Drosophila melanogaster

123 known processes

fz2 (Dmel_CG9739)

frizzled 2

(Aliases: fz-2,Dfz[[2]],dfz2,Dmel\CG9739,D-Fz2,FZ2,Dfrz2,dfz2r,D-fz2,Dfz2,CG9739,dFz2,Fz2,frz2,DFz-2,DFZ2,DFz2,dfz(2))

fz2 biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
imaginal disc derived appendage morphogenesis GO:0035114 395 0.997
morphogenesis of an epithelium GO:0002009 276 0.996
Mouse Fly
tissue morphogenesis GO:0048729 297 0.993
Mouse Fly
post embryonic appendage morphogenesis GO:0035120 385 0.991
appendage morphogenesis GO:0035107 397 0.991
synapse organization GO:0050808 196 0.991
tube morphogenesis GO:0035239 191 0.990
imaginal disc derived wing margin morphogenesis GO:0008587 41 0.987
wing disc morphogenesis GO:0007472 344 0.978
appendage development GO:0048736 401 0.973
dorsal ventral pattern formation GO:0009953 133 0.973
Human Zebrafish
imaginal disc derived appendage development GO:0048737 399 0.971
tube development GO:0035295 244 0.964
digestive tract morphogenesis GO:0048546 127 0.956
digestive system development GO:0055123 149 0.955
imaginal disc derived wing morphogenesis GO:0007476 337 0.947
embryonic morphogenesis GO:0048598 206 0.942
Zebrafish Mouse
signal release GO:0023061 49 0.934
synapse assembly GO:0007416 143 0.919
regulation of synapse structure and activity GO:0050803 128 0.915
dendrite morphogenesis GO:0048813 199 0.914
wnt signaling pathway GO:0016055 98 0.907
gastrulation GO:0007369 70 0.903
growth GO:0040007 359 0.896
regulation of localization GO:0032879 275 0.896
gland morphogenesis GO:0022612 145 0.887
regulation of multicellular organismal development GO:2000026 414 0.882
cell junction assembly GO:0034329 42 0.876
Mouse
neuroblast proliferation GO:0007405 74 0.862
neuromuscular junction development GO:0007528 149 0.858
salivary gland development GO:0007431 162 0.856
imaginal disc derived wing hair organization GO:0035317 45 0.841
Fly
eye development GO:0001654 323 0.840
Zebrafish Mouse Fly
eye photoreceptor cell fate commitment GO:0042706 37 0.835
Fly
dendrite development GO:0016358 204 0.824
developmental growth involved in morphogenesis GO:0060560 65 0.801
salivary gland morphogenesis GO:0007435 145 0.796
cell motility GO:0048870 251 0.790
sensory organ morphogenesis GO:0090596 260 0.781
Zebrafish Fly
embryonic development via the syncytial blastoderm GO:0001700 148 0.780
neurotransmitter transport GO:0006836 37 0.779
regulation of anatomical structure size GO:0090066 163 0.777
Fly
establishment or maintenance of cell polarity GO:0007163 167 0.772
Fly
establishment of localization in cell GO:0051649 402 0.770
cell migration GO:0016477 238 0.756
regulation of cell morphogenesis GO:0022604 163 0.753
axon development GO:0061564 297 0.738
establishment of imaginal disc derived wing hair orientation GO:0001737 24 0.732
Fly
dorsal closure GO:0007391 79 0.697
non canonical wnt signaling pathway GO:0035567 8 0.696
Zebrafish
regulation of cell differentiation GO:0045595 302 0.690
neuron recognition GO:0008038 101 0.689
morphogenesis of a polarized epithelium GO:0001738 93 0.688
Fly
biological adhesion GO:0022610 138 0.681
Fly
localization of cell GO:0051674 257 0.671
head development GO:0060322 135 0.659
Zebrafish
regulation of phosphate metabolic process GO:0019220 210 0.654
Mouse
cell growth GO:0016049 108 0.652
response to wounding GO:0009611 94 0.642
negative regulation of programmed cell death GO:0043069 72 0.642
stem cell maintenance GO:0019827 67 0.620
axon extension GO:0048675 32 0.610
positive regulation of rna metabolic process GO:0051254 271 0.608
Human Mouse
eye morphogenesis GO:0048592 260 0.608
Zebrafish Fly
organelle fission GO:0048285 340 0.606
digestive tract development GO:0048565 149 0.602
regulation of nervous system development GO:0051960 248 0.598
hair cell differentiation GO:0035315 47 0.595
Fly
axonogenesis GO:0007409 290 0.583
nuclear division GO:0000280 332 0.577
gland development GO:0048732 191 0.566
regulation of phosphorylation GO:0042325 147 0.560
Mouse
negative regulation of apoptotic process GO:0043066 63 0.542
cell cell adhesion via plasma membrane adhesion molecules GO:0098742 26 0.532
Fly
cell recognition GO:0008037 102 0.526
regulation of secretion by cell GO:1903530 39 0.517
synaptic growth at neuromuscular junction GO:0051124 119 0.513
compound eye photoreceptor fate commitment GO:0001752 36 0.509
Fly
exocrine system development GO:0035272 162 0.505
negative regulation of cellular macromolecule biosynthetic process GO:2000113 267 0.504
Mouse
negative regulation of gene expression GO:0010629 387 0.500
Mouse
body morphogenesis GO:0010171 2 0.492
regulation of cellular localization GO:0060341 136 0.490
establishment of ommatidial planar polarity GO:0042067 49 0.486
Fly
regulation of synapse organization GO:0050807 110 0.470
negative regulation of multicellular organismal process GO:0051241 142 0.467
secretion GO:0046903 109 0.465
cell junction organization GO:0034330 57 0.452
Mouse
cell cell signaling involved in cell fate commitment GO:0045168 210 0.450
Human
gliogenesis GO:0042063 80 0.450
Zebrafish
negative regulation of cell communication GO:0010648 223 0.448
Zebrafish Fly
hindgut development GO:0061525 58 0.447
motor neuron axon guidance GO:0008045 58 0.443
connective tissue development GO:0061448 3 0.443
compound eye development GO:0048749 307 0.442
Fly
positive regulation of nervous system development GO:0051962 69 0.434
neuron projection extension GO:1990138 32 0.428
branching morphogenesis of an epithelial tube GO:0048754 45 0.428
positive regulation of signaling GO:0023056 243 0.427
Mouse
regulation of developmental growth GO:0048638 174 0.424
regionalization GO:0003002 416 0.424
Human Zebrafish Fly
formation of organ boundary GO:0010160 30 0.423
Fly
epidermal cell differentiation GO:0009913 51 0.422
Fly
negative regulation of macromolecule biosynthetic process GO:0010558 270 0.421
Mouse
secretion by cell GO:0032940 101 0.419
establishment of planar polarity GO:0001736 87 0.418
Fly
somatic stem cell maintenance GO:0035019 14 0.414
compound eye photoreceptor cell differentiation GO:0001751 140 0.401
Fly
negative regulation of developmental process GO:0051093 201 0.399
regulation of cellular component biogenesis GO:0044087 201 0.393
Mouse Fly
regulation of wnt signaling pathway GO:0030111 68 0.390
Zebrafish Mouse
negative regulation of signal transduction GO:0009968 206 0.384
Zebrafish Fly
developmental growth GO:0048589 280 0.382
positive regulation of cell communication GO:0010647 250 0.382
Mouse
positive regulation of response to stimulus GO:0048584 323 0.377
Mouse
neural precursor cell proliferation GO:0061351 75 0.377
ameboidal type cell migration GO:0001667 151 0.370
Fly
response to biotic stimulus GO:0009607 294 0.370
Human
establishment of tissue polarity GO:0007164 87 0.369
Fly
asymmetric cell division GO:0008356 37 0.365
Fly
regulation of dendrite morphogenesis GO:0048814 28 0.359
compound eye retinal cell programmed cell death GO:0046667 23 0.358
malpighian tubule morphogenesis GO:0007443 44 0.354
stem cell differentiation GO:0048863 117 0.352
positive regulation of biosynthetic process GO:0009891 316 0.351
Human Mouse
regulation of transport GO:0051049 181 0.348
negative regulation of signaling GO:0023057 219 0.347
Zebrafish Fly
positive regulation of multicellular organismal process GO:0051240 143 0.343
Human
epithelial tube morphogenesis GO:0060562 88 0.337
respiratory system development GO:0060541 213 0.330
Fly
regulation of synapse assembly GO:0051963 94 0.330
renal tubule morphogenesis GO:0061333 44 0.327
branch fusion open tracheal system GO:0035147 17 0.324
regulation of cell death GO:0010941 173 0.316
response to external biotic stimulus GO:0043207 293 0.298
Human
cellular response to chemical stimulus GO:0070887 199 0.288
synaptic target recognition GO:0008039 45 0.286
regulation of anatomical structure morphogenesis GO:0022603 242 0.284
morphogenesis of embryonic epithelium GO:0016331 94 0.284
cellular protein modification process GO:0006464 438 0.283
Mouse
positive regulation of macromolecule metabolic process GO:0010604 405 0.282
Human Mouse
regulation of stem cell proliferation GO:0072091 40 0.281
cellular response to organic substance GO:0071310 132 0.278
programmed cell death GO:0012501 257 0.276
Mouse
cell death GO:0008219 279 0.270
Mouse
regulation of gene expression epigenetic GO:0040029 128 0.267
renal system development GO:0072001 72 0.264
skin development GO:0043588 65 0.261
Fly
negative regulation of heart induction by canonical wnt signaling pathway GO:0003136 3 0.257
positive regulation of synapse assembly GO:0051965 29 0.253
retina development in camera type eye GO:0060041 4 0.253
negative regulation of cell differentiation GO:0045596 143 0.251
regulation of cell development GO:0060284 215 0.250
protein modification process GO:0036211 438 0.248
Mouse
negative regulation of biosynthetic process GO:0009890 277 0.246
Mouse
urogenital system development GO:0001655 72 0.245
death GO:0016265 284 0.244
Mouse
positive regulation of developmental process GO:0051094 143 0.243
proteolysis GO:0006508 192 0.236
establishment of organelle localization GO:0051656 122 0.236
developmental programmed cell death GO:0010623 138 0.236
Mouse
regulation of secretion GO:0051046 44 0.230
eye photoreceptor cell differentiation GO:0001754 145 0.230
Fly
extrinsic apoptotic signaling pathway GO:0097191 1 0.228
regulation of protein localization GO:0032880 76 0.228
negative regulation of transcription from rna polymerase ii promoter GO:0000122 119 0.227
Mouse
epidermis development GO:0008544 65 0.227
Fly
positive regulation of catabolic process GO:0009896 105 0.224
r3 r4 cell differentiation GO:0048056 12 0.223
Fly
malpighian tubule development GO:0072002 64 0.219
regulation of synaptic growth at neuromuscular junction GO:0008582 89 0.219
organic substance transport GO:0071702 257 0.217
catabolic process GO:0009056 409 0.217
head involution GO:0008258 35 0.216
positive regulation of nitrogen compound metabolic process GO:0051173 354 0.216
Human Mouse
regulation of neural precursor cell proliferation GO:2000177 35 0.216
regulation of catabolic process GO:0009894 170 0.213
apoptotic process GO:0006915 159 0.210
Mouse
regulation of axon extension GO:0030516 8 0.210
positive regulation of cell migration GO:0030335 2 0.209
neuron fate commitment GO:0048663 50 0.208
Fly
organ formation GO:0048645 39 0.205
Fly
stem cell development GO:0048864 79 0.205
regulation of response to stress GO:0080134 200 0.205
Mouse
muscle organ development GO:0007517 127 0.204
unidimensional cell growth GO:0009826 15 0.204
neuroblast development GO:0014019 13 0.204
non sensory hair organization GO:0035316 47 0.203
Fly
kidney epithelium development GO:0072073 3 0.203
regulation of response to external stimulus GO:0032101 115 0.202
stem cell proliferation GO:0072089 88 0.201
mesoderm morphogenesis GO:0048332 22 0.198
negative regulation of cell death GO:0060548 81 0.198
hindgut morphogenesis GO:0007442 58 0.195
cell projection assembly GO:0030031 94 0.194
positive regulation of rna biosynthetic process GO:1902680 266 0.193
Human Mouse
imaginal disc pattern formation GO:0007447 91 0.189
regulation of cell proliferation GO:0042127 163 0.189
regulation of axonogenesis GO:0050770 32 0.189
apical junction assembly GO:0043297 32 0.188
Mouse
positive regulation of compound eye retinal cell programmed cell death GO:0046672 9 0.187
establishment of cell polarity GO:0030010 40 0.185
Fly
phosphorylation GO:0016310 294 0.184
Mouse
cellular catabolic process GO:0044248 372 0.183
regulation of intracellular signal transduction GO:1902531 236 0.181
Mouse
regulation of gliogenesis GO:0014013 11 0.180
positive regulation of gene expression GO:0010628 290 0.180
Human Mouse
cellular protein catabolic process GO:0044257 83 0.179
meiotic cell cycle GO:0051321 171 0.177
open tracheal system development GO:0007424 204 0.176
Fly
imaginal disc derived wing hair site selection GO:0035320 4 0.175
Fly
positive regulation of cell differentiation GO:0045597 64 0.175
imaginal disc derived leg morphogenesis GO:0007480 80 0.174
neuroblast differentiation GO:0014016 29 0.173
response to endogenous stimulus GO:0009719 119 0.172
synaptic transmission GO:0007268 288 0.172
regulation of apoptotic process GO:0042981 130 0.172
negative regulation of growth GO:0045926 84 0.171
epithelial cell differentiation GO:0030855 322 0.170
Fly
positive regulation of retinal cell programmed cell death GO:0046670 9 0.169
mesoderm development GO:0007498 78 0.168
meiotic nuclear division GO:0007126 151 0.168
neuron projection guidance GO:0097485 241 0.166
camera type eye development GO:0043010 4 0.162
Zebrafish Mouse
positive regulation of catalytic activity GO:0043085 118 0.161
Mouse
regulation of cellular component movement GO:0051270 42 0.160
regulation of cell migration GO:0030334 22 0.158
chaeta development GO:0022416 97 0.155
negative regulation of developmental growth GO:0048640 64 0.154
response to other organism GO:0051707 293 0.152
Human
segment polarity determination GO:0007367 25 0.151
regulation of neurogenesis GO:0050767 158 0.151
negative regulation of cellular biosynthetic process GO:0031327 277 0.151
Mouse
embryo development ending in birth or egg hatching GO:0009792 152 0.150
Mouse
sensory perception of chemical stimulus GO:0007606 116 0.150
regulation of cell cycle process GO:0010564 181 0.148
photoreceptor cell differentiation GO:0046530 170 0.146
Fly
cell adhesion GO:0007155 136 0.140
Fly
neurotransmitter secretion GO:0007269 35 0.140
spermatid differentiation GO:0048515 114 0.140
aromatic compound catabolic process GO:0019439 166 0.140
regulation of compound eye retinal cell programmed cell death GO:0046669 18 0.138
negative regulation of cellular metabolic process GO:0031324 382 0.138
Mouse
negative regulation of transcription dna templated GO:0045892 237 0.136
Mouse
embryonic organ morphogenesis GO:0048562 5 0.136
Zebrafish
nucleobase containing small molecule metabolic process GO:0055086 174 0.135
compound eye morphogenesis GO:0001745 249 0.134
Fly
wnt signaling pathway planar cell polarity pathway GO:0060071 6 0.134
positive regulation of cellular biosynthetic process GO:0031328 316 0.130
Human Mouse
single organism cellular localization GO:1902580 180 0.129
ommatidial rotation GO:0016318 20 0.129
Fly
positive regulation of phosphorus metabolic process GO:0010562 139 0.128
Mouse
cell fate specification GO:0001708 71 0.128
negative regulation of cell development GO:0010721 62 0.126
regulation of compound eye pigmentation GO:0048076 7 0.126
regulation of cellular response to stress GO:0080135 89 0.125
Mouse
outflow tract morphogenesis GO:0003151 4 0.125
filopodium assembly GO:0046847 33 0.124
enzyme linked receptor protein signaling pathway GO:0007167 179 0.124
purine nucleoside metabolic process GO:0042278 127 0.118
establishment of epithelial cell apical basal polarity GO:0045198 10 0.118
Fly
transcription from rna polymerase ii promoter GO:0006366 368 0.117
Human Mouse
regulation of protein metabolic process GO:0051246 256 0.116
Mouse
organelle localization GO:0051640 148 0.116
regulation of protein modification process GO:0031399 112 0.116
Mouse
response to organic substance GO:0010033 284 0.116
Human
vesicle mediated transport GO:0016192 381 0.116
positive regulation of transcription dna templated GO:0045893 266 0.115
Human Mouse
negative regulation of rna metabolic process GO:0051253 251 0.115
Mouse
positive regulation of phosphorylation GO:0042327 87 0.112
Mouse
embryonic organ development GO:0048568 50 0.112
Zebrafish Mouse
epithelial cell proliferation involved in malpighian tubule morphogenesis GO:0061331 11 0.111
regulation of heart induction GO:0090381 3 0.111
establishment of protein localization GO:0045184 163 0.110
cellular carbohydrate metabolic process GO:0044262 22 0.109
intracellular signal transduction GO:0035556 300 0.109
Mouse
regulation of cell cycle GO:0051726 291 0.108
smoothened signaling pathway GO:0007224 49 0.107
negative regulation of intracellular signal transduction GO:1902532 57 0.107
retinal ganglion cell axon guidance GO:0031290 12 0.106
regulation of transcription from rna polymerase ii promoter GO:0006357 378 0.106
Human Mouse
protein transport GO:0015031 155 0.106
single organism cell adhesion GO:0098602 47 0.106
chemotaxis GO:0006935 249 0.104
protein modification by small protein conjugation or removal GO:0070647 106 0.104
negative regulation of nervous system development GO:0051961 92 0.104
positive regulation of cell development GO:0010720 61 0.104
negative regulation of cell proliferation GO:0008285 69 0.103
Mouse
cardiovascular system development GO:0072358 82 0.103
Mouse
posttranscriptional gene silencing GO:0016441 46 0.103
gastrulation involving germ band extension GO:0010004 36 0.102
negative regulation of cell cycle process GO:0010948 109 0.102
dorsal ventral pattern formation imaginal disc GO:0007450 51 0.101
intracellular transport GO:0046907 228 0.101
negative regulation of neurogenesis GO:0050768 53 0.100
ventral midline development GO:0007418 9 0.100
wing disc pattern formation GO:0035222 66 0.100
nucleotide catabolic process GO:0009166 109 0.099
regulation of cell projection organization GO:0031344 92 0.098
positive regulation of phosphate metabolic process GO:0045937 139 0.096
Mouse
regulation of cell morphogenesis involved in differentiation GO:0010769 61 0.096
neural retina development GO:0003407 4 0.096
regulation of organ morphogenesis GO:2000027 78 0.096
synaptic vesicle transport GO:0048489 50 0.096
wound healing GO:0042060 75 0.093
lateral inhibition GO:0046331 206 0.093
larval lymph gland hemocyte differentiation GO:0035168 11 0.093
branching involved in open tracheal system development GO:0060446 45 0.092
regulation of cellular catabolic process GO:0031329 157 0.092
regulation of protein phosphorylation GO:0001932 64 0.091
Mouse
regulation of antimicrobial peptide production GO:0002784 44 0.091
periodic partitioning GO:0007365 29 0.090
apoptotic signaling pathway GO:0097190 27 0.088
germ line stem cell maintenance GO:0030718 50 0.087
regulation of embryonic development GO:0045995 68 0.087
mitotic nuclear division GO:0007067 213 0.086
single organism intracellular transport GO:1902582 207 0.086
single organism catabolic process GO:0044712 228 0.085
neurological system process GO:0050877 358 0.084
protein maturation GO:0051604 71 0.082
epithelial cell proliferation involved in renal tubule morphogenesis GO:2001013 11 0.082
ribonucleoside metabolic process GO:0009119 127 0.081
cell cell adhesion GO:0098609 26 0.081
Fly
macromolecule catabolic process GO:0009057 161 0.081
intracellular protein transport GO:0006886 104 0.080
epithelial cell development GO:0002064 274 0.080
Fly
positive regulation of cell death GO:0010942 69 0.080
cytoplasmic transport GO:0016482 130 0.080
telencephalon development GO:0021537 2 0.079
positive regulation of protein catabolic process GO:0045732 34 0.079
limb development GO:0060173 1 0.078
positive regulation of wnt signaling pathway GO:0030177 25 0.077
ribonucleoside catabolic process GO:0042454 112 0.076
regulation of synaptic transmission GO:0050804 69 0.075
positive regulation of signal transduction GO:0009967 223 0.075
Mouse
regulation of phosphorus metabolic process GO:0051174 210 0.075
Mouse
nucleus localization GO:0051647 34 0.074
cellular amine metabolic process GO:0044106 12 0.073
maintenance of location GO:0051235 73 0.073
regulation of proteolysis GO:0030162 87 0.073
regulation of membrane potential GO:0042391 35 0.073
regulation of immune system process GO:0002682 176 0.072
positive regulation of cell motility GO:2000147 3 0.072
regulation of multi organism process GO:0043900 131 0.072
heart induction GO:0003129 3 0.072
peptidyl threonine phosphorylation GO:0018107 2 0.072
negative regulation of synaptic growth at neuromuscular junction GO:0045886 39 0.071
oxoacid metabolic process GO:0043436 103 0.071
humoral immune response GO:0006959 117 0.071
formation of anatomical boundary GO:0048859 37 0.071
Fly
regulation of neuron projection development GO:0010975 69 0.070
developmental cell growth GO:0048588 52 0.070
protein catabolic process GO:0030163 101 0.070
cellular response to mechanical stimulus GO:0071260 2 0.069
axon guidance GO:0007411 233 0.069
regulation of peptidase activity GO:0052547 39 0.069
purine ribonucleoside metabolic process GO:0046128 127 0.068
morphogenesis of a branching epithelium GO:0061138 45 0.067
Mouse
positive regulation of protein phosphorylation GO:0001934 34 0.067
Mouse
retinal cell programmed cell death GO:0046666 25 0.066
regulation of neuron differentiation GO:0045664 103 0.066
negative regulation of immune system process GO:0002683 50 0.066
regulation of cellular protein metabolic process GO:0032268 243 0.066
Mouse
nucleoside phosphate catabolic process GO:1901292 110 0.065
cell migration involved in gastrulation GO:0042074 9 0.064
regulation of growth GO:0040008 233 0.063
regulation of cellular ketone metabolic process GO:0010565 3 0.063
positive regulation of cellular catabolic process GO:0031331 95 0.063
negative regulation of nitrogen compound metabolic process GO:0051172 265 0.062
Mouse
glycosyl compound catabolic process GO:1901658 112 0.062
vesicle localization GO:0051648 55 0.062
morphogenesis of a branching structure GO:0001763 45 0.061
Mouse
positive regulation of secretion GO:0051047 22 0.059
establishment of vesicle localization GO:0051650 51 0.059
larval development GO:0002164 104 0.058
negative regulation of dna endoreduplication GO:0032876 2 0.057
positive regulation of nucleobase containing compound metabolic process GO:0045935 332 0.057
Human Mouse
regulation of programmed cell death GO:0043067 152 0.057
positive regulation of nucleic acid templated transcription GO:1903508 266 0.056
Human Mouse
negative regulation of nucleic acid templated transcription GO:1903507 240 0.056
Mouse
convergent extension GO:0060026 2 0.056
organ induction GO:0001759 3 0.056
regulation of organelle organization GO:0033043 196 0.055
Fly
cellular protein localization GO:0034613 160 0.054
regulation of retinal cell programmed cell death GO:0046668 18 0.053
gene silencing GO:0016458 138 0.053
nucleoside triphosphate metabolic process GO:0009141 120 0.053
positive regulation of protein transport GO:0051222 37 0.052
regulation of cardioblast cell fate specification GO:0042686 8 0.052
forebrain development GO:0030900 2 0.052
Zebrafish
adherens junction assembly GO:0034333 11 0.052
histone modification GO:0016570 106 0.051
nephron epithelium development GO:0072009 3 0.051
positive regulation of cellular protein metabolic process GO:0032270 118 0.051
Mouse
response to growth factor GO:0070848 31 0.051
purine ribonucleotide catabolic process GO:0009154 109 0.050
nucleobase containing compound catabolic process GO:0034655 165 0.049
developmental induction GO:0031128 3 0.049
Human
purine containing compound catabolic process GO:0072523 112 0.049
gastrulation with mouth forming first GO:0001703 36 0.048
regulation of cysteine type endopeptidase activity involved in apoptotic process GO:0043281 25 0.048
regulation of cell fate specification GO:0042659 27 0.048
negative regulation of cellular component organization GO:0051129 108 0.048
regulation of phosphatase activity GO:0010921 3 0.048
positive regulation of synaptic growth at neuromuscular junction GO:0045887 26 0.048
positive regulation of cell proliferation GO:0008284 47 0.047
regulation of mitotic cell cycle GO:0007346 190 0.047
regulation of eye pigmentation GO:0048073 7 0.047
immune system process GO:0002376 347 0.047
positive regulation of exocytosis GO:0045921 4 0.047
positive regulation of growth GO:0045927 75 0.047
regulation of cell motility GO:2000145 23 0.047
response to hormone GO:0009725 45 0.046
glial cell development GO:0021782 27 0.046
carbohydrate derivative catabolic process GO:1901136 118 0.046
leg disc development GO:0035218 92 0.046
negative regulation of rna biosynthetic process GO:1902679 240 0.046
Mouse
peripheral nervous system development GO:0007422 52 0.045
axon extension involved in axon guidance GO:0048846 10 0.044
posttranscriptional gene silencing by rna GO:0035194 45 0.044
cardiac cell fate commitment GO:0060911 17 0.044
regulation of cellular amino acid metabolic process GO:0006521 0 0.044
chaeta morphogenesis GO:0008407 42 0.044
regulation of humoral immune response GO:0002920 51 0.043
regulation of autophagy GO:0010506 62 0.043
regulation of endopeptidase activity GO:0052548 36 0.043
regulation of axon extension involved in axon guidance GO:0048841 4 0.043
peptidyl amino acid modification GO:0018193 105 0.043
regulation of mapk cascade GO:0043408 92 0.043
Mouse
larval lymph gland hemopoiesis GO:0035167 17 0.042
spindle localization GO:0051653 22 0.042
establishment of spindle orientation GO:0051294 18 0.042
photoreceptor cell fate commitment GO:0046552 41 0.042
Fly
nucleoside metabolic process GO:0009116 127 0.042
germ cell migration GO:0008354 43 0.041
kidney development GO:0001822 3 0.041
central nervous system development GO:0007417 201 0.041
Zebrafish
embryonic pattern specification GO:0009880 174 0.041
Human
negative regulation of heart induction GO:1901320 3 0.041
positive regulation of transcription from rna polymerase ii promoter GO:0045944 204 0.040
Human Mouse
muscle tissue development GO:0060537 30 0.040
regulation of cell fate commitment GO:0010453 29 0.040
regulation of neurotransmitter levels GO:0001505 38 0.040
ribonucleotide catabolic process GO:0009261 109 0.039
organic substance catabolic process GO:1901575 308 0.038
regulation of protein transport GO:0051223 57 0.038
leg disc morphogenesis GO:0007478 80 0.038
organophosphate metabolic process GO:0019637 195 0.038
regulation of reproductive process GO:2000241 54 0.038
positive regulation of axon extension GO:0045773 2 0.038
protein deubiquitination GO:0016579 17 0.037
negative regulation of fibroblast growth factor receptor signaling pathway GO:0040037 2 0.037
autophagy GO:0006914 108 0.037
adherens junction organization GO:0034332 27 0.037
regulation of cellular amine metabolic process GO:0033238 3 0.037
regulation of cellular component size GO:0032535 98 0.037
small molecule metabolic process GO:0044281 305 0.036
regulation of organ formation GO:0003156 3 0.036
tissue death GO:0016271 102 0.036
antimicrobial peptide biosynthetic process GO:0002777 38 0.036
negative regulation of cardiac cell fate specification GO:2000044 7 0.036
purine containing compound metabolic process GO:0072521 155 0.035
positive regulation of cellular amino acid metabolic process GO:0045764 0 0.035
negative regulation of neuron differentiation GO:0045665 16 0.035
cell cycle phase transition GO:0044770 140 0.034
antimicrobial humoral response GO:0019730 99 0.034
regulation of neurotransmitter secretion GO:0046928 14 0.034
ubiquitin dependent protein catabolic process GO:0006511 78 0.034
positive regulation of secretion by cell GO:1903532 20 0.034
regulation of cell shape GO:0008360 113 0.034
positive regulation of proteolysis involved in cellular protein catabolic process GO:1903052 24 0.034
cellular macromolecule localization GO:0070727 220 0.034
detection of stimulus involved in sensory perception GO:0050906 92 0.034
axon choice point recognition GO:0016198 26 0.034
regulation of protein catabolic process GO:0042176 55 0.033
ovarian follicle cell development GO:0030707 248 0.033
Fly
actin filament based process GO:0030029 220 0.033
Fly
lipid localization GO:0010876 54 0.033
positive regulation of organelle organization GO:0010638 65 0.033
cellular nitrogen compound catabolic process GO:0044270 165 0.032
actin filament organization GO:0007015 126 0.032
Fly
regulation of dendrite development GO:0050773 37 0.032
r3 r4 cell fate commitment GO:0007464 10 0.032
Fly
hindbrain development GO:0030902 2 0.032
purine ribonucleoside catabolic process GO:0046130 112 0.032
production of molecular mediator of immune response GO:0002440 46 0.032
rna processing GO:0006396 147 0.032
neuron migration GO:0001764 5 0.032
regulation of cytoskeleton organization GO:0051493 89 0.031
Fly
hemocyte migration GO:0035099 19 0.031
regulation of glial cell differentiation GO:0045685 1 0.031
cellular response to endogenous stimulus GO:0071495 80 0.031
embryonic hemopoiesis GO:0035162 26 0.031
neuron fate determination GO:0048664 1 0.031
cardioblast cell fate specification GO:0042685 9 0.031
cell surface receptor signaling pathway involved in heart development GO:0061311 3 0.030

fz2 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in fly and predicted with the fly functional network.

Disease DO term ID Size Probability Func Analog Org
organ system cancer DOID:0050686 0 0.046
disease of cellular proliferation DOID:14566 0 0.046
cancer DOID:162 0 0.046