Drosophila melanogaster

47 known processes

Indy (Dmel_CG3979)

I'm not dead yet

(Aliases: drIndy,INDY,indy,Dmel\CG3979,anon-EST:fe3A7,anon-WO0172774.70,CG3979,BEST:LP01220)

Indy biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
multicellular organismal aging GO:0010259 140 0.928
determination of adult lifespan GO:0008340 137 0.876
aging GO:0007568 143 0.714
cellular response to peptide GO:1901653 28 0.544
polysaccharide biosynthetic process GO:0000271 7 0.434
response to organic substance GO:0010033 284 0.361
oxoacid metabolic process GO:0043436 103 0.298
regulation of cell differentiation GO:0045595 302 0.295
response to oxidative stress GO:0006979 86 0.241
organic acid metabolic process GO:0006082 103 0.237
single organism biosynthetic process GO:0044711 206 0.237
small molecule metabolic process GO:0044281 305 0.235
proteolysis GO:0006508 192 0.232
regionalization GO:0003002 416 0.225
catabolic process GO:0009056 409 0.224
negative regulation of cell communication GO:0010648 223 0.224
enzyme linked receptor protein signaling pathway GO:0007167 179 0.223
transmembrane receptor protein tyrosine kinase signaling pathway GO:0007169 116 0.187
negative regulation of growth GO:0045926 84 0.179
organic substance transport GO:0071702 257 0.172
negative regulation of cellular metabolic process GO:0031324 382 0.168
carboxylic acid metabolic process GO:0019752 92 0.160
cellular response to organonitrogen compound GO:0071417 36 0.155
negative regulation of signaling GO:0023057 219 0.154
negative regulation of signal transduction GO:0009968 206 0.152
intracellular signal transduction GO:0035556 300 0.149
negative regulation of response to stimulus GO:0048585 258 0.144
cellular catabolic process GO:0044248 372 0.134
single organism cell adhesion GO:0098602 47 0.130
regulation of nervous system development GO:0051960 248 0.125
dorsal ventral pattern formation GO:0009953 133 0.119
single organism carbohydrate metabolic process GO:0044723 72 0.119
regulation of developmental growth GO:0048638 174 0.119
Worm
response to bacterium GO:0009617 198 0.117
regulation of immune response GO:0050776 118 0.113
positive regulation of biosynthetic process GO:0009891 316 0.112
positive regulation of cell migration GO:0030335 2 0.106
response to oxygen containing compound GO:1901700 200 0.104
regulation of localization GO:0032879 275 0.102
response to lipopolysaccharide GO:0032496 4 0.099
carboxylic acid transport GO:0046942 18 0.096
larval development GO:0002164 104 0.096
ion transmembrane transport GO:0034220 122 0.094
transcription from rna polymerase ii promoter GO:0006366 368 0.091
growth GO:0040007 359 0.090
Worm
lipid metabolic process GO:0006629 121 0.089
Worm
organonitrogen compound metabolic process GO:1901564 318 0.085
inositol lipid mediated signaling GO:0048017 4 0.084
regulation of multicellular organismal development GO:2000026 414 0.083
regulation of immune system process GO:0002682 176 0.079
appendage development GO:0048736 401 0.079
cellular response to peptide hormone stimulus GO:0071375 28 0.079
response to abiotic stimulus GO:0009628 341 0.078
regulation of cellular amino acid metabolic process GO:0006521 0 0.077
single organism catabolic process GO:0044712 228 0.075
positive regulation of cell motility GO:2000147 3 0.071
response to topologically incorrect protein GO:0035966 10 0.070
positive regulation of cell differentiation GO:0045597 64 0.070
lipopolysaccharide mediated signaling pathway GO:0031663 1 0.070
bmp signaling pathway GO:0030509 27 0.067
response to organonitrogen compound GO:0010243 75 0.066
regulation of transcription from rna polymerase ii promoter GO:0006357 378 0.066
insulin receptor signaling pathway GO:0008286 25 0.065
positive regulation of lipid metabolic process GO:0045834 4 0.065
regulation of defense response GO:0031347 102 0.064
response to wounding GO:0009611 94 0.064
response to monosaccharide GO:0034284 4 0.063
transmembrane transport GO:0055085 139 0.063
positive regulation of immune system process GO:0002684 68 0.062
organophosphate metabolic process GO:0019637 195 0.062
monocarboxylic acid transport GO:0015718 3 0.062
response to external biotic stimulus GO:0043207 293 0.062
positive regulation of response to stimulus GO:0048584 323 0.061
response to growth factor GO:0070848 31 0.061
cellular response to endogenous stimulus GO:0071495 80 0.060
response to other organism GO:0051707 293 0.058
cellular response to chemical stimulus GO:0070887 199 0.057
metal ion transport GO:0030001 74 0.057
Zebrafish Worm
immune response regulating signaling pathway GO:0002764 2 0.056
endocytosis GO:0006897 310 0.055
monocarboxylic acid metabolic process GO:0032787 29 0.054
response to endogenous stimulus GO:0009719 119 0.054
organic substance catabolic process GO:1901575 308 0.053
regulation of growth GO:0040008 233 0.053
Worm
cell motility GO:0048870 251 0.052
regulation of cellular localization GO:0060341 136 0.052
er nucleus signaling pathway GO:0006984 9 0.051
intercellular bridge organization GO:0043063 14 0.051
cation transport GO:0006812 110 0.051
Zebrafish Worm
cellular amino acid metabolic process GO:0006520 61 0.051
positive regulation of developmental process GO:0051094 143 0.050
Worm
extracellular structure organization GO:0043062 46 0.049
dna damage checkpoint GO:0000077 78 0.048
carbohydrate metabolic process GO:0005975 82 0.047
germline ring canal formation GO:0030725 13 0.047
establishment of localization in cell GO:0051649 402 0.046
wound healing GO:0042060 75 0.045
negative regulation of multicellular organismal process GO:0051241 142 0.045
organic acid transport GO:0015849 18 0.045
transmembrane receptor protein serine threonine kinase signaling pathway GO:0007178 65 0.044
cell death GO:0008219 279 0.044
cellular response to hormone stimulus GO:0032870 44 0.044
positive regulation of calcium ion transport GO:0051928 4 0.043
germarium derived egg chamber formation GO:0007293 101 0.043
positive regulation of signaling GO:0023056 243 0.042
adult behavior GO:0030534 137 0.042
connective tissue development GO:0061448 3 0.042
response to hormone GO:0009725 45 0.041
nucleotide metabolic process GO:0009117 161 0.041
regulation of organ growth GO:0046620 42 0.041
phosphatidylinositol 3 kinase signaling GO:0014065 4 0.040
response to alcohol GO:0097305 95 0.039
regulation of neuron differentiation GO:0045664 103 0.039
response to peptide hormone GO:0043434 29 0.039
regulation of cell adhesion GO:0030155 27 0.038
oxidation reduction process GO:0055114 123 0.038
tube development GO:0035295 244 0.038
regulation of neuron death GO:1901214 26 0.037
olfactory learning GO:0008355 56 0.037
positive regulation of signal transduction GO:0009967 223 0.037
organelle fission GO:0048285 340 0.037
chemotaxis GO:0006935 249 0.037
response to peptide GO:1901652 29 0.037
positive regulation of rna metabolic process GO:0051254 271 0.036
cellular response to dna damage stimulus GO:0006974 223 0.036
polysaccharide metabolic process GO:0005976 11 0.036
imaginal disc derived appendage morphogenesis GO:0035114 395 0.035
central nervous system development GO:0007417 201 0.035
regulation of phosphorus metabolic process GO:0051174 210 0.034
nucleobase containing small molecule metabolic process GO:0055086 174 0.034
ion transport GO:0006811 145 0.034
learning GO:0007612 75 0.033
localization of cell GO:0051674 257 0.033
associative learning GO:0008306 65 0.032
response to nitrogen compound GO:1901698 90 0.032
body morphogenesis GO:0010171 2 0.032
regulation of anatomical structure morphogenesis GO:0022603 242 0.032
cellular response to oxygen containing compound GO:1901701 79 0.032
immune response activating signal transduction GO:0002757 2 0.032
positive regulation of cellular response to insulin stimulus GO:1900078 4 0.031
single organism intracellular transport GO:1902582 207 0.031
phosphatidylinositol mediated signaling GO:0048015 4 0.031
cellular response to nitrogen compound GO:1901699 51 0.030
cellular response to insulin stimulus GO:0032869 28 0.030
somatic muscle development GO:0007525 66 0.030
appendage morphogenesis GO:0035107 397 0.030
proteasome mediated ubiquitin dependent protein catabolic process GO:0043161 54 0.030
single organismal cell cell adhesion GO:0016337 45 0.029
negative regulation of protein metabolic process GO:0051248 85 0.029
regulation of phosphatidylinositol 3 kinase signaling GO:0014066 4 0.029
mrna catabolic process GO:0006402 33 0.029
regulation of cellular ketone metabolic process GO:0010565 3 0.029
regulation of response to stress GO:0080134 200 0.029
nitrogen compound transport GO:0071705 85 0.029
response to insulin GO:0032868 29 0.028
positive regulation of nitrogen compound metabolic process GO:0051173 354 0.028
cellular response to growth factor stimulus GO:0071363 30 0.028
positive regulation of phosphate metabolic process GO:0045937 139 0.028
extrinsic apoptotic signaling pathway GO:0097191 1 0.028
vesicle mediated transport GO:0016192 381 0.028
cellular response to organic substance GO:0071310 132 0.028
cell migration GO:0016477 238 0.028
carbohydrate derivative metabolic process GO:1901135 217 0.028
negative regulation of neuron death GO:1901215 18 0.028
regulation of apoptotic process GO:0042981 130 0.028
defense response to other organism GO:0098542 225 0.028
nucleoside phosphate metabolic process GO:0006753 162 0.028
regulation of cellular component size GO:0032535 98 0.027
negative regulation of macromolecule biosynthetic process GO:0010558 270 0.027
response to biotic stimulus GO:0009607 294 0.027
cellular ketone metabolic process GO:0042180 24 0.026
lipid modification GO:0030258 24 0.026
positive regulation of nervous system development GO:0051962 69 0.026
eye development GO:0001654 323 0.025
imaginal disc derived appendage development GO:0048737 399 0.025
regulation of programmed cell death GO:0043067 152 0.025
dna replication GO:0006260 48 0.025
positive regulation of immune response GO:0050778 63 0.025
purine nucleotide metabolic process GO:0006163 146 0.025
molting cycle GO:0042303 56 0.025
regulation of transport GO:0051049 181 0.025
positive regulation of macromolecule metabolic process GO:0010604 405 0.025
macromolecule catabolic process GO:0009057 161 0.024
regulation of carbohydrate metabolic process GO:0006109 10 0.024
energy derivation by oxidation of organic compounds GO:0015980 32 0.024
spinal cord dorsal ventral patterning GO:0021513 1 0.024
neuron death GO:0070997 27 0.024
peptide metabolic process GO:0006518 80 0.024
biological adhesion GO:0022610 138 0.024
imaginal disc derived wing morphogenesis GO:0007476 337 0.024
post embryonic appendage morphogenesis GO:0035120 385 0.024
regulation of cellular catabolic process GO:0031329 157 0.024
regulation of intracellular signal transduction GO:1902531 236 0.023
secretion GO:0046903 109 0.023
homeostatic process GO:0042592 199 0.023
regulation of phosphorylation GO:0042325 147 0.023
sulfur compound metabolic process GO:0006790 59 0.023
response to extracellular stimulus GO:0009991 116 0.023
g2 dna damage checkpoint GO:0031572 69 0.023
negative regulation of cellular protein metabolic process GO:0032269 85 0.023
positive regulation of cellular biosynthetic process GO:0031328 316 0.023
intracellular transport GO:0046907 228 0.022
innate immune response activating signal transduction GO:0002758 2 0.022
death GO:0016265 284 0.022
columnar cuboidal epithelial cell development GO:0002066 249 0.022
regulation of cellular component biogenesis GO:0044087 201 0.022
cytoplasmic transport GO:0016482 130 0.022
dna integrity checkpoint GO:0031570 81 0.021
inorganic cation transmembrane transport GO:0098662 61 0.021
Zebrafish Worm
purine containing compound metabolic process GO:0072521 155 0.021
regulation of phosphate metabolic process GO:0019220 210 0.021
positive regulation of nucleic acid templated transcription GO:1903508 266 0.021
purine ribonucleotide metabolic process GO:0009150 145 0.021
negative regulation of cell proliferation GO:0008285 69 0.021
negative regulation of cellular biosynthetic process GO:0031327 277 0.020
protein complex biogenesis GO:0070271 201 0.020
regulation of polysaccharide biosynthetic process GO:0032885 1 0.020
regulation of smoothened signaling pathway GO:0008589 28 0.020
embryonic morphogenesis GO:0048598 206 0.020
lipid biosynthetic process GO:0008610 46 0.020
cell cycle checkpoint GO:0000075 95 0.020
regulation of epithelial cell proliferation GO:0050678 4 0.019
regulation of cell death GO:0010941 173 0.019
wing disc morphogenesis GO:0007472 344 0.019
tricarboxylic acid metabolic process GO:0072350 1 0.019
response to organic cyclic compound GO:0014070 89 0.019
hematopoietic progenitor cell differentiation GO:0002244 1 0.019
skeletal muscle fiber development GO:0048741 3 0.019
anion transport GO:0006820 41 0.019
signal transduction by phosphorylation GO:0023014 107 0.019
axonogenesis GO:0007409 290 0.018
cellular lipid metabolic process GO:0044255 83 0.018
positive regulation of innate immune response GO:0045089 38 0.018
mrna metabolic process GO:0016071 124 0.018
epithelial cell differentiation GO:0030855 322 0.018
response to molecule of bacterial origin GO:0002237 7 0.018
cellular response to molecule of bacterial origin GO:0071219 3 0.018
dna biosynthetic process GO:0071897 24 0.018
camera type eye morphogenesis GO:0048593 2 0.018
regulation of intracellular transport GO:0032386 64 0.018
regulation of hydrolase activity GO:0051336 97 0.018
response to decreased oxygen levels GO:0036293 58 0.018
reactive oxygen species metabolic process GO:0072593 22 0.017
regulation of response to external stimulus GO:0032101 115 0.017
generation of precursor metabolites and energy GO:0006091 42 0.017
response to lipid GO:0033993 38 0.017
cell substrate adhesion GO:0031589 10 0.017
glycosyl compound catabolic process GO:1901658 112 0.017
cell aging GO:0007569 2 0.017
protein targeting to nucleus GO:0044744 51 0.017
phagocytosis GO:0006909 215 0.017
response to radiation GO:0009314 155 0.017
respiratory system development GO:0060541 213 0.017
skeletal muscle organ development GO:0060538 48 0.017
positive regulation of transcription dna templated GO:0045893 266 0.017
positive regulation of phosphorus metabolic process GO:0010562 139 0.017
epiboly involved in wound healing GO:0090505 2 0.017
developmental growth GO:0048589 280 0.017
Worm
negative regulation of rna biosynthetic process GO:1902679 240 0.017
positive regulation of macromolecule biosynthetic process GO:0010557 283 0.017
regulation of catalytic activity GO:0050790 185 0.016
cell adhesion GO:0007155 136 0.016
response to hypoxia GO:0001666 53 0.016
microtubule organizing center organization GO:0031023 168 0.016
cellular response to biotic stimulus GO:0071216 4 0.016
muscle structure development GO:0061061 224 0.016
regulation of mapk cascade GO:0043408 92 0.016
fatty acid metabolic process GO:0006631 20 0.015
regulation of bmp signaling pathway GO:0030510 23 0.015
sulfur compound biosynthetic process GO:0044272 16 0.015
immune response GO:0006955 246 0.015
establishment of protein localization GO:0045184 163 0.015
dorsal ventral pattern formation imaginal disc GO:0007450 51 0.015
carbohydrate derivative catabolic process GO:1901136 118 0.015
regulation of cell proliferation GO:0042127 163 0.015
camera type eye development GO:0043010 4 0.015
monocarboxylic acid catabolic process GO:0072329 10 0.015
negative regulation of smoothened signaling pathway GO:0045879 16 0.015
cell proliferation GO:0008283 299 0.015
carbohydrate biosynthetic process GO:0016051 17 0.015
mitotic dna damage checkpoint GO:0044773 74 0.015
cellular modified amino acid metabolic process GO:0006575 45 0.015
positive regulation of transport GO:0051050 92 0.014
myotube cell development GO:0014904 3 0.014
cell type specific apoptotic process GO:0097285 38 0.014
cellular nitrogen compound catabolic process GO:0044270 165 0.014
hindbrain development GO:0030902 2 0.014
immune system process GO:0002376 347 0.014
mapk cascade GO:0000165 107 0.014
defense response GO:0006952 300 0.014
positive regulation of transcription from rna polymerase ii promoter GO:0045944 204 0.014
positive regulation of rna biosynthetic process GO:1902680 266 0.014
eye morphogenesis GO:0048592 260 0.014
regulation of humoral immune response GO:0002920 51 0.014
epidermal growth factor receptor signaling pathway GO:0007173 58 0.014
response to ethanol GO:0045471 59 0.014
ameboidal type cell migration GO:0001667 151 0.014
tor signaling GO:0031929 32 0.014
ribonucleotide metabolic process GO:0009259 145 0.013
positive regulation of defense response GO:0031349 59 0.013
purine ribonucleoside triphosphate catabolic process GO:0009207 108 0.013
negative regulation of developmental process GO:0051093 201 0.013
positive regulation of lipid biosynthetic process GO:0046889 3 0.013
regulation of stress activated mapk cascade GO:0032872 41 0.013
defense response to gram negative bacterium GO:0050829 94 0.013
cellular response to radiation GO:0071478 52 0.013
mitotic g2 m transition checkpoint GO:0044818 70 0.013
regulation of innate immune response GO:0045088 71 0.013
endomembrane system organization GO:0010256 119 0.013
kidney development GO:0001822 3 0.013
negative regulation of transforming growth factor beta receptor signaling pathway GO:0030512 4 0.013
purine nucleoside catabolic process GO:0006152 112 0.013
kidney epithelium development GO:0072073 3 0.012
sleep GO:0030431 49 0.012
regulation of anatomical structure size GO:0090066 163 0.012
regulation of neurogenesis GO:0050767 158 0.012
organonitrogen compound catabolic process GO:1901565 128 0.012
ubiquitin dependent protein catabolic process GO:0006511 78 0.012
regulation of cell substrate adhesion GO:0010810 2 0.012
positive regulation of gene expression GO:0010628 290 0.012
regulation of protein import into nucleus GO:0042306 28 0.012
activation of innate immune response GO:0002218 4 0.012
divalent metal ion transport GO:0070838 26 0.012
negative regulation of catalytic activity GO:0043086 42 0.012
regulation of steroid metabolic process GO:0019218 2 0.012
regulation of secretion GO:0051046 44 0.012
regulation of protein metabolic process GO:0051246 256 0.012
positive regulation of cellular component organization GO:0051130 156 0.012
morphogenesis of embryonic epithelium GO:0016331 94 0.012
nephron development GO:0072006 3 0.012
purine ribonucleoside metabolic process GO:0046128 127 0.012
aromatic compound catabolic process GO:0019439 166 0.012
organelle assembly GO:0070925 198 0.012
regulation of multicellular organism growth GO:0040014 40 0.012
Worm
regulation of hormone levels GO:0010817 40 0.011
nucleobase containing compound transport GO:0015931 56 0.011
response to ionizing radiation GO:0010212 32 0.011
defense response to bacterium GO:0042742 178 0.011
regulation of catabolic process GO:0009894 170 0.011
regulation of autophagy GO:0010506 62 0.011
regulation of proteolysis GO:0030162 87 0.011
negative regulation of proteolysis GO:0045861 31 0.011
wing disc pattern formation GO:0035222 66 0.011
regulation of transmembrane receptor protein serine threonine kinase signaling pathway GO:0090092 38 0.011
positive regulation of protein import into nucleus GO:0042307 21 0.011
chemical homeostasis GO:0048878 92 0.011
positive regulation of multicellular organismal process GO:0051240 143 0.011
Worm
imaginal disc pattern formation GO:0007447 91 0.011
stress activated mapk cascade GO:0051403 52 0.011
positive regulation of catalytic activity GO:0043085 118 0.011
response to hexose GO:0009746 3 0.011
stem cell development GO:0048864 79 0.011
positive regulation of developmental growth GO:0048639 62 0.011
Worm
nuclear transport GO:0051169 72 0.011
negative regulation of wnt signaling pathway GO:0030178 28 0.011
retina development in camera type eye GO:0060041 4 0.011
centrosome organization GO:0051297 163 0.011
regulation of cellular response to insulin stimulus GO:1900076 17 0.011
chemosensory behavior GO:0007635 106 0.010
forebrain development GO:0030900 2 0.010
neuron apoptotic process GO:0051402 17 0.010
regulation of cytoplasmic transport GO:1903649 47 0.010
negative regulation of immune response GO:0050777 39 0.010
wound healing spreading of epidermal cells GO:0035313 1 0.010
positive regulation of peptidyl tyrosine phosphorylation GO:0050731 4 0.010
ribose phosphate metabolic process GO:0019693 145 0.010
negative regulation of intracellular signal transduction GO:1902532 57 0.010
cellular response to ionizing radiation GO:0071479 15 0.010
jak stat cascade GO:0007259 49 0.010

Indy disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in fly and predicted with the fly functional network.

Disease DO term ID Size Probability Func Analog Org
cancer DOID:162 0 0.048
disease of cellular proliferation DOID:14566 0 0.048
organ system cancer DOID:0050686 0 0.048
disease of anatomical entity DOID:7 0 0.043
musculoskeletal system disease DOID:17 0 0.018
cardiovascular system disease DOID:1287 0 0.016