Drosophila melanogaster

57 known processes

squ (Dmel_CG4711)

squash

(Aliases: mat(2)cellHK35,CG4711,Dmel\CG4711,mat(2)cell-A)

squ biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
cellularization GO:0007349 90 0.652
oocyte differentiation GO:0009994 145 0.471
oocyte construction GO:0007308 112 0.464
regulation of cell development GO:0060284 215 0.423
oocyte axis specification GO:0007309 108 0.383
karyosome formation GO:0030717 22 0.344
organelle fission GO:0048285 340 0.307
establishment of localization in cell GO:0051649 402 0.261
axis specification GO:0009798 167 0.255
regulation of multicellular organismal development GO:2000026 414 0.254
regulation of transcription from rna polymerase ii promoter GO:0006357 378 0.245
oocyte development GO:0048599 124 0.221
regulation of cellular component biogenesis GO:0044087 201 0.211
regulation of pole plasm oskar mrna localization GO:0007317 27 0.193
actin cytoskeleton organization GO:0030036 206 0.179
meiotic cell cycle process GO:1903046 132 0.163
regulation of cellular protein metabolic process GO:0032268 243 0.161
germarium derived egg chamber formation GO:0007293 101 0.149
microtubule organizing center organization GO:0031023 168 0.146
regulation of embryonic pattern specification GO:1902875 27 0.144
organelle assembly GO:0070925 198 0.142
negative regulation of biosynthetic process GO:0009890 277 0.139
nuclear division GO:0000280 332 0.136
oocyte anterior posterior axis specification GO:0007314 72 0.130
cellular catabolic process GO:0044248 372 0.128
positive regulation of nucleic acid templated transcription GO:1903508 266 0.127
transcription from rna polymerase ii promoter GO:0006366 368 0.121
chromosome organization GO:0051276 360 0.118
determination of adult lifespan GO:0008340 137 0.116
negative regulation of cellular macromolecule biosynthetic process GO:2000113 267 0.109
multicellular organismal aging GO:0010259 140 0.108
regulation of developmental growth GO:0048638 174 0.103
positive regulation of macromolecule metabolic process GO:0010604 405 0.095
negative regulation of rna biosynthetic process GO:1902679 240 0.091
negative regulation of macromolecule biosynthetic process GO:0010558 270 0.090
developmental maturation GO:0021700 172 0.090
organelle localization GO:0051640 148 0.090
spindle organization GO:0007051 253 0.086
germarium derived oocyte fate determination GO:0007294 26 0.085
negative regulation of rna metabolic process GO:0051253 251 0.085
organic substance catabolic process GO:1901575 308 0.083
regulation of localization GO:0032879 275 0.083
positive regulation of response to stimulus GO:0048584 323 0.082
nucleus localization GO:0051647 34 0.082
macromolecule catabolic process GO:0009057 161 0.081
body morphogenesis GO:0010171 2 0.080
establishment of nucleus localization GO:0040023 26 0.079
cell cycle phase transition GO:0044770 140 0.078
protein complex biogenesis GO:0070271 201 0.077
positive regulation of signal transduction GO:0009967 223 0.077
oocyte microtubule cytoskeleton organization GO:0016325 35 0.077
tube morphogenesis GO:0035239 191 0.076
positive regulation of gene expression GO:0010628 290 0.076
mitotic cell cycle phase transition GO:0044772 138 0.074
regulation of cell differentiation GO:0045595 302 0.074
positive regulation of catalytic activity GO:0043085 118 0.074
regulation of epithelial cell proliferation GO:0050678 4 0.072
negative regulation of gene expression GO:0010629 387 0.070
catabolic process GO:0009056 409 0.070
establishment or maintenance of microtubule cytoskeleton polarity GO:0030951 41 0.069
positive regulation of cell communication GO:0010647 250 0.068
positive regulation of biosynthetic process GO:0009891 316 0.066
positive regulation of nitrogen compound metabolic process GO:0051173 354 0.066
anterior posterior axis specification GO:0009948 109 0.065
positive regulation of macromolecule biosynthetic process GO:0010557 283 0.064
negative regulation of cellular biosynthetic process GO:0031327 277 0.063
negative regulation of nucleobase containing compound metabolic process GO:0045934 261 0.062
regulation of oocyte development GO:0060281 27 0.062
regulation of transport GO:0051049 181 0.061
germarium derived oocyte differentiation GO:0030706 29 0.060
female meiotic division GO:0007143 70 0.060
endocytosis GO:0006897 310 0.058
positive regulation of cellular biosynthetic process GO:0031328 316 0.058
negative regulation of transposition GO:0010529 12 0.058
oocyte nucleus localization involved in oocyte dorsal ventral axis specification GO:0051663 12 0.058
actin filament based process GO:0030029 220 0.055
cell maturation GO:0048469 144 0.055
regulation of protein metabolic process GO:0051246 256 0.055
regulation of mitotic cell cycle GO:0007346 190 0.054
acylglycerol catabolic process GO:0046464 3 0.054
regulation of catabolic process GO:0009894 170 0.053
embryonic pattern specification GO:0009880 174 0.053
negative regulation of developmental process GO:0051093 201 0.052
macromolecular complex assembly GO:0065003 256 0.052
establishment of organelle localization GO:0051656 122 0.051
intracellular signal transduction GO:0035556 300 0.051
protein modification by small protein conjugation or removal GO:0070647 106 0.050
asymmetric cell division GO:0008356 37 0.049
negative regulation of transcription from rna polymerase ii promoter GO:0000122 119 0.048
mitotic nuclear division GO:0007067 213 0.047
pole plasm rna localization GO:0007316 52 0.047
anterior posterior pattern specification GO:0009952 136 0.047
positive regulation of rna metabolic process GO:0051254 271 0.046
positive regulation of multicellular organismal process GO:0051240 143 0.046
regulation of nervous system development GO:0051960 248 0.045
positive regulation of transcription from rna polymerase ii promoter GO:0045944 204 0.045
peripheral nervous system development GO:0007422 52 0.044
cellular macromolecule catabolic process GO:0044265 136 0.043
aging GO:0007568 143 0.043
regulation of cell cycle phase transition GO:1901987 130 0.043
tube development GO:0035295 244 0.043
developmental growth GO:0048589 280 0.042
maternal determination of anterior posterior axis embryo GO:0008358 74 0.042
embryonic development via the syncytial blastoderm GO:0001700 148 0.042
response to radiation GO:0009314 155 0.042
negative regulation of cellular metabolic process GO:0031324 382 0.042
regulation of cell cycle process GO:0010564 181 0.042
meiotic nuclear division GO:0007126 151 0.041
single organism intracellular transport GO:1902582 207 0.040
negative regulation of multicellular organismal process GO:0051241 142 0.040
nuclear migration GO:0007097 20 0.039
digestive tract morphogenesis GO:0048546 127 0.039
regulation of synapse assembly GO:0051963 94 0.038
regulation of phosphate metabolic process GO:0019220 210 0.038
homeostatic process GO:0042592 199 0.038
response to light stimulus GO:0009416 124 0.038
positive regulation of developmental process GO:0051094 143 0.038
positive regulation of cellular component organization GO:0051130 156 0.038
regulation of phosphorus metabolic process GO:0051174 210 0.038
regulation of cellular localization GO:0060341 136 0.038
regulation of embryonic development GO:0045995 68 0.037
cellular macromolecule localization GO:0070727 220 0.037
phosphorylation GO:0016310 294 0.037
positive regulation of rna biosynthetic process GO:1902680 266 0.035
dorsal ventral axis specification GO:0009950 66 0.034
localization of cell GO:0051674 257 0.034
regulation of neurogenesis GO:0050767 158 0.033
pirna metabolic process GO:0034587 10 0.033
regulation of catalytic activity GO:0050790 185 0.033
embryonic morphogenesis GO:0048598 206 0.032
negative regulation of signaling GO:0023057 219 0.032
protein complex assembly GO:0006461 200 0.032
positive regulation of molecular function GO:0044093 136 0.032
small gtpase mediated signal transduction GO:0007264 88 0.032
establishment or maintenance of cytoskeleton polarity GO:0030952 44 0.031
positive regulation of cellular component biogenesis GO:0044089 80 0.031
proteolysis GO:0006508 192 0.031
nucleus organization GO:0006997 45 0.031
signal transduction by phosphorylation GO:0023014 107 0.030
adult behavior GO:0030534 137 0.030
negative regulation of nucleic acid templated transcription GO:1903507 240 0.030
regulation of cellular catabolic process GO:0031329 157 0.030
programmed cell death GO:0012501 257 0.030
cellular amide metabolic process GO:0043603 80 0.030
regulation of protein complex assembly GO:0043254 42 0.030
digestive tract development GO:0048565 149 0.030
response to organic substance GO:0010033 284 0.030
protein ubiquitination GO:0016567 70 0.030
meiotic cell cycle GO:0051321 171 0.029
response to uv GO:0009411 24 0.029
positive regulation of phosphate metabolic process GO:0045937 139 0.029
cellular protein catabolic process GO:0044257 83 0.029
regulation of molecular function GO:0065009 217 0.029
positive regulation of protein metabolic process GO:0051247 128 0.029
aromatic compound catabolic process GO:0019439 166 0.028
regulation of growth GO:0040008 233 0.028
death GO:0016265 284 0.028
peptidyl threonine phosphorylation GO:0018107 2 0.028
modification dependent macromolecule catabolic process GO:0043632 79 0.027
regulation of reproductive process GO:2000241 54 0.027
positive regulation of phosphorus metabolic process GO:0010562 139 0.027
actomyosin structure organization GO:0031032 56 0.026
proteolysis involved in cellular protein catabolic process GO:0051603 83 0.026
regulation of apoptotic process GO:0042981 130 0.026
protein k48 linked ubiquitination GO:0070936 3 0.026
oocyte localization involved in germarium derived egg chamber formation GO:0030720 12 0.026
oocyte dorsal ventral axis specification GO:0007310 34 0.025
regulation of protein localization GO:0032880 76 0.025
negative regulation of transcription dna templated GO:0045892 237 0.025
establishment or maintenance of cell polarity GO:0007163 167 0.025
defense response to other organism GO:0098542 225 0.025
positive regulation of hydrolase activity GO:0051345 78 0.025
pole plasm assembly GO:0007315 61 0.025
positive regulation of nucleobase containing compound metabolic process GO:0045935 332 0.025
positive regulation of transcription dna templated GO:0045893 266 0.024
response to abiotic stimulus GO:0009628 341 0.024
cellular protein modification process GO:0006464 438 0.024
organonitrogen compound metabolic process GO:1901564 318 0.024
translation GO:0006412 69 0.024
positive regulation of catabolic process GO:0009896 105 0.024
ubiquitin dependent protein catabolic process GO:0006511 78 0.024
metal ion transport GO:0030001 74 0.023
positive regulation of mitotic cell cycle GO:0045931 34 0.023
ribonucleoprotein complex subunit organization GO:0071826 28 0.023
head development GO:0060322 135 0.023
cell projection assembly GO:0030031 94 0.023
regulation of cytoskeleton organization GO:0051493 89 0.023
regulation of response to stress GO:0080134 200 0.023
vesicle mediated transport GO:0016192 381 0.023
negative regulation of protein metabolic process GO:0051248 85 0.022
regulation of cell cycle GO:0051726 291 0.022
regulation of response to external stimulus GO:0032101 115 0.022
protein modification process GO:0036211 438 0.022
negative regulation of cellular protein metabolic process GO:0032269 85 0.022
g2 dna damage checkpoint GO:0031572 69 0.022
response to oxygen containing compound GO:1901700 200 0.022
positive regulation of cellular catabolic process GO:0031331 95 0.022
protein processing GO:0016485 68 0.022
regulation of cell maturation GO:1903429 27 0.022
protein catabolic process GO:0030163 101 0.022
negative regulation of cell death GO:0060548 81 0.022
central nervous system development GO:0007417 201 0.021
negative regulation of cytoskeleton organization GO:0051494 30 0.021
mitotic spindle organization GO:0007052 220 0.021
digestive system development GO:0055123 149 0.021
cell death GO:0008219 279 0.020
nuclear transcribed mrna catabolic process GO:0000956 24 0.020
membrane organization GO:0061024 112 0.020
modification dependent protein catabolic process GO:0019941 78 0.020
ion transport GO:0006811 145 0.020
positive regulation of cell proliferation GO:0008284 47 0.020
embryo development ending in birth or egg hatching GO:0009792 152 0.019
cellular macromolecular complex assembly GO:0034622 153 0.019
response to biotic stimulus GO:0009607 294 0.019
positive regulation of nucleocytoplasmic transport GO:0046824 24 0.019
secretion by cell GO:0032940 101 0.019
positive regulation of lipid catabolic process GO:0050996 1 0.019
glial cell differentiation GO:0010001 35 0.019
regulation of cell proliferation GO:0042127 163 0.019
ion transmembrane transport GO:0034220 122 0.019
regulation of immune system process GO:0002682 176 0.019
regulation of protein polymerization GO:0032271 28 0.019
regulation of cyclin dependent protein serine threonine kinase activity GO:0000079 3 0.019
nucleobase containing compound catabolic process GO:0034655 165 0.019
male gamete generation GO:0048232 201 0.018
blood circulation GO:0008015 26 0.018
intracellular mrna localization involved in anterior posterior axis specification GO:0060811 53 0.018
mapk cascade GO:0000165 107 0.018
negative regulation of cell communication GO:0010648 223 0.018
response to other organism GO:0051707 293 0.018
gliogenesis GO:0042063 80 0.018
intracellular transport GO:0046907 228 0.017
regulation of multi organism process GO:0043900 131 0.017
stem cell division GO:0017145 69 0.017
segmentation GO:0035282 207 0.017
regulation of anatomical structure morphogenesis GO:0022603 242 0.017
ras protein signal transduction GO:0007265 88 0.017
oocyte microtubule cytoskeleton polarization GO:0008103 22 0.017
single organism cellular localization GO:1902580 180 0.017
innate immune response GO:0045087 144 0.017
defense response GO:0006952 300 0.017
regulation of mapk cascade GO:0043408 92 0.017
single organism carbohydrate metabolic process GO:0044723 72 0.017
reproductive structure development GO:0048608 74 0.017
chromatin modification GO:0016568 147 0.017
embryonic axis specification GO:0000578 107 0.016
positive regulation of protein transport GO:0051222 37 0.016
regulation of nucleocytoplasmic transport GO:0046822 35 0.016
asymmetric stem cell division GO:0098722 49 0.016
positive regulation of transport GO:0051050 92 0.016
cellular response to dna damage stimulus GO:0006974 223 0.016
chromatin organization GO:0006325 207 0.016
regulation of cell death GO:0010941 173 0.016
regulation of intracellular signal transduction GO:1902531 236 0.016
regulation of protein transport GO:0051223 57 0.016
blastoderm segmentation GO:0007350 159 0.016
single organism biosynthetic process GO:0044711 206 0.016
response to bacterium GO:0009617 198 0.015
establishment of oocyte nucleus localization involved in oocyte dorsal ventral axis specification GO:0030722 6 0.015
regulation of programmed cell death GO:0043067 152 0.015
protein modification by small protein conjugation GO:0032446 79 0.015
eye antennal disc development GO:0035214 60 0.015
regulation of ras protein signal transduction GO:0046578 93 0.015
organic substance transport GO:0071702 257 0.015
intracellular protein transport GO:0006886 104 0.015
negative regulation of transmembrane receptor protein serine threonine kinase signaling pathway GO:0090101 18 0.015
limb morphogenesis GO:0035108 1 0.015
positive regulation of signaling GO:0023056 243 0.015
immune response GO:0006955 246 0.014
glycerolipid catabolic process GO:0046503 3 0.014
regulation of intracellular protein transport GO:0033157 46 0.014
tripartite regional subdivision GO:0007351 103 0.014
cellular nitrogen compound catabolic process GO:0044270 165 0.014
pronuclear migration GO:0035046 4 0.014
positive regulation of nervous system development GO:0051962 69 0.014
cell motility GO:0048870 251 0.014
response to wounding GO:0009611 94 0.014
small molecule metabolic process GO:0044281 305 0.014
response to endogenous stimulus GO:0009719 119 0.014
ribonucleoprotein complex assembly GO:0022618 23 0.014
single organism membrane organization GO:0044802 93 0.014
protein localization GO:0008104 284 0.014
regulation of mitotic cell cycle phase transition GO:1901990 130 0.014
regulation of translation GO:0006417 56 0.014
dendrite morphogenesis GO:0048813 199 0.014
intracellular mrna localization GO:0008298 66 0.014
positive regulation of lipid metabolic process GO:0045834 4 0.013
negative regulation of cellular component organization GO:0051129 108 0.013
regulation of phosphorylation GO:0042325 147 0.013
stem cell development GO:0048864 79 0.013
negative regulation of mitotic cell cycle GO:0045930 109 0.013
regulation of proteolysis GO:0030162 87 0.013
cytoplasm organization GO:0007028 64 0.013
carboxylic acid metabolic process GO:0019752 92 0.013
pole plasm oskar mrna localization GO:0045451 46 0.013
negative regulation of programmed cell death GO:0043069 72 0.013
ribonucleotide metabolic process GO:0009259 145 0.013
gene silencing by rna GO:0031047 57 0.013
glutamate metabolic process GO:0006536 5 0.013
peptidyl threonine modification GO:0018210 3 0.013
rna phosphodiester bond hydrolysis exonucleolytic GO:0090503 4 0.012
defense response to bacterium GO:0042742 178 0.012
oocyte fate determination GO:0030716 27 0.012
negative regulation of response to stimulus GO:0048585 258 0.012
pole plasm mrna localization GO:0019094 49 0.012
somatic stem cell division GO:0048103 37 0.012
compound eye development GO:0048749 307 0.012
dendrite development GO:0016358 204 0.012
negative regulation of epithelial cell proliferation GO:0050680 4 0.012
dna alkylation GO:0006305 4 0.012
regulation of mitotic cell cycle embryonic GO:0009794 11 0.012
positive regulation of cell cycle GO:0045787 43 0.012
secretion GO:0046903 109 0.012
protein transport GO:0015031 155 0.012
intracellular mrna localization involved in pattern specification process GO:0060810 56 0.012
regulation of protein ubiquitination GO:0031396 22 0.012
regulation of developmental pigmentation GO:0048070 24 0.012
positive regulation of purine nucleotide metabolic process GO:1900544 55 0.012
regulation of epidermal growth factor receptor signaling pathway GO:0042058 42 0.012
regulation of cell cell adhesion GO:0022407 21 0.012
mesenchymal cell development GO:0014031 1 0.011
sister chromatid segregation GO:0000819 92 0.011
proteasomal protein catabolic process GO:0010498 59 0.011
phagocytosis GO:0006909 215 0.011
feeding behavior GO:0007631 50 0.011
dorsal ventral pattern formation GO:0009953 133 0.011
positive regulation of transcription factor import into nucleus GO:0042993 19 0.011
positive regulation of purine nucleotide catabolic process GO:0033123 46 0.011
protein polymerization GO:0051258 42 0.011
establishment of cell polarity GO:0030010 40 0.011
pole plasm protein localization GO:0007318 10 0.011
regulation of establishment of protein localization GO:0070201 61 0.011
cell proliferation GO:0008283 299 0.011
regulation of cellular protein catabolic process GO:1903362 44 0.011
spindle assembly GO:0051225 80 0.011
regulation of purine nucleotide metabolic process GO:1900542 62 0.011
chromosome segregation GO:0007059 157 0.011
negative regulation of signal transduction GO:0009968 206 0.011
organic acid metabolic process GO:0006082 103 0.011
regulation of mitosis GO:0007088 56 0.011
positive regulation of phosphorylation GO:0042327 87 0.011
regulation of oskar mrna translation GO:0046011 8 0.011
establishment of glial blood brain barrier GO:0060857 14 0.011
cell cycle checkpoint GO:0000075 95 0.011
establishment of protein localization GO:0045184 163 0.011
single organism behavior GO:0044708 391 0.011
positive regulation of cellular amine metabolic process GO:0033240 0 0.011
spinal cord development GO:0021510 1 0.011
cellular response to chemical stimulus GO:0070887 199 0.010
synapse assembly GO:0007416 143 0.010
cytoplasmic transport GO:0016482 130 0.010
protein maturation GO:0051604 71 0.010
negative regulation of catabolic process GO:0009895 36 0.010
growth GO:0040007 359 0.010
regulation of protein modification process GO:0031399 112 0.010
locomotory behavior GO:0007626 176 0.010
fertilization GO:0009566 26 0.010
actin filament polymerization GO:0030041 27 0.010
anatomical structure homeostasis GO:0060249 97 0.010
activation of cysteine type endopeptidase activity involved in apoptotic process GO:0006919 16 0.010
regulation of hydrolase activity GO:0051336 97 0.010
organic cyclic compound catabolic process GO:1901361 168 0.010
regulation of synapse structure and activity GO:0050803 128 0.010
rna localization GO:0006403 115 0.010

squ disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in fly and predicted with the fly functional network.

Disease DO term ID Size Probability Func Analog Org
disease of anatomical entity DOID:7 0 0.082
cancer DOID:162 0 0.045
disease of cellular proliferation DOID:14566 0 0.045
organ system cancer DOID:0050686 0 0.023
large intestine cancer DOID:5672 0 0.011
gastrointestinal system cancer DOID:3119 0 0.011
intestinal cancer DOID:10155 0 0.011
colorectal cancer DOID:9256 0 0.011