Drosophila melanogaster

131 known processes

dik (Dmel_CG7098)

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(Aliases: HL-XIV,Ada3,Dmel\CG7098,dAda3,DADA3,CG7098)

dik biological process predictions


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Biological process GO term ID Process size Probability Func Analog Org
protein acetylation GO:0006473 39 1.000
internal protein amino acid acetylation GO:0006475 38 0.998
histone modification GO:0016570 106 0.995
chromatin modification GO:0016568 147 0.995
chromosome organization GO:0051276 360 0.987
internal peptidyl lysine acetylation GO:0018393 38 0.985
protein acylation GO:0043543 42 0.984
peptidyl lysine acetylation GO:0018394 39 0.975
histone acetylation GO:0016573 38 0.968
chromatin organization GO:0006325 207 0.966
peptidyl lysine modification GO:0018205 57 0.939
histone h4 acetylation GO:0043967 13 0.932
chromatin remodeling GO:0006338 72 0.879
histone h3 acetylation GO:0043966 11 0.862
covalent chromatin modification GO:0016569 106 0.813
histone h3 k9 acetylation GO:0043970 3 0.479
regulation of histone acetylation GO:0035065 7 0.401
cellular protein modification process GO:0006464 438 0.393
positive regulation of cellular biosynthetic process GO:0031328 316 0.379
positive regulation of macromolecule biosynthetic process GO:0010557 283 0.363
positive regulation of nucleobase containing compound metabolic process GO:0045935 332 0.342
positive regulation of nitrogen compound metabolic process GO:0051173 354 0.342
positive regulation of histone acetylation GO:0035066 3 0.330
regulation of multicellular organismal development GO:2000026 414 0.302
protein modification process GO:0036211 438 0.295
positive regulation of molecular function GO:0044093 136 0.261
cellular macromolecular complex assembly GO:0034622 153 0.231
regulation of catabolic process GO:0009894 170 0.230
positive regulation of proteolysis GO:0045862 52 0.221
body morphogenesis GO:0010171 2 0.219
cell fate specification GO:0001708 71 0.212
digestive tract morphogenesis GO:0048546 127 0.207
localization of cell GO:0051674 257 0.206
macromolecular complex assembly GO:0065003 256 0.205
cellular ketone metabolic process GO:0042180 24 0.194
positive regulation of catabolic process GO:0009896 105 0.191
regulation of transcription from rna polymerase ii promoter GO:0006357 378 0.188
positive regulation of cellular catabolic process GO:0031331 95 0.187
positive regulation of protein metabolic process GO:0051247 128 0.183
ubiquitin dependent protein catabolic process GO:0006511 78 0.172
organophosphate metabolic process GO:0019637 195 0.171
regulation of cellular catabolic process GO:0031329 157 0.170
catabolic process GO:0009056 409 0.170
protein catabolic process GO:0030163 101 0.154
regulation of protein acetylation GO:1901983 7 0.150
positive regulation of rna biosynthetic process GO:1902680 266 0.146
purine nucleotide catabolic process GO:0006195 109 0.145
regulation of cellular ketone metabolic process GO:0010565 3 0.139
cellular amine metabolic process GO:0044106 12 0.136
organonitrogen compound biosynthetic process GO:1901566 117 0.130
cellular response to organic substance GO:0071310 132 0.129
protein complex biogenesis GO:0070271 201 0.129
cellular response to chemical stimulus GO:0070887 199 0.128
organic substance catabolic process GO:1901575 308 0.123
histone h4 k16 acetylation GO:0043984 4 0.119
positive regulation of catalytic activity GO:0043085 118 0.118
negative regulation of biosynthetic process GO:0009890 277 0.116
negative regulation of macromolecule biosynthetic process GO:0010558 270 0.115
regulation of molecular function GO:0065009 217 0.106
single organism biosynthetic process GO:0044711 206 0.104
positive regulation of transcription dna templated GO:0045893 266 0.102
negative regulation of nucleobase containing compound metabolic process GO:0045934 261 0.102
response to other organism GO:0051707 293 0.101
cellular catabolic process GO:0044248 372 0.099
protein complex assembly GO:0006461 200 0.097
positive regulation of phosphate metabolic process GO:0045937 139 0.097
regulation of cellular amino acid metabolic process GO:0006521 0 0.091
cellular response to dna damage stimulus GO:0006974 223 0.090
response to organic substance GO:0010033 284 0.089
positive regulation of hydrolase activity GO:0051345 78 0.088
negative regulation of cellular biosynthetic process GO:0031327 277 0.088
regulation of anatomical structure size GO:0090066 163 0.087
proteolysis involved in cellular protein catabolic process GO:0051603 83 0.082
negative regulation of cellular metabolic process GO:0031324 382 0.079
regulation of cell cycle phase transition GO:1901987 130 0.078
small molecule metabolic process GO:0044281 305 0.077
carbohydrate derivative metabolic process GO:1901135 217 0.076
protein palmitoylation GO:0018345 2 0.075
malpighian tubule development GO:0072002 64 0.074
cellular protein catabolic process GO:0044257 83 0.073
ribonucleoside triphosphate metabolic process GO:0009199 119 0.072
positive regulation of biosynthetic process GO:0009891 316 0.071
negative regulation of gene expression epigenetic GO:0045814 77 0.070
ribonucleotide catabolic process GO:0009261 109 0.069
protein modification by small protein conjugation or removal GO:0070647 106 0.068
cell proliferation GO:0008283 299 0.067
male gamete generation GO:0048232 201 0.066
regulation of cell shape GO:0008360 113 0.066
modification dependent protein catabolic process GO:0019941 78 0.066
positive regulation of ras gtpase activity GO:0032320 36 0.064
regulation of hydrolase activity GO:0051336 97 0.062
proteolysis GO:0006508 192 0.062
regulation of histone modification GO:0031056 20 0.057
organonitrogen compound metabolic process GO:1901564 318 0.057
positive regulation of phosphorus metabolic process GO:0010562 139 0.055
organelle assembly GO:0070925 198 0.055
positive regulation of macromolecule metabolic process GO:0010604 405 0.053
response to endogenous stimulus GO:0009719 119 0.053
tube morphogenesis GO:0035239 191 0.053
positive regulation of cellular component organization GO:0051130 156 0.053
nucleoside triphosphate catabolic process GO:0009143 108 0.050
positive regulation of transcription from rna polymerase ii promoter GO:0045944 204 0.049
negative regulation of rna metabolic process GO:0051253 251 0.049
cell motility GO:0048870 251 0.049
nucleoside metabolic process GO:0009116 127 0.048
regulation of nucleoside metabolic process GO:0009118 50 0.047
organelle fusion GO:0048284 46 0.046
regulation of phosphorus metabolic process GO:0051174 210 0.044
regulation of phosphate metabolic process GO:0019220 210 0.044
regulation of dna metabolic process GO:0051052 34 0.044
regulation of protein modification process GO:0031399 112 0.043
regulation of ras gtpase activity GO:0032318 38 0.043
embryo development ending in birth or egg hatching GO:0009792 152 0.042
protein modification by small protein conjugation GO:0032446 79 0.042
regulation of catalytic activity GO:0050790 185 0.042
positive regulation of nucleic acid templated transcription GO:1903508 266 0.042
growth GO:0040007 359 0.042
axis specification GO:0009798 167 0.042
purine containing compound metabolic process GO:0072521 155 0.042
developmental pigmentation GO:0048066 68 0.042
immune response GO:0006955 246 0.041
neuroblast proliferation GO:0007405 74 0.041
positive regulation of multicellular organismal process GO:0051240 143 0.040
muscle structure development GO:0061061 224 0.039
response to biotic stimulus GO:0009607 294 0.039
regulation of chromosome organization GO:0033044 64 0.039
humoral immune response GO:0006959 117 0.039
eye antennal disc development GO:0035214 60 0.039
histone deubiquitination GO:0016578 8 0.039
regulation of cell cycle GO:0051726 291 0.039
positive regulation of organelle organization GO:0010638 65 0.038
regulation of response to stress GO:0080134 200 0.038
determination of adult lifespan GO:0008340 137 0.038
regulation of cell cycle process GO:0010564 181 0.038
chromatin silencing GO:0006342 76 0.037
amine metabolic process GO:0009308 12 0.037
cellular response to growth factor stimulus GO:0071363 30 0.037
transcription from rna polymerase ii promoter GO:0006366 368 0.037
negative regulation of transcription from rna polymerase ii promoter GO:0000122 119 0.037
purine nucleotide metabolic process GO:0006163 146 0.037
gland development GO:0048732 191 0.037
cell cycle phase transition GO:0044770 140 0.036
positive regulation of response to external stimulus GO:0032103 44 0.036
digestive tract development GO:0048565 149 0.036
regulation of chromatin organization GO:1902275 32 0.035
retina development in camera type eye GO:0060041 4 0.035
regulation of mitotic cell cycle phase transition GO:1901990 130 0.035
purine ribonucleotide catabolic process GO:0009154 109 0.035
positive regulation of developmental process GO:0051094 143 0.035
mitotic cell cycle embryonic GO:0045448 38 0.035
peptidyl amino acid modification GO:0018193 105 0.035
negative regulation of transcription dna templated GO:0045892 237 0.034
cellular macromolecule catabolic process GO:0044265 136 0.034
g2 dna damage checkpoint GO:0031572 69 0.034
macromolecule catabolic process GO:0009057 161 0.034
modification dependent macromolecule catabolic process GO:0043632 79 0.033
guanosine containing compound catabolic process GO:1901069 74 0.033
regulation of gene expression epigenetic GO:0040029 128 0.033
regulation of protein metabolic process GO:0051246 256 0.032
notch signaling pathway GO:0007219 120 0.031
morphogenesis of a branching epithelium GO:0061138 45 0.031
secondary metabolic process GO:0019748 75 0.031
enzyme linked receptor protein signaling pathway GO:0007167 179 0.031
ribonucleotide metabolic process GO:0009259 145 0.031
positive regulation of jun kinase activity GO:0043507 4 0.030
regulation of cell differentiation GO:0045595 302 0.030
retina morphogenesis in camera type eye GO:0060042 2 0.030
positive regulation of protein modification process GO:0031401 58 0.030
posttranscriptional regulation of gene expression GO:0010608 145 0.030
positive regulation of cellular protein metabolic process GO:0032270 118 0.030
regulation of cellular amine metabolic process GO:0033238 3 0.030
regulation of anatomical structure morphogenesis GO:0022603 242 0.030
mitotic cell cycle phase transition GO:0044772 138 0.029
cell migration GO:0016477 238 0.029
protein ubiquitination GO:0016567 70 0.029
defense response to gram negative bacterium GO:0050829 94 0.029
eye photoreceptor cell differentiation GO:0001754 145 0.028
negative regulation of nitrogen compound metabolic process GO:0051172 265 0.028
purine nucleoside catabolic process GO:0006152 112 0.028
organophosphate biosynthetic process GO:0090407 46 0.028
ribonucleoside metabolic process GO:0009119 127 0.027
purine nucleoside metabolic process GO:0042278 127 0.027
renal tubule morphogenesis GO:0061333 44 0.027
regulation of cellular component biogenesis GO:0044087 201 0.027
single organism behavior GO:0044708 391 0.027
regulation of synapse structure and activity GO:0050803 128 0.027
chromatin assembly or disassembly GO:0006333 52 0.026
single organism catabolic process GO:0044712 228 0.026
regulation of nervous system development GO:0051960 248 0.026
regulation of nucleotide metabolic process GO:0006140 62 0.026
regulation of cellular component size GO:0032535 98 0.026
purine ribonucleotide metabolic process GO:0009150 145 0.026
regulation of proteolysis GO:0030162 87 0.026
renal system development GO:0072001 72 0.025
negative regulation of developmental process GO:0051093 201 0.025
regulation of small gtpase mediated signal transduction GO:0051056 93 0.025
dendrite morphogenesis GO:0048813 199 0.025
response to abiotic stimulus GO:0009628 341 0.025
regulation of mitotic cell cycle GO:0007346 190 0.025
regulation of ras protein signal transduction GO:0046578 93 0.025
multi organism behavior GO:0051705 175 0.024
nucleotide catabolic process GO:0009166 109 0.024
regulation of embryonic cell shape GO:0016476 30 0.024
cellular response to endogenous stimulus GO:0071495 80 0.024
head involution GO:0008258 35 0.024
camera type eye development GO:0043010 4 0.024
lateral inhibition GO:0046331 206 0.024
positive regulation of protein kinase activity GO:0045860 25 0.024
positive regulation of phosphorylation GO:0042327 87 0.023
negative regulation of response to stimulus GO:0048585 258 0.023
ras protein signal transduction GO:0007265 88 0.023
small gtpase mediated signal transduction GO:0007264 88 0.023
positive regulation of cell cycle GO:0045787 43 0.023
positive regulation of nucleotide metabolic process GO:0045981 55 0.023
regulation of developmental growth GO:0048638 174 0.023
positive regulation of gene expression GO:0010628 290 0.022
carboxylic acid metabolic process GO:0019752 92 0.022
spermatogenesis GO:0007283 200 0.022
embryonic morphogenesis GO:0048598 206 0.021
morphogenesis of embryonic epithelium GO:0016331 94 0.021
regulation of defense response GO:0031347 102 0.021
phagocytosis GO:0006909 215 0.020
positive regulation of peptidase activity GO:0010952 29 0.020
regulation of notch signaling pathway GO:0008593 100 0.020
positive regulation of gtpase activity GO:0043547 43 0.020
calcium ion homeostasis GO:0055074 23 0.020
establishment of localization in cell GO:0051649 402 0.020
eye morphogenesis GO:0048592 260 0.020
negative regulation of signaling GO:0023057 219 0.020
nucleobase containing compound catabolic process GO:0034655 165 0.020
developmental growth GO:0048589 280 0.020
negative regulation of rna biosynthetic process GO:1902679 240 0.020
dna metabolic process GO:0006259 227 0.019
positive regulation of purine nucleotide metabolic process GO:1900544 55 0.019
cellular homeostasis GO:0019725 80 0.019
response to lipopolysaccharide GO:0032496 4 0.019
regulation of nucleotide catabolic process GO:0030811 48 0.019
glycerophospholipid metabolic process GO:0006650 23 0.018
cell division GO:0051301 248 0.018
carbohydrate derivative catabolic process GO:1901136 118 0.018
extrinsic apoptotic signaling pathway GO:0097191 1 0.018
muscle cell differentiation GO:0042692 103 0.018
camera type eye morphogenesis GO:0048593 2 0.018
positive regulation of proteasomal protein catabolic process GO:1901800 20 0.018
negative regulation of cell cycle process GO:0010948 109 0.018
negative regulation of dna dependent dna replication GO:2000104 2 0.018
protein dna complex assembly GO:0065004 63 0.018
autophagy GO:0006914 108 0.018
proteasomal protein catabolic process GO:0010498 59 0.017
regulation of protein catabolic process GO:0042176 55 0.017
homeostatic process GO:0042592 199 0.017
glycosyl compound catabolic process GO:1901658 112 0.017
cell cycle checkpoint GO:0000075 95 0.017
negative regulation of mitotic cell cycle GO:0045930 109 0.017
regulation of cellular protein metabolic process GO:0032268 243 0.017
nucleocytoplasmic transport GO:0006913 72 0.017
meiosis i GO:0007127 59 0.017
response to oxygen containing compound GO:1901700 200 0.017
negative regulation of cell cycle GO:0045786 116 0.017
ribose phosphate metabolic process GO:0019693 145 0.016
protein maturation GO:0051604 71 0.016
dna damage checkpoint GO:0000077 78 0.016
branching involved in open tracheal system development GO:0060446 45 0.016
positive regulation of nucleotide catabolic process GO:0030813 46 0.016
cellular amino acid metabolic process GO:0006520 61 0.015
nucleoside triphosphate metabolic process GO:0009141 120 0.015
digestive system development GO:0055123 149 0.015
lipid metabolic process GO:0006629 121 0.015
glycerolipid metabolic process GO:0046486 34 0.015
positive regulation of protein catabolic process GO:0045732 34 0.015
peptidyl threonine phosphorylation GO:0018107 2 0.015
negative regulation of cell cycle phase transition GO:1901988 103 0.015
glycosyl compound metabolic process GO:1901657 127 0.015
response to alcohol GO:0097305 95 0.015
ribonucleoside catabolic process GO:0042454 112 0.015
cellular lipid metabolic process GO:0044255 83 0.015
columnar cuboidal epithelial cell differentiation GO:0002065 256 0.014
chemosensory behavior GO:0007635 106 0.014
regulation of immune system process GO:0002682 176 0.014
negative regulation of gene expression GO:0010629 387 0.014
salivary gland histolysis GO:0035070 88 0.014
gastrulation GO:0007369 70 0.014
regulation of chromatin modification GO:1903308 28 0.014
gene silencing GO:0016458 138 0.014
purine ribonucleoside triphosphate catabolic process GO:0009207 108 0.014
female meiotic division GO:0007143 70 0.014
spindle organization GO:0007051 253 0.014
purine nucleoside triphosphate catabolic process GO:0009146 108 0.014
male meiosis GO:0007140 52 0.014
regulation of purine nucleotide catabolic process GO:0033121 48 0.014
metal ion transport GO:0030001 74 0.014
purine ribonucleoside catabolic process GO:0046130 112 0.014
negative regulation of cellular component organization GO:0051129 108 0.013
regulation of gtp catabolic process GO:0033124 44 0.013
compound eye development GO:0048749 307 0.013
cellular carbohydrate metabolic process GO:0044262 22 0.013
ribonucleoside triphosphate catabolic process GO:0009203 108 0.013
positive regulation of cellular amino acid metabolic process GO:0045764 0 0.013
cellular protein complex assembly GO:0043623 71 0.013
positive regulation of mitotic cell cycle GO:0045931 34 0.013
nucleoside phosphate metabolic process GO:0006753 162 0.013
regulation of jun kinase activity GO:0043506 8 0.013
photoreceptor cell differentiation GO:0046530 170 0.013
regulation of embryonic development GO:0045995 68 0.013
positive regulation of protein phosphorylation GO:0001934 34 0.013
multicellular organismal aging GO:0010259 140 0.012
regulation of cell morphogenesis GO:0022604 163 0.012
stem cell division GO:0017145 69 0.012
actin cytoskeleton organization GO:0030036 206 0.012
immune system process GO:0002376 347 0.012
positive regulation of proteolysis involved in cellular protein catabolic process GO:1903052 24 0.012
protein processing GO:0016485 68 0.012
nucleotide metabolic process GO:0009117 161 0.012
gtp metabolic process GO:0046039 72 0.012
eye photoreceptor cell development GO:0042462 81 0.011
positive regulation of rna metabolic process GO:0051254 271 0.011
positive regulation of transport GO:0051050 92 0.011
aromatic compound catabolic process GO:0019439 166 0.011
organic cyclic compound catabolic process GO:1901361 168 0.011
negative regulation of developmental growth GO:0048640 64 0.011
positive regulation of purine nucleotide catabolic process GO:0033123 46 0.011
carbohydrate metabolic process GO:0005975 82 0.011
regulation of metal ion transport GO:0010959 15 0.011
regulation of cellular response to stress GO:0080135 89 0.011
positive regulation of growth GO:0045927 75 0.011
regulation of hemocyte proliferation GO:0035206 37 0.010
hindgut development GO:0061525 58 0.010
endocytosis GO:0006897 310 0.010
macroautophagy GO:0016236 42 0.010
regulation of epithelial cell differentiation GO:0030856 4 0.010
zymogen activation GO:0031638 20 0.010
regulation of localization GO:0032879 275 0.010

dik disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in fly and predicted with the fly functional network.

Disease DO term ID Size Probability Func Analog Org
disease of anatomical entity DOID:7 0 0.034
sensory system disease DOID:0050155 0 0.016
eye and adnexa disease DOID:1492 0 0.016
nervous system disease DOID:863 0 0.016
disease of cellular proliferation DOID:14566 0 0.012