Drosophila melanogaster

11 known processes

crm (Dmel_CG2714)

cramped

(Aliases: l(1)zw9,CG2714,l(1)3C1,swa,Dmel\CG2714,ZW-9,zw9,EG:95B7.2,l(1)3Ca,sa,zw-9,sta[P])

crm biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
negative regulation of nucleobase containing compound metabolic process GO:0045934 261 0.974
chromatin silencing GO:0006342 76 0.900
negative regulation of gene expression epigenetic GO:0045814 77 0.885
negative regulation of nucleic acid templated transcription GO:1903507 240 0.878
negative regulation of cellular macromolecule biosynthetic process GO:2000113 267 0.823
negative regulation of nitrogen compound metabolic process GO:0051172 265 0.822
negative regulation of transcription dna templated GO:0045892 237 0.812
gene silencing GO:0016458 138 0.776
negative regulation of macromolecule biosynthetic process GO:0010558 270 0.775
negative regulation of biosynthetic process GO:0009890 277 0.733
negative regulation of rna metabolic process GO:0051253 251 0.714
negative regulation of gene expression GO:0010629 387 0.650
negative regulation of cellular biosynthetic process GO:0031327 277 0.626
negative regulation of cellular metabolic process GO:0031324 382 0.613
transcription from rna polymerase ii promoter GO:0006366 368 0.604
negative regulation of rna biosynthetic process GO:1902679 240 0.521
chromatin organization GO:0006325 207 0.475
positive regulation of rna metabolic process GO:0051254 271 0.445
covalent chromatin modification GO:0016569 106 0.407
protein modification process GO:0036211 438 0.384
regulation of meiosis GO:0040020 3 0.322
positive regulation of nucleic acid templated transcription GO:1903508 266 0.278
regulation of gene expression epigenetic GO:0040029 128 0.272
rhythmic process GO:0048511 106 0.268
regulation of immune response GO:0050776 118 0.245
regulation of chromatin silencing GO:0031935 36 0.235
cellular response to organic substance GO:0071310 132 0.210
positive regulation of macromolecule biosynthetic process GO:0010557 283 0.208
cellular protein modification process GO:0006464 438 0.201
positive regulation of transcription from rna polymerase ii promoter GO:0045944 204 0.197
positive regulation of nucleobase containing compound metabolic process GO:0045935 332 0.183
positive regulation of gene expression GO:0010628 290 0.177
chromosome organization GO:0051276 360 0.171
regulation of anatomical structure morphogenesis GO:0022603 242 0.160
regulation of organelle organization GO:0033043 196 0.159
positive regulation of macromolecule metabolic process GO:0010604 405 0.153
chromatin modification GO:0016568 147 0.150
cell cycle comprising mitosis without cytokinesis GO:0033301 25 0.147
positive regulation of nitrogen compound metabolic process GO:0051173 354 0.141
regulation of gene silencing GO:0060968 63 0.140
establishment of localization in cell GO:0051649 402 0.133
negative regulation of organelle organization GO:0010639 56 0.126
regulation of growth GO:0040008 233 0.126
spindle organization GO:0007051 253 0.119
cellular response to oxidative stress GO:0034599 28 0.115
positive regulation of cellular biosynthetic process GO:0031328 316 0.109
morphogenesis of an epithelium GO:0002009 276 0.108
open tracheal system development GO:0007424 204 0.100
multi organism behavior GO:0051705 175 0.097
histone modification GO:0016570 106 0.096
hippo signaling GO:0035329 20 0.095
cellular response to dna damage stimulus GO:0006974 223 0.091
positive regulation of transcription dna templated GO:0045893 266 0.090
response to alcohol GO:0097305 95 0.089
microtubule based transport GO:0010970 42 0.086
tissue morphogenesis GO:0048729 297 0.085
response to other organism GO:0051707 293 0.082
chromatin mediated maintenance of transcription GO:0048096 7 0.081
cellular macromolecular complex assembly GO:0034622 153 0.078
intracellular transport GO:0046907 228 0.074
regulation of transcription from rna polymerase ii promoter GO:0006357 378 0.069
regulation of cellular component biogenesis GO:0044087 201 0.067
protein acylation GO:0043543 42 0.067
response to abiotic stimulus GO:0009628 341 0.066
positive regulation of biosynthetic process GO:0009891 316 0.065
protein import into nucleus GO:0006606 51 0.060
response to nitrogen compound GO:1901698 90 0.060
negative regulation of cell differentiation GO:0045596 143 0.057
cellular protein complex assembly GO:0043623 71 0.056
regulation of defense response GO:0031347 102 0.055
circadian rhythm GO:0007623 105 0.055
molting cycle chitin based cuticle GO:0007591 56 0.053
regulation of immune system process GO:0002682 176 0.052
germarium derived egg chamber formation GO:0007293 101 0.052
growth GO:0040007 359 0.052
positive regulation of immune response GO:0050778 63 0.051
cellular response to nitrogen compound GO:1901699 51 0.050
biological adhesion GO:0022610 138 0.050
sarcomere organization GO:0045214 26 0.050
single organism cellular localization GO:1902580 180 0.050
cellular response to oxygen containing compound GO:1901701 79 0.049
positive regulation of jun kinase activity GO:0043507 4 0.049
cellular response to chemical stimulus GO:0070887 199 0.048
imaginal disc derived wing morphogenesis GO:0007476 337 0.046
positive regulation of cellular component organization GO:0051130 156 0.042
protein complex assembly GO:0006461 200 0.042
innate immune response GO:0045087 144 0.042
protein localization to organelle GO:0033365 82 0.042
cell adhesion GO:0007155 136 0.042
response to organic substance GO:0010033 284 0.040
response to external biotic stimulus GO:0043207 293 0.040
oxoacid metabolic process GO:0043436 103 0.040
positive regulation of defense response GO:0031349 59 0.040
regulation of cellular localization GO:0060341 136 0.040
cellular response to endogenous stimulus GO:0071495 80 0.039
cellular protein localization GO:0034613 160 0.039
response to organic cyclic compound GO:0014070 89 0.037
mitotic spindle organization GO:0007052 220 0.037
positive regulation of immune system process GO:0002684 68 0.037
tube morphogenesis GO:0035239 191 0.037
negative regulation of response to stimulus GO:0048585 258 0.035
meiotic nuclear division GO:0007126 151 0.034
regulation of intracellular transport GO:0032386 64 0.034
response to bacterium GO:0009617 198 0.033
regulation of transport GO:0051049 181 0.033
cellular macromolecule localization GO:0070727 220 0.033
positive regulation of protein phosphorylation GO:0001934 34 0.033
reproductive behavior GO:0019098 122 0.033
positive regulation of rna biosynthetic process GO:1902680 266 0.032
phosphorylation GO:0016310 294 0.032
respiratory system development GO:0060541 213 0.031
chromatin remodeling GO:0006338 72 0.031
intracellular protein transport GO:0006886 104 0.030
cellular amino acid metabolic process GO:0006520 61 0.030
regulation of protein metabolic process GO:0051246 256 0.030
establishment of protein localization GO:0045184 163 0.030
organic substance transport GO:0071702 257 0.030
stem cell differentiation GO:0048863 117 0.029
homeostatic process GO:0042592 199 0.029
aging GO:0007568 143 0.029
syncytial blastoderm mitotic cell cycle GO:0035186 21 0.028
regulation of mrna metabolic process GO:1903311 72 0.028
anatomical structure homeostasis GO:0060249 97 0.028
regulation of cellular protein metabolic process GO:0032268 243 0.028
regulation of i kappab kinase nf kappab signaling GO:0043122 2 0.028
regulation of developmental growth GO:0048638 174 0.027
protein alkylation GO:0008213 43 0.027
negative regulation of cellular component organization GO:0051129 108 0.026
response to endogenous stimulus GO:0009719 119 0.026
compound eye photoreceptor cell differentiation GO:0001751 140 0.026
macromolecular complex assembly GO:0065003 256 0.026
regulation of jnk cascade GO:0046328 40 0.026
carbohydrate metabolic process GO:0005975 82 0.025
negative regulation of multicellular organismal process GO:0051241 142 0.025
leg disc morphogenesis GO:0007478 80 0.025
protein localization to nucleus GO:0034504 55 0.025
single organism carbohydrate metabolic process GO:0044723 72 0.024
regulation of cell morphogenesis GO:0022604 163 0.024
secretion by cell GO:0032940 101 0.024
negative regulation of cell cycle process GO:0010948 109 0.024
response to biotic stimulus GO:0009607 294 0.024
defense response GO:0006952 300 0.024
body morphogenesis GO:0010171 2 0.023
response to lipid GO:0033993 38 0.023
cytoskeleton dependent cytokinesis GO:0061640 81 0.023
organonitrogen compound metabolic process GO:1901564 318 0.022
immune response GO:0006955 246 0.022
cell death GO:0008219 279 0.022
regulation of response to stress GO:0080134 200 0.022
cellular response to organic cyclic compound GO:0071407 32 0.022
posttranscriptional regulation of gene expression GO:0010608 145 0.022
histone lysine methylation GO:0034968 32 0.021
regulation of anatomical structure size GO:0090066 163 0.021
regulation of protein modification process GO:0031399 112 0.021
regulation of cell cycle process GO:0010564 181 0.021
dna packaging GO:0006323 91 0.021
gene silencing by rna GO:0031047 57 0.021
regulation of immune effector process GO:0002697 52 0.021
hindbrain development GO:0030902 2 0.020
imaginal disc derived leg morphogenesis GO:0007480 80 0.020
mitotic cell cycle embryonic GO:0045448 38 0.020
regulation of imaginal disc growth GO:0045570 26 0.020
mitotic chromosome condensation GO:0007076 22 0.020
regulation of localization GO:0032879 275 0.020
taxis GO:0042330 304 0.020
heterochromatin organization GO:0070828 25 0.019
immune effector process GO:0002252 98 0.019
regulation of chromatin organization GO:1902275 32 0.019
protein modification by small protein conjugation or removal GO:0070647 106 0.019
organelle assembly GO:0070925 198 0.019
cellular amine metabolic process GO:0044106 12 0.019
carboxylic acid metabolic process GO:0019752 92 0.018
single organism intracellular transport GO:1902582 207 0.018
regulation of protein transport GO:0051223 57 0.018
regulation of mitotic cell cycle GO:0007346 190 0.018
histone methylation GO:0016571 40 0.018
regulation of intracellular protein transport GO:0033157 46 0.017
tube development GO:0035295 244 0.017
negative regulation of gtpase activity GO:0034260 1 0.017
cell division GO:0051301 248 0.017
single organism biosynthetic process GO:0044711 206 0.017
branching involved in open tracheal system development GO:0060446 45 0.017
pigment biosynthetic process GO:0046148 36 0.017
organelle inheritance GO:0048308 2 0.017
regulation of cell cycle GO:0051726 291 0.017
gland development GO:0048732 191 0.017
positive regulation of response to stimulus GO:0048584 323 0.017
response to wounding GO:0009611 94 0.016
regulation of cell division GO:0051302 72 0.016
multicellular organismal reproductive behavior GO:0033057 110 0.016
nuclear transport GO:0051169 72 0.016
protein acetylation GO:0006473 39 0.016
regulation of transcription by chromatin organization GO:0034401 3 0.016
cellular response to lipid GO:0071396 20 0.016
imaginal disc derived appendage development GO:0048737 399 0.016
cell projection assembly GO:0030031 94 0.016
defense response to gram negative bacterium GO:0050829 94 0.016
response to oxygen containing compound GO:1901700 200 0.016
internal peptidyl lysine acetylation GO:0018393 38 0.016
amine metabolic process GO:0009308 12 0.016
dendrite morphogenesis GO:0048813 199 0.016
apoptotic signaling pathway GO:0097190 27 0.016
myofibril assembly GO:0030239 36 0.016
intermediate filament cytoskeleton organization GO:0045104 1 0.016
programmed cell death GO:0012501 257 0.015
response to lipopolysaccharide GO:0032496 4 0.015
negative regulation of transcription from rna polymerase ii promoter GO:0000122 119 0.015
positive regulation of protein metabolic process GO:0051247 128 0.015
skin development GO:0043588 65 0.015
regulation of cell shape GO:0008360 113 0.015
protein transport GO:0015031 155 0.015
glycoprotein metabolic process GO:0009100 41 0.015
response to ketone GO:1901654 34 0.015
axon development GO:0061564 297 0.015
organophosphate metabolic process GO:0019637 195 0.015
regulation of mapk cascade GO:0043408 92 0.015
dna conformation change GO:0071103 105 0.015
signal transduction by phosphorylation GO:0023014 107 0.015
nuclear import GO:0051170 51 0.015
regulation of establishment of protein localization GO:0070201 61 0.014
rna processing GO:0006396 147 0.014
multi organism reproductive behavior GO:0044705 121 0.014
regulation of dna templated transcription elongation GO:0032784 17 0.014
regulation of cellular catabolic process GO:0031329 157 0.014
imaginal disc derived appendage morphogenesis GO:0035114 395 0.014
regulation of innate immune response GO:0045088 71 0.014
organic acid metabolic process GO:0006082 103 0.014
regulation of transcription elongation from rna polymerase ii promoter GO:0034243 15 0.014
negative regulation of sequence specific dna binding transcription factor activity GO:0043433 4 0.014
male courtship behavior GO:0008049 63 0.014
regulation of phosphatase activity GO:0010921 3 0.013
positive regulation of chromatin silencing GO:0031937 16 0.013
response to acid chemical GO:0001101 25 0.013
regulation of molecular function GO:0065009 217 0.013
sister chromatid segregation GO:0000819 92 0.013
protein ubiquitination GO:0016567 70 0.013
lipid metabolic process GO:0006629 121 0.013
regulation of cell differentiation GO:0045595 302 0.013
positive regulation of signaling GO:0023056 243 0.013
dna methylation GO:0006306 4 0.013
cell proliferation GO:0008283 299 0.013
digestive tract development GO:0048565 149 0.012
nitrogen compound transport GO:0071705 85 0.012
protein maturation GO:0051604 71 0.012
meiotic cell cycle GO:0051321 171 0.012
negative regulation of cell communication GO:0010648 223 0.012
dna metabolic process GO:0006259 227 0.012
regulation of protein localization GO:0032880 76 0.012
phagocytosis GO:0006909 215 0.012
regulation of cellular amino acid metabolic process GO:0006521 0 0.012
cellular response to acid chemical GO:0071229 8 0.012
response to hormone GO:0009725 45 0.012
wing disc morphogenesis GO:0007472 344 0.012
response to organophosphorus GO:0046683 2 0.012
cell fate specification GO:0001708 71 0.012
developmental growth GO:0048589 280 0.011
protein targeting to nucleus GO:0044744 51 0.011
axonogenesis GO:0007409 290 0.011
positive regulation of intracellular signal transduction GO:1902533 116 0.011
negative regulation of protein metabolic process GO:0051248 85 0.011
protein import GO:0017038 55 0.011
mating GO:0007618 120 0.011
positive regulation of cell migration GO:0030335 2 0.011
negative regulation of cell cycle GO:0045786 116 0.011
intracellular signal transduction GO:0035556 300 0.011
response to radiation GO:0009314 155 0.011
post embryonic appendage morphogenesis GO:0035120 385 0.011
leg disc development GO:0035218 92 0.011
peptidyl lysine modification GO:0018205 57 0.011
regulation of phosphorus metabolic process GO:0051174 210 0.011
dna templated transcription elongation GO:0006354 18 0.010
protein complex biogenesis GO:0070271 201 0.010
response to ecdysone GO:0035075 34 0.010
histolysis GO:0007559 102 0.010
mapk cascade GO:0000165 107 0.010
metal ion homeostasis GO:0055065 44 0.010
regulation of cell proliferation GO:0042127 163 0.010
death GO:0016265 284 0.010
histone h3 k27 methylation GO:0070734 6 0.010
cellular ketone metabolic process GO:0042180 24 0.010
ribonucleoprotein complex disassembly GO:0032988 1 0.010
carbohydrate derivative metabolic process GO:1901135 217 0.010
regulation of meiotic cell cycle GO:0051445 9 0.010

crm disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in fly and predicted with the fly functional network.

Disease DO term ID Size Probability Func Analog Org
cancer DOID:162 0 0.013
disease of cellular proliferation DOID:14566 0 0.013