Drosophila melanogaster

0 known processes

Mhcl (Dmel_CG31045)

Myosin heavy chain-like

(Aliases: MHCL(PDZ),DmPDZ,CG10224,Dmel\CG31045,CG31045,CG10218)

Mhcl biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
morphogenesis of an epithelium GO:0002009 276 0.118
cellular protein modification process GO:0006464 438 0.109
negative regulation of response to stimulus GO:0048585 258 0.090
protein modification process GO:0036211 438 0.081
columnar cuboidal epithelial cell development GO:0002066 249 0.077
regulation of protein metabolic process GO:0051246 256 0.075
tissue morphogenesis GO:0048729 297 0.073
regulation of cellular protein metabolic process GO:0032268 243 0.073
single organism behavior GO:0044708 391 0.071
regulation of localization GO:0032879 275 0.065
Human
phosphorylation GO:0016310 294 0.064
negative regulation of signaling GO:0023057 219 0.063
chromosome organization GO:0051276 360 0.063
negative regulation of signal transduction GO:0009968 206 0.061
negative regulation of cell communication GO:0010648 223 0.058
cation transport GO:0006812 110 0.057
columnar cuboidal epithelial cell differentiation GO:0002065 256 0.051
nuclear division GO:0000280 332 0.049
intracellular signal transduction GO:0035556 300 0.048
cellular macromolecule localization GO:0070727 220 0.047
protein complex assembly GO:0006461 200 0.046
regulation of phosphorus metabolic process GO:0051174 210 0.045
positive regulation of signaling GO:0023056 243 0.045
regulation of cellular component biogenesis GO:0044087 201 0.045
small molecule metabolic process GO:0044281 305 0.043
organelle fission GO:0048285 340 0.043
axon development GO:0061564 297 0.042
regulation of transport GO:0051049 181 0.041
Human
vesicle mediated transport GO:0016192 381 0.041
Human
cell migration GO:0016477 238 0.038
Human
epithelial cell differentiation GO:0030855 322 0.038
protein localization GO:0008104 284 0.037
Human
response to abiotic stimulus GO:0009628 341 0.037
regulation of molecular function GO:0065009 217 0.034
cell cell junction organization GO:0045216 55 0.034
regulation of intracellular signal transduction GO:1902531 236 0.034
positive regulation of cell communication GO:0010647 250 0.034
protein complex biogenesis GO:0070271 201 0.034
cell junction organization GO:0034330 57 0.033
regulation of response to stress GO:0080134 200 0.033
cellular component assembly involved in morphogenesis GO:0010927 151 0.032
positive regulation of transport GO:0051050 92 0.032
Human
ion transport GO:0006811 145 0.031
regionalization GO:0003002 416 0.031
mitotic nuclear division GO:0007067 213 0.030
catabolic process GO:0009056 409 0.029
organelle assembly GO:0070925 198 0.029
regulation of catalytic activity GO:0050790 185 0.028
regulation of cellular amine metabolic process GO:0033238 3 0.028
protein phosphorylation GO:0006468 169 0.027
single organism intracellular transport GO:1902582 207 0.027
Human
homeostatic process GO:0042592 199 0.027
macromolecular complex assembly GO:0065003 256 0.027
signal transduction by phosphorylation GO:0023014 107 0.025
intracellular transport GO:0046907 228 0.025
Human
macromolecule catabolic process GO:0009057 161 0.024
proteolysis GO:0006508 192 0.024
positive regulation of macromolecule metabolic process GO:0010604 405 0.024
positive regulation of cellular component biogenesis GO:0044089 80 0.024
cytoplasmic transport GO:0016482 130 0.024
positive regulation of signal transduction GO:0009967 223 0.024
metal ion transport GO:0030001 74 0.023
protein transport GO:0015031 155 0.023
Human
regulation of organelle organization GO:0033043 196 0.023
enzyme linked receptor protein signaling pathway GO:0007167 179 0.023
cellular ketone metabolic process GO:0042180 24 0.023
regulation of cell differentiation GO:0045595 302 0.022
organonitrogen compound metabolic process GO:1901564 318 0.022
aging GO:0007568 143 0.022
appendage development GO:0048736 401 0.022
endomembrane system organization GO:0010256 119 0.022
Human
carboxylic acid metabolic process GO:0019752 92 0.022
establishment of localization in cell GO:0051649 402 0.022
Human
regulation of phosphorylation GO:0042325 147 0.022
epidermis development GO:0008544 65 0.021
actin cytoskeleton organization GO:0030036 206 0.021
Human
regulation of mapk cascade GO:0043408 92 0.021
regulation of transferase activity GO:0051338 58 0.021
cellular homeostasis GO:0019725 80 0.021
eye development GO:0001654 323 0.021
regulation of phosphate metabolic process GO:0019220 210 0.021
single organism membrane organization GO:0044802 93 0.021
Human
oxoacid metabolic process GO:0043436 103 0.021
locomotory behavior GO:0007626 176 0.021
endocytosis GO:0006897 310 0.021
regulation of protein modification process GO:0031399 112 0.021
axonogenesis GO:0007409 290 0.020
memory GO:0007613 94 0.020
gliogenesis GO:0042063 80 0.020
establishment of protein localization GO:0045184 163 0.020
Human
spindle organization GO:0007051 253 0.020
embryo development ending in birth or egg hatching GO:0009792 152 0.020
embryonic development via the syncytial blastoderm GO:0001700 148 0.020
chemotaxis GO:0006935 249 0.019
embryonic morphogenesis GO:0048598 206 0.019
cell projection assembly GO:0030031 94 0.019
anatomical structure homeostasis GO:0060249 97 0.019
larval development GO:0002164 104 0.019
chromatin organization GO:0006325 207 0.019
cell motility GO:0048870 251 0.019
Human
ameboidal type cell migration GO:0001667 151 0.019
ovarian follicle cell development GO:0030707 248 0.019
rna localization GO:0006403 115 0.019
establishment or maintenance of cell polarity GO:0007163 167 0.019
positive regulation of nitrogen compound metabolic process GO:0051173 354 0.018
regulation of immune system process GO:0002682 176 0.018
regulation of cellular catabolic process GO:0031329 157 0.018
epithelial cell development GO:0002064 274 0.018
organic substance transport GO:0071702 257 0.018
Human
tube development GO:0035295 244 0.018
chromosome segregation GO:0007059 157 0.018
cellular amino acid metabolic process GO:0006520 61 0.018
mapk cascade GO:0000165 107 0.018
developmental growth GO:0048589 280 0.018
cellular macromolecule catabolic process GO:0044265 136 0.018
sister chromatid segregation GO:0000819 92 0.018
positive regulation of response to stimulus GO:0048584 323 0.018
organic substance catabolic process GO:1901575 308 0.017
positive regulation of cellular component organization GO:0051130 156 0.017
synaptic transmission GO:0007268 288 0.017
multicellular organismal aging GO:0010259 140 0.017
positive regulation of protein metabolic process GO:0051247 128 0.017
cellular catabolic process GO:0044248 372 0.017
chemical homeostasis GO:0048878 92 0.017
regulation of immune response GO:0050776 118 0.017
regulation of protein phosphorylation GO:0001932 64 0.017
biological adhesion GO:0022610 138 0.017
cellular protein complex assembly GO:0043623 71 0.017
cellular response to chemical stimulus GO:0070887 199 0.017
wound healing GO:0042060 75 0.017
negative regulation of intracellular signal transduction GO:1902532 57 0.016
actin filament organization GO:0007015 126 0.016
ovarian follicle cell migration GO:0007297 121 0.016
organophosphate metabolic process GO:0019637 195 0.016
taxis GO:0042330 304 0.016
immune response regulating signaling pathway GO:0002764 2 0.016
cell proliferation GO:0008283 299 0.016
cell maturation GO:0048469 144 0.016
open tracheal system development GO:0007424 204 0.016
growth GO:0040007 359 0.016
regulation of gene expression epigenetic GO:0040029 128 0.016
compound eye development GO:0048749 307 0.015
hair cell differentiation GO:0035315 47 0.015
positive regulation of cellular protein metabolic process GO:0032270 118 0.015
compound eye photoreceptor development GO:0042051 78 0.015
epidermal cell differentiation GO:0009913 51 0.015
regulation of mrna processing GO:0050684 71 0.015
covalent chromatin modification GO:0016569 106 0.015
organic acid metabolic process GO:0006082 103 0.015
immune system process GO:0002376 347 0.015
mrna processing GO:0006397 104 0.015
hematopoietic progenitor cell differentiation GO:0002244 1 0.015
positive regulation of phosphate metabolic process GO:0045937 139 0.015
developmental maturation GO:0021700 172 0.015
morphogenesis of embryonic epithelium GO:0016331 94 0.015
regulation of cellular localization GO:0060341 136 0.015
Human
positive regulation of cellular biosynthetic process GO:0031328 316 0.015
cellular protein catabolic process GO:0044257 83 0.014
regulation of cell proliferation GO:0042127 163 0.014
negative regulation of cellular metabolic process GO:0031324 382 0.014
mrna metabolic process GO:0016071 124 0.014
regulation of cellular amino acid metabolic process GO:0006521 0 0.014
regulation of transcription from rna polymerase ii promoter GO:0006357 378 0.014
positive regulation of immune system process GO:0002684 68 0.014
modification dependent protein catabolic process GO:0019941 78 0.014
positive regulation of nucleobase containing compound metabolic process GO:0045935 332 0.014
negative regulation of phosphorylation GO:0042326 35 0.014
intracellular protein transport GO:0006886 104 0.014
regulation of cellular ketone metabolic process GO:0010565 3 0.014
wnt signaling pathway GO:0016055 98 0.014
positive regulation of molecular function GO:0044093 136 0.014
ion transmembrane transport GO:0034220 122 0.014
cellular amine metabolic process GO:0044106 12 0.014
epithelial cell migration GO:0010631 148 0.014
defense response GO:0006952 300 0.014
negative regulation of cellular protein metabolic process GO:0032269 85 0.013
photoreceptor cell development GO:0042461 96 0.013
positive regulation of intracellular signal transduction GO:1902533 116 0.013
mitotic spindle organization GO:0007052 220 0.013
single organism biosynthetic process GO:0044711 206 0.013
positive regulation of phosphorus metabolic process GO:0010562 139 0.013
negative regulation of molecular function GO:0044092 51 0.013
negative regulation of phosphorus metabolic process GO:0010563 45 0.013
carbohydrate derivative metabolic process GO:1901135 217 0.013
actin filament based process GO:0030029 220 0.013
Human
meiotic cell cycle GO:0051321 171 0.013
response to lipopolysaccharide GO:0032496 4 0.013
positive regulation of cell motility GO:2000147 3 0.012
response to organonitrogen compound GO:0010243 75 0.012
kidney development GO:0001822 3 0.012
regulation of multicellular organismal development GO:2000026 414 0.012
protein catabolic process GO:0030163 101 0.012
posttranscriptional regulation of gene expression GO:0010608 145 0.012
neurological system process GO:0050877 358 0.012
cell division GO:0051301 248 0.012
epidermal growth factor receptor signaling pathway GO:0007173 58 0.012
negative regulation of protein metabolic process GO:0051248 85 0.012
histone modification GO:0016570 106 0.012
dephosphorylation GO:0016311 51 0.012
negative regulation of developmental process GO:0051093 201 0.012
negative regulation of gene expression GO:0010629 387 0.012
positive regulation of organelle organization GO:0010638 65 0.012
neuron projection guidance GO:0097485 241 0.012
imaginal disc derived appendage morphogenesis GO:0035114 395 0.012
nucleoside phosphate metabolic process GO:0006753 162 0.012
monovalent inorganic cation transport GO:0015672 40 0.012
axis specification GO:0009798 167 0.012
compound eye photoreceptor cell differentiation GO:0001751 140 0.012
negative regulation of phosphate metabolic process GO:0045936 45 0.012
camera type eye development GO:0043010 4 0.012
axon guidance GO:0007411 233 0.011
mitotic sister chromatid segregation GO:0000070 87 0.011
dendrite development GO:0016358 204 0.011
regulation of transmembrane transport GO:0034762 27 0.011
cellular protein localization GO:0034613 160 0.011
adult locomotory behavior GO:0008344 76 0.011
regulation of kinase activity GO:0043549 53 0.011
regulation of chromosome organization GO:0033044 64 0.011
central nervous system development GO:0007417 201 0.011
positive regulation of transcription from rna polymerase ii promoter GO:0045944 204 0.011
transmembrane transport GO:0055085 139 0.011
response to organic substance GO:0010033 284 0.011
oxidation reduction process GO:0055114 123 0.011
positive regulation of catalytic activity GO:0043085 118 0.011
g protein coupled receptor signaling pathway GO:0007186 136 0.011
chromatin modification GO:0016568 147 0.011
protein modification by small protein conjugation or removal GO:0070647 106 0.011
response to endogenous stimulus GO:0009719 119 0.011
regulation of erbb signaling pathway GO:1901184 42 0.011
immune response GO:0006955 246 0.011
single organism cellular localization GO:1902580 180 0.011
Human
phagocytosis GO:0006909 215 0.011
positive regulation of cell migration GO:0030335 2 0.011
apoptotic process GO:0006915 159 0.010
eye photoreceptor cell differentiation GO:0001754 145 0.010
ubiquitin dependent protein catabolic process GO:0006511 78 0.010
muscle structure development GO:0061061 224 0.010
nucleobase containing small molecule metabolic process GO:0055086 174 0.010
response to organophosphorus GO:0046683 2 0.010
cardiovascular system development GO:0072358 82 0.010
localization of cell GO:0051674 257 0.010
Human
cellular response to organic substance GO:0071310 132 0.010
regulation of lipid transport GO:0032368 3 0.010
regulation of ion transport GO:0043269 39 0.010
circulatory system development GO:0072359 82 0.010
response to wounding GO:0009611 94 0.010
cell cell junction assembly GO:0007043 38 0.010
regulation of defense response GO:0031347 102 0.010
proteolysis involved in cellular protein catabolic process GO:0051603 83 0.010
modification dependent macromolecule catabolic process GO:0043632 79 0.010

Mhcl disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in fly and predicted with the fly functional network.

Disease DO term ID Size Probability Func Analog Org
disease of anatomical entity DOID:7 0 0.036
cardiovascular system disease DOID:1287 0 0.017
urinary system disease DOID:18 0 0.011
nervous system disease DOID:863 0 0.010