Drosophila melanogaster

67 known processes

AP-1sigma (Dmel_CG5864)

CG5864 gene product from transcript CG5864-RA

(Aliases: cg5864,AP-1[sigma],Dmel\CG5864,sigma1,CG5864)

AP-1sigma biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
regulation of cell differentiation GO:0045595 302 0.295
small molecule metabolic process GO:0044281 305 0.253
protein heterooligomerization GO:0051291 4 0.178
muscle cell differentiation GO:0042692 103 0.156
regulation of anatomical structure morphogenesis GO:0022603 242 0.152
small gtpase mediated signal transduction GO:0007264 88 0.148
cellular amine metabolic process GO:0044106 12 0.148
ras protein signal transduction GO:0007265 88 0.143
immune system process GO:0002376 347 0.135
protein complex assembly GO:0006461 200 0.128
regulation of immune system process GO:0002682 176 0.122
endocytosis GO:0006897 310 0.115
respiratory system development GO:0060541 213 0.100
cytoskeleton dependent cytokinesis GO:0061640 81 0.096
positive regulation of response to stimulus GO:0048584 323 0.093
response to other organism GO:0051707 293 0.089
Human
carbohydrate derivative biosynthetic process GO:1901137 85 0.084
regulation of multicellular organismal development GO:2000026 414 0.081
response to external biotic stimulus GO:0043207 293 0.080
Human
oxoacid metabolic process GO:0043436 103 0.079
amine metabolic process GO:0009308 12 0.078
regulation of cell development GO:0060284 215 0.076
establishment of localization in cell GO:0051649 402 0.070
organonitrogen compound metabolic process GO:1901564 318 0.070
regulation of anatomical structure size GO:0090066 163 0.068
carbohydrate derivative metabolic process GO:1901135 217 0.065
cellular amino acid metabolic process GO:0006520 61 0.061
synaptic transmission GO:0007268 288 0.058
positive regulation of nucleic acid templated transcription GO:1903508 266 0.054
taxis GO:0042330 304 0.054
cell cycle arrest GO:0007050 4 0.054
ameboidal type cell migration GO:0001667 151 0.048
regulation of phosphate metabolic process GO:0019220 210 0.047
ribonucleoside metabolic process GO:0009119 127 0.046
regulation of small gtpase mediated signal transduction GO:0051056 93 0.046
regulation of localization GO:0032879 275 0.046
single organism biosynthetic process GO:0044711 206 0.044
cell cycle checkpoint GO:0000075 95 0.044
cellular macromolecule catabolic process GO:0044265 136 0.043
vesicle mediated transport GO:0016192 381 0.042
organic acid metabolic process GO:0006082 103 0.041
carboxylic acid metabolic process GO:0019752 92 0.040
extrinsic apoptotic signaling pathway GO:0097191 1 0.038
positive regulation of cellular biosynthetic process GO:0031328 316 0.037
organic substance catabolic process GO:1901575 308 0.036
negative regulation of cellular metabolic process GO:0031324 382 0.036
nucleoside phosphate metabolic process GO:0006753 162 0.035
compound eye development GO:0048749 307 0.035
heterocycle catabolic process GO:0046700 166 0.035
positive regulation of immune response GO:0050778 63 0.034
immune response GO:0006955 246 0.034
cell death GO:0008219 279 0.034
positive regulation of cell differentiation GO:0045597 64 0.033
apoptotic process GO:0006915 159 0.033
striated muscle cell differentiation GO:0051146 90 0.031
regulation of cellular amine metabolic process GO:0033238 3 0.031
regulation of cellular component biogenesis GO:0044087 201 0.030
gland development GO:0048732 191 0.030
muscle structure development GO:0061061 224 0.030
mapk cascade GO:0000165 107 0.030
negative regulation of developmental process GO:0051093 201 0.029
meiotic cell cycle process GO:1903046 132 0.028
dna metabolic process GO:0006259 227 0.027
regulation of cell death GO:0010941 173 0.027
protein modification process GO:0036211 438 0.027
positive regulation of macromolecule biosynthetic process GO:0010557 283 0.027
negative regulation of cell death GO:0060548 81 0.027
cellular response to organic substance GO:0071310 132 0.027
cellular macromolecule localization GO:0070727 220 0.027
regulation of mapk cascade GO:0043408 92 0.026
regulation of neurogenesis GO:0050767 158 0.026
intracellular signal transduction GO:0035556 300 0.025
regulation of ras protein signal transduction GO:0046578 93 0.025
regulation of phosphorus metabolic process GO:0051174 210 0.025
adult behavior GO:0030534 137 0.025
nucleotide metabolic process GO:0009117 161 0.024
membrane organization GO:0061024 112 0.024
nucleobase containing compound catabolic process GO:0034655 165 0.024
phosphorylation GO:0016310 294 0.024
nucleoside triphosphate metabolic process GO:0009141 120 0.024
response to biotic stimulus GO:0009607 294 0.024
Human
embryonic morphogenesis GO:0048598 206 0.024
protein acylation GO:0043543 42 0.024
defense response to bacterium GO:0042742 178 0.024
negative regulation of cell differentiation GO:0045596 143 0.023
positive regulation of phosphorus metabolic process GO:0010562 139 0.023
organic substance transport GO:0071702 257 0.023
purine ribonucleoside metabolic process GO:0046128 127 0.023
regulation of immune response GO:0050776 118 0.023
defense response to other organism GO:0098542 225 0.023
aromatic compound catabolic process GO:0019439 166 0.023
protein localization GO:0008104 284 0.022
macromolecular complex assembly GO:0065003 256 0.022
regulation of multi organism process GO:0043900 131 0.022
negative regulation of programmed cell death GO:0043069 72 0.022
regulation of neuron projection development GO:0010975 69 0.022
programmed cell death GO:0012501 257 0.022
positive regulation of cellular amine metabolic process GO:0033240 0 0.022
cellular protein modification process GO:0006464 438 0.021
positive regulation of transport GO:0051050 92 0.021
regulation of cellular ketone metabolic process GO:0010565 3 0.021
signal transduction by phosphorylation GO:0023014 107 0.020
death GO:0016265 284 0.020
cellular ketone metabolic process GO:0042180 24 0.020
purine ribonucleoside catabolic process GO:0046130 112 0.019
single organism catabolic process GO:0044712 228 0.019
response to organic substance GO:0010033 284 0.019
mitotic cell cycle checkpoint GO:0007093 88 0.019
macromolecule catabolic process GO:0009057 161 0.019
regulation of locomotion GO:0040012 42 0.019
catabolic process GO:0009056 409 0.019
regulation of cellular localization GO:0060341 136 0.019
innate immune response GO:0045087 144 0.019
purine ribonucleoside triphosphate metabolic process GO:0009205 119 0.019
ribose phosphate metabolic process GO:0019693 145 0.019
stress activated mapk cascade GO:0051403 52 0.018
cellular catabolic process GO:0044248 372 0.018
regulation of cell morphogenesis GO:0022604 163 0.018
positive regulation of neuron projection regeneration GO:0070572 3 0.018
purine nucleotide metabolic process GO:0006163 146 0.018
organophosphate metabolic process GO:0019637 195 0.018
intracellular transport GO:0046907 228 0.018
phagocytosis GO:0006909 215 0.018
cell cell signaling involved in cell fate commitment GO:0045168 210 0.018
negative regulation of signaling GO:0023057 219 0.018
regulation of apoptotic process GO:0042981 130 0.017
stress activated protein kinase signaling cascade GO:0031098 55 0.017
cellular nitrogen compound catabolic process GO:0044270 165 0.017
peptidyl threonine phosphorylation GO:0018107 2 0.017
organophosphate catabolic process GO:0046434 112 0.017
forebrain development GO:0030900 2 0.016
blood circulation GO:0008015 26 0.016
regulation of programmed cell death GO:0043067 152 0.016
learning or memory GO:0007611 141 0.016
response to radiation GO:0009314 155 0.016
cellular response to chemical stimulus GO:0070887 199 0.016
regulation of rac protein signal transduction GO:0035020 3 0.016
purine nucleoside metabolic process GO:0042278 127 0.016
single organism behavior GO:0044708 391 0.016
response to lipopolysaccharide GO:0032496 4 0.016
rac protein signal transduction GO:0016601 3 0.016
cellular response to external stimulus GO:0071496 66 0.015
regulation of defense response GO:0031347 102 0.015
regulation of nervous system development GO:0051960 248 0.015
nucleoside triphosphate catabolic process GO:0009143 108 0.015
regulation of cellular response to stress GO:0080135 89 0.015
positive regulation of immune system process GO:0002684 68 0.015
intermediate filament based process GO:0045103 1 0.015
regulation of cell shape GO:0008360 113 0.014
regulation of response to stress GO:0080134 200 0.014
response to oxygen containing compound GO:1901700 200 0.014
nucleosome assembly GO:0006334 35 0.014
carbohydrate derivative catabolic process GO:1901136 118 0.014
peptidyl lysine acetylation GO:0018394 39 0.014
developmental maturation GO:0021700 172 0.014
striated muscle cell development GO:0055002 50 0.014
regulation of embryonic cell shape GO:0016476 30 0.014
purine ribonucleoside triphosphate catabolic process GO:0009207 108 0.014
chromatin modification GO:0016568 147 0.014
purine nucleoside catabolic process GO:0006152 112 0.013
response to extracellular stimulus GO:0009991 116 0.013
positive regulation of nucleobase containing compound metabolic process GO:0045935 332 0.013
stem cell differentiation GO:0048863 117 0.013
protein complex biogenesis GO:0070271 201 0.013
regulation of cellular amino acid metabolic process GO:0006521 0 0.013
response to nitrogen compound GO:1901698 90 0.013
purine containing compound metabolic process GO:0072521 155 0.013
positive regulation of cell development GO:0010720 61 0.013
negative regulation of cellular protein metabolic process GO:0032269 85 0.013
jnk cascade GO:0007254 50 0.013
establishment of protein localization GO:0045184 163 0.013
response to abiotic stimulus GO:0009628 341 0.013
defense response GO:0006952 300 0.012
regulation of response to external stimulus GO:0032101 115 0.012
positive regulation of cell motility GO:2000147 3 0.012
positive regulation of nitrogen compound metabolic process GO:0051173 354 0.012
negative regulation of nervous system development GO:0051961 92 0.012
positive regulation of phosphate metabolic process GO:0045937 139 0.012
glycoprotein biosynthetic process GO:0009101 41 0.012
detection of external stimulus GO:0009581 66 0.012
cellular response to extracellular stimulus GO:0031668 64 0.012
carbohydrate metabolic process GO:0005975 82 0.012
developmental programmed cell death GO:0010623 138 0.012
dephosphorylation GO:0016311 51 0.012
single organism intracellular transport GO:1902582 207 0.012
regulation of cellular component size GO:0032535 98 0.012
positive regulation of molecular function GO:0044093 136 0.012
positive regulation of reactive oxygen species metabolic process GO:2000379 0 0.011
establishment of tissue polarity GO:0007164 87 0.011
connective tissue development GO:0061448 3 0.011
cell motility GO:0048870 251 0.011
embryo development ending in birth or egg hatching GO:0009792 152 0.011
secretion by cell GO:0032940 101 0.011
regulation of cellular protein metabolic process GO:0032268 243 0.011
positive regulation of gene expression GO:0010628 290 0.011
positive regulation of signal transduction GO:0009967 223 0.011
response to bacterium GO:0009617 198 0.011
regulation of nucleotide metabolic process GO:0006140 62 0.011
detection of stimulus GO:0051606 156 0.011
positive regulation of defense response GO:0031349 59 0.011
positive regulation of signaling GO:0023056 243 0.011
regulation of innate immune response GO:0045088 71 0.011
negative regulation of biosynthetic process GO:0009890 277 0.011
cellular protein localization GO:0034613 160 0.011
ovarian follicle cell development GO:0030707 248 0.011
purine containing compound catabolic process GO:0072523 112 0.011
ribonucleotide metabolic process GO:0009259 145 0.011
stem cell development GO:0048864 79 0.010
lateral inhibition GO:0046331 206 0.010
embryonic development via the syncytial blastoderm GO:0001700 148 0.010
regulation of phosphorylation GO:0042325 147 0.010
positive regulation of developmental process GO:0051094 143 0.010
stem cell proliferation GO:0072089 88 0.010
negative regulation of apoptotic process GO:0043066 63 0.010
actin filament based process GO:0030029 220 0.010
regulation of hemocyte proliferation GO:0035206 37 0.010

AP-1sigma disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in fly and predicted with the fly functional network.

Disease DO term ID Size Probability Func Analog Org