Drosophila melanogaster

112 known processes

Mdr65 (Dmel_CG10181)

Multiple drug resistance 65

(Aliases: Dmel\CG10181,CG10181,mdr65,Mdr65A)

Mdr65 biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
eye development GO:0001654 323 0.128
response to abiotic stimulus GO:0009628 341 0.111
Rat Fly
response to heat GO:0009408 63 0.108
cation transport GO:0006812 110 0.069
Rat
appendage development GO:0048736 401 0.068
epithelial cell development GO:0002064 274 0.060
Rat
response to organic substance GO:0010033 284 0.054
kidney development GO:0001822 3 0.046
camera type eye development GO:0043010 4 0.045
neurological system process GO:0050877 358 0.042
localization of cell GO:0051674 257 0.042
Fly
growth GO:0040007 359 0.042
cellular response to ethanol GO:0071361 4 0.039
central nervous system development GO:0007417 201 0.038
Rat
developmental growth GO:0048589 280 0.038
vesicle mediated transport GO:0016192 381 0.037
response to radiation GO:0009314 155 0.037
Rat
endocytosis GO:0006897 310 0.036
ion transport GO:0006811 145 0.036
Rat
sensory organ morphogenesis GO:0090596 260 0.036
eye morphogenesis GO:0048592 260 0.035
cation transmembrane transport GO:0098655 88 0.034
catabolic process GO:0009056 409 0.033
l amino acid import GO:0043092 2 0.033
regulation of multicellular organismal development GO:2000026 414 0.033
forebrain development GO:0030900 2 0.032
appendage morphogenesis GO:0035107 397 0.031
synaptic transmission GO:0007268 288 0.031
single organism behavior GO:0044708 391 0.030
open tracheal system development GO:0007424 204 0.030
neuron projection guidance GO:0097485 241 0.030
compound eye development GO:0048749 307 0.030
body morphogenesis GO:0010171 2 0.030
organonitrogen compound metabolic process GO:1901564 318 0.029
tube development GO:0035295 244 0.029
imaginal disc derived appendage development GO:0048737 399 0.028
morphogenesis of an epithelium GO:0002009 276 0.027
organic acid metabolic process GO:0006082 103 0.027
response to oxygen containing compound GO:1901700 200 0.027
phagocytosis GO:0006909 215 0.027
positive regulation of gene expression GO:0010628 290 0.027
chemotaxis GO:0006935 249 0.027
axonogenesis GO:0007409 290 0.026
telencephalon development GO:0021537 2 0.026
cell motility GO:0048870 251 0.026
Fly
imaginal disc derived appendage morphogenesis GO:0035114 395 0.026
positive regulation of biosynthetic process GO:0009891 316 0.025
wing disc morphogenesis GO:0007472 344 0.025
imaginal disc derived wing morphogenesis GO:0007476 337 0.025
response to temperature stimulus GO:0009266 106 0.025
negative regulation of developmental process GO:0051093 201 0.025
single organism catabolic process GO:0044712 228 0.025
protein modification process GO:0036211 438 0.025
steroid catabolic process GO:0006706 1 0.025
regionalization GO:0003002 416 0.024
response to light stimulus GO:0009416 124 0.024
cellular component assembly involved in morphogenesis GO:0010927 151 0.024
extracellular structure organization GO:0043062 46 0.024
carboxylic acid metabolic process GO:0019752 92 0.024
regulation of localization GO:0032879 275 0.024
regulation of cell differentiation GO:0045595 302 0.024
cell migration GO:0016477 238 0.024
Fly
positive regulation of macromolecule metabolic process GO:0010604 405 0.024
epithelial tube morphogenesis GO:0060562 88 0.024
learning GO:0007612 75 0.023
oxoacid metabolic process GO:0043436 103 0.023
cellular protein modification process GO:0006464 438 0.023
negative regulation of cell development GO:0010721 62 0.023
regulation of cellular ketone metabolic process GO:0010565 3 0.023
eye photoreceptor cell differentiation GO:0001754 145 0.023
epithelial cell differentiation GO:0030855 322 0.023
Rat
lateral inhibition GO:0046331 206 0.023
tube morphogenesis GO:0035239 191 0.022
cellular amino acid metabolic process GO:0006520 61 0.022
columnar cuboidal epithelial cell differentiation GO:0002065 256 0.022
limb development GO:0060173 1 0.022
response to lipopolysaccharide GO:0032496 4 0.022
transmembrane transport GO:0055085 139 0.022
xenobiotic catabolic process GO:0042178 1 0.022
cognition GO:0050890 141 0.022
regulation of cellular component biogenesis GO:0044087 201 0.022
renal system development GO:0072001 72 0.022
organic substance catabolic process GO:1901575 308 0.021
axon guidance GO:0007411 233 0.021
learning or memory GO:0007611 141 0.021
camera type eye morphogenesis GO:0048593 2 0.021
cell proliferation GO:0008283 299 0.021
Human
cellular response to chemical stimulus GO:0070887 199 0.021
Rat
neuromuscular synaptic transmission GO:0007274 67 0.021
striated muscle cell differentiation GO:0051146 90 0.021
organic substance transport GO:0071702 257 0.021
Yeast Rat
cellular catabolic process GO:0044248 372 0.021
ion transmembrane transport GO:0034220 122 0.021
axon development GO:0061564 297 0.020
compound eye morphogenesis GO:0001745 249 0.020
respiratory system development GO:0060541 213 0.020
cell cell signaling involved in cell fate commitment GO:0045168 210 0.020
hormone catabolic process GO:0042447 3 0.020
small molecule metabolic process GO:0044281 305 0.020
post embryonic appendage morphogenesis GO:0035120 385 0.019
salivary gland development GO:0007431 162 0.019
gland morphogenesis GO:0022612 145 0.019
positive regulation of macromolecule biosynthetic process GO:0010557 283 0.019
death GO:0016265 284 0.019
Rat
estrogen metabolic process GO:0008210 1 0.019
gliogenesis GO:0042063 80 0.019
positive regulation of response to stimulus GO:0048584 323 0.019
Rat
nephron development GO:0072006 3 0.019
negative regulation of multicellular organismal process GO:0051241 142 0.019
salivary gland morphogenesis GO:0007435 145 0.019
regulation of growth GO:0040008 233 0.018
dendrite development GO:0016358 204 0.018
positive regulation of cellular biosynthetic process GO:0031328 316 0.018
developmental maturation GO:0021700 172 0.018
regulation of cell development GO:0060284 215 0.018
tissue morphogenesis GO:0048729 297 0.018
cuticle development GO:0042335 86 0.018
regulation of anatomical structure size GO:0090066 163 0.018
negative regulation of cell differentiation GO:0045596 143 0.018
response to nitrogen compound GO:1901698 90 0.017
negative regulation of cell communication GO:0010648 223 0.017
response to organophosphorus GO:0046683 2 0.017
hindbrain development GO:0030902 2 0.017
positive regulation of cell communication GO:0010647 250 0.017
regulation of cellular protein metabolic process GO:0032268 243 0.017
columnar cuboidal epithelial cell development GO:0002066 249 0.017
regulation of nervous system development GO:0051960 248 0.017
regulation of protein metabolic process GO:0051246 256 0.017
cellular ketone metabolic process GO:0042180 24 0.017
gland development GO:0048732 191 0.017
Rat
negative regulation of nitrogen compound metabolic process GO:0051172 265 0.017
histolysis GO:0007559 102 0.017
memory GO:0007613 94 0.017
protein complex biogenesis GO:0070271 201 0.017
developmental programmed cell death GO:0010623 138 0.016
taxis GO:0042330 304 0.016
connective tissue development GO:0061448 3 0.016
regulation of cellular amine metabolic process GO:0033238 3 0.016
establishment of localization in cell GO:0051649 402 0.016
neuron recognition GO:0008038 101 0.016
notch signaling pathway GO:0007219 120 0.016
negative regulation of response to stimulus GO:0048585 258 0.016
cellular response to organic substance GO:0071310 132 0.016
Rat
phosphorylation GO:0016310 294 0.016
acetylcholine metabolic process GO:0008291 2 0.016
locomotory behavior GO:0007626 176 0.015
neuromuscular junction development GO:0007528 149 0.015
multi organism behavior GO:0051705 175 0.015
skin development GO:0043588 65 0.015
axis specification GO:0009798 167 0.015
synapse organization GO:0050808 196 0.015
inter male aggressive behavior GO:0002121 60 0.015
segmentation GO:0035282 207 0.015
compound eye photoreceptor cell differentiation GO:0001751 140 0.015
photoreceptor cell differentiation GO:0046530 170 0.015
kidney epithelium development GO:0072073 3 0.015
ovarian follicle cell development GO:0030707 248 0.015
homeostatic process GO:0042592 199 0.015
macromolecule catabolic process GO:0009057 161 0.015
regulation of response to stress GO:0080134 200 0.014
negative regulation of signal transduction GO:0009968 206 0.014
regulation of cell morphogenesis GO:0022604 163 0.014
olfactory learning GO:0008355 56 0.014
g protein coupled receptor signaling pathway GO:0007186 136 0.014
regulation of neurogenesis GO:0050767 158 0.014
embryonic morphogenesis GO:0048598 206 0.014
exocrine system development GO:0035272 162 0.014
cell recognition GO:0008037 102 0.014
cell death GO:0008219 279 0.014
Rat
positive regulation of rna metabolic process GO:0051254 271 0.014
regulation of cellular amino acid metabolic process GO:0006521 0 0.014
single organism intracellular transport GO:1902582 207 0.014
positive regulation of rna biosynthetic process GO:1902680 266 0.014
neuropeptide signaling pathway GO:0007218 45 0.014
embryonic pattern specification GO:0009880 174 0.014
behavioral response to ethanol GO:0048149 49 0.014
photoreceptor cell development GO:0042461 96 0.014
regulation of cell proliferation GO:0042127 163 0.014
regulation of cell death GO:0010941 173 0.014
Rat
negative regulation of signaling GO:0023057 219 0.014
embryonic development via the syncytial blastoderm GO:0001700 148 0.014
positive regulation of signaling GO:0023056 243 0.014
blastoderm segmentation GO:0007350 159 0.014
response to glucose GO:0009749 2 0.014
negative regulation of gene expression GO:0010629 387 0.014
intracellular signal transduction GO:0035556 300 0.013
dendrite morphogenesis GO:0048813 199 0.013
response to ethanol GO:0045471 59 0.013
positive regulation of nucleobase containing compound metabolic process GO:0045935 332 0.013
aggressive behavior GO:0002118 63 0.013
spinal cord development GO:0021510 1 0.013
oocyte differentiation GO:0009994 145 0.013
retina development in camera type eye GO:0060041 4 0.013
regulation of developmental growth GO:0048638 174 0.013
acetate ester metabolic process GO:1900619 2 0.013
cellular macromolecular complex assembly GO:0034622 153 0.013
olfactory behavior GO:0042048 97 0.013
sulfur compound metabolic process GO:0006790 59 0.013
molting cycle chitin based cuticle GO:0007591 56 0.013
leg disc development GO:0035218 92 0.013
response to organic cyclic compound GO:0014070 89 0.013
protein localization GO:0008104 284 0.012
chorion containing eggshell formation GO:0007304 105 0.012
tripartite regional subdivision GO:0007351 103 0.012
heterocycle catabolic process GO:0046700 166 0.012
chemosensory behavior GO:0007635 106 0.012
negative regulation of neurogenesis GO:0050768 53 0.012
chitin based cuticle development GO:0040003 49 0.012
eggshell formation GO:0030703 105 0.012
regulation of cell cycle process GO:0010564 181 0.012
skeletal muscle fiber development GO:0048741 3 0.012
organelle assembly GO:0070925 198 0.012
regulation of membrane potential GO:0042391 35 0.012
Human
actin filament based process GO:0030029 220 0.012
intracellular transport GO:0046907 228 0.012
branching involved in open tracheal system development GO:0060446 45 0.012
response to external biotic stimulus GO:0043207 293 0.012
cell maturation GO:0048469 144 0.012
proteolysis GO:0006508 192 0.012
sleep GO:0030431 49 0.012
myotube cell development GO:0014904 3 0.012
positive regulation of nitrogen compound metabolic process GO:0051173 354 0.012
purine ribonucleotide metabolic process GO:0009150 145 0.012
anatomical structure homeostasis GO:0060249 97 0.012
response to starvation GO:0042594 97 0.012
chaeta development GO:0022416 97 0.012
response to endogenous stimulus GO:0009719 119 0.012
transcription from rna polymerase ii promoter GO:0006366 368 0.012
positive regulation of signal transduction GO:0009967 223 0.012
response to nutrient levels GO:0031667 114 0.012
Rat
cellular response to molecule of bacterial origin GO:0071219 3 0.012
morphogenesis of a branching structure GO:0001763 45 0.012
ameboidal type cell migration GO:0001667 151 0.011
anterior posterior pattern specification GO:0009952 136 0.011
nitrogen compound transport GO:0071705 85 0.011
Yeast Rat
amine metabolic process GO:0009308 12 0.011
ribonucleotide catabolic process GO:0009261 109 0.011
response to ketone GO:1901654 34 0.011
Rat
regulation of synaptic transmission GO:0050804 69 0.011
l glutamate import GO:0051938 1 0.011
response to organonitrogen compound GO:0010243 75 0.011
regulation of synapse structure and activity GO:0050803 128 0.011
response to other organism GO:0051707 293 0.011
positive regulation of cell motility GO:2000147 3 0.011
eye photoreceptor cell development GO:0042462 81 0.011
androgen metabolic process GO:0008209 1 0.011
limb morphogenesis GO:0035108 1 0.011
actin filament organization GO:0007015 126 0.011
response to biotic stimulus GO:0009607 294 0.011
regulation of transcription from rna polymerase ii promoter GO:0006357 378 0.011
cell growth GO:0016049 108 0.011
rna processing GO:0006396 147 0.011
autophagy GO:0006914 108 0.011
protein phosphorylation GO:0006468 169 0.011
cellular amine metabolic process GO:0044106 12 0.011
response to ionizing radiation GO:0010212 32 0.011
Rat
regulation of intracellular signal transduction GO:1902531 236 0.011
vitamin biosynthetic process GO:0009110 1 0.011
response to alcohol GO:0097305 95 0.011
Rat
cellular response to organonitrogen compound GO:0071417 36 0.011
Rat
regulation of transport GO:0051049 181 0.011
metal ion transport GO:0030001 74 0.011
urogenital system development GO:0001655 72 0.011
nephron tubule development GO:0072080 3 0.011
associative learning GO:0008306 65 0.011
organic cyclic compound catabolic process GO:1901361 168 0.011
positive regulation of cell migration GO:0030335 2 0.011
regulation of epithelial cell proliferation GO:0050678 4 0.011
regulation of molecular function GO:0065009 217 0.011
anterior posterior axis specification GO:0009948 109 0.011
cellular response to lipopolysaccharide GO:0071222 3 0.011
carbohydrate derivative catabolic process GO:1901136 118 0.011
negative regulation of nucleobase containing compound metabolic process GO:0045934 261 0.011
branching morphogenesis of an epithelial tube GO:0048754 45 0.011
response to hexose GO:0009746 3 0.011
nucleoside metabolic process GO:0009116 127 0.011
muscle structure development GO:0061061 224 0.010
response to decreased oxygen levels GO:0036293 58 0.010
Rat Fly
regulation of mitotic cell cycle phase transition GO:1901990 130 0.010
response to monosaccharide GO:0034284 4 0.010
sensory perception GO:0007600 196 0.010
extrinsic apoptotic signaling pathway GO:0097191 1 0.010
aromatic compound catabolic process GO:0019439 166 0.010
gene silencing GO:0016458 138 0.010
muscle cell development GO:0055001 50 0.010
regulation of epithelial cell differentiation GO:0030856 4 0.010
phosphate ion transport GO:0006817 4 0.010
regulation of multi organism process GO:0043900 131 0.010
enzyme linked receptor protein signaling pathway GO:0007167 179 0.010
autophagic cell death GO:0048102 83 0.010
tissue death GO:0016271 102 0.010
cellular response to biotic stimulus GO:0071216 4 0.010
wound healing GO:0042060 75 0.010
leg disc morphogenesis GO:0007478 80 0.010
regulation of notch signaling pathway GO:0008593 100 0.010
peptidyl threonine phosphorylation GO:0018107 2 0.010

Mdr65 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in fly and predicted with the fly functional network.

Disease DO term ID Size Probability Func Analog Org
disease of anatomical entity DOID:7 0 0.055
Human
nervous system disease DOID:863 0 0.024
musculoskeletal system disease DOID:17 0 0.016
cardiovascular system disease DOID:1287 0 0.016
vascular disease DOID:178 0 0.012
disease of metabolism DOID:0014667 0 0.012
sensory system disease DOID:0050155 0 0.012
bone disease DOID:0080001 0 0.011
connective tissue disease DOID:65 0 0.011
hypertension DOID:10763 0 0.011
artery disease DOID:0050828 0 0.011
central nervous system disease DOID:331 0 0.010