Drosophila melanogaster

0 known processes

Graf (Dmel_CG8948)

CG8948 gene product from transcript CG8948-RB

(Aliases: D-Graf,Dmel\CG8948,CG8948)

Graf biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
imaginal disc derived appendage development GO:0048737 399 0.650
appendage development GO:0048736 401 0.365
transmembrane transport GO:0055085 139 0.337
post embryonic appendage morphogenesis GO:0035120 385 0.319
regulation of multicellular organismal development GO:2000026 414 0.282
appendage morphogenesis GO:0035107 397 0.272
imaginal disc derived appendage morphogenesis GO:0035114 395 0.173
inorganic ion transmembrane transport GO:0098660 73 0.138
cell death GO:0008219 279 0.135
Mouse
positive regulation of nitrogen compound metabolic process GO:0051173 354 0.129
Mouse
imaginal disc derived leg morphogenesis GO:0007480 80 0.121
aromatic compound catabolic process GO:0019439 166 0.120
Mouse
intracellular signal transduction GO:0035556 300 0.119
positive regulation of rho gtpase activity GO:0032321 19 0.119
Mouse
wing disc morphogenesis GO:0007472 344 0.109
cellular catabolic process GO:0044248 372 0.103
Mouse
cell migration GO:0016477 238 0.102
small molecule metabolic process GO:0044281 305 0.102
Mouse
nucleoside triphosphate catabolic process GO:0009143 108 0.099
Mouse
response to biotic stimulus GO:0009607 294 0.095
catabolic process GO:0009056 409 0.094
Mouse
cell motility GO:0048870 251 0.092
regulation of localization GO:0032879 275 0.090
endocytosis GO:0006897 310 0.086
epithelial cell development GO:0002064 274 0.084
organic substance catabolic process GO:1901575 308 0.083
Mouse
response to external biotic stimulus GO:0043207 293 0.081
ribonucleoside catabolic process GO:0042454 112 0.079
Mouse
cation transport GO:0006812 110 0.079
cell recognition GO:0008037 102 0.079
regulation of cell differentiation GO:0045595 302 0.078
positive regulation of biosynthetic process GO:0009891 316 0.077
regulation of immune system process GO:0002682 176 0.076
localization of cell GO:0051674 257 0.076
positive regulation of gtp catabolic process GO:0033126 43 0.076
Mouse
taxis GO:0042330 304 0.074
ion transmembrane transport GO:0034220 122 0.073
positive regulation of gtpase activity GO:0043547 43 0.073
Mouse
body morphogenesis GO:0010171 2 0.071
response to organic substance GO:0010033 284 0.070
glycosyl compound catabolic process GO:1901658 112 0.070
Mouse
positive regulation of nucleoside metabolic process GO:0045979 47 0.068
Mouse
chloride transport GO:0006821 10 0.068
glycosyl compound metabolic process GO:1901657 127 0.068
Mouse
positive regulation of ras gtpase activity GO:0032320 36 0.067
Mouse
positive regulation of cellular component biogenesis GO:0044089 80 0.066
purine containing compound metabolic process GO:0072521 155 0.064
Mouse
imaginal disc derived wing morphogenesis GO:0007476 337 0.064
epithelial cell differentiation GO:0030855 322 0.060
carboxylic acid metabolic process GO:0019752 92 0.059
regulation of phosphorus metabolic process GO:0051174 210 0.058
Mouse
segmentation GO:0035282 207 0.058
establishment of localization in cell GO:0051649 402 0.055
vesicle mediated transport GO:0016192 381 0.054
regulation of neuron differentiation GO:0045664 103 0.054
heterocycle catabolic process GO:0046700 166 0.054
Mouse
single organism catabolic process GO:0044712 228 0.054
Mouse
purine nucleoside metabolic process GO:0042278 127 0.053
Mouse
negative regulation of cell communication GO:0010648 223 0.053
regulation of ras protein signal transduction GO:0046578 93 0.053
Mouse
neuron recognition GO:0008038 101 0.052
regulation of anatomical structure morphogenesis GO:0022603 242 0.052
regulation of molecular function GO:0065009 217 0.050
Mouse
axonogenesis GO:0007409 290 0.050
leg disc morphogenesis GO:0007478 80 0.049
regulation of anatomical structure size GO:0090066 163 0.048
embryonic morphogenesis GO:0048598 206 0.048
purine nucleoside triphosphate catabolic process GO:0009146 108 0.048
Mouse
small gtpase mediated signal transduction GO:0007264 88 0.047
dendrite development GO:0016358 204 0.046
regulation of cellular component biogenesis GO:0044087 201 0.045
axon development GO:0061564 297 0.045
nucleobase containing small molecule metabolic process GO:0055086 174 0.045
Mouse
organonitrogen compound catabolic process GO:1901565 128 0.045
Mouse
purine nucleoside triphosphate metabolic process GO:0009144 119 0.045
Mouse
response to other organism GO:0051707 293 0.044
rubidium ion transport GO:0035826 1 0.044
purine ribonucleoside metabolic process GO:0046128 127 0.044
Mouse
negative regulation of signaling GO:0023057 219 0.044
centrosome organization GO:0051297 163 0.044
organophosphate catabolic process GO:0046434 112 0.043
Mouse
leg disc development GO:0035218 92 0.043
purine ribonucleotide metabolic process GO:0009150 145 0.043
Mouse
tube development GO:0035295 244 0.043
positive regulation of macromolecule biosynthetic process GO:0010557 283 0.042
nucleoside triphosphate metabolic process GO:0009141 120 0.042
Mouse
negative regulation of epidermal growth factor receptor signaling pathway GO:0042059 29 0.041
purine containing compound catabolic process GO:0072523 112 0.041
Mouse
nucleoside phosphate catabolic process GO:1901292 110 0.041
Mouse
regulation of gtpase activity GO:0043087 44 0.041
Mouse
ras protein signal transduction GO:0007265 88 0.041
microtubule organizing center organization GO:0031023 168 0.041
purine nucleotide catabolic process GO:0006195 109 0.040
Mouse
positive regulation of macromolecule metabolic process GO:0010604 405 0.039
regulation of nucleoside metabolic process GO:0009118 50 0.039
Mouse
response to oxygen containing compound GO:1901700 200 0.039
chromosome organization GO:0051276 360 0.038
transcription from rna polymerase ii promoter GO:0006366 368 0.038
regulation of nucleotide catabolic process GO:0030811 48 0.038
Mouse
programmed cell death GO:0012501 257 0.037
Mouse
enzyme linked receptor protein signaling pathway GO:0007167 179 0.037
positive regulation of rna biosynthetic process GO:1902680 266 0.037
neuron projection guidance GO:0097485 241 0.037
developmental cell growth GO:0048588 52 0.037
epithelial cell migration GO:0010631 148 0.036
regulation of cellular amine metabolic process GO:0033238 3 0.036
ion transport GO:0006811 145 0.036
nucleoside catabolic process GO:0009164 112 0.036
Mouse
organelle localization GO:0051640 148 0.036
regulation of apoptotic process GO:0042981 130 0.036
Mouse
regulation of gtp catabolic process GO:0033124 44 0.036
Mouse
regulation of cytoskeleton organization GO:0051493 89 0.035
regulation of transcription from rna polymerase ii promoter GO:0006357 378 0.035
regulation of epidermal growth factor receptor signaling pathway GO:0042058 42 0.034
positive regulation of cellular biosynthetic process GO:0031328 316 0.033
carbohydrate derivative catabolic process GO:1901136 118 0.033
Mouse
neuron projection extension GO:1990138 32 0.033
positive regulation of cell communication GO:0010647 250 0.033
regulation of organ morphogenesis GO:2000027 78 0.033
synaptic target recognition GO:0008039 45 0.033
cellular response to radiation GO:0071478 52 0.032
nucleotide metabolic process GO:0009117 161 0.032
Mouse
positive regulation of cell motility GO:2000147 3 0.032
regulation of cell development GO:0060284 215 0.032
purine ribonucleotide catabolic process GO:0009154 109 0.031
Mouse
cellular response to biotic stimulus GO:0071216 4 0.031
regulation of catalytic activity GO:0050790 185 0.031
Mouse
negative regulation of signal transduction GO:0009968 206 0.030
epidermal growth factor receptor signaling pathway GO:0007173 58 0.030
phosphorylation GO:0016310 294 0.030
positive regulation of cellular catabolic process GO:0031331 95 0.030
Mouse
organonitrogen compound metabolic process GO:1901564 318 0.030
Mouse
regionalization GO:0003002 416 0.030
macromolecule catabolic process GO:0009057 161 0.030
nucleoside metabolic process GO:0009116 127 0.030
Mouse
negative regulation of response to stimulus GO:0048585 258 0.030
purine ribonucleoside triphosphate catabolic process GO:0009207 108 0.029
Mouse
developmental growth involved in morphogenesis GO:0060560 65 0.029
regulation of cell proliferation GO:0042127 163 0.029
regulation of cellular component movement GO:0051270 42 0.029
organic substance transport GO:0071702 257 0.029
purine nucleotide metabolic process GO:0006163 146 0.029
Mouse
regulation of cellular catabolic process GO:0031329 157 0.029
Mouse
eye photoreceptor cell differentiation GO:0001754 145 0.029
connective tissue development GO:0061448 3 0.029
regulation of ras gtpase activity GO:0032318 38 0.028
Mouse
negative regulation of nucleic acid templated transcription GO:1903507 240 0.028
negative regulation of cellular metabolic process GO:0031324 382 0.028
regulation of erbb signaling pathway GO:1901184 42 0.028
digestive system development GO:0055123 149 0.028
guanosine containing compound metabolic process GO:1901068 74 0.027
Mouse
ribonucleoside triphosphate catabolic process GO:0009203 108 0.027
Mouse
regulation of organelle organization GO:0033043 196 0.027
positive regulation of rna metabolic process GO:0051254 271 0.027
regulation of cellular ketone metabolic process GO:0010565 3 0.027
erbb signaling pathway GO:0038127 58 0.027
transmembrane receptor protein tyrosine kinase signaling pathway GO:0007169 116 0.027
regulation of nucleotide metabolic process GO:0006140 62 0.027
Mouse
mesenchymal cell differentiation GO:0048762 1 0.027
purine ribonucleoside triphosphate metabolic process GO:0009205 119 0.027
Mouse
purine ribonucleoside catabolic process GO:0046130 112 0.026
Mouse
regulation of nervous system development GO:0051960 248 0.026
compound eye photoreceptor cell differentiation GO:0001751 140 0.026
carbohydrate derivative metabolic process GO:1901135 217 0.026
Mouse
cellular nitrogen compound catabolic process GO:0044270 165 0.026
Mouse
negative regulation of gene expression GO:0010629 387 0.026
regulation of cellular amino acid metabolic process GO:0006521 0 0.025
monovalent inorganic cation transport GO:0015672 40 0.025
protein modification process GO:0036211 438 0.025
cellular response to chemical stimulus GO:0070887 199 0.025
regulation of intracellular signal transduction GO:1902531 236 0.025
Mouse
positive regulation of synapse assembly GO:0051965 29 0.025
columnar cuboidal epithelial cell development GO:0002066 249 0.025
apoptotic process GO:0006915 159 0.025
Mouse
actin filament based process GO:0030029 220 0.024
macromolecular complex assembly GO:0065003 256 0.024
cation homeostasis GO:0055080 51 0.024
spindle organization GO:0007051 253 0.024
cell proliferation GO:0008283 299 0.024
response to alcohol GO:0097305 95 0.024
nucleobase containing compound catabolic process GO:0034655 165 0.024
Mouse
epidermal cell differentiation GO:0009913 51 0.024
regulation of axonogenesis GO:0050770 32 0.024
positive regulation of nucleobase containing compound metabolic process GO:0045935 332 0.023
Mouse
positive regulation of cellular component organization GO:0051130 156 0.023
response to endogenous stimulus GO:0009719 119 0.023
negative regulation of erbb signaling pathway GO:1901185 29 0.023
positive regulation of nucleic acid templated transcription GO:1903508 266 0.023
nucleocytoplasmic transport GO:0006913 72 0.023
positive regulation of purine nucleotide metabolic process GO:1900544 55 0.023
Mouse
chromatin organization GO:0006325 207 0.022
ovarian follicle cell development GO:0030707 248 0.022
regulation of cell morphogenesis GO:0022604 163 0.022
organic cyclic compound catabolic process GO:1901361 168 0.022
Mouse
rho protein signal transduction GO:0007266 14 0.022
positive regulation of catabolic process GO:0009896 105 0.022
Mouse
regulation of phosphate metabolic process GO:0019220 210 0.021
Mouse
ribonucleotide metabolic process GO:0009259 145 0.021
Mouse
positive regulation of catalytic activity GO:0043085 118 0.021
Mouse
cell adhesion GO:0007155 136 0.021
cellular protein modification process GO:0006464 438 0.021
cellular ketone metabolic process GO:0042180 24 0.021
lipid metabolic process GO:0006629 121 0.021
blastoderm segmentation GO:0007350 159 0.021
nucleotide catabolic process GO:0009166 109 0.021
Mouse
cellular response to organic substance GO:0071310 132 0.021
metal ion transport GO:0030001 74 0.021
phagocytosis GO:0006909 215 0.021
ribose phosphate metabolic process GO:0019693 145 0.020
Mouse
biological adhesion GO:0022610 138 0.020
ribonucleotide catabolic process GO:0009261 109 0.020
Mouse
anion transmembrane transport GO:0098656 26 0.020
positive regulation of transcription from rna polymerase ii promoter GO:0045944 204 0.020
establishment or maintenance of cell polarity GO:0007163 167 0.020
positive regulation of gene expression GO:0010628 290 0.020
actomyosin structure organization GO:0031032 56 0.020
ovarian follicle cell migration GO:0007297 121 0.020
bmp signaling pathway GO:0030509 27 0.020
positive regulation of signal transduction GO:0009967 223 0.020
regulation of immune response GO:0050776 118 0.020
actin filament organization GO:0007015 126 0.020
digestive tract development GO:0048565 149 0.019
protein complex assembly GO:0006461 200 0.019
cellular polysaccharide biosynthetic process GO:0033692 7 0.019
chromatin remodeling GO:0006338 72 0.019
regulation of cytoplasmic transport GO:1903649 47 0.019
positive regulation of purine nucleotide catabolic process GO:0033123 46 0.019
Mouse
oxoacid metabolic process GO:0043436 103 0.019
regulation of small gtpase mediated signal transduction GO:0051056 93 0.019
Mouse
notch signaling pathway GO:0007219 120 0.019
embryonic development via the syncytial blastoderm GO:0001700 148 0.019
regulation of cellular localization GO:0060341 136 0.019
response to lipopolysaccharide GO:0032496 4 0.019
immune response regulating signaling pathway GO:0002764 2 0.019
positive regulation of phosphate metabolic process GO:0045937 139 0.018
Mouse
positive regulation of transcription dna templated GO:0045893 266 0.018
compound eye development GO:0048749 307 0.018
purine nucleoside catabolic process GO:0006152 112 0.018
Mouse
axon guidance GO:0007411 233 0.018
regulation of synapse organization GO:0050807 110 0.018
embryo development ending in birth or egg hatching GO:0009792 152 0.018
hematopoietic or lymphoid organ development GO:0048534 57 0.018
regulation of phosphorylation GO:0042325 147 0.018
cellular macromolecule localization GO:0070727 220 0.018
regulation of purine nucleotide metabolic process GO:1900542 62 0.018
Mouse
cellular response to oxygen containing compound GO:1901701 79 0.017
positive regulation of signaling GO:0023056 243 0.017
regulation of cell death GO:0010941 173 0.017
Mouse
positive regulation of hydrolase activity GO:0051345 78 0.017
Mouse
regulation of rho protein signal transduction GO:0035023 20 0.017
Mouse
eye morphogenesis GO:0048592 260 0.017
potassium ion transport GO:0006813 20 0.017
positive regulation of molecular function GO:0044093 136 0.017
Mouse
gtp catabolic process GO:0006184 72 0.017
Mouse
morphogenesis of a branching structure GO:0001763 45 0.017
regulation of cell cycle process GO:0010564 181 0.017
sex differentiation GO:0007548 81 0.017
ribonucleoside triphosphate metabolic process GO:0009199 119 0.017
Mouse
cellular component assembly involved in morphogenesis GO:0010927 151 0.017
regulation of hydrolase activity GO:0051336 97 0.017
Mouse
regulation of cellular component size GO:0032535 98 0.016
antimicrobial humoral response GO:0019730 99 0.016
guanosine containing compound catabolic process GO:1901069 74 0.016
Mouse
positive regulation of cell migration GO:0030335 2 0.016
response to bacterium GO:0009617 198 0.016
negative regulation of multicellular organismal process GO:0051241 142 0.016
cellular response to lipopolysaccharide GO:0071222 3 0.016
immune system development GO:0002520 57 0.016
amine metabolic process GO:0009308 12 0.016
positive regulation of nucleotide metabolic process GO:0045981 55 0.016
Mouse
digestive tract morphogenesis GO:0048546 127 0.016
circulatory system development GO:0072359 82 0.016
regulation of transport GO:0051049 181 0.016
chromosome segregation GO:0007059 157 0.016
positive regulation of phosphorus metabolic process GO:0010562 139 0.015
Mouse
respiratory system development GO:0060541 213 0.015
regulation of epithelial cell proliferation GO:0050678 4 0.015
tissue migration GO:0090130 155 0.015
regulation of cell projection organization GO:0031344 92 0.015
response to light stimulus GO:0009416 124 0.015
immune system process GO:0002376 347 0.015
negative regulation of cell differentiation GO:0045596 143 0.015
regulation of rho gtpase activity GO:0032319 20 0.015
Mouse
brain development GO:0007420 120 0.015
nuclear division GO:0000280 332 0.015
single organism cell adhesion GO:0098602 47 0.015
golgi organization GO:0007030 66 0.015
chemotaxis GO:0006935 249 0.015
polyol biosynthetic process GO:0046173 3 0.015
cellular response to dna damage stimulus GO:0006974 223 0.014
cellular response to molecule of bacterial origin GO:0071219 3 0.014
positive regulation of nucleotide catabolic process GO:0030813 46 0.014
Mouse
modification dependent macromolecule catabolic process GO:0043632 79 0.014
establishment of organelle localization GO:0051656 122 0.014
negative regulation of nitrogen compound metabolic process GO:0051172 265 0.014
regulation of purine nucleotide catabolic process GO:0033121 48 0.014
Mouse
nuclear transport GO:0051169 72 0.014
positive regulation of multicellular organismal process GO:0051240 143 0.014
proteolysis GO:0006508 192 0.014
regulation of peptidase activity GO:0052547 39 0.014
reproductive system development GO:0061458 74 0.014
forebrain development GO:0030900 2 0.014
cellular response to abiotic stimulus GO:0071214 58 0.014
photoreceptor cell differentiation GO:0046530 170 0.014
nucleoside phosphate metabolic process GO:0006753 162 0.013
Mouse
proteolysis involved in cellular protein catabolic process GO:0051603 83 0.013
humoral immune response GO:0006959 117 0.013
positive regulation of lipid storage GO:0010884 4 0.013
positive regulation of cytoskeleton organization GO:0051495 21 0.013
camera type eye development GO:0043010 4 0.013
regulation of programmed cell death GO:0043067 152 0.013
Mouse
positive regulation of response to stimulus GO:0048584 323 0.013
limb development GO:0060173 1 0.013
positive regulation of cellular amino acid metabolic process GO:0045764 0 0.013
syncytium formation by plasma membrane fusion GO:0000768 43 0.013
development of primary sexual characteristics GO:0045137 50 0.013
columnar cuboidal epithelial cell differentiation GO:0002065 256 0.013
regulation of neurogenesis GO:0050767 158 0.013
regulation of actin filament based process GO:0032970 42 0.013
cholesterol transport GO:0030301 2 0.013
receptor clustering GO:0043113 3 0.013
imaginal disc derived wing vein morphogenesis GO:0008586 44 0.013
growth GO:0040007 359 0.013
positive regulation of growth GO:0045927 75 0.013
response to uv GO:0009411 24 0.013
cellular response to growth factor stimulus GO:0071363 30 0.013
regulation of protein metabolic process GO:0051246 256 0.012
adult locomotory behavior GO:0008344 76 0.012
regulation of actin cytoskeleton organization GO:0032956 42 0.012
acid secretion GO:0046717 1 0.012
muscle structure development GO:0061061 224 0.012
intracellular protein transport GO:0006886 104 0.012
negative regulation of receptor activity GO:2000272 3 0.012
negative regulation of programmed cell death GO:0043069 72 0.012
Mouse
regulation of protein phosphorylation GO:0001932 64 0.012
regulation of transmembrane receptor protein serine threonine kinase signaling pathway GO:0090092 38 0.012
ameboidal type cell migration GO:0001667 151 0.012
centrosome cycle GO:0007098 137 0.012
positive regulation of developmental process GO:0051094 143 0.012
chondroitin sulfate proteoglycan metabolic process GO:0050654 3 0.012
establishment of cell polarity GO:0030010 40 0.012
cell cycle checkpoint GO:0000075 95 0.012
cellular macromolecular complex assembly GO:0034622 153 0.012
protein modification by small protein conjugation GO:0032446 79 0.012
head development GO:0060322 135 0.012
negative regulation of immune system process GO:0002683 50 0.012
negative regulation of cellular biosynthetic process GO:0031327 277 0.011
central nervous system development GO:0007417 201 0.011
single organism intracellular transport GO:1902582 207 0.011
protein ubiquitination GO:0016567 70 0.011
inorganic cation transmembrane transport GO:0098662 61 0.011
morphogenesis of an epithelium GO:0002009 276 0.011
stem cell proliferation GO:0072089 88 0.011
cell division GO:0051301 248 0.011
anterior posterior axis specification embryo GO:0008595 103 0.011
androgen metabolic process GO:0008209 1 0.011
mitotic nuclear division GO:0007067 213 0.011
protein complex biogenesis GO:0070271 201 0.011
inorganic anion transmembrane transport GO:0098661 14 0.011
response to organic cyclic compound GO:0014070 89 0.011
reproductive structure development GO:0048608 74 0.011
salivary gland morphogenesis GO:0007435 145 0.011
regulation of cell division GO:0051302 72 0.011
response to lipid GO:0033993 38 0.011
positive regulation of endopeptidase activity GO:0010950 26 0.011
protein transport GO:0015031 155 0.011
endosomal transport GO:0016197 44 0.011
retrograde transport endosome to golgi GO:0042147 3 0.011
neuromuscular junction development GO:0007528 149 0.011
regulation of lipid storage GO:0010883 22 0.011
sodium ion transport GO:0006814 22 0.011
regulation of cell cycle GO:0051726 291 0.010
negative regulation of catabolic process GO:0009895 36 0.010
negative regulation of nervous system development GO:0051961 92 0.010
mitotic spindle organization GO:0007052 220 0.010
microtubule based movement GO:0007018 51 0.010
negative regulation of protein metabolic process GO:0051248 85 0.010
positive regulation of transport GO:0051050 92 0.010
peptidyl threonine phosphorylation GO:0018107 2 0.010
synapse assembly GO:0007416 143 0.010
regulation of response to external stimulus GO:0032101 115 0.010
ubiquitin dependent protein catabolic process GO:0006511 78 0.010
cellular amine metabolic process GO:0044106 12 0.010
developmental growth GO:0048589 280 0.010
tripartite regional subdivision GO:0007351 103 0.010
regulation of notch signaling pathway GO:0008593 100 0.010
negative regulation of developmental process GO:0051093 201 0.010
carotenoid metabolic process GO:0016116 1 0.010
cell growth GO:0016049 108 0.010
positive regulation of rac gtpase activity GO:0032855 8 0.010

Graf disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in fly and predicted with the fly functional network.

Disease DO term ID Size Probability Func Analog Org
disease of anatomical entity DOID:7 0 0.097
sensory system disease DOID:0050155 0 0.014
nervous system disease DOID:863 0 0.014
eye and adnexa disease DOID:1492 0 0.012
eye disease DOID:5614 0 0.011
cancer DOID:162 0 0.011
Human
disease of cellular proliferation DOID:14566 0 0.011
Human
organ system cancer DOID:0050686 0 0.011
Human