Drosophila melanogaster

56 known processes

vls (Dmel_CG10728)

valois

(Aliases: Dmel\CG10728,CG107278,CG10728,val,38B.5)

vls biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
oocyte differentiation GO:0009994 145 0.972
anterior posterior axis specification GO:0009948 109 0.966
pole plasm assembly GO:0007315 61 0.963
axis specification GO:0009798 167 0.917
oocyte anterior posterior axis specification GO:0007314 72 0.839
cell maturation GO:0048469 144 0.828
oocyte axis specification GO:0007309 108 0.813
pole plasm rna localization GO:0007316 52 0.804
maternal determination of anterior posterior axis embryo GO:0008358 74 0.788
anterior posterior axis specification embryo GO:0008595 103 0.751
oocyte construction GO:0007308 112 0.727
cytoplasm organization GO:0007028 64 0.724
embryonic axis specification GO:0000578 107 0.694
blastoderm segmentation GO:0007350 159 0.682
oocyte development GO:0048599 124 0.679
segmentation GO:0035282 207 0.667
rna localization GO:0006403 115 0.618
pole plasm oskar mrna localization GO:0045451 46 0.540
pole cell formation GO:0007279 19 0.534
anterior posterior pattern specification GO:0009952 136 0.503
regionalization GO:0003002 416 0.477
intracellular mrna localization GO:0008298 66 0.446
tripartite regional subdivision GO:0007351 103 0.432
cellularization GO:0007349 90 0.408
embryonic pattern specification GO:0009880 174 0.365
regulation of pole plasm oskar mrna localization GO:0007317 27 0.361
developmental maturation GO:0021700 172 0.357
pole plasm protein localization GO:0007318 10 0.268
chromosome organization GO:0051276 360 0.261
dorsal ventral pattern formation GO:0009953 133 0.256
ribonucleoprotein complex subunit organization GO:0071826 28 0.243
columnar cuboidal epithelial cell differentiation GO:0002065 256 0.242
Mouse
pole plasm mrna localization GO:0019094 49 0.230
pole cell development GO:0007277 26 0.227
organelle fission GO:0048285 340 0.226
cellular macromolecule localization GO:0070727 220 0.219
nuclear division GO:0000280 332 0.207
positive regulation of macromolecule metabolic process GO:0010604 405 0.164
regulation of cellular component biogenesis GO:0044087 201 0.159
karyosome formation GO:0030717 22 0.150
macromolecular complex assembly GO:0065003 256 0.150
meiotic cell cycle GO:0051321 171 0.126
catabolic process GO:0009056 409 0.124
organic substance catabolic process GO:1901575 308 0.121
gene silencing GO:0016458 138 0.120
axonogenesis GO:0007409 290 0.115
negative regulation of cellular macromolecule biosynthetic process GO:2000113 267 0.115
meiotic cell cycle process GO:1903046 132 0.109
rna processing GO:0006396 147 0.109
eggshell formation GO:0030703 105 0.103
protein localization GO:0008104 284 0.103
establishment of organelle localization GO:0051656 122 0.097
protein complex biogenesis GO:0070271 201 0.094
mitochondrion organization GO:0007005 65 0.093
organelle localization GO:0051640 148 0.092
cellular macromolecule catabolic process GO:0044265 136 0.090
macromolecule catabolic process GO:0009057 161 0.087
purine nucleoside catabolic process GO:0006152 112 0.085
meiotic nuclear division GO:0007126 151 0.078
immune system process GO:0002376 347 0.077
chromosome segregation GO:0007059 157 0.076
negative regulation of rna biosynthetic process GO:1902679 240 0.072
columnar cuboidal epithelial cell development GO:0002066 249 0.070
carbohydrate derivative catabolic process GO:1901136 118 0.068
organic cyclic compound catabolic process GO:1901361 168 0.068
positive regulation of transcription dna templated GO:0045893 266 0.068
negative regulation of macromolecule biosynthetic process GO:0010558 270 0.068
negative regulation of rna metabolic process GO:0051253 251 0.067
cellular catabolic process GO:0044248 372 0.065
germarium derived egg chamber formation GO:0007293 101 0.065
posttranscriptional gene silencing GO:0016441 46 0.064
microtubule organizing center organization GO:0031023 168 0.063
protein modification process GO:0036211 438 0.063
regulation of cell cycle GO:0051726 291 0.062
gene silencing by rna GO:0031047 57 0.060
proteasomal protein catabolic process GO:0010498 59 0.059
negative regulation of cellular metabolic process GO:0031324 382 0.058
regulation of immune effector process GO:0002697 52 0.057
negative regulation of gene expression GO:0010629 387 0.057
cellular protein modification process GO:0006464 438 0.057
female meiotic division GO:0007143 70 0.056
heterocycle catabolic process GO:0046700 166 0.056
intracellular mrna localization involved in anterior posterior axis specification GO:0060811 53 0.053
mrna metabolic process GO:0016071 124 0.051
epithelial cell differentiation GO:0030855 322 0.050
Mouse
organonitrogen compound metabolic process GO:1901564 318 0.050
mitotic nuclear division GO:0007067 213 0.049
epithelial cell development GO:0002064 274 0.048
aromatic compound catabolic process GO:0019439 166 0.047
spindle organization GO:0007051 253 0.046
positive regulation of signal transduction GO:0009967 223 0.046
cellular macromolecular complex assembly GO:0034622 153 0.046
intracellular transport GO:0046907 228 0.045
death GO:0016265 284 0.045
cell migration GO:0016477 238 0.045
single organism cellular localization GO:1902580 180 0.045
regulation of protein complex assembly GO:0043254 42 0.044
cellular protein complex assembly GO:0043623 71 0.044
regulation of intracellular signal transduction GO:1902531 236 0.041
positive regulation of macromolecule biosynthetic process GO:0010557 283 0.040
meiosis i GO:0007127 59 0.040
guanosine containing compound catabolic process GO:1901069 74 0.040
immune response GO:0006955 246 0.040
positive regulation of nucleic acid templated transcription GO:1903508 266 0.040
transcription from rna polymerase ii promoter GO:0006366 368 0.039
Mouse
regulation of protein metabolic process GO:0051246 256 0.039
nucleoside phosphate metabolic process GO:0006753 162 0.039
regulation of establishment of protein localization GO:0070201 61 0.038
positive regulation of response to stimulus GO:0048584 323 0.038
ribonucleoside catabolic process GO:0042454 112 0.038
protein complex assembly GO:0006461 200 0.038
positive regulation of cellular component biogenesis GO:0044089 80 0.036
nucleoside triphosphate catabolic process GO:0009143 108 0.036
programmed cell death GO:0012501 257 0.036
cellular response to dna damage stimulus GO:0006974 223 0.035
single organism intracellular transport GO:1902582 207 0.034
ras protein signal transduction GO:0007265 88 0.033
enzyme linked receptor protein signaling pathway GO:0007167 179 0.033
cellular component assembly involved in morphogenesis GO:0010927 151 0.032
purine ribonucleotide catabolic process GO:0009154 109 0.032
positive regulation of gene expression GO:0010628 290 0.032
nucleotide catabolic process GO:0009166 109 0.032
ribonucleotide catabolic process GO:0009261 109 0.031
dendrite morphogenesis GO:0048813 199 0.031
regulation of response to stress GO:0080134 200 0.030
tissue morphogenesis GO:0048729 297 0.030
positive regulation of organelle organization GO:0010638 65 0.029
purine nucleoside triphosphate metabolic process GO:0009144 119 0.029
cellular protein catabolic process GO:0044257 83 0.028
gtp metabolic process GO:0046039 72 0.028
purine nucleotide catabolic process GO:0006195 109 0.027
protein ubiquitination GO:0016567 70 0.027
chorion containing eggshell formation GO:0007304 105 0.027
carbohydrate derivative metabolic process GO:1901135 217 0.027
nucleobase containing small molecule metabolic process GO:0055086 174 0.027
protein modification by small protein conjugation or removal GO:0070647 106 0.026
positive regulation of cell communication GO:0010647 250 0.026
cellular nitrogen compound catabolic process GO:0044270 165 0.026
negative regulation of biosynthetic process GO:0009890 277 0.026
stem cell division GO:0017145 69 0.026
signal transduction by phosphorylation GO:0023014 107 0.026
dorsal appendage formation GO:0046843 47 0.025
proteolysis GO:0006508 192 0.025
maintenance of protein location in cell GO:0032507 26 0.025
establishment of localization in cell GO:0051649 402 0.025
regulation of mapk cascade GO:0043408 92 0.025
mapk cascade GO:0000165 107 0.025
protein catabolic process GO:0030163 101 0.025
mitotic spindle organization GO:0007052 220 0.025
regulation of cellular protein metabolic process GO:0032268 243 0.025
regulation of multicellular organismal development GO:2000026 414 0.025
Mouse
spermatogenesis GO:0007283 200 0.024
neuromuscular junction development GO:0007528 149 0.024
positive regulation of cellular component organization GO:0051130 156 0.024
protein modification by small protein conjugation GO:0032446 79 0.024
glycosyl compound catabolic process GO:1901658 112 0.024
ribonucleoside triphosphate catabolic process GO:0009203 108 0.024
regulation of reproductive process GO:2000241 54 0.023
Mouse
positive regulation of nitrogen compound metabolic process GO:0051173 354 0.023
positive regulation of molecular function GO:0044093 136 0.023
ubiquitin dependent protein catabolic process GO:0006511 78 0.023
regulation of organelle organization GO:0033043 196 0.023
purine containing compound catabolic process GO:0072523 112 0.023
nucleoside catabolic process GO:0009164 112 0.022
positive regulation of rna biosynthetic process GO:1902680 266 0.022
regulation of cell differentiation GO:0045595 302 0.022
purine ribonucleoside metabolic process GO:0046128 127 0.022
ribonucleoprotein complex biogenesis GO:0022613 31 0.022
nucleobase containing compound catabolic process GO:0034655 165 0.022
neuroblast proliferation GO:0007405 74 0.022
dorsal ventral axis specification GO:0009950 66 0.021
ribonucleoside metabolic process GO:0009119 127 0.021
sister chromatid segregation GO:0000819 92 0.021
regulation of multi organism process GO:0043900 131 0.021
positive regulation of protein metabolic process GO:0051247 128 0.021
male meiosis GO:0007140 52 0.021
regulation of cytoskeleton organization GO:0051493 89 0.021
cell death GO:0008219 279 0.021
glycosyl compound metabolic process GO:1901657 127 0.020
ovarian follicle cell development GO:0030707 248 0.020
negative regulation of signal transduction GO:0009968 206 0.020
mitotic sister chromatid segregation GO:0000070 87 0.020
response to organic substance GO:0010033 284 0.020
positive regulation of signaling GO:0023056 243 0.019
regulation of cell cycle process GO:0010564 181 0.019
proteolysis involved in cellular protein catabolic process GO:0051603 83 0.019
defense response to other organism GO:0098542 225 0.019
actin nucleation GO:0045010 8 0.019
regulation of ras protein signal transduction GO:0046578 93 0.019
regulation of nuclear division GO:0051783 58 0.019
regulation of transport GO:0051049 181 0.019
cellular response to chemical stimulus GO:0070887 199 0.018
regulation of meiosis GO:0040020 3 0.018
localization of cell GO:0051674 257 0.018
axon development GO:0061564 297 0.018
guanosine containing compound metabolic process GO:1901068 74 0.018
organonitrogen compound catabolic process GO:1901565 128 0.018
nucleotide metabolic process GO:0009117 161 0.018
eggshell chorion assembly GO:0007306 66 0.018
small gtpase mediated signal transduction GO:0007264 88 0.018
regulation of proteolysis involved in cellular protein catabolic process GO:1903050 44 0.018
long term memory GO:0007616 62 0.018
purine ribonucleoside catabolic process GO:0046130 112 0.018
male gamete generation GO:0048232 201 0.018
germarium derived oocyte differentiation GO:0030706 29 0.017
embryo development ending in birth or egg hatching GO:0009792 152 0.017
response to biotic stimulus GO:0009607 294 0.017
negative regulation of cell proliferation GO:0008285 69 0.017
Mouse
intracellular mrna localization involved in pattern specification process GO:0060810 56 0.017
nucleoside phosphate catabolic process GO:1901292 110 0.017
small molecule metabolic process GO:0044281 305 0.017
regulation of molecular function GO:0065009 217 0.016
positive regulation of biosynthetic process GO:0009891 316 0.016
regulation of protein catabolic process GO:0042176 55 0.016
response to external biotic stimulus GO:0043207 293 0.016
response to other organism GO:0051707 293 0.016
modification dependent protein catabolic process GO:0019941 78 0.015
mrna processing GO:0006397 104 0.015
cellular response to organic substance GO:0071310 132 0.015
production of molecular mediator of immune response GO:0002440 46 0.015
regulation of cellular response to stress GO:0080135 89 0.015
negative regulation of protein metabolic process GO:0051248 85 0.015
negative regulation of cell communication GO:0010648 223 0.015
synaptic growth at neuromuscular junction GO:0051124 119 0.015
proteasome mediated ubiquitin dependent protein catabolic process GO:0043161 54 0.015
modification dependent macromolecule catabolic process GO:0043632 79 0.014
vesicle mediated transport GO:0016192 381 0.014
regulation of gene expression epigenetic GO:0040029 128 0.014
regulation of synapse structure and activity GO:0050803 128 0.014
nucleoside metabolic process GO:0009116 127 0.014
posttranscriptional gene silencing by rna GO:0035194 45 0.014
apoptotic process GO:0006915 159 0.014
negative regulation of transcription dna templated GO:0045892 237 0.014
purine ribonucleoside triphosphate metabolic process GO:0009205 119 0.014
posttranscriptional regulation of gene expression GO:0010608 145 0.014
negative regulation of nucleobase containing compound metabolic process GO:0045934 261 0.014
cell motility GO:0048870 251 0.014
ribonucleoside monophosphate catabolic process GO:0009158 39 0.013
chromatin organization GO:0006325 207 0.013
positive regulation of intracellular signal transduction GO:1902533 116 0.013
rna catabolic process GO:0006401 37 0.013
chromatin modification GO:0016568 147 0.013
oocyte dorsal ventral axis specification GO:0007310 34 0.013
cell proliferation GO:0008283 299 0.013
Mouse
regulation of cell development GO:0060284 215 0.013
cognition GO:0050890 141 0.013
rna phosphodiester bond hydrolysis GO:0090501 17 0.013
dna conformation change GO:0071103 105 0.013
organelle assembly GO:0070925 198 0.013
nucleoside triphosphate metabolic process GO:0009141 120 0.012
gtp catabolic process GO:0006184 72 0.012
positive regulation of protein complex assembly GO:0031334 22 0.012
mitotic cytokinesis GO:0000281 50 0.012
growth GO:0040007 359 0.012
negative regulation of developmental process GO:0051093 201 0.012
Mouse
regulation of localization GO:0032879 275 0.012
nuclear transcribed mrna catabolic process GO:0000956 24 0.012
regulation of catalytic activity GO:0050790 185 0.012
maintenance of location in cell GO:0051651 28 0.012
endocytosis GO:0006897 310 0.012
purine nucleoside metabolic process GO:0042278 127 0.012
purine nucleoside triphosphate catabolic process GO:0009146 108 0.012
ribonucleoprotein complex assembly GO:0022618 23 0.012
regulation of cellular catabolic process GO:0031329 157 0.012
negative regulation of transcription from rna polymerase ii promoter GO:0000122 119 0.012
positive regulation of cell cycle GO:0045787 43 0.012
chromosome condensation GO:0030261 41 0.012
organonitrogen compound biosynthetic process GO:1901566 117 0.012
central nervous system development GO:0007417 201 0.011
negative regulation of response to stimulus GO:0048585 258 0.011
single organism catabolic process GO:0044712 228 0.011
positive regulation of ras protein signal transduction GO:0046579 43 0.011
germarium derived oocyte fate determination GO:0007294 26 0.011
positive regulation of phosphorus metabolic process GO:0010562 139 0.011
ribonucleoside triphosphate metabolic process GO:0009199 119 0.011
regulation of protein transport GO:0051223 57 0.011
response to bacterium GO:0009617 198 0.011
positive regulation of mapk cascade GO:0043410 63 0.010
organic substance transport GO:0071702 257 0.010
dendrite development GO:0016358 204 0.010
protein transport GO:0015031 155 0.010
regulation of cell proliferation GO:0042127 163 0.010
Mouse
response to oxidative stress GO:0006979 86 0.010

vls disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in fly and predicted with the fly functional network.

Disease DO term ID Size Probability Func Analog Org
disease of anatomical entity DOID:7 0 0.017
disease of cellular proliferation DOID:14566 0 0.014
cancer DOID:162 0 0.011
organ system cancer DOID:0050686 0 0.010