Drosophila melanogaster

61 known processes

tankyrase (Dmel_CG4719)

CG4719 gene product from transcript CG4719-RA

(Aliases: BcDNA:LD22548,Dmel\CG4719,CG4719,CG17487)

tankyrase biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
post embryonic appendage morphogenesis GO:0035120 385 0.294
cell migration GO:0016477 238 0.226
appendage morphogenesis GO:0035107 397 0.200
positive regulation of macromolecule metabolic process GO:0010604 405 0.198
Human
appendage development GO:0048736 401 0.189
regulation of cellular protein metabolic process GO:0032268 243 0.182
columnar cuboidal epithelial cell development GO:0002066 249 0.166
phosphorylation GO:0016310 294 0.154
Human
cellular protein modification process GO:0006464 438 0.151
epithelial cell development GO:0002064 274 0.132
localization of cell GO:0051674 257 0.132
morphogenesis of an epithelium GO:0002009 276 0.125
cell motility GO:0048870 251 0.121
memory GO:0007613 94 0.119
regulation of molecular function GO:0065009 217 0.118
Human
wing disc morphogenesis GO:0007472 344 0.114
ovarian follicle cell development GO:0030707 248 0.112
imaginal disc derived appendage morphogenesis GO:0035114 395 0.111
tissue morphogenesis GO:0048729 297 0.106
regulation of cellular catabolic process GO:0031329 157 0.104
negative regulation of cell differentiation GO:0045596 143 0.098
regulation of catabolic process GO:0009894 170 0.092
salivary gland development GO:0007431 162 0.086
protein modification process GO:0036211 438 0.084
epithelial cell differentiation GO:0030855 322 0.083
regulation of protein metabolic process GO:0051246 256 0.082
positive regulation of gene expression GO:0010628 290 0.079
Human
ameboidal type cell migration GO:0001667 151 0.078
regulation of phosphate metabolic process GO:0019220 210 0.072
amine metabolic process GO:0009308 12 0.069
regulation of cell development GO:0060284 215 0.068
eggshell chorion assembly GO:0007306 66 0.067
organonitrogen compound metabolic process GO:1901564 318 0.065
columnar cuboidal epithelial cell differentiation GO:0002065 256 0.064
regulation of cellular ketone metabolic process GO:0010565 3 0.064
imaginal disc derived wing morphogenesis GO:0007476 337 0.063
positive regulation of catabolic process GO:0009896 105 0.062
regulation of epidermal growth factor receptor signaling pathway GO:0042058 42 0.062
oxoacid metabolic process GO:0043436 103 0.062
actin cytoskeleton organization GO:0030036 206 0.062
cellular catabolic process GO:0044248 372 0.062
negative regulation of cellular metabolic process GO:0031324 382 0.059
exocrine system development GO:0035272 162 0.059
positive regulation of cellular catabolic process GO:0031331 95 0.058
carboxylic acid metabolic process GO:0019752 92 0.057
regulation of cellular amine metabolic process GO:0033238 3 0.057
enzyme linked receptor protein signaling pathway GO:0007167 179 0.055
catabolic process GO:0009056 409 0.054
regulation of catalytic activity GO:0050790 185 0.054
epithelium migration GO:0090132 148 0.052
cellular ketone metabolic process GO:0042180 24 0.052
intracellular transport GO:0046907 228 0.049
regulation of cell projection organization GO:0031344 92 0.049
regulation of cellular amino acid metabolic process GO:0006521 0 0.049
programmed cell death GO:0012501 257 0.046
organic acid metabolic process GO:0006082 103 0.046
regulation of phosphorus metabolic process GO:0051174 210 0.045
ras protein signal transduction GO:0007265 88 0.045
imaginal disc derived appendage development GO:0048737 399 0.044
compound eye development GO:0048749 307 0.044
positive regulation of rna metabolic process GO:0051254 271 0.043
Human
long term memory GO:0007616 62 0.043
positive regulation of transcription from rna polymerase ii promoter GO:0045944 204 0.043
Human
protein localization GO:0008104 284 0.043
Human
regulation of ras protein signal transduction GO:0046578 93 0.042
protein complex biogenesis GO:0070271 201 0.041
response to organonitrogen compound GO:0010243 75 0.041
actin filament based process GO:0030029 220 0.040
tissue death GO:0016271 102 0.040
regulation of nervous system development GO:0051960 248 0.040
death GO:0016265 284 0.038
rho protein signal transduction GO:0007266 14 0.038
regulation of cell morphogenesis GO:0022604 163 0.038
epithelial cell migration GO:0010631 148 0.037
eye photoreceptor cell fate commitment GO:0042706 37 0.037
gland morphogenesis GO:0022612 145 0.036
small gtpase mediated signal transduction GO:0007264 88 0.036
cellular amine metabolic process GO:0044106 12 0.035
macromolecular complex assembly GO:0065003 256 0.035
open tracheal system development GO:0007424 204 0.035
regulation of protein catabolic process GO:0042176 55 0.035
developmental pigmentation GO:0048066 68 0.035
regulation of anatomical structure morphogenesis GO:0022603 242 0.035
eye development GO:0001654 323 0.034
protein phosphorylation GO:0006468 169 0.034
Human
salivary gland morphogenesis GO:0007435 145 0.034
regulation of phosphorylation GO:0042325 147 0.034
cell division GO:0051301 248 0.034
eye morphogenesis GO:0048592 260 0.034
cellular component assembly involved in morphogenesis GO:0010927 151 0.033
response to nitrogen compound GO:1901698 90 0.033
regulation of neurogenesis GO:0050767 158 0.033
regulation of nucleotide catabolic process GO:0030811 48 0.033
positive regulation of nucleobase containing compound metabolic process GO:0045935 332 0.032
Human
positive regulation of rho gtpase activity GO:0032321 19 0.032
cell projection assembly GO:0030031 94 0.032
response to organic substance GO:0010033 284 0.031
negative regulation of catalytic activity GO:0043086 42 0.031
tissue migration GO:0090130 155 0.031
organophosphate metabolic process GO:0019637 195 0.030
r7 cell differentiation GO:0045466 43 0.030
regulation of anatomical structure size GO:0090066 163 0.030
regulation of erbb signaling pathway GO:1901184 42 0.029
regulation of multicellular organismal development GO:2000026 414 0.029
response to endogenous stimulus GO:0009719 119 0.029
organonitrogen compound catabolic process GO:1901565 128 0.029
ovarian follicle cell migration GO:0007297 121 0.029
regulation of neuron projection development GO:0010975 69 0.029
regulation of ras gtpase activity GO:0032318 38 0.028
organic substance catabolic process GO:1901575 308 0.028
regulation of localization GO:0032879 275 0.028
macromolecule catabolic process GO:0009057 161 0.028
phosphatidylinositol mediated signaling GO:0048015 4 0.028
negative regulation of nitrogen compound metabolic process GO:0051172 265 0.028
negative regulation of developmental process GO:0051093 201 0.028
small molecule metabolic process GO:0044281 305 0.028
negative regulation of multicellular organismal process GO:0051241 142 0.027
nuclear division GO:0000280 332 0.027
positive regulation of nucleoside metabolic process GO:0045979 47 0.027
regulation of neuron differentiation GO:0045664 103 0.027
single organism catabolic process GO:0044712 228 0.027
protein transport GO:0015031 155 0.027
dephosphorylation GO:0016311 51 0.027
positive regulation of developmental process GO:0051094 143 0.026
stem cell differentiation GO:0048863 117 0.026
reproductive structure development GO:0048608 74 0.026
regulation of gtp catabolic process GO:0033124 44 0.026
cell death GO:0008219 279 0.026
intracellular protein transport GO:0006886 104 0.025
regulation of cell shape GO:0008360 113 0.025
mitotic nuclear division GO:0007067 213 0.025
negative regulation of molecular function GO:0044092 51 0.025
Human
peptidyl tyrosine modification GO:0018212 24 0.025
cellular amino acid metabolic process GO:0006520 61 0.025
neurological system process GO:0050877 358 0.025
synaptic transmission GO:0007268 288 0.025
endocytosis GO:0006897 310 0.025
eggshell formation GO:0030703 105 0.024
axon development GO:0061564 297 0.024
cognition GO:0050890 141 0.024
regulation of mapk cascade GO:0043408 92 0.024
organic substance transport GO:0071702 257 0.024
proteasome mediated ubiquitin dependent protein catabolic process GO:0043161 54 0.024
response to oxygen containing compound GO:1901700 200 0.023
regulation of immune system process GO:0002682 176 0.023
transmembrane receptor protein tyrosine kinase signaling pathway GO:0007169 116 0.023
ribose phosphate metabolic process GO:0019693 145 0.023
inter male aggressive behavior GO:0002121 60 0.023
regulation of small gtpase mediated signal transduction GO:0051056 93 0.023
cellular macromolecule localization GO:0070727 220 0.023
Human
photoreceptor cell differentiation GO:0046530 170 0.023
forebrain development GO:0030900 2 0.023
regulation of proteasomal ubiquitin dependent protein catabolic process GO:0032434 37 0.022
positive regulation of signal transduction GO:0009967 223 0.022
Human
pigmentation GO:0043473 75 0.022
heterocycle catabolic process GO:0046700 166 0.022
cellular lipid metabolic process GO:0044255 83 0.022
establishment or maintenance of cell polarity GO:0007163 167 0.022
embryonic development via the syncytial blastoderm GO:0001700 148 0.022
eye photoreceptor cell differentiation GO:0001754 145 0.022
positive regulation of nucleic acid templated transcription GO:1903508 266 0.022
Human
homeostatic process GO:0042592 199 0.022
Human
nucleoside triphosphate metabolic process GO:0009141 120 0.021
single organism biosynthetic process GO:0044711 206 0.021
Human
neuron projection guidance GO:0097485 241 0.021
mating GO:0007618 120 0.021
telencephalon development GO:0021537 2 0.021
germarium derived egg chamber formation GO:0007293 101 0.021
positive regulation of cell differentiation GO:0045597 64 0.020
compound eye photoreceptor fate commitment GO:0001752 36 0.020
histolysis GO:0007559 102 0.020
positive regulation of hydrolase activity GO:0051345 78 0.020
positive regulation of purine nucleotide catabolic process GO:0033123 46 0.020
regulation of cell fate commitment GO:0010453 29 0.020
regulation of proteolysis GO:0030162 87 0.020
leg disc morphogenesis GO:0007478 80 0.020
peptidyl lysine modification GO:0018205 57 0.020
imaginal disc pattern formation GO:0007447 91 0.020
imaginal disc derived leg morphogenesis GO:0007480 80 0.020
ribonucleoside metabolic process GO:0009119 127 0.020
organelle fission GO:0048285 340 0.020
regulation of hydrolase activity GO:0051336 97 0.019
establishment of localization in cell GO:0051649 402 0.019
positive regulation of phosphorus metabolic process GO:0010562 139 0.019
chemotaxis GO:0006935 249 0.019
stem cell development GO:0048864 79 0.019
aggressive behavior GO:0002118 63 0.019
positive regulation of biosynthetic process GO:0009891 316 0.019
Human
determination of adult lifespan GO:0008340 137 0.019
actin filament organization GO:0007015 126 0.019
autophagy GO:0006914 108 0.019
proteolysis GO:0006508 192 0.019
transcription from rna polymerase ii promoter GO:0006366 368 0.019
Human
negative regulation of phosphate metabolic process GO:0045936 45 0.019
lateral inhibition GO:0046331 206 0.019
regulation of cell morphogenesis involved in differentiation GO:0010769 61 0.019
regulation of proteolysis involved in cellular protein catabolic process GO:1903050 44 0.018
positive regulation of nucleotide catabolic process GO:0030813 46 0.018
regulation of axonogenesis GO:0050770 32 0.018
organophosphate catabolic process GO:0046434 112 0.018
regulation of rho gtpase activity GO:0032319 20 0.018
purine ribonucleoside triphosphate catabolic process GO:0009207 108 0.018
purine ribonucleoside triphosphate metabolic process GO:0009205 119 0.018
protein maturation GO:0051604 71 0.018
inositol lipid mediated signaling GO:0048017 4 0.018
brain development GO:0007420 120 0.017
regulation of protein phosphorylation GO:0001932 64 0.017
learning or memory GO:0007611 141 0.017
tor signaling GO:0031929 32 0.017
negative regulation of cell development GO:0010721 62 0.017
regulation of translation GO:0006417 56 0.017
negative regulation of phosphorus metabolic process GO:0010563 45 0.017
regulation of gtpase activity GO:0043087 44 0.017
positive regulation of cell communication GO:0010647 250 0.017
Human
ion transport GO:0006811 145 0.017
ribonucleotide catabolic process GO:0009261 109 0.017
nucleoside triphosphate catabolic process GO:0009143 108 0.017
peptidyl amino acid modification GO:0018193 105 0.017
Human
nucleotide catabolic process GO:0009166 109 0.017
positive regulation of purine nucleotide metabolic process GO:1900544 55 0.017
maintenance of location GO:0051235 73 0.017
positive regulation of signaling GO:0023056 243 0.017
Human
rna localization GO:0006403 115 0.017
regulation of nuclear division GO:0051783 58 0.017
positive regulation of proteolysis GO:0045862 52 0.017
regulation of organelle organization GO:0033043 196 0.017
Human
monocarboxylic acid transport GO:0015718 3 0.017
positive regulation of ras gtpase activity GO:0032320 36 0.017
dendrite morphogenesis GO:0048813 199 0.017
nucleoside phosphate metabolic process GO:0006753 162 0.017
regulation of microtubule polymerization or depolymerization GO:0031110 27 0.017
nucleoside metabolic process GO:0009116 127 0.017
compound eye photoreceptor cell differentiation GO:0001751 140 0.016
cellular protein complex assembly GO:0043623 71 0.016
single organismal cell cell adhesion GO:0016337 45 0.016
nucleoside phosphate catabolic process GO:1901292 110 0.016
negative regulation of neurogenesis GO:0050768 53 0.016
immune response regulating signaling pathway GO:0002764 2 0.016
purine ribonucleotide metabolic process GO:0009150 145 0.016
cell cell signaling involved in cell fate commitment GO:0045168 210 0.016
salivary gland histolysis GO:0035070 88 0.016
purine ribonucleoside metabolic process GO:0046128 127 0.016
purine ribonucleoside catabolic process GO:0046130 112 0.016
autophagic cell death GO:0048102 83 0.016
regulation of cell cycle process GO:0010564 181 0.016
regulation of nucleotide metabolic process GO:0006140 62 0.016
peptidyl tyrosine phosphorylation GO:0018108 24 0.016
negative regulation of rna metabolic process GO:0051253 251 0.016
cell adhesion GO:0007155 136 0.016
positive regulation of cellular component biogenesis GO:0044089 80 0.016
cellular macromolecule catabolic process GO:0044265 136 0.015
head development GO:0060322 135 0.015
regulation of cytoskeleton organization GO:0051493 89 0.015
cellular response to organonitrogen compound GO:0071417 36 0.015
regulation of peptidyl tyrosine phosphorylation GO:0050730 10 0.015
torc1 signaling GO:0038202 12 0.015
negative regulation of cellular component organization GO:0051129 108 0.015
cellular response to endogenous stimulus GO:0071495 80 0.015
positive regulation of nucleotide metabolic process GO:0045981 55 0.015
purine ribonucleotide catabolic process GO:0009154 109 0.015
protein complex assembly GO:0006461 200 0.015
negative regulation of protein phosphorylation GO:0001933 17 0.015
lipid storage GO:0019915 38 0.015
secretion by cell GO:0032940 101 0.015
taxis GO:0042330 304 0.015
positive regulation of catalytic activity GO:0043085 118 0.015
morphogenesis of embryonic epithelium GO:0016331 94 0.015
regulation of autophagy GO:0010506 62 0.015
locomotory behavior GO:0007626 176 0.014
posttranscriptional regulation of gene expression GO:0010608 145 0.014
positive regulation of gtp catabolic process GO:0033126 43 0.014
regulation of mitotic cell cycle GO:0007346 190 0.014
positive regulation of cellular component organization GO:0051130 156 0.014
Human
chorion containing eggshell formation GO:0007304 105 0.014
secretion GO:0046903 109 0.014
negative regulation of gene expression GO:0010629 387 0.014
ribonucleotide metabolic process GO:0009259 145 0.014
tube morphogenesis GO:0035239 191 0.014
response to external biotic stimulus GO:0043207 293 0.014
intracellular signal transduction GO:0035556 300 0.014
kidney development GO:0001822 3 0.014
digestive tract morphogenesis GO:0048546 127 0.014
circulatory system development GO:0072359 82 0.014
nucleobase containing compound catabolic process GO:0034655 165 0.014
multi organism behavior GO:0051705 175 0.014
positive regulation of transport GO:0051050 92 0.014
regulation of cell differentiation GO:0045595 302 0.014
sex differentiation GO:0007548 81 0.013
positive regulation of cell migration GO:0030335 2 0.013
adult behavior GO:0030534 137 0.013
protein processing GO:0016485 68 0.013
hematopoietic or lymphoid organ development GO:0048534 57 0.013
regulation of cellular component size GO:0032535 98 0.013
regulation of proteasomal protein catabolic process GO:0061136 39 0.013
nucleoside catabolic process GO:0009164 112 0.013
respiratory system development GO:0060541 213 0.013
reproductive system development GO:0061458 74 0.013
positive regulation of phosphate metabolic process GO:0045937 139 0.013
cellular response to nitrogen compound GO:1901699 51 0.013
modification dependent protein catabolic process GO:0019941 78 0.013
regulation of intracellular signal transduction GO:1902531 236 0.013
ribonucleoside triphosphate catabolic process GO:0009203 108 0.013
positive regulation of rna biosynthetic process GO:1902680 266 0.013
Human
positive regulation of cellular biosynthetic process GO:0031328 316 0.013
Human
positive regulation of peptidyl tyrosine phosphorylation GO:0050731 4 0.013
nucleotide metabolic process GO:0009117 161 0.013
carbohydrate derivative catabolic process GO:1901136 118 0.013
vesicle mediated transport GO:0016192 381 0.013
positive regulation of gtpase activity GO:0043547 43 0.013
ubiquitin dependent protein catabolic process GO:0006511 78 0.013
aromatic compound catabolic process GO:0019439 166 0.013
regulation of chromosome organization GO:0033044 64 0.013
Human
embryo development ending in birth or egg hatching GO:0009792 152 0.012
mesenchymal cell differentiation GO:0048762 1 0.012
protein modification by small protein conjugation GO:0032446 79 0.012
Human
embryonic axis specification GO:0000578 107 0.012
somatic muscle development GO:0007525 66 0.012
organic cyclic compound catabolic process GO:1901361 168 0.012
anterior posterior axis specification GO:0009948 109 0.012
regulation of embryonic development GO:0045995 68 0.012
salivary gland cell autophagic cell death GO:0035071 83 0.012
oocyte construction GO:0007308 112 0.012
positive regulation of molecular function GO:0044093 136 0.012
positive regulation of nitrogen compound metabolic process GO:0051173 354 0.012
Human
camera type eye development GO:0043010 4 0.012
regulation of purine nucleotide metabolic process GO:1900542 62 0.012
metal ion transport GO:0030001 74 0.012
regulation of cellular protein catabolic process GO:1903362 44 0.012
regulation of neuron death GO:1901214 26 0.012
epidermal growth factor receptor signaling pathway GO:0007173 58 0.012
regulation of cell substrate adhesion GO:0010810 2 0.012
chromatin organization GO:0006325 207 0.012
photoreceptor cell development GO:0042461 96 0.012
response to other organism GO:0051707 293 0.012
chromosome organization GO:0051276 360 0.012
Human
positive regulation of cell motility GO:2000147 3 0.012
negative regulation of protein metabolic process GO:0051248 85 0.012
tube development GO:0035295 244 0.012
positive regulation of proteasomal protein catabolic process GO:1901800 20 0.012
phagocytosis GO:0006909 215 0.012
tissue homeostasis GO:0001894 36 0.012
mushroom body development GO:0016319 70 0.012
lipid metabolic process GO:0006629 121 0.011
blastoderm segmentation GO:0007350 159 0.011
regulation of transmembrane receptor protein serine threonine kinase signaling pathway GO:0090092 38 0.011
connective tissue development GO:0061448 3 0.011
oocyte microtubule cytoskeleton organization GO:0016325 35 0.011
mitotic sister chromatid segregation GO:0000070 87 0.011
negative regulation of signaling GO:0023057 219 0.011
purine nucleoside catabolic process GO:0006152 112 0.011
multi multicellular organism process GO:0044706 123 0.011
epithelial tube morphogenesis GO:0060562 88 0.011
leg disc development GO:0035218 92 0.011
stress activated protein kinase signaling cascade GO:0031098 55 0.011
regulation of cellular localization GO:0060341 136 0.011
nitrogen compound transport GO:0071705 85 0.011
cellular nitrogen compound catabolic process GO:0044270 165 0.011
dendrite development GO:0016358 204 0.011
positive regulation of phosphorylation GO:0042327 87 0.011
gtp catabolic process GO:0006184 72 0.011
regulation of protein kinase activity GO:0045859 51 0.011
response to abiotic stimulus GO:0009628 341 0.011
single organism behavior GO:0044708 391 0.011
eye pigmentation GO:0048069 43 0.011
cellular response to chemical stimulus GO:0070887 199 0.011
dorsal closure GO:0007391 79 0.011
negative regulation of signal transduction GO:0009968 206 0.011
ribonucleoside triphosphate metabolic process GO:0009199 119 0.011
positive regulation of protein catabolic process GO:0045732 34 0.011
regulation of phosphatidylinositol 3 kinase signaling GO:0014066 4 0.011
gtp metabolic process GO:0046039 72 0.010
photoreceptor cell fate commitment GO:0046552 41 0.010
hematopoietic progenitor cell differentiation GO:0002244 1 0.010
carbohydrate derivative metabolic process GO:1901135 217 0.010
nucleobase containing small molecule metabolic process GO:0055086 174 0.010
protein catabolic process GO:0030163 101 0.010
positive regulation of cellular protein metabolic process GO:0032270 118 0.010
regulation of actin cytoskeleton organization GO:0032956 42 0.010
compound eye morphogenesis GO:0001745 249 0.010
immune response activating signal transduction GO:0002757 2 0.010
purine nucleoside triphosphate catabolic process GO:0009146 108 0.010
negative regulation of cellular protein metabolic process GO:0032269 85 0.010
regulation of rna splicing GO:0043484 69 0.010
developmental programmed cell death GO:0010623 138 0.010

tankyrase disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in fly and predicted with the fly functional network.

Disease DO term ID Size Probability Func Analog Org
disease of anatomical entity DOID:7 0 0.020
nervous system disease DOID:863 0 0.011
musculoskeletal system disease DOID:17 0 0.010