Drosophila melanogaster

123 known processes

fz2 (Dmel_CG9739)

frizzled 2

(Aliases: fz-2,Dfz[[2]],dfz2,Dmel\CG9739,D-Fz2,FZ2,Dfrz2,dfz2r,D-fz2,Dfz2,CG9739,dFz2,Fz2,frz2,DFz-2,DFZ2,DFz2,dfz(2))

fz2 biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
imaginal disc derived appendage morphogenesis GO:0035114 395 0.997
morphogenesis of an epithelium GO:0002009 276 0.996
Mouse Fly
tissue morphogenesis GO:0048729 297 0.993
Mouse Fly
post embryonic appendage morphogenesis GO:0035120 385 0.991
appendage morphogenesis GO:0035107 397 0.991
synapse organization GO:0050808 196 0.991
tube morphogenesis GO:0035239 191 0.990
imaginal disc derived wing margin morphogenesis GO:0008587 41 0.987
wing disc morphogenesis GO:0007472 344 0.978
appendage development GO:0048736 401 0.973
dorsal ventral pattern formation GO:0009953 133 0.973
Human Zebrafish
imaginal disc derived appendage development GO:0048737 399 0.971
tube development GO:0035295 244 0.964
digestive tract morphogenesis GO:0048546 127 0.956
digestive system development GO:0055123 149 0.955
imaginal disc derived wing morphogenesis GO:0007476 337 0.947
embryonic morphogenesis GO:0048598 206 0.942
Zebrafish Mouse
signal release GO:0023061 49 0.934
synapse assembly GO:0007416 143 0.919
regulation of synapse structure and activity GO:0050803 128 0.915
dendrite morphogenesis GO:0048813 199 0.914
wnt signaling pathway GO:0016055 98 0.907
gastrulation GO:0007369 70 0.903
growth GO:0040007 359 0.896
regulation of localization GO:0032879 275 0.896
gland morphogenesis GO:0022612 145 0.887
regulation of multicellular organismal development GO:2000026 414 0.882
cell junction assembly GO:0034329 42 0.876
Mouse
neuroblast proliferation GO:0007405 74 0.862
neuromuscular junction development GO:0007528 149 0.858
salivary gland development GO:0007431 162 0.856
imaginal disc derived wing hair organization GO:0035317 45 0.841
Fly
eye development GO:0001654 323 0.840
Zebrafish Mouse Fly
eye photoreceptor cell fate commitment GO:0042706 37 0.835
Fly
dendrite development GO:0016358 204 0.824
developmental growth involved in morphogenesis GO:0060560 65 0.801
salivary gland morphogenesis GO:0007435 145 0.796
cell motility GO:0048870 251 0.790
sensory organ morphogenesis GO:0090596 260 0.781
Zebrafish Fly
embryonic development via the syncytial blastoderm GO:0001700 148 0.780
neurotransmitter transport GO:0006836 37 0.779
regulation of anatomical structure size GO:0090066 163 0.777
Fly
establishment or maintenance of cell polarity GO:0007163 167 0.772
Fly
establishment of localization in cell GO:0051649 402 0.770
cell migration GO:0016477 238 0.756
regulation of cell morphogenesis GO:0022604 163 0.753
axon development GO:0061564 297 0.738
establishment of imaginal disc derived wing hair orientation GO:0001737 24 0.732
Fly
dorsal closure GO:0007391 79 0.697
non canonical wnt signaling pathway GO:0035567 8 0.696
Zebrafish
regulation of cell differentiation GO:0045595 302 0.690
neuron recognition GO:0008038 101 0.689
morphogenesis of a polarized epithelium GO:0001738 93 0.688
Fly
biological adhesion GO:0022610 138 0.681
Fly
localization of cell GO:0051674 257 0.671
head development GO:0060322 135 0.659
Zebrafish
regulation of phosphate metabolic process GO:0019220 210 0.654
Mouse
cell growth GO:0016049 108 0.652
response to wounding GO:0009611 94 0.642
negative regulation of programmed cell death GO:0043069 72 0.642
stem cell maintenance GO:0019827 67 0.620
axon extension GO:0048675 32 0.610
positive regulation of rna metabolic process GO:0051254 271 0.608
Human Mouse
eye morphogenesis GO:0048592 260 0.608
Zebrafish Fly
organelle fission GO:0048285 340 0.606
digestive tract development GO:0048565 149 0.602
regulation of nervous system development GO:0051960 248 0.598
hair cell differentiation GO:0035315 47 0.595
Fly
axonogenesis GO:0007409 290 0.583
nuclear division GO:0000280 332 0.577
gland development GO:0048732 191 0.566
regulation of phosphorylation GO:0042325 147 0.560
Mouse
negative regulation of apoptotic process GO:0043066 63 0.542
cell cell adhesion via plasma membrane adhesion molecules GO:0098742 26 0.532
Fly
cell recognition GO:0008037 102 0.526
regulation of secretion by cell GO:1903530 39 0.517
synaptic growth at neuromuscular junction GO:0051124 119 0.513
compound eye photoreceptor fate commitment GO:0001752 36 0.509
Fly
exocrine system development GO:0035272 162 0.505
negative regulation of cellular macromolecule biosynthetic process GO:2000113 267 0.504
Mouse
negative regulation of gene expression GO:0010629 387 0.500
Mouse
body morphogenesis GO:0010171 2 0.492
regulation of cellular localization GO:0060341 136 0.490
establishment of ommatidial planar polarity GO:0042067 49 0.486
Fly
regulation of synapse organization GO:0050807 110 0.470
negative regulation of multicellular organismal process GO:0051241 142 0.467
secretion GO:0046903 109 0.465
cell junction organization GO:0034330 57 0.452
Mouse
cell cell signaling involved in cell fate commitment GO:0045168 210 0.450
Human
gliogenesis GO:0042063 80 0.450
Zebrafish
negative regulation of cell communication GO:0010648 223 0.448
Zebrafish Fly
hindgut development GO:0061525 58 0.447
motor neuron axon guidance GO:0008045 58 0.443
connective tissue development GO:0061448 3 0.443
compound eye development GO:0048749 307 0.442
Fly
positive regulation of nervous system development GO:0051962 69 0.434
neuron projection extension GO:1990138 32 0.428
branching morphogenesis of an epithelial tube GO:0048754 45 0.428
positive regulation of signaling GO:0023056 243 0.427
Mouse
regulation of developmental growth GO:0048638 174 0.424
regionalization GO:0003002 416 0.424
Human Zebrafish Fly
formation of organ boundary GO:0010160 30 0.423
Fly
epidermal cell differentiation GO:0009913 51 0.422
Fly
negative regulation of macromolecule biosynthetic process GO:0010558 270 0.421
Mouse
secretion by cell GO:0032940 101 0.419
establishment of planar polarity GO:0001736 87 0.418
Fly
somatic stem cell maintenance GO:0035019 14 0.414
compound eye photoreceptor cell differentiation GO:0001751 140 0.401
Fly
negative regulation of developmental process GO:0051093 201 0.399
regulation of cellular component biogenesis GO:0044087 201 0.393
Mouse Fly
regulation of wnt signaling pathway GO:0030111 68 0.390
Zebrafish Mouse
negative regulation of signal transduction GO:0009968 206 0.384
Zebrafish Fly
developmental growth GO:0048589 280 0.382
positive regulation of cell communication GO:0010647 250 0.382
Mouse
positive regulation of response to stimulus GO:0048584 323 0.377
Mouse
neural precursor cell proliferation GO:0061351 75 0.377
ameboidal type cell migration GO:0001667 151 0.370
Fly
response to biotic stimulus GO:0009607 294 0.370
Human
establishment of tissue polarity GO:0007164 87 0.369
Fly
asymmetric cell division GO:0008356 37 0.365
Fly
regulation of dendrite morphogenesis GO:0048814 28 0.359
compound eye retinal cell programmed cell death GO:0046667 23 0.358
malpighian tubule morphogenesis GO:0007443 44 0.354
stem cell differentiation GO:0048863 117 0.352
positive regulation of biosynthetic process GO:0009891 316 0.351
Human Mouse
regulation of transport GO:0051049 181 0.348
negative regulation of signaling GO:0023057 219 0.347
Zebrafish Fly
positive regulation of multicellular organismal process GO:0051240 143 0.343
Human
epithelial tube morphogenesis GO:0060562 88 0.337
respiratory system development GO:0060541 213 0.330
Fly
regulation of synapse assembly GO:0051963 94 0.330
renal tubule morphogenesis GO:0061333 44 0.327
branch fusion open tracheal system GO:0035147 17 0.324
regulation of cell death GO:0010941 173 0.316
response to external biotic stimulus GO:0043207 293 0.298
Human
cellular response to chemical stimulus GO:0070887 199 0.288
synaptic target recognition GO:0008039 45 0.286
regulation of anatomical structure morphogenesis GO:0022603 242 0.284
morphogenesis of embryonic epithelium GO:0016331 94 0.284
cellular protein modification process GO:0006464 438 0.283
Mouse
positive regulation of macromolecule metabolic process GO:0010604 405 0.282
Human Mouse
regulation of stem cell proliferation GO:0072091 40 0.281
cellular response to organic substance GO:0071310 132 0.278
programmed cell death GO:0012501 257 0.276
Mouse
cell death GO:0008219 279 0.270
Mouse
regulation of gene expression epigenetic GO:0040029 128 0.267
renal system development GO:0072001 72 0.264
skin development GO:0043588 65 0.261
Fly
negative regulation of heart induction by canonical wnt signaling pathway GO:0003136 3 0.257
positive regulation of synapse assembly GO:0051965 29 0.253
retina development in camera type eye GO:0060041 4 0.253
negative regulation of cell differentiation GO:0045596 143 0.251
regulation of cell development GO:0060284 215 0.250
protein modification process GO:0036211 438 0.248
Mouse
negative regulation of biosynthetic process GO:0009890 277 0.246
Mouse
urogenital system development GO:0001655 72 0.245
death GO:0016265 284 0.244
Mouse
positive regulation of developmental process GO:0051094 143 0.243
proteolysis GO:0006508 192 0.236
establishment of organelle localization GO:0051656 122 0.236
developmental programmed cell death GO:0010623 138 0.236
Mouse
regulation of secretion GO:0051046 44 0.230
eye photoreceptor cell differentiation GO:0001754 145 0.230
Fly
extrinsic apoptotic signaling pathway GO:0097191 1 0.228
regulation of protein localization GO:0032880 76 0.228
negative regulation of transcription from rna polymerase ii promoter GO:0000122 119 0.227
Mouse
epidermis development GO:0008544 65 0.227
Fly
positive regulation of catabolic process GO:0009896 105 0.224
r3 r4 cell differentiation GO:0048056 12 0.223
Fly
malpighian tubule development GO:0072002 64 0.219
regulation of synaptic growth at neuromuscular junction GO:0008582 89 0.219
organic substance transport GO:0071702 257 0.217
catabolic process GO:0009056 409 0.217
head involution GO:0008258 35 0.216
positive regulation of nitrogen compound metabolic process GO:0051173 354 0.216
Human Mouse
regulation of neural precursor cell proliferation GO:2000177 35 0.216
regulation of catabolic process GO:0009894 170 0.213
apoptotic process GO:0006915 159 0.210
Mouse
regulation of axon extension GO:0030516 8 0.210
positive regulation of cell migration GO:0030335 2 0.209
neuron fate commitment GO:0048663 50 0.208
Fly
organ formation GO:0048645 39 0.205
Fly
stem cell development GO:0048864 79 0.205
regulation of response to stress GO:0080134 200 0.205
Mouse
muscle organ development GO:0007517 127 0.204
unidimensional cell growth GO:0009826 15 0.204
neuroblast development GO:0014019 13 0.204
non sensory hair organization GO:0035316 47 0.203
Fly
kidney epithelium development GO:0072073 3 0.203
regulation of response to external stimulus GO:0032101 115 0.202
stem cell proliferation GO:0072089 88 0.201
mesoderm morphogenesis GO:0048332 22 0.198
negative regulation of cell death GO:0060548 81 0.198
hindgut morphogenesis GO:0007442 58 0.195
cell projection assembly GO:0030031 94 0.194
positive regulation of rna biosynthetic process GO:1902680 266 0.193
Human Mouse
imaginal disc pattern formation GO:0007447 91 0.189
regulation of cell proliferation GO:0042127 163 0.189
regulation of axonogenesis GO:0050770 32 0.189
apical junction assembly GO:0043297 32 0.188
Mouse
positive regulation of compound eye retinal cell programmed cell death GO:0046672 9 0.187
establishment of cell polarity GO:0030010 40 0.185
Fly
phosphorylation GO:0016310 294 0.184
Mouse
cellular catabolic process GO:0044248 372 0.183
regulation of intracellular signal transduction GO:1902531 236 0.181
Mouse
regulation of gliogenesis GO:0014013 11 0.180
positive regulation of gene expression GO:0010628 290 0.180
Human Mouse
cellular protein catabolic process GO:0044257 83 0.179
meiotic cell cycle GO:0051321 171 0.177
open tracheal system development GO:0007424 204 0.176
Fly
imaginal disc derived wing hair site selection GO:0035320 4 0.175
Fly
positive regulation of cell differentiation GO:0045597 64 0.175
imaginal disc derived leg morphogenesis GO:0007480 80 0.174
neuroblast differentiation GO:0014016 29 0.173
response to endogenous stimulus GO:0009719 119 0.172
synaptic transmission GO:0007268 288 0.172
regulation of apoptotic process GO:0042981 130 0.172
negative regulation of growth GO:0045926 84 0.171
epithelial cell differentiation GO:0030855 322 0.170
Fly
positive regulation of retinal cell programmed cell death GO:0046670 9 0.169
mesoderm development GO:0007498 78 0.168
meiotic nuclear division GO:0007126 151 0.168
neuron projection guidance GO:0097485 241 0.166
camera type eye development GO:0043010 4 0.162
Zebrafish Mouse
positive regulation of catalytic activity GO:0043085 118 0.161
Mouse
regulation of cellular component movement GO:0051270 42 0.160
regulation of cell migration GO:0030334 22 0.158
chaeta development GO:0022416 97 0.155
negative regulation of developmental growth GO:0048640 64 0.154
response to other organism GO:0051707 293 0.152
Human
segment polarity determination GO:0007367 25 0.151
regulation of neurogenesis GO:0050767 158 0.151
negative regulation of cellular biosynthetic process GO:0031327 277 0.151
Mouse
embryo development ending in birth or egg hatching GO:0009792 152 0.150
Mouse
sensory perception of chemical stimulus GO:0007606 116 0.150
regulation of cell cycle process GO:0010564 181 0.148
photoreceptor cell differentiation GO:0046530 170 0.146
Fly
cell adhesion GO:0007155 136 0.140
Fly
neurotransmitter secretion GO:0007269 35 0.140
spermatid differentiation GO:0048515 114 0.140
aromatic compound catabolic process GO:0019439 166 0.140
regulation of compound eye retinal cell programmed cell death GO:0046669 18 0.138
negative regulation of cellular metabolic process GO:0031324 382 0.138
Mouse
negative regulation of transcription dna templated GO:0045892 237 0.136
Mouse
embryonic organ morphogenesis GO:0048562 5 0.136
Zebrafish
nucleobase containing small molecule metabolic process GO:0055086 174 0.135
compound eye morphogenesis GO:0001745 249 0.134
Fly
wnt signaling pathway planar cell polarity pathway GO:0060071 6 0.134
positive regulation of cellular biosynthetic process GO:0031328 316 0.130
Human Mouse
single organism cellular localization GO:1902580 180 0.129
ommatidial rotation GO:0016318 20 0.129
Fly
positive regulation of phosphorus metabolic process GO:0010562 139 0.128
Mouse
cell fate specification GO:0001708 71 0.128
negative regulation of cell development GO:0010721 62 0.126
regulation of compound eye pigmentation GO:0048076 7 0.126
regulation of cellular response to stress GO:0080135 89 0.125
Mouse
outflow tract morphogenesis GO:0003151 4 0.125
filopodium assembly GO:0046847 33 0.124
enzyme linked receptor protein signaling pathway GO:0007167 179 0.124
purine nucleoside metabolic process GO:0042278 127 0.118
establishment of epithelial cell apical basal polarity GO:0045198 10 0.118
Fly
transcription from rna polymerase ii promoter GO:0006366 368 0.117
Human Mouse
regulation of protein metabolic process GO:0051246 256 0.116
Mouse
organelle localization GO:0051640 148 0.116
regulation of protein modification process GO:0031399 112 0.116
Mouse
response to organic substance GO:0010033 284 0.116
Human
vesicle mediated transport GO:0016192 381 0.116
positive regulation of transcription dna templated GO:0045893 266 0.115
Human Mouse
negative regulation of rna metabolic process GO:0051253 251 0.115
Mouse
positive regulation of phosphorylation GO:0042327 87 0.112
Mouse
embryonic organ development GO:0048568 50 0.112
Zebrafish Mouse
epithelial cell proliferation involved in malpighian tubule morphogenesis GO:0061331 11 0.111
regulation of heart induction GO:0090381 3 0.111
establishment of protein localization GO:0045184 163 0.110
cellular carbohydrate metabolic process GO:0044262 22 0.109
intracellular signal transduction GO:0035556 300 0.109
Mouse
regulation of cell cycle GO:0051726 291 0.108
smoothened signaling pathway GO:0007224 49 0.107
negative regulation of intracellular signal transduction GO:1902532 57 0.107
retinal ganglion cell axon guidance GO:0031290 12 0.106
regulation of transcription from rna polymerase ii promoter GO:0006357 378 0.106
Human Mouse
protein transport GO:0015031 155 0.106
single organism cell adhesion GO:0098602 47 0.106
chemotaxis GO:0006935 249 0.104
protein modification by small protein conjugation or removal GO:0070647 106 0.104
negative regulation of nervous system development GO:0051961 92 0.104
positive regulation of cell development GO:0010720 61 0.104
negative regulation of cell proliferation GO:0008285 69 0.103
Mouse
cardiovascular system development GO:0072358 82 0.103
Mouse
posttranscriptional gene silencing GO:0016441 46 0.103
gastrulation involving germ band extension GO:0010004 36 0.102
negative regulation of cell cycle process GO:0010948 109 0.102
dorsal ventral pattern formation imaginal disc GO:0007450 51 0.101
intracellular transport GO:0046907 228 0.101
negative regulation of neurogenesis GO:0050768 53 0.100
ventral midline development GO:0007418 9 0.100
wing disc pattern formation GO:0035222 66 0.100
nucleotide catabolic process GO:0009166 109 0.099
regulation of cell projection organization GO:0031344 92 0.098
positive regulation of phosphate metabolic process GO:0045937 139 0.096
Mouse
regulation of cell morphogenesis involved in differentiation GO:0010769 61 0.096
neural retina development GO:0003407 4 0.096
regulation of organ morphogenesis GO:2000027 78 0.096
synaptic vesicle transport GO:0048489 50 0.096
wound healing GO:0042060 75 0.093
lateral inhibition GO:0046331 206 0.093
larval lymph gland hemocyte differentiation GO:0035168 11 0.093
branching involved in open tracheal system development GO:0060446 45 0.092
regulation of cellular catabolic process GO:0031329 157 0.092
regulation of protein phosphorylation GO:0001932 64 0.091
Mouse
regulation of antimicrobial peptide production GO:0002784 44 0.091
periodic partitioning GO:0007365 29 0.090
apoptotic signaling pathway GO:0097190 27 0.088
germ line stem cell maintenance GO:0030718 50 0.087
regulation of embryonic development GO:0045995 68 0.087
mitotic nuclear division GO:0007067 213 0.086
single organism intracellular transport GO:1902582 207 0.086
single organism catabolic process GO:0044712 228 0.085
neurological system process GO:0050877 358 0.084
protein maturation GO:0051604 71 0.082
epithelial cell proliferation involved in renal tubule morphogenesis GO:2001013 11 0.082
ribonucleoside metabolic process GO:0009119 127 0.081
cell cell adhesion GO:0098609 26 0.081
Fly
macromolecule catabolic process GO:0009057 161 0.081
intracellular protein transport GO:0006886 104 0.080
epithelial cell development GO:0002064 274 0.080
Fly
positive regulation of cell death GO:0010942 69 0.080
cytoplasmic transport GO:0016482 130 0.080
telencephalon development GO:0021537 2 0.079
positive regulation of protein catabolic process GO:0045732 34 0.079
limb development GO:0060173 1 0.078
positive regulation of wnt signaling pathway GO:0030177 25 0.077
ribonucleoside catabolic process GO:0042454 112 0.076
regulation of synaptic transmission GO:0050804 69 0.075
positive regulation of signal transduction GO:0009967 223 0.075
Mouse
regulation of phosphorus metabolic process GO:0051174 210 0.075
Mouse
nucleus localization GO:0051647 34 0.074
cellular amine metabolic process GO:0044106 12 0.073
maintenance of location GO:0051235 73 0.073
regulation of proteolysis GO:0030162 87 0.073
regulation of membrane potential GO:0042391 35 0.073
regulation of immune system process GO:0002682 176 0.072
positive regulation of cell motility GO:2000147 3 0.072
regulation of multi organism process GO:0043900 131 0.072
heart induction GO:0003129 3 0.072
peptidyl threonine phosphorylation GO:0018107 2 0.072
negative regulation of synaptic growth at neuromuscular junction GO:0045886 39 0.071
oxoacid metabolic process GO:0043436 103 0.071
humoral immune response GO:0006959 117 0.071
formation of anatomical boundary GO:0048859 37 0.071
Fly
regulation of neuron projection development GO:0010975 69 0.070
developmental cell growth GO:0048588 52 0.070
protein catabolic process GO:0030163 101 0.070
cellular response to mechanical stimulus GO:0071260 2 0.069
axon guidance GO:0007411 233 0.069
regulation of peptidase activity GO:0052547 39 0.069
purine ribonucleoside metabolic process GO:0046128 127 0.068
morphogenesis of a branching epithelium GO:0061138 45 0.067
Mouse
positive regulation of protein phosphorylation GO:0001934 34 0.067
Mouse
retinal cell programmed cell death GO:0046666 25 0.066
regulation of neuron differentiation GO:0045664 103 0.066
negative regulation of immune system process GO:0002683 50 0.066
regulation of cellular protein metabolic process GO:0032268 243 0.066
Mouse
nucleoside phosphate catabolic process GO:1901292 110 0.065
cell migration involved in gastrulation GO:0042074 9 0.064
regulation of growth GO:0040008 233 0.063
regulation of cellular ketone metabolic process GO:0010565 3 0.063
positive regulation of cellular catabolic process GO:0031331 95 0.063
negative regulation of nitrogen compound metabolic process GO:0051172 265 0.062
Mouse
glycosyl compound catabolic process GO:1901658 112 0.062
vesicle localization GO:0051648 55 0.062
morphogenesis of a branching structure GO:0001763 45 0.061
Mouse
positive regulation of secretion GO:0051047 22 0.059
establishment of vesicle localization GO:0051650 51 0.059
larval development GO:0002164 104 0.058
negative regulation of dna endoreduplication GO:0032876 2 0.057
positive regulation of nucleobase containing compound metabolic process GO:0045935 332 0.057
Human Mouse
regulation of programmed cell death GO:0043067 152 0.057
positive regulation of nucleic acid templated transcription GO:1903508 266 0.056
Human Mouse
negative regulation of nucleic acid templated transcription GO:1903507 240 0.056
Mouse
convergent extension GO:0060026 2 0.056
organ induction GO:0001759 3 0.056
regulation of organelle organization GO:0033043 196 0.055
Fly
cellular protein localization GO:0034613 160 0.054
regulation of retinal cell programmed cell death GO:0046668 18 0.053
gene silencing GO:0016458 138 0.053
nucleoside triphosphate metabolic process GO:0009141 120 0.053
positive regulation of protein transport GO:0051222 37 0.052
regulation of cardioblast cell fate specification GO:0042686 8 0.052
forebrain development GO:0030900 2 0.052
Zebrafish
adherens junction assembly GO:0034333 11 0.052
histone modification GO:0016570 106 0.051
nephron epithelium development GO:0072009 3 0.051
positive regulation of cellular protein metabolic process GO:0032270 118 0.051
Mouse
response to growth factor GO:0070848 31 0.051
purine ribonucleotide catabolic process GO:0009154 109 0.050
nucleobase containing compound catabolic process GO:0034655 165 0.049
developmental induction GO:0031128 3 0.049
Human
purine containing compound catabolic process GO:0072523 112 0.049
gastrulation with mouth forming first GO:0001703 36 0.048
regulation of cysteine type endopeptidase activity involved in apoptotic process GO:0043281 25 0.048
regulation of cell fate specification GO:0042659 27 0.048
negative regulation of cellular component organization GO:0051129 108 0.048
regulation of phosphatase activity GO:0010921 3 0.048
positive regulation of synaptic growth at neuromuscular junction GO:0045887 26 0.048
positive regulation of cell proliferation GO:0008284 47 0.047
regulation of mitotic cell cycle GO:0007346 190 0.047
regulation of eye pigmentation GO:0048073 7 0.047
immune system process GO:0002376 347 0.047
positive regulation of exocytosis GO:0045921 4 0.047
positive regulation of growth GO:0045927 75 0.047
regulation of cell motility GO:2000145 23 0.047
response to hormone GO:0009725 45 0.046
glial cell development GO:0021782 27 0.046
carbohydrate derivative catabolic process GO:1901136 118 0.046
leg disc development GO:0035218 92 0.046
negative regulation of rna biosynthetic process GO:1902679 240 0.046
Mouse
peripheral nervous system development GO:0007422 52 0.045
axon extension involved in axon guidance GO:0048846 10 0.044
posttranscriptional gene silencing by rna GO:0035194 45 0.044
cardiac cell fate commitment GO:0060911 17 0.044
regulation of cellular amino acid metabolic process GO:0006521 0 0.044
chaeta morphogenesis GO:0008407 42 0.044
regulation of humoral immune response GO:0002920 51 0.043
regulation of autophagy GO:0010506 62 0.043
regulation of endopeptidase activity GO:0052548 36 0.043
regulation of axon extension involved in axon guidance GO:0048841 4 0.043
peptidyl amino acid modification GO:0018193 105 0.043
regulation of mapk cascade GO:0043408 92 0.043
Mouse
larval lymph gland hemopoiesis GO:0035167 17 0.042
spindle localization GO:0051653 22 0.042
establishment of spindle orientation GO:0051294 18 0.042
photoreceptor cell fate commitment GO:0046552 41 0.042
Fly
nucleoside metabolic process GO:0009116 127 0.042
germ cell migration GO:0008354 43 0.041
kidney development GO:0001822 3 0.041
central nervous system development GO:0007417 201 0.041
Zebrafish
embryonic pattern specification GO:0009880 174 0.041
Human
negative regulation of heart induction GO:1901320 3 0.041
positive regulation of transcription from rna polymerase ii promoter GO:0045944 204 0.040
Human Mouse
muscle tissue development GO:0060537 30 0.040
regulation of cell fate commitment GO:0010453 29 0.040
regulation of neurotransmitter levels GO:0001505 38 0.040
ribonucleotide catabolic process GO:0009261 109 0.039
organic substance catabolic process GO:1901575 308 0.038
regulation of protein transport GO:0051223 57 0.038
leg disc morphogenesis GO:0007478 80 0.038
organophosphate metabolic process GO:0019637 195 0.038
regulation of reproductive process GO:2000241 54 0.038
positive regulation of axon extension GO:0045773 2 0.038
protein deubiquitination GO:0016579 17 0.037
negative regulation of fibroblast growth factor receptor signaling pathway GO:0040037 2 0.037
autophagy GO:0006914 108 0.037
adherens junction organization GO:0034332 27 0.037
regulation of cellular amine metabolic process GO:0033238 3 0.037
regulation of cellular component size GO:0032535 98 0.037
small molecule metabolic process GO:0044281 305 0.036
regulation of organ formation GO:0003156 3 0.036
tissue death GO:0016271 102 0.036
antimicrobial peptide biosynthetic process GO:0002777 38 0.036
negative regulation of cardiac cell fate specification GO:2000044 7 0.036
purine containing compound metabolic process GO:0072521 155 0.035
positive regulation of cellular amino acid metabolic process GO:0045764 0 0.035
negative regulation of neuron differentiation GO:0045665 16 0.035
cell cycle phase transition GO:0044770 140 0.034
antimicrobial humoral response GO:0019730 99 0.034
regulation of neurotransmitter secretion GO:0046928 14 0.034
ubiquitin dependent protein catabolic process GO:0006511 78 0.034
positive regulation of secretion by cell GO:1903532 20 0.034
regulation of cell shape GO:0008360 113 0.034
positive regulation of proteolysis involved in cellular protein catabolic process GO:1903052 24 0.034
cellular macromolecule localization GO:0070727 220 0.034
detection of stimulus involved in sensory perception GO:0050906 92 0.034
axon choice point recognition GO:0016198 26 0.034
regulation of protein catabolic process GO:0042176 55 0.033
ovarian follicle cell development GO:0030707 248 0.033
Fly
actin filament based process GO:0030029 220 0.033
Fly
lipid localization GO:0010876 54 0.033
positive regulation of organelle organization GO:0010638 65 0.033
cellular nitrogen compound catabolic process GO:0044270 165 0.032
actin filament organization GO:0007015 126 0.032
Fly
regulation of dendrite development GO:0050773 37 0.032
r3 r4 cell fate commitment GO:0007464 10 0.032
Fly
hindbrain development GO:0030902 2 0.032
purine ribonucleoside catabolic process GO:0046130 112 0.032
production of molecular mediator of immune response GO:0002440 46 0.032
rna processing GO:0006396 147 0.032
neuron migration GO:0001764 5 0.032
regulation of cytoskeleton organization GO:0051493 89 0.031
Fly
hemocyte migration GO:0035099 19 0.031
regulation of glial cell differentiation GO:0045685 1 0.031
cellular response to endogenous stimulus GO:0071495 80 0.031
embryonic hemopoiesis GO:0035162 26 0.031
neuron fate determination GO:0048664 1 0.031
cardioblast cell fate specification GO:0042685 9 0.031
cell surface receptor signaling pathway involved in heart development GO:0061311 3 0.030

fz2 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in fly and predicted with the fly functional network.

Disease DO term ID Size Probability Func Analog Org
cancer DOID:162 0 0.046
disease of cellular proliferation DOID:14566 0 0.046
organ system cancer DOID:0050686 0 0.046