Drosophila melanogaster

0 known processes

cals (Dmel_CG11059)

calsyntenin-1

(Aliases: Cals,CT30877,CALS,Cad102F,CG11059,Dmel\CG11059,DCad102F)

cals biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
muscle structure development GO:0061061 224 0.456
negative regulation of cellular biosynthetic process GO:0031327 277 0.437
taxis GO:0042330 304 0.410
chemotaxis GO:0006935 249 0.381
axon guidance GO:0007411 233 0.354
negative regulation of biosynthetic process GO:0009890 277 0.349
vesicle mediated transport GO:0016192 381 0.298
regionalization GO:0003002 416 0.296
protein localization GO:0008104 284 0.281
body morphogenesis GO:0010171 2 0.275
negative regulation of gene expression GO:0010629 387 0.243
endocytosis GO:0006897 310 0.233
carbohydrate derivative biosynthetic process GO:1901137 85 0.232
response to radiation GO:0009314 155 0.232
response to abiotic stimulus GO:0009628 341 0.227
purine containing compound biosynthetic process GO:0072522 30 0.215
appendage development GO:0048736 401 0.212
negative regulation of cellular macromolecule biosynthetic process GO:2000113 267 0.205
regulation of cellular localization GO:0060341 136 0.201
sensory perception GO:0007600 196 0.200
cgmp biosynthetic process GO:0006182 8 0.192
apoptotic process GO:0006915 159 0.187
negative regulation of cellular metabolic process GO:0031324 382 0.181
organelle fission GO:0048285 340 0.179
neurological system process GO:0050877 358 0.175
regulation of protein metabolic process GO:0051246 256 0.154
cyclic nucleotide biosynthetic process GO:0009190 25 0.151
meiotic nuclear division GO:0007126 151 0.150
circadian rhythm GO:0007623 105 0.145
regulation of behavior GO:0050795 75 0.140
regulation of localization GO:0032879 275 0.138
axon development GO:0061564 297 0.138
negative regulation of macromolecule biosynthetic process GO:0010558 270 0.138
cellular macromolecule localization GO:0070727 220 0.132
programmed cell death GO:0012501 257 0.132
cell division GO:0051301 248 0.131
organelle localization GO:0051640 148 0.128
regulation of cell cycle GO:0051726 291 0.126
nuclear division GO:0000280 332 0.123
axonogenesis GO:0007409 290 0.123
regulation of cell shape GO:0008360 113 0.116
single organism behavior GO:0044708 391 0.115
small molecule metabolic process GO:0044281 305 0.114
imaginal disc derived appendage development GO:0048737 399 0.112
positive regulation of cell migration GO:0030335 2 0.108
protein modification process GO:0036211 438 0.105
positive regulation of cell motility GO:2000147 3 0.103
cell migration GO:0016477 238 0.103
synapse organization GO:0050808 196 0.102
dorsal ventral pattern formation GO:0009953 133 0.097
regulation of cell differentiation GO:0045595 302 0.096
regulation of organelle organization GO:0033043 196 0.095
cellular protein modification process GO:0006464 438 0.095
positive regulation of cell development GO:0010720 61 0.092
carbohydrate derivative metabolic process GO:1901135 217 0.092
single organism intracellular transport GO:1902582 207 0.091
response to light stimulus GO:0009416 124 0.089
regulation of cell development GO:0060284 215 0.089
regulation of multi organism process GO:0043900 131 0.088
regulation of reproductive process GO:2000241 54 0.087
macromolecular complex assembly GO:0065003 256 0.086
cellular response to chemical stimulus GO:0070887 199 0.086
phagocytosis GO:0006909 215 0.084
organonitrogen compound metabolic process GO:1901564 318 0.081
central nervous system development GO:0007417 201 0.081
cgmp metabolic process GO:0046068 11 0.080
histone modification GO:0016570 106 0.080
epithelial cell differentiation GO:0030855 322 0.079
cellular response to dna damage stimulus GO:0006974 223 0.079
regulation of programmed cell death GO:0043067 152 0.078
glycoprotein biosynthetic process GO:0009101 41 0.077
cell motility GO:0048870 251 0.075
detection of stimulus GO:0051606 156 0.075
post embryonic appendage morphogenesis GO:0035120 385 0.074
muscle cell differentiation GO:0042692 103 0.072
positive regulation of protein metabolic process GO:0051247 128 0.072
immune system process GO:0002376 347 0.072
negative regulation of response to stimulus GO:0048585 258 0.071
establishment of protein localization GO:0045184 163 0.070
locomotory behavior GO:0007626 176 0.067
negative regulation of nucleobase containing compound metabolic process GO:0045934 261 0.067
multi organism behavior GO:0051705 175 0.067
phosphorylation GO:0016310 294 0.066
glycoprotein metabolic process GO:0009100 41 0.064
notch signaling pathway GO:0007219 120 0.064
anterior posterior pattern specification GO:0009952 136 0.064
tissue morphogenesis GO:0048729 297 0.062
regulation of neurogenesis GO:0050767 158 0.062
neuron projection guidance GO:0097485 241 0.061
regulation of gene expression epigenetic GO:0040029 128 0.061
ras protein signal transduction GO:0007265 88 0.060
imaginal disc derived appendage morphogenesis GO:0035114 395 0.058
cellular protein localization GO:0034613 160 0.055
negative regulation of rna biosynthetic process GO:1902679 240 0.054
forebrain development GO:0030900 2 0.054
protein phosphorylation GO:0006468 169 0.053
oocyte development GO:0048599 124 0.053
positive regulation of biosynthetic process GO:0009891 316 0.052
nucleotide metabolic process GO:0009117 161 0.052
wing disc morphogenesis GO:0007472 344 0.052
establishment of localization in cell GO:0051649 402 0.051
purine containing compound metabolic process GO:0072521 155 0.050
dna integrity checkpoint GO:0031570 81 0.050
regulation of neuron differentiation GO:0045664 103 0.049
regulation of multicellular organismal development GO:2000026 414 0.049
biological adhesion GO:0022610 138 0.048
regulation of protein transport GO:0051223 57 0.048
meiotic cell cycle GO:0051321 171 0.047
negative regulation of programmed cell death GO:0043069 72 0.046
ameboidal type cell migration GO:0001667 151 0.046
actin cytoskeleton organization GO:0030036 206 0.046
intracellular transport GO:0046907 228 0.046
organic substance catabolic process GO:1901575 308 0.045
developmental growth GO:0048589 280 0.045
embryonic pattern specification GO:0009880 174 0.044
embryo development ending in birth or egg hatching GO:0009792 152 0.044
positive regulation of cellular biosynthetic process GO:0031328 316 0.044
intracellular protein transport GO:0006886 104 0.043
regulation of cell cycle process GO:0010564 181 0.043
cell adhesion GO:0007155 136 0.043
positive regulation of molecular function GO:0044093 136 0.042
larval development GO:0002164 104 0.042
carboxylic acid metabolic process GO:0019752 92 0.042
single organism biosynthetic process GO:0044711 206 0.042
chemosensory behavior GO:0007635 106 0.042
positive regulation of cell communication GO:0010647 250 0.042
positive regulation of cell death GO:0010942 69 0.041
catabolic process GO:0009056 409 0.041
regulation of establishment of protein localization GO:0070201 61 0.041
cell maturation GO:0048469 144 0.040
positive regulation of nitrogen compound metabolic process GO:0051173 354 0.040
purine ribonucleotide metabolic process GO:0009150 145 0.039
protein transport GO:0015031 155 0.039
growth GO:0040007 359 0.038
chromosome organization GO:0051276 360 0.038
regulation of response to external stimulus GO:0032101 115 0.038
death GO:0016265 284 0.038
purine nucleotide metabolic process GO:0006163 146 0.037
localization of cell GO:0051674 257 0.037
nucleoside phosphate metabolic process GO:0006753 162 0.037
positive regulation of macromolecule metabolic process GO:0010604 405 0.037
positive regulation of response to stimulus GO:0048584 323 0.036
negative regulation of nervous system development GO:0051961 92 0.036
camera type eye development GO:0043010 4 0.036
chromosome segregation GO:0007059 157 0.036
single organism catabolic process GO:0044712 228 0.036
cardiovascular system development GO:0072358 82 0.036
organonitrogen compound biosynthetic process GO:1901566 117 0.035
oocyte differentiation GO:0009994 145 0.035
regulation of nucleocytoplasmic transport GO:0046822 35 0.035
negative regulation of rna metabolic process GO:0051253 251 0.034
positive regulation of purine nucleotide biosynthetic process GO:1900373 10 0.034
regulation of cytoplasmic transport GO:1903649 47 0.033
telencephalon development GO:0021537 2 0.033
carbohydrate metabolic process GO:0005975 82 0.033
tube morphogenesis GO:0035239 191 0.032
single organism carbohydrate metabolic process GO:0044723 72 0.032
regulation of sequence specific dna binding transcription factor activity GO:0051090 12 0.032
organic substance transport GO:0071702 257 0.032
regulation of protein localization GO:0032880 76 0.031
secretion by cell GO:0032940 101 0.031
cell death GO:0008219 279 0.031
regulation of protein modification process GO:0031399 112 0.031
regulation of oviposition GO:0046662 14 0.031
anterior posterior axis specification embryo GO:0008595 103 0.031
positive regulation of transport GO:0051050 92 0.030
response to organonitrogen compound GO:0010243 75 0.030
multi multicellular organism process GO:0044706 123 0.030
regulation of intracellular signal transduction GO:1902531 236 0.030
positive regulation of signaling GO:0023056 243 0.030
regulation of phosphorus metabolic process GO:0051174 210 0.029
positive regulation of catalytic activity GO:0043085 118 0.029
cellular catabolic process GO:0044248 372 0.029
single organism cellular localization GO:1902580 180 0.029
axis specification GO:0009798 167 0.029
imaginal disc derived wing morphogenesis GO:0007476 337 0.029
developmental maturation GO:0021700 172 0.029
regulation of cell death GO:0010941 173 0.028
response to organic substance GO:0010033 284 0.028
regulation of notch signaling pathway GO:0008593 100 0.028
organophosphate metabolic process GO:0019637 195 0.028
negative regulation of nitrogen compound metabolic process GO:0051172 265 0.027
lateral inhibition GO:0046331 206 0.027
positive regulation of phosphorus metabolic process GO:0010562 139 0.027
ribonucleotide metabolic process GO:0009259 145 0.027
neuron recognition GO:0008038 101 0.026
neuromuscular junction development GO:0007528 149 0.026
regulation of cellular component biogenesis GO:0044087 201 0.026
regulation of molecular function GO:0065009 217 0.026
protein localization to nucleus GO:0034504 55 0.026
negative regulation of nucleic acid templated transcription GO:1903507 240 0.026
peptidyl amino acid modification GO:0018193 105 0.026
ribose phosphate metabolic process GO:0019693 145 0.025
positive regulation of neuron differentiation GO:0045666 26 0.025
response to temperature stimulus GO:0009266 106 0.025
oxoacid metabolic process GO:0043436 103 0.025
morphogenesis of an epithelium GO:0002009 276 0.025
immune system development GO:0002520 57 0.025
cell cell signaling involved in cell fate commitment GO:0045168 210 0.025
spindle organization GO:0007051 253 0.024
leg disc morphogenesis GO:0007478 80 0.024
regulation of transport GO:0051049 181 0.024
glycosyl compound catabolic process GO:1901658 112 0.024
circulatory system development GO:0072359 82 0.024
tripartite regional subdivision GO:0007351 103 0.024
intracellular signal transduction GO:0035556 300 0.024
protein catabolic process GO:0030163 101 0.024
visual perception GO:0007601 9 0.024
negative regulation of transcription dna templated GO:0045892 237 0.024
sensory perception of chemical stimulus GO:0007606 116 0.024
regulation of locomotion GO:0040012 42 0.023
chromatin modification GO:0016568 147 0.023
regulation of epithelial cell differentiation GO:0030856 4 0.023
regulation of synapse structure and activity GO:0050803 128 0.023
regulation of response to stress GO:0080134 200 0.023
regulation of apoptotic process GO:0042981 130 0.023
organophosphate biosynthetic process GO:0090407 46 0.023
regulation of intracellular transport GO:0032386 64 0.023
regulation of dna metabolic process GO:0051052 34 0.023
limb morphogenesis GO:0035108 1 0.022
centrosome organization GO:0051297 163 0.022
cellular response to organic substance GO:0071310 132 0.022
negative regulation of cell cycle GO:0045786 116 0.022
negative regulation of cell differentiation GO:0045596 143 0.022
enzyme linked receptor protein signaling pathway GO:0007167 179 0.022
segmentation GO:0035282 207 0.022
organic acid metabolic process GO:0006082 103 0.022
organic cyclic compound catabolic process GO:1901361 168 0.022
oocyte anterior posterior axis specification GO:0007314 72 0.022
maintenance of location GO:0051235 73 0.022
nuclear transport GO:0051169 72 0.021
positive regulation of apoptotic process GO:0043065 47 0.021
cellular carbohydrate metabolic process GO:0044262 22 0.021
response to external biotic stimulus GO:0043207 293 0.021
regulation of cellular protein metabolic process GO:0032268 243 0.021
response to nutrient levels GO:0031667 114 0.021
regulation of oocyte development GO:0060281 27 0.021
mitochondrion organization GO:0007005 65 0.021
embryonic development via the syncytial blastoderm GO:0001700 148 0.021
cellular amine metabolic process GO:0044106 12 0.021
oocyte construction GO:0007308 112 0.021
negative regulation of growth GO:0045926 84 0.021
multicellular organismal reproductive behavior GO:0033057 110 0.021
regulation of gene silencing GO:0060968 63 0.021
regulation of cellular ketone metabolic process GO:0010565 3 0.021
positive regulation of signal transduction GO:0009967 223 0.020
negative regulation of developmental process GO:0051093 201 0.020
regulation of cell division GO:0051302 72 0.020
response to nitrogen compound GO:1901698 90 0.020
positive regulation of multicellular organismal process GO:0051240 143 0.020
tissue migration GO:0090130 155 0.020
oxidation reduction process GO:0055114 123 0.020
positive regulation of nucleic acid templated transcription GO:1903508 266 0.020
nucleobase containing small molecule metabolic process GO:0055086 174 0.019
negative regulation of multicellular organismal process GO:0051241 142 0.019
regulation of cell morphogenesis GO:0022604 163 0.019
striated muscle cell differentiation GO:0051146 90 0.019
regulation of embryonic development GO:0045995 68 0.019
cellular response to high light intensity GO:0071486 1 0.019
regulation of catalytic activity GO:0050790 185 0.019
anatomical structure homeostasis GO:0060249 97 0.019
regulation of growth GO:0040008 233 0.019
imaginal disc derived leg morphogenesis GO:0007480 80 0.019
establishment or maintenance of cell polarity GO:0007163 167 0.019
germarium derived egg chamber formation GO:0007293 101 0.019
regulation of nuclear division GO:0051783 58 0.018
organelle assembly GO:0070925 198 0.018
appendage morphogenesis GO:0035107 397 0.018
multicellular organismal aging GO:0010259 140 0.018
positive regulation of programmed cell death GO:0043068 62 0.018
response to oxidative stress GO:0006979 86 0.018
cellular response to abiotic stimulus GO:0071214 58 0.018
protein targeting GO:0006605 64 0.018
circadian behavior GO:0048512 76 0.018
ribonucleotide biosynthetic process GO:0009260 28 0.018
hematopoietic or lymphoid organ development GO:0048534 57 0.018
chromatin silencing GO:0006342 76 0.018
oocyte axis specification GO:0007309 108 0.018
amine metabolic process GO:0009308 12 0.018
secretion GO:0046903 109 0.017
connective tissue development GO:0061448 3 0.017
regulation of intracellular protein transport GO:0033157 46 0.017
positive regulation of nucleobase containing compound metabolic process GO:0045935 332 0.017
cell fate determination GO:0001709 91 0.017
establishment of organelle localization GO:0051656 122 0.017
regulation of cell projection organization GO:0031344 92 0.017
regulation of cellular component movement GO:0051270 42 0.017
meiotic chromosome segregation GO:0045132 59 0.017
regulation of neuron projection development GO:0010975 69 0.017
cyclic purine nucleotide metabolic process GO:0052652 25 0.017
cellular macromolecular complex assembly GO:0034622 153 0.017
heart development GO:0007507 82 0.016
microtubule organizing center organization GO:0031023 168 0.016
regulation of secretion GO:0051046 44 0.016
olfactory behavior GO:0042048 97 0.016
cell cycle checkpoint GO:0000075 95 0.016
positive regulation of cell differentiation GO:0045597 64 0.016
mitotic nuclear division GO:0007067 213 0.016
positive regulation of neurogenesis GO:0050769 41 0.016
positive regulation of cell projection organization GO:0031346 29 0.016
nucleoside phosphate biosynthetic process GO:1901293 34 0.016
positive regulation of cellular component organization GO:0051130 156 0.016
protein complex biogenesis GO:0070271 201 0.016
regulation of cellular catabolic process GO:0031329 157 0.016
regulation of chromatin silencing GO:0031935 36 0.016
regulation of cell migration GO:0030334 22 0.016
regulation of cell motility GO:2000145 23 0.016
morphogenesis of embryonic epithelium GO:0016331 94 0.015
regulation of meiosis GO:0040020 3 0.015
cellular component assembly involved in morphogenesis GO:0010927 151 0.015
regulation of immune system process GO:0002682 176 0.015
transmembrane receptor protein tyrosine kinase signaling pathway GO:0007169 116 0.015
microtubule polymerization or depolymerization GO:0031109 39 0.015
lipid storage GO:0019915 38 0.015
regulation of catabolic process GO:0009894 170 0.015
regulation of phosphate metabolic process GO:0019220 210 0.015
negative regulation of cell development GO:0010721 62 0.015
positive regulation of intracellular protein transport GO:0090316 30 0.014
cellular ketone metabolic process GO:0042180 24 0.014
dna replication GO:0006260 48 0.014
cell cycle phase transition GO:0044770 140 0.014
negative regulation of cell cycle phase transition GO:1901988 103 0.014
smoothened signaling pathway GO:0007224 49 0.014
gene silencing GO:0016458 138 0.014
positive regulation of notch signaling pathway GO:0045747 34 0.014
cellular protein complex assembly GO:0043623 71 0.014
positive regulation of protein modification process GO:0031401 58 0.014
dna metabolic process GO:0006259 227 0.014
small gtpase mediated signal transduction GO:0007264 88 0.014
long chain fatty acid metabolic process GO:0001676 3 0.014
homeostatic process GO:0042592 199 0.014
asymmetric protein localization GO:0008105 33 0.014
aging GO:0007568 143 0.014
cellular response to endogenous stimulus GO:0071495 80 0.014
multi organism reproductive behavior GO:0044705 121 0.014
phototaxis GO:0042331 21 0.013
cellular macromolecule catabolic process GO:0044265 136 0.013
response to biotic stimulus GO:0009607 294 0.013
spermatogenesis GO:0007283 200 0.013
regulation of mitotic cell cycle GO:0007346 190 0.013
embryonic morphogenesis GO:0048598 206 0.013
nucleocytoplasmic transport GO:0006913 72 0.013
tube development GO:0035295 244 0.013
cytoplasmic transport GO:0016482 130 0.013
epithelial cell migration GO:0010631 148 0.013
ion transport GO:0006811 145 0.013
regulation of cell cycle phase transition GO:1901987 130 0.013
energy derivation by oxidation of organic compounds GO:0015980 32 0.013
lipid metabolic process GO:0006629 121 0.013
regulation of nucleotide metabolic process GO:0006140 62 0.013
rna localization GO:0006403 115 0.013
muscle organ development GO:0007517 127 0.013
stem cell proliferation GO:0072089 88 0.013
macromolecule glycosylation GO:0043413 32 0.013
positive regulation of phosphorylation GO:0042327 87 0.013
dna alkylation GO:0006305 4 0.013
positive regulation of cellular protein metabolic process GO:0032270 118 0.012
regulation of cgmp metabolic process GO:0030823 1 0.012
mitotic cell cycle phase transition GO:0044772 138 0.012
covalent chromatin modification GO:0016569 106 0.012
regulation of synaptic transmission GO:0050804 69 0.012
regulation of cellular amino acid metabolic process GO:0006521 0 0.012
regulation of hemocyte proliferation GO:0035206 37 0.012
negative regulation of apoptotic process GO:0043066 63 0.012
transcription from rna polymerase ii promoter GO:0006366 368 0.012
carbohydrate derivative catabolic process GO:1901136 118 0.012
neuronal action potential GO:0019228 10 0.012
generation of precursor metabolites and energy GO:0006091 42 0.012
cellular amino acid metabolic process GO:0006520 61 0.012
negative regulation of response to external stimulus GO:0032102 22 0.012
ribonucleoside catabolic process GO:0042454 112 0.012
cell recognition GO:0008037 102 0.012
reproductive structure development GO:0048608 74 0.012
positive regulation of phosphate metabolic process GO:0045937 139 0.012
meiotic cell cycle process GO:1903046 132 0.012
response to bacterium GO:0009617 198 0.012
regulation of synapse organization GO:0050807 110 0.012
cell proliferation GO:0008283 299 0.012
negative regulation of mitotic cell cycle GO:0045930 109 0.012
ovarian follicle cell development GO:0030707 248 0.012
regulation of protein complex assembly GO:0043254 42 0.012
regulation of phosphorylation GO:0042325 147 0.011
chromatin organization GO:0006325 207 0.011
embryonic axis specification GO:0000578 107 0.011
response to wounding GO:0009611 94 0.011
negative regulation of gene expression epigenetic GO:0045814 77 0.011
gonad development GO:0008406 50 0.011
determination of adult lifespan GO:0008340 137 0.011
hindbrain development GO:0030902 2 0.011
regulation of developmental growth GO:0048638 174 0.011
mitotic cell cycle checkpoint GO:0007093 88 0.011
regulation of purine nucleotide metabolic process GO:1900542 62 0.011
positive regulation of locomotion GO:0040017 8 0.011
positive regulation of lyase activity GO:0051349 10 0.011
negative regulation of cell communication GO:0010648 223 0.011
memory GO:0007613 94 0.011
nucleotide catabolic process GO:0009166 109 0.011
hemopoiesis GO:0030097 46 0.011
brain development GO:0007420 120 0.011
nucleotide biosynthetic process GO:0009165 34 0.011
cellular lipid metabolic process GO:0044255 83 0.011
spinal cord dorsal ventral patterning GO:0021513 1 0.011
anterior posterior axis specification GO:0009948 109 0.011
detection of abiotic stimulus GO:0009582 66 0.011
kidney development GO:0001822 3 0.010
nucleoside phosphate catabolic process GO:1901292 110 0.010
regulation of vesicle mediated transport GO:0060627 59 0.010
eye development GO:0001654 323 0.010
nitrogen compound transport GO:0071705 85 0.010
synaptic transmission GO:0007268 288 0.010
steroid catabolic process GO:0006706 1 0.010
macromolecule methylation GO:0043414 45 0.010
regulation of anatomical structure morphogenesis GO:0022603 242 0.010
positive regulation of protein kinase activity GO:0045860 25 0.010
cellular response to decreased oxygen levels GO:0036294 30 0.010

cals disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in fly and predicted with the fly functional network.

Disease DO term ID Size Probability Func Analog Org
disease of anatomical entity DOID:7 0 0.062
disease of metabolism DOID:0014667 0 0.038
cancer DOID:162 0 0.023
disease of cellular proliferation DOID:14566 0 0.023
bone disease DOID:0080001 0 0.023
musculoskeletal system disease DOID:17 0 0.023
connective tissue disease DOID:65 0 0.023
myopathy DOID:423 0 0.017
muscular disease DOID:0080000 0 0.017
muscle tissue disease DOID:66 0 0.017
bone development disease DOID:0080006 0 0.013
organ system cancer DOID:0050686 0 0.011