|
|
positive regulation of macromolecule metabolic process
|
GO:0010604 |
405 |
0.272
|
Human |
|
|
immune system process
|
GO:0002376 |
347 |
0.221
|
|
|
|
dna packaging
|
GO:0006323 |
91 |
0.137
|
|
|
|
endomembrane system organization
|
GO:0010256 |
119 |
0.111
|
|
|
|
columnar cuboidal epithelial cell development
|
GO:0002066 |
249 |
0.109
|
|
|
|
defense response
|
GO:0006952 |
300 |
0.099
|
|
|
|
post embryonic appendage morphogenesis
|
GO:0035120 |
385 |
0.097
|
|
|
|
stem cell proliferation
|
GO:0072089 |
88 |
0.094
|
|
|
|
single organism biosynthetic process
|
GO:0044711 |
206 |
0.089
|
|
|
|
epithelial cell differentiation
|
GO:0030855 |
322 |
0.079
|
|
|
|
columnar cuboidal epithelial cell differentiation
|
GO:0002065 |
256 |
0.077
|
|
|
|
positive regulation of macromolecule biosynthetic process
|
GO:0010557 |
283 |
0.073
|
Human |
|
|
positive regulation of response to stimulus
|
GO:0048584 |
323 |
0.067
|
|
|
|
establishment of localization in cell
|
GO:0051649 |
402 |
0.067
|
Human Mouse |
|
|
negative regulation of response to stimulus
|
GO:0048585 |
258 |
0.066
|
|
|
|
positive regulation of gene expression
|
GO:0010628 |
290 |
0.064
|
Human |
|
|
notch signaling pathway
|
GO:0007219 |
120 |
0.062
|
|
|
|
cellular amino acid metabolic process
|
GO:0006520 |
61 |
0.062
|
|
|
|
chromatin assembly or disassembly
|
GO:0006333 |
52 |
0.060
|
|
|
|
regulation of cell differentiation
|
GO:0045595 |
302 |
0.060
|
|
|
|
cell division
|
GO:0051301 |
248 |
0.056
|
|
|
|
negative regulation of cellular metabolic process
|
GO:0031324 |
382 |
0.055
|
|
|
|
protein modification by small protein conjugation or removal
|
GO:0070647 |
106 |
0.054
|
|
|
|
establishment of organelle localization
|
GO:0051656 |
122 |
0.054
|
|
|
|
protein modification process
|
GO:0036211 |
438 |
0.052
|
|
|
|
intracellular signal transduction
|
GO:0035556 |
300 |
0.051
|
|
|
|
cell motility
|
GO:0048870 |
251 |
0.051
|
|
|
|
ovarian follicle cell development
|
GO:0030707 |
248 |
0.049
|
|
|
|
epithelial cell development
|
GO:0002064 |
274 |
0.046
|
|
|
|
asymmetric protein localization
|
GO:0008105 |
33 |
0.045
|
|
|
|
regulation of synapse structure and activity
|
GO:0050803 |
128 |
0.044
|
|
|
|
cell migration
|
GO:0016477 |
238 |
0.044
|
|
|
|
positive regulation of biosynthetic process
|
GO:0009891 |
316 |
0.043
|
Human |
|
|
imaginal disc derived appendage development
|
GO:0048737 |
399 |
0.043
|
|
|
|
secretion by cell
|
GO:0032940 |
101 |
0.041
|
|
|
|
negative regulation of cell communication
|
GO:0010648 |
223 |
0.041
|
|
|
|
positive regulation of rna biosynthetic process
|
GO:1902680 |
266 |
0.040
|
|
|
|
organelle localization
|
GO:0051640 |
148 |
0.040
|
|
|
|
regulation of organelle organization
|
GO:0033043 |
196 |
0.040
|
|
|
|
asymmetric stem cell division
|
GO:0098722 |
49 |
0.038
|
|
|
|
secretion
|
GO:0046903 |
109 |
0.037
|
|
|
|
negative regulation of signal transduction
|
GO:0009968 |
206 |
0.037
|
|
|
|
vesicle mediated transport
|
GO:0016192 |
381 |
0.037
|
|
|
|
exocytosis
|
GO:0006887 |
28 |
0.036
|
|
|
|
modification dependent protein catabolic process
|
GO:0019941 |
78 |
0.036
|
|
|
|
positive regulation of rna metabolic process
|
GO:0051254 |
271 |
0.036
|
|
|
|
positive regulation of nucleic acid templated transcription
|
GO:1903508 |
266 |
0.034
|
|
|
|
proteolysis involved in cellular protein catabolic process
|
GO:0051603 |
83 |
0.034
|
|
|
|
localization of cell
|
GO:0051674 |
257 |
0.034
|
|
|
|
cardiovascular system development
|
GO:0072358 |
82 |
0.034
|
|
|
|
neural precursor cell proliferation
|
GO:0061351 |
75 |
0.033
|
|
|
|
intracellular transport
|
GO:0046907 |
228 |
0.033
|
Human Mouse |
|
|
central nervous system development
|
GO:0007417 |
201 |
0.033
|
|
|
|
endocytosis
|
GO:0006897 |
310 |
0.033
|
|
|
|
nuclear division
|
GO:0000280 |
332 |
0.033
|
|
|
|
compound eye development
|
GO:0048749 |
307 |
0.032
|
|
|
|
appendage morphogenesis
|
GO:0035107 |
397 |
0.032
|
|
|
|
regulation of nervous system development
|
GO:0051960 |
248 |
0.031
|
|
|
|
digestive tract morphogenesis
|
GO:0048546 |
127 |
0.031
|
|
|
|
innate immune response
|
GO:0045087 |
144 |
0.030
|
|
|
|
negative regulation of developmental process
|
GO:0051093 |
201 |
0.029
|
|
|
|
organonitrogen compound biosynthetic process
|
GO:1901566 |
117 |
0.029
|
|
|
|
protein ubiquitination
|
GO:0016567 |
70 |
0.029
|
|
|
|
single organism behavior
|
GO:0044708 |
391 |
0.029
|
|
|
|
organonitrogen compound metabolic process
|
GO:1901564 |
318 |
0.029
|
|
|
|
positive regulation of nucleobase containing compound metabolic process
|
GO:0045935 |
332 |
0.029
|
|
|
|
ameboidal type cell migration
|
GO:0001667 |
151 |
0.028
|
|
|
|
positive regulation of cellular biosynthetic process
|
GO:0031328 |
316 |
0.027
|
Human |
|
|
macromolecular complex assembly
|
GO:0065003 |
256 |
0.027
|
|
|
|
positive regulation of cellular protein metabolic process
|
GO:0032270 |
118 |
0.027
|
Human |
|
|
regulation of synapse organization
|
GO:0050807 |
110 |
0.027
|
|
|
|
eye development
|
GO:0001654 |
323 |
0.026
|
|
|
|
single organism cellular localization
|
GO:1902580 |
180 |
0.026
|
|
|
|
leg disc morphogenesis
|
GO:0007478 |
80 |
0.026
|
|
|
|
positive regulation of signal transduction
|
GO:0009967 |
223 |
0.026
|
|
|
|
epithelial cell migration
|
GO:0010631 |
148 |
0.026
|
|
|
|
negative regulation of intracellular signal transduction
|
GO:1902532 |
57 |
0.026
|
|
|
|
positive regulation of cellular amino acid metabolic process
|
GO:0045764 |
0 |
0.026
|
|
|
|
regulation of localization
|
GO:0032879 |
275 |
0.026
|
|
|
|
positive regulation of molecular function
|
GO:0044093 |
136 |
0.025
|
|
|
|
phagocytosis
|
GO:0006909 |
215 |
0.025
|
|
|
|
posttranscriptional regulation of gene expression
|
GO:0010608 |
145 |
0.025
|
Human |
|
|
cellular macromolecule catabolic process
|
GO:0044265 |
136 |
0.024
|
|
|
|
regulation of cellular protein metabolic process
|
GO:0032268 |
243 |
0.024
|
Human |
|
|
stem cell division
|
GO:0017145 |
69 |
0.024
|
|
|
|
macromolecule catabolic process
|
GO:0009057 |
161 |
0.024
|
|
|
|
cell proliferation
|
GO:0008283 |
299 |
0.024
|
|
|
|
neuroblast proliferation
|
GO:0007405 |
74 |
0.023
|
|
|
|
olfactory behavior
|
GO:0042048 |
97 |
0.023
|
|
|
|
imaginal disc derived appendage morphogenesis
|
GO:0035114 |
395 |
0.022
|
|
|
|
negative regulation of signaling
|
GO:0023057 |
219 |
0.022
|
|
|
|
regulation of molecular function
|
GO:0065009 |
217 |
0.022
|
|
|
|
protein complex biogenesis
|
GO:0070271 |
201 |
0.022
|
|
|
|
positive regulation of cell communication
|
GO:0010647 |
250 |
0.021
|
|
|
|
neuronal stem cell division
|
GO:0036445 |
35 |
0.021
|
|
|
|
ovarian follicle cell migration
|
GO:0007297 |
121 |
0.021
|
|
|
|
catabolic process
|
GO:0009056 |
409 |
0.020
|
|
|
|
cellular protein localization
|
GO:0034613 |
160 |
0.020
|
|
|
|
border follicle cell migration
|
GO:0007298 |
113 |
0.020
|
|
|
|
negative regulation of multicellular organismal process
|
GO:0051241 |
142 |
0.020
|
|
|
|
positive regulation of signaling
|
GO:0023056 |
243 |
0.020
|
|
|
|
nucleosome organization
|
GO:0034728 |
59 |
0.020
|
|
|
|
axis specification
|
GO:0009798 |
167 |
0.020
|
|
|
|
cellular nitrogen compound catabolic process
|
GO:0044270 |
165 |
0.019
|
|
|
|
leg disc development
|
GO:0035218 |
92 |
0.019
|
|
|
|
vesicle organization
|
GO:0016050 |
44 |
0.019
|
|
|
|
cell death
|
GO:0008219 |
279 |
0.019
|
|
|
|
chromatin remodeling
|
GO:0006338 |
72 |
0.019
|
|
|
|
regulation of transport
|
GO:0051049 |
181 |
0.019
|
|
|
|
tube morphogenesis
|
GO:0035239 |
191 |
0.018
|
|
|
|
chromosome organization
|
GO:0051276 |
360 |
0.018
|
|
|
|
appendage development
|
GO:0048736 |
401 |
0.018
|
|
|
|
learning or memory
|
GO:0007611 |
141 |
0.018
|
|
|
|
apoptotic process
|
GO:0006915 |
159 |
0.018
|
|
|
|
immune response
|
GO:0006955 |
246 |
0.018
|
|
|
|
regulation of multicellular organismal development
|
GO:2000026 |
414 |
0.018
|
|
|
|
cell fate determination
|
GO:0001709 |
91 |
0.018
|
|
|
|
cellular amine metabolic process
|
GO:0044106 |
12 |
0.017
|
|
|
|
proteolysis
|
GO:0006508 |
192 |
0.017
|
|
|
|
developmental maturation
|
GO:0021700 |
172 |
0.017
|
|
|
|
regulation of apoptotic process
|
GO:0042981 |
130 |
0.017
|
|
|
|
regulation of cellular amine metabolic process
|
GO:0033238 |
3 |
0.017
|
|
|
|
homeostatic process
|
GO:0042592 |
199 |
0.017
|
|
|
|
protein complex disassembly
|
GO:0043241 |
36 |
0.017
|
|
|
|
organelle fission
|
GO:0048285 |
340 |
0.017
|
|
|
|
macromolecular complex disassembly
|
GO:0032984 |
37 |
0.017
|
|
|
|
organic acid metabolic process
|
GO:0006082 |
103 |
0.017
|
|
|
|
body morphogenesis
|
GO:0010171 |
2 |
0.016
|
|
|
|
asymmetric neuroblast division
|
GO:0055059 |
33 |
0.016
|
|
|
|
ras protein signal transduction
|
GO:0007265 |
88 |
0.016
|
|
|
|
organic substance catabolic process
|
GO:1901575 |
308 |
0.016
|
|
|
|
regulation of programmed cell death
|
GO:0043067 |
152 |
0.016
|
|
|
|
protein catabolic process
|
GO:0030163 |
101 |
0.016
|
|
|
|
cellular catabolic process
|
GO:0044248 |
372 |
0.016
|
|
|
|
organelle assembly
|
GO:0070925 |
198 |
0.016
|
|
|
|
positive regulation of cellular amine metabolic process
|
GO:0033240 |
0 |
0.016
|
|
|
|
stem cell differentiation
|
GO:0048863 |
117 |
0.015
|
|
|
|
dna metabolic process
|
GO:0006259 |
227 |
0.015
|
|
|
|
death
|
GO:0016265 |
284 |
0.015
|
|
|
|
response to other organism
|
GO:0051707 |
293 |
0.015
|
|
|
|
imaginal disc derived leg morphogenesis
|
GO:0007480 |
80 |
0.015
|
|
|
|
establishment or maintenance of cell polarity
|
GO:0007163 |
167 |
0.015
|
|
|
|
golgi organization
|
GO:0007030 |
66 |
0.015
|
|
|
|
epithelial tube morphogenesis
|
GO:0060562 |
88 |
0.014
|
|
|
|
imaginal disc derived wing vein morphogenesis
|
GO:0008586 |
44 |
0.014
|
|
|
|
hematopoietic or lymphoid organ development
|
GO:0048534 |
57 |
0.014
|
|
|
|
wound healing
|
GO:0042060 |
75 |
0.014
|
|
|
|
single organism intracellular transport
|
GO:1902582 |
207 |
0.014
|
Human Mouse |
|
|
regulation of cellular amino acid metabolic process
|
GO:0006521 |
0 |
0.014
|
|
|
|
small molecule metabolic process
|
GO:0044281 |
305 |
0.014
|
|
|
|
chromosome condensation
|
GO:0030261 |
41 |
0.014
|
|
|
|
regulation of catalytic activity
|
GO:0050790 |
185 |
0.014
|
|
|
|
regulation of phosphorus metabolic process
|
GO:0051174 |
210 |
0.014
|
|
|
|
carboxylic acid metabolic process
|
GO:0019752 |
92 |
0.014
|
|
|
|
regulation of notch signaling pathway
|
GO:0008593 |
100 |
0.013
|
|
|
|
regulation of vesicle mediated transport
|
GO:0060627 |
59 |
0.013
|
|
|
|
tissue morphogenesis
|
GO:0048729 |
297 |
0.013
|
|
|
|
imaginal disc derived wing morphogenesis
|
GO:0007476 |
337 |
0.013
|
|
|
|
female germline ring canal formation
|
GO:0007301 |
9 |
0.013
|
|
|
|
protein modification by small protein conjugation
|
GO:0032446 |
79 |
0.013
|
|
|
|
modification dependent macromolecule catabolic process
|
GO:0043632 |
79 |
0.013
|
|
|
|
positive regulation of wnt signaling pathway
|
GO:0030177 |
25 |
0.012
|
|
|
|
wing disc morphogenesis
|
GO:0007472 |
344 |
0.012
|
|
|
|
regulation of cellular ketone metabolic process
|
GO:0010565 |
3 |
0.012
|
|
|
|
multi organism behavior
|
GO:0051705 |
175 |
0.012
|
|
|
|
negative regulation of cell differentiation
|
GO:0045596 |
143 |
0.012
|
|
|
|
salivary gland development
|
GO:0007431 |
162 |
0.012
|
|
|
|
chemosensory behavior
|
GO:0007635 |
106 |
0.012
|
|
|
|
histone modification
|
GO:0016570 |
106 |
0.012
|
|
|
|
positive regulation of protein metabolic process
|
GO:0051247 |
128 |
0.012
|
Human |
|
|
eggshell formation
|
GO:0030703 |
105 |
0.012
|
|
|
|
positive regulation of nitrogen compound metabolic process
|
GO:0051173 |
354 |
0.012
|
|
|
|
ocellus pigmentation
|
GO:0033060 |
19 |
0.012
|
|
|
|
proteasome mediated ubiquitin dependent protein catabolic process
|
GO:0043161 |
54 |
0.012
|
|
|
|
positive regulation of catalytic activity
|
GO:0043085 |
118 |
0.012
|
|
|
|
cell projection assembly
|
GO:0030031 |
94 |
0.011
|
|
|
|
regulation of response to stress
|
GO:0080134 |
200 |
0.011
|
Fly |
|
|
anatomical structure homeostasis
|
GO:0060249 |
97 |
0.011
|
|
|
|
oocyte development
|
GO:0048599 |
124 |
0.011
|
|
|
|
signal transduction by phosphorylation
|
GO:0023014 |
107 |
0.011
|
|
|
|
compound eye morphogenesis
|
GO:0001745 |
249 |
0.011
|
|
|
|
protein transport
|
GO:0015031 |
155 |
0.011
|
|
|
|
positive regulation of transcription dna templated
|
GO:0045893 |
266 |
0.011
|
|
|
|
chromatin organization
|
GO:0006325 |
207 |
0.011
|
|
|
|
meiotic nuclear division
|
GO:0007126 |
151 |
0.011
|
|
|
|
regulation of protein complex disassembly
|
GO:0043244 |
29 |
0.011
|
|
|
|
apoptotic cell clearance
|
GO:0043277 |
14 |
0.011
|
|
|
|
protein k48 linked ubiquitination
|
GO:0070936 |
3 |
0.011
|
|
|
|
chromatin modification
|
GO:0016568 |
147 |
0.011
|
|
|
|
establishment of protein localization
|
GO:0045184 |
163 |
0.011
|
|
|
|
embryonic organ development
|
GO:0048568 |
50 |
0.010
|
|
|
|
regulation of intracellular signal transduction
|
GO:1902531 |
236 |
0.010
|
|
|
|
sister chromatid segregation
|
GO:0000819 |
92 |
0.010
|
|
|
|
membrane organization
|
GO:0061024 |
112 |
0.010
|
|
|
|
epidermal growth factor receptor signaling pathway
|
GO:0007173 |
58 |
0.010
|
|
|
|
amine metabolic process
|
GO:0009308 |
12 |
0.010
|
|
|
|
positive regulation of cell migration
|
GO:0030335 |
2 |
0.010
|
|
|
|
reproductive structure development
|
GO:0048608 |
74 |
0.010
|
|