Drosophila melanogaster

39 known processes

Rassf (Dmel_CG4656)

Ras association family member

(Aliases: Dmel\CG4656,RASSF,CG4656,dRASSF)

Rassf biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
negative regulation of nucleobase containing compound metabolic process GO:0045934 261 0.350
negative regulation of cellular biosynthetic process GO:0031327 277 0.148
phosphorylation GO:0016310 294 0.136
programmed cell death GO:0012501 257 0.121
organic cyclic compound catabolic process GO:1901361 168 0.101
negative regulation of nitrogen compound metabolic process GO:0051172 265 0.098
regulation of apoptotic process GO:0042981 130 0.097
purine nucleoside triphosphate metabolic process GO:0009144 119 0.094
regulation of phosphate metabolic process GO:0019220 210 0.093
negative regulation of transcription dna templated GO:0045892 237 0.088
multicellular organism growth GO:0035264 46 0.085
negative regulation of cellular macromolecule biosynthetic process GO:2000113 267 0.084
protein modification process GO:0036211 438 0.082
negative regulation of rna biosynthetic process GO:1902679 240 0.078
death GO:0016265 284 0.077
purine ribonucleoside triphosphate catabolic process GO:0009207 108 0.070
negative regulation of gene expression GO:0010629 387 0.068
growth GO:0040007 359 0.068
positive regulation of nitrogen compound metabolic process GO:0051173 354 0.068
negative regulation of macromolecule biosynthetic process GO:0010558 270 0.065
cellular protein modification process GO:0006464 438 0.061
ribonucleoside metabolic process GO:0009119 127 0.060
regulation of protein metabolic process GO:0051246 256 0.058
g2 dna damage checkpoint GO:0031572 69 0.057
heterocycle catabolic process GO:0046700 166 0.057
mitotic g2 m transition checkpoint GO:0044818 70 0.055
regionalization GO:0003002 416 0.055
negative regulation of signaling GO:0023057 219 0.055
negative regulation of cellular metabolic process GO:0031324 382 0.053
regulation of programmed cell death GO:0043067 152 0.052
cell motility GO:0048870 251 0.052
mitotic dna damage checkpoint GO:0044773 74 0.050
negative regulation of programmed cell death GO:0043069 72 0.049
small molecule metabolic process GO:0044281 305 0.049
developmental growth GO:0048589 280 0.048
nucleobase containing compound catabolic process GO:0034655 165 0.047
cell death GO:0008219 279 0.046
negative regulation of nucleic acid templated transcription GO:1903507 240 0.046
epithelium migration GO:0090132 148 0.046
regulation of cell cycle GO:0051726 291 0.043
regulation of organelle organization GO:0033043 196 0.043
nucleocytoplasmic transport GO:0006913 72 0.042
response to abiotic stimulus GO:0009628 341 0.041
neuron death GO:0070997 27 0.040
organonitrogen compound metabolic process GO:1901564 318 0.040
negative regulation of rna metabolic process GO:0051253 251 0.039
regulation of phosphorus metabolic process GO:0051174 210 0.038
positive regulation of growth GO:0045927 75 0.038
cell proliferation GO:0008283 299 0.037
regulation of nervous system development GO:0051960 248 0.036
chromosome organization GO:0051276 360 0.036
purine ribonucleoside triphosphate metabolic process GO:0009205 119 0.036
columnar cuboidal epithelial cell differentiation GO:0002065 256 0.036
regulation of cytoskeleton organization GO:0051493 89 0.035
aromatic compound catabolic process GO:0019439 166 0.035
cell type specific apoptotic process GO:0097285 38 0.035
organic substance catabolic process GO:1901575 308 0.033
negative regulation of biosynthetic process GO:0009890 277 0.033
apoptotic process GO:0006915 159 0.033
nucleobase containing small molecule metabolic process GO:0055086 174 0.032
ribonucleotide metabolic process GO:0009259 145 0.032
intracellular transport GO:0046907 228 0.032
nucleotide excision repair GO:0006289 8 0.032
wing disc morphogenesis GO:0007472 344 0.032
purine nucleoside triphosphate catabolic process GO:0009146 108 0.032
negative regulation of cell cycle process GO:0010948 109 0.031
nucleoside phosphate metabolic process GO:0006753 162 0.031
dna geometric change GO:0032392 16 0.030
transmembrane receptor protein tyrosine kinase signaling pathway GO:0007169 116 0.030
positive regulation of response to stimulus GO:0048584 323 0.030
nucleotide metabolic process GO:0009117 161 0.030
ribose phosphate metabolic process GO:0019693 145 0.030
positive regulation of biosynthetic process GO:0009891 316 0.030
nucleoside catabolic process GO:0009164 112 0.030
defense response GO:0006952 300 0.030
response to organic substance GO:0010033 284 0.029
tissue migration GO:0090130 155 0.029
positive regulation of cell communication GO:0010647 250 0.029
negative regulation of cell cycle phase transition GO:1901988 103 0.029
positive regulation of nucleic acid templated transcription GO:1903508 266 0.029
notch signaling pathway GO:0007219 120 0.028
cellular nitrogen compound catabolic process GO:0044270 165 0.028
catabolic process GO:0009056 409 0.028
mitotic dna integrity checkpoint GO:0044774 75 0.028
negative regulation of mitotic cell cycle GO:0045930 109 0.027
compound eye photoreceptor cell differentiation GO:0001751 140 0.027
cellular response to dna damage stimulus GO:0006974 223 0.027
embryonic morphogenesis GO:0048598 206 0.027
purine ribonucleoside monophosphate metabolic process GO:0009167 50 0.027
regulation of cell death GO:0010941 173 0.027
negative regulation of cell cycle GO:0045786 116 0.026
regulation of cellular amino acid metabolic process GO:0006521 0 0.026
localization of cell GO:0051674 257 0.025
purine containing compound metabolic process GO:0072521 155 0.025
ribonucleoside triphosphate catabolic process GO:0009203 108 0.025
imaginal disc derived wing morphogenesis GO:0007476 337 0.025
carbohydrate derivative metabolic process GO:1901135 217 0.025
regulation of mapk cascade GO:0043408 92 0.024
negative regulation of cell death GO:0060548 81 0.024
inositol lipid mediated signaling GO:0048017 4 0.024
epithelial cell development GO:0002064 274 0.023
positive regulation of developmental process GO:0051094 143 0.023
regulation of phosphorylation GO:0042325 147 0.022
purine ribonucleoside catabolic process GO:0046130 112 0.022
dna repair GO:0006281 54 0.022
columnar cuboidal epithelial cell development GO:0002066 249 0.022
dna duplex unwinding GO:0032508 16 0.022
mapk cascade GO:0000165 107 0.022
nucleotide catabolic process GO:0009166 109 0.021
compound eye morphogenesis GO:0001745 249 0.021
ribonucleotide catabolic process GO:0009261 109 0.021
cellular macromolecule localization GO:0070727 220 0.021
regulation of protein modification process GO:0031399 112 0.021
positive regulation of macromolecule biosynthetic process GO:0010557 283 0.021
epithelial cell migration GO:0010631 148 0.021
positive regulation of signaling GO:0023056 243 0.021
telencephalon development GO:0021537 2 0.021
non recombinational repair GO:0000726 7 0.021
cellular amino acid metabolic process GO:0006520 61 0.020
regulation of cell cycle process GO:0010564 181 0.020
mitotic g2 dna damage checkpoint GO:0007095 69 0.020
organophosphate catabolic process GO:0046434 112 0.020
developmental cell growth GO:0048588 52 0.020
recombinational repair GO:0000725 13 0.020
mitotic cell cycle checkpoint GO:0007093 88 0.020
lateral inhibition GO:0046331 206 0.020
positive regulation of macromolecule metabolic process GO:0010604 405 0.020
enzyme linked receptor protein signaling pathway GO:0007167 179 0.020
regulation of neuron death GO:1901214 26 0.019
embryo development ending in birth or egg hatching GO:0009792 152 0.019
purine ribonucleotide metabolic process GO:0009150 145 0.019
purine nucleotide catabolic process GO:0006195 109 0.019
establishment or maintenance of cell polarity GO:0007163 167 0.019
rna catabolic process GO:0006401 37 0.019
purine nucleoside metabolic process GO:0042278 127 0.019
positive regulation of rna metabolic process GO:0051254 271 0.019
neuron apoptotic process GO:0051402 17 0.018
nucleoside phosphate catabolic process GO:1901292 110 0.018
glycosyl compound catabolic process GO:1901658 112 0.018
eye photoreceptor cell differentiation GO:0001754 145 0.018
ribonucleoside catabolic process GO:0042454 112 0.018
chaeta development GO:0022416 97 0.017
positive regulation of cellular biosynthetic process GO:0031328 316 0.017
signal transduction by phosphorylation GO:0023014 107 0.017
establishment of ommatidial planar polarity GO:0042067 49 0.017
positive regulation of rna biosynthetic process GO:1902680 266 0.017
regulation of response to external stimulus GO:0032101 115 0.017
negative regulation of developmental process GO:0051093 201 0.017
gene silencing GO:0016458 138 0.017
regulation of intracellular signal transduction GO:1902531 236 0.017
peptidyl proline modification GO:0018208 3 0.017
anatomical structure homeostasis GO:0060249 97 0.017
chromatin modification GO:0016568 147 0.016
regulation of neuron apoptotic process GO:0043523 16 0.016
tube development GO:0035295 244 0.016
positive regulation of phosphate metabolic process GO:0045937 139 0.016
chromosome segregation GO:0007059 157 0.016
regulation of neurogenesis GO:0050767 158 0.016
establishment of localization in cell GO:0051649 402 0.016
negative regulation of cell communication GO:0010648 223 0.016
dna double strand break processing GO:0000729 3 0.016
organophosphate metabolic process GO:0019637 195 0.016
purine ribonucleotide catabolic process GO:0009154 109 0.016
positive regulation of multicellular organismal process GO:0051240 143 0.016
regulation of growth GO:0040008 233 0.016
transcription from rna polymerase ii promoter GO:0006366 368 0.016
regulation of anatomical structure size GO:0090066 163 0.016
nuclear transport GO:0051169 72 0.016
homeostatic process GO:0042592 199 0.016
phosphatidylinositol mediated signaling GO:0048015 4 0.016
tissue morphogenesis GO:0048729 297 0.015
establishment of tissue polarity GO:0007164 87 0.015
protein phosphorylation GO:0006468 169 0.015
positive regulation of cellular component organization GO:0051130 156 0.015
purine nucleotide metabolic process GO:0006163 146 0.015
oxoacid metabolic process GO:0043436 103 0.014
regulation of immune system process GO:0002682 176 0.014
ribonucleoside triphosphate metabolic process GO:0009199 119 0.014
photoreceptor cell differentiation GO:0046530 170 0.014
memory GO:0007613 94 0.014
cellular ketone metabolic process GO:0042180 24 0.014
ribonucleoside monophosphate catabolic process GO:0009158 39 0.014
negative regulation of apoptotic process GO:0043066 63 0.014
body morphogenesis GO:0010171 2 0.014
peptidyl amino acid modification GO:0018193 105 0.014
amine metabolic process GO:0009308 12 0.014
regulation of cellular component biogenesis GO:0044087 201 0.013
organonitrogen compound catabolic process GO:1901565 128 0.013
negative regulation of protein metabolic process GO:0051248 85 0.013
regulation of response to stress GO:0080134 200 0.013
peptidyl tyrosine phosphorylation GO:0018108 24 0.013
gtp catabolic process GO:0006184 72 0.013
nucleoside triphosphate metabolic process GO:0009141 120 0.013
regulation of cellular catabolic process GO:0031329 157 0.013
endocytosis GO:0006897 310 0.013
gland development GO:0048732 191 0.013
regulation of cellular amine metabolic process GO:0033238 3 0.013
negative regulation of response to stimulus GO:0048585 258 0.013
mitotic cell cycle phase transition GO:0044772 138 0.013
segmentation GO:0035282 207 0.013
regulation of cellular component size GO:0032535 98 0.013
purine containing compound catabolic process GO:0072523 112 0.013
dna metabolic process GO:0006259 227 0.013
response to other organism GO:0051707 293 0.012
eye morphogenesis GO:0048592 260 0.012
regulation of transcription from rna polymerase ii promoter GO:0006357 378 0.012
positive regulation of transcription dna templated GO:0045893 266 0.012
vesicle mediated transport GO:0016192 381 0.012
negative regulation of cellular protein metabolic process GO:0032269 85 0.012
positive regulation of phosphorus metabolic process GO:0010562 139 0.012
lymph gland development GO:0048542 28 0.012
response to monosaccharide GO:0034284 4 0.012
positive regulation of phosphorylation GO:0042327 87 0.012
regulation of cellular response to stress GO:0080135 89 0.012
positive regulation of protein metabolic process GO:0051247 128 0.012
carboxylic acid metabolic process GO:0019752 92 0.012
cellular response to abiotic stimulus GO:0071214 58 0.012
neuron recognition GO:0008038 101 0.012
single organism biosynthetic process GO:0044711 206 0.012
cell migration GO:0016477 238 0.012
intracellular mrna localization GO:0008298 66 0.011
nucleoside triphosphate catabolic process GO:0009143 108 0.011
morphogenesis of a polarized epithelium GO:0001738 93 0.011
cytoplasmic transport GO:0016482 130 0.011
regulation of establishment of protein localization GO:0070201 61 0.011
protein hydroxylation GO:0018126 1 0.011
locomotory behavior GO:0007626 176 0.011
double strand break repair via homologous recombination GO:0000724 13 0.011
regulation of meiosis GO:0040020 3 0.011
macromolecule catabolic process GO:0009057 161 0.011
protein localization GO:0008104 284 0.011
purine nucleoside catabolic process GO:0006152 112 0.011
actin filament polymerization GO:0030041 27 0.011
dna conformation change GO:0071103 105 0.011
glycosyl compound metabolic process GO:1901657 127 0.011
cellular amine metabolic process GO:0044106 12 0.011
regulation of developmental growth GO:0048638 174 0.011
response to nitrogen compound GO:1901698 90 0.011
response to growth factor GO:0070848 31 0.011
guanosine containing compound metabolic process GO:1901068 74 0.011
regulation of ras protein signal transduction GO:0046578 93 0.011
protein transport GO:0015031 155 0.010
chromatin silencing GO:0006342 76 0.010
nucleoside monophosphate metabolic process GO:0009123 52 0.010
negative regulation of signal transduction GO:0009968 206 0.010
immune effector process GO:0002252 98 0.010
compound eye development GO:0048749 307 0.010
connective tissue development GO:0061448 3 0.010
rho protein signal transduction GO:0007266 14 0.010
stem cell differentiation GO:0048863 117 0.010
single organism catabolic process GO:0044712 228 0.010
negative regulation of nervous system development GO:0051961 92 0.010
nuclear export GO:0051168 24 0.010
cellular macromolecule catabolic process GO:0044265 136 0.010
regulation of cell proliferation GO:0042127 163 0.010
response to heat GO:0009408 63 0.010
regulation of molecular function GO:0065009 217 0.010
small gtpase mediated signal transduction GO:0007264 88 0.010
regulation of cellular protein metabolic process GO:0032268 243 0.010

Rassf disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in fly and predicted with the fly functional network.

Disease DO term ID Size Probability Func Analog Org
cancer DOID:162 0 0.035
disease of cellular proliferation DOID:14566 0 0.035
organ system cancer DOID:0050686 0 0.030
disease of anatomical entity DOID:7 0 0.021