Drosophila melanogaster

19 known processes

CAP (Dmel_CG18408)

CG18408 gene product from transcript CG18408-RI

(Aliases: rexin,CG18408,CG18409,cap,CG3451,DCAP,Dmel\CG18408,CAP/Vinexin,Rexin)

CAP biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
sensory perception of sound GO:0007605 56 0.964
sensory perception of mechanical stimulus GO:0050954 72 0.729
sensory perception GO:0007600 196 0.609
cilium assembly GO:0042384 38 0.447
neurological system process GO:0050877 358 0.423
axon cargo transport GO:0008088 29 0.209
body morphogenesis GO:0010171 2 0.202
eye morphogenesis GO:0048592 260 0.163
negative regulation of macromolecule biosynthetic process GO:0010558 270 0.157
Mouse
muscle structure development GO:0061061 224 0.152
germarium derived egg chamber formation GO:0007293 101 0.149
learning or memory GO:0007611 141 0.146
centrosome cycle GO:0007098 137 0.143
sensory organ morphogenesis GO:0090596 260 0.111
nucleobase containing compound catabolic process GO:0034655 165 0.105
positive regulation of response to stimulus GO:0048584 323 0.105
Mouse
centrosome organization GO:0051297 163 0.103
cilium organization GO:0044782 41 0.103
protein complex biogenesis GO:0070271 201 0.096
cellular macromolecule localization GO:0070727 220 0.093
Mouse
microtubule based movement GO:0007018 51 0.091
dendrite development GO:0016358 204 0.088
ribonucleoside catabolic process GO:0042454 112 0.088
cell projection assembly GO:0030031 94 0.086
centrosome duplication GO:0051298 121 0.082
wnt signaling pathway GO:0016055 98 0.082
carbohydrate derivative metabolic process GO:1901135 217 0.082
single organism catabolic process GO:0044712 228 0.082
negative regulation of gene expression GO:0010629 387 0.082
Mouse
catabolic process GO:0009056 409 0.081
ribonucleoside triphosphate metabolic process GO:0009199 119 0.080
organelle fission GO:0048285 340 0.075
negative regulation of cellular macromolecule biosynthetic process GO:2000113 267 0.074
Mouse
adherens junction organization GO:0034332 27 0.073
Mouse
purine nucleoside triphosphate catabolic process GO:0009146 108 0.073
purine nucleotide catabolic process GO:0006195 109 0.073
regulation of wnt signaling pathway GO:0030111 68 0.070
organelle assembly GO:0070925 198 0.069
exocrine system development GO:0035272 162 0.069
cell junction organization GO:0034330 57 0.068
Mouse
embryonic development via the syncytial blastoderm GO:0001700 148 0.067
glycosyl compound catabolic process GO:1901658 112 0.066
heterocycle catabolic process GO:0046700 166 0.064
ribonucleotide metabolic process GO:0009259 145 0.062
vesicle mediated transport GO:0016192 381 0.062
macromolecular complex assembly GO:0065003 256 0.060
positive regulation of phosphate metabolic process GO:0045937 139 0.060
Mouse
negative regulation of cellular metabolic process GO:0031324 382 0.060
Mouse
ribonucleotide catabolic process GO:0009261 109 0.058
establishment of localization in cell GO:0051649 402 0.058
cell junction assembly GO:0034329 42 0.057
Mouse
nucleoside triphosphate catabolic process GO:0009143 108 0.056
organic substance catabolic process GO:1901575 308 0.056
male courtship behavior GO:0008049 63 0.054
cell death GO:0008219 279 0.054
retrograde axon cargo transport GO:0008090 9 0.054
regulation of hydrolase activity GO:0051336 97 0.052
regulation of localization GO:0032879 275 0.051
Mouse
purine ribonucleoside triphosphate catabolic process GO:0009207 108 0.050
response to oxidative stress GO:0006979 86 0.050
aromatic compound catabolic process GO:0019439 166 0.050
cell growth GO:0016049 108 0.050
developmental programmed cell death GO:0010623 138 0.049
cellular protein localization GO:0034613 160 0.049
Mouse
head development GO:0060322 135 0.048
mitotic nuclear division GO:0007067 213 0.048
cellular component assembly involved in morphogenesis GO:0010927 151 0.047
regulation of phosphorylation GO:0042325 147 0.047
Mouse
cellular response to external stimulus GO:0071496 66 0.047
purine ribonucleoside triphosphate metabolic process GO:0009205 119 0.046
phagocytosis GO:0006909 215 0.046
adherens junction assembly GO:0034333 11 0.046
Mouse
regulation of intracellular signal transduction GO:1902531 236 0.046
Mouse
small molecule metabolic process GO:0044281 305 0.045
microtubule organizing center organization GO:0031023 168 0.045
purine nucleotide metabolic process GO:0006163 146 0.044
nucleotide metabolic process GO:0009117 161 0.044
regulation of epithelial cell proliferation GO:0050678 4 0.044
cell cell junction organization GO:0045216 55 0.043
Mouse
glycosyl compound metabolic process GO:1901657 127 0.043
regulation of cellular catabolic process GO:0031329 157 0.042
positive regulation of purine nucleotide metabolic process GO:1900544 55 0.042
death GO:0016265 284 0.039
nucleoside phosphate catabolic process GO:1901292 110 0.039
rho protein signal transduction GO:0007266 14 0.039
compound eye development GO:0048749 307 0.039
regulation of cell proliferation GO:0042127 163 0.039
ribonucleoside triphosphate catabolic process GO:0009203 108 0.037
negative regulation of nucleic acid templated transcription GO:1903507 240 0.037
Mouse
cell proliferation GO:0008283 299 0.037
cellular catabolic process GO:0044248 372 0.036
regulation of catalytic activity GO:0050790 185 0.036
regulation of nucleotide catabolic process GO:0030811 48 0.036
imaginal disc derived wing morphogenesis GO:0007476 337 0.036
purine ribonucleotide metabolic process GO:0009150 145 0.036
endocytosis GO:0006897 310 0.036
multi organism reproductive behavior GO:0044705 121 0.035
appendage development GO:0048736 401 0.035
positive regulation of intracellular signal transduction GO:1902533 116 0.035
Mouse
purine containing compound metabolic process GO:0072521 155 0.034
eye development GO:0001654 323 0.034
spermatogenesis GO:0007283 200 0.034
organic cyclic compound catabolic process GO:1901361 168 0.034
carbohydrate derivative catabolic process GO:1901136 118 0.034
purine nucleoside triphosphate metabolic process GO:0009144 119 0.034
mating GO:0007618 120 0.034
regulation of cellular ketone metabolic process GO:0010565 3 0.033
gland morphogenesis GO:0022612 145 0.033
nucleoside metabolic process GO:0009116 127 0.033
positive regulation of phosphorus metabolic process GO:0010562 139 0.032
Mouse
positive regulation of cellular amino acid metabolic process GO:0045764 0 0.032
learning GO:0007612 75 0.031
salivary gland development GO:0007431 162 0.031
gliogenesis GO:0042063 80 0.030
cellular nitrogen compound catabolic process GO:0044270 165 0.030
purine ribonucleoside catabolic process GO:0046130 112 0.030
neuron maturation GO:0042551 31 0.030
organonitrogen compound catabolic process GO:1901565 128 0.030
spermatid development GO:0007286 98 0.029
response to wounding GO:0009611 94 0.029
salivary gland cell autophagic cell death GO:0035071 83 0.029
autophagic cell death GO:0048102 83 0.029
cell cell junction assembly GO:0007043 38 0.029
cell recognition GO:0008037 102 0.029
intracellular signal transduction GO:0035556 300 0.029
Mouse
appendage morphogenesis GO:0035107 397 0.029
organophosphate metabolic process GO:0019637 195 0.029
purine nucleoside catabolic process GO:0006152 112 0.028
regulation of catabolic process GO:0009894 170 0.028
cell maturation GO:0048469 144 0.028
organonitrogen compound metabolic process GO:1901564 318 0.028
extracellular structure organization GO:0043062 46 0.028
positive regulation of multicellular organismal process GO:0051240 143 0.027
purine containing compound catabolic process GO:0072523 112 0.027
positive regulation of signal transduction GO:0009967 223 0.027
Mouse
positive regulation of phosphorylation GO:0042327 87 0.027
Mouse
reproductive behavior GO:0019098 122 0.027
transcription from rna polymerase ii promoter GO:0006366 368 0.026
Mouse
positive regulation of catalytic activity GO:0043085 118 0.026
oxoacid metabolic process GO:0043436 103 0.026
epithelial cell development GO:0002064 274 0.026
mitotic spindle organization GO:0007052 220 0.026
tissue death GO:0016271 102 0.026
nucleotide catabolic process GO:0009166 109 0.025
innate immune response GO:0045087 144 0.025
protein complex assembly GO:0006461 200 0.025
organophosphate catabolic process GO:0046434 112 0.025
determination of adult lifespan GO:0008340 137 0.025
positive regulation of molecular function GO:0044093 136 0.025
cytoskeleton dependent intracellular transport GO:0030705 44 0.025
kidney development GO:0001822 3 0.025
nucleoside phosphate metabolic process GO:0006753 162 0.024
monocarboxylic acid transport GO:0015718 3 0.023
regulation of protein metabolic process GO:0051246 256 0.023
somatic muscle development GO:0007525 66 0.023
positive regulation of signaling GO:0023056 243 0.023
Mouse
post embryonic appendage morphogenesis GO:0035120 385 0.023
maintenance of location GO:0051235 73 0.023
positive regulation of nucleobase containing compound metabolic process GO:0045935 332 0.023
notch signaling pathway GO:0007219 120 0.023
positive regulation of cell proliferation GO:0008284 47 0.023
regulation of phosphate metabolic process GO:0019220 210 0.022
Mouse
multi multicellular organism process GO:0044706 123 0.022
ribonucleoside metabolic process GO:0009119 127 0.022
proteolysis GO:0006508 192 0.022
mating behavior GO:0007617 106 0.022
positive regulation of hydrolase activity GO:0051345 78 0.022
actin filament organization GO:0007015 126 0.022
Mouse
regulation of molecular function GO:0065009 217 0.022
regulation of mapk cascade GO:0043408 92 0.022
Mouse
protein modification by small protein conjugation GO:0032446 79 0.021
regulation of phosphorus metabolic process GO:0051174 210 0.021
Mouse
multicellular organismal aging GO:0010259 140 0.021
intracellular transport GO:0046907 228 0.021
cellular macromolecular complex assembly GO:0034622 153 0.021
positive regulation of protein modification process GO:0031401 58 0.021
macromolecule catabolic process GO:0009057 161 0.020
regulation of cell death GO:0010941 173 0.020
guanosine containing compound metabolic process GO:1901068 74 0.020
protein localization GO:0008104 284 0.020
Mouse
salivary gland morphogenesis GO:0007435 145 0.020
intracellular protein transport GO:0006886 104 0.020
microtubule bundle formation GO:0001578 27 0.020
cell adhesion GO:0007155 136 0.020
Mouse
positive regulation of macromolecule biosynthetic process GO:0010557 283 0.020
Mouse
negative regulation of rna metabolic process GO:0051253 251 0.020
Mouse
regulation of microtubule based process GO:0032886 49 0.020
circadian rhythm GO:0007623 105 0.020
cell division GO:0051301 248 0.020
negative regulation of transcription dna templated GO:0045892 237 0.019
Mouse
protein modification process GO:0036211 438 0.019
peptidyl tyrosine phosphorylation GO:0018108 24 0.019
ion transmembrane transport GO:0034220 122 0.019
transmembrane transport GO:0055085 139 0.019
histolysis GO:0007559 102 0.019
cilium morphogenesis GO:0060271 39 0.019
salivary gland histolysis GO:0035070 88 0.019
immune response GO:0006955 246 0.019
mrna metabolic process GO:0016071 124 0.019
regulation of cellular protein metabolic process GO:0032268 243 0.019
adult locomotory behavior GO:0008344 76 0.019
spermatid differentiation GO:0048515 114 0.018
gtp catabolic process GO:0006184 72 0.018
wound healing GO:0042060 75 0.018
positive regulation of purine nucleotide catabolic process GO:0033123 46 0.018
growth GO:0040007 359 0.018
response to abiotic stimulus GO:0009628 341 0.018
muscle organ development GO:0007517 127 0.018
developmental growth GO:0048589 280 0.018
immune system process GO:0002376 347 0.018
cognition GO:0050890 141 0.018
negative regulation of nucleobase containing compound metabolic process GO:0045934 261 0.018
Mouse
hindbrain development GO:0030902 2 0.018
forebrain development GO:0030900 2 0.018
regulation of developmental growth GO:0048638 174 0.017
response to bacterium GO:0009617 198 0.017
organic acid metabolic process GO:0006082 103 0.017
positive regulation of cellular catabolic process GO:0031331 95 0.017
peptidyl tyrosine modification GO:0018212 24 0.017
positive regulation of growth GO:0045927 75 0.017
apoptotic process GO:0006915 159 0.017
regulation of cytoskeleton organization GO:0051493 89 0.017
succinate transport GO:0015744 2 0.016
carboxylic acid metabolic process GO:0019752 92 0.016
brain development GO:0007420 120 0.016
purine ribonucleoside metabolic process GO:0046128 127 0.016
microtubule based transport GO:0010970 42 0.016
compound eye morphogenesis GO:0001745 249 0.016
gene silencing GO:0016458 138 0.016
regulation of tube architecture open tracheal system GO:0035152 68 0.016
regulation of organelle organization GO:0033043 196 0.016
extrinsic apoptotic signaling pathway GO:0097191 1 0.016
neuron remodeling GO:0016322 29 0.016
positive regulation of mapk cascade GO:0043410 63 0.016
Mouse
single organism cell adhesion GO:0098602 47 0.016
regulation of notch signaling pathway GO:0008593 100 0.016
morphogenesis of an epithelium GO:0002009 276 0.015
negative regulation of cell proliferation GO:0008285 69 0.015
cellular protein modification process GO:0006464 438 0.015
cation transmembrane transport GO:0098655 88 0.015
muscle attachment GO:0016203 36 0.015
axon development GO:0061564 297 0.015
neural precursor cell proliferation GO:0061351 75 0.015
androgen metabolic process GO:0008209 1 0.015
regulation of gtpase activity GO:0043087 44 0.015
regulation of nervous system development GO:0051960 248 0.015
nuclear division GO:0000280 332 0.015
nucleoside triphosphate metabolic process GO:0009141 120 0.015
amine metabolic process GO:0009308 12 0.015
positive regulation of catabolic process GO:0009896 105 0.015
positive regulation of protein metabolic process GO:0051247 128 0.014
camera type eye development GO:0043010 4 0.014
developmental maturation GO:0021700 172 0.014
negative regulation of cell communication GO:0010648 223 0.014
cellularization GO:0007349 90 0.014
regulation of nucleoside metabolic process GO:0009118 50 0.014
positive regulation of cellular protein metabolic process GO:0032270 118 0.014
rna processing GO:0006396 147 0.014
ras protein signal transduction GO:0007265 88 0.014
microtubule cytoskeleton organization involved in mitosis GO:1902850 52 0.014
mrna processing GO:0006397 104 0.014
response to lipopolysaccharide GO:0032496 4 0.014
purine nucleoside metabolic process GO:0042278 127 0.014
positive regulation of cell communication GO:0010647 250 0.014
Mouse
guanosine containing compound catabolic process GO:1901069 74 0.014
regulation of mitotic cell cycle phase transition GO:1901990 130 0.014
regulation of purine nucleotide catabolic process GO:0033121 48 0.014
protein maturation GO:0051604 71 0.014
programmed cell death GO:0012501 257 0.014
response to monosaccharide GO:0034284 4 0.013
dendrite morphogenesis GO:0048813 199 0.013
homeostatic process GO:0042592 199 0.013
regulation of protein serine threonine kinase activity GO:0071900 25 0.013
positive regulation of gtpase activity GO:0043547 43 0.013
regulation of cell development GO:0060284 215 0.013
regulation of cellular amino acid metabolic process GO:0006521 0 0.013
cell migration GO:0016477 238 0.013
olfactory learning GO:0008355 56 0.013
rhythmic process GO:0048511 106 0.013
positive regulation of nucleoside metabolic process GO:0045979 47 0.013
regulation of body fluid levels GO:0050878 14 0.013
regulation of programmed cell death GO:0043067 152 0.013
detection of stimulus GO:0051606 156 0.013
signal transduction by phosphorylation GO:0023014 107 0.013
Mouse
locomotory behavior GO:0007626 176 0.013
cellular response to mechanical stimulus GO:0071260 2 0.013
organ growth GO:0035265 56 0.013
axoneme assembly GO:0035082 18 0.013
anatomical structure homeostasis GO:0060249 97 0.013
imaginal disc derived wing margin morphogenesis GO:0008587 41 0.012
regulation of cellular amine metabolic process GO:0033238 3 0.012
neuron death GO:0070997 27 0.012
male gamete generation GO:0048232 201 0.012
ribose phosphate metabolic process GO:0019693 145 0.012
cellular macromolecule catabolic process GO:0044265 136 0.012
negative regulation of nervous system development GO:0051961 92 0.012
small gtpase mediated signal transduction GO:0007264 88 0.012
regulation of neuron death GO:1901214 26 0.012
single organismal cell cell adhesion GO:0016337 45 0.012
regulation of multicellular organismal development GO:2000026 414 0.012
negative regulation of sequestering of calcium ion GO:0051283 2 0.012
positive regulation of nucleotide catabolic process GO:0030813 46 0.012
regulation of microtubule cytoskeleton organization GO:0070507 41 0.012
positive regulation of transferase activity GO:0051347 26 0.012
regulation of protein modification process GO:0031399 112 0.011
regulation of gene expression epigenetic GO:0040029 128 0.011
cellular homeostasis GO:0019725 80 0.011
cranial nerve development GO:0021545 1 0.011
positive regulation of defense response GO:0031349 59 0.011
positive regulation of cellular amine metabolic process GO:0033240 0 0.011
cellular protein complex assembly GO:0043623 71 0.011
protein ubiquitination GO:0016567 70 0.011
positive regulation of cellular component organization GO:0051130 156 0.011
Mouse
biological adhesion GO:0022610 138 0.011
Mouse
cellular ketone metabolic process GO:0042180 24 0.011
negative regulation of developmental process GO:0051093 201 0.011
gland development GO:0048732 191 0.011
actin cytoskeleton organization GO:0030036 206 0.011
Mouse
organelle localization GO:0051640 148 0.011
tissue morphogenesis GO:0048729 297 0.011
molting cycle GO:0042303 56 0.011
cellular amine metabolic process GO:0044106 12 0.011
convergent extension GO:0060026 2 0.011
substrate adhesion dependent cell spreading GO:0034446 2 0.011
maintenance of protein location in cell GO:0032507 26 0.011
localization of cell GO:0051674 257 0.011
cellular response to starvation GO:0009267 61 0.011
digestive tract development GO:0048565 149 0.010
protein catabolic process GO:0030163 101 0.010
regulation of circadian rhythm GO:0042752 49 0.010
respiratory system development GO:0060541 213 0.010
cellular response to organic substance GO:0071310 132 0.010
Mouse
regulation of nucleotide metabolic process GO:0006140 62 0.010
regulation of behavior GO:0050795 75 0.010
apposition of dorsal and ventral imaginal disc derived wing surfaces GO:0007475 15 0.010

CAP disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in fly and predicted with the fly functional network.

Disease DO term ID Size Probability Func Analog Org
musculoskeletal system disease DOID:17 0 0.131
disease of anatomical entity DOID:7 0 0.131
cardiovascular system disease DOID:1287 0 0.129
muscular disease DOID:0080000 0 0.044
muscle tissue disease DOID:66 0 0.044
myopathy DOID:423 0 0.033
cardiomyopathy DOID:0050700 0 0.014
heart disease DOID:114 0 0.014