Drosophila melanogaster

5 known processes

ERR (Dmel_CG7404)

estrogen-related receptor

(Aliases: NR3B4,CG7404,Dmel\CG7404,dERR)

ERR biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
negative regulation of nucleobase containing compound metabolic process GO:0045934 261 0.219
Mouse
protein modification process GO:0036211 438 0.201
growth GO:0040007 359 0.172
Mouse
autophagy GO:0006914 108 0.169
negative regulation of cellular metabolic process GO:0031324 382 0.157
Mouse
regulation of cell development GO:0060284 215 0.148
negative regulation of cell communication GO:0010648 223 0.136
Human
embryonic morphogenesis GO:0048598 206 0.132
Zebrafish Mouse
morphogenesis of an epithelium GO:0002009 276 0.129
organic acid metabolic process GO:0006082 103 0.115
meiotic cell cycle GO:0051321 171 0.115
catabolic process GO:0009056 409 0.106
positive regulation of biosynthetic process GO:0009891 316 0.103
Human Mouse
death GO:0016265 284 0.101
adult behavior GO:0030534 137 0.101
regulation of nervous system development GO:0051960 248 0.100
single organism behavior GO:0044708 391 0.097
imaginal disc derived appendage morphogenesis GO:0035114 395 0.095
negative regulation of response to stimulus GO:0048585 258 0.093
Human
positive regulation of cellular biosynthetic process GO:0031328 316 0.091
Human Mouse
programmed cell death GO:0012501 257 0.089
cellular protein modification process GO:0006464 438 0.088
organonitrogen compound metabolic process GO:1901564 318 0.087
digestive tract development GO:0048565 149 0.083
Zebrafish
eye development GO:0001654 323 0.081
negative regulation of rna metabolic process GO:0051253 251 0.081
Mouse
locomotory behavior GO:0007626 176 0.079
regulation of growth GO:0040008 233 0.079
small molecule metabolic process GO:0044281 305 0.077
organic substance transport GO:0071702 257 0.076
negative regulation of macromolecule biosynthetic process GO:0010558 270 0.075
Mouse
tube morphogenesis GO:0035239 191 0.075
Zebrafish
adult locomotory behavior GO:0008344 76 0.074
post embryonic appendage morphogenesis GO:0035120 385 0.073
tube development GO:0035295 244 0.073
Zebrafish
single organism intracellular transport GO:1902582 207 0.073
vesicle mediated transport GO:0016192 381 0.073
establishment of localization in cell GO:0051649 402 0.069
meiotic cell cycle process GO:1903046 132 0.069
single organism catabolic process GO:0044712 228 0.067
synaptic transmission GO:0007268 288 0.066
carbohydrate derivative metabolic process GO:1901135 217 0.066
positive regulation of macromolecule biosynthetic process GO:0010557 283 0.066
Human Mouse
imaginal disc derived appendage development GO:0048737 399 0.066
axonogenesis GO:0007409 290 0.066
digestive tract morphogenesis GO:0048546 127 0.063
Zebrafish
regulation of catalytic activity GO:0050790 185 0.062
Human
purine ribonucleoside metabolic process GO:0046128 127 0.062
cellular catabolic process GO:0044248 372 0.059
appendage development GO:0048736 401 0.058
developmental programmed cell death GO:0010623 138 0.058
ribose phosphate metabolic process GO:0019693 145 0.057
glycosyl compound metabolic process GO:1901657 127 0.057
negative regulation of transcription from rna polymerase ii promoter GO:0000122 119 0.057
Mouse
cellular amino acid metabolic process GO:0006520 61 0.056
negative regulation of nitrogen compound metabolic process GO:0051172 265 0.056
Mouse
regulation of cell cycle GO:0051726 291 0.055
enzyme linked receptor protein signaling pathway GO:0007167 179 0.054
positive regulation of macromolecule metabolic process GO:0010604 405 0.054
Human Mouse
cell death GO:0008219 279 0.054
negative regulation of biosynthetic process GO:0009890 277 0.053
Mouse
positive regulation of multicellular organismal process GO:0051240 143 0.053
organophosphate metabolic process GO:0019637 195 0.052
oxoacid metabolic process GO:0043436 103 0.052
regulation of multicellular organismal development GO:2000026 414 0.052
negative regulation of nucleic acid templated transcription GO:1903507 240 0.052
Mouse
developmental maturation GO:0021700 172 0.051
nucleoside phosphate metabolic process GO:0006753 162 0.051
single organism cellular localization GO:1902580 180 0.049
taxis GO:0042330 304 0.048
organic cyclic compound catabolic process GO:1901361 168 0.048
purine nucleotide catabolic process GO:0006195 109 0.048
digestive system development GO:0055123 149 0.048
Zebrafish
carboxylic acid metabolic process GO:0019752 92 0.048
positive regulation of transcription from rna polymerase ii promoter GO:0045944 204 0.047
Human Mouse
cell maturation GO:0048469 144 0.047
positive regulation of developmental process GO:0051094 143 0.046
purine ribonucleotide metabolic process GO:0009150 145 0.045
regulation of developmental growth GO:0048638 174 0.045
meiotic nuclear division GO:0007126 151 0.044
forebrain development GO:0030900 2 0.044
intracellular transport GO:0046907 228 0.043
imaginal disc derived leg morphogenesis GO:0007480 80 0.043
aromatic compound catabolic process GO:0019439 166 0.043
regulation of molecular function GO:0065009 217 0.043
Human
single organism biosynthetic process GO:0044711 206 0.043
regulation of localization GO:0032879 275 0.042
positive regulation of nucleic acid templated transcription GO:1903508 266 0.042
Human Mouse
exocrine system development GO:0035272 162 0.042
purine containing compound metabolic process GO:0072521 155 0.040
response to oxidative stress GO:0006979 86 0.040
leg disc development GO:0035218 92 0.039
protein modification by small protein conjugation or removal GO:0070647 106 0.039
nucleotide metabolic process GO:0009117 161 0.039
regulation of autophagy GO:0010506 62 0.038
cellular homeostasis GO:0019725 80 0.038
immune system process GO:0002376 347 0.038
purine nucleoside metabolic process GO:0042278 127 0.038
positive regulation of nucleobase containing compound metabolic process GO:0045935 332 0.037
Human Mouse
gland development GO:0048732 191 0.037
nucleotide catabolic process GO:0009166 109 0.037
positive regulation of catabolic process GO:0009896 105 0.036
tissue morphogenesis GO:0048729 297 0.036
regulation of apoptotic process GO:0042981 130 0.036
negative regulation of developmental process GO:0051093 201 0.035
Mouse
nuclear division GO:0000280 332 0.035
negative regulation of transcription dna templated GO:0045892 237 0.035
Mouse
ribonucleotide metabolic process GO:0009259 145 0.035
negative regulation of gene expression GO:0010629 387 0.034
Human Mouse
leg disc morphogenesis GO:0007478 80 0.034
organelle assembly GO:0070925 198 0.034
homeostatic process GO:0042592 199 0.033
organelle fission GO:0048285 340 0.033
neurological system process GO:0050877 358 0.033
purine ribonucleoside triphosphate metabolic process GO:0009205 119 0.032
immune system development GO:0002520 57 0.032
tissue death GO:0016271 102 0.032
purine nucleoside triphosphate metabolic process GO:0009144 119 0.032
cellular response to extracellular stimulus GO:0031668 64 0.032
negative regulation of rna biosynthetic process GO:1902679 240 0.032
Mouse
positive regulation of nitrogen compound metabolic process GO:0051173 354 0.032
Human Mouse
alpha amino acid metabolic process GO:1901605 20 0.032
response to endogenous stimulus GO:0009719 119 0.031
Human Zebrafish
positive regulation of transcription dna templated GO:0045893 266 0.031
Human Mouse
chemotaxis GO:0006935 249 0.031
regulation of protein import into nucleus GO:0042306 28 0.031
regulation of cellular catabolic process GO:0031329 157 0.031
compound eye development GO:0048749 307 0.031
protein modification by small protein conjugation GO:0032446 79 0.030
multicellular organism growth GO:0035264 46 0.030
cellular response to organic substance GO:0071310 132 0.030
Human Zebrafish
hemopoiesis GO:0030097 46 0.030
muscle structure development GO:0061061 224 0.030
ribonucleoside metabolic process GO:0009119 127 0.030
nucleobase containing compound catabolic process GO:0034655 165 0.030
cellular nitrogen compound catabolic process GO:0044270 165 0.030
cell growth GO:0016049 108 0.029
salivary gland development GO:0007431 162 0.029
protein transport GO:0015031 155 0.029
camera type eye development GO:0043010 4 0.029
response to reactive oxygen species GO:0000302 24 0.029
regulation of neurogenesis GO:0050767 158 0.029
regulation of cellular localization GO:0060341 136 0.029
ribonucleoside triphosphate metabolic process GO:0009199 119 0.029
intracellular signal transduction GO:0035556 300 0.028
Human
apoptotic process GO:0006915 159 0.028
epithelial tube morphogenesis GO:0060562 88 0.028
regulation of response to stress GO:0080134 200 0.028
regulation of programmed cell death GO:0043067 152 0.027
regulation of cellular component size GO:0032535 98 0.027
purine ribonucleotide catabolic process GO:0009154 109 0.027
nucleobase containing small molecule metabolic process GO:0055086 174 0.027
regulation of cell differentiation GO:0045595 302 0.027
Mouse
positive regulation of signaling GO:0023056 243 0.026
Human
mesenchymal cell differentiation GO:0048762 1 0.026
appendage morphogenesis GO:0035107 397 0.026
response to nitrogen compound GO:1901698 90 0.026
gland morphogenesis GO:0022612 145 0.026
axon development GO:0061564 297 0.026
negative regulation of cellular macromolecule biosynthetic process GO:2000113 267 0.026
Mouse
ribonucleoside catabolic process GO:0042454 112 0.026
regulation of transcription from rna polymerase ii promoter GO:0006357 378 0.025
Human Zebrafish Mouse
guanosine containing compound catabolic process GO:1901069 74 0.025
axon guidance GO:0007411 233 0.025
body morphogenesis GO:0010171 2 0.024
cell motility GO:0048870 251 0.024
Zebrafish
regulation of phosphorus metabolic process GO:0051174 210 0.024
imaginal disc derived wing morphogenesis GO:0007476 337 0.024
positive regulation of cell motility GO:2000147 3 0.024
positive regulation of rna biosynthetic process GO:1902680 266 0.024
Human Mouse
negative regulation of signaling GO:0023057 219 0.024
Human
organic substance catabolic process GO:1901575 308 0.024
endocytosis GO:0006897 310 0.024
positive regulation of cell migration GO:0030335 2 0.023
defense response GO:0006952 300 0.023
positive regulation of cell development GO:0010720 61 0.023
brain development GO:0007420 120 0.023
response to lipopolysaccharide GO:0032496 4 0.023
glycoprotein metabolic process GO:0009100 41 0.023
pigmentation GO:0043473 75 0.023
salivary gland morphogenesis GO:0007435 145 0.023
response to abiotic stimulus GO:0009628 341 0.023
transmembrane receptor protein tyrosine kinase signaling pathway GO:0007169 116 0.023
compound eye morphogenesis GO:0001745 249 0.022
regulation of catabolic process GO:0009894 170 0.022
response to toxic substance GO:0009636 22 0.022
heterocycle catabolic process GO:0046700 166 0.022
cellular metal ion homeostasis GO:0006875 31 0.022
cellular amine metabolic process GO:0044106 12 0.022
regulation of cell size GO:0008361 63 0.022
amine metabolic process GO:0009308 12 0.021
response to wounding GO:0009611 94 0.021
cyclic nucleotide metabolic process GO:0009187 28 0.021
nucleoside triphosphate catabolic process GO:0009143 108 0.021
neural precursor cell proliferation GO:0061351 75 0.021
cognition GO:0050890 141 0.021
cellular response to chemical stimulus GO:0070887 199 0.021
Human Zebrafish
molting cycle chitin based cuticle GO:0007591 56 0.021
protein localization to organelle GO:0033365 82 0.021
purine containing compound catabolic process GO:0072523 112 0.020
organophosphate biosynthetic process GO:0090407 46 0.020
response to hexose GO:0009746 3 0.020
regulation of cell death GO:0010941 173 0.020
purine ribonucleotide biosynthetic process GO:0009152 28 0.020
purine ribonucleoside catabolic process GO:0046130 112 0.020
positive regulation of rna metabolic process GO:0051254 271 0.020
Human Mouse
regulation of multicellular organism growth GO:0040014 40 0.020
cell proliferation GO:0008283 299 0.019
Mouse
regulation of protein metabolic process GO:0051246 256 0.019
gastrulation GO:0007369 70 0.019
Zebrafish
developmental growth GO:0048589 280 0.019
Mouse
response to organic cyclic compound GO:0014070 89 0.019
Human Zebrafish
carbohydrate derivative biosynthetic process GO:1901137 85 0.019
protein targeting GO:0006605 64 0.019
gliogenesis GO:0042063 80 0.019
cellular response to hexose stimulus GO:0071331 1 0.019
establishment of protein localization GO:0045184 163 0.018
regulation of cellular amine metabolic process GO:0033238 3 0.018
glycosyl compound catabolic process GO:1901658 112 0.018
autophagic cell death GO:0048102 83 0.018
cellular response to molecule of bacterial origin GO:0071219 3 0.018
phagocytosis GO:0006909 215 0.018
mesenchymal cell development GO:0014031 1 0.018
positive regulation of programmed cell death GO:0043068 62 0.018
purine nucleoside catabolic process GO:0006152 112 0.018
response to metal ion GO:0010038 23 0.018
connective tissue development GO:0061448 3 0.018
cellular response to lipopolysaccharide GO:0071222 3 0.018
nucleoside metabolic process GO:0009116 127 0.018
central nervous system development GO:0007417 201 0.018
anatomical structure homeostasis GO:0060249 97 0.017
positive regulation of gene expression GO:0010628 290 0.017
Human Mouse
protein targeting to nucleus GO:0044744 51 0.017
response to starvation GO:0042594 97 0.017
cholesterol homeostasis GO:0042632 3 0.017
cellular macromolecule localization GO:0070727 220 0.017
telencephalon development GO:0021537 2 0.017
positive regulation of transport GO:0051050 92 0.017
regulation of ras protein signal transduction GO:0046578 93 0.017
chromatin modification GO:0016568 147 0.017
positive regulation of cellular catabolic process GO:0031331 95 0.017
carbohydrate derivative catabolic process GO:1901136 118 0.017
chromosome organization GO:0051276 360 0.016
rho protein signal transduction GO:0007266 14 0.016
response to light stimulus GO:0009416 124 0.016
regulation of transport GO:0051049 181 0.016
positive regulation of protein metabolic process GO:0051247 128 0.016
organelle localization GO:0051640 148 0.016
positive regulation of cellular protein metabolic process GO:0032270 118 0.016
negative regulation of phosphorus metabolic process GO:0010563 45 0.016
wound healing GO:0042060 75 0.016
cytoplasmic transport GO:0016482 130 0.016
response to glucose GO:0009749 2 0.016
regulation of intracellular signal transduction GO:1902531 236 0.016
Human
ribonucleotide catabolic process GO:0009261 109 0.016
regulation of cell cycle process GO:0010564 181 0.016
positive regulation of ras gtpase activity GO:0032320 36 0.015
neuroblast proliferation GO:0007405 74 0.015
response to inorganic substance GO:0010035 44 0.015
ribonucleoside triphosphate catabolic process GO:0009203 108 0.015
positive regulation of growth GO:0045927 75 0.015
larval development GO:0002164 104 0.015
positive regulation of cell differentiation GO:0045597 64 0.015
secretion by cell GO:0032940 101 0.015
response to nutrient levels GO:0031667 114 0.015
sensory organ morphogenesis GO:0090596 260 0.015
Zebrafish
chromosome segregation GO:0007059 157 0.015
hematopoietic or lymphoid organ development GO:0048534 57 0.015
regulation of phosphate metabolic process GO:0019220 210 0.015
purine ribonucleoside triphosphate catabolic process GO:0009207 108 0.014
cellular response to dna damage stimulus GO:0006974 223 0.014
cyclic nucleotide biosynthetic process GO:0009190 25 0.014
nitrogen compound transport GO:0071705 85 0.014
photoreceptor cell differentiation GO:0046530 170 0.014
regulation of protein localization GO:0032880 76 0.014
response to organic substance GO:0010033 284 0.014
Human Zebrafish
oocyte development GO:0048599 124 0.014
epithelial cell differentiation GO:0030855 322 0.014
sulfur compound biosynthetic process GO:0044272 16 0.014
positive regulation of immune system process GO:0002684 68 0.014
cellular response to carbohydrate stimulus GO:0071322 4 0.014
sterol homeostasis GO:0055092 4 0.014
retina development in camera type eye GO:0060041 4 0.014
response to monosaccharide GO:0034284 4 0.014
cellular response to endogenous stimulus GO:0071495 80 0.014
Human Zebrafish
regulation of small gtpase mediated signal transduction GO:0051056 93 0.014
nucleocytoplasmic transport GO:0006913 72 0.014
ras protein signal transduction GO:0007265 88 0.014
posttranscriptional regulation of gene expression GO:0010608 145 0.014
cellular macromolecule catabolic process GO:0044265 136 0.014
secretion GO:0046903 109 0.014
nuclear import GO:0051170 51 0.014
embryo development ending in birth or egg hatching GO:0009792 152 0.014
Mouse
organonitrogen compound biosynthetic process GO:1901566 117 0.014
meiosis i GO:0007127 59 0.014
histolysis GO:0007559 102 0.013
establishment of organelle localization GO:0051656 122 0.013
lipid metabolic process GO:0006629 121 0.013
notch signaling pathway GO:0007219 120 0.013
signal release GO:0023061 49 0.013
purine containing compound biosynthetic process GO:0072522 30 0.013
regulation of immune system process GO:0002682 176 0.013
macromolecule catabolic process GO:0009057 161 0.013
nuclear transport GO:0051169 72 0.013
regulation of cellular response to stress GO:0080135 89 0.013
regulation of nucleotide metabolic process GO:0006140 62 0.013
determination of adult lifespan GO:0008340 137 0.013
regulation of transmembrane receptor protein serine threonine kinase signaling pathway GO:0090092 38 0.013
cellular response to growth factor stimulus GO:0071363 30 0.013
nucleoside catabolic process GO:0009164 112 0.013
regulation of cellular component movement GO:0051270 42 0.012
positive regulation of response to stimulus GO:0048584 323 0.012
Human
negative regulation of sequence specific dna binding transcription factor activity GO:0043433 4 0.012
Human
spermatogenesis GO:0007283 200 0.012
protein import into nucleus GO:0006606 51 0.012
regulation of anatomical structure morphogenesis GO:0022603 242 0.012
cell cycle checkpoint GO:0000075 95 0.012
regulation of synaptic transmission GO:0050804 69 0.012
cellular response to external stimulus GO:0071496 66 0.012
gtp metabolic process GO:0046039 72 0.012
stem cell proliferation GO:0072089 88 0.012
transmembrane receptor protein serine threonine kinase signaling pathway GO:0007178 65 0.012
regulation of cellular protein metabolic process GO:0032268 243 0.012
transcription from rna polymerase ii promoter GO:0006366 368 0.012
Human Zebrafish Mouse
hindbrain development GO:0030902 2 0.012
regulation of establishment of protein localization GO:0070201 61 0.012
cellular pigmentation GO:0033059 12 0.012
salivary gland cell autophagic cell death GO:0035071 83 0.012
regionalization GO:0003002 416 0.012
negative regulation of cell death GO:0060548 81 0.012
purine nucleotide metabolic process GO:0006163 146 0.012
regulation of cytoplasmic transport GO:1903649 47 0.012
salivary gland histolysis GO:0035070 88 0.012
chromatin organization GO:0006325 207 0.012
wing disc morphogenesis GO:0007472 344 0.012
small gtpase mediated signal transduction GO:0007264 88 0.012
cellular lipid metabolic process GO:0044255 83 0.012
cellular response to insulin stimulus GO:0032869 28 0.012
macroautophagy GO:0016236 42 0.012
regulation of purine nucleotide metabolic process GO:1900542 62 0.011
anion homeostasis GO:0055081 3 0.011
sulfur compound metabolic process GO:0006790 59 0.011
cellular protein localization GO:0034613 160 0.011
positive regulation of cell communication GO:0010647 250 0.011
Human
response to oxygen containing compound GO:1901700 200 0.011
Human Zebrafish
negative regulation of catalytic activity GO:0043086 42 0.011
olfactory behavior GO:0042048 97 0.011
cellular response to starvation GO:0009267 61 0.011
cell fate determination GO:0001709 91 0.011
protein localization GO:0008104 284 0.011
purine nucleotide biosynthetic process GO:0006164 29 0.011
cyclic purine nucleotide metabolic process GO:0052652 25 0.011
positive regulation of cell death GO:0010942 69 0.011
regulation of secretion by cell GO:1903530 39 0.011
organonitrogen compound catabolic process GO:1901565 128 0.011
golgi organization GO:0007030 66 0.011
regulation of peptide secretion GO:0002791 6 0.011
regulation of cellular ketone metabolic process GO:0010565 3 0.011
regulation of cellular amino acid metabolic process GO:0006521 0 0.011
mitochondrion organization GO:0007005 65 0.011
nucleoside triphosphate metabolic process GO:0009141 120 0.011
establishment of protein localization to organelle GO:0072594 62 0.010
positive regulation of catalytic activity GO:0043085 118 0.010
Human
positive regulation of developmental growth GO:0048639 62 0.010
microtubule based movement GO:0007018 51 0.010
response to hypoxia GO:0001666 53 0.010
positive regulation of cell size GO:0045793 21 0.010
protein import GO:0017038 55 0.010
learning or memory GO:0007611 141 0.010
regulation of cell shape GO:0008360 113 0.010
response to organonitrogen compound GO:0010243 75 0.010
memory GO:0007613 94 0.010
negative regulation of apoptotic process GO:0043066 63 0.010
regulation of protein transport GO:0051223 57 0.010
mitotic sister chromatid segregation GO:0000070 87 0.010
proteolysis GO:0006508 192 0.010

ERR disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in fly and predicted with the fly functional network.

Disease DO term ID Size Probability Func Analog Org
disease of metabolism DOID:0014667 0 0.027
disease of anatomical entity DOID:7 0 0.010
Human