation of transcription from rna polymerase ii promoter GO:0006357 378 0.019
eye development GO:0001654 323 0.019
cellularization GO:0007349 90 0.019
photoreceptor cell differentiation GO:0046530 170 0.019
intracellular transport GO:0046907 228 0.019
regulation of catalytic activity GO:0050790 185 0.018
embryonic heart tube development GO:0035050 22 0.018
negative regulation of response to stimulus GO:0048585 258 0.018
regulation of ras protein signal transduction GO:0046578 93 0.018
establishment of spindle orientation GO:0051294 18 0.018
negative regulation of cellular component organization GO:0051129 108 0.018
cellular response to biotic stimulus GO:0071216 4 0.018
dna packaging GO:0006323 91 0.018
negative regulation of mitotic cell cycle GO:0045930 109 0.017
response to temperature stimulus GO:0009266 106 0.017
cell cycle phase transition GO:0044770 140 0.017
negative regulation of programmed cell death GO:0043069 72 0.017
positive regulation of transcription from rna polymerase ii promoter GO:0045944 204 0.017
regulation of cellular response to stress GO:0080135 89 0.017
positive regulation of nucleic acid templated transcription GO:1903508 266 0.017
regulation of mitotic cell cycle phase transition GO:1901990 130 0.017
appendage morphogenesis GO:0035107 397 0.017
positive regulation of nucleobase containing compound metabolic process GO:0045935 332 0.017
developmental growth GO:0048589 280 0.017
regulation of cell development GO:0060284 215 0.016
peptidyl amino acid modification GO:0018193 105 0.016
regulation of protein modification process GO:0031399 112 0.016
cellular protein complex disassembly GO:0043624 35 0.016
actin cytoskeleton organization GO:0030036 206 0.016
imaginal disc pattern formation GO:0007447 91 0.016
female meiotic division GO:0007143 70 0.016
cellular protein modification process GO:0006464 438 0.016
purine nucleoside monophosphate metabolic process GO:0009126 50 0.016
ribonucleoside monophosphate metabolic process GO:0009161 51 0.016
negative regulation of cell cycle phase transition GO:1901988 103 0.016
embryo development ending in birth or egg hatching GO:0009792 152 0.016
chromatin modification GO:0016568 147 0.015
compound eye morphogenesis GO:0001745 249 0.015
regulation of cell cycle phase transition GO:1901987 130 0.015
sensory organ morphogenesis GO:0090596 260 0.015
ribonucleoside triphosphate metabolic process GO:0009199 119 0.015
single organism intracellular transport GO:1902582 207 0.015
regulation of cell division GO:0051302 72 0.015
mitotic chromosome condensation GO:0007076 22 0.015
apoptotic process GO:0006915 159 0.015
regulation of cell death GO:0010941 173 0.015
carbohydrate derivative catabolic process GO:1901136 118 0.014
endocytosis GO:0006897 310 0.014
regulation of transferase activity GO:0051338 58 0.014
negative regulation of organelle organization GO:0010639 56 0.014
negative regulation of transcription from rna polymerase ii promoter GO:0000122 119 0.014
dorsal ventral pattern formation GO:0009953 133 0.014
cellular macromolecule localization GO:0070727 220 0.014
protein maturation GO:0051604 71 0.014
regulation of mitosis GO:0007088 56 0.014
imaginal disc derived appendage morphogenesis GO:0035114 395 0.014
embryonic morphogenesis GO:0048598 206 0.014
cellular response to dna damage stimulus GO:0006974 223 0.013
lateral inhibition GO:0046331 206 0.013
phagocytosis GO:0006909 215 0.013
spindle assembly involved in mitosis GO:0090307 50 0.013
leg disc development GO:0035218 92 0.013
spindle assembly GO:0051225 80 0.013
stem cell differentiation GO:0048863 117 0.013
atp metabolic process GO:0046034 49 0.013
cellular protein localization GO:0034613 160 0.013
camera type eye morphogenesis GO:0048593 2 0.013
negative regulation of rna biosynthetic process GO:1902679 240 0.013
macromolecular complex assembly GO:0065003 256 0.013
mapk cascade GO:0000165 107 0.013
response to lipopolysaccharide GO:0032496 4 0.013
cellular component assembly involved in morphogenesis GO:0010927 151 0.013
protein phosphorylation GO:0006468 169 0.013
regulation of cellular amine metabolic process GO:0033238 3 0.012
regulation of cellular amino acid metabolic process GO:0006521 0 0.012
negative regulation of gene expression epigenetic GO:0045814 77 0.012
cellular amino acid metabolic process GO:0006520 61 0.012
negative regulation of mitotic cell cycle phase transition GO:1901991 103 0.012
cellular ketone metabolic process GO:0042180 24 0.012
response to heat GO:0009408 63 0.012
metaphase anaphase transition of cell cycle GO:0044784 28 0.012
protein localization GO:0008104 284 0.012
meiotic nuclear division GO:0007126 151 0.012
positive regulation of transferase activity GO:0051347 26 0.012
purine ribonucleoside catabolic process GO:0046130 112 0.012
amine metabolic process GO:0009308 12 0.012
regulation of mitotic sister chromatid segregation GO:0033047 28 0.012
protein modification process GO:0036211 438 0.012
protein transport GO:0015031 155 0.012
positive regulation of catalytic activity GO:0043085 118 0.012
regulation of response to dna damage stimulus GO:2001020 23 0.011
dna metabolic process GO:0006259 227 0.011
positive regulation of hydrolase activity GO:0051345 78 0.011
positive regulation of intracellular signal transduction GO:1902533 116 0.011
negative regulation of chromosome segregation GO:0051985 14 0.011
nucleoside triphosphate metabolic process GO:0009141 120 0.011
ubiquitin dependent protein catabolic process GO:0006511 78 0.011
nuclear dna replication GO:0033260 1 0.011
single organism cellular localization GO:1902580 180 0.011
ribonucleoside monophosphate catabolic process GO:0009158 39 0.011
cellular response to chemical stimulus GO:0070887 199 0.011
negative regulation of cell cycle GO:0045786 116 0.011
compound eye photoreceptor cell differentiation GO:0001751 140 0.011
neurological system process GO:0050877 358 0.011
positive regulation of ras protein signal transduction GO:0046579 43 0.011
transmembrane receptor protein tyrosine kinase signaling pathway GO:0007169 116 0.011
response to extracellular stimulus GO:0009991 116 0.011
regulation of cellular ketone metabolic process GO:0010565 3 0.011
negative regulation of proteasomal protein catabolic process GO:1901799 16 0.011
centrosome organization GO:0051297 163 0.011
meiotic cell cycle process GO:1903046 132 0.011
microtubule based movement GO:0007018 51 0.011
growth GO:0040007 359 0.011
g1 s transition of mitotic cell cycle GO:0000082 31 0.011
negative regulation of apoptotic process GO:0043066 63 0.011
response to radiation GO:0009314 155 0.010
adult behavior GO:0030534 137 0.010
negative regulation of cellular protein metabolic process GO:0032269 85 0.010
positive regulation of nitrogen compound metabolic process GO:0051173 354 0.010
response to biotic stimulus GO:0009607 294 0.010
eye photoreceptor cell differentiation GO:0001754 145 0.010
cell cycle g1 s phase transition GO:0044843 31 0.010
skeletal muscle fiber development GO:0048741 3 0.010
protein processing GO:0016485 68 0.010
epithelial tube morphogenesis GO:0060562 88 0.010
mitotic cell cycle checkpoint GO:0007093 88 0.010
pharynx development GO:0060465 1 0.010

RhoGEF4 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in fly and predicted with the fly functional network.

Disease DO term ID Size Probability Func Analog Org
disease of anatomical entity DOID:7 0 0.043
disease of cellular proliferation DOID:14566 0 0.012